LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 Gene3D G3DSA:2.120.10.90 514 809 7.9E-44 T 06-07-2017 LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 Gene3D G3DSA:3.30.1360.40 248 345 3.3E-27 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 43 483 2.2E-147 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 SUPERFAMILY SSF56719 42 499 5.23E-165 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 SUPERFAMILY SSF101904 514 797 6.02E-42 T 06-07-2017 LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 SMART SM00434 22 477 3.5E-263 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 Gene3D G3DSA:3.90.199.10 346 411 4.8E-111 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 Gene3D G3DSA:3.90.199.10 42 247 4.8E-111 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 566 584 3.6 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 741 772 0.0098 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LK06_RS25365 4dc3cbe23bc72af54089abf332b4c755 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 670 715 1.0E-5 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 Gene3D G3DSA:1.10.10.10 160 221 4.9E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 Gene3D G3DSA:3.40.50.2300 9 159 1.0E-41 T 06-07-2017 LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 Pfam PF00072 Response regulator receiver domain 13 124 4.1E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 4.7E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 2.0E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 2.0E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 2.0E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 SMART SM00448 11 124 7.1E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 SMART SM00421 159 216 3.0E-28 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS25315 836690a013b4aea672d7d191f3a74afa 227 SUPERFAMILY SSF52172 9 185 3.77E-36 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS01790 1c9aa8e571b9bf4a3aa845ec2e767278 327 Gene3D G3DSA:3.40.50.720 150 246 4.6E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01790 1c9aa8e571b9bf4a3aa845ec2e767278 327 SMART SM00829 10 324 3.1E-38 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS01790 1c9aa8e571b9bf4a3aa845ec2e767278 327 Pfam PF13602 Zinc-binding dehydrogenase 187 324 2.2E-23 T 06-07-2017 LK06_RS01790 1c9aa8e571b9bf4a3aa845ec2e767278 327 SUPERFAMILY SSF51735 116 294 1.8E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01790 1c9aa8e571b9bf4a3aa845ec2e767278 327 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 LK06_RS01790 1c9aa8e571b9bf4a3aa845ec2e767278 327 Gene3D G3DSA:3.90.180.10 1 149 3.0E-45 T 06-07-2017 IPR011032 GroES-like LK06_RS01790 1c9aa8e571b9bf4a3aa845ec2e767278 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 85 3.3E-9 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS01790 1c9aa8e571b9bf4a3aa845ec2e767278 327 SUPERFAMILY SSF50129 1 148 4.57E-39 T 06-07-2017 IPR011032 GroES-like LK06_RS29675 8a7e19278f9612be1283adfc319bc1d1 264 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 256 7.7E-36 T 06-07-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase LK06_RS13395 f528e176e590582dd44252be3744eed2 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 159 178 2.8E-54 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 273 288 2.8E-54 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 248 264 2.8E-54 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 128 142 2.8E-54 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 197 216 2.8E-54 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 303 322 2.8E-54 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 248 260 - T 06-07-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 SMART SM01004 7 329 6.0E-209 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 SUPERFAMILY SSF51569 6 329 9.67E-128 T 06-07-2017 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 PIRSF PIRSF001415 1 330 2.5E-143 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 Pfam PF00490 Delta-aminolevulinic acid dehydratase 10 327 7.8E-134 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13395 f528e176e590582dd44252be3744eed2 330 Gene3D G3DSA:3.20.20.70 6 329 7.3E-139 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS19145 caaa326fbecd4e60a0499aa1d64c1bd6 243 Gene3D G3DSA:3.40.50.300 18 236 1.2E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19145 caaa326fbecd4e60a0499aa1d64c1bd6 243 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS19145 caaa326fbecd4e60a0499aa1d64c1bd6 243 Pfam PF00005 ABC transporter 36 184 1.5E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS19145 caaa326fbecd4e60a0499aa1d64c1bd6 243 SMART SM00382 45 232 8.9E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS19145 caaa326fbecd4e60a0499aa1d64c1bd6 243 SUPERFAMILY SSF52540 20 236 2.73E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 SMART SM00388 263 330 8.5E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 SMART SM00304 195 255 4.1E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 Pfam PF00512 His Kinase A (phospho-acceptor) domain 264 330 1.7E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 SUPERFAMILY SSF47384 249 331 2.75E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 SUPERFAMILY SSF55874 319 484 1.44E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 SMART SM00387 373 486 3.8E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 Gene3D G3DSA:3.30.565.10 316 485 9.8E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 3.9E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 438 3.9E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 3.9E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 3.9E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 484 9.3E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 Pfam PF00672 HAMP domain 176 251 3.1E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS04655 9ccc7081e47ab3fcbb9ba8c206cef586 498 Gene3D G3DSA:1.10.287.130 255 315 9.0E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS04700 f9349c081f7c0e89e64785547381de4b 306 PIRSF PIRSF000728 20 300 4.8E-99 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS04700 f9349c081f7c0e89e64785547381de4b 306 Pfam PF00696 Amino acid kinase family 36 277 1.8E-47 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS04700 f9349c081f7c0e89e64785547381de4b 306 TIGRFAM TIGR00761 argB: acetylglutamate kinase 37 274 1.5E-73 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS04700 f9349c081f7c0e89e64785547381de4b 306 SUPERFAMILY SSF53633 14 301 2.36E-86 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS04700 f9349c081f7c0e89e64785547381de4b 306 PRINTS PR00474 Glutamate 5-kinase family signature 250 270 1.8E-8 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 LK06_RS04700 f9349c081f7c0e89e64785547381de4b 306 PRINTS PR00474 Glutamate 5-kinase family signature 199 226 1.8E-8 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 LK06_RS04700 f9349c081f7c0e89e64785547381de4b 306 PRINTS PR00474 Glutamate 5-kinase family signature 66 80 1.8E-8 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 LK06_RS04700 f9349c081f7c0e89e64785547381de4b 306 Gene3D G3DSA:3.40.1160.10 33 299 3.9E-98 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS04700 f9349c081f7c0e89e64785547381de4b 306 Hamap MF_00082_B Acetylglutamate kinase [argB]. 33 300 34.655 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS07860 51f06421ed5f90f355270a1f9b199dfe 321 Hamap MF_00206 Lipoyl synthase [lipA]. 1 313 134.117 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LK06_RS07860 51f06421ed5f90f355270a1f9b199dfe 321 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 61 3.1E-7 T 06-07-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LK06_RS07860 51f06421ed5f90f355270a1f9b199dfe 321 Gene3D G3DSA:3.20.20.70 39 308 6.8E-65 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS07860 51f06421ed5f90f355270a1f9b199dfe 321 TIGRFAM TIGR00510 lipA: lipoyl synthase 18 311 4.3E-95 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LK06_RS07860 51f06421ed5f90f355270a1f9b199dfe 321 SUPERFAMILY SSF102114 36 315 4.58E-61 T 06-07-2017 LK06_RS07860 51f06421ed5f90f355270a1f9b199dfe 321 Pfam PF04055 Radical SAM superfamily 82 240 1.5E-11 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS07860 51f06421ed5f90f355270a1f9b199dfe 321 PIRSF PIRSF005963 3 320 1.1E-119 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LK06_RS07860 51f06421ed5f90f355270a1f9b199dfe 321 SMART SM00729 72 286 4.7E-12 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS02300 5a2e21f02529be748a7885887baed866 224 PIRSF PIRSF009467 1 224 1.2E-43 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 LK06_RS02300 5a2e21f02529be748a7885887baed866 224 Pfam PF01730 UreF 36 174 1.6E-18 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 LK06_RS02300 5a2e21f02529be748a7885887baed866 224 Hamap MF_01385 Urease accessory protein UreF [ureF]. 2 224 18.249 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 Gene3D G3DSA:1.10.1740.10 330 413 9.3E-28 T 06-07-2017 LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 Gene3D G3DSA:3.40.50.720 25 177 5.0E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 27 416 4.9E-111 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 SUPERFAMILY SSF51735 26 177 3.9E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 Pfam PF13288 DXP reductoisomerase C-terminal domain 290 407 4.3E-30 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 SUPERFAMILY SSF69055 319 414 3.27E-24 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 29 412 43.672 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 29 161 4.0E-39 T 06-07-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 SUPERFAMILY SSF55347 155 291 8.5E-53 T 06-07-2017 LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 PIRSF PIRSF006205 26 419 4.0E-140 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 LK06_RS24700 0f7f2b630ad9223bad6afec78513aabe 423 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 173 256 6.5E-36 T 06-07-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 ProSitePatterns PS00211 ABC transporters family signature. 716 730 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 418 526 7.2E-16 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 Pfam PF00005 ABC transporter 604 744 4.5E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 Gene3D G3DSA:3.40.50.1820 55 321 7.6E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 SUPERFAMILY SSF52540 576 806 7.79E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 59 201 1.9E-20 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 59 201 2.2E-20 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 Gene3D G3DSA:2.60.120.260 410 544 3.3E-24 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 SMART SM00939 313 549 1.6E-25 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 SUPERFAMILY SSF49785 354 534 1.57E-27 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 SUPERFAMILY SSF53474 49 325 9.59E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 Gene3D G3DSA:3.40.50.300 577 804 1.4E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10425 102ad17e569cf1de1afac88b23f93faf 886 SMART SM00382 612 792 1.4E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS19865 7b7094d88f5903ef321f7308f447c06b 366 SMART SM00860 170 308 7.5E-5 T 06-07-2017 IPR018958 SMI1/KNR4-like domain LK06_RS19865 7b7094d88f5903ef321f7308f447c06b 366 Gene3D G3DSA:3.40.1580.10 169 202 1.0E-5 T 06-07-2017 IPR018958 SMI1/KNR4-like domain LK06_RS19865 7b7094d88f5903ef321f7308f447c06b 366 SUPERFAMILY SSF160631 158 309 3.53E-15 T 06-07-2017 LK06_RS19865 7b7094d88f5903ef321f7308f447c06b 366 Pfam PF14414 A nuclease of the HNH/ENDO VII superfamily with conserved WHH 106 143 2.2E-12 T 06-07-2017 IPR032869 WHH domain-containing protein LK06_RS19865 7b7094d88f5903ef321f7308f447c06b 366 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 171 307 1.6E-8 T 06-07-2017 IPR018958 SMI1/KNR4-like domain LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 Gene3D G3DSA:2.40.50.100 1046 1100 9.8E-8 T 06-07-2017 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1265 10.022 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 SMART SM00663 310 589 6.6E-174 T 06-07-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1256 0.0 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 Pfam PF04998 RNA polymerase Rpb1, domain 5 843 1204 1.5E-66 T 06-07-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 736 3.9E-22 T 06-07-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 Gene3D G3DSA:2.40.40.20 492 564 3.7E-38 T 06-07-2017 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 Gene3D G3DSA:2.40.40.20 424 451 3.7E-38 T 06-07-2017 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 Pfam PF05000 RNA polymerase Rpb1, domain 4 765 829 7.9E-14 T 06-07-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 SUPERFAMILY SSF64484 5 1256 0.0 T 06-07-2017 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 480 1.3E-8 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 Pfam PF00623 RNA polymerase Rpb1, domain 2 468 560 9.6E-28 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12420 67769dddcbdae0589a2723853f4e1090 1304 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 3.4E-82 T 06-07-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS22345 3ec842f191cff70d9f98157739b02f55 201 Gene3D G3DSA:1.10.357.10 4 118 4.0E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS22345 3ec842f191cff70d9f98157739b02f55 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.4E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS22345 3ec842f191cff70d9f98157739b02f55 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.4E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS22345 3ec842f191cff70d9f98157739b02f55 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 4.1E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS22345 3ec842f191cff70d9f98157739b02f55 201 SUPERFAMILY SSF46689 3 80 4.99E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS03210 089be379b63457a1cf7ffdee7d9d9f75 282 SUPERFAMILY SSF51735 6 273 2.71E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03210 089be379b63457a1cf7ffdee7d9d9f75 282 Gene3D G3DSA:3.40.50.720 4 214 3.0E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03210 089be379b63457a1cf7ffdee7d9d9f75 282 Pfam PF05368 NmrA-like family 129 215 3.1E-5 T 06-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 LK06_RS03210 089be379b63457a1cf7ffdee7d9d9f75 282 Pfam PF13460 NAD(P)H-binding 11 107 1.4E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00160 b0ac99c3000f818e2fff27108973d8f6 364 Pfam PF02163 Peptidase family M50 129 176 1.5E-8 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 LK06_RS00160 b0ac99c3000f818e2fff27108973d8f6 364 PIRSF PIRSF006404 1 364 9.4E-89 T 06-07-2017 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS LK06_RS00160 b0ac99c3000f818e2fff27108973d8f6 364 SUPERFAMILY SSF54631 232 357 1.1E-21 T 06-07-2017 LK06_RS00160 b0ac99c3000f818e2fff27108973d8f6 364 Pfam PF00571 CBS domain 301 357 3.9E-8 T 06-07-2017 IPR000644 CBS domain LK06_RS00160 b0ac99c3000f818e2fff27108973d8f6 364 Pfam PF00571 CBS domain 236 288 2.7E-5 T 06-07-2017 IPR000644 CBS domain LK06_RS00160 b0ac99c3000f818e2fff27108973d8f6 364 Gene3D G3DSA:3.10.580.10 235 356 8.6E-18 T 06-07-2017 LK06_RS00160 b0ac99c3000f818e2fff27108973d8f6 364 SMART SM00116 243 293 2.3 T 06-07-2017 IPR000644 CBS domain LK06_RS00160 b0ac99c3000f818e2fff27108973d8f6 364 SMART SM00116 310 357 2.2E-6 T 06-07-2017 IPR000644 CBS domain LK06_RS18815 e4d2b480b7a2acc15978708559156e2a 305 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 241 2.1E-35 T 06-07-2017 LK06_RS18815 e4d2b480b7a2acc15978708559156e2a 305 SUPERFAMILY SSF51735 5 249 3.97E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS18815 e4d2b480b7a2acc15978708559156e2a 305 Gene3D G3DSA:3.40.50.720 3 254 4.2E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS18815 e4d2b480b7a2acc15978708559156e2a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18815 e4d2b480b7a2acc15978708559156e2a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18815 e4d2b480b7a2acc15978708559156e2a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18815 e4d2b480b7a2acc15978708559156e2a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18815 e4d2b480b7a2acc15978708559156e2a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18815 e4d2b480b7a2acc15978708559156e2a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18815 e4d2b480b7a2acc15978708559156e2a 305 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 198 2.5E-5 T 06-07-2017 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 Gene3D G3DSA:3.30.470.20 188 428 1.4E-85 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 5.4E-43 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 SUPERFAMILY SSF52440 2 113 1.01E-46 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 SUPERFAMILY SSF56059 83 316 3.54E-58 T 06-07-2017 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 Gene3D G3DSA:3.30.1490.20 133 187 7.4E-21 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 Pfam PF00364 Biotin-requiring enzyme 547 611 2.0E-14 T 06-07-2017 IPR000089 Biotin/lipoyl attachment LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 SUPERFAMILY SSF51230 539 612 1.27E-17 T 06-07-2017 IPR011053 Single hybrid motif LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 Gene3D G3DSA:3.40.50.20 2 123 1.0E-46 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 270 277 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 SUPERFAMILY SSF51246 312 427 2.46E-34 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 133 305 1.2E-60 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 Gene3D G3DSA:2.40.50.100 543 612 1.3E-21 T 06-07-2017 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 Pfam PF02785 Biotin carboxylase C-terminal domain 318 422 2.2E-30 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 569 586 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS18660 eec3674ee77531f5eed13e48e3210824 617 SMART SM00878 318 422 7.6E-46 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 Gene3D G3DSA:3.30.365.10 371 464 1.0E-70 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 Gene3D G3DSA:3.30.365.10 635 784 1.0E-70 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 SMART SM01008 24 139 6.9E-46 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 Gene3D G3DSA:3.90.1170.50 7 127 2.6E-37 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 24 139 3.3E-25 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 SUPERFAMILY SSF56003 131 784 2.49E-204 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 Gene3D G3DSA:3.30.365.10 185 290 2.1E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 Gene3D G3DSA:3.30.365.10 128 184 9.8E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 Gene3D G3DSA:3.30.365.10 293 368 9.8E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 159 720 7.9E-175 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 Gene3D G3DSA:3.30.365.10 465 632 8.9E-46 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS00955 4feada6d238df5ca4483a73f51d483c8 807 SUPERFAMILY SSF54665 8 159 2.88E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 SUPERFAMILY SSF52540 350 628 3.97E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 Pfam PF07497 Rho termination factor, RNA-binding domain 312 386 6.5E-30 T 06-07-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 Gene3D G3DSA:3.40.50.300 392 675 3.5E-99 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 Gene3D G3DSA:2.40.50.140 307 386 5.2E-42 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 Gene3D G3DSA:2.40.50.140 40 79 5.2E-42 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 SMART SM00357 313 379 6.1E-11 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 Hamap MF_01884 Transcription termination factor Rho [rho]. 302 677 206.282 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 SMART SM00959 39 80 8.7E-11 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 417 621 3.7E-20 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 Pfam PF07498 Rho termination factor, N-terminal domain 40 78 2.3E-11 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 SUPERFAMILY SSF68912 39 78 6.28E-5 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 TIGRFAM TIGR00767 rho: transcription termination factor Rho 40 675 6.9E-201 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 SUPERFAMILY SSF50249 312 386 2.23E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS23225 ca9003027c0ea2d28ed8ac22525b004c 685 SMART SM00382 428 613 1.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 Gene3D G3DSA:3.40.47.10 4 124 1.6E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 Gene3D G3DSA:3.40.47.10 196 268 1.6E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 Pfam PF02803 Thiolase, C-terminal domain 263 384 1.6E-43 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 Pfam PF00108 Thiolase, N-terminal domain 5 254 1.6E-60 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 383 1.5E-126 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 Gene3D G3DSA:3.40.47.10 269 384 5.5E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 Gene3D G3DSA:3.40.47.10 158 195 5.5E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 SUPERFAMILY SSF53901 3 262 1.81E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 SUPERFAMILY SSF53901 264 384 5.61E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 ProSitePatterns PS00737 Thiolases signature 2. 331 347 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 LK06_RS07005 6e1814933395c2b89b140358caf2a851 385 PIRSF PIRSF000429 1 385 1.1E-123 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS26620 8d9ca8d4f19f9d0ea37b82adfc315a64 355 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 17 351 7.9E-128 T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LK06_RS26620 8d9ca8d4f19f9d0ea37b82adfc315a64 355 Gene3D G3DSA:3.20.20.210 15 351 5.0E-144 T 06-07-2017 LK06_RS26620 8d9ca8d4f19f9d0ea37b82adfc315a64 355 SUPERFAMILY SSF51726 15 351 2.96E-105 T 06-07-2017 LK06_RS26620 8d9ca8d4f19f9d0ea37b82adfc315a64 355 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 33 42 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LK06_RS26620 8d9ca8d4f19f9d0ea37b82adfc315a64 355 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 150 166 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LK06_RS26620 8d9ca8d4f19f9d0ea37b82adfc315a64 355 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 17 353 47.589 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LK06_RS26620 8d9ca8d4f19f9d0ea37b82adfc315a64 355 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 20 350 3.8E-124 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LK06_RS12755 1fe6b19aa80c82bc150d30faec044391 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 9 236 6.5E-18 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 LK06_RS12755 1fe6b19aa80c82bc150d30faec044391 270 SUPERFAMILY SSF56784 7 268 3.56E-57 T 06-07-2017 IPR023214 HAD-like domain LK06_RS12755 1fe6b19aa80c82bc150d30faec044391 270 Gene3D G3DSA:3.40.50.1000 7 77 2.3E-47 T 06-07-2017 IPR023214 HAD-like domain LK06_RS12755 1fe6b19aa80c82bc150d30faec044391 270 Gene3D G3DSA:3.40.50.1000 172 268 2.3E-47 T 06-07-2017 IPR023214 HAD-like domain LK06_RS12755 1fe6b19aa80c82bc150d30faec044391 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 10 263 7.3E-45 T 06-07-2017 IPR023214 HAD-like domain LK06_RS01305 346832a63fb2d68cfee557c3b44f58c7 213 SUPERFAMILY SSF100950 41 212 2.09E-39 T 06-07-2017 LK06_RS01305 346832a63fb2d68cfee557c3b44f58c7 213 Gene3D G3DSA:3.40.50.10420 42 212 2.6E-55 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain LK06_RS01305 346832a63fb2d68cfee557c3b44f58c7 213 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 47 212 3.4E-21 T 06-07-2017 IPR003741 LUD domain LK06_RS13595 02f8a275dc8c1f2e6a8974160a234e6c 374 SUPERFAMILY SSF47781 297 366 1.07E-12 T 06-07-2017 IPR010994 RuvA domain 2-like LK06_RS13595 02f8a275dc8c1f2e6a8974160a234e6c 374 Gene3D G3DSA:3.40.1700.10 32 154 1.1E-28 T 06-07-2017 LK06_RS13595 02f8a275dc8c1f2e6a8974160a234e6c 374 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 16 371 44.198 T 06-07-2017 IPR023763 DNA integrity scanning protein, DisA LK06_RS13595 02f8a275dc8c1f2e6a8974160a234e6c 374 Pfam PF10635 DisA bacterial checkpoint controller linker region 155 297 1.7E-52 T 06-07-2017 IPR018906 DNA integrity scanning, DisA, linker region LK06_RS13595 02f8a275dc8c1f2e6a8974160a234e6c 374 Gene3D G3DSA:1.10.150.20 311 361 5.5E-12 T 06-07-2017 LK06_RS13595 02f8a275dc8c1f2e6a8974160a234e6c 374 Pfam PF12826 Helix-hairpin-helix motif 324 361 1.1E-6 T 06-07-2017 LK06_RS13595 02f8a275dc8c1f2e6a8974160a234e6c 374 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 38 151 1.1E-21 T 06-07-2017 IPR003390 DNA integrity scanning protein, DisA, N-terminal LK06_RS13595 02f8a275dc8c1f2e6a8974160a234e6c 374 SUPERFAMILY SSF143597 32 154 9.02E-26 T 06-07-2017 LK06_RS00445 d1f251c791b77514d82e4d71adc66edb 530 Gene3D G3DSA:3.30.465.10 158 275 1.7E-23 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS00445 d1f251c791b77514d82e4d71adc66edb 530 SUPERFAMILY SSF55103 282 529 2.13E-40 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LK06_RS00445 d1f251c791b77514d82e4d71adc66edb 530 Pfam PF02913 FAD linked oxidases, C-terminal domain 275 524 9.2E-49 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LK06_RS00445 d1f251c791b77514d82e4d71adc66edb 530 Gene3D G3DSA:1.10.45.10 487 524 2.8E-7 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 LK06_RS00445 d1f251c791b77514d82e4d71adc66edb 530 Gene3D G3DSA:3.30.43.10 54 155 4.3E-20 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS00445 d1f251c791b77514d82e4d71adc66edb 530 SUPERFAMILY SSF56176 52 275 1.45E-51 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS00445 d1f251c791b77514d82e4d71adc66edb 530 Pfam PF01565 FAD binding domain 100 238 1.3E-35 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LK06_RS20740 97473b05a211776d63ca1e9b5676ae66 395 Hamap MF_00540 Adenosine deaminase [add]. 23 368 55.512 T 06-07-2017 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 LK06_RS20740 97473b05a211776d63ca1e9b5676ae66 395 SUPERFAMILY SSF51556 23 362 8.51E-70 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS20740 97473b05a211776d63ca1e9b5676ae66 395 Gene3D G3DSA:3.20.20.140 25 367 2.2E-102 T 06-07-2017 LK06_RS20740 97473b05a211776d63ca1e9b5676ae66 395 Pfam PF00962 Adenosine/AMP deaminase 28 365 6.3E-87 T 06-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 LK06_RS20740 97473b05a211776d63ca1e9b5676ae66 395 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 29 365 3.6E-72 T 06-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 LK06_RS13910 ee579609335738548df4376788e845fc 1088 Pfam PF00486 Transcriptional regulatory protein, C terminal 62 119 2.5E-8 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS13910 ee579609335738548df4376788e845fc 1088 SUPERFAMILY SSF46894 56 128 2.66E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS13910 ee579609335738548df4376788e845fc 1088 SMART SM00862 57 128 1.3E-11 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS13910 ee579609335738548df4376788e845fc 1088 SUPERFAMILY SSF48452 130 293 4.93E-26 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS13910 ee579609335738548df4376788e845fc 1088 PRINTS PR00364 Disease resistance protein signature 375 390 1.5E-7 T 06-07-2017 LK06_RS13910 ee579609335738548df4376788e845fc 1088 PRINTS PR00364 Disease resistance protein signature 454 468 1.5E-7 T 06-07-2017 LK06_RS13910 ee579609335738548df4376788e845fc 1088 PRINTS PR00364 Disease resistance protein signature 535 549 1.5E-7 T 06-07-2017 LK06_RS13910 ee579609335738548df4376788e845fc 1088 Pfam PF13424 Tetratricopeptide repeat 884 949 1.0E-8 T 06-07-2017 LK06_RS13910 ee579609335738548df4376788e845fc 1088 Gene3D G3DSA:3.40.50.300 356 470 1.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13910 ee579609335738548df4376788e845fc 1088 SMART SM01043 135 282 2.2E-42 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS13910 ee579609335738548df4376788e845fc 1088 SUPERFAMILY SSF52540 337 553 1.64E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13910 ee579609335738548df4376788e845fc 1088 SMART SM00028 921 953 180.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS13910 ee579609335738548df4376788e845fc 1088 SMART SM00028 960 993 0.44 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS13910 ee579609335738548df4376788e845fc 1088 SMART SM00028 1040 1073 210.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS13910 ee579609335738548df4376788e845fc 1088 SMART SM00028 841 874 100.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS13910 ee579609335738548df4376788e845fc 1088 SMART SM00028 881 914 0.31 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS13910 ee579609335738548df4376788e845fc 1088 Gene3D G3DSA:1.10.10.10 62 129 1.6E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13910 ee579609335738548df4376788e845fc 1088 Pfam PF00931 NB-ARC domain 361 553 1.7E-10 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 LK06_RS13910 ee579609335738548df4376788e845fc 1088 Pfam PF03704 Bacterial transcriptional activator domain 135 282 5.4E-39 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS13910 ee579609335738548df4376788e845fc 1088 Gene3D G3DSA:1.25.40.10 828 896 3.5E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS13910 ee579609335738548df4376788e845fc 1088 Gene3D G3DSA:1.25.40.10 897 1076 4.0E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS13910 ee579609335738548df4376788e845fc 1088 SUPERFAMILY SSF48452 839 1035 2.09E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS14960 4259d7e2e395f383a9367d72eac5c8ae 270 Gene3D G3DSA:3.40.50.150 27 206 1.5E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS14960 4259d7e2e395f383a9367d72eac5c8ae 270 Pfam PF13649 Methyltransferase domain 50 145 1.9E-20 T 06-07-2017 LK06_RS14960 4259d7e2e395f383a9367d72eac5c8ae 270 SUPERFAMILY SSF53335 13 261 1.06E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00823 Phosphopantetheine attachment site 4138 4210 2.0E-30 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00823 Phosphopantetheine attachment site 927 999 4.0E-23 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00823 Phosphopantetheine attachment site 2633 2705 6.3E-34 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4165 4180 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF00698 Acyl transferase domain 3281 3598 1.7E-86 T 06-07-2017 IPR014043 Acyl transferase LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF00698 Acyl transferase domain 1553 1870 7.0E-94 T 06-07-2017 IPR014043 Acyl transferase LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF00698 Acyl transferase domain 536 819 2.1E-55 T 06-07-2017 IPR014043 Acyl transferase LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF51735 2355 2584 4.79E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2891 2907 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF55048 665 728 7.72E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF47336 4131 4212 7.07E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00825 Beta-ketoacyl synthase 1019 1444 3.7E-221 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00825 Beta-ketoacyl synthase 2730 3155 1.1E-225 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00825 Beta-ketoacyl synthase 22 439 3.5E-179 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 538 836 1.5E-105 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1555 1852 1.0E-122 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3282 3580 2.0E-116 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF53901 17 379 8.59E-82 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.50.720 3854 4066 7.2E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 20 264 1.7E-71 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1017 1267 1.8E-91 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2728 2978 1.3E-91 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2356 2531 2.2E-49 T 06-07-2017 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3854 4034 3.7E-34 T 06-07-2017 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM01294 2635 2701 2.7E-5 T 06-07-2017 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM01294 928 995 1.3E-4 T 06-07-2017 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM01294 4139 4206 7.3E-6 T 06-07-2017 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF08659 KR domain 2356 2530 9.0E-53 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF08659 KR domain 3856 4032 1.9E-49 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.366.10 1541 1675 1.2E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.366.10 531 661 2.5E-69 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.366.10 729 851 2.5E-69 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.366.10 1743 1864 1.2E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.366.10 3271 3405 2.5E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.366.10 3471 3593 2.5E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF52151 3472 3569 3.92E-66 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF52151 3278 3410 3.92E-66 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF00550 Phosphopantetheine attachment site 930 995 5.2E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF00550 Phosphopantetheine attachment site 2636 2701 1.7E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF00550 Phosphopantetheine attachment site 4141 4206 1.2E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.47.10 22 277 1.5E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.47.10 1019 1279 1.1E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.47.10 2730 2990 5.4E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2660 2675 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF52151 1744 1842 3.92E-69 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF52151 1551 1680 3.92E-69 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF51735 3636 3842 9.84E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF47336 921 1032 1.44E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF51735 2195 2343 5.64E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF51735 3852 4087 1.11E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1180 1196 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF53901 2725 3100 1.67E-102 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF14765 Polyketide synthase dehydratase 1918 2190 7.2E-59 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF55048 3408 3471 4.45E-13 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF55048 1679 1743 5.1E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF52151 534 666 7.32E-65 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF52151 730 818 7.32E-65 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:1.10.1200.10 4135 4211 3.4E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:1.10.1200.10 2632 2705 2.0E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:1.10.1200.10 924 1000 5.7E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF47336 2628 2742 5.23E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.50.720 2356 2534 3.8E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.30.70.250 3408 3470 4.8E-7 T 06-07-2017 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.30.70.250 1678 1742 1.1E-4 T 06-07-2017 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.30.70.250 664 728 4.1E-4 T 06-07-2017 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2986 3102 4.0E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1275 1391 3.2E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 273 386 3.1E-37 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1394 1515 1.4E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 389 484 1.4E-18 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3105 3243 7.6E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SUPERFAMILY SSF53901 1015 1389 9.33E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 SMART SM00826 1918 2077 3.4E-77 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.47.10 2991 3155 7.8E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.47.10 278 438 3.9E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29410 b1ac1491948fac6151f0eb7fa7825023 4277 Gene3D G3DSA:3.40.47.10 1280 1444 2.6E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 Gene3D G3DSA:1.10.150.20 92 142 6.3E-5 T 06-07-2017 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 Gene3D G3DSA:3.30.210.10 255 316 4.0E-24 T 06-07-2017 IPR029398 DNA polymerase beta, thumb domain LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 SUPERFAMILY SSF47802 4 84 3.79E-16 T 06-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 SUPERFAMILY SSF89550 338 571 1.44E-49 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 Pfam PF14520 Helix-hairpin-helix domain 92 143 2.9E-10 T 06-07-2017 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 Gene3D G3DSA:1.10.8.310 3 84 1.7E-18 T 06-07-2017 IPR027420 DNA polymerase beta, N-terminal domain LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 SMART SM00483 3 316 2.0E-18 T 06-07-2017 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 SMART SM00278 127 146 74.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 SMART SM00278 52 71 130.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 SMART SM00278 92 111 2.1 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 SMART SM00481 340 418 3.9E-12 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 254 261 2.1E-8 T 06-07-2017 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 239 247 2.1E-8 T 06-07-2017 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 59 76 2.1E-8 T 06-07-2017 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 298 315 2.1E-8 T 06-07-2017 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 Pfam PF14791 DNA polymerase beta thumb 255 316 1.8E-21 T 06-07-2017 IPR029398 DNA polymerase beta, thumb domain LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 Gene3D G3DSA:3.30.460.10 143 254 6.9E-14 T 06-07-2017 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 Pfam PF02811 PHP domain 341 445 1.5E-6 T 06-07-2017 IPR004013 PHP domain GO:0003824 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 SUPERFAMILY SSF81301 156 316 7.19E-38 T 06-07-2017 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 SUPERFAMILY SSF47781 92 145 3.78E-5 T 06-07-2017 IPR010994 RuvA domain 2-like LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 PIRSF PIRSF005047 3 573 1.4E-206 T 06-07-2017 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 Pfam PF14716 Helix-hairpin-helix domain 5 72 4.6E-19 T 06-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain LK06_RS05205 e51e08ad068e87bb89d4185740cf1bbe 575 Gene3D G3DSA:3.20.20.140 338 569 7.3E-47 T 06-07-2017 LK06_RS15130 b966e3ed04fc4933dbe25acb9b03dcde 178 Gene3D G3DSA:1.10.10.10 5 149 2.3E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15130 b966e3ed04fc4933dbe25acb9b03dcde 178 SUPERFAMILY SSF46785 11 152 7.64E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15130 b966e3ed04fc4933dbe25acb9b03dcde 178 SMART SM00347 36 136 9.4E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS15130 b966e3ed04fc4933dbe25acb9b03dcde 178 Pfam PF01047 MarR family 44 100 3.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 Gene3D G3DSA:2.60.34.10 366 508 1.2E-71 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 SUPERFAMILY SSF100934 484 579 4.58E-13 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 Pfam PF00012 Hsp70 protein 4 580 2.8E-237 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 Gene3D G3DSA:3.90.640.10 206 291 4.1E-31 T 06-07-2017 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.8E-73 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 PRINTS PR00301 70kDa heat shock protein signature 119 139 1.8E-73 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.8E-73 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 PRINTS PR00301 70kDa heat shock protein signature 178 188 1.8E-73 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 PRINTS PR00301 70kDa heat shock protein signature 364 383 1.8E-73 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.8E-73 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 PRINTS PR00301 70kDa heat shock protein signature 445 461 1.8E-73 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 PRINTS PR00301 70kDa heat shock protein signature 310 326 1.8E-73 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 PRINTS PR00301 70kDa heat shock protein signature 341 361 1.8E-73 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 Gene3D G3DSA:1.20.1270.10 509 580 8.2E-24 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 Gene3D G3DSA:3.30.30.30 39 105 6.9E-11 T 06-07-2017 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 172 185 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 SUPERFAMILY SSF53067 2 164 6.48E-55 T 06-07-2017 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 SUPERFAMILY SSF53067 166 357 3.01E-67 T 06-07-2017 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 580 6.6E-271 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 Gene3D G3DSA:3.30.420.40 4 38 9.8E-56 T 06-07-2017 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 Gene3D G3DSA:3.30.420.40 106 170 9.8E-56 T 06-07-2017 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 608 35.419 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 Gene3D G3DSA:3.30.420.40 171 205 1.6E-33 T 06-07-2017 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 Gene3D G3DSA:3.30.420.40 295 337 1.6E-33 T 06-07-2017 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 SUPERFAMILY SSF100920 360 516 8.5E-59 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 LK06_RS28160 37de37dc1b02ad1a7ed473a328a34afc 617 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 313 327 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LK06_RS27065 c084715767fe099d7f8b359335566eb4 448 SUPERFAMILY SSF102114 161 415 8.24E-10 T 06-07-2017 LK06_RS06285 648358c471bd3846d4ca9f84cb7835ce 195 SUPERFAMILY SSF63965 5 187 2.62E-54 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 LK06_RS06285 648358c471bd3846d4ca9f84cb7835ce 195 Gene3D G3DSA:3.40.50.10230 5 188 6.6E-62 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 LK06_RS06285 648358c471bd3846d4ca9f84cb7835ce 195 Pfam PF02570 Precorrin-8X methylmutase 8 186 1.8E-53 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 LK06_RS11305 93c1de40a78afe4a518c4660830656c9 164 Pfam PF01037 Lrp/AsnC ligand binding domain 73 138 3.8E-12 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS11305 93c1de40a78afe4a518c4660830656c9 164 SMART SM00344 3 109 1.3E-27 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS11305 93c1de40a78afe4a518c4660830656c9 164 SUPERFAMILY SSF46785 1 72 1.09E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11305 93c1de40a78afe4a518c4660830656c9 164 Gene3D G3DSA:1.10.10.10 1 53 1.1E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11305 93c1de40a78afe4a518c4660830656c9 164 Gene3D G3DSA:3.30.70.920 56 140 3.3E-17 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS11305 93c1de40a78afe4a518c4660830656c9 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 2.9E-10 T 06-07-2017 LK06_RS11305 93c1de40a78afe4a518c4660830656c9 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.0E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS11305 93c1de40a78afe4a518c4660830656c9 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.0E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS11305 93c1de40a78afe4a518c4660830656c9 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.0E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS11305 93c1de40a78afe4a518c4660830656c9 164 SUPERFAMILY SSF54909 63 148 4.16E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS01490 b81176237d14543dcc74c3b3b653c8ad 201 Gene3D G3DSA:1.10.357.10 14 193 4.9E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS01490 b81176237d14543dcc74c3b3b653c8ad 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01490 b81176237d14543dcc74c3b3b653c8ad 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01490 b81176237d14543dcc74c3b3b653c8ad 201 SUPERFAMILY SSF46689 14 83 8.03E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01490 b81176237d14543dcc74c3b3b653c8ad 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 3.3E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01490 b81176237d14543dcc74c3b3b653c8ad 201 SUPERFAMILY SSF48498 94 193 6.12E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS06280 4833b66e143e1a890a16a6b1d362cc66 564 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 318 553 8.2E-84 T 06-07-2017 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 LK06_RS06280 4833b66e143e1a890a16a6b1d362cc66 564 Gene3D G3DSA:3.40.1010.10 316 426 4.5E-22 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06280 4833b66e143e1a890a16a6b1d362cc66 564 SUPERFAMILY SSF159664 184 312 2.09E-34 T 06-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 LK06_RS06280 4833b66e143e1a890a16a6b1d362cc66 564 Pfam PF11760 Cobalamin synthesis G N-terminal 36 116 2.4E-32 T 06-07-2017 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 LK06_RS06280 4833b66e143e1a890a16a6b1d362cc66 564 Gene3D G3DSA:3.30.950.10 427 539 3.2E-14 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06280 4833b66e143e1a890a16a6b1d362cc66 564 Pfam PF01890 Cobalamin synthesis G C-terminus 191 309 5.2E-34 T 06-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 LK06_RS06280 4833b66e143e1a890a16a6b1d362cc66 564 Gene3D G3DSA:3.30.420.180 183 312 1.0E-34 T 06-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 LK06_RS06280 4833b66e143e1a890a16a6b1d362cc66 564 SUPERFAMILY SSF53790 313 554 7.46E-52 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06280 4833b66e143e1a890a16a6b1d362cc66 564 SUPERFAMILY SSF159672 3 197 7.32E-48 T 06-07-2017 LK06_RS06280 4833b66e143e1a890a16a6b1d362cc66 564 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 317 521 1.4E-38 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS05890 94767be7626325abd5462108e8c07ec4 313 Pfam PF01145 SPFH domain / Band 7 family 25 194 2.6E-35 T 06-07-2017 IPR001107 Band 7 domain LK06_RS05890 94767be7626325abd5462108e8c07ec4 313 SUPERFAMILY SSF117892 52 186 1.96E-39 T 06-07-2017 IPR001107 Band 7 domain LK06_RS05890 94767be7626325abd5462108e8c07ec4 313 SMART SM00244 21 179 1.7E-52 T 06-07-2017 IPR001107 Band 7 domain LK06_RS05890 94767be7626325abd5462108e8c07ec4 313 PRINTS PR00721 Stomatin signature 131 154 5.5E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS05890 94767be7626325abd5462108e8c07ec4 313 PRINTS PR00721 Stomatin signature 76 97 5.5E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS05890 94767be7626325abd5462108e8c07ec4 313 PRINTS PR00721 Stomatin signature 174 195 5.5E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS05890 94767be7626325abd5462108e8c07ec4 313 PRINTS PR00721 Stomatin signature 28 50 5.5E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS05890 94767be7626325abd5462108e8c07ec4 313 PRINTS PR00721 Stomatin signature 111 128 5.5E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS05890 94767be7626325abd5462108e8c07ec4 313 PRINTS PR00721 Stomatin signature 155 173 5.5E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS05890 94767be7626325abd5462108e8c07ec4 313 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 06-07-2017 IPR018080 Band 7/stomatin-like, conserved site LK06_RS06420 4f16cab832874a283bcd2fa858b2ce89 166 Pfam PF12277 Protein of unknown function (DUF3618) 12 56 4.3E-11 T 06-07-2017 IPR022062 Protein of unknown function DUF3618 LK06_RS24345 7220065793aceedf01a8630c88f913bd 1308 SUPERFAMILY SSF75553 495 580 8.5E-13 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 LK06_RS24345 7220065793aceedf01a8630c88f913bd 1308 Gene3D G3DSA:3.40.50.300 2 163 5.3E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24345 7220065793aceedf01a8630c88f913bd 1308 Gene3D G3DSA:3.40.50.300 1156 1303 5.3E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24345 7220065793aceedf01a8630c88f913bd 1308 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1308 22.228 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 LK06_RS24345 7220065793aceedf01a8630c88f913bd 1308 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 583 6.9E-13 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 LK06_RS24345 7220065793aceedf01a8630c88f913bd 1308 SMART SM00968 512 739 1.0E-21 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 LK06_RS24345 7220065793aceedf01a8630c88f913bd 1308 SUPERFAMILY SSF75553 700 783 2.88E-8 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 LK06_RS24345 7220065793aceedf01a8630c88f913bd 1308 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1300 1.1E-71 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal LK06_RS24345 7220065793aceedf01a8630c88f913bd 1308 SUPERFAMILY SSF52540 2 207 3.53E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24345 7220065793aceedf01a8630c88f913bd 1308 SUPERFAMILY SSF52540 1109 1299 3.53E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12600 6425b8d653bad46e5ae6b946ce9da26e 163 Pfam PF00589 Phage integrase family 69 135 6.3E-10 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS12600 6425b8d653bad46e5ae6b946ce9da26e 163 SUPERFAMILY SSF56349 86 139 2.91E-15 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS12600 6425b8d653bad46e5ae6b946ce9da26e 163 Gene3D G3DSA:1.10.443.10 35 140 9.2E-17 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS18480 cd1a129897a05e97422eb21630a0f5b2 447 Gene3D G3DSA:1.20.1250.20 75 220 4.5E-4 T 06-07-2017 LK06_RS18480 cd1a129897a05e97422eb21630a0f5b2 447 Pfam PF07690 Major Facilitator Superfamily 71 399 3.0E-12 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS18480 cd1a129897a05e97422eb21630a0f5b2 447 SUPERFAMILY SSF103473 73 426 1.14E-15 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS02660 5f700541af85afcef1cef2577e639367 346 Gene3D G3DSA:3.40.50.1820 33 342 5.3E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02660 5f700541af85afcef1cef2577e639367 346 SUPERFAMILY SSF53474 13 341 1.59E-74 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02660 5f700541af85afcef1cef2577e639367 346 PIRSF PIRSF000443 1 345 7.5E-79 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 LK06_RS02660 5f700541af85afcef1cef2577e639367 346 Pfam PF00561 alpha/beta hydrolase fold 50 325 4.9E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 Gene3D G3DSA:3.40.50.150 265 310 2.3E-61 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 Gene3D G3DSA:3.40.50.150 188 226 2.3E-61 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 Gene3D G3DSA:3.40.50.150 1 135 2.3E-61 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 SUPERFAMILY SSF53335 1 149 1.05E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 SUPERFAMILY SSF53335 187 225 1.05E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 SUPERFAMILY SSF53335 264 305 1.05E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 5 10 - T 06-07-2017 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 Pfam PF01555 DNA methylase 1 301 8.9E-49 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 263 281 8.7E-24 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 286 306 8.7E-24 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 38 58 8.7E-24 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS19550 b7dfb17d16d0408f5cfd90cc0d5b8ac6 316 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 206 223 8.7E-24 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS22525 48c81e9a546a3da6859494729d5d57a0 133 SMART SM00342 24 107 2.4E-31 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS22525 48c81e9a546a3da6859494729d5d57a0 133 Pfam PF12833 Helix-turn-helix domain 30 109 1.7E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS22525 48c81e9a546a3da6859494729d5d57a0 133 SUPERFAMILY SSF46689 60 111 2.33E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS22525 48c81e9a546a3da6859494729d5d57a0 133 Gene3D G3DSA:1.10.10.60 7 62 2.4E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS22525 48c81e9a546a3da6859494729d5d57a0 133 SUPERFAMILY SSF46689 7 58 1.57E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS22525 48c81e9a546a3da6859494729d5d57a0 133 Gene3D G3DSA:1.10.10.60 63 112 1.5E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS29205 204ce681dcce2571cacc681f461a2c54 79 Pfam PF00550 Phosphopantetheine attachment site 13 73 2.4E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29205 204ce681dcce2571cacc681f461a2c54 79 SUPERFAMILY SSF47336 9 72 6.48E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29205 204ce681dcce2571cacc681f461a2c54 79 Gene3D G3DSA:1.10.1200.10 12 72 1.9E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS12965 75fcc9bd6bcf1cb55ed6289316cd5752 427 Gene3D G3DSA:3.50.50.60 10 177 2.3E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS12965 75fcc9bd6bcf1cb55ed6289316cd5752 427 SUPERFAMILY SSF51905 285 391 3.3E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS12965 75fcc9bd6bcf1cb55ed6289316cd5752 427 SUPERFAMILY SSF51905 11 182 3.3E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS12965 75fcc9bd6bcf1cb55ed6289316cd5752 427 Gene3D G3DSA:3.30.9.10 178 342 5.3E-51 T 06-07-2017 LK06_RS12965 75fcc9bd6bcf1cb55ed6289316cd5752 427 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 11 333 1.3E-88 T 06-07-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 LK06_RS12965 75fcc9bd6bcf1cb55ed6289316cd5752 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 2.8E-10 T 06-07-2017 LK06_RS12965 75fcc9bd6bcf1cb55ed6289316cd5752 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 2.8E-10 T 06-07-2017 LK06_RS12965 75fcc9bd6bcf1cb55ed6289316cd5752 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 2.8E-10 T 06-07-2017 LK06_RS12965 75fcc9bd6bcf1cb55ed6289316cd5752 427 Pfam PF01494 FAD binding domain 10 189 1.7E-13 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS04170 0a813b64cf798e4bab32910c2262a234 160 Gene3D G3DSA:3.40.50.300 1 156 7.1E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04170 0a813b64cf798e4bab32910c2262a234 160 Hamap MF_00109 Shikimate kinase [aroK]. 1 156 20.954 T 06-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 LK06_RS04170 0a813b64cf798e4bab32910c2262a234 160 Pfam PF01202 Shikimate kinase 1 155 5.3E-40 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 LK06_RS04170 0a813b64cf798e4bab32910c2262a234 160 ProSitePatterns PS01128 Shikimate kinase signature. 48 73 - T 06-07-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 LK06_RS04170 0a813b64cf798e4bab32910c2262a234 160 PRINTS PR01100 Shikimate kinase family signature 85 102 1.2E-5 T 06-07-2017 LK06_RS04170 0a813b64cf798e4bab32910c2262a234 160 PRINTS PR01100 Shikimate kinase family signature 47 55 1.2E-5 T 06-07-2017 LK06_RS04170 0a813b64cf798e4bab32910c2262a234 160 PRINTS PR01100 Shikimate kinase family signature 19 32 1.2E-5 T 06-07-2017 LK06_RS04170 0a813b64cf798e4bab32910c2262a234 160 PRINTS PR01100 Shikimate kinase family signature 65 74 1.2E-5 T 06-07-2017 LK06_RS04170 0a813b64cf798e4bab32910c2262a234 160 SUPERFAMILY SSF52540 1 155 1.26E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11165 c9772bad2ffdc79c051663c6bbe6f8b1 77 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 4 63 3.2E-16 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 LK06_RS11165 c9772bad2ffdc79c051663c6bbe6f8b1 77 SUPERFAMILY SSF55604 5 76 4.58E-20 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 LK06_RS11165 c9772bad2ffdc79c051663c6bbe6f8b1 77 Gene3D G3DSA:3.30.1360.60 3 77 3.2E-26 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 LK06_RS11165 c9772bad2ffdc79c051663c6bbe6f8b1 77 Pfam PF00367 phosphotransferase system, EIIB 7 39 3.3E-12 T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 LK06_RS12080 5aa7fa45f151a3496cfdc48d3daa0436 453 Gene3D G3DSA:3.20.20.140 64 386 2.1E-84 T 06-07-2017 LK06_RS12080 5aa7fa45f151a3496cfdc48d3daa0436 453 SUPERFAMILY SSF51338 335 445 1.91E-9 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS12080 5aa7fa45f151a3496cfdc48d3daa0436 453 Gene3D G3DSA:2.30.40.10 387 430 5.3E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS12080 5aa7fa45f151a3496cfdc48d3daa0436 453 Gene3D G3DSA:2.30.40.10 33 63 5.3E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS12080 5aa7fa45f151a3496cfdc48d3daa0436 453 Pfam PF01979 Amidohydrolase family 60 427 1.1E-46 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS12080 5aa7fa45f151a3496cfdc48d3daa0436 453 SUPERFAMILY SSF51556 61 375 1.17E-73 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS12080 5aa7fa45f151a3496cfdc48d3daa0436 453 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 4 452 1.7E-171 T 06-07-2017 IPR010252 Formiminoglutamate deiminase LK06_RS11605 0f3a3f454fa130eec7c420056818c1d0 595 Pfam PF00069 Protein kinase domain 55 283 2.2E-50 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS11605 0f3a3f454fa130eec7c420056818c1d0 595 Gene3D G3DSA:1.10.510.10 406 476 1.0E-53 T 06-07-2017 LK06_RS11605 0f3a3f454fa130eec7c420056818c1d0 595 Gene3D G3DSA:1.10.510.10 131 285 1.0E-53 T 06-07-2017 LK06_RS11605 0f3a3f454fa130eec7c420056818c1d0 595 SMART SM00220 8 290 4.1E-75 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS11605 0f3a3f454fa130eec7c420056818c1d0 595 Gene3D G3DSA:3.30.200.20 5 130 1.4E-21 T 06-07-2017 LK06_RS11605 0f3a3f454fa130eec7c420056818c1d0 595 SUPERFAMILY SSF56112 5 290 2.02E-79 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS11605 0f3a3f454fa130eec7c420056818c1d0 595 SUPERFAMILY SSF56112 431 507 2.02E-79 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS11605 0f3a3f454fa130eec7c420056818c1d0 595 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 152 164 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 Gene3D G3DSA:2.60.260.20 256 333 1.7E-21 T 06-07-2017 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 Pfam PF00684 DnaJ central domain 143 207 9.8E-13 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 Pfam PF01556 DnaJ C terminal domain 118 333 1.8E-39 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 PRINTS PR00625 DnaJ domain signature 24 39 3.9E-24 T 06-07-2017 IPR001623 DnaJ domain LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 PRINTS PR00625 DnaJ domain signature 40 60 3.9E-24 T 06-07-2017 IPR001623 DnaJ domain LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 PRINTS PR00625 DnaJ domain signature 60 79 3.9E-24 T 06-07-2017 IPR001623 DnaJ domain LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 PRINTS PR00625 DnaJ domain signature 6 24 3.9E-24 T 06-07-2017 IPR001623 DnaJ domain LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 Pfam PF00226 DnaJ domain 4 65 5.2E-26 T 06-07-2017 IPR001623 DnaJ domain LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 SUPERFAMILY SSF49493 213 256 8.76E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 SUPERFAMILY SSF49493 115 148 8.76E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 06-07-2017 IPR018253 DnaJ domain, conserved site LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 SMART SM00271 3 60 5.6E-31 T 06-07-2017 IPR001623 DnaJ domain LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 Gene3D G3DSA:2.60.260.20 210 253 1.2E-20 T 06-07-2017 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 Gene3D G3DSA:2.60.260.20 103 136 1.2E-20 T 06-07-2017 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 374 37.886 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 349 6.4E-120 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 SUPERFAMILY SSF46565 3 99 1.83E-32 T 06-07-2017 IPR001623 DnaJ domain LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 Gene3D G3DSA:2.10.230.10 137 209 5.2E-20 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 SUPERFAMILY SSF57938 130 210 1.28E-18 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 SUPERFAMILY SSF49493 258 344 1.57E-21 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 LK06_RS09495 5ed0ad44142aa3b95e805f135f0d54ec 378 Gene3D G3DSA:1.10.287.110 3 100 4.5E-33 T 06-07-2017 IPR001623 DnaJ domain LK06_RS08265 505f40e1e1b0597675999d292ef8891c 424 SUPERFAMILY SSF103473 18 397 1.22E-30 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08265 505f40e1e1b0597675999d292ef8891c 424 Gene3D G3DSA:1.20.1250.20 233 397 1.4E-11 T 06-07-2017 LK06_RS08265 505f40e1e1b0597675999d292ef8891c 424 Gene3D G3DSA:1.20.1250.20 21 199 5.7E-14 T 06-07-2017 LK06_RS08265 505f40e1e1b0597675999d292ef8891c 424 Pfam PF05977 Transmembrane secretion effector 10 407 6.2E-33 T 06-07-2017 IPR010290 Transmembrane secretion effector LK06_RS26550 d8e340cfb30d12f79a970276eac69658 368 Pfam PF13407 Periplasmic binding protein domain 47 305 2.0E-63 T 06-07-2017 IPR025997 Periplasmic binding protein LK06_RS26550 d8e340cfb30d12f79a970276eac69658 368 Gene3D G3DSA:3.40.50.2300 165 341 3.6E-42 T 06-07-2017 LK06_RS26550 d8e340cfb30d12f79a970276eac69658 368 SUPERFAMILY SSF53822 43 341 4.4E-64 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS26550 d8e340cfb30d12f79a970276eac69658 368 Gene3D G3DSA:3.40.50.2300 43 164 1.1E-24 T 06-07-2017 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PIRSF PIRSF000209 6 1058 0.0 T 06-07-2017 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 SUPERFAMILY SSF52218 492 642 9.01E-29 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 Pfam PF00258 Flavodoxin 502 624 8.3E-17 T 06-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 Pfam PF00667 FAD binding domain 675 878 4.7E-33 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 Gene3D G3DSA:1.10.630.10 14 463 1.7E-101 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 SUPERFAMILY SSF52343 900 1055 3.8E-34 T 06-07-2017 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PRINTS PR00463 E-class P450 group I signature 259 276 7.3E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PRINTS PR00463 E-class P450 group I signature 279 305 7.3E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PRINTS PR00463 E-class P450 group I signature 400 410 7.3E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PRINTS PR00463 E-class P450 group I signature 39 58 7.3E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PRINTS PR00463 E-class P450 group I signature 410 433 7.3E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PRINTS PR00463 E-class P450 group I signature 365 389 7.3E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 Gene3D G3DSA:3.40.50.80 909 1056 1.5E-41 T 06-07-2017 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 Gene3D G3DSA:3.40.50.360 497 642 1.6E-31 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 Pfam PF00067 Cytochrome P450 25 456 1.5E-69 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PRINTS PR00385 P450 superfamily signature 401 410 7.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PRINTS PR00385 P450 superfamily signature 325 336 7.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PRINTS PR00385 P450 superfamily signature 270 287 7.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 PRINTS PR00385 P450 superfamily signature 410 421 7.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 Pfam PF00175 Oxidoreductase NAD-binding domain 909 1019 2.2E-9 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 SUPERFAMILY SSF63380 674 894 5.88E-53 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 403 412 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 Gene3D G3DSA:1.20.990.10 711 835 5.8E-20 T 06-07-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 SUPERFAMILY SSF48264 14 461 2.49E-95 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 Gene3D G3DSA:2.40.30.10 675 710 7.6E-22 T 06-07-2017 LK06_RS01230 14e9f00f4415bd6e8dc94db6e96af3cb 1058 Gene3D G3DSA:2.40.30.10 836 908 7.6E-22 T 06-07-2017 LK06_RS02145 f0e0e70b44179c3b2fadd9cfcb0b1a62 272 Gene3D G3DSA:1.20.5.110 174 214 2.0E-18 T 06-07-2017 LK06_RS02145 f0e0e70b44179c3b2fadd9cfcb0b1a62 272 PRINTS PR00169 Potassium channel signature 182 208 1.3E-6 T 06-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 LK06_RS02145 f0e0e70b44179c3b2fadd9cfcb0b1a62 272 PRINTS PR00169 Potassium channel signature 153 175 1.3E-6 T 06-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 LK06_RS02145 f0e0e70b44179c3b2fadd9cfcb0b1a62 272 Gene3D G3DSA:1.10.287.70 126 172 3.1E-14 T 06-07-2017 LK06_RS02145 f0e0e70b44179c3b2fadd9cfcb0b1a62 272 SUPERFAMILY SSF81324 22 211 8.63E-29 T 06-07-2017 LK06_RS02145 f0e0e70b44179c3b2fadd9cfcb0b1a62 272 Pfam PF07885 Ion channel 134 209 6.5E-17 T 06-07-2017 IPR013099 Potassium channel domain LK06_RS26960 556acdfec8cb35766fcde1236d36db65 236 PIRSF PIRSF000857 1 236 1.1E-91 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 LK06_RS26960 556acdfec8cb35766fcde1236d36db65 236 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 30 235 4.3E-61 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 LK06_RS26960 556acdfec8cb35766fcde1236d36db65 236 Gene3D G3DSA:3.40.50.620 10 208 3.4E-57 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS26960 556acdfec8cb35766fcde1236d36db65 236 SUPERFAMILY SSF52402 20 197 1.54E-46 T 06-07-2017 LK06_RS26960 556acdfec8cb35766fcde1236d36db65 236 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 49 211 2.1E-42 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 LK06_RS25460 f5a3d48ee6023b1487bd3011e7f7cace 98 Pfam PF13834 Domain of unknown function (DUF4193) 1 97 4.4E-45 T 06-07-2017 IPR025242 Protein of unknown function DUF4193 LK06_RS29470 7b360b4ac782f19ac819cfe0f75eeb9b 327 SUPERFAMILY SSF51735 1 273 3.34E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29470 7b360b4ac782f19ac819cfe0f75eeb9b 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 222 1.7E-11 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS29470 7b360b4ac782f19ac819cfe0f75eeb9b 327 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 302 8.4E-64 T 06-07-2017 IPR010099 Epimerase family protein SDR39U1 LK06_RS29470 7b360b4ac782f19ac819cfe0f75eeb9b 327 Gene3D G3DSA:3.40.50.720 1 253 4.0E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29470 7b360b4ac782f19ac819cfe0f75eeb9b 327 Pfam PF08338 Domain of unknown function (DUF1731) 261 303 1.0E-9 T 06-07-2017 IPR013549 Domain of unknown function DUF1731 LK06_RS00555 245a83436abca00c3ed967a70b41ac0d 441 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 201 428 6.2E-22 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS00555 245a83436abca00c3ed967a70b41ac0d 441 SUPERFAMILY SSF52266 198 433 6.33E-42 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS00555 245a83436abca00c3ed967a70b41ac0d 441 Gene3D G3DSA:3.40.50.1110 197 434 9.0E-36 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS07080 c33b02ca136c4a2b131e8702e7c7d746 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 33.545 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 LK06_RS07080 c33b02ca136c4a2b131e8702e7c7d746 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 06-07-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 LK06_RS07080 c33b02ca136c4a2b131e8702e7c7d746 269 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 34 253 29.805 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 LK06_RS07080 c33b02ca136c4a2b131e8702e7c7d746 269 Gene3D G3DSA:3.20.20.70 2 259 5.1E-94 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS07080 c33b02ca136c4a2b131e8702e7c7d746 269 SUPERFAMILY SSF51366 12 257 7.06E-78 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 LK06_RS07080 c33b02ca136c4a2b131e8702e7c7d746 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 255 1.3E-79 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 88 2.2E-16 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 587 25.575 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 Gene3D G3DSA:3.40.50.620 115 464 1.9E-99 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 Pfam PF00750 tRNA synthetases class I (R) 113 457 8.2E-101 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 SUPERFAMILY SSF47323 466 587 2.03E-32 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 Pfam PF05746 DALR anticodon binding domain 472 587 2.2E-33 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 SUPERFAMILY SSF52374 113 464 2.74E-83 T 06-07-2017 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 SMART SM00836 472 587 1.2E-39 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 134 6.4E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 158 171 6.4E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 134 150 6.4E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 315 336 6.4E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 30 587 4.9E-133 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 SUPERFAMILY SSF55190 7 108 3.14E-16 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 SMART SM01016 9 89 1.8E-22 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 Gene3D G3DSA:3.30.1360.70 5 105 6.3E-25 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 127 138 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS13355 f742a06d777a414a5de5b26d275e89b0 587 Gene3D G3DSA:1.10.730.10 466 587 1.2E-34 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 SUPERFAMILY SSF49785 654 830 9.48E-31 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 Gene3D G3DSA:2.60.120.260 671 841 2.9E-49 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 Pfam PF13363 Beta-galactosidase, domain 3 580 644 2.8E-15 T 06-07-2017 IPR025972 Beta-galactosidase, domain 3 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 PRINTS PR00742 Glycosyl hydrolase family 35 signature 66 83 2.5E-27 T 06-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 PRINTS PR00742 Glycosyl hydrolase family 35 signature 912 928 2.5E-27 T 06-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 PRINTS PR00742 Glycosyl hydrolase family 35 signature 88 106 2.5E-27 T 06-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 PRINTS PR00742 Glycosyl hydrolase family 35 signature 143 162 2.5E-27 T 06-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 PRINTS PR00742 Glycosyl hydrolase family 35 signature 351 366 2.5E-27 T 06-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 PRINTS PR00742 Glycosyl hydrolase family 35 signature 198 213 2.5E-27 T 06-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 PRINTS PR00742 Glycosyl hydrolase family 35 signature 370 386 2.5E-27 T 06-07-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 Gene3D G3DSA:2.60.120.260 842 983 4.7E-44 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 SUPERFAMILY SSF49785 838 957 1.34E-38 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 SUPERFAMILY SSF117100 568 647 4.32E-17 T 06-07-2017 IPR025972 Beta-galactosidase, domain 3 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 Pfam PF01301 Glycosyl hydrolases family 35 62 400 1.5E-98 T 06-07-2017 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 SMART SM01029 410 576 1.3E-32 T 06-07-2017 IPR018954 Beta-galactosidase, domain 2 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 Gene3D G3DSA:2.102.20.10 417 568 2.5E-17 T 06-07-2017 IPR018954 Beta-galactosidase, domain 2 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 SUPERFAMILY SSF51445 53 403 1.06E-92 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 SUPERFAMILY SSF51011 420 542 1.94E-17 T 06-07-2017 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 Gene3D G3DSA:2.60.390.10 569 647 1.4E-17 T 06-07-2017 IPR025972 Beta-galactosidase, domain 3 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 Pfam PF13364 Beta-galactosidase jelly roll domain 677 800 1.2E-20 T 06-07-2017 IPR025300 Beta-galactosidase jelly roll domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024096|Reactome: R-HSA-2206308|Reactome: R-HSA-4085001 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 Pfam PF13364 Beta-galactosidase jelly roll domain 850 955 3.3E-31 T 06-07-2017 IPR025300 Beta-galactosidase jelly roll domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024096|Reactome: R-HSA-2206308|Reactome: R-HSA-4085001 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 Gene3D G3DSA:3.20.20.80 51 404 2.8E-105 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS08920 a01a80e1180566e0854b161aede59c7c 989 Pfam PF10435 Beta-galactosidase, domain 2 418 516 2.5E-8 T 06-07-2017 IPR018954 Beta-galactosidase, domain 2 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS12200 75d2e5b3ce5010e413ccbf1862aa3003 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 8.7E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase LK06_RS12200 75d2e5b3ce5010e413ccbf1862aa3003 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 8.7E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase LK06_RS12200 75d2e5b3ce5010e413ccbf1862aa3003 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 8.7E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase LK06_RS12200 75d2e5b3ce5010e413ccbf1862aa3003 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 8.7E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase LK06_RS12200 75d2e5b3ce5010e413ccbf1862aa3003 278 SUPERFAMILY SSF55920 3 256 5.76E-72 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS12200 75d2e5b3ce5010e413ccbf1862aa3003 278 Pfam PF00557 Metallopeptidase family M24 12 249 9.6E-42 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS12200 75d2e5b3ce5010e413ccbf1862aa3003 278 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 257 4.6E-80 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 LK06_RS12200 75d2e5b3ce5010e413ccbf1862aa3003 278 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 LK06_RS12200 75d2e5b3ce5010e413ccbf1862aa3003 278 Hamap MF_01974 Methionine aminopeptidase [map]. 2 258 37.373 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 LK06_RS12200 75d2e5b3ce5010e413ccbf1862aa3003 278 Gene3D G3DSA:3.90.230.10 4 258 1.7E-74 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS29520 97a273dbab41cb878c080a610da02cb2 690 SUPERFAMILY SSF49313 453 535 1.15E-13 T 06-07-2017 IPR015919 Cadherin-like GO:0005509|GO:0016020 LK06_RS29520 97a273dbab41cb878c080a610da02cb2 690 SUPERFAMILY SSF52743 113 442 1.7E-42 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS29520 97a273dbab41cb878c080a610da02cb2 690 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 368 378 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site LK06_RS29520 97a273dbab41cb878c080a610da02cb2 690 SUPERFAMILY SSF49785 545 686 1.49E-5 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS29520 97a273dbab41cb878c080a610da02cb2 690 Gene3D G3DSA:3.40.50.200 115 437 2.2E-62 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS29520 97a273dbab41cb878c080a610da02cb2 690 Gene3D G3DSA:2.60.40.10 454 534 6.5E-12 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS29520 97a273dbab41cb878c080a610da02cb2 690 SMART SM00736 451 540 1.4E-5 T 06-07-2017 IPR006644 Dystroglycan-type cadherin-like GO:0016020 LK06_RS29520 97a273dbab41cb878c080a610da02cb2 690 Pfam PF05345 Putative Ig domain 482 522 1.0E-11 T 06-07-2017 IPR008009 Putative Ig LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 Pfam PF12327 FtsZ family, C-terminal domain 219 313 4.5E-35 T 06-07-2017 IPR024757 Cell division protein FtsZ, C-terminal LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.1E-51 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.1E-51 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.1E-51 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.1E-51 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 4.1E-38 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 Gene3D G3DSA:3.30.1330.20 212 314 3.5E-49 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 315 2.4E-128 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 SUPERFAMILY SSF55307 201 315 5.95E-44 T 06-07-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 SMART SM00864 10 202 2.8E-110 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 SMART SM00865 204 321 3.0E-57 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 SUPERFAMILY SSF52490 9 205 8.9E-68 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 369 39.017 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 LK06_RS07290 a6b2c8e1dd08cd43d23bffbee7588716 404 Gene3D G3DSA:3.40.50.1440 11 211 3.6E-92 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LK06_RS06290 23fb97bbab5ab7c1351db301d67fa5ed 312 Pfam PF01903 CbiX 12 116 8.7E-27 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 LK06_RS06290 23fb97bbab5ab7c1351db301d67fa5ed 312 Pfam PF01903 CbiX 143 246 1.1E-23 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 LK06_RS06290 23fb97bbab5ab7c1351db301d67fa5ed 312 Gene3D G3DSA:3.40.50.1400 137 254 2.8E-27 T 06-07-2017 LK06_RS06290 23fb97bbab5ab7c1351db301d67fa5ed 312 Gene3D G3DSA:3.40.50.1400 6 124 2.3E-30 T 06-07-2017 LK06_RS06290 23fb97bbab5ab7c1351db301d67fa5ed 312 SUPERFAMILY SSF53800 5 253 8.39E-55 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 218 754 3.1E-156 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 Gene3D G3DSA:3.30.70.100 21 86 5.2E-23 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 Pfam PF00122 E1-E2 ATPase 227 445 3.2E-66 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 SUPERFAMILY SSF55008 19 90 3.8E-19 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 ProSitePatterns PS01047 Heavy-metal-associated domain. 28 56 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 456 462 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 228 732 3.6E-86 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 SUPERFAMILY SSF81653 260 354 6.93E-25 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 SUPERFAMILY SSF81665 224 258 7.85E-13 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 SUPERFAMILY SSF81665 355 448 7.85E-13 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 SUPERFAMILY SSF81665 700 724 7.85E-13 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 173 753 8.9E-184 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 Gene3D G3DSA:3.40.1110.10 470 578 1.1E-23 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 Gene3D G3DSA:2.70.150.10 220 355 1.0E-28 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 587 1.2E-24 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 651 670 1.2E-24 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 674 686 1.2E-24 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 304 318 1.2E-24 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 598 608 1.2E-24 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 454 468 1.2E-24 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00943 Copper-transporting ATPase signature 377 391 2.2E-8 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00943 Copper-transporting ATPase signature 65 85 2.2E-8 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00943 Copper-transporting ATPase signature 437 452 2.2E-8 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00943 Copper-transporting ATPase signature 628 645 2.2E-8 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00943 Copper-transporting ATPase signature 224 243 2.2E-8 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 PRINTS PR00943 Copper-transporting ATPase signature 244 262 2.2E-8 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 Pfam PF00403 Heavy-metal-associated domain 27 84 7.3E-14 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 ProSitePatterns PS01229 Hypothetical cof family signature 2. 651 673 - T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 Gene3D G3DSA:3.40.50.1000 425 469 1.4E-52 T 06-07-2017 IPR023214 HAD-like domain LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 Gene3D G3DSA:3.40.50.1000 579 719 1.4E-52 T 06-07-2017 IPR023214 HAD-like domain LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 Pfam PF00702 haloacid dehalogenase-like hydrolase 450 665 4.2E-47 T 06-07-2017 LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 SUPERFAMILY SSF56784 452 472 9.51E-56 T 06-07-2017 IPR023214 HAD-like domain LK06_RS10605 ab9fed5c0d3184341474812573c33e3d 757 SUPERFAMILY SSF56784 511 751 9.51E-56 T 06-07-2017 IPR023214 HAD-like domain LK06_RS17810 d07fa402780c72058628e069c4868128 422 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 91 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LK06_RS17810 d07fa402780c72058628e069c4868128 422 Gene3D G3DSA:1.20.1250.20 216 407 6.3E-23 T 06-07-2017 LK06_RS17810 d07fa402780c72058628e069c4868128 422 SUPERFAMILY SSF103473 19 399 3.92E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS17810 d07fa402780c72058628e069c4868128 422 Pfam PF07690 Major Facilitator Superfamily 26 252 5.0E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS17810 d07fa402780c72058628e069c4868128 422 Gene3D G3DSA:1.20.1250.20 21 199 3.3E-28 T 06-07-2017 LK06_RS24060 a594619f03fcd2185bfa4ca4c59720f5 536 Pfam PF08502 LeuA allosteric (dimerisation) domain 384 525 4.9E-28 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS24060 a594619f03fcd2185bfa4ca4c59720f5 536 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 13 529 1.5E-192 T 06-07-2017 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 LK06_RS24060 a594619f03fcd2185bfa4ca4c59720f5 536 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 20 36 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS24060 a594619f03fcd2185bfa4ca4c59720f5 536 Gene3D G3DSA:3.20.20.70 6 357 5.4E-115 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS24060 a594619f03fcd2185bfa4ca4c59720f5 536 SUPERFAMILY SSF51569 9 301 3.85E-78 T 06-07-2017 LK06_RS24060 a594619f03fcd2185bfa4ca4c59720f5 536 SMART SM00917 384 527 3.1E-37 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS24060 a594619f03fcd2185bfa4ca4c59720f5 536 SUPERFAMILY SSF110921 407 522 3.01E-21 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS24060 a594619f03fcd2185bfa4ca4c59720f5 536 Pfam PF00682 HMGL-like 14 279 1.0E-47 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Pfam PF13745 HxxPF-repeated domain 939 1034 3.0E-30 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Pfam PF00668 Condensation domain 618 917 1.0E-61 T 06-07-2017 IPR001242 Condensation domain LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Pfam PF00501 AMP-binding enzyme 31 426 4.3E-94 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Pfam PF00501 AMP-binding enzyme 1088 1481 1.8E-96 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 SMART SM00823 Phosphopantetheine attachment site 1587 1656 7.2E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 SMART SM00823 Phosphopantetheine attachment site 534 603 1.6E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1236 1247 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 SUPERFAMILY SSF47336 1584 1652 6.67E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Pfam PF13193 AMP-binding enzyme C-terminal domain 435 510 3.5E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Pfam PF13193 AMP-binding enzyme C-terminal domain 1489 1564 5.1E-13 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 SUPERFAMILY SSF47336 527 600 1.26E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Gene3D G3DSA:3.40.50.980 1083 1245 1.5E-47 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Gene3D G3DSA:3.40.50.980 26 190 4.3E-51 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 SUPERFAMILY SSF52777 620 792 1.67E-51 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Gene3D G3DSA:3.30.300.30 1476 1594 1.3E-37 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Gene3D G3DSA:3.30.300.30 422 537 2.4E-37 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Gene3D G3DSA:3.40.50.980 191 340 1.8E-30 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Gene3D G3DSA:3.40.50.980 1246 1393 2.4E-35 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Pfam PF00550 Phosphopantetheine attachment site 1589 1652 8.9E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Pfam PF00550 Phosphopantetheine attachment site 537 597 6.2E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 SUPERFAMILY SSF52777 805 1071 7.34E-60 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Gene3D G3DSA:2.30.38.10 341 416 1.3E-27 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Gene3D G3DSA:2.30.38.10 1394 1470 1.2E-28 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 52 451 8.1E-126 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1109 1505 1.3E-127 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 SUPERFAMILY SSF56801 1047 1600 1.13E-157 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 SUPERFAMILY SSF56801 12 547 1.44E-153 T 06-07-2017 LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 ProSitePatterns PS00012 Phosphopantetheine attachment site. 558 573 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Gene3D G3DSA:1.10.1200.10 538 603 5.7E-27 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02690 6390c6754859f25ae77d4781db68e6e6 1673 Gene3D G3DSA:1.10.1200.10 1595 1654 8.1E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS18985 71e34b382806c72e4a3f30cd7d4c48c6 576 SUPERFAMILY SSF51556 363 496 1.0E-54 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS18985 71e34b382806c72e4a3f30cd7d4c48c6 576 SUPERFAMILY SSF51556 55 312 1.0E-54 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS18985 71e34b382806c72e4a3f30cd7d4c48c6 576 Gene3D G3DSA:2.30.40.10 483 565 1.7E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS18985 71e34b382806c72e4a3f30cd7d4c48c6 576 Gene3D G3DSA:2.30.40.10 1 54 3.0E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS18985 71e34b382806c72e4a3f30cd7d4c48c6 576 Gene3D G3DSA:3.20.20.140 421 482 1.1E-78 T 06-07-2017 LK06_RS18985 71e34b382806c72e4a3f30cd7d4c48c6 576 Gene3D G3DSA:3.20.20.140 55 304 1.1E-78 T 06-07-2017 LK06_RS18985 71e34b382806c72e4a3f30cd7d4c48c6 576 SUPERFAMILY SSF51338 1 54 2.97E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS18985 71e34b382806c72e4a3f30cd7d4c48c6 576 SUPERFAMILY SSF51338 496 560 2.97E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS18985 71e34b382806c72e4a3f30cd7d4c48c6 576 Pfam PF07969 Amidohydrolase family 45 547 1.3E-67 T 06-07-2017 IPR013108 Amidohydrolase 3 LK06_RS20355 bf32a9fe9e5140318a24494acc499b2e 212 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 12 200 29.764 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 LK06_RS20355 bf32a9fe9e5140318a24494acc499b2e 212 Pfam PF00551 Formyl transferase 11 194 1.4E-52 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS20355 bf32a9fe9e5140318a24494acc499b2e 212 Gene3D G3DSA:3.40.50.170 11 207 2.6E-69 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS20355 bf32a9fe9e5140318a24494acc499b2e 212 SUPERFAMILY SSF53328 11 210 5.63E-58 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS20355 bf32a9fe9e5140318a24494acc499b2e 212 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 146 169 - T 06-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS20355 bf32a9fe9e5140318a24494acc499b2e 212 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 11 203 9.2E-67 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 SUPERFAMILY SSF49493 138 192 5.76E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 SUPERFAMILY SSF49493 237 288 5.76E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 SMART SM00271 9 67 7.0E-30 T 06-07-2017 IPR001623 DnaJ domain LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 Gene3D G3DSA:2.60.260.20 234 277 3.2E-22 T 06-07-2017 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 Gene3D G3DSA:2.60.260.20 126 165 3.2E-22 T 06-07-2017 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 PRINTS PR00625 DnaJ domain signature 12 30 3.2E-23 T 06-07-2017 IPR001623 DnaJ domain LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 PRINTS PR00625 DnaJ domain signature 47 67 3.2E-23 T 06-07-2017 IPR001623 DnaJ domain LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 PRINTS PR00625 DnaJ domain signature 67 86 3.2E-23 T 06-07-2017 IPR001623 DnaJ domain LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 PRINTS PR00625 DnaJ domain signature 30 45 3.2E-23 T 06-07-2017 IPR001623 DnaJ domain LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 SUPERFAMILY SSF46565 9 108 1.57E-30 T 06-07-2017 IPR001623 DnaJ domain LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 Gene3D G3DSA:2.60.260.20 280 358 8.3E-21 T 06-07-2017 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 Pfam PF01556 DnaJ C terminal domain 144 357 2.5E-35 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 Pfam PF00684 DnaJ central domain 171 231 3.1E-10 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 Gene3D G3DSA:1.10.287.110 4 98 1.7E-31 T 06-07-2017 IPR001623 DnaJ domain LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 06-07-2017 IPR018253 DnaJ domain, conserved site LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 SUPERFAMILY SSF49493 283 368 3.4E-20 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 391 37.54 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 SUPERFAMILY SSF57938 158 233 3.92E-14 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 Gene3D G3DSA:2.10.230.10 166 233 2.7E-16 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 Pfam PF00226 DnaJ domain 10 72 7.9E-27 T 06-07-2017 IPR001623 DnaJ domain LK06_RS14750 7c5d74d6c419eb2f1e7a31cdc431004a 391 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 374 3.8E-123 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 SUPERFAMILY SSF51735 311 577 4.44E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 445 453 1.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 391 402 1.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 465 484 1.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 316 333 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 486 503 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 439 455 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 391 402 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 465 484 1.7E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 Gene3D G3DSA:3.40.50.720 314 549 3.4E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 Pfam PF00106 short chain dehydrogenase 316 506 9.4E-54 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 Pfam PF00561 alpha/beta hydrolase fold 27 143 5.3E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 Gene3D G3DSA:3.40.50.1820 4 292 2.2E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 SUPERFAMILY SSF53474 4 292 1.15E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 315 496 0.0074 T 06-07-2017 LK06_RS16190 265d2150c4f3ac8c0a26879525b5ab09 582 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 452 480 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS29985 9dc1aee2d5cd5a7ab2011414bc537c0f 170 SUPERFAMILY SSF56281 9 92 2.61E-11 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS29985 9dc1aee2d5cd5a7ab2011414bc537c0f 170 Gene3D G3DSA:3.60.15.10 4 92 3.7E-11 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 SUPERFAMILY SSF54631 434 555 8.49E-16 T 06-07-2017 LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 SMART SM00116 507 556 100.0 T 06-07-2017 IPR000644 CBS domain LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 SMART SM00116 443 491 0.014 T 06-07-2017 IPR000644 CBS domain LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 Gene3D G3DSA:3.10.580.10 435 555 9.5E-16 T 06-07-2017 LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 Gene3D G3DSA:1.10.3080.10 2 421 3.8E-91 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 PRINTS PR00762 Chloride channel signature 74 91 2.5E-26 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 PRINTS PR00762 Chloride channel signature 353 369 2.5E-26 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 PRINTS PR00762 Chloride channel signature 154 173 2.5E-26 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 PRINTS PR00762 Chloride channel signature 318 338 2.5E-26 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 PRINTS PR00762 Chloride channel signature 371 390 2.5E-26 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 Pfam PF00654 Voltage gated chloride channel 60 403 3.3E-94 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 Pfam PF00571 CBS domain 436 491 8.5E-8 T 06-07-2017 IPR000644 CBS domain LK06_RS00505 77fe6e14bfa0ebd71a3a120b9effcc3b 560 SUPERFAMILY SSF81340 2 422 3.01E-108 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 LK06_RS30555 bc79af33c53937c79a9f2acf0ec1fd21 520 Gene3D G3DSA:3.30.300.30 411 512 7.9E-30 T 06-07-2017 LK06_RS30555 bc79af33c53937c79a9f2acf0ec1fd21 520 Gene3D G3DSA:3.40.50.980 10 178 6.7E-29 T 06-07-2017 LK06_RS30555 bc79af33c53937c79a9f2acf0ec1fd21 520 SUPERFAMILY SSF56801 7 514 1.7E-118 T 06-07-2017 LK06_RS30555 bc79af33c53937c79a9f2acf0ec1fd21 520 Gene3D G3DSA:3.40.50.980 205 321 1.4E-27 T 06-07-2017 LK06_RS30555 bc79af33c53937c79a9f2acf0ec1fd21 520 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 502 8.8E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS30555 bc79af33c53937c79a9f2acf0ec1fd21 520 Gene3D G3DSA:2.30.38.10 332 405 2.1E-11 T 06-07-2017 LK06_RS30555 bc79af33c53937c79a9f2acf0ec1fd21 520 Pfam PF00501 AMP-binding enzyme 12 415 2.5E-65 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS15965 cc5d21c9cbfab4cb1702086b003c7206 892 Pfam PF00912 Transglycosylase 185 363 4.2E-57 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 LK06_RS15965 cc5d21c9cbfab4cb1702086b003c7206 892 SUPERFAMILY SSF53955 168 380 2.73E-65 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS15965 cc5d21c9cbfab4cb1702086b003c7206 892 SUPERFAMILY SSF56601 347 367 1.38E-73 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS15965 cc5d21c9cbfab4cb1702086b003c7206 892 SUPERFAMILY SSF56601 398 776 1.38E-73 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS15965 cc5d21c9cbfab4cb1702086b003c7206 892 Gene3D G3DSA:3.40.710.10 367 812 9.5E-92 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS15965 cc5d21c9cbfab4cb1702086b003c7206 892 Pfam PF00905 Penicillin binding protein transpeptidase domain 469 731 1.2E-20 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS15965 cc5d21c9cbfab4cb1702086b003c7206 892 Gene3D G3DSA:1.10.3810.10 180 366 2.5E-65 T 06-07-2017 LK06_RS06940 69ae47bb1788c63312c4bf9eb27c10a7 473 Gene3D G3DSA:3.50.50.60 218 362 1.8E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS06940 69ae47bb1788c63312c4bf9eb27c10a7 473 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 16 359 2.7E-113 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase LK06_RS06940 69ae47bb1788c63312c4bf9eb27c10a7 473 SUPERFAMILY SSF51905 210 371 2.04E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS06940 69ae47bb1788c63312c4bf9eb27c10a7 473 SUPERFAMILY SSF51905 14 267 2.46E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS06940 69ae47bb1788c63312c4bf9eb27c10a7 473 Gene3D G3DSA:3.50.50.60 100 217 8.6E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS14945 8338f25f3b2faddff2f78afe8b3b6a29 314 SUPERFAMILY SSF88946 11 90 3.69E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14945 8338f25f3b2faddff2f78afe8b3b6a29 314 SUPERFAMILY SSF54427 172 294 2.75E-10 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS14945 8338f25f3b2faddff2f78afe8b3b6a29 314 Gene3D G3DSA:1.10.10.10 111 163 7.8E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14945 8338f25f3b2faddff2f78afe8b3b6a29 314 Pfam PF04542 Sigma-70 region 2 12 74 5.0E-15 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14945 8338f25f3b2faddff2f78afe8b3b6a29 314 SUPERFAMILY SSF88659 86 162 1.12E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14945 8338f25f3b2faddff2f78afe8b3b6a29 314 Gene3D G3DSA:1.10.1740.10 11 76 2.8E-13 T 06-07-2017 LK06_RS14945 8338f25f3b2faddff2f78afe8b3b6a29 314 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 162 2.7E-16 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14945 8338f25f3b2faddff2f78afe8b3b6a29 314 Pfam PF08281 Sigma-70, region 4 111 161 3.3E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14945 8338f25f3b2faddff2f78afe8b3b6a29 314 Gene3D G3DSA:3.10.450.50 171 294 2.0E-9 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 SUPERFAMILY SSF54292 244 360 1.31E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 Gene3D G3DSA:2.40.30.10 9 104 3.7E-17 T 06-07-2017 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 Pfam PF00175 Oxidoreductase NAD-binding domain 124 234 1.3E-15 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 Gene3D G3DSA:3.40.50.80 105 246 3.6E-34 T 06-07-2017 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 283 351 2.1E-12 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 Pfam PF00970 Oxidoreductase FAD-binding domain 15 112 5.4E-8 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 SUPERFAMILY SSF52343 103 250 7.46E-31 T 06-07-2017 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 PRINTS PR00406 Cytochrome B5 reductase signature 123 142 2.5E-5 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 PRINTS PR00406 Cytochrome B5 reductase signature 220 228 2.5E-5 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 PRINTS PR00406 Cytochrome B5 reductase signature 100 114 2.5E-5 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 SUPERFAMILY SSF63380 8 114 2.69E-17 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 309 317 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LK06_RS31485 3f9c4df30b0c6022375f1ab80695b8b0 362 Gene3D G3DSA:3.10.20.30 247 359 2.2E-24 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS22520 25a60ae29223b7a2b96d469271bc2d9f 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 4.5E-13 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS22520 25a60ae29223b7a2b96d469271bc2d9f 138 Gene3D G3DSA:3.10.180.10 1 134 1.7E-30 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS22520 25a60ae29223b7a2b96d469271bc2d9f 138 SUPERFAMILY SSF54593 3 135 1.02E-25 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS09335 354bf737cfe4593355ba2d2b8835207a 308 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 168 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS09335 354bf737cfe4593355ba2d2b8835207a 308 SUPERFAMILY SSF51569 2 306 7.85E-72 T 06-07-2017 LK06_RS09335 354bf737cfe4593355ba2d2b8835207a 308 Pfam PF00701 Dihydrodipicolinate synthetase family 7 302 3.3E-44 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS09335 354bf737cfe4593355ba2d2b8835207a 308 PIRSF PIRSF001365 2 308 8.4E-73 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS09335 354bf737cfe4593355ba2d2b8835207a 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 1.3E-7 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS09335 354bf737cfe4593355ba2d2b8835207a 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 1.3E-7 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS09335 354bf737cfe4593355ba2d2b8835207a 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 1.3E-7 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS09335 354bf737cfe4593355ba2d2b8835207a 308 SMART SM01130 6 306 1.3E-73 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS09335 354bf737cfe4593355ba2d2b8835207a 308 Gene3D G3DSA:3.20.20.70 6 307 3.0E-79 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS20100 1555221b6c9ced973bf3744eace6bd11 425 Pfam PF09445 RNA cap guanine-N2 methyltransferase 135 192 7.2E-7 T 06-07-2017 IPR019012 RNA cap guanine-N2 methyltransferase GO:0001510|GO:0008168|GO:0009452 Reactome: R-HSA-1368082|Reactome: R-HSA-1368108|Reactome: R-HSA-191859|Reactome: R-HSA-1989781|Reactome: R-HSA-2032785|Reactome: R-HSA-2151201|Reactome: R-HSA-2426168|Reactome: R-HSA-381340|Reactome: R-HSA-400206|Reactome: R-HSA-400253 LK06_RS20100 1555221b6c9ced973bf3744eace6bd11 425 SUPERFAMILY SSF53335 97 260 3.7E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS20100 1555221b6c9ced973bf3744eace6bd11 425 Gene3D G3DSA:3.40.50.150 110 206 4.2E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS14260 f8f693eb8244822755f01bc2852abb35 141 Gene3D G3DSA:3.40.50.1010 16 130 1.2E-6 T 06-07-2017 IPR029060 PIN domain-like LK06_RS14260 f8f693eb8244822755f01bc2852abb35 141 SUPERFAMILY SSF88723 15 131 9.81E-12 T 06-07-2017 IPR029060 PIN domain-like LK06_RS14260 f8f693eb8244822755f01bc2852abb35 141 Pfam PF01850 PIN domain 17 126 1.2E-5 T 06-07-2017 IPR002716 PIN domain LK06_RS17705 0cfdff57bcaf2c49b0c0a7d5cccb2415 266 SUPERFAMILY SSF56784 39 260 1.16E-27 T 06-07-2017 IPR023214 HAD-like domain LK06_RS17705 0cfdff57bcaf2c49b0c0a7d5cccb2415 266 Pfam PF13419 Haloacid dehalogenase-like hydrolase 142 229 6.0E-12 T 06-07-2017 IPR023214 HAD-like domain LK06_RS17705 0cfdff57bcaf2c49b0c0a7d5cccb2415 266 Gene3D G3DSA:3.40.50.1000 27 61 8.9E-25 T 06-07-2017 IPR023214 HAD-like domain LK06_RS17705 0cfdff57bcaf2c49b0c0a7d5cccb2415 266 Gene3D G3DSA:3.40.50.1000 123 259 8.9E-25 T 06-07-2017 IPR023214 HAD-like domain LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 SUPERFAMILY SSF53448 269 325 1.39E-79 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 SUPERFAMILY SSF53448 1 237 1.39E-79 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 384 511 8.8E-15 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 SUPERFAMILY SSF53738 637 741 7.46E-12 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 SUPERFAMILY SSF55957 744 828 2.09E-11 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Pfam PF00483 Nucleotidyl transferase 2 233 4.4E-53 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 532 632 6.7E-18 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Gene3D G3DSA:2.160.10.10 240 366 7.7E-27 T 06-07-2017 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Gene3D G3DSA:3.30.310.50 752 828 2.1E-10 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 258 283 5.5E-4 T 06-07-2017 IPR001451 Hexapeptide repeat LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 SUPERFAMILY SSF53738 530 634 1.22E-13 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 SUPERFAMILY SSF51161 235 433 4.42E-33 T 06-07-2017 IPR011004 Trimeric LpxA-like LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 639 740 1.6E-5 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Gene3D G3DSA:3.90.550.10 1 236 1.7E-75 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Gene3D G3DSA:3.40.120.10 384 511 5.6E-14 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Gene3D G3DSA:3.40.120.10 552 628 4.0E-12 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS03660 846063ffcbdfd49bd2ca5e8575e35e03 831 Gene3D G3DSA:3.40.120.10 629 744 7.7E-13 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS08100 9658572f8a0982e92ce3d70216dbdb3f 560 Gene3D G3DSA:3.90.400.10 124 201 4.7E-30 T 06-07-2017 LK06_RS08100 9658572f8a0982e92ce3d70216dbdb3f 560 SMART SM00642 32 428 3.0E-131 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS08100 9658572f8a0982e92ce3d70216dbdb3f 560 Pfam PF00128 Alpha amylase, catalytic domain 47 405 8.1E-81 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS08100 9658572f8a0982e92ce3d70216dbdb3f 560 Pfam PF11941 Domain of unknown function (DUF3459) 477 557 9.7E-8 T 06-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) LK06_RS08100 9658572f8a0982e92ce3d70216dbdb3f 560 SUPERFAMILY SSF51445 22 491 1.83E-130 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS08100 9658572f8a0982e92ce3d70216dbdb3f 560 Gene3D G3DSA:3.20.20.80 202 493 2.2E-110 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS08100 9658572f8a0982e92ce3d70216dbdb3f 560 Gene3D G3DSA:3.20.20.80 22 123 2.2E-110 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS02025 eea8e61822fdb89bc04860343ca91f97 329 Pfam PF00535 Glycosyl transferase family 2 8 159 3.4E-17 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS02025 eea8e61822fdb89bc04860343ca91f97 329 Gene3D G3DSA:3.90.550.10 2 134 1.5E-10 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS02025 eea8e61822fdb89bc04860343ca91f97 329 SUPERFAMILY SSF53448 2 242 1.36E-25 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS31175 c5f386012436f3585e4f22e93cc9efd0 281 Pfam PF01374 Glycosyl hydrolase family 46 60 269 1.5E-99 T 06-07-2017 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 LK06_RS31175 c5f386012436f3585e4f22e93cc9efd0 281 PIRSF PIRSF036551 4 281 7.1E-107 T 06-07-2017 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 LK06_RS31175 c5f386012436f3585e4f22e93cc9efd0 281 Gene3D G3DSA:1.20.141.10 156 281 6.4E-67 T 06-07-2017 LK06_RS31175 c5f386012436f3585e4f22e93cc9efd0 281 ProSitePatterns PS60000 Chitosanases families 46 and 80 active sites signature. 66 104 - T 06-07-2017 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 LK06_RS31175 c5f386012436f3585e4f22e93cc9efd0 281 Gene3D G3DSA:3.30.386.10 44 155 9.7E-55 T 06-07-2017 IPR023099 Glycoside hydrolase, family 46, N-terminal GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 LK06_RS31175 c5f386012436f3585e4f22e93cc9efd0 281 SUPERFAMILY SSF53955 46 280 1.21E-91 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS30375 4c5ccd5091e1fa3f365249de7fae595d 387 Pfam PF07497 Rho termination factor, RNA-binding domain 21 79 1.1E-8 T 06-07-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 LK06_RS30375 4c5ccd5091e1fa3f365249de7fae595d 387 Gene3D G3DSA:3.40.50.300 94 375 2.8E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30375 4c5ccd5091e1fa3f365249de7fae595d 387 Gene3D G3DSA:2.40.50.140 19 72 1.0E-11 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS30375 4c5ccd5091e1fa3f365249de7fae595d 387 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 118 319 2.6E-16 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS30375 4c5ccd5091e1fa3f365249de7fae595d 387 SUPERFAMILY SSF52540 90 329 2.78E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30375 4c5ccd5091e1fa3f365249de7fae595d 387 SUPERFAMILY SSF50249 20 85 1.22E-6 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS30375 4c5ccd5091e1fa3f365249de7fae595d 387 SMART SM00382 128 319 5.2E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS30375 4c5ccd5091e1fa3f365249de7fae595d 387 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 378 148.338 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 LK06_RS18280 810b8b096307f1d45ae73e16bb3c50f3 314 Gene3D G3DSA:3.90.550.10 35 164 2.2E-11 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS18280 810b8b096307f1d45ae73e16bb3c50f3 314 SUPERFAMILY SSF53448 35 269 7.5E-59 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS18280 810b8b096307f1d45ae73e16bb3c50f3 314 Pfam PF00535 Glycosyl transferase family 2 36 152 1.4E-9 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS08895 681920f23ceb6dea77f97e266320b3fc 139 Pfam PF02566 OsmC-like protein 43 138 5.9E-18 T 06-07-2017 IPR003718 OsmC/Ohr family LK06_RS08895 681920f23ceb6dea77f97e266320b3fc 139 Gene3D G3DSA:2.20.25.10 6 49 4.9E-20 T 06-07-2017 LK06_RS08895 681920f23ceb6dea77f97e266320b3fc 139 SUPERFAMILY SSF82784 3 138 5.5E-43 T 06-07-2017 IPR003718 OsmC/Ohr family LK06_RS08895 681920f23ceb6dea77f97e266320b3fc 139 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 9 138 1.2E-52 T 06-07-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 LK06_RS08895 681920f23ceb6dea77f97e266320b3fc 139 Gene3D G3DSA:3.30.300.20 50 138 6.4E-35 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS07855 8175a7ac9c87b2e62accd59f594c2955 265 Gene3D G3DSA:3.90.1550.10 179 250 7.9E-76 T 06-07-2017 LK06_RS07855 8175a7ac9c87b2e62accd59f594c2955 265 Gene3D G3DSA:3.90.1550.10 14 136 7.9E-76 T 06-07-2017 LK06_RS07855 8175a7ac9c87b2e62accd59f594c2955 265 SUPERFAMILY SSF55681 14 132 6.05E-60 T 06-07-2017 LK06_RS07855 8175a7ac9c87b2e62accd59f594c2955 265 SUPERFAMILY SSF55681 178 251 6.05E-60 T 06-07-2017 LK06_RS07855 8175a7ac9c87b2e62accd59f594c2955 265 Hamap MF_00013 Octanoyltransferase [lipB]. 3 253 32.696 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LK06_RS07855 8175a7ac9c87b2e62accd59f594c2955 265 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 77 129 6.0E-23 T 06-07-2017 LK06_RS07855 8175a7ac9c87b2e62accd59f594c2955 265 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 73 88 - T 06-07-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 LK06_RS07855 8175a7ac9c87b2e62accd59f594c2955 265 PIRSF PIRSF016262 3 262 4.3E-58 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 Gene3D G3DSA:3.30.450.40 630 811 1.5E-33 T 06-07-2017 IPR029016 GAF domain-like LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 36 443 7.4E-78 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 SMART SM00331 834 1061 2.7E-34 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 SMART SM00065 624 813 5.2E-6 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 8 490 5.1E-172 T 06-07-2017 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 SUPERFAMILY SSF55874 1105 1185 4.95E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 SUPERFAMILY SSF55781 709 816 1.66E-12 T 06-07-2017 IPR029016 GAF domain-like LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 SUPERFAMILY SSF55785 516 626 2.97E-9 T 06-07-2017 IPR000014 PAS domain LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 Pfam PF13581 Histidine kinase-like ATPase domain 1074 1181 3.1E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 Pfam PF00474 Sodium:solute symporter family 36 443 6.6E-86 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 Pfam PF08448 PAS fold 510 619 9.3E-16 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 861 1061 6.5E-48 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 Gene3D G3DSA:3.30.450.20 496 629 2.4E-13 T 06-07-2017 LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 Pfam PF01590 GAF domain 644 802 2.3E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS15050 420e6244bd8b3f9e5143bb6311199900 1192 SUPERFAMILY SSF81606 850 1060 1.02E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS24470 b521e8b0e246187e40c29de25b638164 541 Gene3D G3DSA:3.40.50.300 214 415 2.1E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24470 b521e8b0e246187e40c29de25b638164 541 Pfam PF01078 Magnesium chelatase, subunit ChlI 215 421 9.0E-87 T 06-07-2017 IPR000523 Magnesium chelatase ChlI domain LK06_RS24470 b521e8b0e246187e40c29de25b638164 541 Gene3D G3DSA:3.30.230.10 7 168 5.7E-37 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS24470 b521e8b0e246187e40c29de25b638164 541 SUPERFAMILY SSF52540 489 526 2.48E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24470 b521e8b0e246187e40c29de25b638164 541 SUPERFAMILY SSF52540 212 456 2.48E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24470 b521e8b0e246187e40c29de25b638164 541 SUPERFAMILY SSF54211 2 170 2.58E-36 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS24470 b521e8b0e246187e40c29de25b638164 541 SMART SM00382 235 419 3.9E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS24470 b521e8b0e246187e40c29de25b638164 541 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 430 526 1.1E-20 T 06-07-2017 IPR025158 Mg chelatase-related protein, C-terminal domain LK06_RS24470 b521e8b0e246187e40c29de25b638164 541 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 141 5.4E-38 T 06-07-2017 LK06_RS04900 1c799d363588426df89d04f970e57ca2 190 SUPERFAMILY SSF51182 55 176 1.1E-13 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS04900 1c799d363588426df89d04f970e57ca2 190 SMART SM00530 15 70 2.5E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS04900 1c799d363588426df89d04f970e57ca2 190 Pfam PF07883 Cupin domain 117 170 1.2E-8 T 06-07-2017 IPR013096 Cupin 2, conserved barrel LK06_RS04900 1c799d363588426df89d04f970e57ca2 190 Gene3D G3DSA:1.10.260.40 12 91 9.7E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS04900 1c799d363588426df89d04f970e57ca2 190 SUPERFAMILY SSF47413 8 75 2.03E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS04900 1c799d363588426df89d04f970e57ca2 190 Gene3D G3DSA:2.60.120.10 97 178 3.6E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS04900 1c799d363588426df89d04f970e57ca2 190 Pfam PF13560 Helix-turn-helix domain 12 71 4.6E-12 T 06-07-2017 LK06_RS22795 487ed5d111bdb6c1e7f6943cdcd81d21 390 Pfam PF02735 Ku70/Ku80 beta-barrel domain 14 181 1.3E-31 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 LK06_RS22795 487ed5d111bdb6c1e7f6943cdcd81d21 390 Gene3D G3DSA:2.40.290.10 7 150 1.0E-9 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain LK06_RS22795 487ed5d111bdb6c1e7f6943cdcd81d21 390 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 4 255 29.834 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type LK06_RS22795 487ed5d111bdb6c1e7f6943cdcd81d21 390 TIGRFAM TIGR02772 Ku_bact: Ku protein 4 257 2.1E-86 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type LK06_RS22795 487ed5d111bdb6c1e7f6943cdcd81d21 390 SUPERFAMILY SSF100939 5 256 4.32E-43 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain LK06_RS22795 487ed5d111bdb6c1e7f6943cdcd81d21 390 SMART SM00559 55 184 1.0E-41 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 LK06_RS13670 737e02c6572a07ef038f6434abaaca0f 177 SUPERFAMILY SSF55729 13 139 2.36E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS13670 737e02c6572a07ef038f6434abaaca0f 177 Pfam PF00583 Acetyltransferase (GNAT) family 61 130 5.4E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS13670 737e02c6572a07ef038f6434abaaca0f 177 Gene3D G3DSA:3.40.630.30 12 155 1.6E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS08810 acd6b844cb4be588c5813cd27fc881ba 208 Gene3D G3DSA:1.10.357.10 60 201 1.0E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS08810 acd6b844cb4be588c5813cd27fc881ba 208 Gene3D G3DSA:1.10.10.60 4 59 9.1E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS08810 acd6b844cb4be588c5813cd27fc881ba 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.7E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS08810 acd6b844cb4be588c5813cd27fc881ba 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS08810 acd6b844cb4be588c5813cd27fc881ba 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS08810 acd6b844cb4be588c5813cd27fc881ba 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS08810 acd6b844cb4be588c5813cd27fc881ba 208 SUPERFAMILY SSF46689 4 83 3.99E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS24050 ae7e4db6abc8350945c3ee718063ef9a 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS24050 ae7e4db6abc8350945c3ee718063ef9a 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS24050 ae7e4db6abc8350945c3ee718063ef9a 204 Gene3D G3DSA:1.10.357.10 8 198 1.9E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS24050 ae7e4db6abc8350945c3ee718063ef9a 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 2.7E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS24050 ae7e4db6abc8350945c3ee718063ef9a 204 SUPERFAMILY SSF48498 83 194 5.5E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS24050 ae7e4db6abc8350945c3ee718063ef9a 204 SUPERFAMILY SSF46689 5 89 3.29E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS24050 ae7e4db6abc8350945c3ee718063ef9a 204 Pfam PF13977 Bacterial transcriptional repressor 85 198 2.3E-24 T 06-07-2017 LK06_RS07245 54454b53c785d0651937ca5b0c769882 207 Pfam PF01252 Signal peptidase (SPase) II 58 195 3.3E-28 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 LK06_RS07245 54454b53c785d0651937ca5b0c769882 207 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 176 192 1.0E-15 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 LK06_RS07245 54454b53c785d0651937ca5b0c769882 207 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 96 104 1.0E-15 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 LK06_RS07245 54454b53c785d0651937ca5b0c769882 207 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 138 153 1.0E-15 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 LK06_RS07245 54454b53c785d0651937ca5b0c769882 207 TIGRFAM TIGR00077 lspA: signal peptidase II 53 195 2.9E-23 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 LK06_RS07245 54454b53c785d0651937ca5b0c769882 207 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 49 201 14.441 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 LK06_RS07245 54454b53c785d0651937ca5b0c769882 207 ProSitePatterns PS00855 Signal peptidases II signature. 141 153 - T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 LK06_RS30340 4bba823d3c5bef9095fb463419b7b685 243 Pfam PF07729 FCD domain 98 218 4.1E-24 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS30340 4bba823d3c5bef9095fb463419b7b685 243 SMART SM00895 98 219 3.8E-18 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS30340 4bba823d3c5bef9095fb463419b7b685 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 2.7E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS30340 4bba823d3c5bef9095fb463419b7b685 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 2.7E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS30340 4bba823d3c5bef9095fb463419b7b685 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 81 1.7E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS30340 4bba823d3c5bef9095fb463419b7b685 243 Gene3D G3DSA:1.10.10.10 20 88 4.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30340 4bba823d3c5bef9095fb463419b7b685 243 Gene3D G3DSA:1.20.120.530 96 230 1.1E-31 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS30340 4bba823d3c5bef9095fb463419b7b685 243 SUPERFAMILY SSF48008 97 228 1.65E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS30340 4bba823d3c5bef9095fb463419b7b685 243 SUPERFAMILY SSF46785 15 85 6.23E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30340 4bba823d3c5bef9095fb463419b7b685 243 SMART SM00345 22 81 1.1E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 Pfam PF00342 Phosphoglucose isomerase 54 540 1.1E-220 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 Gene3D G3DSA:3.40.50.10490 101 293 1.8E-84 T 06-07-2017 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 SUPERFAMILY SSF53697 9 547 1.14E-207 T 06-07-2017 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 496 513 - T 06-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 Gene3D G3DSA:3.40.50.10490 296 505 1.3E-131 T 06-07-2017 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 Gene3D G3DSA:3.40.50.10490 11 100 1.3E-131 T 06-07-2017 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 48 523 41.104 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 Gene3D G3DSA:1.10.1390.10 506 547 8.5E-21 T 06-07-2017 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 341 362 4.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 496 509 4.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 264 282 4.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 482 496 4.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 152 171 4.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06600 447d94c526d4c6474369470d9468c3b9 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 464 482 4.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 Gene3D G3DSA:3.40.50.720 1 161 4.9E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 Gene3D G3DSA:1.10.1040.10 162 270 3.4E-36 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 228 240 - T 06-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 SUPERFAMILY SSF48179 158 290 1.5E-41 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 291 2.4E-100 T 06-07-2017 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 SUPERFAMILY SSF51735 1 143 3.45E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 224 251 1.7E-36 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 149 177 1.7E-36 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 1.7E-36 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 1.7E-36 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 1.7E-36 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 SMART SM01350 160 292 2.4E-6 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 160 270 2.4E-26 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS15845 ad3603968846583ae13ffd91e1ef9800 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 143 3.1E-37 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 LK06_RS04615 309222ce0e81b60db47bc547594bcfeb 168 Pfam PF04542 Sigma-70 region 2 5 70 9.4E-5 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS04615 309222ce0e81b60db47bc547594bcfeb 168 SUPERFAMILY SSF88659 82 158 8.22E-9 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS04615 309222ce0e81b60db47bc547594bcfeb 168 SUPERFAMILY SSF88946 5 80 8.24E-5 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS04615 309222ce0e81b60db47bc547594bcfeb 168 Gene3D G3DSA:1.10.10.10 98 158 4.0E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04615 309222ce0e81b60db47bc547594bcfeb 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 156 4.3E-14 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 SUPERFAMILY SSF55257 14 48 2.35E-24 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 SUPERFAMILY SSF55257 170 220 2.35E-24 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 Gene3D G3DSA:2.170.120.12 62 168 4.2E-45 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 311 2.0E-24 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.247 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 SMART SM00662 18 225 1.3E-94 T 06-07-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 Gene3D G3DSA:1.10.150.20 245 319 9.2E-32 T 06-07-2017 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 3.4E-115 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 SUPERFAMILY SSF47789 247 318 1.83E-23 T 06-07-2017 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 Gene3D G3DSA:3.30.1360.10 171 216 2.7E-4 T 06-07-2017 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 SUPERFAMILY SSF56553 48 169 4.97E-42 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 5.9E-26 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 2.4E-19 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 Gene3D G3DSA:3.30.1360.10 7 61 5.7E-11 T 06-07-2017 LK06_RS12175 d63792f3838b5c0a9e03c8a9275a6aa1 340 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 5.8E-24 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS24845 1184f36917b1ab6a800bb3179d68db9d 113 Gene3D G3DSA:1.10.287.1060 27 99 1.3E-8 T 06-07-2017 LK06_RS24845 1184f36917b1ab6a800bb3179d68db9d 113 Pfam PF06013 Proteins of 100 residues with WXG 25 82 6.2E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like LK06_RS24845 1184f36917b1ab6a800bb3179d68db9d 113 SUPERFAMILY SSF140453 15 95 1.01E-11 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like LK06_RS03790 52d322f71a0caa82e9887df942a73e67 317 Gene3D G3DSA:3.40.50.1110 2 191 1.2E-34 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS03790 52d322f71a0caa82e9887df942a73e67 317 SUPERFAMILY SSF52266 2 193 2.5E-36 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS03790 52d322f71a0caa82e9887df942a73e67 317 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 8 183 1.3E-24 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS02170 3fdfcb76b75e1d61c6400ab9b01ce721 358 SUPERFAMILY SSF56645 3 199 4.84E-23 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS02170 3fdfcb76b75e1d61c6400ab9b01ce721 358 Gene3D G3DSA:1.10.540.10 4 104 7.0E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS02170 3fdfcb76b75e1d61c6400ab9b01ce721 358 Gene3D G3DSA:1.20.140.10 214 351 1.5E-33 T 06-07-2017 LK06_RS02170 3fdfcb76b75e1d61c6400ab9b01ce721 358 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 104 9.5E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS02170 3fdfcb76b75e1d61c6400ab9b01ce721 358 SUPERFAMILY SSF47203 213 351 4.51E-34 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS02170 3fdfcb76b75e1d61c6400ab9b01ce721 358 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 211 350 3.6E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS31070 e38f2a4a0d05c32e7e0b0fd94c2c2e8e 415 Gene3D G3DSA:3.40.710.10 58 385 2.3E-81 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS31070 e38f2a4a0d05c32e7e0b0fd94c2c2e8e 415 Pfam PF00144 Beta-lactamase 65 385 2.1E-64 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS31070 e38f2a4a0d05c32e7e0b0fd94c2c2e8e 415 SUPERFAMILY SSF56601 56 381 6.11E-86 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS02050 bb0856c8c2df8ebe0dcccb97f1479655 631 SUPERFAMILY SSF90123 28 348 4.97E-72 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS02050 bb0856c8c2df8ebe0dcccb97f1479655 631 Gene3D G3DSA:1.20.1560.10 28 346 1.5E-70 T 06-07-2017 LK06_RS02050 bb0856c8c2df8ebe0dcccb97f1479655 631 ProSitePatterns PS00211 ABC transporters family signature. 516 530 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS02050 bb0856c8c2df8ebe0dcccb97f1479655 631 SUPERFAMILY SSF52540 356 615 3.84E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02050 bb0856c8c2df8ebe0dcccb97f1479655 631 SMART SM00382 404 590 4.0E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS02050 bb0856c8c2df8ebe0dcccb97f1479655 631 Pfam PF00005 ABC transporter 395 544 6.4E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS02050 bb0856c8c2df8ebe0dcccb97f1479655 631 Pfam PF00664 ABC transporter transmembrane region 44 312 4.3E-41 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS02050 bb0856c8c2df8ebe0dcccb97f1479655 631 Gene3D G3DSA:3.40.50.300 359 608 1.2E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4132 4246 2.4E-17 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2420 2535 1.8E-15 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 399 523 7.6E-9 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00825 Beta-ketoacyl synthase 2045 2470 4.4E-219 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00825 Beta-ketoacyl synthase 3757 4182 6.5E-221 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00825 Beta-ketoacyl synthase 36 448 2.6E-217 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.50.720 4891 5102 1.9E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF08659 KR domain 1681 1855 1.1E-55 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF08659 KR domain 4891 5058 2.3E-42 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF08659 KR domain 3384 3562 1.5E-59 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF14765 Polyketide synthase dehydratase 914 1182 3.7E-61 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF14765 Polyketide synthase dehydratase 2946 3215 1.0E-51 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM01294 1952 2019 1.1E-6 T 06-07-2017 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM01294 5168 5235 1.5E-4 T 06-07-2017 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM01294 3665 3732 4.5E-5 T 06-07-2017 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 281 396 4.0E-45 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2301 2417 8.9E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4013 4129 1.4E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00829 1376 1671 1.9E-165 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF51735 1187 1357 4.13E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5194 5209 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.30.70.250 680 743 3.1E-6 T 06-07-2017 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.30.70.250 2694 2759 1.8E-10 T 06-07-2017 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.30.70.250 4407 4470 2.7E-7 T 06-07-2017 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF53901 2039 2416 5.05E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1681 1857 8.0E-59 T 06-07-2017 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3384 3564 2.5E-62 T 06-07-2017 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4891 5060 2.5E-34 T 06-07-2017 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.366.10 2561 2691 4.7E-70 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.366.10 744 853 7.5E-64 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.366.10 555 675 7.5E-64 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.366.10 2760 2882 4.7E-70 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF47336 5160 5245 1.28E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF13602 Zinc-binding dehydrogenase 1551 1671 3.5E-17 T 06-07-2017 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2043 2293 4.3E-91 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 273 5.1E-86 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3755 4005 3.3E-90 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF00550 Phosphopantetheine attachment site 1954 2019 4.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF00550 Phosphopantetheine attachment site 5169 5235 1.2E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF00550 Phosphopantetheine attachment site 3665 3732 4.4E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF53901 3752 4129 7.74E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF52151 4472 4568 3.66E-69 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF52151 4279 4408 3.66E-69 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.47.10 3757 4017 4.1E-88 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.47.10 2045 2305 3.6E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1503 1524 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00826 913 1076 2.5E-78 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00826 2946 3108 1.1E-70 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00823 Phosphopantetheine attachment site 5167 5239 1.4E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00823 Phosphopantetheine attachment site 3664 3736 1.0E-26 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00823 Phosphopantetheine attachment site 1951 2023 2.3E-30 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1978 1993 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF52151 556 681 2.59E-60 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF52151 745 842 2.59E-60 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:1.10.1200.10 1948 2021 2.5E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:1.10.1200.10 3663 3737 1.5E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:1.10.1200.10 5163 5239 8.0E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF55048 4407 4471 2.88E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 186 202 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.90.180.10 1374 1508 2.9E-34 T 06-07-2017 IPR011032 GroES-like LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 558 849 4.6E-96 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4283 4576 3.7E-120 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2569 2880 6.9E-113 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF51735 3225 3372 3.54E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF50129 1370 1512 4.55E-24 T 06-07-2017 IPR011032 GroES-like LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3918 3934 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF55048 680 744 2.88E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.47.10 4018 4182 4.3E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.47.10 2306 2471 3.7E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.47.10 286 447 1.2E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF47336 3661 3770 6.94E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF51735 3382 3599 2.13E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF51735 1678 1908 1.86E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF51735 4684 4878 3.64E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF00698 Acyl transferase domain 2568 2899 1.4E-57 T 06-07-2017 IPR014043 Acyl transferase LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF00698 Acyl transferase domain 557 866 5.5E-54 T 06-07-2017 IPR014043 Acyl transferase LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF00698 Acyl transferase domain 4281 4594 2.6E-85 T 06-07-2017 IPR014043 Acyl transferase LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF51735 4887 5147 3.31E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.366.10 4471 4588 2.1E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.366.10 4273 4403 2.1E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF47336 1944 2055 8.9E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF52151 2565 2697 3.4E-67 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF52151 2761 2857 3.4E-67 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF53901 30 395 3.17E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.50.720 1681 1881 2.1E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.50.720 3384 3566 1.2E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF55048 2696 2760 5.36E-13 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3691 3706 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.50.720 1509 1598 2.3E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF51735 1474 1604 9.42E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF53474 2420 2616 3.99E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 SUPERFAMILY SSF53474 1982 2019 3.99E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Gene3D G3DSA:3.40.47.10 29 285 1.2E-94 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 Pfam PF08990 Erythronolide synthase docking 2 27 4.7E-8 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 LK06_RS29420 4ef991123bc06b8afd857b75b3d1636b 5316 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2206 2222 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS28390 157194347142ed334bb4963f34b2c86d 308 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 299 9.5E-78 T 06-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA LK06_RS28390 157194347142ed334bb4963f34b2c86d 308 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 307 4.3E-111 T 06-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA LK06_RS25030 9719abf388b92a799e6021cedb6c8be0 289 SUPERFAMILY SSF48239 234 286 9.68E-9 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS25030 9719abf388b92a799e6021cedb6c8be0 289 SUPERFAMILY SSF48239 32 136 9.68E-9 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS25030 9719abf388b92a799e6021cedb6c8be0 289 Gene3D G3DSA:1.50.10.20 234 285 3.3E-5 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS25030 9719abf388b92a799e6021cedb6c8be0 289 Gene3D G3DSA:1.50.10.20 33 139 3.3E-5 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS31580 56422117542bf3b7d6bd2b86885ec560 570 SUPERFAMILY SSF56645 49 216 4.45E-25 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS31580 56422117542bf3b7d6bd2b86885ec560 570 Pfam PF01756 Acyl-CoA oxidase 446 558 1.4E-9 T 06-07-2017 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS31580 56422117542bf3b7d6bd2b86885ec560 570 Gene3D G3DSA:2.40.110.10 95 223 1.7E-23 T 06-07-2017 LK06_RS31580 56422117542bf3b7d6bd2b86885ec560 570 SUPERFAMILY SSF47203 413 554 6.44E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS31580 56422117542bf3b7d6bd2b86885ec560 570 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 248 359 8.6E-8 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain LK06_RS31580 56422117542bf3b7d6bd2b86885ec560 570 Gene3D G3DSA:1.20.140.10 416 542 1.9E-13 T 06-07-2017 LK06_RS31580 56422117542bf3b7d6bd2b86885ec560 570 SUPERFAMILY SSF47203 235 394 5.64E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS31580 56422117542bf3b7d6bd2b86885ec560 570 PIRSF PIRSF000168 4 567 4.9E-94 T 06-07-2017 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0050660|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS31580 56422117542bf3b7d6bd2b86885ec560 570 Gene3D G3DSA:1.20.140.10 246 393 7.4E-35 T 06-07-2017 LK06_RS13535 f655f126d2e2e19f89526a1197d1b154 266 SMART SM00382 41 233 1.1E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS13535 f655f126d2e2e19f89526a1197d1b154 266 SUPERFAMILY SSF52540 15 238 6.39E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13535 f655f126d2e2e19f89526a1197d1b154 266 Gene3D G3DSA:3.40.50.300 8 242 1.9E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13535 f655f126d2e2e19f89526a1197d1b154 266 Pfam PF00005 ABC transporter 32 176 1.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS13535 f655f126d2e2e19f89526a1197d1b154 266 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS20485 3d05cf94329b7c892f7c9c4c906b81a9 482 Gene3D G3DSA:3.90.1150.10 329 477 3.3E-47 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS20485 3d05cf94329b7c892f7c9c4c906b81a9 482 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 268 284 - T 06-07-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS20485 3d05cf94329b7c892f7c9c4c906b81a9 482 Pfam PF00464 Serine hydroxymethyltransferase 156 430 5.8E-94 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS20485 3d05cf94329b7c892f7c9c4c906b81a9 482 Pfam PF00464 Serine hydroxymethyltransferase 22 123 7.1E-26 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS20485 3d05cf94329b7c892f7c9c4c906b81a9 482 Gene3D G3DSA:3.40.640.10 155 328 4.1E-90 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS20485 3d05cf94329b7c892f7c9c4c906b81a9 482 Gene3D G3DSA:3.40.640.10 49 123 4.1E-90 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS20485 3d05cf94329b7c892f7c9c4c906b81a9 482 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 19 477 44.61 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS20485 3d05cf94329b7c892f7c9c4c906b81a9 482 PIRSF PIRSF000412 4 481 3.5E-159 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS20485 3d05cf94329b7c892f7c9c4c906b81a9 482 SUPERFAMILY SSF53383 14 124 1.38E-145 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS20485 3d05cf94329b7c892f7c9c4c906b81a9 482 SUPERFAMILY SSF53383 156 478 1.38E-145 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS26605 e96ffb6fdaf9f2d134580beecaf88995 429 Gene3D G3DSA:1.10.150.80 257 305 9.4E-4 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 LK06_RS26605 e96ffb6fdaf9f2d134580beecaf88995 429 SUPERFAMILY SSF53098 34 246 6.5E-50 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS26605 e96ffb6fdaf9f2d134580beecaf88995 429 Pfam PF01612 3'-5' exonuclease 51 209 5.9E-34 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 LK06_RS26605 e96ffb6fdaf9f2d134580beecaf88995 429 Pfam PF00570 HRDC domain 251 317 3.5E-14 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 LK06_RS26605 e96ffb6fdaf9f2d134580beecaf88995 429 SMART SM00341 248 328 9.9E-21 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 LK06_RS26605 e96ffb6fdaf9f2d134580beecaf88995 429 Gene3D G3DSA:3.30.420.10 93 220 2.8E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS26605 e96ffb6fdaf9f2d134580beecaf88995 429 SMART SM00474 43 209 1.8E-36 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 LK06_RS26605 e96ffb6fdaf9f2d134580beecaf88995 429 SUPERFAMILY SSF47819 229 340 1.66E-25 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 LK06_RS28715 907bedf68752a777f956dc16b977aa88 262 SUPERFAMILY SSF52540 54 256 5.01E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28715 907bedf68752a777f956dc16b977aa88 262 SMART SM00382 68 251 3.7E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS28715 907bedf68752a777f956dc16b977aa88 262 Pfam PF00005 ABC transporter 60 193 2.3E-16 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS28715 907bedf68752a777f956dc16b977aa88 262 Gene3D G3DSA:3.40.50.300 54 259 7.1E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28715 907bedf68752a777f956dc16b977aa88 262 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS21430 24e00ec82c5081079c53c87cbf8ebc4c 229 Pfam PF04167 Protein of unknown function (DUF402) 99 163 1.3E-14 T 06-07-2017 IPR007295 Domain of unknown function DUF402 LK06_RS21430 24e00ec82c5081079c53c87cbf8ebc4c 229 Gene3D G3DSA:2.40.380.10 17 210 3.2E-73 T 06-07-2017 IPR007295 Domain of unknown function DUF402 LK06_RS21430 24e00ec82c5081079c53c87cbf8ebc4c 229 SUPERFAMILY SSF159234 42 212 2.88E-44 T 06-07-2017 LK06_RS13315 b27018d5b17b1bb44595d710d0a86dae 112 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 109 21.06 T 06-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 LK06_RS13315 b27018d5b17b1bb44595d710d0a86dae 112 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 3 109 3.0E-42 T 06-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 LK06_RS13315 b27018d5b17b1bb44595d710d0a86dae 112 SUPERFAMILY SSF103481 10 109 5.89E-12 T 06-07-2017 LK06_RS27995 561cec6ae0d9bf070a414c6c4633812a 324 Gene3D G3DSA:1.10.10.60 81 125 2.4E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS27995 561cec6ae0d9bf070a414c6c4633812a 324 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 107 130 2.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS27995 561cec6ae0d9bf070a414c6c4633812a 324 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 86 99 2.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS27995 561cec6ae0d9bf070a414c6c4633812a 324 SUPERFAMILY SSF46689 76 131 4.06E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS27995 561cec6ae0d9bf070a414c6c4633812a 324 ProSitePatterns PS01081 TetR-type HTH domain signature. 98 129 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS27995 561cec6ae0d9bf070a414c6c4633812a 324 Gene3D G3DSA:1.10.357.10 126 267 4.8E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS27995 561cec6ae0d9bf070a414c6c4633812a 324 Pfam PF00440 Bacterial regulatory proteins, tetR family 88 127 3.7E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 PRINTS PR00400 Tetracycline repressor protein signature 45 68 6.6E-8 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 PRINTS PR00400 Tetracycline repressor protein signature 162 181 6.6E-8 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 Gene3D G3DSA:1.10.357.10 82 247 1.0E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 SUPERFAMILY SSF48498 103 246 8.15E-30 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 ProSitePatterns PS01081 TetR-type HTH domain signature. 45 76 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 SUPERFAMILY SSF46689 22 90 3.64E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 77 2.7E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 Gene3D G3DSA:1.10.10.60 19 81 1.0E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 2.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS07955 0786e5e9c9aa4bdb38b696e2345086eb 248 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 102 245 7.8E-23 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 LK06_RS27025 48aaf412d6ca46871e59273e61971dfe 522 Pfam PF00135 Carboxylesterase family 8 457 3.7E-83 T 06-07-2017 IPR002018 Carboxylesterase, type B LK06_RS27025 48aaf412d6ca46871e59273e61971dfe 522 SUPERFAMILY SSF53474 7 484 1.59E-100 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27025 48aaf412d6ca46871e59273e61971dfe 522 Gene3D G3DSA:3.40.50.1820 8 484 8.7E-116 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27025 48aaf412d6ca46871e59273e61971dfe 522 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 178 193 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00825 Beta-ketoacyl synthase 15 426 1.2E-182 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00825 Beta-ketoacyl synthase 1016 1440 2.5E-222 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00825 Beta-ketoacyl synthase 2720 3144 2.6E-231 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00825 Beta-ketoacyl synthase 4441 4865 1.8E-215 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2881 2897 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF14765 Polyketide synthase dehydratase 5318 5583 1.1E-54 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF14765 Polyketide synthase dehydratase 3608 3876 3.2E-52 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF14765 Polyketide synthase dehydratase 1886 2157 3.3E-55 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4375 4390 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 533 831 5.3E-120 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1531 1822 1.1E-113 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3244 3542 2.7E-118 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4958 5252 1.0E-123 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.366.10 3432 3542 2.2E-72 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.366.10 721 831 2.7E-72 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.366.10 529 652 2.7E-72 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.366.10 3241 3363 2.2E-72 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF47336 2620 2733 6.02E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1392 1503 1.3E-12 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3094 3204 3.4E-13 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 376 494 3.1E-13 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4815 4930 1.3E-13 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF52151 4954 5082 1.02E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF52151 5146 5241 1.02E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF52151 3433 3529 5.23E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF52151 3241 3369 5.23E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF52151 1709 1813 7.06E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF52151 1528 1648 7.06E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF52151 722 817 7.59E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF52151 529 658 7.59E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF53901 2715 3088 8.35E-106 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1177 1193 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00823 Phosphopantetheine attachment site 907 979 6.5E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00823 Phosphopantetheine attachment site 2626 2698 1.0E-28 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00823 Phosphopantetheine attachment site 6047 6119 2.0E-29 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00823 Phosphopantetheine attachment site 4348 4420 2.2E-32 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.50.720 2343 2525 5.6E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.50.720 5768 5946 1.9E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.50.720 4064 4266 8.9E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF51735 3887 4050 6.3E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00550 Phosphopantetheine attachment site 909 975 9.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00550 Phosphopantetheine attachment site 4350 4416 1.6E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00550 Phosphopantetheine attachment site 6044 6115 1.9E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00550 Phosphopantetheine attachment site 2628 2694 1.2E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2653 2668 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.47.10 2981 3144 5.3E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.47.10 1277 1440 1.3E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.47.10 261 425 1.8E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.47.10 4702 4865 2.1E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF51735 2166 2328 1.34E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM01294 2627 2694 2.4E-4 T 06-07-2017 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM01294 4349 4416 3.4E-7 T 06-07-2017 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM01294 908 975 1.2E-5 T 06-07-2017 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF55048 1653 1716 1.57E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.47.10 10 260 1.2E-86 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF53901 4437 4809 4.49E-97 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.30.70.250 1651 1716 4.5E-8 T 06-07-2017 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.30.70.250 5080 5144 9.9E-9 T 06-07-2017 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.30.70.250 656 720 4.0E-7 T 06-07-2017 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.30.70.250 3367 3431 1.1E-8 T 06-07-2017 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1014 1264 6.6E-90 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4439 4689 8.1E-88 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2718 2968 8.6E-94 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 247 3.4E-71 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00698 Acyl transferase domain 1530 1839 2.1E-59 T 06-07-2017 IPR014043 Acyl transferase LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00698 Acyl transferase domain 531 850 1.1E-93 T 06-07-2017 IPR014043 Acyl transferase LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00698 Acyl transferase domain 3242 3560 2.9E-93 T 06-07-2017 IPR014043 Acyl transferase LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF00698 Acyl transferase domain 4957 5268 1.7E-56 T 06-07-2017 IPR014043 Acyl transferase LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4602 4618 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4064 4244 4.6E-58 T 06-07-2017 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2343 2523 2.8E-52 T 06-07-2017 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5768 5944 9.0E-56 T 06-07-2017 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF47336 901 981 6.28E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF51735 2341 2576 5.87E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF47336 4344 4453 1.7E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 934 949 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.47.10 2720 2980 3.9E-95 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.47.10 1016 1276 2.6E-93 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.47.10 4441 4701 8.0E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.366.10 4952 5076 5.0E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.366.10 5145 5253 5.0E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00826 1886 2045 3.1E-69 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00826 5318 5480 3.7E-84 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SMART SM00826 3608 3775 1.6E-77 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF53901 12 369 4.52E-84 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF53901 401 416 4.52E-84 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:1.10.1200.10 905 979 9.5E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:1.10.1200.10 6043 6121 2.8E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:1.10.1200.10 2623 2699 2.6E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:1.10.1200.10 4345 4420 7.2E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF51735 5767 5993 5.91E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF47336 6040 6129 4.71E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF55048 3367 3432 1.14E-13 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF08659 KR domain 4064 4243 1.9E-58 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF08659 KR domain 5769 5943 1.6E-58 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF08659 KR domain 2343 2521 1.3E-59 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF53901 1012 1384 3.52E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF55048 5080 5145 3.01E-13 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.366.10 1519 1649 1.6E-78 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Gene3D G3DSA:3.40.366.10 1717 1835 1.6E-78 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF55048 656 721 1.09E-12 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2976 3091 3.1E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4697 4812 3.9E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1272 1387 2.5E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 374 6.3E-39 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6074 6089 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF51735 4062 4299 1.93E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25670 350e7e2dd2ebdd3623a1848bad83eb93 6191 SUPERFAMILY SSF51735 5587 5754 8.27E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12450 c18eae92997fa176d394f612d514e89d 241 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 1.3E-52 T 06-07-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein LK06_RS12450 c18eae92997fa176d394f612d514e89d 241 PIRSF PIRSF002155 1 227 5.9E-75 T 06-07-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12450 c18eae92997fa176d394f612d514e89d 241 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 2.3E-102 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 LK06_RS12450 c18eae92997fa176d394f612d514e89d 241 Gene3D G3DSA:3.30.190.20 161 226 4.2E-46 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 LK06_RS12450 c18eae92997fa176d394f612d514e89d 241 Gene3D G3DSA:3.30.190.20 16 68 4.2E-46 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 LK06_RS12450 c18eae92997fa176d394f612d514e89d 241 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.083 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 LK06_RS12450 c18eae92997fa176d394f612d514e89d 241 Gene3D G3DSA:3.40.50.790 69 159 8.1E-41 T 06-07-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich LK06_RS12450 c18eae92997fa176d394f612d514e89d 241 SUPERFAMILY SSF56808 7 227 1.02E-83 T 06-07-2017 IPR023674 Ribosomal protein L1-like LK06_RS12450 c18eae92997fa176d394f612d514e89d 241 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 06-07-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 Pfam PF01037 Lrp/AsnC ligand binding domain 244 313 2.3E-11 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 SUPERFAMILY SSF54909 66 139 1.1E-5 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 Gene3D G3DSA:3.30.70.920 241 315 3.9E-13 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 Gene3D G3DSA:3.30.70.920 68 140 5.7E-9 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 Gene3D G3DSA:1.10.10.10 175 223 5.2E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 Gene3D G3DSA:1.10.10.10 6 52 3.8E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 SMART SM00344 6 109 3.5E-5 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 SMART SM00344 177 282 1.2E-5 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 SUPERFAMILY SSF46785 176 223 6.61E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 SUPERFAMILY SSF46785 6 52 4.67E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 SUPERFAMILY SSF54909 241 315 8.04E-11 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 Pfam PF13404 AsnC-type helix-turn-helix domain 6 46 7.6E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 Pfam PF13404 AsnC-type helix-turn-helix domain 177 218 4.3E-11 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 193 204 3.7E-8 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 204 223 3.7E-8 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS32280 9bd4d3298dac9eb06955cc2075d9e143 327 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 177 193 3.7E-8 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS00515 e16934a272c61660ca07445b71c264fb 177 Pfam PF01047 MarR family 44 100 4.5E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS00515 e16934a272c61660ca07445b71c264fb 177 SMART SM00347 36 136 9.0E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS00515 e16934a272c61660ca07445b71c264fb 177 SUPERFAMILY SSF46785 14 149 6.82E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00515 e16934a272c61660ca07445b71c264fb 177 Gene3D G3DSA:1.10.10.10 6 148 1.4E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08255 dfddeb71f733ce232f8b8d1e99e9435c 234 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 25 231 6.6E-80 T 06-07-2017 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 LK06_RS08255 dfddeb71f733ce232f8b8d1e99e9435c 234 Gene3D G3DSA:3.40.50.720 26 227 4.5E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08255 dfddeb71f733ce232f8b8d1e99e9435c 234 SUPERFAMILY SSF51735 26 228 1.68E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08255 dfddeb71f733ce232f8b8d1e99e9435c 234 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 26 117 1.6E-22 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal LK06_RS07550 7b4e19a2c12e97ea1f031ada0f278e5f 598 SUPERFAMILY SSF56801 17 288 6.67E-119 T 06-07-2017 LK06_RS07550 7b4e19a2c12e97ea1f031ada0f278e5f 598 SUPERFAMILY SSF56801 337 596 6.67E-119 T 06-07-2017 LK06_RS07550 7b4e19a2c12e97ea1f031ada0f278e5f 598 Gene3D G3DSA:3.30.300.30 464 583 2.4E-5 T 06-07-2017 LK06_RS07550 7b4e19a2c12e97ea1f031ada0f278e5f 598 Gene3D G3DSA:3.40.50.980 334 396 7.0E-28 T 06-07-2017 LK06_RS07550 7b4e19a2c12e97ea1f031ada0f278e5f 598 Gene3D G3DSA:3.40.50.980 190 283 7.0E-28 T 06-07-2017 LK06_RS07550 7b4e19a2c12e97ea1f031ada0f278e5f 598 Gene3D G3DSA:2.30.38.10 397 457 1.1E-20 T 06-07-2017 LK06_RS07550 7b4e19a2c12e97ea1f031ada0f278e5f 598 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 112 123 - T 06-07-2017 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 LK06_RS07550 7b4e19a2c12e97ea1f031ada0f278e5f 598 Pfam PF00501 AMP-binding enzyme 23 466 9.1E-106 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS07550 7b4e19a2c12e97ea1f031ada0f278e5f 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS07550 7b4e19a2c12e97ea1f031ada0f278e5f 598 Gene3D G3DSA:3.40.50.980 17 189 6.3E-38 T 06-07-2017 LK06_RS27990 cc9a7aa48c1f897394cb1fe5a859bfcc 447 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 33 430 2.4E-191 T 06-07-2017 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 LK06_RS27990 cc9a7aa48c1f897394cb1fe5a859bfcc 447 SMART SM00829 51 417 4.4E-11 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS27990 cc9a7aa48c1f897394cb1fe5a859bfcc 447 Gene3D G3DSA:3.40.50.720 234 366 2.0E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27990 cc9a7aa48c1f897394cb1fe5a859bfcc 447 SUPERFAMILY SSF50129 52 232 3.5E-28 T 06-07-2017 IPR011032 GroES-like LK06_RS27990 cc9a7aa48c1f897394cb1fe5a859bfcc 447 SUPERFAMILY SSF51735 200 393 1.16E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27990 cc9a7aa48c1f897394cb1fe5a859bfcc 447 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 115 191 2.4E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS27990 cc9a7aa48c1f897394cb1fe5a859bfcc 447 Pfam PF00107 Zinc-binding dehydrogenase 238 382 1.8E-38 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS27990 cc9a7aa48c1f897394cb1fe5a859bfcc 447 Gene3D G3DSA:3.90.180.10 44 233 6.9E-31 T 06-07-2017 IPR011032 GroES-like LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 SUPERFAMILY SSF55031 204 249 1.28E-11 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 SUPERFAMILY SSF55031 290 329 1.28E-11 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 Pfam PF01546 Peptidase family M20/M25/M40 84 439 1.6E-35 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 Gene3D G3DSA:3.30.70.360 214 253 1.3E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 Gene3D G3DSA:3.30.70.360 291 328 1.3E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 Gene3D G3DSA:3.40.630.10 376 439 1.2E-60 T 06-07-2017 LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 Gene3D G3DSA:3.40.630.10 13 213 1.2E-60 T 06-07-2017 LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 Pfam PF07687 Peptidase dimerisation domain 201 328 4.8E-15 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 83 92 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 SUPERFAMILY SSF53187 351 438 1.49E-53 T 06-07-2017 LK06_RS05195 679b0d4f3174781ed098f3cc7c532c01 441 SUPERFAMILY SSF53187 13 204 1.49E-53 T 06-07-2017 LK06_RS27645 bf5ce857213c00ad6cdea3cf953a1c39 407 Gene3D G3DSA:1.20.1250.20 214 378 6.4E-9 T 06-07-2017 LK06_RS27645 bf5ce857213c00ad6cdea3cf953a1c39 407 Gene3D G3DSA:1.20.1250.20 4 186 3.5E-24 T 06-07-2017 LK06_RS27645 bf5ce857213c00ad6cdea3cf953a1c39 407 Pfam PF07690 Major Facilitator Superfamily 9 306 4.2E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS27645 bf5ce857213c00ad6cdea3cf953a1c39 407 SUPERFAMILY SSF103473 3 383 7.46E-46 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS32130 5127de6c8c26eb765f583af7b060f6d6 413 Gene3D G3DSA:1.20.1250.20 209 397 6.9E-16 T 06-07-2017 LK06_RS32130 5127de6c8c26eb765f583af7b060f6d6 413 SUPERFAMILY SSF103473 49 388 7.46E-33 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS32130 5127de6c8c26eb765f583af7b060f6d6 413 Pfam PF07690 Major Facilitator Superfamily 51 355 2.0E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS32130 5127de6c8c26eb765f583af7b060f6d6 413 Gene3D G3DSA:1.20.1250.20 50 191 1.1E-10 T 06-07-2017 LK06_RS09605 033cb9007a98bd9d046a5109030690a1 222 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 17 209 2.9E-55 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS09605 033cb9007a98bd9d046a5109030690a1 222 SUPERFAMILY SSF53254 15 213 1.81E-55 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS09605 033cb9007a98bd9d046a5109030690a1 222 Gene3D G3DSA:3.40.50.1240 15 210 8.4E-58 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS09605 033cb9007a98bd9d046a5109030690a1 222 SMART SM00855 16 170 2.1E-23 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS09605 033cb9007a98bd9d046a5109030690a1 222 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 19 28 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 LK06_RS14085 784326272a146fc1498d23f16db0ac78 807 Pfam PF00916 Sulfate permease family 43 407 1.1E-54 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 LK06_RS14085 784326272a146fc1498d23f16db0ac78 807 Pfam PF00484 Carbonic anhydrase 594 756 1.0E-44 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS14085 784326272a146fc1498d23f16db0ac78 807 Gene3D G3DSA:3.40.1050.10 554 767 1.9E-78 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS14085 784326272a146fc1498d23f16db0ac78 807 SMART SM00947 586 762 2.0E-53 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS14085 784326272a146fc1498d23f16db0ac78 807 Gene3D G3DSA:3.30.750.24 441 521 2.7E-4 T 06-07-2017 IPR002645 STAS domain LK06_RS14085 784326272a146fc1498d23f16db0ac78 807 SUPERFAMILY SSF52091 441 521 7.85E-5 T 06-07-2017 IPR002645 STAS domain LK06_RS14085 784326272a146fc1498d23f16db0ac78 807 SUPERFAMILY SSF53056 558 761 9.68E-52 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 SUPERFAMILY SSF52821 225 338 1.7E-12 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 SUPERFAMILY SSF52821 347 455 3.4E-31 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 Pfam PF00753 Metallo-beta-lactamase superfamily 11 185 8.3E-8 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 SMART SM00450 259 358 7.6 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 SMART SM00450 363 458 2.3E-24 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 Pfam PF00581 Rhodanese-like domain 363 453 9.9E-13 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 SUPERFAMILY SSF56281 12 238 9.24E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 Gene3D G3DSA:3.40.250.10 239 338 3.0E-9 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 Gene3D G3DSA:3.40.250.10 348 454 1.0E-28 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 Gene3D G3DSA:3.60.15.10 10 238 5.1E-52 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS25800 42cec98b278763cfafe6fb1cca0db4f4 461 SMART SM00849 12 185 3.0E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS04985 bd9bd8a6cfed850ed02af522fb10843f 126 Gene3D G3DSA:3.10.50.40 13 123 9.1E-42 T 06-07-2017 LK06_RS04985 bd9bd8a6cfed850ed02af522fb10843f 126 SUPERFAMILY SSF54534 15 123 7.27E-39 T 06-07-2017 LK06_RS04985 bd9bd8a6cfed850ed02af522fb10843f 126 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 31 120 1.4E-30 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 LK06_RS10975 bc4cfaf62fb92a531046b3778719b120 547 Gene3D G3DSA:3.30.300.30 418 513 7.2E-13 T 06-07-2017 LK06_RS10975 bc4cfaf62fb92a531046b3778719b120 547 Pfam PF00501 AMP-binding enzyme 26 423 3.5E-55 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS10975 bc4cfaf62fb92a531046b3778719b120 547 Gene3D G3DSA:3.40.50.980 177 321 1.7E-22 T 06-07-2017 LK06_RS10975 bc4cfaf62fb92a531046b3778719b120 547 Gene3D G3DSA:2.30.38.10 353 417 3.8E-15 T 06-07-2017 LK06_RS10975 bc4cfaf62fb92a531046b3778719b120 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 505 9.7E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS10975 bc4cfaf62fb92a531046b3778719b120 547 Gene3D G3DSA:3.40.50.980 12 176 7.9E-15 T 06-07-2017 LK06_RS10975 bc4cfaf62fb92a531046b3778719b120 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS10975 bc4cfaf62fb92a531046b3778719b120 547 SUPERFAMILY SSF56801 14 518 1.7E-91 T 06-07-2017 LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 Pfam PF00512 His Kinase A (phospho-acceptor) domain 368 431 3.4E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 SMART SM00387 476 586 2.9E-42 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 Pfam PF00672 HAMP domain 297 358 4.4E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 Gene3D G3DSA:1.10.287.130 361 417 1.1E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 Gene3D G3DSA:3.30.565.10 418 586 4.9E-47 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 SUPERFAMILY SSF47384 350 431 3.14E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 585 3.1E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 527 1.3E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 566 1.3E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 572 585 1.3E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 541 1.3E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 SMART SM00388 367 431 3.4E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS19160 159e10bb3d8d4f18e2e05d043194a258 586 SUPERFAMILY SSF55874 420 585 2.23E-48 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 SUPERFAMILY SSF55347 157 318 3.7E-64 T 06-07-2017 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 Gene3D G3DSA:3.30.360.10 166 319 8.5E-68 T 06-07-2017 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 SMART SM00846 3 157 4.5E-76 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 329 9.8E-124 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 Gene3D G3DSA:3.40.50.720 1 165 4.4E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 274 289 2.0E-31 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 178 194 2.0E-31 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 234 251 2.0E-31 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 151 169 2.0E-31 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 114 127 2.0E-31 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 SUPERFAMILY SSF51735 3 173 2.87E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 157 7.1E-54 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 155 162 - T 06-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 162 317 4.2E-60 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS11515 5a8718a472e5af3380df4e6b7e0594ea 337 PIRSF PIRSF000149 1 337 3.4E-123 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS31905 a127c886867d13d975376c2c7f43f30c 548 SUPERFAMILY SSF56801 23 534 3.79E-98 T 06-07-2017 LK06_RS31905 a127c886867d13d975376c2c7f43f30c 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 519 1.8E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS31905 a127c886867d13d975376c2c7f43f30c 548 Pfam PF00501 AMP-binding enzyme 27 435 4.2E-61 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS31905 a127c886867d13d975376c2c7f43f30c 548 Gene3D G3DSA:3.40.50.980 28 193 8.2E-19 T 06-07-2017 LK06_RS31905 a127c886867d13d975376c2c7f43f30c 548 Gene3D G3DSA:2.30.38.10 356 425 9.9E-21 T 06-07-2017 LK06_RS31905 a127c886867d13d975376c2c7f43f30c 548 Gene3D G3DSA:3.40.50.980 194 355 1.1E-22 T 06-07-2017 LK06_RS31905 a127c886867d13d975376c2c7f43f30c 548 Gene3D G3DSA:3.30.300.30 431 528 1.1E-21 T 06-07-2017 LK06_RS31905 a127c886867d13d975376c2c7f43f30c 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS03905 2b4c01553a7e821626dd77763aa1d0ca 206 SUPERFAMILY SSF52540 8 170 1.9E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03905 2b4c01553a7e821626dd77763aa1d0ca 206 Gene3D G3DSA:3.40.50.300 16 173 2.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31135 e59f78a2ec04ff6fe6b9fe35c32c1acb 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 48 1.5E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS31135 e59f78a2ec04ff6fe6b9fe35c32c1acb 189 SUPERFAMILY SSF48498 78 180 6.08E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS31135 e59f78a2ec04ff6fe6b9fe35c32c1acb 189 Gene3D G3DSA:1.10.10.60 1 49 3.9E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS31135 e59f78a2ec04ff6fe6b9fe35c32c1acb 189 SUPERFAMILY SSF46689 5 72 2.84E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS31135 e59f78a2ec04ff6fe6b9fe35c32c1acb 189 Pfam PF13305 WHG domain 84 159 6.8E-7 T 06-07-2017 IPR025996 WHG domain LK06_RS31135 e59f78a2ec04ff6fe6b9fe35c32c1acb 189 Gene3D G3DSA:1.10.357.10 51 184 3.9E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS27650 91c9673e49ea0f544d5a4c3340367308 194 SUPERFAMILY SSF160904 4 186 3.92E-41 T 06-07-2017 LK06_RS27650 91c9673e49ea0f544d5a4c3340367308 194 Gene3D G3DSA:1.10.3300.10 4 187 6.5E-44 T 06-07-2017 IPR023286 ABATE domain LK06_RS27650 91c9673e49ea0f544d5a4c3340367308 194 Pfam PF07336 Putative stress-induced transcription regulator 10 140 2.6E-22 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator LK06_RS27650 91c9673e49ea0f544d5a4c3340367308 194 Pfam PF11706 CGNR zinc finger 145 188 1.0E-16 T 06-07-2017 IPR021005 Zinc finger, CGNR LK06_RS23405 3807d1c5010ad18079cdfe6189642575 445 Pfam PF00005 ABC transporter 19 156 4.1E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS23405 3807d1c5010ad18079cdfe6189642575 445 SMART SM00382 26 204 7.0E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS23405 3807d1c5010ad18079cdfe6189642575 445 Gene3D G3DSA:3.40.50.300 1 224 5.9E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23405 3807d1c5010ad18079cdfe6189642575 445 SUPERFAMILY SSF52540 2 221 3.93E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20480 64d0093713f6eb3732ddce5e43be49eb 401 Gene3D G3DSA:3.90.1150.10 291 399 1.5E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS20480 64d0093713f6eb3732ddce5e43be49eb 401 Pfam PF00202 Aminotransferase class-III 18 399 1.2E-110 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS20480 64d0093713f6eb3732ddce5e43be49eb 401 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS20480 64d0093713f6eb3732ddce5e43be49eb 401 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 5 398 5.8E-141 T 06-07-2017 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LK06_RS20480 64d0093713f6eb3732ddce5e43be49eb 401 SUPERFAMILY SSF53383 5 399 6.68E-116 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS20480 64d0093713f6eb3732ddce5e43be49eb 401 Gene3D G3DSA:3.40.640.10 60 290 6.2E-82 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 Gene3D G3DSA:3.40.50.920 487 619 6.7E-33 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 SUPERFAMILY SSF52518 2 345 2.36E-71 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 SMART SM00861 315 479 7.1E-46 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 Gene3D G3DSA:3.40.50.970 239 330 5.9E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 Gene3D G3DSA:3.40.50.970 18 194 5.9E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 SUPERFAMILY SSF52922 486 620 1.31E-29 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 Pfam PF02779 Transketolase, pyrimidine binding domain 315 477 4.1E-35 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 617 1.5E-190 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 3.6E-109 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 621 41.572 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 Gene3D G3DSA:3.40.50.970 331 479 9.1E-27 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 SUPERFAMILY SSF52518 294 477 1.55E-48 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 Pfam PF02780 Transketolase, C-terminal domain 499 612 4.4E-31 T 06-07-2017 IPR033248 Transketolase, C-terminal domain LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS26565 375b73ed5e8dfd041fce8f23e12fa5d7 642 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00382 602 741 2.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 Gene3D G3DSA:2.160.20.10 388 482 3.2E-7 T 06-07-2017 IPR012334 Pectin lyase fold LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 Gene3D G3DSA:2.160.20.10 11 265 8.7E-21 T 06-07-2017 IPR012334 Pectin lyase fold LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SUPERFAMILY SSF51126 356 507 2.4E-14 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 185 207 480.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 396 417 1500.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 441 463 6.7 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 464 486 8600.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 162 184 670.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 418 440 20.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 373 394 4700.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 278 300 4200.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 350 372 7000.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 232 254 650.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00710 139 161 19.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SUPERFAMILY SSF51126 31 253 4.44E-27 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00722 324 485 5.7E-9 T 06-07-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SMART SM00722 52 183 0.0068 T 06-07-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 PRINTS PR00819 CbxX/CfqX superfamily signature 643 657 3.8E-47 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 PRINTS PR00819 CbxX/CfqX superfamily signature 709 726 3.8E-47 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 PRINTS PR00819 CbxX/CfqX superfamily signature 657 676 3.8E-47 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 PRINTS PR00819 CbxX/CfqX superfamily signature 726 745 3.8E-47 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 PRINTS PR00819 CbxX/CfqX superfamily signature 688 700 3.8E-47 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 PRINTS PR00819 CbxX/CfqX superfamily signature 783 795 3.8E-47 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 PRINTS PR00819 CbxX/CfqX superfamily signature 565 579 3.8E-47 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 PRINTS PR00819 CbxX/CfqX superfamily signature 605 620 3.8E-47 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 607 737 4.6E-17 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 Pfam PF13229 Right handed beta helix region 132 265 4.5E-15 T 06-07-2017 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 Pfam PF13229 Right handed beta helix region 396 502 1.3E-8 T 06-07-2017 LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 Gene3D G3DSA:3.40.50.300 566 754 3.0E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30100 4633fd1d35fe45f415f16f0b03772cc5 825 SUPERFAMILY SSF52540 564 772 1.58E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 Gene3D G3DSA:3.40.1390.10 32 116 5.2E-22 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 SUPERFAMILY SSF53244 347 506 2.35E-44 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 Pfam PF08245 Mur ligase middle domain 126 326 8.6E-53 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 SUPERFAMILY SSF53623 117 346 4.01E-68 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 15 504 33.683 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 Gene3D G3DSA:3.90.190.20 351 498 5.4E-50 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 SUPERFAMILY SSF63418 31 116 2.22E-21 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 Pfam PF01225 Mur ligase family, catalytic domain 38 113 3.8E-12 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 Pfam PF02875 Mur ligase family, glutamate ligase domain 347 431 4.1E-20 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 38 504 1.0E-145 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 LK06_RS07325 eb176ddf1cc9980dc127dc6cdbd2609e 509 Gene3D G3DSA:3.40.1190.10 120 350 5.3E-80 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS20395 0281b09d3da9a793f8b0e1b11028aecf 329 SUPERFAMILY SSF56327 157 324 3.4E-62 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 LK06_RS20395 0281b09d3da9a793f8b0e1b11028aecf 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 1.5E-31 T 06-07-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 LK06_RS20395 0281b09d3da9a793f8b0e1b11028aecf 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 57.38 T 06-07-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 LK06_RS20395 0281b09d3da9a793f8b0e1b11028aecf 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 323 3.6E-35 T 06-07-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 LK06_RS20395 0281b09d3da9a793f8b0e1b11028aecf 329 PIRSF PIRSF000102 2 328 2.1E-62 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 LK06_RS20395 0281b09d3da9a793f8b0e1b11028aecf 329 Gene3D G3DSA:3.40.50.720 5 154 8.9E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20395 0281b09d3da9a793f8b0e1b11028aecf 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 1.5E-146 T 06-07-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 LK06_RS20395 0281b09d3da9a793f8b0e1b11028aecf 329 Gene3D G3DSA:3.90.110.10 156 326 5.3E-77 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 LK06_RS20395 0281b09d3da9a793f8b0e1b11028aecf 329 SUPERFAMILY SSF51735 4 156 1.89E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20395 0281b09d3da9a793f8b0e1b11028aecf 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 06-07-2017 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 LK06_RS01235 1d00ef01559b29ecb0514c37849c6374 223 Gene3D G3DSA:1.10.10.10 132 198 4.3E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01235 1d00ef01559b29ecb0514c37849c6374 223 Pfam PF08448 PAS fold 19 124 1.3E-11 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS01235 1d00ef01559b29ecb0514c37849c6374 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 192 9.8E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS01235 1d00ef01559b29ecb0514c37849c6374 223 SUPERFAMILY SSF46894 126 198 1.36E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS01235 1d00ef01559b29ecb0514c37849c6374 223 SUPERFAMILY SSF55785 13 111 1.74E-14 T 06-07-2017 IPR000014 PAS domain LK06_RS01235 1d00ef01559b29ecb0514c37849c6374 223 Gene3D G3DSA:3.30.450.20 15 119 1.0E-15 T 06-07-2017 LK06_RS01235 1d00ef01559b29ecb0514c37849c6374 223 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 115 3.3E-11 T 06-07-2017 IPR000014 PAS domain LK06_RS01235 1d00ef01559b29ecb0514c37849c6374 223 SMART SM00091 13 79 7.0E-4 T 06-07-2017 IPR000014 PAS domain LK06_RS01235 1d00ef01559b29ecb0514c37849c6374 223 SMART SM00421 136 193 9.9E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11425 436c8547c98029ce1b2f32391547717d 446 SUPERFAMILY SSF55205 7 440 9.59E-112 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 LK06_RS11425 436c8547c98029ce1b2f32391547717d 446 Gene3D G3DSA:3.65.10.10 25 228 3.3E-52 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 LK06_RS11425 436c8547c98029ce1b2f32391547717d 446 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 7 439 1.4E-130 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS11425 436c8547c98029ce1b2f32391547717d 446 Gene3D G3DSA:3.65.10.10 229 439 2.9E-48 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 LK06_RS11425 436c8547c98029ce1b2f32391547717d 446 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 11 431 3.3E-57 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 LK06_RS15240 ef3e2adb9868b94b3917195568985815 413 Pfam PF07687 Peptidase dimerisation domain 193 281 5.9E-10 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS15240 ef3e2adb9868b94b3917195568985815 413 Gene3D G3DSA:3.30.70.360 189 306 4.2E-33 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS15240 ef3e2adb9868b94b3917195568985815 413 Pfam PF01546 Peptidase family M20/M25/M40 78 357 6.3E-24 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 LK06_RS15240 ef3e2adb9868b94b3917195568985815 413 PIRSF PIRSF005962 14 412 3.3E-94 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 LK06_RS15240 ef3e2adb9868b94b3917195568985815 413 SUPERFAMILY SSF55031 192 299 1.08E-26 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS15240 ef3e2adb9868b94b3917195568985815 413 SUPERFAMILY SSF53187 307 410 1.5E-76 T 06-07-2017 LK06_RS15240 ef3e2adb9868b94b3917195568985815 413 SUPERFAMILY SSF53187 18 204 1.5E-76 T 06-07-2017 LK06_RS15240 ef3e2adb9868b94b3917195568985815 413 Gene3D G3DSA:3.40.630.10 307 411 1.7E-83 T 06-07-2017 LK06_RS15240 ef3e2adb9868b94b3917195568985815 413 Gene3D G3DSA:3.40.630.10 19 185 1.7E-83 T 06-07-2017 LK06_RS15240 ef3e2adb9868b94b3917195568985815 413 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 23 345 1.2E-84 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 LK06_RS19100 50f83666326f7619f6c0b5114a098cd6 217 Pfam PF16316 Domain of unknown function (DUF4956) 27 195 4.3E-41 T 06-07-2017 IPR032531 Protein of unknown function DUF4956 LK06_RS14180 f19544896729e0ae216408404f794ee7 764 Gene3D G3DSA:1.10.3810.10 63 251 1.5E-71 T 06-07-2017 LK06_RS14180 f19544896729e0ae216408404f794ee7 764 SUPERFAMILY SSF56601 287 675 1.11E-92 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS14180 f19544896729e0ae216408404f794ee7 764 SUPERFAMILY SSF56601 231 253 1.11E-92 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS14180 f19544896729e0ae216408404f794ee7 764 Pfam PF00912 Transglycosylase 63 249 5.7E-63 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 LK06_RS14180 f19544896729e0ae216408404f794ee7 764 Pfam PF00905 Penicillin binding protein transpeptidase domain 350 625 1.3E-28 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS14180 f19544896729e0ae216408404f794ee7 764 SUPERFAMILY SSF53955 51 274 6.19E-70 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS14180 f19544896729e0ae216408404f794ee7 764 Gene3D G3DSA:3.40.710.10 252 675 4.2E-108 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS25415 582878c22840aa81d7a6f068859f5f89 216 Pfam PF00265 Thymidine kinase 4 192 6.5E-22 T 06-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 LK06_RS25415 582878c22840aa81d7a6f068859f5f89 216 PIRSF PIRSF035805 1 205 9.0E-36 T 06-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 LK06_RS25415 582878c22840aa81d7a6f068859f5f89 216 SUPERFAMILY SSF57716 144 197 1.52E-8 T 06-07-2017 LK06_RS25415 582878c22840aa81d7a6f068859f5f89 216 Gene3D G3DSA:3.40.50.300 4 123 7.8E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25415 582878c22840aa81d7a6f068859f5f89 216 SUPERFAMILY SSF52540 1 139 9.77E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25415 582878c22840aa81d7a6f068859f5f89 216 Gene3D G3DSA:3.30.60.20 144 195 1.1E-4 T 06-07-2017 LK06_RS25415 582878c22840aa81d7a6f068859f5f89 216 Hamap MF_00124 Thymidine kinase [tdk]. 1 195 28.019 T 06-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 LK06_RS30165 9d45dc84a605c059bf90bbb2db77b2af 252 SMART SM00824 Thioesterase 26 249 8.2E-4 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 LK06_RS30165 9d45dc84a605c059bf90bbb2db77b2af 252 Gene3D G3DSA:3.40.50.1820 9 240 2.8E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30165 9d45dc84a605c059bf90bbb2db77b2af 252 SUPERFAMILY SSF53474 12 249 1.25E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30165 9d45dc84a605c059bf90bbb2db77b2af 252 Pfam PF00975 Thioesterase domain 24 245 3.8E-58 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS07390 8a70e68ec02f09c9a64440f630695bf2 209 Gene3D G3DSA:1.10.357.10 73 203 7.6E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS07390 8a70e68ec02f09c9a64440f630695bf2 209 Gene3D G3DSA:1.10.10.60 51 72 1.3E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS07390 8a70e68ec02f09c9a64440f630695bf2 209 SUPERFAMILY SSF48498 94 201 1.53E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS07390 8a70e68ec02f09c9a64440f630695bf2 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS07390 8a70e68ec02f09c9a64440f630695bf2 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS07390 8a70e68ec02f09c9a64440f630695bf2 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 3.6E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS07390 8a70e68ec02f09c9a64440f630695bf2 209 Gene3D G3DSA:1.10.10.60 10 50 3.3E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS07390 8a70e68ec02f09c9a64440f630695bf2 209 SUPERFAMILY SSF46689 12 86 1.28E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 Pfam PF04539 Sigma-70 region 3 177 235 1.7E-11 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 91 313 1.5E-95 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 SUPERFAMILY SSF88659 169 244 1.09E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 PRINTS PR00046 Major sigma-70 factor signature 120 133 4.5E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 PRINTS PR00046 Major sigma-70 factor signature 267 279 4.5E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 PRINTS PR00046 Major sigma-70 factor signature 284 299 4.5E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 SUPERFAMILY SSF88659 231 314 2.43E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 Pfam PF04542 Sigma-70 region 2 96 165 1.6E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 Gene3D G3DSA:1.10.10.10 164 219 2.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 SUPERFAMILY SSF88946 72 165 7.59E-31 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 Pfam PF04545 Sigma-70, region 4 263 312 4.5E-18 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 93 313 8.5E-36 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 120 133 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 Gene3D G3DSA:1.10.601.10 88 163 6.9E-24 T 06-07-2017 LK06_RS16670 a85ba3c6317de787578a1cade2cd3e12 317 Gene3D G3DSA:1.10.10.10 255 314 6.6E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12630 1665b1bf4fac04500da10cb6d0ea7dd2 287 Hamap MF_00188 Protease HtpX [htpX]. 7 282 28.128 T 06-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 LK06_RS12630 1665b1bf4fac04500da10cb6d0ea7dd2 287 Gene3D G3DSA:3.30.2010.10 59 149 1.1E-30 T 06-07-2017 LK06_RS12630 1665b1bf4fac04500da10cb6d0ea7dd2 287 Pfam PF01435 Peptidase family M48 69 282 4.9E-35 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LK06_RS18665 73ac2282e1cce6c7cf5eac7de180af40 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 1.6E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS18665 73ac2282e1cce6c7cf5eac7de180af40 386 SUPERFAMILY SSF47203 227 384 3.06E-39 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS18665 73ac2282e1cce6c7cf5eac7de180af40 386 SUPERFAMILY SSF56645 5 242 2.88E-61 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS18665 73ac2282e1cce6c7cf5eac7de180af40 386 Gene3D G3DSA:2.40.110.10 122 219 4.4E-26 T 06-07-2017 LK06_RS18665 73ac2282e1cce6c7cf5eac7de180af40 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 117 5.2E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18665 73ac2282e1cce6c7cf5eac7de180af40 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 365 7.4E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS18665 73ac2282e1cce6c7cf5eac7de180af40 386 Gene3D G3DSA:1.10.540.10 6 118 5.2E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18665 73ac2282e1cce6c7cf5eac7de180af40 386 Gene3D G3DSA:1.20.140.10 220 385 4.7E-46 T 06-07-2017 LK06_RS28755 084daa4a9598fb502d06fa2b05a52f0b 371 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 19 361 4.9E-130 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS28755 084daa4a9598fb502d06fa2b05a52f0b 371 Gene3D G3DSA:3.20.20.70 47 213 9.4E-5 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS28755 084daa4a9598fb502d06fa2b05a52f0b 371 PIRSF PIRSF004640 12 371 5.8E-147 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS28755 084daa4a9598fb502d06fa2b05a52f0b 371 SUPERFAMILY SSF56014 278 360 3.75E-11 T 06-07-2017 LK06_RS28755 084daa4a9598fb502d06fa2b05a52f0b 371 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 17 368 33.72 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS28755 084daa4a9598fb502d06fa2b05a52f0b 371 Pfam PF04551 GcpE protein 23 362 5.1E-135 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS28755 084daa4a9598fb502d06fa2b05a52f0b 371 SUPERFAMILY SSF51717 46 221 8.63E-10 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS20890 466fdc930af38c9765a07655d6c8cda7 512 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 06-07-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 LK06_RS20890 466fdc930af38c9765a07655d6c8cda7 512 Pfam PF00221 Aromatic amino acid lyase 12 472 6.1E-180 T 06-07-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 LK06_RS20890 466fdc930af38c9765a07655d6c8cda7 512 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 506 43.174 T 06-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LK06_RS20890 466fdc930af38c9765a07655d6c8cda7 512 Gene3D G3DSA:1.10.275.10 2 198 5.0E-72 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal LK06_RS20890 466fdc930af38c9765a07655d6c8cda7 512 SUPERFAMILY SSF48557 3 503 7.85E-177 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 LK06_RS20890 466fdc930af38c9765a07655d6c8cda7 512 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 506 5.2E-212 T 06-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LK06_RS20890 466fdc930af38c9765a07655d6c8cda7 512 Gene3D G3DSA:1.20.200.10 199 506 2.3E-112 T 06-07-2017 LK06_RS26390 fa6c887263c1f19f9ef979052eff23fe 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 95 3.0E-8 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS26390 fa6c887263c1f19f9ef979052eff23fe 330 SUPERFAMILY SSF51735 120 285 1.12E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26390 fa6c887263c1f19f9ef979052eff23fe 330 Pfam PF00107 Zinc-binding dehydrogenase 157 269 4.2E-15 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS26390 fa6c887263c1f19f9ef979052eff23fe 330 Gene3D G3DSA:3.40.50.720 148 264 2.0E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26390 fa6c887263c1f19f9ef979052eff23fe 330 Gene3D G3DSA:3.90.180.10 3 147 5.4E-36 T 06-07-2017 IPR011032 GroES-like LK06_RS26390 fa6c887263c1f19f9ef979052eff23fe 330 SMART SM00829 10 321 2.4E-12 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS26390 fa6c887263c1f19f9ef979052eff23fe 330 SUPERFAMILY SSF50129 3 149 2.43E-33 T 06-07-2017 IPR011032 GroES-like LK06_RS09985 2644001b943045c488016cde1517650c 193 Pfam PF02632 BioY family 49 188 3.9E-32 T 06-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 LK06_RS09985 2644001b943045c488016cde1517650c 193 PIRSF PIRSF016661 12 193 1.1E-36 T 06-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 LK06_RS21095 37a56eb56a5980f7d44387f54eb2987b 200 SUPERFAMILY SSF52172 2 146 2.99E-13 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS21095 37a56eb56a5980f7d44387f54eb2987b 200 SMART SM00421 131 194 1.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21095 37a56eb56a5980f7d44387f54eb2987b 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 133 178 3.9E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21095 37a56eb56a5980f7d44387f54eb2987b 200 SUPERFAMILY SSF46894 127 179 4.76E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS21095 37a56eb56a5980f7d44387f54eb2987b 200 Pfam PF00072 Response regulator receiver domain 2 93 7.0E-11 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS21095 37a56eb56a5980f7d44387f54eb2987b 200 Gene3D G3DSA:3.40.50.2300 3 136 9.8E-19 T 06-07-2017 LK06_RS21095 37a56eb56a5980f7d44387f54eb2987b 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 134 148 6.4E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21095 37a56eb56a5980f7d44387f54eb2987b 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 164 6.4E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21095 37a56eb56a5980f7d44387f54eb2987b 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 176 6.4E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21095 37a56eb56a5980f7d44387f54eb2987b 200 Gene3D G3DSA:1.10.10.10 137 196 2.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS24870 9f98fdc76da9d52b57bd3e5b3946f252 97 Pfam PF04149 Domain of unknown function (DUF397) 34 79 6.6E-8 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS02225 666e120dd674ece750a3604f67bfc913 408 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 258 402 2.6E-51 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS02225 666e120dd674ece750a3604f67bfc913 408 SUPERFAMILY SSF47203 258 406 1.93E-53 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS02225 666e120dd674ece750a3604f67bfc913 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 115 5.1E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS02225 666e120dd674ece750a3604f67bfc913 408 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 361 380 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS02225 666e120dd674ece750a3604f67bfc913 408 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 1.7E-24 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS02225 666e120dd674ece750a3604f67bfc913 408 Gene3D G3DSA:1.20.140.10 223 406 3.3E-65 T 06-07-2017 LK06_RS02225 666e120dd674ece750a3604f67bfc913 408 Gene3D G3DSA:1.10.540.10 4 115 1.4E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS02225 666e120dd674ece750a3604f67bfc913 408 SUPERFAMILY SSF56645 5 234 3.93E-58 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS02225 666e120dd674ece750a3604f67bfc913 408 Gene3D G3DSA:2.40.110.10 125 222 4.8E-36 T 06-07-2017 LK06_RS26380 5775ad01e7875a3dea9533d44f15a36e 522 Gene3D G3DSA:3.40.50.980 14 182 3.2E-23 T 06-07-2017 LK06_RS26380 5775ad01e7875a3dea9533d44f15a36e 522 Gene3D G3DSA:3.40.50.980 183 331 1.3E-13 T 06-07-2017 LK06_RS26380 5775ad01e7875a3dea9533d44f15a36e 522 SUPERFAMILY SSF56801 12 514 2.22E-65 T 06-07-2017 LK06_RS26380 5775ad01e7875a3dea9533d44f15a36e 522 Gene3D G3DSA:2.30.38.10 348 422 6.7E-12 T 06-07-2017 LK06_RS26380 5775ad01e7875a3dea9533d44f15a36e 522 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS26380 5775ad01e7875a3dea9533d44f15a36e 522 Pfam PF00501 AMP-binding enzyme 17 427 2.7E-49 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS16250 62a4ebd06b4f7d99456d3cce67ece78b 665 Pfam PF05425 Copper resistance protein D 341 422 2.2E-17 T 06-07-2017 IPR008457 Copper resistance protein D GO:0016021 LK06_RS16250 62a4ebd06b4f7d99456d3cce67ece78b 665 Gene3D G3DSA:2.60.40.1220 32 127 1.9E-26 T 06-07-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like LK06_RS16250 62a4ebd06b4f7d99456d3cce67ece78b 665 SUPERFAMILY SSF81296 32 127 4.97E-23 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS16250 62a4ebd06b4f7d99456d3cce67ece78b 665 Pfam PF04234 CopC domain 33 127 5.9E-23 T 06-07-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 LK06_RS28895 66c505a8068359d55274508a2bddbb8a 834 Pfam PF00501 AMP-binding enzyme 491 690 1.5E-7 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS28895 66c505a8068359d55274508a2bddbb8a 834 Gene3D G3DSA:3.40.50.980 553 647 8.4E-9 T 06-07-2017 LK06_RS28895 66c505a8068359d55274508a2bddbb8a 834 Gene3D G3DSA:3.40.605.10 94 276 3.1E-6 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS28895 66c505a8068359d55274508a2bddbb8a 834 Pfam PF05893 Acyl-CoA reductase (LuxC) 41 432 3.9E-83 T 06-07-2017 IPR008670 Acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 LK06_RS28895 66c505a8068359d55274508a2bddbb8a 834 SUPERFAMILY SSF56801 448 794 3.01E-25 T 06-07-2017 LK06_RS28895 66c505a8068359d55274508a2bddbb8a 834 SUPERFAMILY SSF53720 5 293 8.77E-15 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS07580 157c5fa239451c0c473d3f1e17362e8b 344 Pfam PF00877 NlpC/P60 family 244 335 5.6E-25 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS07580 157c5fa239451c0c473d3f1e17362e8b 344 SUPERFAMILY SSF54001 226 336 1.62E-36 T 06-07-2017 LK06_RS07580 157c5fa239451c0c473d3f1e17362e8b 344 Gene3D G3DSA:3.90.1720.10 226 334 3.7E-39 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS07845 96b9757a0876e4b1fa4f53c4291718c8 454 Pfam PF01593 Flavin containing amine oxidoreductase 17 432 1.6E-38 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 LK06_RS07845 96b9757a0876e4b1fa4f53c4291718c8 454 SUPERFAMILY SSF51905 390 435 1.18E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07845 96b9757a0876e4b1fa4f53c4291718c8 454 SUPERFAMILY SSF51905 8 303 1.18E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07845 96b9757a0876e4b1fa4f53c4291718c8 454 Gene3D G3DSA:3.50.50.60 395 436 1.5E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07845 96b9757a0876e4b1fa4f53c4291718c8 454 Gene3D G3DSA:3.50.50.60 8 46 1.5E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07845 96b9757a0876e4b1fa4f53c4291718c8 454 Gene3D G3DSA:3.50.50.60 226 293 1.5E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS16300 7bb27c4ff1af2229ede5ebf5de41fd0b 221 SMART SM00943 26 197 2.1E-28 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal LK06_RS16300 7bb27c4ff1af2229ede5ebf5de41fd0b 221 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 27 189 5.6E-17 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal LK06_RS15750 c6ff6b6a096aa2f6bcbfe3d650a43cb5 252 SMART SM00345 15 74 3.4E-21 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS15750 c6ff6b6a096aa2f6bcbfe3d650a43cb5 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 3.5E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS15750 c6ff6b6a096aa2f6bcbfe3d650a43cb5 252 Gene3D G3DSA:1.10.10.10 6 74 2.2E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15750 c6ff6b6a096aa2f6bcbfe3d650a43cb5 252 Gene3D G3DSA:3.40.1410.10 75 248 3.0E-58 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS15750 c6ff6b6a096aa2f6bcbfe3d650a43cb5 252 Pfam PF07702 UTRA domain 108 244 1.2E-27 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS15750 c6ff6b6a096aa2f6bcbfe3d650a43cb5 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS15750 c6ff6b6a096aa2f6bcbfe3d650a43cb5 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS15750 c6ff6b6a096aa2f6bcbfe3d650a43cb5 252 SMART SM00866 101 245 2.2E-21 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS15750 c6ff6b6a096aa2f6bcbfe3d650a43cb5 252 SUPERFAMILY SSF46785 6 78 1.75E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15750 c6ff6b6a096aa2f6bcbfe3d650a43cb5 252 SUPERFAMILY SSF64288 62 251 6.81E-34 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS27170 b00239ffaf868f44e9995d9d7594b81f 74 SUPERFAMILY SSF55331 2 74 1.27E-14 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily LK06_RS27170 b00239ffaf868f44e9995d9d7594b81f 74 Pfam PF01361 Tautomerase enzyme 2 52 8.1E-10 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 LK06_RS27170 b00239ffaf868f44e9995d9d7594b81f 74 Gene3D G3DSA:3.30.429.20 1 52 1.8E-9 T 06-07-2017 LK06_RS09810 936962cf98e30223d4a0796639957335 106 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 22.842 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09810 936962cf98e30223d4a0796639957335 106 SUPERFAMILY SSF141091 1 101 2.88E-30 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09810 936962cf98e30223d4a0796639957335 106 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 6.7E-27 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09810 936962cf98e30223d4a0796639957335 106 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 101 1.3E-31 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09810 936962cf98e30223d4a0796639957335 106 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 06-07-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS04565 a8e50ba1fab50d37b86655d653d61c2c 410 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 170 381 2.6E-47 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS04565 a8e50ba1fab50d37b86655d653d61c2c 410 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 248 281 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 LK06_RS04565 a8e50ba1fab50d37b86655d653d61c2c 410 SUPERFAMILY SSF51735 7 109 6.89E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS04565 a8e50ba1fab50d37b86655d653d61c2c 410 Pfam PF13241 Putative NAD(P)-binding 11 118 8.0E-19 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 LK06_RS04565 a8e50ba1fab50d37b86655d653d61c2c 410 Gene3D G3DSA:3.30.950.10 284 403 8.0E-44 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS04565 a8e50ba1fab50d37b86655d653d61c2c 410 Gene3D G3DSA:3.40.50.720 7 112 4.3E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS04565 a8e50ba1fab50d37b86655d653d61c2c 410 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 170 404 1.7E-85 T 06-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 LK06_RS04565 a8e50ba1fab50d37b86655d653d61c2c 410 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 8 131 2.8E-18 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 LK06_RS04565 a8e50ba1fab50d37b86655d653d61c2c 410 SUPERFAMILY SSF53790 165 403 1.96E-73 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS04565 a8e50ba1fab50d37b86655d653d61c2c 410 Gene3D G3DSA:3.40.1010.10 170 283 1.1E-40 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS22145 e0c59a050fb6b3aeaec9fe0d9a874ed5 338 Pfam PF12697 Alpha/beta hydrolase family 55 308 8.4E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS22145 e0c59a050fb6b3aeaec9fe0d9a874ed5 338 Gene3D G3DSA:3.40.50.1820 23 313 7.7E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22145 e0c59a050fb6b3aeaec9fe0d9a874ed5 338 SUPERFAMILY SSF53474 29 315 6.72E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08200 5451b77caabdbde7de6845e5829d6893 212 Pfam PF13419 Haloacid dehalogenase-like hydrolase 63 177 2.7E-9 T 06-07-2017 IPR023214 HAD-like domain LK06_RS08200 5451b77caabdbde7de6845e5829d6893 212 Gene3D G3DSA:3.40.50.1000 1 207 1.3E-28 T 06-07-2017 IPR023214 HAD-like domain LK06_RS08200 5451b77caabdbde7de6845e5829d6893 212 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 171 1.7E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS08200 5451b77caabdbde7de6845e5829d6893 212 SUPERFAMILY SSF56784 1 206 2.03E-33 T 06-07-2017 IPR023214 HAD-like domain LK06_RS25180 f6cefd8a6751da20a2a35548125837e4 652 Pfam PF04183 IucA / IucC family 197 426 7.8E-65 T 06-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 LK06_RS25180 f6cefd8a6751da20a2a35548125837e4 652 Pfam PF06276 Ferric iron reductase FhuF-like transporter 472 633 3.5E-30 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain LK06_RS25275 1b2653126d42edd3fe7fff7eb07dbbbe 295 Pfam PF07729 FCD domain 157 279 1.1E-23 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS25275 1b2653126d42edd3fe7fff7eb07dbbbe 295 Gene3D G3DSA:1.10.10.10 60 130 1.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25275 1b2653126d42edd3fe7fff7eb07dbbbe 295 SMART SM00345 70 128 1.1E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS25275 1b2653126d42edd3fe7fff7eb07dbbbe 295 SUPERFAMILY SSF46785 62 132 1.91E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25275 1b2653126d42edd3fe7fff7eb07dbbbe 295 Pfam PF00392 Bacterial regulatory proteins, gntR family 69 128 2.3E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS25275 1b2653126d42edd3fe7fff7eb07dbbbe 295 Gene3D G3DSA:1.20.120.530 154 280 7.1E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS25275 1b2653126d42edd3fe7fff7eb07dbbbe 295 SMART SM00895 157 281 3.4E-22 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS25275 1b2653126d42edd3fe7fff7eb07dbbbe 295 SUPERFAMILY SSF48008 154 280 8.63E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 Gene3D G3DSA:3.90.105.10 162 192 2.7E-18 T 06-07-2017 LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 SUPERFAMILY SSF53218 208 362 3.53E-36 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 SUPERFAMILY SSF63882 14 207 2.88E-50 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 SMART SM00852 211 357 3.2E-40 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 Gene3D G3DSA:2.40.340.10 375 439 7.7E-20 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 208 353 1.9E-30 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 Pfam PF03453 MoeA N-terminal region (domain I and II) 16 198 6.9E-35 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 Gene3D G3DSA:3.40.980.10 193 374 1.1E-57 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 SUPERFAMILY SSF63867 367 439 3.01E-16 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 Gene3D G3DSA:2.170.190.11 57 161 4.2E-33 T 06-07-2017 LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 Pfam PF00994 Probable molybdopterin binding domain 214 356 8.8E-27 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS19375 9a78f740d9d1171d7bff53bf679da3a2 440 Pfam PF03454 MoeA C-terminal region (domain IV) 376 439 8.2E-18 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS26930 0ff705ae1027460b0be48e40702f9e49 294 SUPERFAMILY SSF161098 86 274 5.76E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26930 0ff705ae1027460b0be48e40702f9e49 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 276 2.1E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26930 0ff705ae1027460b0be48e40702f9e49 294 Gene3D G3DSA:1.10.3720.10 87 276 8.0E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 Hamap MF_00015 LexA repressor [lexA]. 52 259 34.283 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 175 185 2.4E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 214 226 2.4E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 186 197 2.4E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 SUPERFAMILY SSF46785 52 118 2.96E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 TIGRFAM TIGR00498 lexA: repressor LexA 51 259 1.3E-75 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 Pfam PF00717 Peptidase S24-like 178 243 1.2E-16 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 Pfam PF01726 LexA DNA binding domain 51 114 1.0E-29 T 06-07-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 Gene3D G3DSA:1.10.10.10 52 118 1.8E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 SUPERFAMILY SSF51306 139 257 5.41E-37 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C LK06_RS25195 e2fc896b5c18d2954235019dfab7ccc6 259 Gene3D G3DSA:2.10.109.10 140 258 4.5E-45 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS13370 40b8c6ad45de4b51180821fab3aeab63 300 PIRSF PIRSF017393 3 300 4.9E-95 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS13370 40b8c6ad45de4b51180821fab3aeab63 300 Pfam PF04672 S-adenosyl methyltransferase 11 300 2.5E-110 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS13370 40b8c6ad45de4b51180821fab3aeab63 300 Gene3D G3DSA:3.40.50.150 9 299 8.1E-106 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS13370 40b8c6ad45de4b51180821fab3aeab63 300 SUPERFAMILY SSF53335 21 261 5.87E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS02220 002c364b4495a88bb4bf30499a15ab6e 299 SUPERFAMILY SSF51445 18 152 2.74E-10 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS02220 002c364b4495a88bb4bf30499a15ab6e 299 Gene3D G3DSA:3.20.20.80 17 165 3.4E-18 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS02220 002c364b4495a88bb4bf30499a15ab6e 299 Pfam PF08924 Domain of unknown function (DUF1906) 16 129 1.5E-20 T 06-07-2017 IPR015020 Protein of unknown function DUF1906 LK06_RS10945 470a4058d4d9721d2f9e5a56d50d4589 298 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 54 268 1.0E-40 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LK06_RS10945 470a4058d4d9721d2f9e5a56d50d4589 298 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 33 296 1.2E-65 T 06-07-2017 IPR014337 Ectoine/Hydroxyectoine-binding protein EhuB GO:0005886|GO:0033294|GO:0051470|GO:0051471 LK06_RS10945 470a4058d4d9721d2f9e5a56d50d4589 298 SUPERFAMILY SSF53850 55 278 1.04E-39 T 06-07-2017 LK06_RS10945 470a4058d4d9721d2f9e5a56d50d4589 298 Gene3D G3DSA:3.40.190.10 128 226 4.8E-11 T 06-07-2017 LK06_RS10945 470a4058d4d9721d2f9e5a56d50d4589 298 Gene3D G3DSA:3.40.190.10 236 268 6.5E-21 T 06-07-2017 LK06_RS10945 470a4058d4d9721d2f9e5a56d50d4589 298 Gene3D G3DSA:3.40.190.10 48 127 6.5E-21 T 06-07-2017 LK06_RS10945 470a4058d4d9721d2f9e5a56d50d4589 298 SMART SM00062 52 282 3.2E-31 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LK06_RS23655 f96c8e663d47587924e8fc6a10fc9d61 608 Gene3D G3DSA:1.20.1560.10 19 330 8.7E-69 T 06-07-2017 LK06_RS23655 f96c8e663d47587924e8fc6a10fc9d61 608 ProSitePatterns PS00211 ABC transporters family signature. 505 519 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS23655 f96c8e663d47587924e8fc6a10fc9d61 608 SUPERFAMILY SSF90123 19 336 6.8E-72 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS23655 f96c8e663d47587924e8fc6a10fc9d61 608 SMART SM00382 393 573 5.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS23655 f96c8e663d47587924e8fc6a10fc9d61 608 Gene3D G3DSA:3.40.50.300 364 597 5.0E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23655 f96c8e663d47587924e8fc6a10fc9d61 608 SUPERFAMILY SSF52540 361 601 3.4E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23655 f96c8e663d47587924e8fc6a10fc9d61 608 Pfam PF00005 ABC transporter 384 532 5.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS23655 f96c8e663d47587924e8fc6a10fc9d61 608 Pfam PF00664 ABC transporter transmembrane region 32 302 1.6E-41 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 5.9E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 5.9E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 5.9E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 Gene3D G3DSA:3.90.930.12 84 178 8.6E-38 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.061 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 SUPERFAMILY SSF56053 84 177 4.44E-35 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 Pfam PF00347 Ribosomal protein L6 11 83 4.9E-19 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 Pfam PF00347 Ribosomal protein L6 92 165 9.1E-20 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 SUPERFAMILY SSF56053 1 83 5.76E-26 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 06-07-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 PIRSF PIRSF002162 1 178 4.1E-46 T 06-07-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 1.5E-72 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 LK06_RS12235 05dc0f91978e9eceb8004682fec291ae 179 Gene3D G3DSA:3.90.930.12 2 83 1.2E-29 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Gene3D G3DSA:3.50.30.10 407 511 4.7E-38 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Gene3D G3DSA:3.30.1490.20 206 249 4.1E-58 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Gene3D G3DSA:3.30.1490.20 11 117 4.1E-58 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Pfam PF00391 PEP-utilising enzyme, mobile domain 426 508 1.1E-25 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 SUPERFAMILY SSF51621 544 896 1.39E-112 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 SUPERFAMILY SSF52009 395 517 3.66E-34 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 PIRSF PIRSF000853 9 906 0.0 T 06-07-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Gene3D G3DSA:1.10.189.10 348 406 1.3E-23 T 06-07-2017 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 454 465 - T 06-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 301 357 5.5E-10 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 25 293 9.2E-42 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Gene3D G3DSA:1.20.80.30 118 204 1.8E-35 T 06-07-2017 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Gene3D G3DSA:3.30.470.20 250 347 1.5E-34 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Gene3D G3DSA:3.20.20.60 555 899 1.4E-126 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 11 897 0.0 T 06-07-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 542 894 1.7E-84 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 LK06_RS09245 f76d3ab21994a7ed25fff46668b020c8 906 SUPERFAMILY SSF56059 10 383 7.3E-135 T 06-07-2017 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 650 1.5E-197 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 189 235 3.0E-14 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 SMART SM00863 179 235 1.8E-21 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 654 33.287 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 Pfam PF03129 Anticodon binding domain 561 649 2.1E-19 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 SUPERFAMILY SSF55681 259 546 1.01E-90 T 06-07-2017 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 527 540 6.8E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 348 376 6.8E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 381 404 6.8E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 484 512 6.8E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 554 566 6.8E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 Gene3D G3DSA:3.40.50.800 551 656 9.5E-32 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 Gene3D G3DSA:3.30.930.10 258 550 1.7E-103 T 06-07-2017 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 SUPERFAMILY SSF52954 549 654 1.31E-28 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 Gene3D G3DSA:3.30.54.20 131 203 5.5E-11 T 06-07-2017 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 342 549 1.7E-36 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 SUPERFAMILY SSF55186 64 257 7.19E-55 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 Gene3D G3DSA:3.30.980.10 66 129 2.9E-43 T 06-07-2017 LK06_RS04355 ba19b8e88bf26e1a3efd174e6a7a941f 658 Gene3D G3DSA:3.30.980.10 204 240 2.9E-43 T 06-07-2017 LK06_RS26775 6c90acb8268648046989431bb349cf39 158 SUPERFAMILY SSF103196 22 141 8.02E-26 T 06-07-2017 LK06_RS26775 6c90acb8268648046989431bb349cf39 158 Gene3D G3DSA:3.30.450.30 20 140 2.9E-20 T 06-07-2017 LK06_RS26775 6c90acb8268648046989431bb349cf39 158 Pfam PF03259 Roadblock/LC7 domain 27 116 5.7E-17 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS26775 6c90acb8268648046989431bb349cf39 158 SMART SM00960 26 116 5.1E-23 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS13800 7d2e48dd72df88de679d05c49c4750ef 679 SUPERFAMILY SSF140990 421 619 3.79E-74 T 06-07-2017 LK06_RS13800 7d2e48dd72df88de679d05c49c4750ef 679 Pfam PF01434 Peptidase family M41 402 609 6.1E-81 T 06-07-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 LK06_RS13800 7d2e48dd72df88de679d05c49c4750ef 679 SMART SM00382 203 342 1.1E-23 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS13800 7d2e48dd72df88de679d05c49c4750ef 679 Gene3D G3DSA:3.40.50.300 163 347 2.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13800 7d2e48dd72df88de679d05c49c4750ef 679 Gene3D G3DSA:1.10.8.60 348 414 5.5E-24 T 06-07-2017 LK06_RS13800 7d2e48dd72df88de679d05c49c4750ef 679 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 LK06_RS13800 7d2e48dd72df88de679d05c49c4750ef 679 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 120 610 4.7E-232 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 LK06_RS13800 7d2e48dd72df88de679d05c49c4750ef 679 SUPERFAMILY SSF52540 161 411 4.68E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13800 7d2e48dd72df88de679d05c49c4750ef 679 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 338 1.8E-43 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS13800 7d2e48dd72df88de679d05c49c4750ef 679 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 619 36.966 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 217 1.4E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 SUPERFAMILY SSF46894 156 222 2.69E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 Gene3D G3DSA:1.10.10.10 163 222 4.6E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 Gene3D G3DSA:3.40.50.2300 6 162 3.1E-35 T 06-07-2017 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 Pfam PF00072 Response regulator receiver domain 10 120 7.8E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 SMART SM00421 160 217 2.7E-26 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 SMART SM00448 8 120 2.0E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 7.3E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 7.3E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 7.3E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07490 cbb68ab956838dd0c817acc03798c880 225 SUPERFAMILY SSF52172 6 124 2.56E-31 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 SUPERFAMILY SSF50249 384 504 3.26E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 208 216 - T 06-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 Gene3D G3DSA:2.40.50.140 385 504 2.4E-33 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 Pfam PF04675 DNA ligase N terminus 70 137 4.7E-7 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 Hamap MF_00407 DNA ligase [lig]. 1 508 26.245 T 06-07-2017 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 Pfam PF04679 ATP dependent DNA ligase C terminal region 401 492 2.9E-14 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 Gene3D G3DSA:3.30.470.30 213 326 5.5E-27 T 06-07-2017 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 Gene3D G3DSA:3.30.1490.70 331 378 8.7E-19 T 06-07-2017 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 Gene3D G3DSA:3.30.1490.70 184 212 8.7E-19 T 06-07-2017 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 Pfam PF01068 ATP dependent DNA ligase domain 186 382 2.2E-44 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 SUPERFAMILY SSF117018 5 202 1.22E-27 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 SUPERFAMILY SSF56091 180 382 1.06E-45 T 06-07-2017 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 Gene3D G3DSA:1.10.3260.10 70 183 1.7E-18 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 LK06_RS02185 8270765d0cd80169dd78f3c031bacadb 512 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 69 502 4.9E-81 T 06-07-2017 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 LK06_RS23645 b395504e46fb22b96fdc2603be2067fb 173 PIRSF PIRSF010260 2 169 1.8E-71 T 06-07-2017 IPR014457 Uncharacterised conserved protein UCP010260 LK06_RS23645 b395504e46fb22b96fdc2603be2067fb 173 Pfam PF09348 Domain of unknown function (DUF1990) 7 160 5.2E-52 T 06-07-2017 IPR018960 Domain of unknown function DUF1990 LK06_RS02770 76010f26fd75a131e241e9a861d118c4 303 SUPERFAMILY SSF55347 135 270 2.62E-39 T 06-07-2017 LK06_RS02770 76010f26fd75a131e241e9a861d118c4 303 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 303 63.858 T 06-07-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 LK06_RS02770 76010f26fd75a131e241e9a861d118c4 303 Gene3D G3DSA:3.40.50.720 12 147 2.8E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02770 76010f26fd75a131e241e9a861d118c4 303 SUPERFAMILY SSF51735 15 161 4.23E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02770 76010f26fd75a131e241e9a861d118c4 303 PIRSF PIRSF015689 9 300 2.9E-104 T 06-07-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 LK06_RS02770 76010f26fd75a131e241e9a861d118c4 303 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 135 270 7.0E-37 T 06-07-2017 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 LK06_RS02770 76010f26fd75a131e241e9a861d118c4 303 Gene3D G3DSA:3.30.360.10 148 253 3.3E-35 T 06-07-2017 LK06_RS02770 76010f26fd75a131e241e9a861d118c4 303 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 15 124 1.1E-5 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.40.50.980 2665 2813 2.4E-34 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.40.50.980 596 751 5.3E-47 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.40.50.980 1647 1782 2.4E-26 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3028 3043 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF00668 Condensation domain 1032 1324 1.7E-53 T 06-07-2017 IPR001242 Condensation domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF00668 Condensation domain 7 293 1.9E-56 T 06-07-2017 IPR001242 Condensation domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF00668 Condensation domain 2075 2365 1.9E-54 T 06-07-2017 IPR001242 Condensation domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF00501 AMP-binding enzyme 1495 1884 1.7E-82 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF00501 AMP-binding enzyme 457 843 2.4E-97 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF00501 AMP-binding enzyme 2531 2901 1.1E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF13745 HxxPF-repeated domain 2387 2476 4.8E-30 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF13745 HxxPF-repeated domain 1346 1442 3.5E-30 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2655 2666 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1637 1648 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF56801 416 962 1.23E-154 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.30.300.30 2897 3008 1.6E-27 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.30.300.30 1879 1992 2.0E-37 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.30.300.30 839 953 2.2E-29 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF52777 2254 2516 9.12E-60 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF53474 3072 3326 2.7E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.40.50.1820 3264 3329 2.0E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.40.50.1820 3076 3192 2.0E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2012 2027 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF00550 Phosphopantetheine attachment site 1989 2053 7.6E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF00550 Phosphopantetheine attachment site 952 1014 3.1E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF00550 Phosphopantetheine attachment site 3006 3069 8.8E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF52777 1035 1200 3.0E-46 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.40.50.980 2525 2664 6.5E-48 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.40.50.980 451 595 6.8E-45 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:3.40.50.980 1489 1646 5.9E-44 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF47336 1983 2054 9.81E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SMART SM00824 Thioesterase 3091 3325 9.7E-4 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 ProSitePatterns PS00012 Phosphopantetheine attachment site. 973 988 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF00975 Thioesterase domain 3089 3321 4.3E-23 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF52777 1213 1480 1.33E-59 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 ProSitePatterns PS00455 Putative AMP-binding domain signature. 587 598 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF52777 2078 2241 9.12E-47 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:1.10.1200.10 3009 3073 4.4E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:1.10.1200.10 954 1017 1.9E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:1.10.1200.10 1993 2056 2.6E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF56801 2491 3016 1.96E-149 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF47336 943 1014 7.59E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1516 1908 2.4E-119 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 477 867 4.8E-128 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2552 2924 4.6E-125 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF52777 182 443 2.89E-55 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SMART SM00823 Phosphopantetheine attachment site 1988 2057 1.1E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SMART SM00823 Phosphopantetheine attachment site 949 1018 1.0E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SMART SM00823 Phosphopantetheine attachment site 3004 3073 0.0052 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF52777 6 197 1.09E-42 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF47336 2998 3070 3.01E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF13193 AMP-binding enzyme C-terminal domain 2909 2979 3.0E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF13193 AMP-binding enzyme C-terminal domain 1892 1964 8.2E-13 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Pfam PF13193 AMP-binding enzyme C-terminal domain 851 924 7.5E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:2.30.38.10 2814 2891 9.6E-30 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:2.30.38.10 753 832 4.3E-25 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 Gene3D G3DSA:2.30.38.10 1794 1874 7.0E-24 T 06-07-2017 LK06_RS21040 1d02ab89e8fb7e229fe827b0adf05627 3341 SUPERFAMILY SSF56801 1455 2001 2.35E-141 T 06-07-2017 LK06_RS18900 e7415d1bf7f34db4d94094c8e878c881 194 Gene3D G3DSA:1.10.357.10 7 184 6.4E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS18900 e7415d1bf7f34db4d94094c8e878c881 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 1.4E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS18900 e7415d1bf7f34db4d94094c8e878c881 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 7.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS18900 e7415d1bf7f34db4d94094c8e878c881 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 7.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS18900 e7415d1bf7f34db4d94094c8e878c881 194 SUPERFAMILY SSF46689 12 80 1.5E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS18900 e7415d1bf7f34db4d94094c8e878c881 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 64 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS23305 c30411277f877542727cfe5515be52da 478 SUPERFAMILY SSF52540 92 362 2.03E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23305 c30411277f877542727cfe5515be52da 478 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 144 357 1.4E-64 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23305 c30411277f877542727cfe5515be52da 478 SUPERFAMILY SSF50615 10 90 3.92E-26 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23305 c30411277f877542727cfe5515be52da 478 Gene3D G3DSA:3.40.50.300 91 359 4.3E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23305 c30411277f877542727cfe5515be52da 478 Gene3D G3DSA:1.10.1140.10 360 475 3.1E-43 T 06-07-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23305 c30411277f877542727cfe5515be52da 478 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 14 88 7.7E-23 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23305 c30411277f877542727cfe5515be52da 478 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 348 357 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23305 c30411277f877542727cfe5515be52da 478 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 11 475 2.3E-236 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 LK06_RS23305 c30411277f877542727cfe5515be52da 478 SUPERFAMILY SSF47917 360 475 6.02E-45 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23305 c30411277f877542727cfe5515be52da 478 Gene3D G3DSA:2.40.10.170 5 90 6.3E-31 T 06-07-2017 LK06_RS23305 c30411277f877542727cfe5515be52da 478 SMART SM00382 156 342 3.2E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS23305 c30411277f877542727cfe5515be52da 478 Hamap MF_01347 ATP synthase subunit beta [atpB]. 9 475 54.639 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 SUPERFAMILY SSF158472 194 244 5.89E-6 T 06-07-2017 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 311 4.3E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 SUPERFAMILY SSF55874 314 463 5.11E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 SMART SM00388 248 315 8.3E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 Pfam PF00672 HAMP domain 175 243 2.3E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 4.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 4.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 4.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 SMART SM00387 355 468 2.5E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 SUPERFAMILY SSF47384 231 312 6.08E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 Gene3D G3DSA:1.10.287.130 238 301 1.2E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 463 1.4E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 SMART SM00304 194 247 7.6E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS13300 3a162808320b3663cacf9f4c052cfc2b 478 Gene3D G3DSA:3.30.565.10 302 462 1.1E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS27935 13b850ef0290d8638e82ba7bfe3075b8 173 SUPERFAMILY SSF53155 4 83 2.47E-14 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 LK06_RS27935 13b850ef0290d8638e82ba7bfe3075b8 173 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 158 7.1E-34 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LK06_RS27935 13b850ef0290d8638e82ba7bfe3075b8 173 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 157 9.3E-36 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LK06_RS27935 13b850ef0290d8638e82ba7bfe3075b8 173 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 2 160 38.857 T 06-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 LK06_RS27935 13b850ef0290d8638e82ba7bfe3075b8 173 SUPERFAMILY SSF46767 77 158 2.35E-33 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LK06_RS27935 13b850ef0290d8638e82ba7bfe3075b8 173 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 LK06_RS27935 13b850ef0290d8638e82ba7bfe3075b8 173 Gene3D G3DSA:1.10.10.10 76 159 4.6E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27935 13b850ef0290d8638e82ba7bfe3075b8 173 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 4 74 6.0E-10 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 Pfam PF00089 Trypsin 195 353 1.1E-12 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 Gene3D G3DSA:3.30.300.50 100 166 1.7E-5 T 06-07-2017 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 Gene3D G3DSA:2.40.10.10 258 348 1.9E-31 T 06-07-2017 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 311 322 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 283 300 9.8E-43 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 326 340 9.8E-43 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 302 325 9.8E-43 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 262 282 9.8E-43 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 198 212 9.8E-43 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 Gene3D G3DSA:3.30.300.50 48 98 1.4E-5 T 06-07-2017 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 Gene3D G3DSA:2.40.10.10 173 248 1.1E-24 T 06-07-2017 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 Pfam PF02983 Alpha-lytic protease prodomain 100 154 3.1E-14 T 06-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 SUPERFAMILY SSF50494 176 355 6.35E-35 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS00910 5d6b713d6a1e01dc8d4c4415d9307b08 457 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 200 205 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 LK06_RS23585 40dbad29fb4d7d99b850178b4335162d 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 60 5.8E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23585 40dbad29fb4d7d99b850178b4335162d 207 Gene3D G3DSA:1.10.10.60 5 43 1.3E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS23585 40dbad29fb4d7d99b850178b4335162d 207 Gene3D G3DSA:1.10.357.10 44 179 6.9E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS23585 40dbad29fb4d7d99b850178b4335162d 207 SUPERFAMILY SSF48498 87 163 3.05E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS23585 40dbad29fb4d7d99b850178b4335162d 207 SUPERFAMILY SSF46689 7 87 1.45E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS28915 cd0f055e0b6cb819e5fac722a2374f19 270 SUPERFAMILY SSF53335 17 252 1.35E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28915 cd0f055e0b6cb819e5fac722a2374f19 270 PIRSF PIRSF017393 2 270 1.8E-97 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS28915 cd0f055e0b6cb819e5fac722a2374f19 270 Gene3D G3DSA:3.40.50.150 7 270 1.3E-105 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28915 cd0f055e0b6cb819e5fac722a2374f19 270 Pfam PF04672 S-adenosyl methyltransferase 9 268 1.1E-100 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS27945 b10b84bd5c01864b5c5c844c160bb273 245 Gene3D G3DSA:3.30.1600.10 113 160 6.6E-23 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain LK06_RS27945 b10b84bd5c01864b5c5c844c160bb273 245 Gene3D G3DSA:3.30.1600.10 22 61 6.6E-23 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain LK06_RS27945 b10b84bd5c01864b5c5c844c160bb273 245 Gene3D G3DSA:3.40.50.1220 167 240 1.3E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS27945 b10b84bd5c01864b5c5c844c160bb273 245 Gene3D G3DSA:3.40.50.1220 73 112 1.3E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS27945 b10b84bd5c01864b5c5c844c160bb273 245 Gene3D G3DSA:3.40.50.1220 6 21 1.3E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS27945 b10b84bd5c01864b5c5c844c160bb273 245 Pfam PF02146 Sir2 family 11 191 2.8E-45 T 06-07-2017 IPR003000 Sirtuin family GO:0070403 LK06_RS27945 b10b84bd5c01864b5c5c844c160bb273 245 SUPERFAMILY SSF52467 6 239 1.26E-73 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 SUPERFAMILY SSF52540 408 625 4.51E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 SUPERFAMILY SSF81886 627 851 3.79E-74 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 827 0.0 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 SMART SM00958 226 350 4.6E-64 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 Gene3D G3DSA:3.40.50.300 3 226 2.5E-123 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 Gene3D G3DSA:3.40.50.300 361 408 2.5E-123 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 Gene3D G3DSA:3.40.50.300 409 626 3.9E-94 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 Pfam PF07516 SecA Wing and Scaffold domain 624 838 2.3E-66 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 PRINTS PR00906 SecA protein signature 115 125 6.3E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 PRINTS PR00906 SecA protein signature 405 418 6.3E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 PRINTS PR00906 SecA protein signature 168 188 6.3E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 PRINTS PR00906 SecA protein signature 331 353 6.3E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 PRINTS PR00906 SecA protein signature 99 113 6.3E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 PRINTS PR00906 SecA protein signature 61 85 6.3E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 PRINTS PR00906 SecA protein signature 368 385 6.3E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 ProSitePatterns PS01312 SecA family signature. 492 507 - T 06-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 SUPERFAMILY SSF81767 225 360 1.7E-40 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 Pfam PF07517 SecA DEAD-like domain 5 393 1.2E-129 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 SMART SM00957 4 394 1.5E-280 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 Gene3D G3DSA:3.90.1440.10 228 360 3.5E-44 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 Pfam PF01043 SecA preprotein cross-linking domain 231 350 6.8E-34 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 SUPERFAMILY SSF52540 360 407 2.66E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 SUPERFAMILY SSF52540 4 226 2.66E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 841 19.976 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LK06_RS11730 d4fa473cc912f86319d6a83caeaad423 936 Gene3D G3DSA:1.10.3060.10 655 839 6.0E-59 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 LK06_RS19295 2b452e5672f910bc71f1b23a875646f1 337 Pfam PF13280 WYL domain 149 318 3.5E-24 T 06-07-2017 IPR026881 WYL domain LK06_RS19295 2b452e5672f910bc71f1b23a875646f1 337 PIRSF PIRSF016838 5 329 2.7E-25 T 06-07-2017 IPR028349 Protein PafC LK06_RS19295 2b452e5672f910bc71f1b23a875646f1 337 Gene3D G3DSA:1.10.10.10 7 70 3.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19295 2b452e5672f910bc71f1b23a875646f1 337 SUPERFAMILY SSF46785 11 69 1.03E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19295 2b452e5672f910bc71f1b23a875646f1 337 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 LK06_RS19295 2b452e5672f910bc71f1b23a875646f1 337 Pfam PF08279 HTH domain 12 67 1.5E-18 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 LK06_RS29015 854eb5e5c2c56c00c38dd8e8a5a36da2 276 Gene3D G3DSA:3.40.50.300 1 198 2.5E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29015 854eb5e5c2c56c00c38dd8e8a5a36da2 276 Pfam PF00005 ABC transporter 1 136 1.2E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS29015 854eb5e5c2c56c00c38dd8e8a5a36da2 276 SUPERFAMILY SSF52540 1 200 1.71E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29015 854eb5e5c2c56c00c38dd8e8a5a36da2 276 SMART SM00382 7 185 1.1E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS28060 74c9997ec6917b746c273e6114779a0f 183 Gene3D G3DSA:3.40.630.30 11 177 1.5E-42 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS28060 74c9997ec6917b746c273e6114779a0f 183 SUPERFAMILY SSF55729 11 176 1.87E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS28060 74c9997ec6917b746c273e6114779a0f 183 Pfam PF13302 Acetyltransferase (GNAT) domain 14 152 8.3E-18 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS10550 0de4fcdf6bd01023623807409a001ae7 297 SUPERFAMILY SSF46785 122 195 4.69E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS10550 0de4fcdf6bd01023623807409a001ae7 297 Gene3D G3DSA:1.10.10.10 129 197 5.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS10550 0de4fcdf6bd01023623807409a001ae7 297 Gene3D G3DSA:1.10.10.10 13 80 7.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS10550 0de4fcdf6bd01023623807409a001ae7 297 Pfam PF00392 Bacterial regulatory proteins, gntR family 129 191 1.6E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS10550 0de4fcdf6bd01023623807409a001ae7 297 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 3.6E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS10550 0de4fcdf6bd01023623807409a001ae7 297 SMART SM00345 132 191 4.4E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS10550 0de4fcdf6bd01023623807409a001ae7 297 SMART SM00345 16 75 7.5E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS10550 0de4fcdf6bd01023623807409a001ae7 297 SUPERFAMILY SSF46785 8 81 3.1E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS10550 0de4fcdf6bd01023623807409a001ae7 297 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.7E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS10550 0de4fcdf6bd01023623807409a001ae7 297 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.7E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS06540 aa1c11af048c05cfe271015400cb67af 372 ProSitePatterns PS01054 Transaldolase signature 1. 41 49 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 LK06_RS06540 aa1c11af048c05cfe271015400cb67af 372 Hamap MF_00493 Transaldolase [tal]. 1 370 160.815 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 LK06_RS06540 aa1c11af048c05cfe271015400cb67af 372 Gene3D G3DSA:3.20.20.70 1 359 1.0E-123 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS06540 aa1c11af048c05cfe271015400cb67af 372 SUPERFAMILY SSF51569 2 359 3.66E-76 T 06-07-2017 LK06_RS06540 aa1c11af048c05cfe271015400cb67af 372 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 359 4.4E-135 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 LK06_RS06540 aa1c11af048c05cfe271015400cb67af 372 Pfam PF00923 Transaldolase 15 359 4.7E-83 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 LK06_RS06540 aa1c11af048c05cfe271015400cb67af 372 PIRSF PIRSF036915 1 372 9.5E-178 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 LK06_RS15550 87e77699c5bba809a08d47d88910d180 110 SUPERFAMILY SSF47413 25 86 1.45E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS15550 87e77699c5bba809a08d47d88910d180 110 SMART SM00530 12 80 1.7E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS15550 87e77699c5bba809a08d47d88910d180 110 Gene3D G3DSA:1.10.260.40 31 82 2.1E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS15550 87e77699c5bba809a08d47d88910d180 110 Pfam PF01381 Helix-turn-helix 33 76 3.1E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS26190 47a168f2cfa394f80666cbd4755c2c24 225 Pfam PF00581 Rhodanese-like domain 125 214 1.9E-11 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS26190 47a168f2cfa394f80666cbd4755c2c24 225 SMART SM00450 123 218 9.3E-16 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS26190 47a168f2cfa394f80666cbd4755c2c24 225 SUPERFAMILY SSF46785 14 120 7.74E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26190 47a168f2cfa394f80666cbd4755c2c24 225 ProSitePatterns PS00380 Rhodanese signature 1. 147 158 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 LK06_RS26190 47a168f2cfa394f80666cbd4755c2c24 225 Pfam PF12840 Helix-turn-helix domain 19 76 1.5E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26190 47a168f2cfa394f80666cbd4755c2c24 225 SMART SM00418 19 97 3.9E-24 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS26190 47a168f2cfa394f80666cbd4755c2c24 225 Gene3D G3DSA:1.10.10.10 6 101 9.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26190 47a168f2cfa394f80666cbd4755c2c24 225 SUPERFAMILY SSF52821 120 221 7.46E-26 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS26190 47a168f2cfa394f80666cbd4755c2c24 225 Gene3D G3DSA:3.40.250.10 119 219 1.0E-21 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 Gene3D G3DSA:3.40.50.720 28 214 4.3E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 30 513 6.5E-201 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 354 380 3.3E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 265 281 3.3E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 195 223 3.3E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 171 184 3.3E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 247 264 3.3E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 Gene3D G3DSA:3.30.360.10 215 512 7.8E-123 T 06-07-2017 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 SUPERFAMILY SSF51735 18 218 1.04E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 32 215 5.3E-62 T 06-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 205 211 - T 06-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 PIRSF PIRSF000110 15 514 1.4E-179 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 SUPERFAMILY SSF55347 205 512 1.7E-114 T 06-07-2017 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 28 513 88.452 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS06545 4d3aaa2ca5253f3a0eb3fc58706f16ac 514 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 217 512 3.7E-115 T 06-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 473 499 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 304 317 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 Gene3D G3DSA:1.10.10.10 353 404 3.9E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 276 512 9.0E-113 T 06-07-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 PRINTS PR00046 Major sigma-70 factor signature 452 464 6.8E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 PRINTS PR00046 Major sigma-70 factor signature 473 488 6.8E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 PRINTS PR00046 Major sigma-70 factor signature 304 317 6.8E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 PRINTS PR00046 Major sigma-70 factor signature 328 336 6.8E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 PRINTS PR00046 Major sigma-70 factor signature 488 499 6.8E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 Gene3D G3DSA:1.10.10.10 442 513 2.0E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 Pfam PF04542 Sigma-70 region 2 280 349 3.1E-22 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 SUPERFAMILY SSF88659 411 512 2.62E-27 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 SUPERFAMILY SSF88659 353 426 3.92E-21 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 Gene3D G3DSA:1.10.601.10 133 349 8.3E-70 T 06-07-2017 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 Pfam PF04539 Sigma-70 region 3 359 435 1.1E-28 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 SUPERFAMILY SSF88946 212 350 7.72E-54 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 Pfam PF04545 Sigma-70, region 4 448 501 2.9E-18 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 276 501 2.0E-36 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 Pfam PF00140 Sigma-70 factor, region 1.2 215 248 8.0E-17 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25280 0c9f2d17ac58ab6a0312ad17760176db 513 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 127 513 31.705 T 06-07-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 LK06_RS21935 d154364159dc50da7e580a14b8173f9e 309 Gene3D G3DSA:3.40.50.300 6 230 7.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21935 d154364159dc50da7e580a14b8173f9e 309 SMART SM00382 38 214 3.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS21935 d154364159dc50da7e580a14b8173f9e 309 SUPERFAMILY SSF52540 7 230 4.52E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21935 d154364159dc50da7e580a14b8173f9e 309 Pfam PF00005 ABC transporter 30 165 8.2E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS21935 d154364159dc50da7e580a14b8173f9e 309 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS17100 a697561d19dcb92f430456f0dea82c3f 506 SUPERFAMILY SSF56300 245 436 4.45E-28 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS17100 a697561d19dcb92f430456f0dea82c3f 506 Gene3D G3DSA:3.60.21.10 249 437 1.6E-19 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS17100 a697561d19dcb92f430456f0dea82c3f 506 Pfam PF00149 Calcineurin-like phosphoesterase 250 417 5.5E-14 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 LK06_RS17720 6ff8be9478a45704194588dec9f9ccba 680 Gene3D G3DSA:3.40.50.300 534 675 2.7E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17720 6ff8be9478a45704194588dec9f9ccba 680 Pfam PF13245 Part of AAA domain 192 262 5.5E-13 T 06-07-2017 LK06_RS17720 6ff8be9478a45704194588dec9f9ccba 680 SUPERFAMILY SSF52540 369 396 1.11E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17720 6ff8be9478a45704194588dec9f9ccba 680 SUPERFAMILY SSF52540 448 677 1.11E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17720 6ff8be9478a45704194588dec9f9ccba 680 SUPERFAMILY SSF52540 175 254 1.11E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17720 6ff8be9478a45704194588dec9f9ccba 680 Gene3D G3DSA:3.40.50.300 182 250 2.9E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17720 6ff8be9478a45704194588dec9f9ccba 680 Gene3D G3DSA:3.40.50.300 401 533 2.9E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 SUPERFAMILY SSF56784 310 601 1.35E-34 T 06-07-2017 IPR023214 HAD-like domain LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 583 608 6.7E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 417 435 6.7E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 552 568 6.7E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 Gene3D G3DSA:3.40.1110.10 353 440 2.4E-5 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 571 5.7E-23 T 06-07-2017 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 575 587 5.7E-23 T 06-07-2017 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 314 328 5.7E-23 T 06-07-2017 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 163 177 5.7E-23 T 06-07-2017 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 476 486 5.7E-23 T 06-07-2017 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 Gene3D G3DSA:2.70.150.10 24 59 1.2E-21 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 Gene3D G3DSA:2.70.150.10 111 211 1.2E-21 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 Pfam PF00122 E1-E2 ATPase 85 305 4.0E-49 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 331 1.1E-27 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 525 640 5.7E-26 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 Pfam PF00702 haloacid dehalogenase-like hydrolase 310 566 7.7E-16 T 06-07-2017 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 Gene3D G3DSA:1.20.1110.10 521 791 3.8E-54 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 Gene3D G3DSA:1.20.1110.10 84 110 3.8E-54 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 Gene3D G3DSA:3.40.1110.10 304 334 3.3E-5 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 316 322 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 SUPERFAMILY SSF81653 119 210 2.35E-19 T 06-07-2017 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 SUPERFAMILY SSF81665 214 308 1.23E-62 T 06-07-2017 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 SUPERFAMILY SSF81665 23 116 1.23E-62 T 06-07-2017 LK06_RS18545 13e8b117f7c9eb908c9b92f2601e7cc5 798 SUPERFAMILY SSF81665 601 796 1.23E-62 T 06-07-2017 LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 588 598 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 Gene3D G3DSA:2.60.120.380 946 1031 2.9E-8 T 06-07-2017 LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 955 1020 1.3E-9 T 06-07-2017 IPR007280 Peptidase, C-terminal, archaeal/bacterial LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 Gene3D G3DSA:3.40.50.200 197 251 9.2E-68 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 Gene3D G3DSA:3.40.50.200 394 649 9.2E-68 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 Pfam PF00082 Subtilase family 205 630 2.9E-56 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 SUPERFAMILY SSF52743 193 225 7.99E-54 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 SUPERFAMILY SSF52743 393 649 7.99E-54 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 PRINTS PR00723 Subtilisin serine protease family (S8) signature 587 603 1.1E-15 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 PRINTS PR00723 Subtilisin serine protease family (S8) signature 390 403 1.1E-15 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 PRINTS PR00723 Subtilisin serine protease family (S8) signature 205 224 1.1E-15 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS10025 d3294514ae33be4d3f9ace6e7a94bc00 1105 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 210 221 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site LK06_RS19825 101b1dd687cc42ff0c76dd85254f5861 197 Pfam PF01386 Ribosomal L25p family 6 91 5.2E-25 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 LK06_RS19825 101b1dd687cc42ff0c76dd85254f5861 197 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 180 26.611 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 LK06_RS19825 101b1dd687cc42ff0c76dd85254f5861 197 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 179 2.1E-20 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain LK06_RS19825 101b1dd687cc42ff0c76dd85254f5861 197 Gene3D G3DSA:2.40.240.10 4 93 5.7E-28 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LK06_RS19825 101b1dd687cc42ff0c76dd85254f5861 197 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 94 8.0E-42 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 LK06_RS19825 101b1dd687cc42ff0c76dd85254f5861 197 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 177 5.1E-42 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 LK06_RS19825 101b1dd687cc42ff0c76dd85254f5861 197 Gene3D G3DSA:2.170.120.20 96 185 2.4E-23 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain LK06_RS19825 101b1dd687cc42ff0c76dd85254f5861 197 SUPERFAMILY SSF50715 4 185 4.88E-50 T 06-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LK06_RS18830 f6aa5baf74115969ee531ba2b190e146 335 SUPERFAMILY SSF46689 273 323 2.97E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS18830 f6aa5baf74115969ee531ba2b190e146 335 SUPERFAMILY SSF52317 6 202 7.72E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS18830 f6aa5baf74115969ee531ba2b190e146 335 Gene3D G3DSA:3.40.50.880 6 202 1.2E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS18830 f6aa5baf74115969ee531ba2b190e146 335 Gene3D G3DSA:1.10.10.60 217 274 2.9E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS18830 f6aa5baf74115969ee531ba2b190e146 335 Gene3D G3DSA:1.10.10.60 275 323 2.1E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS18830 f6aa5baf74115969ee531ba2b190e146 335 SUPERFAMILY SSF46689 224 270 2.04E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS18830 f6aa5baf74115969ee531ba2b190e146 335 Pfam PF01965 DJ-1/PfpI family 7 181 2.5E-15 T 06-07-2017 IPR002818 DJ-1/PfpI LK06_RS18830 f6aa5baf74115969ee531ba2b190e146 335 Pfam PF12833 Helix-turn-helix domain 243 320 1.4E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS18830 f6aa5baf74115969ee531ba2b190e146 335 SMART SM00342 236 319 3.0E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS15465 a7a737b5bf0579fb8deec66183f5536d 504 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 414 492 2.8E-16 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS15465 a7a737b5bf0579fb8deec66183f5536d 504 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 287 1.9E-27 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS15465 a7a737b5bf0579fb8deec66183f5536d 504 SUPERFAMILY SSF51735 8 189 1.97E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15465 a7a737b5bf0579fb8deec66183f5536d 504 SUPERFAMILY SSF48179 413 496 1.36E-15 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS15465 a7a737b5bf0579fb8deec66183f5536d 504 SUPERFAMILY SSF48179 189 297 2.47E-25 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS15465 a7a737b5bf0579fb8deec66183f5536d 504 Gene3D G3DSA:1.10.1040.10 414 493 1.2E-16 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS15465 a7a737b5bf0579fb8deec66183f5536d 504 Gene3D G3DSA:1.10.1040.10 192 287 2.7E-25 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS15465 a7a737b5bf0579fb8deec66183f5536d 504 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 187 1.7E-57 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS15465 a7a737b5bf0579fb8deec66183f5536d 504 Gene3D G3DSA:3.40.50.720 8 191 3.8E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12490 901adbe35e77adcd8c18fbe11ced6cf8 351 Pfam PF01565 FAD binding domain 22 150 1.1E-20 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LK06_RS12490 901adbe35e77adcd8c18fbe11ced6cf8 351 Gene3D G3DSA:3.90.78.10 240 350 4.8E-44 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS12490 901adbe35e77adcd8c18fbe11ced6cf8 351 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 351 77.123 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS12490 901adbe35e77adcd8c18fbe11ced6cf8 351 Gene3D G3DSA:3.30.43.10 8 72 1.9E-23 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS12490 901adbe35e77adcd8c18fbe11ced6cf8 351 SUPERFAMILY SSF56176 8 183 1.5E-37 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS12490 901adbe35e77adcd8c18fbe11ced6cf8 351 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 343 1.8E-47 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS12490 901adbe35e77adcd8c18fbe11ced6cf8 351 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 213 347 3.2E-37 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS12490 901adbe35e77adcd8c18fbe11ced6cf8 351 Gene3D G3DSA:3.30.465.10 223 239 2.0E-47 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS12490 901adbe35e77adcd8c18fbe11ced6cf8 351 Gene3D G3DSA:3.30.465.10 78 188 2.0E-47 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS12490 901adbe35e77adcd8c18fbe11ced6cf8 351 SUPERFAMILY SSF56194 210 349 4.58E-33 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS03380 730e03eee6ea0d3376f4cbcd2abf6942 482 SUPERFAMILY SSF53098 167 306 3.54E-7 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03380 730e03eee6ea0d3376f4cbcd2abf6942 482 Gene3D G3DSA:1.10.10.10 29 53 3.0E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03380 730e03eee6ea0d3376f4cbcd2abf6942 482 Pfam PF00665 Integrase core domain 146 273 1.1E-18 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 LK06_RS03380 730e03eee6ea0d3376f4cbcd2abf6942 482 Gene3D G3DSA:3.30.420.10 175 305 1.6E-7 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 50 275 2.1E-87 T 06-07-2017 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 Gene3D G3DSA:1.10.10.10 213 276 1.1E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 Pfam PF04539 Sigma-70 region 3 130 210 5.0E-7 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 245 271 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 Gene3D G3DSA:1.10.10.10 122 167 5.7E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 Pfam PF04542 Sigma-70 region 2 50 122 4.4E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 275 6.4E-35 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 SUPERFAMILY SSF88659 189 277 1.46E-24 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 PIRSF PIRSF000770 26 278 9.8E-76 T 06-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 SUPERFAMILY SSF88659 123 202 1.79E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 SUPERFAMILY SSF88946 18 122 8.79E-26 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 Gene3D G3DSA:1.10.601.10 30 113 2.7E-16 T 06-07-2017 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 PRINTS PR00046 Major sigma-70 factor signature 77 90 4.3E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 PRINTS PR00046 Major sigma-70 factor signature 228 240 4.3E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 PRINTS PR00046 Major sigma-70 factor signature 260 271 4.3E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 PRINTS PR00046 Major sigma-70 factor signature 245 260 4.3E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24480 50590f988c15f047a0a49c564f86f6e5 280 Pfam PF04545 Sigma-70, region 4 224 273 8.6E-19 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 SUPERFAMILY SSF52954 309 413 4.68E-18 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 Pfam PF03129 Anticodon binding domain 321 408 2.0E-9 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 Gene3D G3DSA:3.30.930.10 7 309 4.7E-90 T 06-07-2017 LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 6 409 1.4E-127 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 Gene3D G3DSA:3.40.50.800 311 414 9.5E-18 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 104 308 3.4E-30 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 SUPERFAMILY SSF55681 7 306 4.74E-81 T 06-07-2017 LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 PRINTS PR01047 Threonyl-tRNA synthetase signature 244 272 3.2E-45 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 PRINTS PR01047 Threonyl-tRNA synthetase signature 314 326 3.2E-45 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 PRINTS PR01047 Threonyl-tRNA synthetase signature 140 163 3.2E-45 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 PRINTS PR01047 Threonyl-tRNA synthetase signature 107 135 3.2E-45 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS15215 79581ef923a4fd10e9fe95f99824528d 420 PRINTS PR01047 Threonyl-tRNA synthetase signature 287 300 3.2E-45 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LK06_RS17565 62d5a834a63281e7242b3d5a566619f5 244 SUPERFAMILY SSF52172 10 196 2.28E-45 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS17565 62d5a834a63281e7242b3d5a566619f5 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 238 2.5E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS17565 62d5a834a63281e7242b3d5a566619f5 244 SMART SM00448 11 122 1.4E-46 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS17565 62d5a834a63281e7242b3d5a566619f5 244 Gene3D G3DSA:1.10.10.10 139 240 6.6E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17565 62d5a834a63281e7242b3d5a566619f5 244 SMART SM00862 163 238 1.5E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS17565 62d5a834a63281e7242b3d5a566619f5 244 Pfam PF00072 Response regulator receiver domain 13 122 1.2E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS17565 62d5a834a63281e7242b3d5a566619f5 244 Gene3D G3DSA:3.40.50.2300 9 131 2.1E-43 T 06-07-2017 LK06_RS06720 d19ebcf16bf7e87b779ad986229e6d7b 184 SUPERFAMILY SSF46767 97 178 2.09E-25 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LK06_RS06720 d19ebcf16bf7e87b779ad986229e6d7b 184 Gene3D G3DSA:1.10.10.10 96 178 2.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06720 d19ebcf16bf7e87b779ad986229e6d7b 184 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 98 178 3.5E-28 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LK06_RS06720 d19ebcf16bf7e87b779ad986229e6d7b 184 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 11 179 37.727 T 06-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 LK06_RS06720 d19ebcf16bf7e87b779ad986229e6d7b 184 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 147 153 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 LK06_RS06720 d19ebcf16bf7e87b779ad986229e6d7b 184 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 11 91 2.5E-5 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 LK06_RS06720 d19ebcf16bf7e87b779ad986229e6d7b 184 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 98 176 1.6E-26 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LK06_RS06720 d19ebcf16bf7e87b779ad986229e6d7b 184 SUPERFAMILY SSF53155 12 92 7.06E-12 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 LK06_RS06720 d19ebcf16bf7e87b779ad986229e6d7b 184 Gene3D G3DSA:3.30.160.70 5 91 1.4E-6 T 06-07-2017 LK06_RS13180 8fab3f95c3a90e94616250b8c9ec0740 179 PRINTS PR01576 Peptide deformylase signature 110 128 7.2E-18 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS13180 8fab3f95c3a90e94616250b8c9ec0740 179 PRINTS PR01576 Peptide deformylase signature 42 71 7.2E-18 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS13180 8fab3f95c3a90e94616250b8c9ec0740 179 PRINTS PR01576 Peptide deformylase signature 98 109 7.2E-18 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS13180 8fab3f95c3a90e94616250b8c9ec0740 179 PRINTS PR01576 Peptide deformylase signature 129 158 7.2E-18 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS13180 8fab3f95c3a90e94616250b8c9ec0740 179 Hamap MF_00163 Peptide deformylase [def]. 2 171 19.912 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS13180 8fab3f95c3a90e94616250b8c9ec0740 179 PIRSF PIRSF004749 1 176 1.4E-29 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS13180 8fab3f95c3a90e94616250b8c9ec0740 179 Pfam PF01327 Polypeptide deformylase 6 157 9.4E-32 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS13180 8fab3f95c3a90e94616250b8c9ec0740 179 Gene3D G3DSA:3.90.45.10 5 159 2.2E-38 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS13180 8fab3f95c3a90e94616250b8c9ec0740 179 SUPERFAMILY SSF56420 4 158 2.62E-35 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS26955 1820e4a0f88f46c458946922338bac21 188 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 12 186 33.607 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 LK06_RS26955 1820e4a0f88f46c458946922338bac21 188 SUPERFAMILY SSF52540 11 185 2.16E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26955 1820e4a0f88f46c458946922338bac21 188 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 2 181 3.0E-58 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 LK06_RS26955 1820e4a0f88f46c458946922338bac21 188 Gene3D G3DSA:3.40.50.300 3 187 5.9E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26955 1820e4a0f88f46c458946922338bac21 188 Pfam PF01583 Adenylylsulphate kinase 14 170 1.6E-57 T 06-07-2017 LK06_RS19205 125484ce23795cb47a716033e8c30b84 262 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 110 130 3.3E-7 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like LK06_RS19205 125484ce23795cb47a716033e8c30b84 262 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 140 154 3.3E-7 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like LK06_RS19205 125484ce23795cb47a716033e8c30b84 262 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 172 186 3.3E-7 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like LK06_RS19205 125484ce23795cb47a716033e8c30b84 262 PIRSF PIRSF003073 10 262 8.9E-75 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein LK06_RS19205 125484ce23795cb47a716033e8c30b84 262 Gene3D G3DSA:3.40.50.300 64 241 1.4E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19205 125484ce23795cb47a716033e8c30b84 262 SUPERFAMILY SSF52540 76 235 1.38E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19205 125484ce23795cb47a716033e8c30b84 262 SMART SM00382 109 242 4.1E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS19205 125484ce23795cb47a716033e8c30b84 262 Pfam PF01695 IstB-like ATP binding protein 65 240 2.9E-52 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 172 735 7.9E-150 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 SUPERFAMILY SSF54665 15 163 3.01E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 Gene3D G3DSA:3.30.365.10 377 478 6.1E-55 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 Gene3D G3DSA:3.30.365.10 651 790 6.1E-55 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 Gene3D G3DSA:3.90.1170.50 14 129 2.3E-42 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 Gene3D G3DSA:3.30.365.10 479 622 1.7E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 Gene3D G3DSA:3.30.365.10 194 298 2.0E-29 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 SUPERFAMILY SSF56003 133 790 3.93E-155 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 Gene3D G3DSA:3.30.365.10 130 193 2.9E-41 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 Gene3D G3DSA:3.30.365.10 301 375 2.9E-41 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 SMART SM01008 34 141 5.9E-49 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS27140 98057cbfffbedb5d2d71b07210c84640 794 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 34 141 4.8E-36 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS10180 fec445c68d2326fbbeed6580f5fbc48f 134 Pfam PF01152 Bacterial-like globin 13 129 6.7E-35 T 06-07-2017 IPR001486 Truncated hemoglobin GO:0019825 LK06_RS10180 fec445c68d2326fbbeed6580f5fbc48f 134 SUPERFAMILY SSF46458 12 133 4.73E-39 T 06-07-2017 IPR009050 Globin-like LK06_RS10180 fec445c68d2326fbbeed6580f5fbc48f 134 Gene3D G3DSA:1.10.490.10 11 133 6.9E-48 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 LK06_RS19065 d4125fb254e401239601c8e559bffc89 282 SMART SM00871 120 282 0.0041 T 06-07-2017 IPR010499 Bacterial transcription activator, effector binding LK06_RS19065 d4125fb254e401239601c8e559bffc89 282 SUPERFAMILY SSF55136 122 282 1.73E-7 T 06-07-2017 IPR011256 Regulatory factor, effector binding domain LK06_RS19065 d4125fb254e401239601c8e559bffc89 282 ProSitePatterns PS00552 MerR-type HTH domain signature. 9 31 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS19065 d4125fb254e401239601c8e559bffc89 282 SMART SM00422 6 76 5.3E-12 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS19065 d4125fb254e401239601c8e559bffc89 282 Gene3D G3DSA:1.10.1660.10 6 107 1.9E-18 T 06-07-2017 LK06_RS19065 d4125fb254e401239601c8e559bffc89 282 SUPERFAMILY SSF46955 5 107 1.76E-19 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS19065 d4125fb254e401239601c8e559bffc89 282 Pfam PF13411 MerR HTH family regulatory protein 7 73 1.0E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS23280 650da930b27e82923bb5dcbc96f683da 79 Gene3D G3DSA:1.20.20.10 15 76 1.1E-19 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 LK06_RS23280 650da930b27e82923bb5dcbc96f683da 79 PRINTS PR00124 ATP synthase C subunit signature 14 33 1.7E-16 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 LK06_RS23280 650da930b27e82923bb5dcbc96f683da 79 PRINTS PR00124 ATP synthase C subunit signature 35 50 1.7E-16 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 LK06_RS23280 650da930b27e82923bb5dcbc96f683da 79 PRINTS PR00124 ATP synthase C subunit signature 52 77 1.7E-16 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 LK06_RS23280 650da930b27e82923bb5dcbc96f683da 79 SUPERFAMILY SSF81333 15 78 3.66E-16 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 LK06_RS23280 650da930b27e82923bb5dcbc96f683da 79 Pfam PF00137 ATP synthase subunit C 17 72 2.0E-10 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 LK06_RS23280 650da930b27e82923bb5dcbc96f683da 79 ProSitePatterns PS00605 ATP synthase c subunit signature. 42 63 - T 06-07-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 LK06_RS23280 650da930b27e82923bb5dcbc96f683da 79 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 22 78 3.7E-13 T 06-07-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 LK06_RS23280 650da930b27e82923bb5dcbc96f683da 79 Hamap MF_01396 ATP synthase subunit c [atpH]. 11 79 14.223 T 06-07-2017 LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 SUPERFAMILY SSF141868 336 591 5.1E-81 T 06-07-2017 IPR001633 EAL domain LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 Gene3D G3DSA:3.30.450.20 24 135 2.0E-18 T 06-07-2017 LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 SUPERFAMILY SSF55073 154 321 3.69E-37 T 06-07-2017 IPR029787 Nucleotide cyclase LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 Pfam PF08448 PAS fold 32 139 2.2E-14 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 145 317 2.9E-29 T 06-07-2017 IPR000160 GGDEF domain LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 SMART SM00267 137 319 8.0E-43 T 06-07-2017 IPR000160 GGDEF domain LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 SMART SM00091 25 91 3.9E-6 T 06-07-2017 IPR000014 PAS domain LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 SUPERFAMILY SSF55785 26 135 2.09E-16 T 06-07-2017 IPR000014 PAS domain LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 Gene3D G3DSA:3.30.70.270 149 324 8.8E-48 T 06-07-2017 LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 25 144 5.4E-17 T 06-07-2017 IPR000014 PAS domain LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 Pfam PF00563 EAL domain 336 581 9.8E-66 T 06-07-2017 IPR001633 EAL domain LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 Gene3D G3DSA:3.20.20.450 333 593 7.9E-106 T 06-07-2017 IPR001633 EAL domain LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 SMART SM00052 329 586 1.7E-100 T 06-07-2017 IPR001633 EAL domain LK06_RS10910 c26852b7541fbdc0f216779ed1568b0c 611 Pfam PF00990 Diguanylate cyclase, GGDEF domain 149 314 4.2E-36 T 06-07-2017 IPR000160 GGDEF domain LK06_RS02995 6086d358793399c92396a6c166268ed6 338 SUPERFAMILY SSF160240 241 321 9.81E-18 T 06-07-2017 LK06_RS02995 6086d358793399c92396a6c166268ed6 338 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 43 320 2.6E-66 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LK06_RS02995 6086d358793399c92396a6c166268ed6 338 SUPERFAMILY SSF161111 41 240 4.58E-45 T 06-07-2017 LK06_RS02995 6086d358793399c92396a6c166268ed6 338 Gene3D G3DSA:3.30.70.1350 240 321 1.4E-19 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain LK06_RS02995 6086d358793399c92396a6c166268ed6 338 Pfam PF16916 Dimerisation domain of Zinc Transporter 243 320 3.0E-16 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain LK06_RS02995 6086d358793399c92396a6c166268ed6 338 Gene3D G3DSA:1.20.1510.10 44 235 1.4E-37 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain LK06_RS02995 6086d358793399c92396a6c166268ed6 338 Pfam PF01545 Cation efflux family 46 237 3.6E-38 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LK06_RS20140 b6f05a2695a7175d2099d3ac23b9eec5 329 Gene3D G3DSA:3.40.190.10 200 287 4.2E-29 T 06-07-2017 LK06_RS20140 b6f05a2695a7175d2099d3ac23b9eec5 329 Gene3D G3DSA:1.10.10.10 3 88 5.1E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20140 b6f05a2695a7175d2099d3ac23b9eec5 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.8E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS20140 b6f05a2695a7175d2099d3ac23b9eec5 329 Pfam PF03466 LysR substrate binding domain 89 314 4.0E-37 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS20140 b6f05a2695a7175d2099d3ac23b9eec5 329 SUPERFAMILY SSF46785 3 112 4.54E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20140 b6f05a2695a7175d2099d3ac23b9eec5 329 SUPERFAMILY SSF53850 91 313 4.03E-32 T 06-07-2017 LK06_RS20140 b6f05a2695a7175d2099d3ac23b9eec5 329 Gene3D G3DSA:3.40.190.10 91 199 2.2E-16 T 06-07-2017 LK06_RS20140 b6f05a2695a7175d2099d3ac23b9eec5 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS20140 b6f05a2695a7175d2099d3ac23b9eec5 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS20140 b6f05a2695a7175d2099d3ac23b9eec5 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS03530 210a886e5068f95c119c6c545aa36ca2 342 Pfam PF01636 Phosphotransferase enzyme family 24 219 6.7E-13 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS03530 210a886e5068f95c119c6c545aa36ca2 342 SUPERFAMILY SSF56112 22 248 1.86E-28 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS03530 210a886e5068f95c119c6c545aa36ca2 342 Gene3D G3DSA:3.90.1200.10 96 226 5.4E-10 T 06-07-2017 LK06_RS26835 75dd2d2ba64c6b58fa5ada603f999af7 375 Pfam PF01321 Creatinase/Prolidase N-terminal domain 17 149 8.0E-14 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 LK06_RS26835 75dd2d2ba64c6b58fa5ada603f999af7 375 Gene3D G3DSA:3.90.230.10 149 373 1.0E-67 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS26835 75dd2d2ba64c6b58fa5ada603f999af7 375 Gene3D G3DSA:3.40.350.10 6 144 1.0E-13 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal LK06_RS26835 75dd2d2ba64c6b58fa5ada603f999af7 375 Pfam PF00557 Metallopeptidase family M24 158 358 6.3E-55 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS26835 75dd2d2ba64c6b58fa5ada603f999af7 375 SUPERFAMILY SSF53092 6 147 9.94E-19 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal LK06_RS26835 75dd2d2ba64c6b58fa5ada603f999af7 375 SUPERFAMILY SSF55920 148 374 1.31E-70 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS10600 8972564f7db67f174453a57ebec87fdc 79 SUPERFAMILY SSF55008 8 75 6.28E-15 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 LK06_RS10600 8972564f7db67f174453a57ebec87fdc 79 Gene3D G3DSA:3.30.70.100 12 75 2.4E-18 T 06-07-2017 LK06_RS10600 8972564f7db67f174453a57ebec87fdc 79 Pfam PF00403 Heavy-metal-associated domain 15 74 7.4E-12 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 LK06_RS10600 8972564f7db67f174453a57ebec87fdc 79 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 47 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 24 674 2.0E-195 T 06-07-2017 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 SUPERFAMILY SSF54862 98 233 4.6E-31 T 06-07-2017 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 242 289 1.3E-5 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 168 178 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Gene3D G3DSA:3.10.20.30 22 76 6.0E-7 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Gene3D G3DSA:2.20.25.90 242 290 1.2E-10 T 06-07-2017 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 SMART SM00929 105 145 4.2E-19 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Gene3D G3DSA:3.40.50.740 404 441 7.4E-43 T 06-07-2017 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Gene3D G3DSA:3.40.50.740 295 363 7.4E-43 T 06-07-2017 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Gene3D G3DSA:3.40.50.740 560 698 7.4E-43 T 06-07-2017 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 120 132 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 144 5.5E-16 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 20 95 9.8E-20 T 06-07-2017 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 51 68 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Pfam PF00384 Molybdopterin oxidoreductase 525 658 4.8E-8 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Pfam PF00384 Molybdopterin oxidoreductase 295 440 1.6E-11 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Gene3D G3DSA:2.40.40.20 748 813 6.5E-4 T 06-07-2017 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 SUPERFAMILY SSF53706 229 705 8.86E-80 T 06-07-2017 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 SUPERFAMILY SSF54292 22 94 1.71E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 SUPERFAMILY SSF50692 732 801 3.62E-5 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 SMART SM00926 238 292 2.7E-7 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12925 c53cc130b237d11cecb3f2deac0f3548 834 Gene3D G3DSA:3.30.70.20 159 225 8.1E-4 T 06-07-2017 LK06_RS01755 814354f95e689da146535a21a37d3939 775 Gene3D G3DSA:3.30.2080.10 621 768 4.1E-41 T 06-07-2017 LK06_RS01755 814354f95e689da146535a21a37d3939 775 Gene3D G3DSA:1.20.1050.60 352 441 5.3E-24 T 06-07-2017 LK06_RS01755 814354f95e689da146535a21a37d3939 775 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 25 761 3.2E-163 T 06-07-2017 IPR005887 Alpha-1,2-mannosidase, putative LK06_RS01755 814354f95e689da146535a21a37d3939 775 Gene3D G3DSA:2.70.98.10 38 328 3.2E-96 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 LK06_RS01755 814354f95e689da146535a21a37d3939 775 Gene3D G3DSA:1.20.1610.10 452 620 5.3E-48 T 06-07-2017 LK06_RS01755 814354f95e689da146535a21a37d3939 775 Pfam PF07971 Glycosyl hydrolase family 92 245 757 8.9E-135 T 06-07-2017 IPR012939 Glycosyl hydrolase family 92 LK06_RS01755 814354f95e689da146535a21a37d3939 775 SUPERFAMILY SSF48208 275 740 1.79E-27 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS15015 4471a6dedeb68db797ca81b0a1ecded5 508 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 269 421 2.0E-22 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15015 4471a6dedeb68db797ca81b0a1ecded5 508 SUPERFAMILY SSF143243 4 170 1.44E-26 T 06-07-2017 LK06_RS15015 4471a6dedeb68db797ca81b0a1ecded5 508 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 78 99 - T 06-07-2017 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15015 4471a6dedeb68db797ca81b0a1ecded5 508 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 34 116 2.1E-13 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15015 4471a6dedeb68db797ca81b0a1ecded5 508 Gene3D G3DSA:1.10.645.10 145 499 2.3E-51 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15015 4471a6dedeb68db797ca81b0a1ecded5 508 SUPERFAMILY SSF56762 166 507 2.88E-81 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15015 4471a6dedeb68db797ca81b0a1ecded5 508 Pfam PF00374 Nickel-dependent hydrogenase 195 261 1.1E-6 T 06-07-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 LK06_RS15015 4471a6dedeb68db797ca81b0a1ecded5 508 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 62 112 4.0E-16 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS04995 27184ccf5dea1bfee481ffb521c6505e 453 PIRSF PIRSF018077 1 453 9.4E-181 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 LK06_RS04995 27184ccf5dea1bfee481ffb521c6505e 453 Pfam PF03136 Pup-ligase protein 4 423 4.0E-156 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 LK06_RS04995 27184ccf5dea1bfee481ffb521c6505e 453 Hamap MF_02111 Pup--protein ligase [pafA]. 1 453 49.828 T 06-07-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 LK06_RS04995 27184ccf5dea1bfee481ffb521c6505e 453 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 453 2.1E-230 T 06-07-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 LK06_RS29390 9a2e7106fda42a3e619b8e69e2556d9c 256 Pfam PF11209 Protein of unknown function (DUF2993) 43 241 2.3E-12 T 06-07-2017 IPR021373 Protein of unknown function DUF2993 LK06_RS29340 4571c75f7fa802ff4c87ee1a4d28b215 301 PRINTS PR01438 Universal stress protein signature 2 20 4.1E-13 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS29340 4571c75f7fa802ff4c87ee1a4d28b215 301 PRINTS PR01438 Universal stress protein signature 98 110 4.1E-13 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS29340 4571c75f7fa802ff4c87ee1a4d28b215 301 PRINTS PR01438 Universal stress protein signature 116 138 4.1E-13 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS29340 4571c75f7fa802ff4c87ee1a4d28b215 301 Gene3D G3DSA:3.40.50.620 1 138 8.5E-35 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS29340 4571c75f7fa802ff4c87ee1a4d28b215 301 Gene3D G3DSA:3.40.50.620 157 298 9.0E-24 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS29340 4571c75f7fa802ff4c87ee1a4d28b215 301 Pfam PF00582 Universal stress protein family 161 298 2.6E-19 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS29340 4571c75f7fa802ff4c87ee1a4d28b215 301 Pfam PF00582 Universal stress protein family 1 138 5.0E-27 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS29340 4571c75f7fa802ff4c87ee1a4d28b215 301 SUPERFAMILY SSF52402 161 298 2.09E-19 T 06-07-2017 LK06_RS29340 4571c75f7fa802ff4c87ee1a4d28b215 301 SUPERFAMILY SSF52402 3 139 3.18E-31 T 06-07-2017 LK06_RS06945 dca8296dfd8a49e77802806ff5a2a7b1 452 Gene3D G3DSA:3.40.640.10 93 344 7.9E-70 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS06945 dca8296dfd8a49e77802806ff5a2a7b1 452 Gene3D G3DSA:3.90.1150.10 345 447 5.3E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS06945 dca8296dfd8a49e77802806ff5a2a7b1 452 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 77 390 9.8E-36 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 LK06_RS06945 dca8296dfd8a49e77802806ff5a2a7b1 452 SUPERFAMILY SSF53383 37 446 9.46E-90 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS25480 c1e4848c67400d0e86d2268405dfcec6 186 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 9 151 30.962 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 LK06_RS25480 c1e4848c67400d0e86d2268405dfcec6 186 Pfam PF00692 dUTPase 21 150 3.4E-28 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 LK06_RS25480 c1e4848c67400d0e86d2268405dfcec6 186 Gene3D G3DSA:2.70.40.10 8 150 4.2E-51 T 06-07-2017 IPR029054 dUTPase-like LK06_RS25480 c1e4848c67400d0e86d2268405dfcec6 186 SUPERFAMILY SSF51283 10 150 6.28E-43 T 06-07-2017 IPR029054 dUTPase-like LK06_RS25480 c1e4848c67400d0e86d2268405dfcec6 186 TIGRFAM TIGR00576 dut: dUTP diphosphatase 13 150 5.7E-49 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 LK06_RS12505 d1d9b756c6c873a23499913d467b762a 142 PRINTS PR01483 Fatty acid synthase signature 25 47 2.3E-7 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 LK06_RS12505 d1d9b756c6c873a23499913d467b762a 142 PRINTS PR01483 Fatty acid synthase signature 47 68 2.3E-7 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 LK06_RS12505 d1d9b756c6c873a23499913d467b762a 142 Gene3D G3DSA:3.10.129.10 8 141 2.4E-40 T 06-07-2017 IPR029069 HotDog domain LK06_RS12505 d1d9b756c6c873a23499913d467b762a 142 SUPERFAMILY SSF54637 4 139 3.52E-31 T 06-07-2017 IPR029069 HotDog domain LK06_RS12505 d1d9b756c6c873a23499913d467b762a 142 Pfam PF01575 MaoC like domain 14 124 4.2E-26 T 06-07-2017 IPR002539 MaoC-like domain LK06_RS09165 e105d2d28bcb899cfd3b031193a0e9cb 642 Pfam PF00005 ABC transporter 414 563 2.2E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS09165 e105d2d28bcb899cfd3b031193a0e9cb 642 Gene3D G3DSA:3.40.50.300 397 627 3.5E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09165 e105d2d28bcb899cfd3b031193a0e9cb 642 SMART SM00382 422 609 1.0E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS09165 e105d2d28bcb899cfd3b031193a0e9cb 642 SUPERFAMILY SSF52540 391 634 3.52E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09165 e105d2d28bcb899cfd3b031193a0e9cb 642 SUPERFAMILY SSF90123 26 70 3.01E-84 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS09165 e105d2d28bcb899cfd3b031193a0e9cb 642 SUPERFAMILY SSF90123 111 386 3.01E-84 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS09165 e105d2d28bcb899cfd3b031193a0e9cb 642 Gene3D G3DSA:1.20.1560.10 108 381 3.0E-86 T 06-07-2017 LK06_RS09165 e105d2d28bcb899cfd3b031193a0e9cb 642 Gene3D G3DSA:1.20.1560.10 26 70 3.0E-86 T 06-07-2017 LK06_RS09165 e105d2d28bcb899cfd3b031193a0e9cb 642 ProSitePatterns PS00211 ABC transporters family signature. 535 549 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS09165 e105d2d28bcb899cfd3b031193a0e9cb 642 Pfam PF00664 ABC transporter transmembrane region 43 351 3.0E-55 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS03300 6d33aaf8b494b07d19e2ab30fdecc479 168 Pfam PF00355 Rieske [2Fe-2S] domain 77 155 8.2E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS03300 6d33aaf8b494b07d19e2ab30fdecc479 168 SUPERFAMILY SSF50022 75 167 1.7E-26 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS03300 6d33aaf8b494b07d19e2ab30fdecc479 168 Gene3D G3DSA:2.102.10.10 12 167 8.9E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS03300 6d33aaf8b494b07d19e2ab30fdecc479 168 PRINTS PR00162 Rieske 2Fe-2S subunit signature 128 140 1.3E-7 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 LK06_RS03300 6d33aaf8b494b07d19e2ab30fdecc479 168 PRINTS PR00162 Rieske 2Fe-2S subunit signature 141 153 1.3E-7 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 LK06_RS03300 6d33aaf8b494b07d19e2ab30fdecc479 168 PRINTS PR00162 Rieske 2Fe-2S subunit signature 108 119 1.3E-7 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 LK06_RS02195 a276fa1987aff3592cf1c0f5347fefbf 461 Gene3D G3DSA:3.40.605.10 3 247 1.0E-71 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS02195 a276fa1987aff3592cf1c0f5347fefbf 461 SUPERFAMILY SSF53720 3 460 1.26E-144 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS02195 a276fa1987aff3592cf1c0f5347fefbf 461 Gene3D G3DSA:3.40.309.10 248 432 2.3E-67 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS02195 a276fa1987aff3592cf1c0f5347fefbf 461 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 261 272 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 LK06_RS02195 a276fa1987aff3592cf1c0f5347fefbf 461 Pfam PF00171 Aldehyde dehydrogenase family 3 457 1.5E-141 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS17015 53fc9f5dee96e9122bd407d03f2f0eda 90 SUPERFAMILY SSF82697 3 81 2.09E-25 T 06-07-2017 LK06_RS17015 53fc9f5dee96e9122bd407d03f2f0eda 90 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 78 1.6E-27 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS17015 53fc9f5dee96e9122bd407d03f2f0eda 90 Gene3D G3DSA:3.30.1280.10 3 81 2.8E-32 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS17015 53fc9f5dee96e9122bd407d03f2f0eda 90 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 21.804 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS17015 53fc9f5dee96e9122bd407d03f2f0eda 90 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 3.0E-33 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS17015 53fc9f5dee96e9122bd407d03f2f0eda 90 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 81 1.1E-20 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS02985 50afd9cd74ad62d6c4a3cd6a46ec09b1 545 PIRSF PIRSF006060 4 471 4.4E-75 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS02985 50afd9cd74ad62d6c4a3cd6a46ec09b1 545 Pfam PF13520 Amino acid permease 23 425 1.0E-45 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS25860 f4d0127acdf65c6237de53dcb46d5f11 341 Gene3D G3DSA:3.90.25.10 203 307 1.0E-11 T 06-07-2017 LK06_RS25860 f4d0127acdf65c6237de53dcb46d5f11 341 SUPERFAMILY SSF51735 2 312 9.78E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25860 f4d0127acdf65c6237de53dcb46d5f11 341 Gene3D G3DSA:3.40.50.720 2 202 6.6E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25860 f4d0127acdf65c6237de53dcb46d5f11 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 236 5.5E-40 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS24430 41bdafbf0da5c4a0b1fc3fcd882736ce 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 28.749 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24430 41bdafbf0da5c4a0b1fc3fcd882736ce 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 1.3E-47 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24430 41bdafbf0da5c4a0b1fc3fcd882736ce 116 Pfam PF01245 Ribosomal protein L19 4 113 1.2E-48 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24430 41bdafbf0da5c4a0b1fc3fcd882736ce 116 PRINTS PR00061 Ribosomal protein L19 signature 88 113 3.3E-42 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24430 41bdafbf0da5c4a0b1fc3fcd882736ce 116 PRINTS PR00061 Ribosomal protein L19 signature 34 63 3.3E-42 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24430 41bdafbf0da5c4a0b1fc3fcd882736ce 116 PRINTS PR00061 Ribosomal protein L19 signature 4 33 3.3E-42 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24430 41bdafbf0da5c4a0b1fc3fcd882736ce 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 06-07-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24430 41bdafbf0da5c4a0b1fc3fcd882736ce 116 SUPERFAMILY SSF50104 4 115 2.51E-44 T 06-07-2017 IPR008991 Translation protein SH3-like domain LK06_RS24430 41bdafbf0da5c4a0b1fc3fcd882736ce 116 PIRSF PIRSF002191 1 116 2.1E-48 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS14670 5f72d021d3f634ecb6e2b01361f2bcb8 803 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 737 751 8.8E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14670 5f72d021d3f634ecb6e2b01361f2bcb8 803 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 751 767 8.8E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14670 5f72d021d3f634ecb6e2b01361f2bcb8 803 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 767 779 8.8E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14670 5f72d021d3f634ecb6e2b01361f2bcb8 803 SMART SM00382 78 267 0.0092 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS14670 5f72d021d3f634ecb6e2b01361f2bcb8 803 Pfam PF00196 Bacterial regulatory proteins, luxR family 736 791 5.7E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14670 5f72d021d3f634ecb6e2b01361f2bcb8 803 Gene3D G3DSA:3.40.50.300 59 181 1.7E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14670 5f72d021d3f634ecb6e2b01361f2bcb8 803 SUPERFAMILY SSF46894 731 794 2.89E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS14670 5f72d021d3f634ecb6e2b01361f2bcb8 803 Gene3D G3DSA:1.10.10.10 724 794 3.0E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14670 5f72d021d3f634ecb6e2b01361f2bcb8 803 SMART SM00421 734 791 1.7E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14670 5f72d021d3f634ecb6e2b01361f2bcb8 803 SUPERFAMILY SSF52540 56 314 9.87E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12305 e7643345b6f90f1e3fad4c7087f4c5d5 139 Gene3D G3DSA:3.30.70.330 45 135 9.8E-37 T 06-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 LK06_RS12305 e7643345b6f90f1e3fad4c7087f4c5d5 139 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 47 136 22.782 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 LK06_RS12305 e7643345b6f90f1e3fad4c7087f4c5d5 139 ProSitePatterns PS00050 Ribosomal protein L23 signature. 119 134 - T 06-07-2017 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12305 e7643345b6f90f1e3fad4c7087f4c5d5 139 Pfam PF00276 Ribosomal protein L23 48 133 2.2E-32 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 LK06_RS12305 e7643345b6f90f1e3fad4c7087f4c5d5 139 SUPERFAMILY SSF54189 44 136 1.26E-32 T 06-07-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS20260 506153b3f2701bc65382476ecb2b6d4b 430 Pfam PF04024 PspC domain 16 71 8.6E-15 T 06-07-2017 IPR007168 Phage shock protein, PspC, N-terminal LK06_RS20260 506153b3f2701bc65382476ecb2b6d4b 430 Pfam PF13581 Histidine kinase-like ATPase domain 297 388 1.7E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20260 506153b3f2701bc65382476ecb2b6d4b 430 Gene3D G3DSA:3.30.565.10 314 426 2.4E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20260 506153b3f2701bc65382476ecb2b6d4b 430 SUPERFAMILY SSF55874 312 422 6.16E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04705 76ee38d4279b1b1663c251791741c360 383 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 383 132.122 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LK06_RS04705 76ee38d4279b1b1663c251791741c360 383 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 20 381 0.0 T 06-07-2017 LK06_RS04705 76ee38d4279b1b1663c251791741c360 383 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 382 2.3E-103 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LK06_RS04705 76ee38d4279b1b1663c251791741c360 383 Gene3D G3DSA:3.60.70.12 2 259 2.4E-93 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LK06_RS04705 76ee38d4279b1b1663c251791741c360 383 Pfam PF01960 ArgJ family 11 383 4.1E-128 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LK06_RS04705 76ee38d4279b1b1663c251791741c360 383 SUPERFAMILY SSF56266 7 379 1.18E-127 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LK06_RS16195 df215edc2aa4730bb436ab190515e748 280 Pfam PF00557 Metallopeptidase family M24 15 255 1.4E-28 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS16195 df215edc2aa4730bb436ab190515e748 280 SUPERFAMILY SSF55920 11 256 3.14E-26 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS16195 df215edc2aa4730bb436ab190515e748 280 Gene3D G3DSA:3.90.230.10 11 256 8.8E-28 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS16015 a24e966704859cf05c1c3905c5c99fcc 492 Gene3D G3DSA:1.10.860.10 57 159 1.2E-41 T 06-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal LK06_RS16015 a24e966704859cf05c1c3905c5c99fcc 492 SUPERFAMILY SSF52540 230 481 1.78E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16015 a24e966704859cf05c1c3905c5c99fcc 492 SMART SM00382 249 448 0.001 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS16015 a24e966704859cf05c1c3905c5c99fcc 492 Pfam PF03796 DnaB-like helicase C terminal domain 232 487 1.1E-108 T 06-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 LK06_RS16015 a24e966704859cf05c1c3905c5c99fcc 492 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 57 490 1.0E-167 T 06-07-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 LK06_RS16015 a24e966704859cf05c1c3905c5c99fcc 492 Gene3D G3DSA:3.40.50.300 217 491 4.4E-119 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16015 a24e966704859cf05c1c3905c5c99fcc 492 SUPERFAMILY SSF48024 55 166 9.29E-39 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 LK06_RS16015 a24e966704859cf05c1c3905c5c99fcc 492 Pfam PF00772 DnaB-like helicase N terminal domain 57 158 3.7E-37 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 LK06_RS02510 b72550f61158ab40392ba4f0c0c2e95d 217 SUPERFAMILY SSF48498 87 194 2.17E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS02510 b72550f61158ab40392ba4f0c0c2e95d 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 8.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS02510 b72550f61158ab40392ba4f0c0c2e95d 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 8.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS02510 b72550f61158ab40392ba4f0c0c2e95d 217 Gene3D G3DSA:1.10.357.10 16 194 3.6E-42 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS02510 b72550f61158ab40392ba4f0c0c2e95d 217 Pfam PF13305 WHG domain 90 175 7.5E-14 T 06-07-2017 IPR025996 WHG domain LK06_RS02510 b72550f61158ab40392ba4f0c0c2e95d 217 SUPERFAMILY SSF46689 15 77 4.36E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02510 b72550f61158ab40392ba4f0c0c2e95d 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 9.7E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30420 d21ffdc001a85a90b72e097c905e70b4 146 Gene3D G3DSA:1.10.10.10 5 138 7.7E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30420 d21ffdc001a85a90b72e097c905e70b4 146 SMART SM00347 26 126 3.2E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS30420 d21ffdc001a85a90b72e097c905e70b4 146 Pfam PF01047 MarR family 33 89 6.1E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS30420 d21ffdc001a85a90b72e097c905e70b4 146 SUPERFAMILY SSF46785 13 138 4.06E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27480 30d1beeba828fd5b08f7765ec095f3a4 416 SMART SM00530 19 75 1.2E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS27480 30d1beeba828fd5b08f7765ec095f3a4 416 Gene3D G3DSA:1.10.260.40 16 84 1.1E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS27480 30d1beeba828fd5b08f7765ec095f3a4 416 Pfam PF13560 Helix-turn-helix domain 15 72 1.6E-15 T 06-07-2017 LK06_RS27480 30d1beeba828fd5b08f7765ec095f3a4 416 SUPERFAMILY SSF47413 11 74 8.45E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS21885 fc6833ae013895a5c7d17a0ff32f0f96 542 Gene3D G3DSA:3.10.105.10 322 513 1.9E-39 T 06-07-2017 LK06_RS21885 fc6833ae013895a5c7d17a0ff32f0f96 542 Gene3D G3DSA:3.40.190.10 206 321 4.9E-27 T 06-07-2017 LK06_RS21885 fc6833ae013895a5c7d17a0ff32f0f96 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 462 7.1E-51 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS21885 fc6833ae013895a5c7d17a0ff32f0f96 542 Gene3D G3DSA:3.90.76.10 49 205 1.4E-33 T 06-07-2017 LK06_RS21885 fc6833ae013895a5c7d17a0ff32f0f96 542 SUPERFAMILY SSF53850 37 541 9.1E-94 T 06-07-2017 LK06_RS21885 fc6833ae013895a5c7d17a0ff32f0f96 542 PIRSF PIRSF002741 9 541 3.2E-68 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LK06_RS24135 5ec5f6677cc835da39d2c4ef90bf6f47 243 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 85 201 2.0E-8 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS24135 5ec5f6677cc835da39d2c4ef90bf6f47 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 2.8E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS24135 5ec5f6677cc835da39d2c4ef90bf6f47 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 2.8E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS24135 5ec5f6677cc835da39d2c4ef90bf6f47 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 2.8E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS24135 5ec5f6677cc835da39d2c4ef90bf6f47 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 2.8E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS24135 5ec5f6677cc835da39d2c4ef90bf6f47 243 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 202 3.1E-18 T 06-07-2017 IPR023214 HAD-like domain LK06_RS24135 5ec5f6677cc835da39d2c4ef90bf6f47 243 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 196 9.4E-12 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS24135 5ec5f6677cc835da39d2c4ef90bf6f47 243 SUPERFAMILY SSF56784 2 231 2.51E-46 T 06-07-2017 IPR023214 HAD-like domain LK06_RS24135 5ec5f6677cc835da39d2c4ef90bf6f47 243 Gene3D G3DSA:3.40.50.1000 1 227 3.6E-41 T 06-07-2017 IPR023214 HAD-like domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00668 Condensation domain 3810 4102 6.0E-64 T 06-07-2017 IPR001242 Condensation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00668 Condensation domain 2087 2385 1.6E-63 T 06-07-2017 IPR001242 Condensation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00668 Condensation domain 418 701 9.3E-59 T 06-07-2017 IPR001242 Condensation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00668 Condensation domain 5762 6060 2.6E-59 T 06-07-2017 IPR001242 Condensation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00668 Condensation domain 4727 5025 3.0E-60 T 06-07-2017 IPR001242 Condensation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00668 Condensation domain 1095 1371 1.8E-32 T 06-07-2017 IPR001242 Condensation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00668 Condensation domain 6811 7085 3.6E-32 T 06-07-2017 IPR001242 Condensation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00668 Condensation domain 1538 1827 2.4E-57 T 06-07-2017 IPR001242 Condensation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00668 Condensation domain 3143 3443 8.7E-62 T 06-07-2017 IPR001242 Condensation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 3332 3584 3.0E-59 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 591 841 9.0E-58 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13193 AMP-binding enzyme C-terminal domain 6624 6695 8.8E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13193 AMP-binding enzyme C-terminal domain 4548 4616 3.1E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13193 AMP-binding enzyme C-terminal domain 240 311 1.4E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13193 AMP-binding enzyme C-terminal domain 2965 3035 9.1E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13193 AMP-binding enzyme C-terminal domain 910 972 1.9E-5 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13193 AMP-binding enzyme C-terminal domain 5581 5652 1.8E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5702 5717 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4667 4682 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 1090 1245 4.0E-27 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF56801 4264 4656 2.22E-56 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 421 597 1.67E-45 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 4729 4901 1.22E-48 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 2092 2261 2.22E-45 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00501 AMP-binding enzyme 4325 4533 4.4E-22 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00501 AMP-binding enzyme 6228 6616 7.6E-98 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00501 AMP-binding enzyme 7 232 1.9E-47 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00501 AMP-binding enzyme 5197 5573 4.5E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00501 AMP-binding enzyme 2556 2957 8.6E-98 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1378 1529 2.0E-28 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 7092 7239 7.1E-34 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 ProSitePatterns PS00455 Putative AMP-binding domain signature. 6368 6379 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF47336 3720 3791 1.01E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6745 6760 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.40.50.980 2703 2857 1.9E-47 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 6968 7215 2.22E-30 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF47336 3054 3123 4.45E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3084 3099 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 ProSitePatterns PS00012 Phosphopantetheine attachment site. 359 374 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13745 HxxPF-repeated domain 3465 3560 6.4E-27 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13745 HxxPF-repeated domain 5047 5142 4.1E-29 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13745 HxxPF-repeated domain 2407 2502 2.6E-30 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13745 HxxPF-repeated domain 4124 4221 4.0E-28 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13745 HxxPF-repeated domain 724 818 2.4E-28 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF13745 HxxPF-repeated domain 6082 6171 5.3E-31 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 1536 1729 1.07E-41 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:1.10.1200.10 999 1061 3.3E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:1.10.1200.10 4648 4708 4.7E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:1.10.1200.10 1996 2075 2.0E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:1.10.1200.10 6711 6786 6.6E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:1.10.1200.10 3065 3129 2.3E-27 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:1.10.1200.10 339 403 1.9E-27 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:1.10.1200.10 3732 3797 1.6E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:1.10.1200.10 5668 5743 9.1E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2029 2044 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 6249 6639 1.8E-133 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2577 2981 2.8E-135 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5218 5595 2.3E-125 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 3991 4242 4.34E-59 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF56801 2515 3073 2.49E-159 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:2.30.38.10 4464 4532 1.7E-9 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:2.30.38.10 5486 5563 5.6E-29 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:2.30.38.10 6529 6605 1.9E-27 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:2.30.38.10 2868 2946 3.2E-22 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:2.30.38.10 145 221 1.5E-27 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF56801 858 1008 8.63E-14 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF56801 2 348 5.1E-92 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1019 1034 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.30.300.30 6610 6709 3.5E-34 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.30.300.30 5567 5666 4.6E-34 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF47336 6715 6783 3.8E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 1714 1952 1.89E-50 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 1250 1505 3.45E-26 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.40.50.980 1 144 9.5E-35 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.40.50.980 5346 5485 1.0E-35 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.40.50.980 6390 6528 3.6E-40 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.40.50.980 4324 4463 1.1E-14 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.30.300.30 227 338 1.3E-34 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.30.300.30 4538 4647 3.1E-20 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.30.300.30 910 998 4.9E-13 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.30.300.30 3637 3731 4.7E-7 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.30.300.30 2952 3064 3.9E-38 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00550 Phosphopantetheine attachment site 4646 4705 2.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00550 Phosphopantetheine attachment site 337 400 8.1E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00550 Phosphopantetheine attachment site 2008 2069 3.7E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00550 Phosphopantetheine attachment site 997 1058 2.8E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00550 Phosphopantetheine attachment site 3729 3791 3.4E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00550 Phosphopantetheine attachment site 6723 6783 6.5E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00550 Phosphopantetheine attachment site 3063 3124 1.4E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Pfam PF00550 Phosphopantetheine attachment site 5680 5740 2.3E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2694 2705 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF47336 328 401 2.36E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 2274 2520 5.45E-64 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF47336 993 1057 1.11E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF56801 6221 6734 1.57E-155 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 6798 6961 8.23E-29 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF47336 1998 2070 5.23E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SMART SM00823 Phosphopantetheine attachment site 6721 6789 8.6E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SMART SM00823 Phosphopantetheine attachment site 5678 5747 1.3E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SMART SM00823 Phosphopantetheine attachment site 4643 4712 4.2E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SMART SM00823 Phosphopantetheine attachment site 995 1063 1.3E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SMART SM00823 Phosphopantetheine attachment site 3726 3795 4.6E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SMART SM00823 Phosphopantetheine attachment site 3060 3129 1.0E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SMART SM00823 Phosphopantetheine attachment site 335 404 3.7E-10 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SMART SM00823 Phosphopantetheine attachment site 2005 2074 1.3E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF56801 5161 5691 2.22E-146 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3750 3765 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 3812 3978 1.33E-48 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF56801 3597 3739 1.26E-15 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 3146 3319 2.0E-49 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF47336 5672 5743 5.1E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.40.50.980 6223 6389 4.0E-48 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.40.50.980 5192 5345 3.8E-46 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 Gene3D G3DSA:3.40.50.980 2549 2702 1.0E-50 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 5950 6189 2.22E-63 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 4915 5184 2.33E-62 T 06-07-2017 LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF47336 4637 4708 5.5E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21035 7d716b04ce011dc661e1722552b60682 7246 SUPERFAMILY SSF52777 5764 5936 1.22E-48 T 06-07-2017 LK06_RS12910 2dba070b390be43cc194aff7a9902f1d 281 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 29 174 5.3E-32 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 Pfam PF00067 Cytochrome P450 269 403 1.5E-17 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 PRINTS PR00359 B-class P450 signature 325 352 1.6E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 PRINTS PR00359 B-class P450 signature 223 245 1.6E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 PRINTS PR00359 B-class P450 signature 353 368 1.6E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 PRINTS PR00359 B-class P450 signature 374 383 1.6E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 PRINTS PR00359 B-class P450 signature 383 394 1.6E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 PRINTS PR00359 B-class P450 signature 308 319 1.6E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 PRINTS PR00359 B-class P450 signature 181 196 1.6E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 PRINTS PR00359 B-class P450 signature 118 129 1.6E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 SUPERFAMILY SSF48264 39 433 1.83E-79 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 376 385 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS29405 61ee09fa05a489f1f037baf69662959e 434 Gene3D G3DSA:1.10.630.10 10 433 4.5E-101 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS06585 d96af205e92f091ccc4bb221850e0456 168 SUPERFAMILY SSF46785 2 167 1.36E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06585 d96af205e92f091ccc4bb221850e0456 168 Pfam PF10400 Virulence activator alpha C-term 91 168 7.6E-10 T 06-07-2017 IPR018309 Transcription regulator PadR, C-terminal LK06_RS06585 d96af205e92f091ccc4bb221850e0456 168 Pfam PF03551 Transcriptional regulator PadR-like family 5 79 1.1E-20 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal LK06_RS06585 d96af205e92f091ccc4bb221850e0456 168 Gene3D G3DSA:1.10.10.10 2 86 3.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27000 837a664ecd8d768933f92bbb2cd67606 229 Pfam PF12833 Helix-turn-helix domain 150 225 1.6E-14 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS27000 837a664ecd8d768933f92bbb2cd67606 229 SMART SM00342 143 225 6.3E-10 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS25980 a9ba1daa159456d8be46db0431e85a3d 434 PIRSF PIRSF006060 1 424 2.2E-48 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS25980 a9ba1daa159456d8be46db0431e85a3d 434 Pfam PF13520 Amino acid permease 10 402 2.9E-34 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS29955 b17b20a15fb06c184e876187265907df 321 Gene3D G3DSA:3.40.50.1220 191 317 1.0E-58 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS29955 b17b20a15fb06c184e876187265907df 321 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 197 279 8.7E-36 T 06-07-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 LK06_RS29955 b17b20a15fb06c184e876187265907df 321 Pfam PF01012 Electron transfer flavoprotein domain 4 169 6.7E-26 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 LK06_RS29955 b17b20a15fb06c184e876187265907df 321 PIRSF PIRSF000089 1 321 7.7E-96 T 06-07-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 LK06_RS29955 b17b20a15fb06c184e876187265907df 321 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 260 286 - T 06-07-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 LK06_RS29955 b17b20a15fb06c184e876187265907df 321 SMART SM00893 4 184 6.0E-19 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 LK06_RS29955 b17b20a15fb06c184e876187265907df 321 Gene3D G3DSA:3.40.50.620 3 184 1.8E-34 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS29955 b17b20a15fb06c184e876187265907df 321 SUPERFAMILY SSF52402 3 187 6.14E-33 T 06-07-2017 LK06_RS29955 b17b20a15fb06c184e876187265907df 321 SUPERFAMILY SSF52467 195 316 5.54E-47 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS10365 8e90505aeed3a2fea7dd460af02e741d 387 SUPERFAMILY SSF53756 4 365 1.19E-62 T 06-07-2017 LK06_RS10365 8e90505aeed3a2fea7dd460af02e741d 387 Pfam PF00534 Glycosyl transferases group 1 183 310 1.0E-15 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS10365 8e90505aeed3a2fea7dd460af02e741d 387 Pfam PF13439 Glycosyltransferase Family 4 12 169 1.0E-24 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS10365 8e90505aeed3a2fea7dd460af02e741d 387 Gene3D G3DSA:3.40.50.2000 151 307 4.4E-22 T 06-07-2017 LK06_RS01810 fee8578b02e6e26a92d173ddfc96e04b 449 SUPERFAMILY SSF52540 241 296 2.67E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01810 fee8578b02e6e26a92d173ddfc96e04b 449 SUPERFAMILY SSF52540 45 102 2.67E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01810 fee8578b02e6e26a92d173ddfc96e04b 449 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 12 417 7.1E-136 T 06-07-2017 IPR021228 Protein of unknown function DUF2791 LK06_RS01810 fee8578b02e6e26a92d173ddfc96e04b 449 Gene3D G3DSA:3.40.50.300 67 98 4.9E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01810 fee8578b02e6e26a92d173ddfc96e04b 449 Gene3D G3DSA:3.40.50.300 228 298 4.9E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01810 fee8578b02e6e26a92d173ddfc96e04b 449 Gene3D G3DSA:3.40.50.300 157 158 4.9E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02060 95475405c0c67e950622972e8a7c29a2 254 SUPERFAMILY SSF52096 3 226 1.13E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS02060 95475405c0c67e950622972e8a7c29a2 254 Gene3D G3DSA:3.90.226.10 3 240 1.1E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS02060 95475405c0c67e950622972e8a7c29a2 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 224 9.8E-44 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS02060 95475405c0c67e950622972e8a7c29a2 254 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 95 115 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:3.40.50.980 579 748 2.5E-46 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:3.40.50.980 1646 1796 6.0E-32 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SUPERFAMILY SSF56801 1605 2174 2.35E-141 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SUPERFAMILY SSF56801 571 1098 1.44E-143 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SMART SM00823 Phosphopantetheine attachment site 1087 1150 0.01 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SMART SM00823 Phosphopantetheine attachment site 2161 2230 6.2E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SMART SM00823 Phosphopantetheine attachment site 13 82 2.4E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1110 1125 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:3.40.50.980 1797 1951 2.3E-38 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF13745 HxxPF-repeated domain 1496 1593 1.4E-24 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF13745 HxxPF-repeated domain 437 533 3.3E-25 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF00975 Thioesterase domain 2245 2416 6.0E-27 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SUPERFAMILY SSF52777 1176 1350 4.78E-46 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF00668 Condensation domain 100 415 8.6E-56 T 06-07-2017 IPR001242 Condensation domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF00668 Condensation domain 1173 1474 2.1E-58 T 06-07-2017 IPR001242 Condensation domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 606 1003 1.2E-129 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1667 2076 1.8E-116 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SUPERFAMILY SSF53474 2231 2486 1.5E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF00550 Phosphopantetheine attachment site 1090 1145 3.9E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF00550 Phosphopantetheine attachment site 2165 2223 2.8E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF00550 Phosphopantetheine attachment site 16 75 5.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SUPERFAMILY SSF52777 103 291 2.78E-43 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SUPERFAMILY SSF52777 1363 1631 1.45E-58 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF00501 AMP-binding enzyme 1650 2052 2.0E-82 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF00501 AMP-binding enzyme 585 979 5.0E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SUPERFAMILY SSF47336 2154 2223 5.37E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:3.40.50.1820 2232 2349 1.4E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:3.40.50.1820 2423 2485 1.4E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:3.40.50.980 749 891 1.5E-34 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2185 2200 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SUPERFAMILY SSF47336 6 78 7.2E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SMART SM00824 Thioesterase 2248 2484 2.8E-4 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SUPERFAMILY SSF47336 1081 1149 7.33E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:2.30.38.10 1962 2042 1.0E-26 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:2.30.38.10 892 968 5.2E-27 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:1.10.1200.10 2166 2222 1.2E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:1.10.1200.10 1089 1151 8.0E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:1.10.1200.10 6 83 1.7E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 SUPERFAMILY SSF52777 303 553 4.34E-61 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 ProSitePatterns PS00455 Putative AMP-binding domain signature. 725 736 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:3.30.300.30 974 1088 9.8E-33 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Gene3D G3DSA:3.30.300.30 2047 2165 4.3E-36 T 06-07-2017 LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF13193 AMP-binding enzyme C-terminal domain 2060 2136 1.3E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS03265 b2dcacd96765c213a76b21fa8de488cf 2493 Pfam PF13193 AMP-binding enzyme C-terminal domain 987 1062 9.6E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS30715 137913295f75bfa2c5ee92b8012544b8 354 Gene3D G3DSA:1.10.540.10 5 86 4.0E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS30715 137913295f75bfa2c5ee92b8012544b8 354 Gene3D G3DSA:2.40.110.10 129 211 2.6E-5 T 06-07-2017 LK06_RS30715 137913295f75bfa2c5ee92b8012544b8 354 SUPERFAMILY SSF56645 8 211 2.75E-25 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS30715 137913295f75bfa2c5ee92b8012544b8 354 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 111 1.7E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 799 1.4E-26 T 06-07-2017 IPR019489 Clp ATPase, C-terminal LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 2.4E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 2.4E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 2.4E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 2.4E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Gene3D G3DSA:3.40.50.300 494 667 4.6E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Gene3D G3DSA:3.40.50.300 702 730 4.6E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 SUPERFAMILY SSF81923 3 144 3.43E-33 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Gene3D G3DSA:1.10.1780.10 1 143 3.1E-54 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 SUPERFAMILY SSF52540 490 801 3.08E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Gene3D G3DSA:1.10.8.60 350 432 1.6E-33 T 06-07-2017 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 SMART SM00382 541 691 1.7E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 SMART SM00382 204 348 5.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 SUPERFAMILY SSF52540 167 445 1.39E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 3.2E-19 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 4.5E-17 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 712 1.4E-54 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Gene3D G3DSA:1.10.8.60 731 816 3.1E-33 T 06-07-2017 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 329 1.1E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Gene3D G3DSA:3.40.50.300 167 347 5.1E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 Pfam PF02151 UvrB/uvrC motif 421 453 5.8E-7 T 06-07-2017 IPR001943 UVR domain GO:0005515 LK06_RS13650 931931c1a1d721c722381b65ec22f93e 841 SMART SM01086 719 810 1.2E-37 T 06-07-2017 IPR019489 Clp ATPase, C-terminal LK06_RS14915 aa2b3939dd0bcbb4d701b05a565970e1 459 SUPERFAMILY SSF48264 10 402 8.64E-54 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14915 aa2b3939dd0bcbb4d701b05a565970e1 459 Gene3D G3DSA:1.10.630.10 9 403 1.8E-65 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14915 aa2b3939dd0bcbb4d701b05a565970e1 459 PRINTS PR00359 B-class P450 signature 204 226 1.6E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14915 aa2b3939dd0bcbb4d701b05a565970e1 459 PRINTS PR00359 B-class P450 signature 108 119 1.6E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14915 aa2b3939dd0bcbb4d701b05a565970e1 459 PRINTS PR00359 B-class P450 signature 156 172 1.6E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14915 aa2b3939dd0bcbb4d701b05a565970e1 459 PRINTS PR00359 B-class P450 signature 294 321 1.6E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14915 aa2b3939dd0bcbb4d701b05a565970e1 459 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 41.638 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 SUPERFAMILY SSF52029 184 374 1.5E-82 T 06-07-2017 IPR027409 GroEL-like apical domain LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 2.0E-250 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 Gene3D G3DSA:3.50.7.10 195 368 2.8E-93 T 06-07-2017 IPR027409 GroEL-like apical domain LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 PRINTS PR00298 60kDa chaperonin signature 348 373 3.8E-70 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 PRINTS PR00298 60kDa chaperonin signature 26 52 3.8E-70 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 PRINTS PR00298 60kDa chaperonin signature 82 109 3.8E-70 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 PRINTS PR00298 60kDa chaperonin signature 266 289 3.8E-70 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 PRINTS PR00298 60kDa chaperonin signature 396 417 3.8E-70 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 Gene3D G3DSA:1.10.560.10 6 194 2.4E-48 T 06-07-2017 IPR027413 GroEL-like equatorial domain LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.4E-97 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 Gene3D G3DSA:1.10.560.10 369 515 2.3E-39 T 06-07-2017 IPR027413 GroEL-like equatorial domain LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 SUPERFAMILY SSF48592 6 133 3.16E-75 T 06-07-2017 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 SUPERFAMILY SSF48592 404 518 3.16E-75 T 06-07-2017 LK06_RS18300 50cb403e3e26a0907a11a83414c9afa9 541 SUPERFAMILY SSF54849 137 202 6.18E-27 T 06-07-2017 LK06_RS24995 a41c1ec5f0e2c4f915539fae4643ff05 181 Pfam PF02464 Competence-damaged protein 5 161 7.1E-48 T 06-07-2017 IPR008136 CinA, C-terminal LK06_RS24995 a41c1ec5f0e2c4f915539fae4643ff05 181 Gene3D G3DSA:3.90.950.20 4 163 1.7E-57 T 06-07-2017 IPR008136 CinA, C-terminal LK06_RS24995 a41c1ec5f0e2c4f915539fae4643ff05 181 SUPERFAMILY SSF142433 4 162 9.29E-46 T 06-07-2017 IPR008136 CinA, C-terminal LK06_RS24995 a41c1ec5f0e2c4f915539fae4643ff05 181 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 11 161 1.6E-35 T 06-07-2017 IPR008136 CinA, C-terminal LK06_RS02275 37893925adcc95a2c1d0ac86cd6f1fb5 405 Gene3D G3DSA:3.90.1150.10 6 64 9.8E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS02275 37893925adcc95a2c1d0ac86cd6f1fb5 405 Gene3D G3DSA:3.90.1150.10 314 404 9.8E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS02275 37893925adcc95a2c1d0ac86cd6f1fb5 405 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS02275 37893925adcc95a2c1d0ac86cd6f1fb5 405 Pfam PF00202 Aminotransferase class-III 22 404 2.4E-112 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS02275 37893925adcc95a2c1d0ac86cd6f1fb5 405 SUPERFAMILY SSF53383 8 404 1.67E-117 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS02275 37893925adcc95a2c1d0ac86cd6f1fb5 405 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 11 404 2.5E-147 T 06-07-2017 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LK06_RS02275 37893925adcc95a2c1d0ac86cd6f1fb5 405 Gene3D G3DSA:3.40.640.10 65 310 7.4E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS14375 cecb5e77bcb36d7ef21e8db2a95ea23f 450 SUPERFAMILY SSF142984 254 332 1.83E-13 T 06-07-2017 LK06_RS14375 cecb5e77bcb36d7ef21e8db2a95ea23f 450 SUPERFAMILY SSF142019 51 252 6.8E-41 T 06-07-2017 LK06_RS14375 cecb5e77bcb36d7ef21e8db2a95ea23f 450 SUPERFAMILY SSF140490 336 433 2.48E-15 T 06-07-2017 LK06_RS14375 cecb5e77bcb36d7ef21e8db2a95ea23f 450 Pfam PF10531 SLBB domain 254 296 7.6E-9 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS14375 cecb5e77bcb36d7ef21e8db2a95ea23f 450 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 341 423 3.5E-14 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS14375 cecb5e77bcb36d7ef21e8db2a95ea23f 450 SMART SM00928 338 383 0.0039 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS14375 cecb5e77bcb36d7ef21e8db2a95ea23f 450 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 70 230 5.8E-34 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 SMART SM00382 26 232 3.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 SMART SM00382 350 515 4.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 Pfam PF00005 ABC transporter 342 471 6.5E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 Pfam PF00005 ABC transporter 19 187 5.6E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 Gene3D G3DSA:3.40.50.300 328 516 1.6E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 Gene3D G3DSA:3.40.50.300 5 102 7.4E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 Gene3D G3DSA:3.40.50.300 135 279 7.4E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 SUPERFAMILY SSF52540 330 517 2.48E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 Pfam PF12848 ABC transporter 230 307 1.0E-6 T 06-07-2017 IPR032781 ABC-transporter extension domain LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 SUPERFAMILY SSF52540 2 79 3.39E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06190 dd116257e7c1e15062a684fbbf03b067 532 SUPERFAMILY SSF52540 128 234 3.39E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 Gene3D G3DSA:1.20.1560.10 17 327 8.2E-64 T 06-07-2017 LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 Gene3D G3DSA:1.20.1560.10 670 988 1.9E-75 T 06-07-2017 LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 Pfam PF00005 ABC transporter 360 509 1.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 Pfam PF00005 ABC transporter 1015 1163 1.9E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 ProSitePatterns PS00211 ABC transporters family signature. 1135 1149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 Pfam PF00664 ABC transporter transmembrane region 32 299 6.9E-36 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 Pfam PF00664 ABC transporter transmembrane region 681 952 7.6E-38 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 Gene3D G3DSA:3.40.50.300 343 572 1.4E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 Gene3D G3DSA:3.40.50.300 998 1228 6.0E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 SUPERFAMILY SSF90123 17 327 2.88E-67 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 SUPERFAMILY SSF90123 670 979 4.84E-71 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 SUPERFAMILY SSF52540 989 1232 1.57E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 SUPERFAMILY SSF52540 338 576 9.67E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 SMART SM00382 369 555 1.6E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS10655 7df92389fb98135c6d3811440791ac8d 1247 SMART SM00382 1023 1209 2.4E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS01170 90ef4a13be937047479883aa66d7ab72 62 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.1E-8 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS01170 90ef4a13be937047479883aa66d7ab72 62 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.1E-8 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS01170 90ef4a13be937047479883aa66d7ab72 62 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 2.1E-8 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS01170 90ef4a13be937047479883aa66d7ab72 62 Pfam PF13459 4Fe-4S single cluster domain 3 61 1.9E-14 T 06-07-2017 LK06_RS01170 90ef4a13be937047479883aa66d7ab72 62 SUPERFAMILY SSF54862 2 61 2.55E-12 T 06-07-2017 LK06_RS01170 90ef4a13be937047479883aa66d7ab72 62 Gene3D G3DSA:3.30.70.20 1 61 4.4E-16 T 06-07-2017 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 414 40.601 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 SUPERFAMILY SSF52440 2 101 2.88E-30 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 9.7E-30 T 06-07-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 SUPERFAMILY SSF51246 317 413 6.8E-27 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 SUPERFAMILY SSF56059 102 309 6.72E-55 T 06-07-2017 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 Gene3D G3DSA:3.30.470.20 179 316 1.9E-56 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 SMART SM01209 101 283 5.2E-115 T 06-07-2017 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 Gene3D G3DSA:3.40.50.20 2 93 7.9E-32 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 319 411 3.8E-28 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 283 5.1E-65 T 06-07-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 SMART SM01210 318 414 1.9E-47 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 Gene3D G3DSA:3.30.1490.20 122 178 1.5E-16 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 Gene3D G3DSA:3.90.600.10 318 413 4.6E-33 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 414 3.4E-145 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LK06_RS16955 ce84c0f7bf0e8fb8cae6b28dd5278ac6 419 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 277 284 - T 06-07-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LK06_RS00535 4739f3f65b662091cd3b664635dd4f0f 186 Pfam PF04982 HPP family 53 173 1.3E-14 T 06-07-2017 IPR007065 HPP LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 Pfam PF00067 Cytochrome P450 276 373 5.3E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 SUPERFAMILY SSF48264 9 404 1.7E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 PRINTS PR00359 B-class P450 signature 143 159 3.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 PRINTS PR00359 B-class P450 signature 323 338 3.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 PRINTS PR00359 B-class P450 signature 344 353 3.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 PRINTS PR00359 B-class P450 signature 160 175 3.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 PRINTS PR00359 B-class P450 signature 96 107 3.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 PRINTS PR00359 B-class P450 signature 353 364 3.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 PRINTS PR00359 B-class P450 signature 295 322 3.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 PRINTS PR00359 B-class P450 signature 197 219 3.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 PRINTS PR00359 B-class P450 signature 276 287 3.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 Gene3D G3DSA:1.10.630.10 23 404 5.7E-107 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02210 e4f4f0b03e277c6c1832a69db34c67b3 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS00310 10eaa16c06db48055bf4f44c472416a2 224 Pfam PF00571 CBS domain 89 141 4.4E-14 T 06-07-2017 IPR000644 CBS domain LK06_RS00310 10eaa16c06db48055bf4f44c472416a2 224 Pfam PF00571 CBS domain 6 60 9.5E-14 T 06-07-2017 IPR000644 CBS domain LK06_RS00310 10eaa16c06db48055bf4f44c472416a2 224 PIRSF PIRSF036990 4 220 1.5E-58 T 06-07-2017 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON LK06_RS00310 10eaa16c06db48055bf4f44c472416a2 224 SMART SM00116 95 143 7.4E-10 T 06-07-2017 IPR000644 CBS domain LK06_RS00310 10eaa16c06db48055bf4f44c472416a2 224 SMART SM00116 13 61 1.6E-9 T 06-07-2017 IPR000644 CBS domain LK06_RS00310 10eaa16c06db48055bf4f44c472416a2 224 SUPERFAMILY SSF54631 1 141 6.41E-34 T 06-07-2017 LK06_RS00310 10eaa16c06db48055bf4f44c472416a2 224 Gene3D G3DSA:3.10.580.10 5 143 9.5E-33 T 06-07-2017 LK06_RS00310 10eaa16c06db48055bf4f44c472416a2 224 Pfam PF04972 BON domain 146 213 1.9E-9 T 06-07-2017 IPR007055 BON domain LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 Gene3D G3DSA:3.40.50.80 263 388 4.1E-28 T 06-07-2017 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 SUPERFAMILY SSF52343 261 387 3.01E-32 T 06-07-2017 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 Gene3D G3DSA:1.10.490.10 2 145 3.5E-45 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 Gene3D G3DSA:2.40.30.10 152 257 1.6E-32 T 06-07-2017 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 Pfam PF00042 Globin 8 104 4.4E-8 T 06-07-2017 IPR000971 Globin GO:0019825|GO:0020037 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 SUPERFAMILY SSF46458 1 148 2.16E-34 T 06-07-2017 IPR009050 Globin-like LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 SUPERFAMILY SSF63380 152 257 7.88E-28 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 267 286 4.7E-10 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 292 301 4.7E-10 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 353 361 4.7E-10 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 183 195 4.7E-10 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 Pfam PF00175 Oxidoreductase NAD-binding domain 270 367 2.4E-12 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LK06_RS08145 bde732acf108aa1e042f36dd3c90271a 396 Pfam PF00970 Oxidoreductase FAD-binding domain 156 256 4.8E-12 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 LK06_RS05790 f0dc3a5b3bd99624bdd986e550017fca 347 Pfam PF01032 FecCD transport family 35 341 4.0E-88 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 LK06_RS05790 f0dc3a5b3bd99624bdd986e550017fca 347 SUPERFAMILY SSF81345 23 342 3.27E-77 T 06-07-2017 IPR029022 ABC transporter, BtuC-like LK06_RS05790 f0dc3a5b3bd99624bdd986e550017fca 347 Gene3D G3DSA:1.10.3470.10 27 344 4.8E-95 T 06-07-2017 IPR029022 ABC transporter, BtuC-like LK06_RS00655 d02aaa4db5e7c5a60e21106bedd09708 404 SMART SM00495 357 401 2.4E-11 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS00655 d02aaa4db5e7c5a60e21106bedd09708 404 Pfam PF02839 Carbohydrate binding domain 360 398 2.6E-10 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS00655 d02aaa4db5e7c5a60e21106bedd09708 404 SUPERFAMILY SSF51445 52 303 2.11E-18 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS00655 d02aaa4db5e7c5a60e21106bedd09708 404 SUPERFAMILY SSF51055 349 404 1.24E-13 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS00655 d02aaa4db5e7c5a60e21106bedd09708 404 Gene3D G3DSA:2.10.10.20 355 404 8.2E-16 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS00655 d02aaa4db5e7c5a60e21106bedd09708 404 Gene3D G3DSA:3.20.20.80 91 307 1.6E-14 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS27060 f5238ad094a7d7880bd7dcbdfe55d272 416 Gene3D G3DSA:3.30.420.40 79 219 3.3E-40 T 06-07-2017 LK06_RS27060 f5238ad094a7d7880bd7dcbdfe55d272 416 SUPERFAMILY SSF53067 80 389 3.84E-56 T 06-07-2017 LK06_RS27060 f5238ad094a7d7880bd7dcbdfe55d272 416 ProSitePatterns PS01125 ROK family signature. 215 242 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS27060 f5238ad094a7d7880bd7dcbdfe55d272 416 Gene3D G3DSA:1.10.10.10 7 75 2.6E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27060 f5238ad094a7d7880bd7dcbdfe55d272 416 Gene3D G3DSA:3.30.420.40 220 372 2.7E-48 T 06-07-2017 LK06_RS27060 f5238ad094a7d7880bd7dcbdfe55d272 416 SUPERFAMILY SSF46785 8 69 1.49E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27060 f5238ad094a7d7880bd7dcbdfe55d272 416 Pfam PF00480 ROK family 82 386 1.6E-53 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 SUPERFAMILY SSF52540 6 75 6.36E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 SUPERFAMILY SSF52540 126 226 6.36E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 950 962 7.3E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 920 934 7.3E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 934 950 7.3E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 SUPERFAMILY SSF48452 533 664 3.48E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 Pfam PF00196 Bacterial regulatory proteins, luxR family 919 974 1.2E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 Gene3D G3DSA:1.10.10.10 912 979 1.8E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 SMART SM00421 917 974 1.7E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 Pfam PF13191 AAA ATPase domain 10 166 1.1E-28 T 06-07-2017 LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 Gene3D G3DSA:3.40.50.300 10 74 7.9E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 Gene3D G3DSA:3.40.50.300 118 202 7.9E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 SUPERFAMILY SSF46894 914 981 2.24E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 Gene3D G3DSA:1.25.40.10 531 679 2.0E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS30880 edd0b0979ac60e2665496b799a407027 988 Gene3D G3DSA:1.25.40.10 850 887 2.0E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 Gene3D G3DSA:3.30.565.10 345 486 1.7E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 Pfam PF07568 Histidine kinase 290 360 1.6E-22 T 06-07-2017 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 Gene3D G3DSA:3.30.450.20 172 272 3.4E-7 T 06-07-2017 LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 1.2E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 1.2E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 1.2E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 Pfam PF12282 Signal transduction histidine kinase 1 144 8.5E-61 T 06-07-2017 IPR022066 Signal transduction histidine kinase LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 SUPERFAMILY SSF55785 173 281 3.24E-7 T 06-07-2017 IPR000014 PAS domain LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 SUPERFAMILY SSF55874 345 484 5.37E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 Pfam PF08448 PAS fold 171 276 2.1E-14 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 484 1.7E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22455 788fdb4e970ee2db3d70b1b54ed11756 488 SMART SM00387 382 486 2.3E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04465 c611f65867661ccb22a1d3da3a51da44 150 Gene3D G3DSA:3.30.530.20 5 135 2.0E-14 T 06-07-2017 IPR023393 START-like domain LK06_RS04465 c611f65867661ccb22a1d3da3a51da44 150 SUPERFAMILY SSF55961 6 138 9.36E-16 T 06-07-2017 LK06_RS04465 c611f65867661ccb22a1d3da3a51da44 150 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 14 120 4.5E-12 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain LK06_RS15440 ff9a0851957ed840f9d6cf8037d99f11 448 Gene3D G3DSA:4.10.320.10 156 202 1.6E-15 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS15440 ff9a0851957ed840f9d6cf8037d99f11 448 SUPERFAMILY SSF47005 154 196 3.92E-10 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS15440 ff9a0851957ed840f9d6cf8037d99f11 448 Gene3D G3DSA:2.40.50.100 3 86 3.1E-25 T 06-07-2017 LK06_RS15440 ff9a0851957ed840f9d6cf8037d99f11 448 SUPERFAMILY SSF51230 3 87 1.31E-24 T 06-07-2017 IPR011053 Single hybrid motif LK06_RS15440 ff9a0851957ed840f9d6cf8037d99f11 448 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 222 445 9.1E-71 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS15440 ff9a0851957ed840f9d6cf8037d99f11 448 Pfam PF00364 Biotin-requiring enzyme 6 77 4.7E-17 T 06-07-2017 IPR000089 Biotin/lipoyl attachment LK06_RS15440 ff9a0851957ed840f9d6cf8037d99f11 448 Pfam PF02817 e3 binding domain 159 193 2.2E-13 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS15440 ff9a0851957ed840f9d6cf8037d99f11 448 SUPERFAMILY SSF52777 214 445 5.78E-71 T 06-07-2017 LK06_RS15440 ff9a0851957ed840f9d6cf8037d99f11 448 Gene3D G3DSA:3.30.559.10 212 445 5.5E-74 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 LK06_RS25835 ff8bfa2b52591cc65611dea07cc74fe3 183 Gene3D G3DSA:2.60.120.10 8 179 6.7E-61 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS25835 ff8bfa2b52591cc65611dea07cc74fe3 183 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 182 9.0E-86 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 LK06_RS25835 ff8bfa2b52591cc65611dea07cc74fe3 183 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 176 4.2E-55 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 LK06_RS25835 ff8bfa2b52591cc65611dea07cc74fe3 183 SUPERFAMILY SSF51182 8 178 7.63E-58 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS25835 ff8bfa2b52591cc65611dea07cc74fe3 183 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 8 177 1.1E-47 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 LK06_RS02445 2ebbac98ec8e4cc4d7eb4eb994d2a4ca 112 SUPERFAMILY SSF55681 30 104 6.46E-19 T 06-07-2017 LK06_RS02445 2ebbac98ec8e4cc4d7eb4eb994d2a4ca 112 Gene3D G3DSA:3.30.930.10 31 104 1.6E-19 T 06-07-2017 LK06_RS02445 2ebbac98ec8e4cc4d7eb4eb994d2a4ca 112 Pfam PF01411 tRNA synthetases class II (A) 32 105 2.4E-17 T 06-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 Gene3D G3DSA:3.40.1190.10 84 313 6.0E-69 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 Pfam PF08245 Mur ligase middle domain 108 297 9.2E-48 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 SUPERFAMILY SSF63418 4 98 3.14E-20 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 459 1.6E-129 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 Pfam PF01225 Mur ligase family, catalytic domain 34 94 3.5E-8 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 SUPERFAMILY SSF53623 102 313 3.92E-53 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 399 3.5E-20 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 Gene3D G3DSA:3.90.190.20 319 461 2.8E-42 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 SUPERFAMILY SSF53244 320 459 8.97E-35 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 460 32.409 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS07320 c8bc273863873e9a6998c4722d087cea 471 Gene3D G3DSA:3.40.1390.10 3 81 2.9E-20 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LK06_RS24750 aa33d8fab1e5f7ce97dbb16b3b458a81 169 Gene3D G3DSA:3.30.300.70 3 82 2.0E-19 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal LK06_RS24750 aa33d8fab1e5f7ce97dbb16b3b458a81 169 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 155 19.217 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 LK06_RS24750 aa33d8fab1e5f7ce97dbb16b3b458a81 169 SUPERFAMILY SSF75420 3 85 9.94E-18 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal LK06_RS24750 aa33d8fab1e5f7ce97dbb16b3b458a81 169 Pfam PF02576 Putative ribosome maturation factor RimP 12 151 4.6E-33 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 LK06_RS07990 fe0ee394bc6b1974d1ec4d2c3f8a0f7f 348 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 197 346 1.6E-30 T 06-07-2017 IPR020051 SagB-type dehydrogenase domain LK06_RS07990 fe0ee394bc6b1974d1ec4d2c3f8a0f7f 348 Gene3D G3DSA:3.40.109.10 149 340 8.1E-21 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS07990 fe0ee394bc6b1974d1ec4d2c3f8a0f7f 348 Pfam PF00881 Nitroreductase family 155 342 2.7E-20 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 LK06_RS07990 fe0ee394bc6b1974d1ec4d2c3f8a0f7f 348 SUPERFAMILY SSF55469 152 347 1.57E-23 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 2.2E-17 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 2.2E-17 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 PRINTS PR00149 Fumarate lyase superfamily signature 298 314 2.2E-17 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 PRINTS PR00149 Fumarate lyase superfamily signature 253 280 2.2E-17 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 Pfam PF00206 Lyase 27 321 9.5E-32 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 SUPERFAMILY SSF48557 26 467 2.98E-93 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 Pfam PF10397 Adenylosuccinate lyase C-terminus 387 463 8.9E-11 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 Gene3D G3DSA:1.20.200.10 109 391 6.4E-88 T 06-07-2017 LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 SMART SM00998 386 465 2.9E-16 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 Gene3D G3DSA:1.10.275.10 17 108 1.5E-28 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 18 371 1.5E-108 T 06-07-2017 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 LK06_RS29165 08af6392bcf864d4fe4bcdc7c5d8e1ae 491 Gene3D G3DSA:1.10.40.30 392 464 3.7E-18 T 06-07-2017 LK06_RS25815 2123f8fb3c73e11a1156b99bfe749b2c 47 Gene3D G3DSA:3.40.50.2300 3 44 8.3E-7 T 06-07-2017 LK06_RS25815 2123f8fb3c73e11a1156b99bfe749b2c 47 SUPERFAMILY SSF52172 4 44 8.54E-7 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS24085 569c023f54c523f9c97094704885ace1 189 Pfam PF05331 Protein of unknown function (DUF742) 77 189 1.2E-41 T 06-07-2017 IPR007995 Protein of unknown function DUF742 LK06_RS29700 1602c9ccde27ffa349c2bc5ea5886d8c 600 Pfam PF00664 ABC transporter transmembrane region 38 310 5.4E-35 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS29700 1602c9ccde27ffa349c2bc5ea5886d8c 600 Gene3D G3DSA:3.40.50.300 357 587 4.6E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29700 1602c9ccde27ffa349c2bc5ea5886d8c 600 SUPERFAMILY SSF52540 346 591 8.63E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29700 1602c9ccde27ffa349c2bc5ea5886d8c 600 Gene3D G3DSA:1.20.1560.10 23 343 3.7E-64 T 06-07-2017 LK06_RS29700 1602c9ccde27ffa349c2bc5ea5886d8c 600 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS29700 1602c9ccde27ffa349c2bc5ea5886d8c 600 SMART SM00382 383 569 2.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS29700 1602c9ccde27ffa349c2bc5ea5886d8c 600 SUPERFAMILY SSF90123 19 345 1.57E-65 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS29700 1602c9ccde27ffa349c2bc5ea5886d8c 600 Pfam PF00005 ABC transporter 374 523 4.0E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS11065 a7b61bc6228cb9c45644f8e34924eade 294 SUPERFAMILY SSF48498 152 266 1.13E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS11065 a7b61bc6228cb9c45644f8e34924eade 294 SUPERFAMILY SSF46689 71 146 5.49E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS11065 a7b61bc6228cb9c45644f8e34924eade 294 Pfam PF00440 Bacterial regulatory proteins, tetR family 85 131 2.3E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS11065 a7b61bc6228cb9c45644f8e34924eade 294 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 106 129 3.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS11065 a7b61bc6228cb9c45644f8e34924eade 294 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 85 98 3.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS11065 a7b61bc6228cb9c45644f8e34924eade 294 Gene3D G3DSA:1.10.357.10 70 267 8.9E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS27050 af090b69e7999d3cbf180b1cc87e8ab1 96 Gene3D G3DSA:3.30.70.900 1 96 6.4E-31 T 06-07-2017 LK06_RS27050 af090b69e7999d3cbf180b1cc87e8ab1 96 SUPERFAMILY SSF54909 1 96 1.74E-26 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS27050 af090b69e7999d3cbf180b1cc87e8ab1 96 Pfam PF07045 Domain of unknown function (DUF1330) 2 96 3.2E-30 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 LK06_RS05510 bd7fa5625447f7384b1aca4f160fcb12 320 SUPERFAMILY SSF81296 33 214 3.36E-49 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS05510 bd7fa5625447f7384b1aca4f160fcb12 320 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 33 210 5.9E-40 T 06-07-2017 IPR004302 Chitin-binding protein, N-terminal LK06_RS05510 bd7fa5625447f7384b1aca4f160fcb12 320 Gene3D G3DSA:2.70.50.50 33 213 1.1E-51 T 06-07-2017 LK06_RS03135 bba86caf56c4fb9715e8004dd817e5ca 525 PIRSF PIRSF002741 13 519 2.9E-66 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LK06_RS03135 bba86caf56c4fb9715e8004dd817e5ca 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 438 1.3E-74 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS03135 bba86caf56c4fb9715e8004dd817e5ca 525 Gene3D G3DSA:3.10.105.10 291 490 1.2E-41 T 06-07-2017 LK06_RS03135 bba86caf56c4fb9715e8004dd817e5ca 525 Gene3D G3DSA:3.40.190.10 140 290 3.5E-34 T 06-07-2017 LK06_RS03135 bba86caf56c4fb9715e8004dd817e5ca 525 SUPERFAMILY SSF53850 31 522 2.5E-99 T 06-07-2017 LK06_RS19125 54ad5f3f2ec9b5ea2ed8a8c934839dc7 477 Gene3D G3DSA:3.30.200.20 2 87 7.2E-28 T 06-07-2017 LK06_RS19125 54ad5f3f2ec9b5ea2ed8a8c934839dc7 477 Gene3D G3DSA:1.10.510.10 88 260 2.6E-45 T 06-07-2017 LK06_RS19125 54ad5f3f2ec9b5ea2ed8a8c934839dc7 477 Pfam PF00069 Protein kinase domain 7 258 2.2E-49 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS19125 54ad5f3f2ec9b5ea2ed8a8c934839dc7 477 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 13 36 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS19125 54ad5f3f2ec9b5ea2ed8a8c934839dc7 477 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS19125 54ad5f3f2ec9b5ea2ed8a8c934839dc7 477 SUPERFAMILY SSF56112 3 268 2.23E-74 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS19125 54ad5f3f2ec9b5ea2ed8a8c934839dc7 477 SMART SM00220 7 273 9.3E-62 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS00050 23afc3a8ab52f319bfaac4c042cdcc94 270 SMART SM00382 31 217 3.2E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS00050 23afc3a8ab52f319bfaac4c042cdcc94 270 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS00050 23afc3a8ab52f319bfaac4c042cdcc94 270 SUPERFAMILY SSF52540 5 227 4.05E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00050 23afc3a8ab52f319bfaac4c042cdcc94 270 Gene3D G3DSA:3.40.50.300 5 224 6.2E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00050 23afc3a8ab52f319bfaac4c042cdcc94 270 Pfam PF00005 ABC transporter 22 162 3.5E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS04090 3afddcb6ffe3efaec5f1812dacc6ac2f 185 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 182 2.5E-69 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 LK06_RS04090 3afddcb6ffe3efaec5f1812dacc6ac2f 185 Hamap MF_00328 Guanylate kinase [gmk]. 3 185 34.081 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 LK06_RS04090 3afddcb6ffe3efaec5f1812dacc6ac2f 185 SUPERFAMILY SSF52540 4 183 4.2E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04090 3afddcb6ffe3efaec5f1812dacc6ac2f 185 Gene3D G3DSA:3.40.50.300 16 43 7.9E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04090 3afddcb6ffe3efaec5f1812dacc6ac2f 185 Gene3D G3DSA:3.30.63.10 44 86 1.2E-28 T 06-07-2017 LK06_RS04090 3afddcb6ffe3efaec5f1812dacc6ac2f 185 Pfam PF00625 Guanylate kinase 5 182 6.0E-46 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit LK06_RS04090 3afddcb6ffe3efaec5f1812dacc6ac2f 185 SMART SM00072 4 185 4.8E-62 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit LK06_RS04090 3afddcb6ffe3efaec5f1812dacc6ac2f 185 ProSitePatterns PS00856 Guanylate kinase-like signature. 39 56 - T 06-07-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 LK06_RS04090 3afddcb6ffe3efaec5f1812dacc6ac2f 185 Gene3D G3DSA:3.40.50.300 3 15 1.9E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04090 3afddcb6ffe3efaec5f1812dacc6ac2f 185 Gene3D G3DSA:3.40.50.300 87 182 1.9E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18190 420caf2c9d86ab6f5c33c8667f8a8bf1 459 Pfam PF01433 Peptidase family M1 310 351 1.4E-14 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS18190 420caf2c9d86ab6f5c33c8667f8a8bf1 459 Pfam PF01433 Peptidase family M1 49 277 1.1E-19 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS18190 420caf2c9d86ab6f5c33c8667f8a8bf1 459 Gene3D G3DSA:1.10.390.10 323 456 4.9E-18 T 06-07-2017 LK06_RS18190 420caf2c9d86ab6f5c33c8667f8a8bf1 459 SUPERFAMILY SSF55486 235 456 5.86E-45 T 06-07-2017 LK06_RS18190 420caf2c9d86ab6f5c33c8667f8a8bf1 459 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 309 324 1.5E-10 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS18190 420caf2c9d86ab6f5c33c8667f8a8bf1 459 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 328 340 1.5E-10 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS18190 420caf2c9d86ab6f5c33c8667f8a8bf1 459 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 163 178 1.5E-10 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS18190 420caf2c9d86ab6f5c33c8667f8a8bf1 459 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 210 225 1.5E-10 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS18190 420caf2c9d86ab6f5c33c8667f8a8bf1 459 SUPERFAMILY SSF63737 32 227 5.23E-40 T 06-07-2017 LK06_RS12290 439450c7d0fc7adc8193d313d31decce 115 ProSitePatterns PS00464 Ribosomal protein L22 signature. 84 108 - T 06-07-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12290 439450c7d0fc7adc8193d313d31decce 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 108 2.2E-45 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12290 439450c7d0fc7adc8193d313d31decce 115 Pfam PF00237 Ribosomal protein L22p/L17e 8 108 3.9E-33 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 LK06_RS12290 439450c7d0fc7adc8193d313d31decce 115 Gene3D G3DSA:3.90.470.10 1 112 1.9E-42 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 LK06_RS12290 439450c7d0fc7adc8193d313d31decce 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 111 30.164 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12290 439450c7d0fc7adc8193d313d31decce 115 SUPERFAMILY SSF54843 1 112 2.35E-42 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 SUPERFAMILY SSF56672 153 436 2.0E-60 T 06-07-2017 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 SUPERFAMILY SSF56672 471 570 2.0E-60 T 06-07-2017 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 PRINTS PR00868 DNA-polymerase family A (pol I) signature 485 501 1.9E-6 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 PRINTS PR00868 DNA-polymerase family A (pol I) signature 513 526 1.9E-6 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 PRINTS PR00868 DNA-polymerase family A (pol I) signature 325 348 1.9E-6 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 Pfam PF00476 DNA polymerase family A 205 545 2.9E-27 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 SMART SM00482 311 530 1.9E-11 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 Gene3D G3DSA:3.30.70.370 294 333 1.3E-11 T 06-07-2017 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 Gene3D G3DSA:3.30.70.370 493 564 1.3E-11 T 06-07-2017 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 Gene3D G3DSA:1.10.150.20 469 492 8.9E-20 T 06-07-2017 LK06_RS13905 75d68658e6ab0420f3b7f9bfe60208f1 571 Gene3D G3DSA:1.10.150.20 334 431 8.9E-20 T 06-07-2017 LK06_RS27435 d042cd1361f12836bf00f9fc77256f5f 199 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 195 6.3E-52 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS27435 d042cd1361f12836bf00f9fc77256f5f 199 SUPERFAMILY SSF53254 4 197 2.17E-50 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS27435 d042cd1361f12836bf00f9fc77256f5f 199 SMART SM00855 3 156 2.9E-24 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS27435 d042cd1361f12836bf00f9fc77256f5f 199 Gene3D G3DSA:3.40.50.1240 4 194 4.5E-49 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS07120 6122066ac2144f4b20b90fd88aec9005 132 Gene3D G3DSA:3.10.180.10 2 131 4.1E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS07120 6122066ac2144f4b20b90fd88aec9005 132 SUPERFAMILY SSF54593 4 130 2.82E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS07120 6122066ac2144f4b20b90fd88aec9005 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 127 2.2E-13 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS21830 3c6c58fb7009e9a74f5ac15f3722f1e8 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 324 3.5E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21830 3c6c58fb7009e9a74f5ac15f3722f1e8 326 Gene3D G3DSA:1.10.3720.10 99 316 1.0E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21830 3c6c58fb7009e9a74f5ac15f3722f1e8 326 SUPERFAMILY SSF161098 100 310 2.4E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS30285 503cdb93e738657a5fd837aaab53c119 410 Gene3D G3DSA:1.20.1250.20 194 392 3.3E-11 T 06-07-2017 LK06_RS30285 503cdb93e738657a5fd837aaab53c119 410 Pfam PF07690 Major Facilitator Superfamily 4 352 1.7E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS30285 503cdb93e738657a5fd837aaab53c119 410 Gene3D G3DSA:1.20.1250.20 3 177 3.9E-26 T 06-07-2017 LK06_RS30285 503cdb93e738657a5fd837aaab53c119 410 SUPERFAMILY SSF103473 4 393 3.92E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 SUPERFAMILY SSF52518 358 556 9.03E-63 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 SUPERFAMILY SSF52922 560 691 9.95E-42 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 Gene3D G3DSA:3.40.50.920 564 690 2.8E-49 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 SUPERFAMILY SSF52518 6 335 6.41E-105 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 ProSitePatterns PS00802 Transketolase signature 2. 491 507 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 TIGRFAM TIGR00232 tktlase_bact: transketolase 19 689 1.3E-246 T 06-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 Pfam PF02780 Transketolase, C-terminal domain 576 682 1.5E-10 T 06-07-2017 IPR033248 Transketolase, C-terminal domain LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 SMART SM00861 371 555 2.9E-62 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 Gene3D G3DSA:3.40.50.970 13 338 1.8E-111 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 Pfam PF02779 Transketolase, pyrimidine binding domain 370 534 7.5E-42 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 ProSitePatterns PS00801 Transketolase signature 1. 24 44 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 355 1.6E-138 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS06535 69c861cd1d28f5bab4b34819d9ba6727 702 Gene3D G3DSA:3.40.50.970 351 563 1.0E-71 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 SUPERFAMILY SSF51905 167 354 4.76E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 1.2E-5 T 06-07-2017 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 1.2E-5 T 06-07-2017 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 1.2E-5 T 06-07-2017 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 Gene3D G3DSA:3.50.50.60 124 348 4.3E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 Gene3D G3DSA:3.50.50.60 12 123 6.9E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 9.1E-12 T 06-07-2017 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 9.1E-12 T 06-07-2017 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 9.1E-12 T 06-07-2017 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 9.1E-12 T 06-07-2017 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 340 5.2E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30940 f865d1a9f54f4078cb4c29317b465513 464 SUPERFAMILY SSF51905 13 222 9.99E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 Pfam PF14520 Helix-hairpin-helix domain 71 129 4.7E-15 T 06-07-2017 LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 198 27.145 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 SUPERFAMILY SSF47781 65 132 5.44E-19 T 06-07-2017 IPR010994 RuvA domain 2-like LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 180 1.2E-39 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 SUPERFAMILY SSF50249 1 62 1.26E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 Gene3D G3DSA:1.10.8.10 146 201 7.9E-11 T 06-07-2017 LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 Pfam PF07499 RuvA, C-terminal domain 148 197 2.2E-10 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 SMART SM00278 72 91 50.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 SMART SM00278 107 126 0.05 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 Pfam PF01330 RuvA N terminal domain 1 61 1.7E-20 T 06-07-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 Gene3D G3DSA:2.40.50.140 1 64 1.5E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 Gene3D G3DSA:1.10.150.20 66 133 3.5E-26 T 06-07-2017 LK06_RS04285 964a5be774464e776255c6710cdbfd39 201 SUPERFAMILY SSF46929 147 199 1.15E-9 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 LK06_RS21955 188e9ad2e5081315b3d0cf069fff9e59 288 Pfam PF13371 Tetratricopeptide repeat 206 288 9.7E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS21955 188e9ad2e5081315b3d0cf069fff9e59 288 Pfam PF13369 Transglutaminase-like superfamily 58 204 6.0E-42 T 06-07-2017 IPR032698 Protein SirB1, N-terminal LK06_RS29360 a85626449e600de1f56f9fdda0944d03 457 SUPERFAMILY SSF53383 18 441 1.07E-124 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS29360 a85626449e600de1f56f9fdda0944d03 457 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 45 376 1.2E-67 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 LK06_RS29360 a85626449e600de1f56f9fdda0944d03 457 Gene3D G3DSA:3.40.640.10 72 321 5.4E-29 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS29360 a85626449e600de1f56f9fdda0944d03 457 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 28 441 8.8E-173 T 06-07-2017 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 LK06_RS26240 3088d939564fc3d99724d1256d925346 340 SUPERFAMILY SSF110849 22 106 1.24E-8 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS26240 3088d939564fc3d99724d1256d925346 340 SMART SM00470 25 109 1.5E-8 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS26240 3088d939564fc3d99724d1256d925346 340 Gene3D G3DSA:1.10.10.60 189 240 2.2E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS26240 3088d939564fc3d99724d1256d925346 340 Gene3D G3DSA:3.90.1530.10 27 110 5.2E-8 T 06-07-2017 LK06_RS26240 3088d939564fc3d99724d1256d925346 340 Pfam PF02195 ParB-like nuclease domain 27 108 1.4E-7 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 72 294 1.8E-92 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 SUPERFAMILY SSF88659 213 294 2.8E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 Pfam PF04539 Sigma-70 region 3 157 223 3.0E-15 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 PRINTS PR00046 Major sigma-70 factor signature 101 114 3.1E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 PRINTS PR00046 Major sigma-70 factor signature 264 279 3.1E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 PRINTS PR00046 Major sigma-70 factor signature 247 259 3.1E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 SUPERFAMILY SSF88946 39 146 1.51E-31 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 Gene3D G3DSA:1.10.10.10 145 200 4.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 Gene3D G3DSA:1.10.601.10 58 144 2.2E-25 T 06-07-2017 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 Pfam PF04545 Sigma-70, region 4 244 292 3.8E-16 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 Pfam PF04542 Sigma-70 region 2 77 146 4.4E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 SUPERFAMILY SSF88659 150 225 1.05E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 74 293 9.3E-31 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 Gene3D G3DSA:1.10.10.10 240 294 7.9E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12065 165e69bacf00d25ba244e41ccecf25fd 298 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 101 114 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 487 7.4E-157 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 Pfam PF00571 CBS domain 157 212 1.2E-5 T 06-07-2017 IPR000644 CBS domain LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 Pfam PF00571 CBS domain 101 148 1.3E-8 T 06-07-2017 IPR000644 CBS domain LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 16 500 82.745 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 16 468 1.4E-182 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 SMART SM00116 104 152 2.4E-7 T 06-07-2017 IPR000644 CBS domain LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 SMART SM00116 165 213 1.9E-7 T 06-07-2017 IPR000644 CBS domain LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 SMART SM01240 15 487 0.0 T 06-07-2017 LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 Gene3D G3DSA:3.20.20.70 12 499 6.5E-196 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 302 314 - T 06-07-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 SUPERFAMILY SSF51412 11 98 2.49E-118 T 06-07-2017 LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 SUPERFAMILY SSF51412 224 491 2.49E-118 T 06-07-2017 LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 SUPERFAMILY SSF54631 75 211 1.17E-29 T 06-07-2017 LK06_RS20160 7c9ae7caa7006ecf7f71a7c896e0321b 502 PIRSF PIRSF000130 8 502 4.4E-202 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 LK06_RS02235 052944bd69d21eb823b570fe5ee31e61 179 Hamap MF_00163 Peptide deformylase [def]. 12 175 26.86 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS02235 052944bd69d21eb823b570fe5ee31e61 179 Pfam PF01327 Polypeptide deformylase 16 162 8.7E-42 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS02235 052944bd69d21eb823b570fe5ee31e61 179 SUPERFAMILY SSF56420 12 170 1.28E-51 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS02235 052944bd69d21eb823b570fe5ee31e61 179 PIRSF PIRSF004749 7 178 2.8E-40 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS02235 052944bd69d21eb823b570fe5ee31e61 179 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 20 166 2.0E-35 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS02235 052944bd69d21eb823b570fe5ee31e61 179 Gene3D G3DSA:3.90.45.10 16 177 1.7E-55 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS02235 052944bd69d21eb823b570fe5ee31e61 179 PRINTS PR01576 Peptide deformylase signature 102 113 2.8E-30 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS02235 052944bd69d21eb823b570fe5ee31e61 179 PRINTS PR01576 Peptide deformylase signature 114 132 2.8E-30 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS02235 052944bd69d21eb823b570fe5ee31e61 179 PRINTS PR01576 Peptide deformylase signature 43 72 2.8E-30 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS02235 052944bd69d21eb823b570fe5ee31e61 179 PRINTS PR01576 Peptide deformylase signature 133 162 2.8E-30 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS19715 bad59508d674e9235c3dcac855e04ec1 297 PIRSF PIRSF010376 1 296 1.5E-75 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 LK06_RS19715 bad59508d674e9235c3dcac855e04ec1 297 Pfam PF08544 GHMP kinases C terminal 203 276 1.8E-11 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain LK06_RS19715 bad59508d674e9235c3dcac855e04ec1 297 Pfam PF00288 GHMP kinases N terminal domain 87 145 1.1E-5 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 LK06_RS19715 bad59508d674e9235c3dcac855e04ec1 297 SUPERFAMILY SSF54211 2 157 4.71E-40 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS19715 bad59508d674e9235c3dcac855e04ec1 297 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 273 5.8E-50 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 LK06_RS19715 bad59508d674e9235c3dcac855e04ec1 297 Gene3D G3DSA:3.30.230.10 3 159 4.7E-47 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS19715 bad59508d674e9235c3dcac855e04ec1 297 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 289 29.78 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 LK06_RS19715 bad59508d674e9235c3dcac855e04ec1 297 Gene3D G3DSA:3.30.70.890 165 284 1.6E-26 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain LK06_RS19715 bad59508d674e9235c3dcac855e04ec1 297 SUPERFAMILY SSF55060 165 283 9.71E-23 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain LK06_RS21385 0cca6f613e578760d3c526177548c33d 119 SUPERFAMILY SSF103196 3 112 1.55E-18 T 06-07-2017 LK06_RS21385 0cca6f613e578760d3c526177548c33d 119 SMART SM00960 1 87 8.2E-11 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS21385 0cca6f613e578760d3c526177548c33d 119 Pfam PF03259 Roadblock/LC7 domain 4 86 1.2E-12 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS21385 0cca6f613e578760d3c526177548c33d 119 Gene3D G3DSA:3.30.450.30 2 112 2.2E-19 T 06-07-2017 LK06_RS04805 8d7469d24859d4622632342186b8c454 286 Gene3D G3DSA:3.40.1280.10 121 275 1.0E-47 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LK06_RS04805 8d7469d24859d4622632342186b8c454 286 Gene3D G3DSA:3.30.1330.30 8 109 2.8E-26 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like LK06_RS04805 8d7469d24859d4622632342186b8c454 286 Pfam PF00588 SpoU rRNA Methylase family 124 268 4.0E-36 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 LK06_RS04805 8d7469d24859d4622632342186b8c454 286 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 35 110 7.2E-9 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 LK06_RS04805 8d7469d24859d4622632342186b8c454 286 SMART SM00967 35 113 5.1E-9 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 LK06_RS04805 8d7469d24859d4622632342186b8c454 286 SUPERFAMILY SSF55315 8 110 3.3E-17 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like LK06_RS04805 8d7469d24859d4622632342186b8c454 286 SUPERFAMILY SSF75217 102 277 1.5E-40 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases LK06_RS26935 f01aa570a6652ab2b11e3c97242f531d 267 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS26935 f01aa570a6652ab2b11e3c97242f531d 267 SUPERFAMILY SSF52540 26 240 1.13E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26935 f01aa570a6652ab2b11e3c97242f531d 267 Pfam PF00005 ABC transporter 43 175 1.1E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS26935 f01aa570a6652ab2b11e3c97242f531d 267 Gene3D G3DSA:3.40.50.300 25 226 1.8E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26935 f01aa570a6652ab2b11e3c97242f531d 267 SMART SM00382 52 225 3.0E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 TIGRFAM TIGR01391 dnaG: DNA primase 5 421 4.7E-116 T 06-07-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 3.2E-35 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 Pfam PF10410 DnaB-helicase binding domain of primase 374 427 3.6E-15 T 06-07-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 Pfam PF13662 Toprim domain 263 333 5.5E-16 T 06-07-2017 IPR006171 Toprim domain LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 Gene3D G3DSA:3.90.980.10 117 242 1.4E-36 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 SUPERFAMILY SSF57783 4 102 1.36E-32 T 06-07-2017 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 SUPERFAMILY SSF56731 117 429 4.97E-92 T 06-07-2017 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 PIRSF PIRSF002811 2 626 7.4E-174 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 SMART SM00493 262 338 3.1E-16 T 06-07-2017 IPR006171 Toprim domain LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 Gene3D G3DSA:3.40.1360.10 244 370 5.9E-41 T 06-07-2017 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 Gene3D G3DSA:3.90.580.10 3 102 5.8E-37 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 Hamap MF_00974 DNA primase [dnaG]. 4 620 26.785 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 Pfam PF08278 DNA primase DnaG DnaB-binding 487 611 1.3E-14 T 06-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 Gene3D G3DSA:1.20.50.20 373 430 2.9E-9 T 06-07-2017 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 SMART SM00400 37 91 1.6E-33 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 Pfam PF01807 CHC2 zinc finger 6 101 1.2E-32 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 LK06_RS09180 b5a7e3ed19ae66ee1e220e7c242895cd 636 SMART SM00766 486 615 2.6E-21 T 06-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 LK06_RS16395 4be1573260ce9e4f048acb5b7bc2e27b 259 Gene3D G3DSA:1.10.10.10 9 77 1.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16395 4be1573260ce9e4f048acb5b7bc2e27b 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 3.9E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS16395 4be1573260ce9e4f048acb5b7bc2e27b 259 Pfam PF07702 UTRA domain 109 249 8.2E-28 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS16395 4be1573260ce9e4f048acb5b7bc2e27b 259 SMART SM00345 17 76 6.0E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS16395 4be1573260ce9e4f048acb5b7bc2e27b 259 SMART SM00866 108 250 2.0E-24 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS16395 4be1573260ce9e4f048acb5b7bc2e27b 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 4.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS16395 4be1573260ce9e4f048acb5b7bc2e27b 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 4.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS16395 4be1573260ce9e4f048acb5b7bc2e27b 259 SUPERFAMILY SSF46785 9 85 1.22E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16395 4be1573260ce9e4f048acb5b7bc2e27b 259 Gene3D G3DSA:3.40.1410.10 78 253 4.8E-53 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS16395 4be1573260ce9e4f048acb5b7bc2e27b 259 SUPERFAMILY SSF64288 64 255 1.57E-34 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS15830 2de375289eb13617d44dac886fa62000 689 SMART SM00387 61 205 6.3E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS15830 2de375289eb13617d44dac886fa62000 689 Gene3D G3DSA:3.40.50.670 454 671 1.2E-87 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR00418 DNA topoisomerase II family signature 143 157 2.0E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR00418 DNA topoisomerase II family signature 621 637 2.0E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR00418 DNA topoisomerase II family signature 574 586 2.0E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR00418 DNA topoisomerase II family signature 470 484 2.0E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR00418 DNA topoisomerase II family signature 536 552 2.0E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR00418 DNA topoisomerase II family signature 318 331 2.0E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR00418 DNA topoisomerase II family signature 65 80 2.0E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR00418 DNA topoisomerase II family signature 100 113 2.0E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR00418 DNA topoisomerase II family signature 554 571 2.0E-65 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 Gene3D G3DSA:3.30.230.10 267 442 3.9E-71 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS15830 2de375289eb13617d44dac886fa62000 689 SUPERFAMILY SSF54211 268 441 3.03E-55 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS15830 2de375289eb13617d44dac886fa62000 689 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 33 689 89.65 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 63 204 1.4E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS15830 2de375289eb13617d44dac886fa62000 689 SUPERFAMILY SSF56719 444 684 1.15E-82 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 36 689 6.3E-287 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 292 310 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 362 378 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 36 46 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 410 424 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 424 444 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 267 289 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 520 529 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 658 674 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 642 654 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 225 238 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 PRINTS PR01159 DNA gyrase subunit B signature 210 225 4.1E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 SUPERFAMILY SSF55874 36 241 5.12E-69 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS15830 2de375289eb13617d44dac886fa62000 689 ProSitePatterns PS00177 DNA topoisomerase II signature. 472 480 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 620 678 6.0E-25 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 Pfam PF01751 Toprim domain 469 579 6.3E-17 T 06-07-2017 IPR006171 Toprim domain LK06_RS15830 2de375289eb13617d44dac886fa62000 689 Pfam PF00204 DNA gyrase B 268 440 4.8E-62 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15830 2de375289eb13617d44dac886fa62000 689 Gene3D G3DSA:3.30.565.10 36 243 4.3E-87 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS15830 2de375289eb13617d44dac886fa62000 689 SMART SM00433 65 682 0.0 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS30205 8440240925953bab2e63ed560bafa32d 140 Pfam PF00011 Hsp20/alpha crystallin family 45 137 8.8E-19 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain LK06_RS30205 8440240925953bab2e63ed560bafa32d 140 SUPERFAMILY SSF49764 19 130 2.44E-26 T 06-07-2017 IPR008978 HSP20-like chaperone LK06_RS30205 8440240925953bab2e63ed560bafa32d 140 Gene3D G3DSA:2.60.40.790 37 137 3.0E-25 T 06-07-2017 IPR008978 HSP20-like chaperone LK06_RS21110 5e4587bec22cb8ec91883694e8dc5c5b 370 Pfam PF13796 Putative sensor 2 153 2.7E-21 T 06-07-2017 IPR025828 Putative sensor domain LK06_RS21110 5e4587bec22cb8ec91883694e8dc5c5b 370 Gene3D G3DSA:3.30.565.10 288 368 1.6E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21110 5e4587bec22cb8ec91883694e8dc5c5b 370 SUPERFAMILY SSF55874 256 368 4.45E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21110 5e4587bec22cb8ec91883694e8dc5c5b 370 Pfam PF07730 Histidine kinase 182 248 1.3E-9 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS06270 9713670f99b388c6323df38837ead8dc 272 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 9 255 2.3E-96 T 06-07-2017 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 LK06_RS06270 9713670f99b388c6323df38837ead8dc 272 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 215 1.9E-42 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06270 9713670f99b388c6323df38837ead8dc 272 Gene3D G3DSA:3.30.950.10 117 262 1.1E-34 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06270 9713670f99b388c6323df38837ead8dc 272 SUPERFAMILY SSF53790 3 255 1.3E-66 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06270 9713670f99b388c6323df38837ead8dc 272 Gene3D G3DSA:3.40.1010.10 6 116 1.8E-32 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS19085 32efbe1089abc2e133a91b3620c873fd 504 SUPERFAMILY SSF47413 7 71 6.29E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS19085 32efbe1089abc2e133a91b3620c873fd 504 Pfam PF13560 Helix-turn-helix domain 9 72 2.6E-10 T 06-07-2017 LK06_RS19085 32efbe1089abc2e133a91b3620c873fd 504 Gene3D G3DSA:1.10.260.40 6 71 6.8E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS24320 e32d37bd1d99c0e47cdad04e9e74dae8 404 SUPERFAMILY SSF55797 283 403 6.28E-25 T 06-07-2017 IPR014044 CAP domain LK06_RS24320 e32d37bd1d99c0e47cdad04e9e74dae8 404 Pfam PF00188 Cysteine-rich secretory protein family 288 402 2.2E-20 T 06-07-2017 IPR014044 CAP domain LK06_RS24320 e32d37bd1d99c0e47cdad04e9e74dae8 404 Gene3D G3DSA:3.40.33.10 280 396 5.9E-13 T 06-07-2017 IPR014044 CAP domain LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 Pfam PF13424 Tetratricopeptide repeat 468 536 5.3E-10 T 06-07-2017 LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 Gene3D G3DSA:1.25.40.10 465 547 8.6E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 Gene3D G3DSA:1.25.40.10 361 377 8.6E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 Pfam PF00931 NB-ARC domain 44 234 1.9E-9 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 SUPERFAMILY SSF48452 512 647 4.05E-16 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 SMART SM00382 52 207 3.8E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 Gene3D G3DSA:3.40.50.300 51 144 2.3E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 PRINTS PR00364 Disease resistance protein signature 216 230 1.0E-6 T 06-07-2017 LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 PRINTS PR00364 Disease resistance protein signature 55 70 1.0E-6 T 06-07-2017 LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 PRINTS PR00364 Disease resistance protein signature 131 145 1.0E-6 T 06-07-2017 LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 SUPERFAMILY SSF48452 460 537 4.17E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 Gene3D G3DSA:1.25.40.10 548 648 3.7E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05710 c10075e34a492c9deac53a0698821c25 685 SUPERFAMILY SSF52540 14 268 2.32E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28885 3e3a8c6125fed7e45938b4aa50acc629 378 SUPERFAMILY SSF55729 5 145 1.24E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS28885 3e3a8c6125fed7e45938b4aa50acc629 378 Pfam PF00583 Acetyltransferase (GNAT) family 57 132 2.1E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS28885 3e3a8c6125fed7e45938b4aa50acc629 378 Gene3D G3DSA:3.40.630.30 4 146 7.6E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS27195 663f75b1d80b7e42858cf903206fcb3a 559 Gene3D G3DSA:2.30.38.10 359 432 4.8E-11 T 06-07-2017 LK06_RS27195 663f75b1d80b7e42858cf903206fcb3a 559 Gene3D G3DSA:3.40.50.980 57 193 3.7E-17 T 06-07-2017 LK06_RS27195 663f75b1d80b7e42858cf903206fcb3a 559 Gene3D G3DSA:3.40.50.980 194 342 1.0E-13 T 06-07-2017 LK06_RS27195 663f75b1d80b7e42858cf903206fcb3a 559 Pfam PF00501 AMP-binding enzyme 56 437 2.5E-41 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS27195 663f75b1d80b7e42858cf903206fcb3a 559 SUPERFAMILY SSF56801 49 546 9.29E-67 T 06-07-2017 LK06_RS27195 663f75b1d80b7e42858cf903206fcb3a 559 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS27195 663f75b1d80b7e42858cf903206fcb3a 559 Gene3D G3DSA:3.30.300.30 450 539 7.1E-4 T 06-07-2017 LK06_RS28990 59a833c5a1f5e394eb7288faca7f13ae 295 Gene3D G3DSA:1.10.3720.10 10 282 1.5E-61 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS28990 59a833c5a1f5e394eb7288faca7f13ae 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 284 6.6E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS28990 59a833c5a1f5e394eb7288faca7f13ae 295 SUPERFAMILY SSF161098 15 295 2.15E-67 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS25210 84de9614f43430b7cb2722b4159326a6 177 Pfam PF02342 TerD domain 5 119 5.3E-13 T 06-07-2017 IPR003325 TerD domain GO:0006950 LK06_RS25210 84de9614f43430b7cb2722b4159326a6 177 Gene3D G3DSA:2.60.60.30 6 168 5.3E-34 T 06-07-2017 LK06_RS09210 f4d89728a141030200315e7d48205029 548 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 212 370 1.4E-51 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS09210 f4d89728a141030200315e7d48205029 548 Gene3D G3DSA:1.10.390.10 375 547 2.2E-56 T 06-07-2017 LK06_RS09210 f4d89728a141030200315e7d48205029 548 SUPERFAMILY SSF55486 211 547 6.78E-86 T 06-07-2017 LK06_RS09210 f4d89728a141030200315e7d48205029 548 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 373 547 3.3E-56 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 LK06_RS09210 f4d89728a141030200315e7d48205029 548 Gene3D G3DSA:3.10.170.10 211 373 5.6E-48 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS09210 f4d89728a141030200315e7d48205029 548 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 324 344 2.9E-20 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS09210 f4d89728a141030200315e7d48205029 548 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 361 377 2.9E-20 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS09210 f4d89728a141030200315e7d48205029 548 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 450 466 2.9E-20 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS09210 f4d89728a141030200315e7d48205029 548 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 382 393 2.9E-20 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS09210 f4d89728a141030200315e7d48205029 548 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 68 113 9.9E-14 T 06-07-2017 IPR011096 FTP domain LK06_RS01950 eff0f9955129ec9c12c21e983a116472 465 SUPERFAMILY SSF141571 249 285 1.18E-25 T 06-07-2017 LK06_RS01950 eff0f9955129ec9c12c21e983a116472 465 SUPERFAMILY SSF141571 364 462 1.18E-25 T 06-07-2017 LK06_RS01950 eff0f9955129ec9c12c21e983a116472 465 Pfam PF00805 Pentapeptide repeats (8 copies) 381 418 6.1E-12 T 06-07-2017 IPR001646 Pentapeptide repeat LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 SUPERFAMILY SSF143548 321 450 5.75E-34 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 Gene3D G3DSA:3.40.50.720 3 108 9.4E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 Gene3D G3DSA:3.30.70.260 447 524 3.6E-18 T 06-07-2017 LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 7 527 3.9E-188 T 06-07-2017 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 Pfam PF01842 ACT domain 455 514 4.0E-9 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 SUPERFAMILY SSF55021 455 526 1.79E-14 T 06-07-2017 LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 SUPERFAMILY SSF51735 103 282 1.23E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 Gene3D G3DSA:3.30.1330.90 319 446 3.4E-43 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 SUPERFAMILY SSF52283 4 136 2.27E-36 T 06-07-2017 LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 Gene3D G3DSA:3.40.50.720 109 284 1.1E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 314 1.4E-32 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 LK06_RS23970 f80b10340801198920b66adeeceb77d4 529 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 282 4.5E-63 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 Gene3D G3DSA:3.60.20.10 11 431 1.2E-184 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 SUPERFAMILY SSF56235 11 422 2.14E-146 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 SUPERFAMILY SSF69336 1212 1477 4.97E-87 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 Pfam PF01493 GXGXG motif 1248 1425 1.9E-76 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 Gene3D G3DSA:2.160.20.60 1217 1492 2.3E-103 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 Gene3D G3DSA:3.20.20.70 835 1194 6.1E-181 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 Pfam PF00310 Glutamine amidotransferases class-II 11 420 6.6E-180 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 SUPERFAMILY SSF51395 435 1199 1.55E-265 T 06-07-2017 LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 Pfam PF04898 Glutamate synthase central domain 447 735 5.2E-113 T 06-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 Pfam PF01645 Conserved region in glutamate synthase 800 1163 9.7E-158 T 06-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 LK06_RS07040 dca424e6c1ce1474cb178adb379fe400 1504 Gene3D G3DSA:3.20.20.70 432 787 2.4E-104 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS03715 80fd52e1e4565ba5c0b83844f397c8b9 178 Pfam PF00293 NUDIX domain 48 160 1.2E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS03715 80fd52e1e4565ba5c0b83844f397c8b9 178 SUPERFAMILY SSF55811 12 176 1.62E-23 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS03715 80fd52e1e4565ba5c0b83844f397c8b9 178 ProSitePatterns PS00893 Nudix box signature. 83 104 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS03715 80fd52e1e4565ba5c0b83844f397c8b9 178 Gene3D G3DSA:3.90.79.10 35 163 2.2E-16 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS21080 6c9af8fca2d94c6e8329c76f2d58c6ad 343 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 27 324 2.3E-34 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LK06_RS21080 6c9af8fca2d94c6e8329c76f2d58c6ad 343 SUPERFAMILY SSF51735 8 332 2.31E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS21080 6c9af8fca2d94c6e8329c76f2d58c6ad 343 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 9 334 7.6E-125 T 06-07-2017 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB LK06_RS21080 6c9af8fca2d94c6e8329c76f2d58c6ad 343 Gene3D G3DSA:3.30.1780.10 8 148 6.7E-41 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 LK06_RS21080 6c9af8fca2d94c6e8329c76f2d58c6ad 343 PIRSF PIRSF001439 2 334 3.2E-75 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LK06_RS21080 6c9af8fca2d94c6e8329c76f2d58c6ad 343 Gene3D G3DSA:3.40.50.720 149 303 8.9E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS19525 aa284c8ba55c979919f9b7c70e8168dc 577 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 373 485 4.4E-10 T 06-07-2017 IPR003390 DNA integrity scanning protein, DisA, N-terminal LK06_RS19525 aa284c8ba55c979919f9b7c70e8168dc 577 Gene3D G3DSA:3.40.1700.10 369 483 1.6E-6 T 06-07-2017 LK06_RS19525 aa284c8ba55c979919f9b7c70e8168dc 577 SUPERFAMILY SSF143597 366 485 4.97E-8 T 06-07-2017 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SUPERFAMILY SSF53901 187 418 4.76E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SUPERFAMILY SSF53901 450 471 4.76E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SUPERFAMILY SSF53901 6 128 4.76E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Gene3D G3DSA:3.40.366.10 762 873 1.0E-29 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Gene3D G3DSA:3.40.366.10 647 716 1.0E-29 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Gene3D G3DSA:3.40.47.10 8 304 8.5E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 205 221 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Gene3D G3DSA:3.90.470.20 1306 1399 1.0E-9 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Gene3D G3DSA:3.40.47.10 305 474 9.4E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 427 481 1.4E-8 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SUPERFAMILY SSF56214 1409 1494 2.62E-13 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 300 422 1.1E-33 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SUPERFAMILY SSF56214 1306 1399 5.62E-11 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 1409 1488 5.6E-10 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Gene3D G3DSA:3.90.470.20 1409 1485 3.4E-10 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Pfam PF00698 Acyl transferase domain 648 844 7.7E-17 T 06-07-2017 IPR014043 Acyl transferase LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 292 5.6E-60 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SUPERFAMILY SSF54637 1153 1257 1.77E-6 T 06-07-2017 IPR029069 HotDog domain LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 595 880 1.2E-14 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SUPERFAMILY SSF52151 591 692 3.66E-32 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SUPERFAMILY SSF52151 764 864 3.66E-32 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SUPERFAMILY SSF55048 700 761 2.49E-5 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 SMART SM00825 Beta-ketoacyl synthase 8 475 3.6E-95 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS03045 c4c73728d24bc80a68d071162fe533f9 1538 Pfam PF14765 Polyketide synthase dehydratase 1032 1270 1.1E-19 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS10735 11989751016c1d75a122a61069f2d514 349 SUPERFAMILY SSF53807 54 333 1.02E-28 T 06-07-2017 LK06_RS10735 11989751016c1d75a122a61069f2d514 349 Gene3D G3DSA:3.40.50.1980 199 325 8.1E-12 T 06-07-2017 LK06_RS10735 11989751016c1d75a122a61069f2d514 349 Pfam PF01497 Periplasmic binding protein 79 318 6.0E-16 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 LK06_RS10735 11989751016c1d75a122a61069f2d514 349 Gene3D G3DSA:3.40.50.1980 53 172 2.2E-10 T 06-07-2017 LK06_RS28770 f10f6669870fb030e0175e056a3bfd62 207 Gene3D G3DSA:2.60.120.10 87 188 3.2E-19 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS28770 f10f6669870fb030e0175e056a3bfd62 207 SUPERFAMILY SSF51182 84 188 2.19E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS28770 f10f6669870fb030e0175e056a3bfd62 207 Pfam PF13560 Helix-turn-helix domain 19 77 1.6E-16 T 06-07-2017 LK06_RS28770 f10f6669870fb030e0175e056a3bfd62 207 SUPERFAMILY SSF47413 17 81 1.58E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS28770 f10f6669870fb030e0175e056a3bfd62 207 Gene3D G3DSA:1.10.260.40 17 86 9.2E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS28770 f10f6669870fb030e0175e056a3bfd62 207 Pfam PF07883 Cupin domain 119 186 2.7E-13 T 06-07-2017 IPR013096 Cupin 2, conserved barrel LK06_RS28770 f10f6669870fb030e0175e056a3bfd62 207 SMART SM00530 22 77 2.3E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS18425 02e92261e756efde19eb343072372202 606 SUPERFAMILY SSF49478 500 572 7.45E-5 T 06-07-2017 LK06_RS18425 02e92261e756efde19eb343072372202 606 Pfam PF05738 Cna protein B-type domain 394 458 4.5E-6 T 06-07-2017 IPR008454 Collagen-binding surface protein Cna-like, B-type domain LK06_RS18425 02e92261e756efde19eb343072372202 606 Pfam PF05738 Cna protein B-type domain 508 575 4.6E-6 T 06-07-2017 IPR008454 Collagen-binding surface protein Cna-like, B-type domain LK06_RS18425 02e92261e756efde19eb343072372202 606 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 80 366 1.7E-47 T 06-07-2017 IPR026588 Choice-of-anchor A domain LK06_RS21920 69c8b3f5acaad1196dae8c30118c99ee 303 Pfam PF02585 GlcNAc-PI de-N-acetylase 23 170 2.0E-24 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 LK06_RS21920 69c8b3f5acaad1196dae8c30118c99ee 303 Gene3D G3DSA:3.40.50.10320 19 296 1.1E-83 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 LK06_RS21920 69c8b3f5acaad1196dae8c30118c99ee 303 SUPERFAMILY SSF102588 20 286 8.89E-67 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 LK06_RS21920 69c8b3f5acaad1196dae8c30118c99ee 303 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 23 293 8.0E-115 T 06-07-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 LK06_RS21920 69c8b3f5acaad1196dae8c30118c99ee 303 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 22 293 39.09 T 06-07-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Gene3D G3DSA:2.40.50.140 330 401 2.5E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 SUPERFAMILY SSF47781 414 507 7.78E-44 T 06-07-2017 IPR010994 RuvA domain 2-like LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 SUPERFAMILY SSF47781 538 630 7.78E-44 T 06-07-2017 IPR010994 RuvA domain 2-like LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 641 711 2.0E-14 T 06-07-2017 IPR001357 BRCT domain LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Gene3D G3DSA:1.10.150.20 447 503 1.1E-6 T 06-07-2017 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Gene3D G3DSA:3.30.470.30 130 263 3.9E-49 T 06-07-2017 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Gene3D G3DSA:3.40.50.10190 641 718 1.2E-24 T 06-07-2017 IPR001357 BRCT domain LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 PIRSF PIRSF001604 7 720 5.9E-244 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Gene3D G3DSA:1.10.287.610 11 77 1.4E-27 T 06-07-2017 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 23 503 1.7E-175 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 SMART SM00292 641 718 2.5E-12 T 06-07-2017 IPR001357 BRCT domain LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Gene3D G3DSA:1.10.150.20 551 631 1.3E-27 T 06-07-2017 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 418 446 1.2E-7 T 06-07-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 SUPERFAMILY SSF56091 14 326 4.32E-113 T 06-07-2017 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 SMART SM00532 15 460 2.5E-258 T 06-07-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 SUPERFAMILY SSF50249 328 411 1.2E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 15 329 4.2E-124 T 06-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Hamap MF_01588 DNA ligase [ligA]. 14 715 51.381 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Pfam PF12826 Helix-hairpin-helix motif 557 620 2.5E-21 T 06-07-2017 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 SUPERFAMILY SSF52113 640 718 6.54E-19 T 06-07-2017 IPR001357 BRCT domain LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 333 409 1.1E-28 T 06-07-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 126 155 - T 06-07-2017 IPR018239 NAD-dependent DNA ligase, active site LK06_RS23875 1d8c0e510bc2f8e4fc787101afe3df09 731 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 342 357 - T 06-07-2017 IPR033136 NAD-dependent DNA ligase, conserved site LK06_RS10065 6a7ccd95d4f5420e7bd2070ae2128183 736 Pfam PF02446 4-alpha-glucanotransferase 174 682 2.3E-112 T 06-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 LK06_RS10065 6a7ccd95d4f5420e7bd2070ae2128183 736 SUPERFAMILY SSF51445 627 704 6.25E-136 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS10065 6a7ccd95d4f5420e7bd2070ae2128183 736 SUPERFAMILY SSF51445 168 593 6.25E-136 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS10065 6a7ccd95d4f5420e7bd2070ae2128183 736 Gene3D G3DSA:3.20.20.80 631 686 1.4E-159 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS10065 6a7ccd95d4f5420e7bd2070ae2128183 736 Gene3D G3DSA:3.20.20.80 168 596 1.4E-159 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS10065 6a7ccd95d4f5420e7bd2070ae2128183 736 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 133 682 1.5E-87 T 06-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 LK06_RS10345 2ec282b20536ec701e79ee441b3d40d7 473 Pfam PF02397 Bacterial sugar transferase 287 468 6.5E-50 T 06-07-2017 IPR003362 Bacterial sugar transferase LK06_RS10345 2ec282b20536ec701e79ee441b3d40d7 473 Pfam PF13727 CoA-binding domain 96 227 8.1E-8 T 06-07-2017 LK06_RS10345 2ec282b20536ec701e79ee441b3d40d7 473 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 86 472 1.4E-97 T 06-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase LK06_RS13445 15e1f88bc356cae54dd53a246dcefe1e 259 TIGRFAM TIGR02952 Sig70_famx2: RNA polymerase sigma-70 factor, TIGR02952 family 85 254 1.7E-78 T 06-07-2017 IPR014298 RNA polymerase sigma-X type LK06_RS13445 15e1f88bc356cae54dd53a246dcefe1e 259 SUPERFAMILY SSF88659 184 254 2.24E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS13445 15e1f88bc356cae54dd53a246dcefe1e 259 Pfam PF08281 Sigma-70, region 4 199 250 1.7E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS13445 15e1f88bc356cae54dd53a246dcefe1e 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 95 252 1.1E-29 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS13445 15e1f88bc356cae54dd53a246dcefe1e 259 SUPERFAMILY SSF88946 78 186 7.26E-27 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS13445 15e1f88bc356cae54dd53a246dcefe1e 259 Gene3D G3DSA:1.10.10.10 193 255 9.2E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13445 15e1f88bc356cae54dd53a246dcefe1e 259 Pfam PF04542 Sigma-70 region 2 100 167 1.2E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS13445 15e1f88bc356cae54dd53a246dcefe1e 259 Gene3D G3DSA:1.10.1740.10 82 192 3.6E-29 T 06-07-2017 LK06_RS11180 07c93dece50e65c8b352e94bc3ce4360 762 SMART SM00382 566 749 1.6E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS11180 07c93dece50e65c8b352e94bc3ce4360 762 Gene3D G3DSA:3.40.50.300 541 731 7.0E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11180 07c93dece50e65c8b352e94bc3ce4360 762 SUPERFAMILY SSF90123 211 516 1.24E-49 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS11180 07c93dece50e65c8b352e94bc3ce4360 762 Gene3D G3DSA:3.90.70.10 65 190 2.0E-7 T 06-07-2017 LK06_RS11180 07c93dece50e65c8b352e94bc3ce4360 762 Gene3D G3DSA:1.20.1560.10 211 516 3.8E-49 T 06-07-2017 LK06_RS11180 07c93dece50e65c8b352e94bc3ce4360 762 Pfam PF03412 Peptidase C39 family 58 191 5.9E-17 T 06-07-2017 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 LK06_RS11180 07c93dece50e65c8b352e94bc3ce4360 762 SUPERFAMILY SSF52540 536 737 1.54E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11180 07c93dece50e65c8b352e94bc3ce4360 762 Pfam PF00664 ABC transporter transmembrane region 223 492 9.6E-35 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS11180 07c93dece50e65c8b352e94bc3ce4360 762 Pfam PF00005 ABC transporter 557 704 4.3E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS21445 22be26f6a6b0ea321aa0c21e428a7791 443 SUPERFAMILY SSF48452 100 206 1.78E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS21445 22be26f6a6b0ea321aa0c21e428a7791 443 Pfam PF03704 Bacterial transcriptional activator domain 101 199 2.0E-10 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS21445 22be26f6a6b0ea321aa0c21e428a7791 443 Gene3D G3DSA:1.10.10.10 1 68 2.3E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21445 22be26f6a6b0ea321aa0c21e428a7791 443 Pfam PF00486 Transcriptional regulatory protein, C terminal 3 78 4.9E-5 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS21445 22be26f6a6b0ea321aa0c21e428a7791 443 SUPERFAMILY SSF46894 1 78 3.68E-5 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS21445 22be26f6a6b0ea321aa0c21e428a7791 443 SMART SM01043 101 219 2.1E-9 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS15390 9acd24ca5eb30ce6dbd43c0e60937c0a 72 Gene3D G3DSA:1.10.10.10 2 63 1.2E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15390 9acd24ca5eb30ce6dbd43c0e60937c0a 72 SUPERFAMILY SSF46894 3 42 3.13E-5 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS31835 966a7fe954df9b8bce6ebaa322f721c1 290 SUPERFAMILY SSF46785 1 84 6.81E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31835 966a7fe954df9b8bce6ebaa322f721c1 290 Gene3D G3DSA:3.40.190.10 174 220 3.2E-4 T 06-07-2017 LK06_RS31835 966a7fe954df9b8bce6ebaa322f721c1 290 Pfam PF03466 LysR substrate binding domain 90 279 8.2E-24 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS31835 966a7fe954df9b8bce6ebaa322f721c1 290 Gene3D G3DSA:3.40.190.10 90 173 6.6E-15 T 06-07-2017 LK06_RS31835 966a7fe954df9b8bce6ebaa322f721c1 290 SUPERFAMILY SSF53850 90 283 2.82E-22 T 06-07-2017 LK06_RS31835 966a7fe954df9b8bce6ebaa322f721c1 290 Gene3D G3DSA:1.10.10.10 1 84 7.7E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31835 966a7fe954df9b8bce6ebaa322f721c1 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.8E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31835 966a7fe954df9b8bce6ebaa322f721c1 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.6E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31835 966a7fe954df9b8bce6ebaa322f721c1 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.6E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31835 966a7fe954df9b8bce6ebaa322f721c1 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.6E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 SMART SM00382 566 724 3.1E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 SMART SM00382 229 376 2.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 744 824 7.7E-24 T 06-07-2017 IPR019489 Clp ATPase, C-terminal LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Gene3D G3DSA:3.40.50.300 190 374 6.9E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 49 94 7.2E-7 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 126 169 2.9E-8 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Pfam PF07724 AAA domain (Cdc48 subfamily) 565 738 1.0E-52 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 SUPERFAMILY SSF52540 515 833 3.5E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 615 633 4.5E-41 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 691 4.5E-41 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 570 588 4.5E-41 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 644 662 4.5E-41 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 234 366 6.1E-11 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 SUPERFAMILY SSF52540 190 483 5.32E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Pfam PF02151 UvrB/uvrC motif 448 482 7.7E-9 T 06-07-2017 IPR001943 UVR domain GO:0005515 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 327 339 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Gene3D G3DSA:1.10.8.60 752 837 4.8E-29 T 06-07-2017 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 SMART SM01086 744 833 1.0E-34 T 06-07-2017 IPR019489 Clp ATPase, C-terminal LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Gene3D G3DSA:1.10.8.60 376 459 1.1E-33 T 06-07-2017 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 SUPERFAMILY SSF81923 37 105 6.87E-5 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Gene3D G3DSA:1.10.1780.10 38 165 2.6E-22 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 SUPERFAMILY SSF81923 115 203 1.44E-8 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Gene3D G3DSA:3.40.50.300 520 692 4.3E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 Gene3D G3DSA:3.40.50.300 727 751 4.3E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27820 a515d2ccd618bc241bb849a497d28a5d 845 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 600 618 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 LK06_RS32205 acdcdc43b7e355d2c42bda9682e7151c 420 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 74 131 1.1E-7 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS32205 acdcdc43b7e355d2c42bda9682e7151c 420 Gene3D G3DSA:1.10.150.130 74 200 6.3E-19 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS32205 acdcdc43b7e355d2c42bda9682e7151c 420 SUPERFAMILY SSF56349 74 398 1.18E-70 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS32205 acdcdc43b7e355d2c42bda9682e7151c 420 Gene3D G3DSA:1.10.443.10 205 398 1.1E-45 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS32205 acdcdc43b7e355d2c42bda9682e7151c 420 Pfam PF00589 Phage integrase family 206 389 2.0E-30 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS27765 a5fbe49ced1c8ae75dfbecc7807d3bf0 976 SUPERFAMILY SSF52540 7 96 8.76E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27765 a5fbe49ced1c8ae75dfbecc7807d3bf0 976 SUPERFAMILY SSF52540 142 257 8.76E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27765 a5fbe49ced1c8ae75dfbecc7807d3bf0 976 Gene3D G3DSA:3.40.50.300 8 68 1.4E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27765 a5fbe49ced1c8ae75dfbecc7807d3bf0 976 Gene3D G3DSA:3.40.50.300 119 199 1.4E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27765 a5fbe49ced1c8ae75dfbecc7807d3bf0 976 SUPERFAMILY SSF46894 906 967 2.58E-11 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS27765 a5fbe49ced1c8ae75dfbecc7807d3bf0 976 SMART SM00421 912 969 6.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27765 a5fbe49ced1c8ae75dfbecc7807d3bf0 976 Pfam PF13191 AAA ATPase domain 8 176 1.3E-22 T 06-07-2017 LK06_RS27765 a5fbe49ced1c8ae75dfbecc7807d3bf0 976 Pfam PF00196 Bacterial regulatory proteins, luxR family 915 962 2.8E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27765 a5fbe49ced1c8ae75dfbecc7807d3bf0 976 SUPERFAMILY SSF48452 405 532 6.9E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS27765 a5fbe49ced1c8ae75dfbecc7807d3bf0 976 Gene3D G3DSA:1.10.10.10 913 967 2.7E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04585 5b866149b4b4faff57744211c717f242 274 Gene3D G3DSA:3.40.190.10 36 165 1.1E-51 T 06-07-2017 LK06_RS04585 5b866149b4b4faff57744211c717f242 274 SUPERFAMILY SSF53850 37 274 7.91E-83 T 06-07-2017 LK06_RS04585 5b866149b4b4faff57744211c717f242 274 Pfam PF03180 NLPA lipoprotein 37 273 8.5E-96 T 06-07-2017 IPR004872 Lipoprotein NlpA family LK06_RS04585 5b866149b4b4faff57744211c717f242 274 PIRSF PIRSF002854 2 274 4.5E-109 T 06-07-2017 IPR004872 Lipoprotein NlpA family LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 SUPERFAMILY SSF46955 413 484 2.01E-15 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 SUPERFAMILY SSF56037 206 405 1.07E-65 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Pfam PF03484 tRNA synthetase B5 domain 415 480 5.0E-17 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Gene3D G3DSA:3.30.56.10 164 193 6.5E-18 T 06-07-2017 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Gene3D G3DSA:3.30.56.10 1 40 6.5E-18 T 06-07-2017 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 SUPERFAMILY SSF54991 737 833 1.22E-22 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 SUPERFAMILY SSF55681 476 592 3.78E-43 T 06-07-2017 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 SUPERFAMILY SSF55681 622 725 3.78E-43 T 06-07-2017 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Gene3D G3DSA:2.40.50.140 45 162 1.1E-38 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 SMART SM00874 413 480 1.3E-21 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Pfam PF03147 Ferredoxin-fold anticodon binding domain 739 833 1.8E-21 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Pfam PF01588 Putative tRNA binding domain 48 154 7.4E-20 T 06-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Pfam PF03483 B3/4 domain 221 397 5.1E-68 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Gene3D G3DSA:3.30.70.380 741 833 1.7E-26 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Gene3D G3DSA:3.50.40.10 209 406 1.8E-84 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Gene3D G3DSA:3.30.56.20 412 484 4.1E-22 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 SUPERFAMILY SSF50249 45 204 1.09E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 827 40.186 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 833 2.3E-189 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 SMART SM00896 739 833 6.6E-39 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 SMART SM00873 221 397 2.7E-83 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 LK06_RS04790 8f879c5adb63f5698ca564e0c88edea2 834 Gene3D G3DSA:3.30.930.10 497 726 2.8E-64 T 06-07-2017 LK06_RS00145 1b48dd86e145db321a474cfdf99eebfe 355 Gene3D G3DSA:3.90.180.10 1 173 7.0E-55 T 06-07-2017 IPR011032 GroES-like LK06_RS00145 1b48dd86e145db321a474cfdf99eebfe 355 SUPERFAMILY SSF51735 142 301 5.0E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00145 1b48dd86e145db321a474cfdf99eebfe 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 130 2.7E-29 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS00145 1b48dd86e145db321a474cfdf99eebfe 355 Pfam PF00107 Zinc-binding dehydrogenase 178 291 2.8E-24 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS00145 1b48dd86e145db321a474cfdf99eebfe 355 SMART SM00829 8 343 2.5E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS00145 1b48dd86e145db321a474cfdf99eebfe 355 SUPERFAMILY SSF50129 1 156 1.52E-54 T 06-07-2017 IPR011032 GroES-like LK06_RS00145 1b48dd86e145db321a474cfdf99eebfe 355 Gene3D G3DSA:3.40.50.720 174 287 4.8E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00145 1b48dd86e145db321a474cfdf99eebfe 355 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LK06_RS23365 5f6eca5b11b719bd2233b4eed8a936f4 282 SUPERFAMILY SSF51735 3 182 1.1E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23365 5f6eca5b11b719bd2233b4eed8a936f4 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 06-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS23365 5f6eca5b11b719bd2233b4eed8a936f4 282 Gene3D G3DSA:3.40.50.720 3 187 2.9E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23365 5f6eca5b11b719bd2233b4eed8a936f4 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 3.5E-70 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS23365 5f6eca5b11b719bd2233b4eed8a936f4 282 Gene3D G3DSA:1.10.1040.10 188 282 3.0E-29 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS23365 5f6eca5b11b719bd2233b4eed8a936f4 282 SUPERFAMILY SSF48179 186 282 9.35E-27 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS23365 5f6eca5b11b719bd2233b4eed8a936f4 282 PIRSF PIRSF000105 1 282 6.7E-92 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 LK06_RS23365 5f6eca5b11b719bd2233b4eed8a936f4 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 9.2E-30 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS19135 ae39bf0cc7a25459518d7acc50a26492 509 Gene3D G3DSA:1.10.510.10 77 256 1.9E-46 T 06-07-2017 LK06_RS19135 ae39bf0cc7a25459518d7acc50a26492 509 SUPERFAMILY SSF56112 8 263 5.26E-73 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS19135 ae39bf0cc7a25459518d7acc50a26492 509 SMART SM00220 11 260 1.8E-65 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS19135 ae39bf0cc7a25459518d7acc50a26492 509 Pfam PF00069 Protein kinase domain 11 255 1.4E-48 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS19135 ae39bf0cc7a25459518d7acc50a26492 509 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS19135 ae39bf0cc7a25459518d7acc50a26492 509 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS19135 ae39bf0cc7a25459518d7acc50a26492 509 Gene3D G3DSA:3.30.200.20 3 76 1.3E-27 T 06-07-2017 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 Gene3D G3DSA:1.10.10.10 263 326 2.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 Gene3D G3DSA:1.10.10.10 173 224 8.3E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 Pfam PF00140 Sigma-70 factor, region 1.2 34 67 1.8E-11 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 293 319 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 SUPERFAMILY SSF88946 34 170 4.97E-48 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 Pfam PF04545 Sigma-70, region 4 269 321 3.4E-14 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 SUPERFAMILY SSF88659 231 326 6.69E-23 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 96 321 4.5E-33 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 PRINTS PR00046 Major sigma-70 factor signature 293 308 4.8E-25 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 PRINTS PR00046 Major sigma-70 factor signature 148 156 4.8E-25 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 PRINTS PR00046 Major sigma-70 factor signature 272 284 4.8E-25 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 PRINTS PR00046 Major sigma-70 factor signature 308 319 4.8E-25 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 PRINTS PR00046 Major sigma-70 factor signature 124 137 4.8E-25 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 SUPERFAMILY SSF88659 173 246 5.23E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 Gene3D G3DSA:1.10.601.10 28 169 8.4E-56 T 06-07-2017 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 Pfam PF04539 Sigma-70 region 3 179 255 2.9E-24 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 124 137 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS19285 575f1eff083bba00e75a47ccecf4dc7a 332 Pfam PF04542 Sigma-70 region 2 100 170 1.6E-20 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS24685 7771470327087ebf7ac29ff273f60ac8 646 Gene3D G3DSA:1.10.540.10 32 170 9.0E-29 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS24685 7771470327087ebf7ac29ff273f60ac8 646 Gene3D G3DSA:2.40.110.10 171 268 1.7E-32 T 06-07-2017 LK06_RS24685 7771470327087ebf7ac29ff273f60ac8 646 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 62 167 3.1E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS24685 7771470327087ebf7ac29ff273f60ac8 646 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 280 438 5.8E-30 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS24685 7771470327087ebf7ac29ff273f60ac8 646 Gene3D G3DSA:1.20.140.10 269 442 2.4E-47 T 06-07-2017 LK06_RS24685 7771470327087ebf7ac29ff273f60ac8 646 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 172 268 5.6E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS24685 7771470327087ebf7ac29ff273f60ac8 646 SUPERFAMILY SSF56645 33 290 1.01E-59 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS24685 7771470327087ebf7ac29ff273f60ac8 646 SUPERFAMILY SSF47203 282 439 1.77E-34 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 Gene3D G3DSA:3.30.450.20 146 266 6.1E-27 T 06-07-2017 LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 SUPERFAMILY SSF141868 456 706 2.09E-81 T 06-07-2017 IPR001633 EAL domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 Gene3D G3DSA:3.20.20.450 453 707 6.0E-95 T 06-07-2017 IPR001633 EAL domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 SMART SM00052 449 703 2.3E-98 T 06-07-2017 IPR001633 EAL domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 Gene3D G3DSA:3.30.70.270 280 445 2.4E-53 T 06-07-2017 LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 SMART SM00086 226 268 7.0E-5 T 06-07-2017 IPR001610 PAC motif LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 Pfam PF13426 PAS domain 165 267 8.5E-12 T 06-07-2017 IPR000014 PAS domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 Pfam PF00990 Diguanylate cyclase, GGDEF domain 279 435 4.2E-42 T 06-07-2017 IPR000160 GGDEF domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 150 271 1.7E-24 T 06-07-2017 IPR000014 PAS domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 SMART SM00091 153 219 1.9E-10 T 06-07-2017 IPR000014 PAS domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 277 439 2.5E-33 T 06-07-2017 IPR000160 GGDEF domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 Pfam PF00563 EAL domain 456 698 6.6E-70 T 06-07-2017 IPR001633 EAL domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 SMART SM00267 268 439 2.2E-62 T 06-07-2017 IPR000160 GGDEF domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 SUPERFAMILY SSF55785 145 266 3.87E-25 T 06-07-2017 IPR000014 PAS domain LK06_RS01605 d1609ccc39ae2a583fb09dd6298f2a95 714 SUPERFAMILY SSF55073 284 441 2.12E-42 T 06-07-2017 IPR029787 Nucleotide cyclase LK06_RS17360 e562b026dfb5a7851ac4b4e2c22878a8 187 Pfam PF00857 Isochorismatase family 10 143 2.3E-31 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS17360 e562b026dfb5a7851ac4b4e2c22878a8 187 Gene3D G3DSA:3.40.50.850 6 159 4.5E-40 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS17360 e562b026dfb5a7851ac4b4e2c22878a8 187 SUPERFAMILY SSF52499 4 143 4.58E-42 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS29130 7dbc71be8afc3b698c8693e83299d62f 216 Pfam PF12028 Protein of unknown function (DUF3515) 66 203 1.3E-13 T 06-07-2017 IPR021903 Protein of unknown function DUF3515 LK06_RS05085 d376aa289bea7280220afd9e18e569b8 534 Gene3D G3DSA:3.10.105.10 288 500 2.0E-46 T 06-07-2017 LK06_RS05085 d376aa289bea7280220afd9e18e569b8 534 SUPERFAMILY SSF53850 47 519 5.11E-98 T 06-07-2017 LK06_RS05085 d376aa289bea7280220afd9e18e569b8 534 PIRSF PIRSF002741 3 527 1.0E-74 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LK06_RS05085 d376aa289bea7280220afd9e18e569b8 534 Gene3D G3DSA:3.90.76.10 50 205 6.8E-31 T 06-07-2017 LK06_RS05085 d376aa289bea7280220afd9e18e569b8 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 449 1.3E-73 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS16915 dbdad0222952c95fa57afa0f2809fa7c 75 Pfam PF05713 Bacterial mobilisation protein (MobC) 19 51 1.4E-6 T 06-07-2017 IPR008687 Bacterial mobilisation LK06_RS23605 58f9ad757a90f4cec9377943981682ec 142 Gene3D G3DSA:1.10.1660.10 1 54 4.0E-23 T 06-07-2017 LK06_RS23605 58f9ad757a90f4cec9377943981682ec 142 Pfam PF13411 MerR HTH family regulatory protein 1 61 1.2E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS23605 58f9ad757a90f4cec9377943981682ec 142 SMART SM00422 1 69 5.3E-24 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS23605 58f9ad757a90f4cec9377943981682ec 142 Gene3D G3DSA:1.10.1660.10 55 117 1.1E-9 T 06-07-2017 LK06_RS23605 58f9ad757a90f4cec9377943981682ec 142 SUPERFAMILY SSF46955 1 112 3.44E-27 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS23605 58f9ad757a90f4cec9377943981682ec 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.4E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS23605 58f9ad757a90f4cec9377943981682ec 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.4E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS23605 58f9ad757a90f4cec9377943981682ec 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.4E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 243 267 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 SUPERFAMILY SSF57716 220 268 1.43E-12 T 06-07-2017 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 Gene3D G3DSA:1.10.8.50 123 268 1.2E-43 T 06-07-2017 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 Pfam PF06827 Zinc finger found in FPG and IleRS 241 269 1.8E-7 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 205 7.1E-22 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 29 103 2.9E-9 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 Gene3D G3DSA:3.20.190.10 2 122 9.0E-16 T 06-07-2017 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 SUPERFAMILY SSF46946 121 205 9.68E-25 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 SMART SM01232 122 214 2.9E-34 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 SUPERFAMILY SSF81624 2 123 5.36E-23 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS09970 e008a0a14a0b855e3ae4c4dce04ee29b 269 SMART SM00898 2 108 1.8E-19 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS19885 4dd41725d511813069af78eeb0c94ce9 235 Pfam PF07510 Protein of unknown function (DUF1524) 75 209 1.7E-16 T 06-07-2017 IPR011089 Domain of unknown function DUF1524 LK06_RS17265 a87960235c2da8760e8a2158ba6c9332 377 Gene3D G3DSA:3.40.430.10 3 219 1.0E-56 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 LK06_RS17265 a87960235c2da8760e8a2158ba6c9332 377 SUPERFAMILY SSF53597 2 219 6.12E-46 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 LK06_RS17265 a87960235c2da8760e8a2158ba6c9332 377 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 232 333 1.5E-15 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 LK06_RS17265 a87960235c2da8760e8a2158ba6c9332 377 Pfam PF01872 RibD C-terminal domain 4 213 2.6E-42 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 LK06_RS17265 a87960235c2da8760e8a2158ba6c9332 377 SUPERFAMILY SSF53927 232 361 1.67E-26 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 LK06_RS17265 a87960235c2da8760e8a2158ba6c9332 377 Gene3D G3DSA:3.40.140.10 230 361 1.4E-21 T 06-07-2017 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 Gene3D G3DSA:1.10.10.10 161 219 1.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 2.0E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 2.0E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 2.0E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 SMART SM00421 159 216 1.5E-26 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 5.0E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 Gene3D G3DSA:3.40.50.2300 11 160 3.2E-36 T 06-07-2017 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 SUPERFAMILY SSF46894 147 219 1.02E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 Pfam PF00072 Response regulator receiver domain 15 126 1.5E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 SMART SM00448 13 126 7.4E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS11510 077bfc15d941dec926563701d706c1d1 232 SUPERFAMILY SSF52172 12 142 4.13E-30 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS04730 91a78c27b714547893ca1d2457f050a5 857 Pfam PF09586 Bacterial membrane protein YfhO 25 557 1.8E-71 T 06-07-2017 IPR018580 Uncharacterised protein family YfhO LK06_RS19750 f9248f25de0cc9a49d38a95cb43eaaf5 322 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 238 2.0E-58 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS19750 f9248f25de0cc9a49d38a95cb43eaaf5 322 SUPERFAMILY SSF51735 1 316 7.33E-90 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS19750 f9248f25de0cc9a49d38a95cb43eaaf5 322 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 316 4.9E-117 T 06-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 LK06_RS19750 f9248f25de0cc9a49d38a95cb43eaaf5 322 Gene3D G3DSA:3.90.25.10 168 316 3.1E-44 T 06-07-2017 LK06_RS19750 f9248f25de0cc9a49d38a95cb43eaaf5 322 Gene3D G3DSA:3.40.50.720 1 167 2.6E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15475 8fe170f3d6da53cc9502a167b80d07be 250 Gene3D G3DSA:3.40.1280.10 108 242 1.1E-26 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LK06_RS15475 8fe170f3d6da53cc9502a167b80d07be 250 Pfam PF00588 SpoU rRNA Methylase family 109 239 6.6E-24 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 LK06_RS15475 8fe170f3d6da53cc9502a167b80d07be 250 SUPERFAMILY SSF75217 94 242 1.64E-28 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 SMART SM00191 99 157 3.4E-6 T 06-07-2017 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 SMART SM00191 349 408 3.3E-7 T 06-07-2017 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 SMART SM00191 162 208 3.4 T 06-07-2017 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 SMART SM00191 29 87 0.032 T 06-07-2017 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 SMART SM00191 420 473 0.31 T 06-07-2017 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 SMART SM00191 273 338 51.0 T 06-07-2017 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 PRINTS PR01185 Integrin alpha subunit signature 96 116 2.4E-6 T 06-07-2017 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 PRINTS PR01185 Integrin alpha subunit signature 164 188 2.4E-6 T 06-07-2017 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 PRINTS PR01185 Integrin alpha subunit signature 224 245 2.4E-6 T 06-07-2017 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 111 185 1.2E-10 T 06-07-2017 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 SUPERFAMILY SSF69318 37 448 2.22E-65 T 06-07-2017 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 Pfam PF01839 FG-GAP repeat 40 71 2.5E-5 T 06-07-2017 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 Pfam PF01839 FG-GAP repeat 353 391 5.9E-7 T 06-07-2017 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 Gene3D G3DSA:2.130.10.130 348 486 2.8E-21 T 06-07-2017 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 Gene3D G3DSA:2.130.10.130 195 330 2.4E-13 T 06-07-2017 LK06_RS14775 f23af0213b5f6f9c35b34cae990245e4 493 Gene3D G3DSA:2.130.10.130 35 194 4.2E-29 T 06-07-2017 LK06_RS09745 2334c404bb555a917b17023b3c5deb1e 240 SUPERFAMILY SSF64288 64 230 3.93E-20 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS09745 2334c404bb555a917b17023b3c5deb1e 240 Gene3D G3DSA:1.10.10.10 9 70 2.7E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09745 2334c404bb555a917b17023b3c5deb1e 240 SMART SM00345 10 68 7.7E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS09745 2334c404bb555a917b17023b3c5deb1e 240 SMART SM00866 93 233 4.2E-5 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS09745 2334c404bb555a917b17023b3c5deb1e 240 Gene3D G3DSA:3.40.1410.10 71 226 7.2E-22 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS09745 2334c404bb555a917b17023b3c5deb1e 240 Pfam PF07702 UTRA domain 97 225 1.2E-13 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS09745 2334c404bb555a917b17023b3c5deb1e 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 67 6.5E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS09745 2334c404bb555a917b17023b3c5deb1e 240 SUPERFAMILY SSF46785 5 82 2.56E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02215 e628ad1cc3f3002b8465d3bac0fa297f 173 Gene3D G3DSA:2.60.120.10 27 144 2.1E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS02215 e628ad1cc3f3002b8465d3bac0fa297f 173 SUPERFAMILY SSF51182 33 140 1.65E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS02215 e628ad1cc3f3002b8465d3bac0fa297f 173 Pfam PF00190 Cupin 15 135 1.4E-17 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 LK06_RS30480 6473b3e6ca3c9f37bea07547c0fe09f0 202 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 8 193 1.1E-68 T 06-07-2017 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 LK06_RS30480 6473b3e6ca3c9f37bea07547c0fe09f0 202 Pfam PF02734 DAK2 domain 31 193 6.5E-49 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 LK06_RS30480 6473b3e6ca3c9f37bea07547c0fe09f0 202 SUPERFAMILY SSF101473 2 195 1.44E-53 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 LK06_RS30480 6473b3e6ca3c9f37bea07547c0fe09f0 202 SMART SM01120 31 195 4.6E-71 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 428 472 5.8E-5 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 98 129 0.1 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 487 504 0.38 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 321 331 130.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 520 536 12.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 285 299 120.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 365 395 0.0066 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 238 267 7.4 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 162 203 0.0044 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 351 363 22.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Pfam PF08238 Sel1 repeat 148 160 28.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SUPERFAMILY SSF81901 147 272 2.04E-17 T 06-07-2017 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SUPERFAMILY SSF81901 26 131 9.15E-16 T 06-07-2017 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 236 267 3.3 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 300 331 170.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 66 97 53.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 130 160 16.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 268 299 17.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 428 472 210.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 332 363 14.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 34 65 110.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 473 504 8.9 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 204 235 100.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 161 203 12.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 537 568 66.0 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 505 536 6.6 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 98 129 0.016 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00671 364 395 0.076 T 06-07-2017 IPR006597 Sel1-like repeat LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Gene3D G3DSA:1.25.40.10 189 363 4.0E-39 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Gene3D G3DSA:1.25.40.10 364 583 1.4E-40 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 Gene3D G3DSA:1.25.40.10 27 173 6.4E-24 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SUPERFAMILY SSF81901 242 436 4.6E-29 T 06-07-2017 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00028 473 506 260.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00028 364 397 190.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00028 537 570 64.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00028 268 301 28.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SMART SM00028 34 67 90.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS22320 b824f82cd512f969314afa7e8cae037e 588 SUPERFAMILY SSF81901 456 570 4.45E-21 T 06-07-2017 LK06_RS17925 e29c00208023bfb32dca51dba781e31a 60 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 53 3.5E-11 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 LK06_RS17925 e29c00208023bfb32dca51dba781e31a 60 Pfam PF12728 Helix-turn-helix domain 6 53 1.2E-13 T 06-07-2017 LK06_RS15340 4ec55dd54a34e72d3ce3f9568fa28e89 271 Pfam PF00795 Carbon-nitrogen hydrolase 14 253 1.4E-50 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS15340 4ec55dd54a34e72d3ce3f9568fa28e89 271 Gene3D G3DSA:3.60.110.10 1 262 2.2E-81 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS15340 4ec55dd54a34e72d3ce3f9568fa28e89 271 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 149 169 - T 06-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site LK06_RS15340 4ec55dd54a34e72d3ce3f9568fa28e89 271 SUPERFAMILY SSF56317 1 262 4.32E-74 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 Gene3D G3DSA:3.40.50.1820 11 306 1.1E-70 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 PRINTS PR00412 Epoxide hydrolase signature 111 124 5.1E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 PRINTS PR00412 Epoxide hydrolase signature 281 303 5.1E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 PRINTS PR00412 Epoxide hydrolase signature 67 82 5.1E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 PRINTS PR00412 Epoxide hydrolase signature 47 65 5.1E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 PRINTS PR00412 Epoxide hydrolase signature 125 138 5.1E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 PRINTS PR00412 Epoxide hydrolase signature 247 263 5.1E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 5.1E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 5.1E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 5.1E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 Pfam PF12697 Alpha/beta hydrolase family 43 295 8.7E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS14105 49deb05e1cf0c54c5c85ab893b900d15 311 SUPERFAMILY SSF53474 18 306 1.7E-66 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS01180 e1d4855affde93d6edf231e0bbd014c8 147 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 36 144 7.6E-36 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 LK06_RS01180 e1d4855affde93d6edf231e0bbd014c8 147 Pfam PF04075 Domain of unknown function (DUF385) 14 144 6.6E-52 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 LK06_RS19790 610d60cb997d716eec759f1a29b23530 274 SUPERFAMILY SSF53335 6 222 2.28E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19790 610d60cb997d716eec759f1a29b23530 274 Gene3D G3DSA:1.10.150.290 197 254 2.2E-26 T 06-07-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 LK06_RS19790 610d60cb997d716eec759f1a29b23530 274 Pfam PF13649 Methyltransferase domain 43 139 3.7E-15 T 06-07-2017 LK06_RS19790 610d60cb997d716eec759f1a29b23530 274 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 4 273 42.626 T 06-07-2017 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 LK06_RS19790 610d60cb997d716eec759f1a29b23530 274 Gene3D G3DSA:3.40.50.150 6 195 1.6E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS29610 c85493880226434c08e1172aa869f9c3 402 Gene3D G3DSA:3.30.420.40 235 365 3.4E-44 T 06-07-2017 LK06_RS29610 c85493880226434c08e1172aa869f9c3 402 Pfam PF00480 ROK family 99 385 7.7E-48 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS29610 c85493880226434c08e1172aa869f9c3 402 Gene3D G3DSA:1.10.10.10 24 91 1.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29610 c85493880226434c08e1172aa869f9c3 402 SUPERFAMILY SSF46785 24 86 1.86E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29610 c85493880226434c08e1172aa869f9c3 402 SUPERFAMILY SSF53067 99 390 2.27E-42 T 06-07-2017 LK06_RS29610 c85493880226434c08e1172aa869f9c3 402 Gene3D G3DSA:3.30.420.40 98 234 1.3E-30 T 06-07-2017 LK06_RS00400 860d3722da49e8e21c54ba6fc667c7d5 304 Gene3D G3DSA:3.20.20.380 7 254 1.1E-67 T 06-07-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 LK06_RS00400 860d3722da49e8e21c54ba6fc667c7d5 304 SUPERFAMILY SSF110395 7 216 4.45E-50 T 06-07-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 LK06_RS00400 860d3722da49e8e21c54ba6fc667c7d5 304 Pfam PF03932 CutC family 8 211 6.5E-53 T 06-07-2017 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 LK06_RS32150 62b8ffcbd322f54889f0ca77a0fe7cad 373 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 363 48.3 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LK06_RS32150 62b8ffcbd322f54889f0ca77a0fe7cad 373 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 360 1.6E-87 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LK06_RS32150 62b8ffcbd322f54889f0ca77a0fe7cad 373 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 226 235 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 LK06_RS32150 62b8ffcbd322f54889f0ca77a0fe7cad 373 SUPERFAMILY SSF53383 25 360 1.39E-73 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS32150 62b8ffcbd322f54889f0ca77a0fe7cad 373 Gene3D G3DSA:3.40.640.10 40 252 6.0E-47 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS32150 62b8ffcbd322f54889f0ca77a0fe7cad 373 Gene3D G3DSA:3.90.1150.10 253 361 8.0E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS32150 62b8ffcbd322f54889f0ca77a0fe7cad 373 Pfam PF00155 Aminotransferase class I and II 28 357 3.2E-58 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 Pfam PF02503 Polyphosphate kinase middle domain 197 387 6.3E-66 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 PIRSF PIRSF015589 65 763 1.0E-284 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 81 752 7.3E-252 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 Hamap MF_00347 Polyphosphate kinase [ppk]. 79 755 34.169 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 SUPERFAMILY SSF56024 574 755 2.02E-66 T 06-07-2017 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 Pfam PF13089 Polyphosphate kinase N-terminal domain 82 188 3.6E-37 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 SUPERFAMILY SSF56024 399 571 4.71E-56 T 06-07-2017 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 Gene3D G3DSA:3.30.870.10 574 756 2.9E-71 T 06-07-2017 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 Pfam PF13090 Polyphosphate kinase C-terminal domain 403 751 4.7E-154 T 06-07-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 Gene3D G3DSA:3.30.1840.10 184 369 1.1E-72 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 Gene3D G3DSA:3.30.870.10 398 573 1.3E-78 T 06-07-2017 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 SUPERFAMILY SSF140356 79 183 2.49E-36 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 LK06_RS17550 92254ad6122baeeaf38def0c97d75336 764 SUPERFAMILY SSF143724 185 381 1.79E-64 T 06-07-2017 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 Gene3D G3DSA:3.40.47.10 280 397 4.8E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 Gene3D G3DSA:3.40.47.10 152 191 4.8E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 Pfam PF02803 Thiolase, C-terminal domain 275 396 4.0E-37 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 Gene3D G3DSA:3.40.47.10 192 278 1.1E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 Gene3D G3DSA:3.40.47.10 7 131 1.1E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 PIRSF PIRSF000429 3 399 1.0E-121 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 Pfam PF00108 Thiolase, N-terminal domain 8 266 3.2E-57 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 SUPERFAMILY SSF53901 277 396 1.66E-37 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 396 4.2E-133 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 SUPERFAMILY SSF53901 7 273 5.59E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS26600 7167da8e0e4be749e7ff28f56a1087aa 404 ProSitePatterns PS00737 Thiolases signature 2. 343 359 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 2.9E-68 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 PIRSF PIRSF002133 1 123 8.4E-55 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 Gene3D G3DSA:2.40.50.140 2 123 3.3E-65 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 Pfam PF00164 Ribosomal protein S12/S23 3 123 1.5E-44 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 SUPERFAMILY SSF50249 2 123 6.77E-53 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS12415 a0e41c2799cf2c613b8f5763b914b45c 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.977 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS18695 d09f8db05f8ebd6c57a3ba5b4f858425 228 SUPERFAMILY SSF50475 23 228 2.14E-66 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS18695 d09f8db05f8ebd6c57a3ba5b4f858425 228 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 15 228 4.7E-80 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS18695 d09f8db05f8ebd6c57a3ba5b4f858425 228 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 187 228 1.8E-19 T 06-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS18695 d09f8db05f8ebd6c57a3ba5b4f858425 228 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 52 131 2.5E-23 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS18695 d09f8db05f8ebd6c57a3ba5b4f858425 228 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 20 228 39.507 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS18695 d09f8db05f8ebd6c57a3ba5b4f858425 228 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 197 210 - T 06-07-2017 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS18695 d09f8db05f8ebd6c57a3ba5b4f858425 228 Gene3D G3DSA:2.30.110.10 26 228 3.6E-83 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS18695 d09f8db05f8ebd6c57a3ba5b4f858425 228 PIRSF PIRSF000190 9 228 8.2E-83 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 Pfam PF08448 PAS fold 222 317 5.3E-5 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 Gene3D G3DSA:3.30.565.10 386 536 1.6E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 SUPERFAMILY SSF55785 209 315 3.72E-8 T 06-07-2017 IPR000014 PAS domain LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 Gene3D G3DSA:1.10.287.130 313 369 1.2E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 SUPERFAMILY SSF55874 395 534 1.31E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 Gene3D G3DSA:3.30.450.20 36 173 3.1E-43 T 06-07-2017 LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 SUPERFAMILY SSF103190 42 172 2.98E-33 T 06-07-2017 IPR029151 Periplasmic sensor domain-like LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 Pfam PF17203 Single cache domain 3 40 173 2.0E-30 T 06-07-2017 IPR033463 Single cache domain 3 LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 425 535 1.3E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 SMART SM00387 422 536 7.8E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 511 3.8E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 489 3.8E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 475 3.8E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 533 3.8E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS23575 12886eb2fef1666cfee7ce53b873f53a 546 Gene3D G3DSA:3.30.450.20 212 312 4.8E-11 T 06-07-2017 LK06_RS19760 9f10676c36d977154a3e6f77dfc29fd0 150 Gene3D G3DSA:1.10.287.1060 76 137 1.4E-4 T 06-07-2017 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2052 2167 1.8E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 1.8E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF51735 3149 3392 3.28E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.366.10 761 863 1.9E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.366.10 2515 2624 9.9E-78 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.366.10 2313 2441 9.9E-78 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.366.10 562 694 1.9E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00825 Beta-ketoacyl synthase 1795 2220 7.0E-217 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00825 Beta-ketoacyl synthase 36 461 1.4E-227 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.30.70.250 700 760 5.5E-7 T 06-07-2017 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00824 Thioesterase 3583 3792 5.1E-55 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 534 1.9E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2170 2285 2.2E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 571 871 2.5E-108 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2322 2625 1.3E-110 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF52151 2508 2607 9.68E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF52151 2319 2441 9.68E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF47336 1694 1808 1.31E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.50.720 1412 1595 3.8E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.50.720 3152 3336 3.2E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.50.720 3433 3441 3.2E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF14765 Polyketide synthase dehydratase 939 1221 1.2E-50 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF14765 Polyketide synthase dehydratase 2690 2963 4.6E-49 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.50.1820 3527 3795 1.9E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1957 1973 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF00975 Thioesterase domain 3582 3687 7.1E-16 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF47336 3435 3537 3.8E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF52151 762 855 1.26E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF52151 568 700 1.26E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.47.10 30 295 2.2E-94 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.47.10 1790 2056 5.5E-93 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF55048 2445 2515 1.83E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00826 2690 2849 3.5E-67 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00826 939 1108 1.5E-63 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF00550 Phosphopantetheine attachment site 1697 1764 1.4E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF00550 Phosphopantetheine attachment site 3439 3505 2.0E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:1.10.1200.10 1695 1768 1.3E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:1.10.1200.10 3442 3510 1.8E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.47.10 296 461 6.1E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.40.47.10 2057 2220 1.5E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF53901 31 406 3.49E-104 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF00698 Acyl transferase domain 570 890 2.0E-59 T 06-07-2017 IPR014043 Acyl transferase LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF00698 Acyl transferase domain 2321 2642 1.3E-56 T 06-07-2017 IPR014043 Acyl transferase LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF53901 1789 2159 9.48E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF53474 3467 3505 1.52E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF53474 3558 3793 1.52E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF08659 KR domain 3154 3332 3.0E-58 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF08659 KR domain 1413 1591 1.8E-58 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF08990 Erythronolide synthase docking 3 27 2.9E-10 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Gene3D G3DSA:3.30.70.250 2445 2514 1.4E-5 T 06-07-2017 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM01294 1697 1764 7.7E-6 T 06-07-2017 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM01294 3438 3505 1.0E-4 T 06-07-2017 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF51735 1227 1400 2.56E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF55048 699 761 7.72E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00823 Phosphopantetheine attachment site 1696 1768 7.7E-29 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00823 Phosphopantetheine attachment site 3437 3509 1.1E-27 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3154 3334 6.6E-52 T 06-07-2017 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1413 1593 2.7E-52 T 06-07-2017 LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF51735 2971 3141 2.87E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 283 1.2E-92 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1793 2044 4.3E-90 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS25675 fbc6c86772af074dda160aaf11806f6d 3798 SUPERFAMILY SSF51735 1410 1657 2.7E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 SMART SM00382 18 190 4.8E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 SUPERFAMILY SSF48452 602 740 9.86E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 SMART SM00421 871 928 3.5E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 SUPERFAMILY SSF46894 863 930 2.72E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 SUPERFAMILY SSF52540 2 207 3.63E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 Gene3D G3DSA:1.25.40.10 471 646 8.0E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 Gene3D G3DSA:1.25.40.10 647 817 3.0E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 Gene3D G3DSA:1.25.40.10 409 436 8.0E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 Pfam PF00196 Bacterial regulatory proteins, luxR family 873 928 1.4E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 Pfam PF13191 AAA ATPase domain 16 156 1.6E-19 T 06-07-2017 LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 Gene3D G3DSA:1.10.10.10 865 929 8.1E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 Gene3D G3DSA:3.40.50.300 3 176 5.4E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 904 916 3.1E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 888 904 3.1E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27330 7ecc554753e2fd8a3fce1c658008146e 934 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 874 888 3.1E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS03005 bd7abd9921058c25b353935f891741e8 254 Gene3D G3DSA:2.160.10.10 64 210 3.9E-38 T 06-07-2017 LK06_RS03005 bd7abd9921058c25b353935f891741e8 254 SUPERFAMILY SSF51161 54 209 3.14E-35 T 06-07-2017 IPR011004 Trimeric LpxA-like LK06_RS03005 bd7abd9921058c25b353935f891741e8 254 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 161 189 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 LK06_RS03005 bd7abd9921058c25b353935f891741e8 254 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 153 187 1.0E-10 T 06-07-2017 IPR001451 Hexapeptide repeat LK06_RS03005 bd7abd9921058c25b353935f891741e8 254 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 96 130 0.0023 T 06-07-2017 IPR001451 Hexapeptide repeat LK06_RS01410 ca768d5ec6e0b9edd113e9799b9930b3 293 Gene3D G3DSA:3.40.630.30 18 107 3.3E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS01410 ca768d5ec6e0b9edd113e9799b9930b3 293 SUPERFAMILY SSF55729 96 287 1.26E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS01410 ca768d5ec6e0b9edd113e9799b9930b3 293 SUPERFAMILY SSF55729 18 110 4.29E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS01410 ca768d5ec6e0b9edd113e9799b9930b3 293 Gene3D G3DSA:3.40.630.30 165 289 7.4E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS01410 ca768d5ec6e0b9edd113e9799b9930b3 293 Pfam PF00583 Acetyltransferase (GNAT) family 29 104 1.9E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS01410 ca768d5ec6e0b9edd113e9799b9930b3 293 Pfam PF00583 Acetyltransferase (GNAT) family 202 276 7.0E-5 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 Pfam PF00106 short chain dehydrogenase 7 198 1.0E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.1E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.1E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.1E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.1E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.1E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 Gene3D G3DSA:3.40.50.720 5 240 8.2E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08330 6e9e09f6b327d1f78e8d8daa322be323 252 SUPERFAMILY SSF51735 1 232 4.2E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27290 1539b90d26845b9b3932e8908717ba2a 243 Gene3D G3DSA:3.20.20.60 6 224 3.0E-56 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS27290 1539b90d26845b9b3932e8908717ba2a 243 SUPERFAMILY SSF51621 7 242 1.21E-53 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS27290 1539b90d26845b9b3932e8908717ba2a 243 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 241 3.5E-61 T 06-07-2017 LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 419 580 1.8E-47 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 SUPERFAMILY SSF52467 212 387 7.89E-62 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 456 475 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 355 1.8E-46 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 31 604 1.7E-230 T 06-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 Gene3D G3DSA:3.40.50.970 382 596 3.7E-76 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 31 196 9.8E-55 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 SUPERFAMILY SSF52518 396 610 9.11E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 SUPERFAMILY SSF52518 29 210 5.47E-59 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 Gene3D G3DSA:3.40.50.970 29 206 1.6E-70 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS23955 315bad4fec329b889ba833e5360f0fa3 618 Gene3D G3DSA:3.40.50.1220 213 381 1.8E-66 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS09650 d6ed045ae3be6d4292ae625b685d1874 428 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 334 355 - T 06-07-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LK06_RS09650 d6ed045ae3be6d4292ae625b685d1874 428 SUPERFAMILY SSF53720 10 427 1.31E-118 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS09650 d6ed045ae3be6d4292ae625b685d1874 428 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 12 427 42.298 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LK06_RS09650 d6ed045ae3be6d4292ae625b685d1874 428 PIRSF PIRSF000151 6 428 8.0E-177 T 06-07-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 LK06_RS09650 d6ed045ae3be6d4292ae625b685d1874 428 Pfam PF00171 Aldehyde dehydrogenase family 12 299 7.4E-22 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS09650 d6ed045ae3be6d4292ae625b685d1874 428 Gene3D G3DSA:3.40.309.10 234 385 1.0E-41 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS09650 d6ed045ae3be6d4292ae625b685d1874 428 Gene3D G3DSA:3.40.605.10 8 231 8.3E-105 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS09650 d6ed045ae3be6d4292ae625b685d1874 428 Gene3D G3DSA:3.40.605.10 386 427 8.3E-105 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS09650 d6ed045ae3be6d4292ae625b685d1874 428 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 20 417 1.2E-155 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LK06_RS06295 e2f78ce22383484e924f34e68b56dbc0 366 Pfam PF00155 Aminotransferase class I and II 41 357 2.2E-30 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS06295 e2f78ce22383484e924f34e68b56dbc0 366 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 218 231 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 LK06_RS06295 e2f78ce22383484e924f34e68b56dbc0 366 SUPERFAMILY SSF53383 34 353 1.08E-57 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS06295 e2f78ce22383484e924f34e68b56dbc0 366 Gene3D G3DSA:3.40.640.10 52 260 4.0E-50 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS06295 e2f78ce22383484e924f34e68b56dbc0 366 Gene3D G3DSA:3.90.1150.10 261 364 1.6E-14 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS01455 bc8a9fec68864024e991bdeb9007794e 247 SUPERFAMILY SSF52540 22 243 7.38E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01455 bc8a9fec68864024e991bdeb9007794e 247 Pfam PF00005 ABC transporter 39 183 3.2E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS01455 bc8a9fec68864024e991bdeb9007794e 247 Gene3D G3DSA:3.40.50.300 22 243 4.3E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01455 bc8a9fec68864024e991bdeb9007794e 247 SMART SM00382 48 231 1.6E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS05090 e344ce10125c7e6441444049fcc7d7fa 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 148 4.2E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS05090 e344ce10125c7e6441444049fcc7d7fa 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 170 4.2E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS05090 e344ce10125c7e6441444049fcc7d7fa 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 4.2E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS05090 e344ce10125c7e6441444049fcc7d7fa 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 4.2E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS05090 e344ce10125c7e6441444049fcc7d7fa 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 188 3.8E-24 T 06-07-2017 IPR023214 HAD-like domain LK06_RS05090 e344ce10125c7e6441444049fcc7d7fa 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 82 188 7.1E-15 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS05090 e344ce10125c7e6441444049fcc7d7fa 222 SUPERFAMILY SSF56784 8 193 6.78E-46 T 06-07-2017 IPR023214 HAD-like domain LK06_RS05090 e344ce10125c7e6441444049fcc7d7fa 222 Gene3D G3DSA:3.40.50.1000 6 21 9.2E-41 T 06-07-2017 IPR023214 HAD-like domain LK06_RS05090 e344ce10125c7e6441444049fcc7d7fa 222 Gene3D G3DSA:3.40.50.1000 93 209 9.2E-41 T 06-07-2017 IPR023214 HAD-like domain LK06_RS07410 88e1f852bd0e01209eef42f19b83fa74 215 Gene3D G3DSA:3.20.20.70 6 214 1.2E-71 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS07410 88e1f852bd0e01209eef42f19b83fa74 215 Pfam PF02581 Thiamine monophosphate synthase/TENI 14 195 1.6E-50 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LK06_RS07410 88e1f852bd0e01209eef42f19b83fa74 215 SUPERFAMILY SSF51391 8 212 3.14E-60 T 06-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LK06_RS07410 88e1f852bd0e01209eef42f19b83fa74 215 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 11 213 23.884 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LK06_RS07410 88e1f852bd0e01209eef42f19b83fa74 215 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 13 207 2.3E-58 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LK06_RS10295 ac6dd608d60c7964b3a0e8b25a15bcc9 288 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 219 230 - T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS10295 ac6dd608d60c7964b3a0e8b25a15bcc9 288 Pfam PF00264 Common central domain of tyrosinase 30 238 7.2E-41 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS10295 ac6dd608d60c7964b3a0e8b25a15bcc9 288 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 55 72 - T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS10295 ac6dd608d60c7964b3a0e8b25a15bcc9 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 55 72 7.6E-17 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS10295 ac6dd608d60c7964b3a0e8b25a15bcc9 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 218 236 7.6E-17 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS10295 ac6dd608d60c7964b3a0e8b25a15bcc9 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 199 210 7.6E-17 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS10295 ac6dd608d60c7964b3a0e8b25a15bcc9 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 84 89 7.6E-17 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS10295 ac6dd608d60c7964b3a0e8b25a15bcc9 288 Gene3D G3DSA:1.10.1280.10 3 268 1.8E-54 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre LK06_RS10295 ac6dd608d60c7964b3a0e8b25a15bcc9 288 SUPERFAMILY SSF48056 3 287 7.52E-56 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 141 183 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 Gene3D G3DSA:3.30.310.20 208 323 7.0E-33 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 SMART SM00342 104 187 1.0E-16 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 Pfam PF06029 AlkA N-terminal domain 209 323 9.7E-30 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 SUPERFAMILY SSF57884 4 86 5.49E-31 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 SMART SM00478 333 490 2.7E-29 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 SUPERFAMILY SSF55945 209 304 3.45E-25 T 06-07-2017 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 Pfam PF02805 Metal binding domain of Ada 12 75 3.1E-27 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 Pfam PF12833 Helix-turn-helix domain 110 189 1.5E-16 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 SUPERFAMILY SSF46689 141 191 1.61E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 Gene3D G3DSA:3.40.10.10 5 86 8.5E-33 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 Gene3D G3DSA:1.10.340.30 326 440 2.4E-32 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 SUPERFAMILY SSF48150 313 488 7.15E-39 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 SMART SM01009 208 323 2.2E-46 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 329 476 1.7E-5 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 Gene3D G3DSA:1.10.1670.10 441 491 6.7E-18 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 LK06_RS27930 b0c5dd3bd0c11bc731aefc0a42b934f7 501 Gene3D G3DSA:1.10.10.60 141 189 1.6E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS08475 e5c1dccadd94ef73e78924546717677c 229 SUPERFAMILY SSF53335 52 205 1.96E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS08475 e5c1dccadd94ef73e78924546717677c 229 Pfam PF13578 Methyltransferase domain 56 184 2.8E-22 T 06-07-2017 LK06_RS08475 e5c1dccadd94ef73e78924546717677c 229 Gene3D G3DSA:3.40.50.150 55 187 1.1E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS18035 ffe7dde5170a8591d8dca40a2564f948 294 Gene3D G3DSA:1.25.40.10 60 169 9.6E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18035 ffe7dde5170a8591d8dca40a2564f948 294 Gene3D G3DSA:1.25.40.10 180 249 2.4E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18035 ffe7dde5170a8591d8dca40a2564f948 294 SUPERFAMILY SSF48452 58 182 3.48E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS26400 8b06bf95e3a0b9044796faea19839b32 276 Pfam PF04072 Leucine carboxyl methyltransferase 13 188 4.4E-48 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 LK06_RS26400 8b06bf95e3a0b9044796faea19839b32 276 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 257 1.9E-47 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 LK06_RS26400 8b06bf95e3a0b9044796faea19839b32 276 Gene3D G3DSA:3.40.50.150 30 200 4.2E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26400 8b06bf95e3a0b9044796faea19839b32 276 SUPERFAMILY SSF53335 10 274 5.82E-59 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS21695 3521fbfd788a713ea92a466c962c62b9 239 Gene3D G3DSA:1.10.443.10 39 235 1.1E-20 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS21695 3521fbfd788a713ea92a466c962c62b9 239 Pfam PF00589 Phage integrase family 173 231 1.1E-7 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS21695 3521fbfd788a713ea92a466c962c62b9 239 SUPERFAMILY SSF56349 2 236 1.88E-24 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS06575 738f1ff10610d8cb78b5a05adaf1fef8 540 Gene3D G3DSA:3.20.20.80 4 105 7.6E-100 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS06575 738f1ff10610d8cb78b5a05adaf1fef8 540 Gene3D G3DSA:3.20.20.80 184 476 7.6E-100 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS06575 738f1ff10610d8cb78b5a05adaf1fef8 540 Gene3D G3DSA:3.90.400.10 106 183 4.3E-28 T 06-07-2017 LK06_RS06575 738f1ff10610d8cb78b5a05adaf1fef8 540 Pfam PF11941 Domain of unknown function (DUF3459) 460 536 4.8E-6 T 06-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) LK06_RS06575 738f1ff10610d8cb78b5a05adaf1fef8 540 Pfam PF00128 Alpha amylase, catalytic domain 29 383 9.9E-79 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS06575 738f1ff10610d8cb78b5a05adaf1fef8 540 SUPERFAMILY SSF51445 4 474 4.08E-118 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS06575 738f1ff10610d8cb78b5a05adaf1fef8 540 SMART SM00642 14 407 9.2E-119 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 Gene3D G3DSA:3.20.20.70 13 478 3.3E-134 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 Pfam PF00571 CBS domain 156 206 4.3E-4 T 06-07-2017 IPR000644 CBS domain LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 Pfam PF00571 CBS domain 102 144 5.8E-6 T 06-07-2017 IPR000644 CBS domain LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 SUPERFAMILY SSF51412 206 477 1.83E-89 T 06-07-2017 LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 SUPERFAMILY SSF51412 14 96 1.83E-89 T 06-07-2017 LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 PIRSF PIRSF000130 4 483 3.0E-146 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 477 1.9E-100 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 5 480 4.1E-282 T 06-07-2017 IPR005991 IMP dehydrogenase-related 1 LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 SMART SM00116 101 149 0.67 T 06-07-2017 IPR000644 CBS domain LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 SMART SM00116 160 208 0.22 T 06-07-2017 IPR000644 CBS domain LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 SUPERFAMILY SSF54631 98 207 1.39E-19 T 06-07-2017 LK06_RS04040 9c461213480d5667a4921ab484f2baa7 483 SMART SM01240 14 478 4.5E-193 T 06-07-2017 LK06_RS29290 1e67ba321a50ef1638047a2dc85fe1b1 754 PIRSF PIRSF000379 13 754 0.0 T 06-07-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 LK06_RS29290 1e67ba321a50ef1638047a2dc85fe1b1 754 Gene3D G3DSA:3.20.70.20 14 753 2.5E-295 T 06-07-2017 LK06_RS29290 1e67ba321a50ef1638047a2dc85fe1b1 754 SUPERFAMILY SSF51998 14 753 1.16E-271 T 06-07-2017 LK06_RS29290 1e67ba321a50ef1638047a2dc85fe1b1 754 ProSitePatterns PS00850 Glycine radical domain signature. 724 732 - T 06-07-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site LK06_RS29290 1e67ba321a50ef1638047a2dc85fe1b1 754 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 16 754 0.0 T 06-07-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 LK06_RS29290 1e67ba321a50ef1638047a2dc85fe1b1 754 Pfam PF02901 Pyruvate formate lyase-like 29 613 1.8E-197 T 06-07-2017 IPR004184 Pyruvate formate lyase domain GO:0003824 LK06_RS29290 1e67ba321a50ef1638047a2dc85fe1b1 754 Pfam PF01228 Glycine radical 629 735 2.4E-39 T 06-07-2017 IPR001150 Glycine radical domain GO:0003824|GO:0008152 LK06_RS05035 89481088b91a52818ee3776f11be92ed 588 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 52 565 8.1E-253 T 06-07-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 LK06_RS05035 89481088b91a52818ee3776f11be92ed 588 SMART SM00382 265 419 1.2E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS05035 89481088b91a52818ee3776f11be92ed 588 Pfam PF16450 Proteasomal ATPase OB/ID domain 97 226 1.5E-52 T 06-07-2017 IPR032501 Proteasomal ATPase, OB/ID domain LK06_RS05035 89481088b91a52818ee3776f11be92ed 588 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 54 566 50.262 T 06-07-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 LK06_RS05035 89481088b91a52818ee3776f11be92ed 588 ProSitePatterns PS00674 AAA-protein family signature. 387 405 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 LK06_RS05035 89481088b91a52818ee3776f11be92ed 588 Gene3D G3DSA:3.40.50.300 217 434 5.7E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05035 89481088b91a52818ee3776f11be92ed 588 SUPERFAMILY SSF52540 475 514 4.67E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05035 89481088b91a52818ee3776f11be92ed 588 SUPERFAMILY SSF52540 227 434 4.67E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05035 89481088b91a52818ee3776f11be92ed 588 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 269 417 5.4E-47 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS15375 e1bfa9509be9e7265aba4bd1f46e3680 462 Gene3D G3DSA:2.40.50.100 8 102 2.0E-27 T 06-07-2017 LK06_RS15375 e1bfa9509be9e7265aba4bd1f46e3680 462 SUPERFAMILY SSF51230 9 101 1.31E-26 T 06-07-2017 IPR011053 Single hybrid motif LK06_RS15375 e1bfa9509be9e7265aba4bd1f46e3680 462 Gene3D G3DSA:4.10.320.10 160 209 1.3E-16 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS15375 e1bfa9509be9e7265aba4bd1f46e3680 462 Pfam PF00364 Biotin-requiring enzyme 11 81 2.8E-22 T 06-07-2017 IPR000089 Biotin/lipoyl attachment LK06_RS15375 e1bfa9509be9e7265aba4bd1f46e3680 462 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 231 459 6.7E-79 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS15375 e1bfa9509be9e7265aba4bd1f46e3680 462 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 34 63 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 LK06_RS15375 e1bfa9509be9e7265aba4bd1f46e3680 462 SUPERFAMILY SSF52777 221 459 1.6E-76 T 06-07-2017 LK06_RS15375 e1bfa9509be9e7265aba4bd1f46e3680 462 Pfam PF02817 e3 binding domain 163 197 9.5E-14 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS15375 e1bfa9509be9e7265aba4bd1f46e3680 462 SUPERFAMILY SSF47005 159 201 1.7E-10 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS15375 e1bfa9509be9e7265aba4bd1f46e3680 462 Gene3D G3DSA:3.30.559.10 221 459 1.6E-82 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 LK06_RS32335 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS32335 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS16850 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS16850 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS26200 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS26200 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS19565 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS19565 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS18075 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS18075 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS09675 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS09675 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS23115 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS23115 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS18000 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS18000 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS04440 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS04440 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS10525 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS10525 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS14290 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS14290 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS22965 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS22965 671852b45d6f34b1a844179c27fe4bbe 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS09300 4c6587cf0ed93c24a2f02a7ffff0dec4 259 Pfam PF00005 ABC transporter 25 172 3.0E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS09300 4c6587cf0ed93c24a2f02a7ffff0dec4 259 SUPERFAMILY SSF52540 6 236 3.55E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09300 4c6587cf0ed93c24a2f02a7ffff0dec4 259 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS09300 4c6587cf0ed93c24a2f02a7ffff0dec4 259 Gene3D G3DSA:3.40.50.300 6 233 6.4E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09300 4c6587cf0ed93c24a2f02a7ffff0dec4 259 SMART SM00382 34 228 7.2E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS15715 ab347fa00be0e103b8d1434507f20c5c 62 Gene3D G3DSA:3.30.70.20 1 61 1.5E-11 T 06-07-2017 LK06_RS15715 ab347fa00be0e103b8d1434507f20c5c 62 Pfam PF13459 4Fe-4S single cluster domain 3 59 4.5E-10 T 06-07-2017 LK06_RS15715 ab347fa00be0e103b8d1434507f20c5c 62 SUPERFAMILY SSF54862 1 61 7.85E-9 T 06-07-2017 LK06_RS15715 ab347fa00be0e103b8d1434507f20c5c 62 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.1E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS15715 ab347fa00be0e103b8d1434507f20c5c 62 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.1E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS15715 ab347fa00be0e103b8d1434507f20c5c 62 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 1.1E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS10955 a1ef955b3ee35e29ede6a102ede55a14 214 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 5 212 2.6E-64 T 06-07-2017 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD LK06_RS10955 a1ef955b3ee35e29ede6a102ede55a14 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 107 2.5E-16 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 LK06_RS10955 a1ef955b3ee35e29ede6a102ede55a14 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 212 8.7E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10955 a1ef955b3ee35e29ede6a102ede55a14 214 SUPERFAMILY SSF161098 15 204 6.28E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10955 a1ef955b3ee35e29ede6a102ede55a14 214 Gene3D G3DSA:1.10.3720.10 15 212 3.3E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS25515 8a4541ef85719c6312b52cbe9b0b6acd 223 Pfam PF02080 TrkA-C domain 149 213 4.8E-14 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS25515 8a4541ef85719c6312b52cbe9b0b6acd 223 SUPERFAMILY SSF116726 143 211 1.44E-9 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS25515 8a4541ef85719c6312b52cbe9b0b6acd 223 Gene3D G3DSA:3.30.70.1450 149 212 3.8E-8 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS25515 8a4541ef85719c6312b52cbe9b0b6acd 223 Gene3D G3DSA:3.40.50.720 2 140 1.1E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25515 8a4541ef85719c6312b52cbe9b0b6acd 223 Pfam PF02254 TrkA-N domain 3 116 3.5E-25 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LK06_RS25515 8a4541ef85719c6312b52cbe9b0b6acd 223 SUPERFAMILY SSF51735 2 140 5.51E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25515 8a4541ef85719c6312b52cbe9b0b6acd 223 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 7.3E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS25515 8a4541ef85719c6312b52cbe9b0b6acd 223 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 7.3E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS25515 8a4541ef85719c6312b52cbe9b0b6acd 223 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 7.3E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS25515 8a4541ef85719c6312b52cbe9b0b6acd 223 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 7.3E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS15265 8d844fda6338871e98d2f6843d5a6cd1 449 Gene3D G3DSA:1.10.10.10 4 67 8.3E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15265 8d844fda6338871e98d2f6843d5a6cd1 449 SUPERFAMILY SSF46785 4 70 5.17E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15265 8d844fda6338871e98d2f6843d5a6cd1 449 SMART SM00345 7 66 3.1E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS15265 8d844fda6338871e98d2f6843d5a6cd1 449 Gene3D G3DSA:3.40.640.10 117 336 7.3E-39 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS15265 8d844fda6338871e98d2f6843d5a6cd1 449 SUPERFAMILY SSF53383 89 440 2.86E-63 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS15265 8d844fda6338871e98d2f6843d5a6cd1 449 Pfam PF00155 Aminotransferase class I and II 121 435 4.1E-17 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS15265 8d844fda6338871e98d2f6843d5a6cd1 449 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.2E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS15265 8d844fda6338871e98d2f6843d5a6cd1 449 Gene3D G3DSA:3.90.1150.10 358 439 2.2E-4 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS02205 c5cdab27aa7035e9c30e9d4019c79262 354 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 212 342 1.3E-18 T 06-07-2017 IPR012328 Chalcone/stilbene synthase, C-terminal LK06_RS02205 c5cdab27aa7035e9c30e9d4019c79262 354 PIRSF PIRSF000451 1 349 1.9E-112 T 06-07-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 LK06_RS02205 c5cdab27aa7035e9c30e9d4019c79262 354 SUPERFAMILY SSF53901 204 346 1.3E-34 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS02205 c5cdab27aa7035e9c30e9d4019c79262 354 Pfam PF08392 FAE1/Type III polyketide synthase-like protein 15 197 5.4E-14 T 06-07-2017 IPR013601 FAE1/Type III polyketide synthase-like protein GO:0006633|GO:0016020|GO:0016747 KEGG: 00062+2.3.1.199|KEGG: 00650+2.3.1.19|MetaCyc: PWY-5080|MetaCyc: PWY-5972|MetaCyc: PWY-6433|MetaCyc: PWY-6598|MetaCyc: PWY-7036|MetaCyc: PWY-7601|MetaCyc: PWY-7602|MetaCyc: PWY-7619|MetaCyc: PWY-7724|MetaCyc: PWY-7725 LK06_RS02205 c5cdab27aa7035e9c30e9d4019c79262 354 Gene3D G3DSA:3.40.47.10 205 346 6.3E-32 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS02205 c5cdab27aa7035e9c30e9d4019c79262 354 SUPERFAMILY SSF53901 2 198 5.76E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS02205 c5cdab27aa7035e9c30e9d4019c79262 354 Gene3D G3DSA:3.40.47.10 2 200 3.7E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS22445 dc974e3645f227a4961d65d209ff2052 254 SMART SM00345 27 84 7.9E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS22445 dc974e3645f227a4961d65d209ff2052 254 Pfam PF07702 UTRA domain 104 244 1.3E-43 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS22445 dc974e3645f227a4961d65d209ff2052 254 SUPERFAMILY SSF64288 72 251 3.45E-56 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS22445 dc974e3645f227a4961d65d209ff2052 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 2.6E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS22445 dc974e3645f227a4961d65d209ff2052 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 2.6E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS22445 dc974e3645f227a4961d65d209ff2052 254 SMART SM00866 104 244 4.0E-45 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS22445 dc974e3645f227a4961d65d209ff2052 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 35 84 5.6E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS22445 dc974e3645f227a4961d65d209ff2052 254 SUPERFAMILY SSF46785 17 88 1.04E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22445 dc974e3645f227a4961d65d209ff2052 254 Gene3D G3DSA:1.10.10.10 18 81 4.3E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22445 dc974e3645f227a4961d65d209ff2052 254 Gene3D G3DSA:3.40.1410.10 82 251 1.0E-57 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS09470 33d9e890ccc0e11e628b7fc28df6b7e5 116 Gene3D G3DSA:3.30.428.10 4 116 1.7E-34 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS09470 33d9e890ccc0e11e628b7fc28df6b7e5 116 SUPERFAMILY SSF54197 6 115 2.32E-31 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS09470 33d9e890ccc0e11e628b7fc28df6b7e5 116 Pfam PF01230 HIT domain 18 109 1.3E-22 T 06-07-2017 IPR001310 Histidine triad (HIT) protein LK06_RS09470 33d9e890ccc0e11e628b7fc28df6b7e5 116 PRINTS PR00332 Histidine triad family signature 10 26 6.8E-18 T 06-07-2017 IPR001310 Histidine triad (HIT) protein LK06_RS09470 33d9e890ccc0e11e628b7fc28df6b7e5 116 PRINTS PR00332 Histidine triad family signature 31 49 6.8E-18 T 06-07-2017 IPR001310 Histidine triad (HIT) protein LK06_RS09470 33d9e890ccc0e11e628b7fc28df6b7e5 116 PRINTS PR00332 Histidine triad family signature 96 106 6.8E-18 T 06-07-2017 IPR001310 Histidine triad (HIT) protein LK06_RS30835 838e7cc3f6c1f13497797e14d92c0ed8 497 SUPERFAMILY SSF103473 8 204 1.7E-41 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS30835 838e7cc3f6c1f13497797e14d92c0ed8 497 SUPERFAMILY SSF103473 215 472 1.01E-20 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS30835 838e7cc3f6c1f13497797e14d92c0ed8 497 Gene3D G3DSA:1.20.1250.20 27 204 1.4E-30 T 06-07-2017 LK06_RS30835 838e7cc3f6c1f13497797e14d92c0ed8 497 Gene3D G3DSA:1.20.1250.20 274 474 7.2E-13 T 06-07-2017 LK06_RS30835 838e7cc3f6c1f13497797e14d92c0ed8 497 Pfam PF07690 Major Facilitator Superfamily 30 422 6.2E-36 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS04080 5a9402c74abaf04b14286a0037b4e396 400 Gene3D G3DSA:3.40.50.10300 181 399 2.6E-79 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 LK06_RS04080 5a9402c74abaf04b14286a0037b4e396 400 SUPERFAMILY SSF52507 2 176 1.44E-58 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS04080 5a9402c74abaf04b14286a0037b4e396 400 SUPERFAMILY SSF102645 176 398 1.57E-67 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 LK06_RS04080 5a9402c74abaf04b14286a0037b4e396 400 Pfam PF02441 Flavoprotein 5 130 5.7E-32 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS04080 5a9402c74abaf04b14286a0037b4e396 400 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 395 2.1E-120 T 06-07-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 LK06_RS04080 5a9402c74abaf04b14286a0037b4e396 400 Gene3D G3DSA:3.40.50.1950 3 177 3.1E-61 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS04080 5a9402c74abaf04b14286a0037b4e396 400 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 369 4.7E-69 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 LK06_RS04760 042e5813b8cb53260b564521069bc59e 424 SUPERFAMILY SSF51445 114 371 4.96E-18 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS04760 042e5813b8cb53260b564521069bc59e 424 Pfam PF02638 Glycosyl hydrolase-like 10 60 377 6.4E-88 T 06-07-2017 IPR003790 Glycosyl hydrolase-like 10 LK06_RS21100 61fb5cf88ca34b5b2a57d723da258e05 255 Pfam PF00005 ABC transporter 38 184 1.3E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS21100 61fb5cf88ca34b5b2a57d723da258e05 255 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS21100 61fb5cf88ca34b5b2a57d723da258e05 255 SMART SM00382 47 233 1.8E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS21100 61fb5cf88ca34b5b2a57d723da258e05 255 SUPERFAMILY SSF52540 19 237 2.02E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21100 61fb5cf88ca34b5b2a57d723da258e05 255 Gene3D G3DSA:3.40.50.300 19 236 3.7E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00480 87cb70e44e4c45379435390975c7a91c 482 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 473 78.818 T 06-07-2017 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS00480 87cb70e44e4c45379435390975c7a91c 482 Gene3D G3DSA:3.90.1260.10 176 372 6.2E-62 T 06-07-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS00480 87cb70e44e4c45379435390975c7a91c 482 Gene3D G3DSA:3.40.50.620 4 175 5.3E-40 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS00480 87cb70e44e4c45379435390975c7a91c 482 Pfam PF00764 Arginosuccinate synthase 16 404 2.6E-55 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS00480 87cb70e44e4c45379435390975c7a91c 482 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS00480 87cb70e44e4c45379435390975c7a91c 482 SUPERFAMILY SSF52402 5 185 2.88E-30 T 06-07-2017 LK06_RS00480 87cb70e44e4c45379435390975c7a91c 482 SUPERFAMILY SSF69864 190 437 6.54E-75 T 06-07-2017 LK06_RS00480 87cb70e44e4c45379435390975c7a91c 482 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS00480 87cb70e44e4c45379435390975c7a91c 482 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 1.6E-137 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS00480 87cb70e44e4c45379435390975c7a91c 482 Gene3D G3DSA:1.10.287.400 377 438 1.4E-28 T 06-07-2017 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS03475 28860ebd73f79020e3659f6f6086f6fe 400 Gene3D G3DSA:1.10.443.10 192 384 5.5E-18 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS03475 28860ebd73f79020e3659f6f6086f6fe 400 SUPERFAMILY SSF56349 180 384 8.83E-17 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS03475 28860ebd73f79020e3659f6f6086f6fe 400 Pfam PF00589 Phage integrase family 192 383 3.8E-12 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 175 194 2.7E-23 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 471 484 2.7E-23 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 408 422 2.7E-23 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 336 358 2.7E-23 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 393 407 2.7E-23 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 Gene3D G3DSA:3.40.710.10 295 517 2.2E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 144 288 1.2E-25 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 297 511 8.2E-50 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 SUPERFAMILY SSF56601 150 506 9.09E-63 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 298 493 1.2E-40 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS13820 b401177e0f1cbc9104aca5399ac6d989 518 Gene3D G3DSA:3.40.710.10 147 240 8.5E-12 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS12805 987e35adffe59a10b25e53ddbcbd1a3c 768 Pfam PF04738 Lantibiotic dehydratase, C terminus 88 518 3.0E-23 T 06-07-2017 IPR006827 Lantibiotic dehydratase, C-terminal LK06_RS22195 1ac8a4e6bb667b36fda1e4a308b5517b 165 SUPERFAMILY SSF46767 56 118 2.22E-14 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LK06_RS22195 1ac8a4e6bb667b36fda1e4a308b5517b 165 Gene3D G3DSA:1.10.10.10 57 115 1.4E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22195 1ac8a4e6bb667b36fda1e4a308b5517b 165 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 58 117 4.1E-17 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LK06_RS06475 702cdb06639745ed69031ab9ad391c8c 378 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 96 365 2.5E-76 T 06-07-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 LK06_RS06475 702cdb06639745ed69031ab9ad391c8c 378 SUPERFAMILY SSF101960 21 374 1.57E-93 T 06-07-2017 LK06_RS06475 702cdb06639745ed69031ab9ad391c8c 378 Pfam PF01458 Uncharacterized protein family (UPF0051) 127 348 6.1E-72 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 LK06_RS22225 aa739f3055a10c69196f39dc4836a016 85 Gene3D G3DSA:3.40.30.10 4 84 1.2E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS22225 aa739f3055a10c69196f39dc4836a016 85 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 4 84 2.4E-28 T 06-07-2017 IPR011915 Glutaredoxin-like protein, actinobacteria LK06_RS22225 aa739f3055a10c69196f39dc4836a016 85 SUPERFAMILY SSF52833 4 77 2.95E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS22225 aa739f3055a10c69196f39dc4836a016 85 Pfam PF00462 Glutaredoxin 5 60 9.6E-14 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 LK06_RS22225 aa739f3055a10c69196f39dc4836a016 85 ProSitePatterns PS00194 Thioredoxin family active site. 5 23 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 LK06_RS12015 96cfb690ba6d7b2bd4ce1a11e8572a3b 174 PIRSF PIRSF001338 1 163 7.3E-69 T 06-07-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 LK06_RS12015 96cfb690ba6d7b2bd4ce1a11e8572a3b 174 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 2.5E-64 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 LK06_RS12015 96cfb690ba6d7b2bd4ce1a11e8572a3b 174 Pfam PF00731 AIR carboxylase 5 150 3.3E-65 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 LK06_RS12015 96cfb690ba6d7b2bd4ce1a11e8572a3b 174 Gene3D G3DSA:3.40.50.7700 2 160 1.8E-73 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 LK06_RS12015 96cfb690ba6d7b2bd4ce1a11e8572a3b 174 SMART SM01001 3 152 1.5E-95 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 LK06_RS12015 96cfb690ba6d7b2bd4ce1a11e8572a3b 174 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 156 32.197 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 LK06_RS12015 96cfb690ba6d7b2bd4ce1a11e8572a3b 174 SUPERFAMILY SSF52255 3 161 8.89E-66 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 84 999 17.08 T 06-07-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 88 312 4.2E-48 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 631 843 3.8E-37 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 SUPERFAMILY SSF81301 59 322 1.11E-66 T 06-07-2017 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 Gene3D G3DSA:3.30.460.10 164 323 1.2E-54 T 06-07-2017 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 Gene3D G3DSA:3.30.460.10 693 852 2.8E-49 T 06-07-2017 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 SUPERFAMILY SSF81593 858 1009 1.88E-36 T 06-07-2017 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 Pfam PF08335 GlnD PII-uridylyltransferase 336 476 1.2E-35 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 Pfam PF08335 GlnD PII-uridylyltransferase 866 1008 1.7E-20 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 SUPERFAMILY SSF81301 553 852 7.19E-56 T 06-07-2017 LK06_RS08130 3c641308421d558592e8a5ffc0ed17dd 1021 SUPERFAMILY SSF81593 329 477 1.1E-38 T 06-07-2017 LK06_RS12140 b6f40987f01c4c72e6f017b6d85ff66a 329 Gene3D G3DSA:3.40.50.300 20 328 5.6E-106 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12140 b6f40987f01c4c72e6f017b6d85ff66a 329 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 102 248 6.0E-11 T 06-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 LK06_RS12140 b6f40987f01c4c72e6f017b6d85ff66a 329 PIRSF PIRSF000545 11 329 9.6E-144 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 LK06_RS12140 b6f40987f01c4c72e6f017b6d85ff66a 329 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 20 328 5.8E-127 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 LK06_RS12140 b6f40987f01c4c72e6f017b6d85ff66a 329 Hamap MF_00215 Pantothenate kinase [coaA]. 1 329 172.649 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 LK06_RS12140 b6f40987f01c4c72e6f017b6d85ff66a 329 SUPERFAMILY SSF52540 18 327 1.14E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23640 62e69e68e3b49f6f086bec6610128cbe 872 Pfam PF11897 Protein of unknown function (DUF3417) 13 120 1.3E-34 T 06-07-2017 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 LK06_RS23640 62e69e68e3b49f6f086bec6610128cbe 872 Gene3D G3DSA:3.40.50.2000 24 424 9.6E-89 T 06-07-2017 LK06_RS23640 62e69e68e3b49f6f086bec6610128cbe 872 PIRSF PIRSF000460 1 802 2.1E-254 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 LK06_RS23640 62e69e68e3b49f6f086bec6610128cbe 872 SUPERFAMILY SSF53756 4 749 1.66E-197 T 06-07-2017 LK06_RS23640 62e69e68e3b49f6f086bec6610128cbe 872 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 107 719 4.8E-231 T 06-07-2017 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 LK06_RS23640 62e69e68e3b49f6f086bec6610128cbe 872 Gene3D G3DSA:3.40.50.2000 425 723 8.0E-90 T 06-07-2017 LK06_RS23640 62e69e68e3b49f6f086bec6610128cbe 872 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 607 619 - T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 LK06_RS23640 62e69e68e3b49f6f086bec6610128cbe 872 Pfam PF00343 Carbohydrate phosphorylase 125 170 3.1E-6 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 LK06_RS23640 62e69e68e3b49f6f086bec6610128cbe 872 Pfam PF00343 Carbohydrate phosphorylase 271 629 1.5E-15 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 LK06_RS12180 b7ef8ecbfeb60fc83e937a79eb3381f2 134 Gene3D G3DSA:3.30.420.80 11 134 1.8E-58 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 LK06_RS12180 b7ef8ecbfeb60fc83e937a79eb3381f2 134 Pfam PF00411 Ribosomal protein S11 24 133 1.6E-48 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 LK06_RS12180 b7ef8ecbfeb60fc83e937a79eb3381f2 134 PIRSF PIRSF002131 4 134 2.7E-54 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 LK06_RS12180 b7ef8ecbfeb60fc83e937a79eb3381f2 134 SUPERFAMILY SSF53137 19 134 7.19E-50 T 06-07-2017 LK06_RS12180 b7ef8ecbfeb60fc83e937a79eb3381f2 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 06-07-2017 IPR018102 Ribosomal S11, conserved site LK06_RS12180 b7ef8ecbfeb60fc83e937a79eb3381f2 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 6 134 34.437 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 LK06_RS12180 b7ef8ecbfeb60fc83e937a79eb3381f2 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 1.7E-59 T 06-07-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 Gene3D G3DSA:2.30.38.10 435 507 2.1E-25 T 06-07-2017 LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 Gene3D G3DSA:1.10.1200.10 1126 1205 2.2E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 Pfam PF00550 Phosphopantetheine attachment site 1138 1199 4.5E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 Gene3D G3DSA:3.40.50.980 236 401 3.2E-24 T 06-07-2017 LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 817 1006 2.3E-12 T 06-07-2017 LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 SUPERFAMILY SSF56801 65 616 8.77E-90 T 06-07-2017 LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 Gene3D G3DSA:3.40.50.720 815 1039 8.0E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 Gene3D G3DSA:3.40.50.980 71 235 2.8E-14 T 06-07-2017 LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 SMART SM00823 Phosphopantetheine attachment site 1136 1204 5.3E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1159 1174 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 Pfam PF00501 AMP-binding enzyme 94 515 1.8E-55 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 SUPERFAMILY SSF51735 814 1045 3.89E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 SUPERFAMILY SSF47336 1129 1200 2.62E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 SUPERFAMILY SSF51735 630 804 6.33E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 SMART SM01294 1133 1200 0.0042 T 06-07-2017 LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 Pfam PF08659 KR domain 817 1004 2.5E-32 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21050 5126143ffe63aa9f8bc23052d98f5681 1209 Gene3D G3DSA:3.30.300.30 508 612 2.9E-12 T 06-07-2017 LK06_RS01460 a29dff4e282d863ab86fea79279dfda6 162 SMART SM00347 27 131 1.8E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS01460 a29dff4e282d863ab86fea79279dfda6 162 Pfam PF01047 MarR family 34 96 1.1E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS01460 a29dff4e282d863ab86fea79279dfda6 162 SUPERFAMILY SSF46785 10 139 9.43E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01460 a29dff4e282d863ab86fea79279dfda6 162 Gene3D G3DSA:1.10.10.10 9 146 2.2E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29040 00eae49b340f44dd4bb5e5d3feccdf4a 300 Pfam PF01261 Xylose isomerase-like TIM barrel 34 236 1.0E-27 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS29040 00eae49b340f44dd4bb5e5d3feccdf4a 300 SUPERFAMILY SSF51658 5 283 9.81E-49 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS29040 00eae49b340f44dd4bb5e5d3feccdf4a 300 Gene3D G3DSA:3.20.20.150 6 299 2.7E-65 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS03855 f098024dfcfece59cfc6f152d7855329 264 SUPERFAMILY SSF53448 24 235 3.3E-42 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS03855 f098024dfcfece59cfc6f152d7855329 264 Gene3D G3DSA:3.90.550.10 25 235 5.1E-23 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS03855 f098024dfcfece59cfc6f152d7855329 264 Pfam PF00535 Glycosyl transferase family 2 25 187 6.1E-28 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS31250 73e13452bc8500c006220de73a03ebf5 571 SUPERFAMILY SSF53328 4 166 2.35E-24 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS31250 73e13452bc8500c006220de73a03ebf5 571 SUPERFAMILY SSF50486 175 255 2.62E-8 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 LK06_RS31250 73e13452bc8500c006220de73a03ebf5 571 Pfam PF00378 Enoyl-CoA hydratase/isomerase 326 513 5.6E-20 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS31250 73e13452bc8500c006220de73a03ebf5 571 Pfam PF02911 Formyl transferase, C-terminal domain 175 256 3.0E-7 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS31250 73e13452bc8500c006220de73a03ebf5 571 PIRSF PIRSF006787 1 569 2.3E-231 T 06-07-2017 IPR009188 [NiFe]-hydrogenase maturation factor, HypX/HoxX type LK06_RS31250 73e13452bc8500c006220de73a03ebf5 571 SUPERFAMILY SSF52096 298 541 6.92E-37 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS31250 73e13452bc8500c006220de73a03ebf5 571 Gene3D G3DSA:3.90.226.10 295 516 2.6E-29 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS31250 73e13452bc8500c006220de73a03ebf5 571 Gene3D G3DSA:3.40.50.170 40 166 2.5E-19 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS31250 73e13452bc8500c006220de73a03ebf5 571 Gene3D G3DSA:3.10.25.10 176 255 1.5E-5 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS12495 8985c0420e0c7fe88b9fa2b6683a67ea 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 23 47 8.7E-8 T 06-07-2017 LK06_RS12495 8985c0420e0c7fe88b9fa2b6683a67ea 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 8.7E-8 T 06-07-2017 LK06_RS12495 8985c0420e0c7fe88b9fa2b6683a67ea 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 8.7E-8 T 06-07-2017 LK06_RS12495 8985c0420e0c7fe88b9fa2b6683a67ea 486 Pfam PF07690 Major Facilitator Superfamily 26 415 6.6E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS12495 8985c0420e0c7fe88b9fa2b6683a67ea 486 SUPERFAMILY SSF103473 11 203 7.59E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS12495 8985c0420e0c7fe88b9fa2b6683a67ea 486 SUPERFAMILY SSF103473 253 462 7.59E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS12495 8985c0420e0c7fe88b9fa2b6683a67ea 486 Gene3D G3DSA:1.20.1250.20 19 193 5.5E-28 T 06-07-2017 LK06_RS12495 8985c0420e0c7fe88b9fa2b6683a67ea 486 Gene3D G3DSA:1.20.1250.20 265 463 3.2E-25 T 06-07-2017 LK06_RS12495 8985c0420e0c7fe88b9fa2b6683a67ea 486 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 424 3.1E-89 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS21505 0dc49a55d17ef4af2a77b2f91a21de26 402 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 400 2.1E-119 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 LK06_RS21505 0dc49a55d17ef4af2a77b2f91a21de26 402 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 401 25.281 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 LK06_RS21505 0dc49a55d17ef4af2a77b2f91a21de26 402 Pfam PF02601 Exonuclease VII, large subunit 129 331 4.4E-59 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 LK06_RS21505 0dc49a55d17ef4af2a77b2f91a21de26 402 Pfam PF02601 Exonuclease VII, large subunit 326 398 5.1E-11 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 LK06_RS21505 0dc49a55d17ef4af2a77b2f91a21de26 402 Pfam PF13742 OB-fold nucleic acid binding domain 12 105 4.6E-16 T 06-07-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 650 678 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 SUPERFAMILY SSF56796 467 879 2.09E-112 T 06-07-2017 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 738 758 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 Pfam PF00171 Aldehyde dehydrogenase family 23 281 1.2E-21 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 Pfam PF00465 Iron-containing alcohol dehydrogenase 476 869 2.6E-112 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 SUPERFAMILY SSF53720 24 472 8.25E-76 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 Gene3D G3DSA:1.20.1090.10 662 878 4.3E-69 T 06-07-2017 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 PIRSF PIRSF000111 8 881 0.0 T 06-07-2017 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00592+1.1.1.1|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00650+1.2.1.10|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7085|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7180|MetaCyc: PWY-7396 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 Gene3D G3DSA:3.40.50.1970 471 661 2.9E-58 T 06-07-2017 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 Gene3D G3DSA:3.40.605.10 23 239 2.0E-24 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 Gene3D G3DSA:3.40.309.10 240 288 4.1E-24 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS29310 b778435e5d71cf97cc3ebcf201f4b591 895 Gene3D G3DSA:3.40.309.10 332 423 4.1E-24 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS29120 b9a60b35f8ef14d40ad58045cfe41049 180 Pfam PF00578 AhpC/TSA family 42 161 2.2E-20 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LK06_RS29120 b9a60b35f8ef14d40ad58045cfe41049 180 Gene3D G3DSA:3.40.30.10 6 180 2.8E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS29120 b9a60b35f8ef14d40ad58045cfe41049 180 SUPERFAMILY SSF52833 6 180 4.69E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS28695 1791dabc4d6db0bab17300dbc531f910 353 SUPERFAMILY SSF56796 7 347 3.66E-56 T 06-07-2017 LK06_RS28695 1791dabc4d6db0bab17300dbc531f910 353 Gene3D G3DSA:3.40.50.1970 8 157 7.0E-26 T 06-07-2017 LK06_RS28695 1791dabc4d6db0bab17300dbc531f910 353 PIRSF PIRSF000112 2 353 2.7E-93 T 06-07-2017 LK06_RS28695 1791dabc4d6db0bab17300dbc531f910 353 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 270 5.8E-52 T 06-07-2017 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295 LK06_RS28695 1791dabc4d6db0bab17300dbc531f910 353 Gene3D G3DSA:1.20.1090.10 159 347 8.6E-60 T 06-07-2017 LK06_RS31965 2840a59dfe514f7a1fde0e6bb7bfe6ac 535 Pfam PF05345 Putative Ig domain 320 360 6.7E-10 T 06-07-2017 IPR008009 Putative Ig LK06_RS31965 2840a59dfe514f7a1fde0e6bb7bfe6ac 535 SUPERFAMILY SSF49313 290 375 5.34E-12 T 06-07-2017 IPR015919 Cadherin-like GO:0005509|GO:0016020 LK06_RS31965 2840a59dfe514f7a1fde0e6bb7bfe6ac 535 SUPERFAMILY SSF53649 34 270 1.64E-7 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 LK06_RS31965 2840a59dfe514f7a1fde0e6bb7bfe6ac 535 Gene3D G3DSA:3.40.720.10 36 178 3.1E-4 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 LK06_RS31965 2840a59dfe514f7a1fde0e6bb7bfe6ac 535 SMART SM00736 289 378 0.0023 T 06-07-2017 IPR006644 Dystroglycan-type cadherin-like GO:0016020 LK06_RS31965 2840a59dfe514f7a1fde0e6bb7bfe6ac 535 Pfam PF04185 Phosphoesterase family 55 265 6.2E-31 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 LK06_RS31965 2840a59dfe514f7a1fde0e6bb7bfe6ac 535 Gene3D G3DSA:2.60.40.10 289 373 1.3E-11 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS04635 fdfaaf6edf4f16a042e8964bf10b9f3d 188 SUPERFAMILY SSF46689 10 69 8.48E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS04635 fdfaaf6edf4f16a042e8964bf10b9f3d 188 SUPERFAMILY SSF48498 84 182 2.55E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS04635 fdfaaf6edf4f16a042e8964bf10b9f3d 188 Gene3D G3DSA:1.10.357.10 11 185 8.2E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS04635 fdfaaf6edf4f16a042e8964bf10b9f3d 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 6.7E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS03055 7e5356f457630115fdf7619ea12c7465 317 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 16 277 2.2E-100 T 06-07-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 LK06_RS03055 7e5356f457630115fdf7619ea12c7465 317 Gene3D G3DSA:3.90.550.10 17 285 1.8E-72 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS03055 7e5356f457630115fdf7619ea12c7465 317 SUPERFAMILY SSF53448 17 290 1.06E-63 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS03055 7e5356f457630115fdf7619ea12c7465 317 Pfam PF00483 Nucleotidyl transferase 18 276 2.7E-25 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LK06_RS05190 11447537b44b30b50f7b77f07d71bd7f 77 Pfam PF03777 Small secreted domain (DUF320) 21 76 3.5E-30 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS06250 7e65307b67acd9f8ed271f159d84b707 202 SUPERFAMILY SSF52540 12 202 4.86E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06250 7e65307b67acd9f8ed271f159d84b707 202 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 202 2.0E-67 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 LK06_RS06250 7e65307b67acd9f8ed271f159d84b707 202 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 202 2.2E-57 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 LK06_RS06250 7e65307b67acd9f8ed271f159d84b707 202 Gene3D G3DSA:3.40.50.300 10 202 5.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06250 7e65307b67acd9f8ed271f159d84b707 202 PIRSF PIRSF015617 1 202 2.6E-63 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 LK06_RS32230 31d5eab846cc076fc3f90bd7451d0852 281 SUPERFAMILY SSF46785 3 67 9.08E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32230 31d5eab846cc076fc3f90bd7451d0852 281 Gene3D G3DSA:1.10.10.10 74 145 3.6E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32230 31d5eab846cc076fc3f90bd7451d0852 281 Gene3D G3DSA:1.10.10.10 4 68 1.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32230 31d5eab846cc076fc3f90bd7451d0852 281 SUPERFAMILY SSF46785 74 127 3.33E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32230 31d5eab846cc076fc3f90bd7451d0852 281 SMART SM00345 6 65 1.2E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS32230 31d5eab846cc076fc3f90bd7451d0852 281 SMART SM00345 78 140 0.074 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS32230 31d5eab846cc076fc3f90bd7451d0852 281 Pfam PF00392 Bacterial regulatory proteins, gntR family 76 124 9.7E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS32230 31d5eab846cc076fc3f90bd7451d0852 281 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 65 7.7E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS20505 c1990d571963e077657863fbc28a92c5 302 Pfam PF03631 Virulence factor BrkB 33 280 3.1E-44 T 06-07-2017 IPR017039 Virulence factor BrkB LK06_RS20505 c1990d571963e077657863fbc28a92c5 302 PIRSF PIRSF035875 13 298 7.0E-23 T 06-07-2017 IPR017039 Virulence factor BrkB LK06_RS07680 d41c409def699398232c4f4af62823ba 118 SUPERFAMILY SSF89360 14 108 7.06E-28 T 06-07-2017 IPR000361 FeS cluster biogenesis LK06_RS07680 d41c409def699398232c4f4af62823ba 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 100 117 - T 06-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site LK06_RS07680 d41c409def699398232c4f4af62823ba 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 14 115 1.2E-19 T 06-07-2017 IPR000361 FeS cluster biogenesis LK06_RS07680 d41c409def699398232c4f4af62823ba 118 Gene3D G3DSA:2.60.300.12 14 108 1.2E-28 T 06-07-2017 IPR000361 FeS cluster biogenesis LK06_RS07680 d41c409def699398232c4f4af62823ba 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 14 118 4.1E-36 T 06-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 LK06_RS30355 6578d8491d4e9b19d69d64f8e68e90cb 312 TIGRFAM TIGR03814 Gln_ase: glutaminase A 16 312 4.1E-120 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 LK06_RS30355 6578d8491d4e9b19d69d64f8e68e90cb 312 Gene3D G3DSA:3.40.710.10 13 312 3.6E-114 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS30355 6578d8491d4e9b19d69d64f8e68e90cb 312 Hamap MF_00313 Glutaminase [glsA]. 12 312 45.081 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 LK06_RS30355 6578d8491d4e9b19d69d64f8e68e90cb 312 Pfam PF04960 Glutaminase 30 312 6.7E-107 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 LK06_RS30355 6578d8491d4e9b19d69d64f8e68e90cb 312 SUPERFAMILY SSF56601 14 312 9.92E-104 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS06320 54d8dc6c4f29dd805fa9ca7b93a9a48d 281 SMART SM00062 50 272 3.1E-58 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LK06_RS06320 54d8dc6c4f29dd805fa9ca7b93a9a48d 281 SUPERFAMILY SSF53850 12 270 2.85E-58 T 06-07-2017 LK06_RS06320 54d8dc6c4f29dd805fa9ca7b93a9a48d 281 SMART SM00079 50 271 0.0048 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 LK06_RS06320 54d8dc6c4f29dd805fa9ca7b93a9a48d 281 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 270 7.5E-58 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LK06_RS06320 54d8dc6c4f29dd805fa9ca7b93a9a48d 281 Gene3D G3DSA:3.40.190.10 49 128 1.8E-36 T 06-07-2017 LK06_RS06320 54d8dc6c4f29dd805fa9ca7b93a9a48d 281 Gene3D G3DSA:3.40.190.10 233 270 1.8E-36 T 06-07-2017 LK06_RS06320 54d8dc6c4f29dd805fa9ca7b93a9a48d 281 Gene3D G3DSA:3.40.190.10 129 232 5.9E-24 T 06-07-2017 LK06_RS28860 6f914cf02f61ff6c54a39d47f059b5eb 306 SMART SM00861 2 167 1.5E-19 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS28860 6f914cf02f61ff6c54a39d47f059b5eb 306 Pfam PF02779 Transketolase, pyrimidine binding domain 4 164 6.0E-21 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS28860 6f914cf02f61ff6c54a39d47f059b5eb 306 SUPERFAMILY SSF52518 3 163 3.64E-31 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28860 6f914cf02f61ff6c54a39d47f059b5eb 306 Gene3D G3DSA:3.40.50.920 178 293 2.0E-6 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS28860 6f914cf02f61ff6c54a39d47f059b5eb 306 Gene3D G3DSA:3.40.50.970 3 166 2.3E-25 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28860 6f914cf02f61ff6c54a39d47f059b5eb 306 SUPERFAMILY SSF52922 177 293 1.22E-9 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS08820 7729038bb9435116e2a4e8d08321c3a4 281 Pfam PF14472 Domain of unknown function (DUF4429) 12 106 1.7E-15 T 06-07-2017 IPR027860 Domain of unknown function DUF4429 LK06_RS08820 7729038bb9435116e2a4e8d08321c3a4 281 Pfam PF14472 Domain of unknown function (DUF4429) 137 227 4.6E-38 T 06-07-2017 IPR027860 Domain of unknown function DUF4429 LK06_RS08820 7729038bb9435116e2a4e8d08321c3a4 281 Pfam PF09851 Short C-terminal domain 251 278 1.3E-7 T 06-07-2017 IPR018649 SHOCT domain LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 Pfam PF00672 HAMP domain 158 226 5.2E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 494 6.2E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 SMART SM00387 385 496 1.1E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 Gene3D G3DSA:3.30.565.10 368 497 1.5E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 Gene3D G3DSA:3.30.565.10 291 322 1.5E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 SMART SM00388 238 305 6.9E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 SUPERFAMILY SSF55874 349 497 2.1E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 304 2.2E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 436 1.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 494 1.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 475 1.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 450 1.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 Gene3D G3DSA:1.10.287.130 239 290 4.5E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 SMART SM00304 177 230 2.0E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 SUPERFAMILY SSF158472 177 225 3.14E-6 T 06-07-2017 LK06_RS14895 6ee417ab44139c4642b019b80f25d787 520 SUPERFAMILY SSF47384 223 304 8.63E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS20980 15a3f634b35a71bbfc5606a519aaf8e2 409 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 312 3.0E-80 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS20980 15a3f634b35a71bbfc5606a519aaf8e2 409 SUPERFAMILY SSF55021 335 387 1.68E-5 T 06-07-2017 LK06_RS20980 15a3f634b35a71bbfc5606a519aaf8e2 409 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 31 407 2.0E-131 T 06-07-2017 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 LK06_RS20980 15a3f634b35a71bbfc5606a519aaf8e2 409 Gene3D G3DSA:3.30.70.260 333 384 5.2E-6 T 06-07-2017 LK06_RS20980 15a3f634b35a71bbfc5606a519aaf8e2 409 SUPERFAMILY SSF53686 13 321 1.44E-94 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS20980 15a3f634b35a71bbfc5606a519aaf8e2 409 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 LK06_RS20980 15a3f634b35a71bbfc5606a519aaf8e2 409 Gene3D G3DSA:3.40.50.1100 80 330 9.4E-78 T 06-07-2017 LK06_RS24630 e3e99a93f4f770768ab133c7866b431b 386 SUPERFAMILY SSF52540 14 250 2.32E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24630 e3e99a93f4f770768ab133c7866b431b 386 SUPERFAMILY SSF50331 245 368 1.16E-17 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal LK06_RS24630 e3e99a93f4f770768ab133c7866b431b 386 Gene3D G3DSA:3.40.50.300 5 244 3.0E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24630 e3e99a93f4f770768ab133c7866b431b 386 Gene3D G3DSA:2.40.50.100 246 322 1.0E-5 T 06-07-2017 LK06_RS24630 e3e99a93f4f770768ab133c7866b431b 386 Pfam PF00005 ABC transporter 30 169 6.3E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS24630 e3e99a93f4f770768ab133c7866b431b 386 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 44 366 8.8E-112 T 06-07-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 LK06_RS24630 e3e99a93f4f770768ab133c7866b431b 386 Pfam PF08402 TOBE domain 288 368 9.4E-15 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 LK06_RS24630 e3e99a93f4f770768ab133c7866b431b 386 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS24630 e3e99a93f4f770768ab133c7866b431b 386 SMART SM00382 38 219 1.8E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS01500 cef9702c198102580a3547398f95bfc4 484 SUPERFAMILY SSF75304 7 475 1.31E-114 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS01500 cef9702c198102580a3547398f95bfc4 484 Gene3D G3DSA:3.90.1300.10 11 478 9.5E-117 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS01500 cef9702c198102580a3547398f95bfc4 484 ProSitePatterns PS00571 Amidases signature. 151 182 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LK06_RS01500 cef9702c198102580a3547398f95bfc4 484 Pfam PF01425 Amidase 26 456 1.0E-102 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS32050 72de7be195051edf3fca48ba4330b6d2 252 SUPERFAMILY SSF53335 37 202 1.58E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS32050 72de7be195051edf3fca48ba4330b6d2 252 Gene3D G3DSA:3.40.50.150 32 249 3.0E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS32050 72de7be195051edf3fca48ba4330b6d2 252 Pfam PF13649 Methyltransferase domain 51 136 1.6E-12 T 06-07-2017 LK06_RS22560 1fca688569017ffb63f4d44f20222acd 250 SMART SM00382 26 223 8.0E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS22560 1fca688569017ffb63f4d44f20222acd 250 Pfam PF00005 ABC transporter 17 175 1.0E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS22560 1fca688569017ffb63f4d44f20222acd 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS22560 1fca688569017ffb63f4d44f20222acd 250 Gene3D G3DSA:3.40.50.300 1 247 1.2E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22560 1fca688569017ffb63f4d44f20222acd 250 PIRSF PIRSF039085 1 250 1.2E-123 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LK06_RS22560 1fca688569017ffb63f4d44f20222acd 250 SUPERFAMILY SSF52540 1 245 7.55E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27380 2e413d2ebd5c39d7859b22d10f0d5731 276 PIRSF PIRSF006241 4 276 4.8E-85 T 06-07-2017 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 LK06_RS27380 2e413d2ebd5c39d7859b22d10f0d5731 276 Pfam PF01261 Xylose isomerase-like TIM barrel 26 229 3.4E-27 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS27380 2e413d2ebd5c39d7859b22d10f0d5731 276 SUPERFAMILY SSF51658 9 270 1.66E-59 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS27380 2e413d2ebd5c39d7859b22d10f0d5731 276 Gene3D G3DSA:3.20.20.150 7 271 6.1E-72 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS30665 8433425dc6bde0027b190d176b714680 613 Pfam PF00733 Asparagine synthase 240 603 4.1E-80 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 LK06_RS30665 8433425dc6bde0027b190d176b714680 613 Gene3D G3DSA:3.60.20.10 1 223 2.2E-74 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS30665 8433425dc6bde0027b190d176b714680 613 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 538 7.4E-142 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 LK06_RS30665 8433425dc6bde0027b190d176b714680 613 Gene3D G3DSA:3.40.50.620 462 580 3.2E-71 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS30665 8433425dc6bde0027b190d176b714680 613 Gene3D G3DSA:3.40.50.620 224 400 3.2E-71 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS30665 8433425dc6bde0027b190d176b714680 613 PIRSF PIRSF001589 1 612 6.5E-132 T 06-07-2017 LK06_RS30665 8433425dc6bde0027b190d176b714680 613 SUPERFAMILY SSF56235 1 224 3.86E-63 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS30665 8433425dc6bde0027b190d176b714680 613 SUPERFAMILY SSF52402 458 579 1.7E-58 T 06-07-2017 LK06_RS30665 8433425dc6bde0027b190d176b714680 613 SUPERFAMILY SSF52402 228 396 1.7E-58 T 06-07-2017 LK06_RS30665 8433425dc6bde0027b190d176b714680 613 Pfam PF13537 Glutamine amidotransferase domain 48 169 3.8E-45 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 7.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 7.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 7.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 SUPERFAMILY SSF51735 7 247 1.05E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 247 8.3E-66 T 06-07-2017 LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.1E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.1E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.1E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.1E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.1E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.1E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 193 5.2E-5 T 06-07-2017 LK06_RS12820 e0fe56ceea37f6484e661c3e74605458 250 Gene3D G3DSA:3.40.50.720 7 247 4.4E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03385 ecc9652ea65f98dee33df3acbbdc1832 255 SMART SM00382 101 233 3.1E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS03385 ecc9652ea65f98dee33df3acbbdc1832 255 Pfam PF01695 IstB-like ATP binding protein 56 233 7.9E-72 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 LK06_RS03385 ecc9652ea65f98dee33df3acbbdc1832 255 Gene3D G3DSA:3.40.50.300 67 230 8.5E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03385 ecc9652ea65f98dee33df3acbbdc1832 255 SUPERFAMILY SSF52540 67 232 8.65E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03385 ecc9652ea65f98dee33df3acbbdc1832 255 PIRSF PIRSF003073 2 255 1.9E-85 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein LK06_RS26510 bcde0f81037c95f55b53032bc2b24d6b 509 SUPERFAMILY SSF47413 4 65 6.44E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS26510 bcde0f81037c95f55b53032bc2b24d6b 509 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 79 496 1.2E-39 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 LK06_RS26510 bcde0f81037c95f55b53032bc2b24d6b 509 Gene3D G3DSA:3.65.10.10 293 504 8.8E-38 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 LK06_RS26510 bcde0f81037c95f55b53032bc2b24d6b 509 Gene3D G3DSA:3.65.10.10 92 292 3.7E-39 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 LK06_RS26510 bcde0f81037c95f55b53032bc2b24d6b 509 Gene3D G3DSA:1.10.260.40 3 66 6.8E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS26510 bcde0f81037c95f55b53032bc2b24d6b 509 SMART SM00530 12 67 6.6E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS26510 bcde0f81037c95f55b53032bc2b24d6b 509 SUPERFAMILY SSF55205 74 506 7.03E-93 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 LK06_RS26510 bcde0f81037c95f55b53032bc2b24d6b 509 Pfam PF01381 Helix-turn-helix 13 63 2.8E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS25660 86efb7b4cacf2b89cfe12d3f96c74d6c 422 Gene3D G3DSA:3.40.640.10 66 281 8.2E-88 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS25660 86efb7b4cacf2b89cfe12d3f96c74d6c 422 TIGRFAM TIGR01821 5aminolev_synth: 5-aminolevulinic acid synthase 19 401 1.2E-161 T 06-07-2017 IPR010961 Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase GO:0003870|GO:0030170|GO:0033014 KEGG: 00260+2.3.1.37|KEGG: 00860+2.3.1.37|MetaCyc: PWY-5189|MetaCyc: PWY-7536|Reactome: R-HSA-189451 LK06_RS25660 86efb7b4cacf2b89cfe12d3f96c74d6c 422 SUPERFAMILY SSF53383 46 399 3.03E-107 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS25660 86efb7b4cacf2b89cfe12d3f96c74d6c 422 Pfam PF00155 Aminotransferase class I and II 48 391 7.5E-71 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS25660 86efb7b4cacf2b89cfe12d3f96c74d6c 422 Gene3D G3DSA:3.90.1150.10 282 396 4.5E-23 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS25660 86efb7b4cacf2b89cfe12d3f96c74d6c 422 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 245 254 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 LK06_RS29175 d986a97bc245ba7f762642448ebd9ff9 291 Pfam PF00486 Transcriptional regulatory protein, C terminal 43 108 7.8E-11 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS29175 d986a97bc245ba7f762642448ebd9ff9 291 SUPERFAMILY SSF46894 31 106 1.16E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS29175 d986a97bc245ba7f762642448ebd9ff9 291 SMART SM01043 132 277 7.4E-45 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS29175 d986a97bc245ba7f762642448ebd9ff9 291 Gene3D G3DSA:1.10.10.10 42 126 7.4E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29175 d986a97bc245ba7f762642448ebd9ff9 291 SMART SM00862 43 125 6.5E-11 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS29175 d986a97bc245ba7f762642448ebd9ff9 291 Pfam PF03704 Bacterial transcriptional activator domain 132 277 3.7E-40 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS29175 d986a97bc245ba7f762642448ebd9ff9 291 SUPERFAMILY SSF48452 130 287 8.91E-34 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS00315 9c5a26ceeed6937d6956f4907c612957 160 Pfam PF01750 Hydrogenase maturation protease 26 146 5.4E-10 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS00315 9c5a26ceeed6937d6956f4907c612957 160 Gene3D G3DSA:3.40.50.1450 6 153 3.8E-33 T 06-07-2017 IPR023430 Peptidase HybD-like domain LK06_RS00315 9c5a26ceeed6937d6956f4907c612957 160 PRINTS PR00446 Hydrogen uptake protein signature 58 68 1.2E-5 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS00315 9c5a26ceeed6937d6956f4907c612957 160 PRINTS PR00446 Hydrogen uptake protein signature 19 30 1.2E-5 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS00315 9c5a26ceeed6937d6956f4907c612957 160 PRINTS PR00446 Hydrogen uptake protein signature 7 19 1.2E-5 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS00315 9c5a26ceeed6937d6956f4907c612957 160 SUPERFAMILY SSF53163 6 149 4.97E-31 T 06-07-2017 IPR023430 Peptidase HybD-like domain LK06_RS00315 9c5a26ceeed6937d6956f4907c612957 160 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 8 148 3.3E-32 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS02115 299e5a47b7c42b1f8e05bd4f347270ef 386 SUPERFAMILY SSF51905 321 379 2.4E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02115 299e5a47b7c42b1f8e05bd4f347270ef 386 SUPERFAMILY SSF51905 6 219 2.4E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02115 299e5a47b7c42b1f8e05bd4f347270ef 386 Gene3D G3DSA:3.30.9.10 89 141 4.8E-12 T 06-07-2017 LK06_RS02115 299e5a47b7c42b1f8e05bd4f347270ef 386 Gene3D G3DSA:3.30.9.10 219 319 4.8E-12 T 06-07-2017 LK06_RS02115 299e5a47b7c42b1f8e05bd4f347270ef 386 Gene3D G3DSA:3.50.50.60 5 84 2.1E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02115 299e5a47b7c42b1f8e05bd4f347270ef 386 Gene3D G3DSA:3.50.50.60 142 218 2.1E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02115 299e5a47b7c42b1f8e05bd4f347270ef 386 Gene3D G3DSA:3.50.50.60 321 379 2.1E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02115 299e5a47b7c42b1f8e05bd4f347270ef 386 Pfam PF01266 FAD dependent oxidoreductase 8 359 8.2E-59 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS02115 299e5a47b7c42b1f8e05bd4f347270ef 386 SUPERFAMILY SSF54373 219 321 9.16E-11 T 06-07-2017 LK06_RS23060 8fccb8a73c1648559e2bb83df28f05aa 365 SUPERFAMILY SSF53955 57 206 3.19E-30 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS23060 8fccb8a73c1648559e2bb83df28f05aa 365 Pfam PF00877 NlpC/P60 family 244 350 5.2E-19 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS23060 8fccb8a73c1648559e2bb83df28f05aa 365 Gene3D G3DSA:1.10.530.10 58 207 1.3E-28 T 06-07-2017 LK06_RS23060 8fccb8a73c1648559e2bb83df28f05aa 365 SUPERFAMILY SSF54001 227 364 3.19E-31 T 06-07-2017 LK06_RS23060 8fccb8a73c1648559e2bb83df28f05aa 365 Gene3D G3DSA:3.90.1720.10 225 364 6.9E-34 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS23060 8fccb8a73c1648559e2bb83df28f05aa 365 Pfam PF01464 Transglycosylase SLT domain 68 176 5.0E-12 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 LK06_RS12770 463f5f20004f004ff69e75c3cf0361ba 405 SUPERFAMILY SSF56529 111 403 3.92E-87 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS12770 463f5f20004f004ff69e75c3cf0361ba 405 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 115 402 2.5E-52 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS12770 463f5f20004f004ff69e75c3cf0361ba 405 Gene3D G3DSA:2.30.30.230 5 111 1.8E-27 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 LK06_RS12770 463f5f20004f004ff69e75c3cf0361ba 405 Gene3D G3DSA:3.90.850.10 112 398 1.1E-103 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS12770 463f5f20004f004ff69e75c3cf0361ba 405 Pfam PF09298 Fumarylacetoacetase N-terminal 15 109 1.2E-18 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 LK06_RS12770 463f5f20004f004ff69e75c3cf0361ba 405 SUPERFAMILY SSF63433 5 109 9.29E-25 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 LK06_RS12770 463f5f20004f004ff69e75c3cf0361ba 405 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 6 403 4.3E-127 T 06-07-2017 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 LK06_RS23240 2c35e690db2ffaeee9da879236aa0570 355 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 353 2.3E-151 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 LK06_RS23240 2c35e690db2ffaeee9da879236aa0570 355 Gene3D G3DSA:1.20.58.410 5 87 3.3E-16 T 06-07-2017 LK06_RS23240 2c35e690db2ffaeee9da879236aa0570 355 Pfam PF00472 RF-1 domain 211 320 3.8E-41 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LK06_RS23240 2c35e690db2ffaeee9da879236aa0570 355 SUPERFAMILY SSF75620 8 352 3.92E-129 T 06-07-2017 LK06_RS23240 2c35e690db2ffaeee9da879236aa0570 355 SMART SM00937 63 178 4.1E-55 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 LK06_RS23240 2c35e690db2ffaeee9da879236aa0570 355 Gene3D G3DSA:3.30.160.20 210 288 1.1E-34 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain LK06_RS23240 2c35e690db2ffaeee9da879236aa0570 355 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 227 243 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LK06_RS23240 2c35e690db2ffaeee9da879236aa0570 355 Pfam PF03462 PCRF domain 9 203 2.5E-68 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 LK06_RS23240 2c35e690db2ffaeee9da879236aa0570 355 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 38.019 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 Hamap MF_00318 Enolase [eno]. 4 411 45.175 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 ProSitePatterns PS00164 Enolase signature. 334 347 - T 06-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 Gene3D G3DSA:3.30.390.10 6 127 3.0E-52 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 SUPERFAMILY SSF54826 6 140 3.38E-52 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 SMART SM01192 141 425 1.2E-228 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 SMART SM01193 6 136 2.2E-85 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 PRINTS PR00148 Enolase signature 163 176 6.3E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 PRINTS PR00148 Enolase signature 311 322 6.3E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 PRINTS PR00148 Enolase signature 334 348 6.3E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 PRINTS PR00148 Enolase signature 109 125 6.3E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 PRINTS PR00148 Enolase signature 363 380 6.3E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 PRINTS PR00148 Enolase signature 39 53 6.3E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 Pfam PF03952 Enolase, N-terminal domain 6 136 2.2E-55 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 PIRSF PIRSF001400 3 424 9.5E-188 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 SUPERFAMILY SSF51604 140 424 3.54E-133 T 06-07-2017 IPR029065 Enolase C-terminal domain-like LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 Gene3D G3DSA:3.20.20.120 130 424 9.6E-139 T 06-07-2017 IPR029065 Enolase C-terminal domain-like LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 6 425 8.2E-205 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19945 64701b27ca6417cab619f8b0fb138982 435 Pfam PF00113 Enolase, C-terminal TIM barrel domain 142 422 1.2E-133 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS01340 0e3478737d865dfeaac9c008ea69b0e5 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01340 0e3478737d865dfeaac9c008ea69b0e5 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01340 0e3478737d865dfeaac9c008ea69b0e5 192 SUPERFAMILY SSF46689 10 74 1.8E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01340 0e3478737d865dfeaac9c008ea69b0e5 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 3.7E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01340 0e3478737d865dfeaac9c008ea69b0e5 192 Gene3D G3DSA:1.10.357.10 56 182 2.0E-6 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS01340 0e3478737d865dfeaac9c008ea69b0e5 192 Gene3D G3DSA:1.10.10.60 10 55 5.1E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS04155 e3dc7d7fac1716c2c2d4bd31e11a36d6 368 Gene3D G3DSA:3.90.230.10 138 365 2.3E-56 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS04155 e3dc7d7fac1716c2c2d4bd31e11a36d6 368 SUPERFAMILY SSF53092 5 136 4.53E-15 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal LK06_RS04155 e3dc7d7fac1716c2c2d4bd31e11a36d6 368 Gene3D G3DSA:3.40.350.10 3 136 4.0E-12 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal LK06_RS04155 e3dc7d7fac1716c2c2d4bd31e11a36d6 368 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 138 9.8E-11 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 LK06_RS04155 e3dc7d7fac1716c2c2d4bd31e11a36d6 368 SUPERFAMILY SSF55920 138 366 4.45E-57 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS04155 e3dc7d7fac1716c2c2d4bd31e11a36d6 368 Pfam PF00557 Metallopeptidase family M24 146 348 2.3E-44 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS05655 ba566efcc90c666cc68f9147b6bd2206 120 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 118 1.8E-48 T 06-07-2017 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS05655 ba566efcc90c666cc68f9147b6bd2206 120 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 118 3.0E-50 T 06-07-2017 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS05655 ba566efcc90c666cc68f9147b6bd2206 120 PIRSF PIRSF005965 1 120 3.4E-42 T 06-07-2017 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS05655 ba566efcc90c666cc68f9147b6bd2206 120 SUPERFAMILY SSF55298 2 118 6.44E-40 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS05655 ba566efcc90c666cc68f9147b6bd2206 120 Pfam PF07736 Chorismate mutase type I 3 118 3.8E-41 T 06-07-2017 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS05655 ba566efcc90c666cc68f9147b6bd2206 120 Gene3D G3DSA:3.30.1330.40 3 119 1.7E-44 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS12250 ce03bffac57297568d270b47503b5b39 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 06-07-2017 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12250 ce03bffac57297568d270b47503b5b39 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 1.4E-24 T 06-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12250 ce03bffac57297568d270b47503b5b39 61 Gene3D G3DSA:4.10.830.10 1 61 7.7E-28 T 06-07-2017 LK06_RS12250 ce03bffac57297568d270b47503b5b39 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.974 T 06-07-2017 IPR023053 Ribosomal protein S14, type Z LK06_RS12250 ce03bffac57297568d270b47503b5b39 61 SUPERFAMILY SSF57716 4 61 1.43E-21 T 06-07-2017 LK06_RS00425 48beb2363e102803eb8171ac5a7388a0 81 Gene3D G3DSA:1.10.1200.10 5 79 9.1E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS00425 48beb2363e102803eb8171ac5a7388a0 81 Pfam PF00550 Phosphopantetheine attachment site 13 76 3.0E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS00425 48beb2363e102803eb8171ac5a7388a0 81 SUPERFAMILY SSF47336 2 79 1.31E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS06680 4e6a452e479021c2e1c897e63dd4d590 157 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 23 148 2.0E-54 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS06680 4e6a452e479021c2e1c897e63dd4d590 157 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 157 67.416 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS06680 4e6a452e479021c2e1c897e63dd4d590 157 PIRSF PIRSF001399 6 152 3.3E-59 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS06680 4e6a452e479021c2e1c897e63dd4d590 157 ProSitePatterns PS01029 Dehydroquinase class II signature. 13 30 - T 06-07-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS06680 4e6a452e479021c2e1c897e63dd4d590 157 SUPERFAMILY SSF52304 7 149 3.27E-59 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS06680 4e6a452e479021c2e1c897e63dd4d590 157 Gene3D G3DSA:3.40.50.9100 10 150 3.1E-61 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS06680 4e6a452e479021c2e1c897e63dd4d590 157 Pfam PF01220 Dehydroquinase class II 10 146 2.2E-56 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS06680 4e6a452e479021c2e1c897e63dd4d590 157 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 10 147 5.8E-53 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Gene3D G3DSA:1.10.10.400 264 335 1.6E-24 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 SUPERFAMILY SSF54211 321 492 9.62E-42 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 SMART SM00322 579 644 3.8E-10 T 06-07-2017 IPR004087 K Homology domain GO:0003676 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Gene3D G3DSA:2.40.50.140 653 720 1.1E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Gene3D G3DSA:3.30.1370.10 578 652 1.1E-23 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Pfam PF00575 S1 RNA binding domain 648 718 6.7E-13 T 06-07-2017 IPR003029 S1 domain GO:0003676 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 PIRSF PIRSF005499 7 741 4.7E-284 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 17 720 2.4E-262 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Gene3D G3DSA:3.30.230.70 8 249 5.2E-86 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Gene3D G3DSA:3.30.230.70 336 570 1.1E-80 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 722 0.0 T 06-07-2017 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 SUPERFAMILY SSF55666 474 573 8.74E-25 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 SUPERFAMILY SSF54791 576 688 2.51E-19 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 SMART SM00316 649 723 2.3E-17 T 06-07-2017 IPR022967 RNA-binding domain, S1 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 SUPERFAMILY SSF46915 265 344 3.14E-17 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 SUPERFAMILY SSF54211 6 151 1.21E-46 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 267 343 1.9E-17 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Pfam PF00013 KH domain 583 639 1.3E-10 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 SUPERFAMILY SSF55666 152 260 1.62E-29 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 9 726 27.102 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Pfam PF01138 3' exoribonuclease family, domain 1 348 480 9.1E-14 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LK06_RS24880 fcbc35427df208415e0f67ebd891722d 741 Pfam PF01138 3' exoribonuclease family, domain 1 20 151 6.8E-19 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LK06_RS07345 b52c094180b92c851c7f14be767e0ec4 203 Gene3D G3DSA:3.40.1050.10 42 201 1.2E-32 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS07345 b52c094180b92c851c7f14be767e0ec4 203 SUPERFAMILY SSF53056 22 201 7.46E-35 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS07345 b52c094180b92c851c7f14be767e0ec4 203 SMART SM00947 63 201 2.1E-24 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS07345 b52c094180b92c851c7f14be767e0ec4 203 Pfam PF00484 Carbonic anhydrase 71 168 2.1E-11 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS04930 b44211683ba8fbdd2c47383b622092b3 206 Gene3D G3DSA:3.40.50.300 22 193 3.8E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04930 b44211683ba8fbdd2c47383b622092b3 206 SUPERFAMILY SSF52540 25 196 3.56E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04930 b44211683ba8fbdd2c47383b622092b3 206 PRINTS PR00449 Transforming protein P21 ras signature 84 106 1.3E-5 T 06-07-2017 LK06_RS04930 b44211683ba8fbdd2c47383b622092b3 206 PRINTS PR00449 Transforming protein P21 ras signature 174 196 1.3E-5 T 06-07-2017 LK06_RS04930 b44211683ba8fbdd2c47383b622092b3 206 PRINTS PR00449 Transforming protein P21 ras signature 26 47 1.3E-5 T 06-07-2017 LK06_RS04930 b44211683ba8fbdd2c47383b622092b3 206 Pfam PF03029 Conserved hypothetical ATP binding protein 30 152 4.4E-23 T 06-07-2017 IPR004130 GPN-loop GTPase LK06_RS05110 971b6f25f0986de8e03ac536d03ecbaf 512 Gene3D G3DSA:3.30.420.40 264 509 2.4E-98 T 06-07-2017 LK06_RS05110 971b6f25f0986de8e03ac536d03ecbaf 512 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 373 393 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LK06_RS05110 971b6f25f0986de8e03ac536d03ecbaf 512 PIRSF PIRSF000538 9 512 4.2E-166 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LK06_RS05110 971b6f25f0986de8e03ac536d03ecbaf 512 Hamap MF_00186 Glycerol kinase [glpK]. 8 508 55.272 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 LK06_RS05110 971b6f25f0986de8e03ac536d03ecbaf 512 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 9 507 1.8E-223 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 LK06_RS05110 971b6f25f0986de8e03ac536d03ecbaf 512 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 272 461 3.0E-58 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 LK06_RS05110 971b6f25f0986de8e03ac536d03ecbaf 512 SUPERFAMILY SSF53067 10 265 6.65E-94 T 06-07-2017 LK06_RS05110 971b6f25f0986de8e03ac536d03ecbaf 512 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 11 262 6.7E-82 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 LK06_RS05110 971b6f25f0986de8e03ac536d03ecbaf 512 Gene3D G3DSA:3.30.420.40 7 263 9.6E-109 T 06-07-2017 LK06_RS05110 971b6f25f0986de8e03ac536d03ecbaf 512 SUPERFAMILY SSF53067 264 508 1.34E-79 T 06-07-2017 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 SUPERFAMILY SSF56059 114 322 3.18E-57 T 06-07-2017 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 4.2E-73 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 Gene3D G3DSA:3.30.470.20 203 450 2.2E-88 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 4.0E-44 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 Gene3D G3DSA:2.40.50.100 520 590 6.1E-21 T 06-07-2017 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 SUPERFAMILY SSF51246 328 435 8.37E-37 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 SMART SM00878 333 447 2.6E-55 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 SUPERFAMILY SSF52440 2 112 6.69E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 Gene3D G3DSA:3.30.1490.20 129 201 3.9E-21 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 546 563 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 Gene3D G3DSA:3.40.50.20 2 128 1.8E-49 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 SUPERFAMILY SSF51230 519 589 2.22E-18 T 06-07-2017 IPR011053 Single hybrid motif LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 Pfam PF00364 Biotin-requiring enzyme 523 589 4.3E-16 T 06-07-2017 IPR000089 Biotin/lipoyl attachment LK06_RS20835 2f4bfc2e7cfb6c78254f5333e6a721a3 591 Pfam PF02785 Biotin carboxylase C-terminal domain 333 447 1.2E-35 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS02070 81d0529db5c961327056533b4a8fbf3a 739 Gene3D G3DSA:3.40.718.10 186 284 3.1E-32 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LK06_RS02070 81d0529db5c961327056533b4a8fbf3a 739 Gene3D G3DSA:3.40.718.10 536 643 3.1E-32 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LK06_RS02070 81d0529db5c961327056533b4a8fbf3a 739 Gene3D G3DSA:3.40.718.10 337 360 3.1E-32 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LK06_RS02070 81d0529db5c961327056533b4a8fbf3a 739 PIRSF PIRSF009407 1 739 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 LK06_RS02070 81d0529db5c961327056533b4a8fbf3a 739 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 3 738 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 LK06_RS02070 81d0529db5c961327056533b4a8fbf3a 739 SUPERFAMILY SSF53659 4 738 0.0 T 06-07-2017 LK06_RS02070 81d0529db5c961327056533b4a8fbf3a 739 Pfam PF03971 Monomeric isocitrate dehydrogenase 5 735 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 LK06_RS25435 0f75311e74fda49a45f08f532f60a0df 439 SUPERFAMILY SSF56176 11 188 1.54E-46 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS25435 0f75311e74fda49a45f08f532f60a0df 439 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 23 56 - T 06-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 LK06_RS25435 0f75311e74fda49a45f08f532f60a0df 439 Gene3D G3DSA:3.30.465.10 81 188 8.4E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS25435 0f75311e74fda49a45f08f532f60a0df 439 Pfam PF04030 D-arabinono-1,4-lactone oxidase 182 436 3.8E-79 T 06-07-2017 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 LK06_RS25435 0f75311e74fda49a45f08f532f60a0df 439 Gene3D G3DSA:3.30.43.10 11 80 1.4E-23 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS25435 0f75311e74fda49a45f08f532f60a0df 439 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 12 438 3.9E-117 T 06-07-2017 LK06_RS25435 0f75311e74fda49a45f08f532f60a0df 439 Pfam PF01565 FAD binding domain 23 158 1.5E-32 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LK06_RS25435 0f75311e74fda49a45f08f532f60a0df 439 PIRSF PIRSF000136 2 439 1.4E-114 T 06-07-2017 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 LK06_RS14845 a1d9434f2a700e185b1e3e41e96b0901 346 Gene3D G3DSA:2.60.40.10 46 103 3.9E-6 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS28750 35485c62e020694540c6539fc5551e49 343 Pfam PF11946 Domain of unknown function (DUF3463) 196 328 2.8E-56 T 06-07-2017 IPR022563 Domain of unknown function DUF3463 LK06_RS28750 35485c62e020694540c6539fc5551e49 343 SUPERFAMILY SSF102114 23 308 3.53E-48 T 06-07-2017 LK06_RS28750 35485c62e020694540c6539fc5551e49 343 Pfam PF04055 Radical SAM superfamily 34 187 3.0E-17 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS28750 35485c62e020694540c6539fc5551e49 343 Gene3D G3DSA:3.20.20.70 19 310 5.4E-41 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS28750 35485c62e020694540c6539fc5551e49 343 Pfam PF13394 4Fe-4S single cluster domain 37 112 8.3E-5 T 06-07-2017 LK06_RS28750 35485c62e020694540c6539fc5551e49 343 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 318 7.3E-162 T 06-07-2017 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH LK06_RS17465 f97c5a7e3aec86f038b1cbf36d49313f 87 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS17465 f97c5a7e3aec86f038b1cbf36d49313f 87 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS17465 f97c5a7e3aec86f038b1cbf36d49313f 87 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS17465 f97c5a7e3aec86f038b1cbf36d49313f 87 Gene3D G3DSA:1.10.10.10 1 83 2.5E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17465 f97c5a7e3aec86f038b1cbf36d49313f 87 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.7E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS17465 f97c5a7e3aec86f038b1cbf36d49313f 87 SUPERFAMILY SSF46785 1 84 9.98E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS10445 da76ad4e6794b35af3235b8fd78bd5db 628 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 200 1.7E-35 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LK06_RS10445 da76ad4e6794b35af3235b8fd78bd5db 628 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 7 625 4.1E-268 T 06-07-2017 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 LK06_RS10445 da76ad4e6794b35af3235b8fd78bd5db 628 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 223 355 9.6E-32 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LK06_RS10445 da76ad4e6794b35af3235b8fd78bd5db 628 SUPERFAMILY SSF52518 4 212 2.04E-31 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS10445 da76ad4e6794b35af3235b8fd78bd5db 628 SUPERFAMILY SSF52518 400 617 1.01E-47 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS10445 da76ad4e6794b35af3235b8fd78bd5db 628 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 579 2.0E-38 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LK06_RS10445 da76ad4e6794b35af3235b8fd78bd5db 628 Gene3D G3DSA:3.40.50.1220 213 362 5.4E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS10445 da76ad4e6794b35af3235b8fd78bd5db 628 SUPERFAMILY SSF52467 188 375 1.31E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS10445 da76ad4e6794b35af3235b8fd78bd5db 628 Gene3D G3DSA:3.40.50.970 2 212 1.4E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS10445 da76ad4e6794b35af3235b8fd78bd5db 628 Gene3D G3DSA:3.40.50.970 396 620 9.9E-55 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 SUPERFAMILY SSF48179 522 615 1.11E-17 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 SUPERFAMILY SSF52096 253 327 3.94E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 SUPERFAMILY SSF52096 34 220 3.94E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 Gene3D G3DSA:1.10.1040.10 526 611 3.6E-11 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 Pfam PF00378 Enoyl-CoA hydratase/isomerase 53 235 1.5E-18 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 SUPERFAMILY SSF51735 338 522 8.05E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 Gene3D G3DSA:3.90.226.10 35 237 1.5E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 Gene3D G3DSA:3.40.50.720 334 525 4.5E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 524 606 8.8E-12 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 SUPERFAMILY SSF48179 634 700 2.04E-10 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS26595 aded173eb12dd94f39af69c4844f2119 709 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 340 520 7.5E-58 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS20285 6216069b8a3d5ab8bb88bd4d21cefabc 826 Gene3D G3DSA:1.10.10.160 177 251 8.0E-26 T 06-07-2017 IPR013986 DExx box DNA helicase domain LK06_RS20285 6216069b8a3d5ab8bb88bd4d21cefabc 826 Gene3D G3DSA:3.40.50.300 365 467 3.2E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20285 6216069b8a3d5ab8bb88bd4d21cefabc 826 Gene3D G3DSA:3.40.50.300 636 725 3.2E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20285 6216069b8a3d5ab8bb88bd4d21cefabc 826 SUPERFAMILY SSF52540 69 723 1.84E-178 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20285 6216069b8a3d5ab8bb88bd4d21cefabc 826 Pfam PF00580 UvrD/REP helicase N-terminal domain 73 350 5.0E-78 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 LK06_RS20285 6216069b8a3d5ab8bb88bd4d21cefabc 826 Gene3D G3DSA:1.10.486.10 468 622 5.7E-48 T 06-07-2017 LK06_RS20285 6216069b8a3d5ab8bb88bd4d21cefabc 826 Gene3D G3DSA:3.40.50.300 69 173 5.9E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20285 6216069b8a3d5ab8bb88bd4d21cefabc 826 Gene3D G3DSA:3.40.50.300 252 364 5.9E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20285 6216069b8a3d5ab8bb88bd4d21cefabc 826 Pfam PF13361 UvrD-like helicase C-terminal domain 356 698 1.0E-68 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 LK06_RS20285 6216069b8a3d5ab8bb88bd4d21cefabc 826 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 69 824 0.0 T 06-07-2017 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 LK06_RS28930 55e011bc575af5c151856c9795606354 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 393 5.9E-141 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS28930 55e011bc575af5c151856c9795606354 395 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 LK06_RS28930 55e011bc575af5c151856c9795606354 395 Gene3D G3DSA:3.40.47.10 6 125 5.7E-68 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28930 55e011bc575af5c151856c9795606354 395 Gene3D G3DSA:3.40.47.10 200 277 5.7E-68 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28930 55e011bc575af5c151856c9795606354 395 SUPERFAMILY SSF53901 6 272 1.23E-81 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28930 55e011bc575af5c151856c9795606354 395 SUPERFAMILY SSF53901 275 394 8.64E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28930 55e011bc575af5c151856c9795606354 395 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 LK06_RS28930 55e011bc575af5c151856c9795606354 395 Pfam PF00108 Thiolase, N-terminal domain 7 265 1.8E-78 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 LK06_RS28930 55e011bc575af5c151856c9795606354 395 Pfam PF02803 Thiolase, C-terminal domain 274 394 2.3E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 LK06_RS28930 55e011bc575af5c151856c9795606354 395 PIRSF PIRSF000429 2 395 3.0E-138 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS28930 55e011bc575af5c151856c9795606354 395 Gene3D G3DSA:3.40.47.10 279 394 2.1E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28930 55e011bc575af5c151856c9795606354 395 Gene3D G3DSA:3.40.47.10 151 199 2.1E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28930 55e011bc575af5c151856c9795606354 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 LK06_RS01875 636c408239c60304aa9e9bbf22a387eb 207 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 44 199 1.7E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01875 636c408239c60304aa9e9bbf22a387eb 207 SUPERFAMILY SSF88659 140 200 6.73E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01875 636c408239c60304aa9e9bbf22a387eb 207 Pfam PF04545 Sigma-70, region 4 148 196 1.4E-13 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01875 636c408239c60304aa9e9bbf22a387eb 207 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 68 100 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01875 636c408239c60304aa9e9bbf22a387eb 207 Pfam PF04542 Sigma-70 region 2 48 114 1.0E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01875 636c408239c60304aa9e9bbf22a387eb 207 SUPERFAMILY SSF88946 43 127 9.02E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01875 636c408239c60304aa9e9bbf22a387eb 207 Gene3D G3DSA:1.10.10.10 140 201 6.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01875 636c408239c60304aa9e9bbf22a387eb 207 Gene3D G3DSA:1.10.1740.10 42 134 1.5E-20 T 06-07-2017 LK06_RS14790 8a8cee66c1e2ef9bdbe038c61cdba9cd 169 Pfam PF00156 Phosphoribosyl transferase domain 13 151 2.1E-22 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 LK06_RS14790 8a8cee66c1e2ef9bdbe038c61cdba9cd 169 Gene3D G3DSA:3.40.50.2020 9 153 1.7E-32 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS14790 8a8cee66c1e2ef9bdbe038c61cdba9cd 169 SUPERFAMILY SSF53271 8 151 1.18E-25 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 SUPERFAMILY SSF52172 3 137 5.41E-36 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 2.8E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 Gene3D G3DSA:1.10.10.10 126 220 5.3E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 SUPERFAMILY SSF46894 144 218 2.28E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 SMART SM00448 3 118 1.7E-37 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 Pfam PF00072 Response regulator receiver domain 5 119 7.4E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 SMART SM00421 155 212 1.3E-28 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 Gene3D G3DSA:3.40.50.2300 3 125 4.3E-40 T 06-07-2017 LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 4.7E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 4.7E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05075 56ebd7b4ac88828325eee3cfa43a28f5 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 4.7E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20655 4c715312a2224bfbe5055d7bed107ff9 590 PRINTS PR01806 Virulence factor MviN signature 87 106 9.3E-17 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS20655 4c715312a2224bfbe5055d7bed107ff9 590 PRINTS PR01806 Virulence factor MviN signature 183 207 9.3E-17 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS20655 4c715312a2224bfbe5055d7bed107ff9 590 PRINTS PR01806 Virulence factor MviN signature 424 443 9.3E-17 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS20655 4c715312a2224bfbe5055d7bed107ff9 590 PRINTS PR01806 Virulence factor MviN signature 106 122 9.3E-17 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS20655 4c715312a2224bfbe5055d7bed107ff9 590 PRINTS PR01806 Virulence factor MviN signature 207 228 9.3E-17 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS20655 4c715312a2224bfbe5055d7bed107ff9 590 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 57 575 5.2E-100 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS20655 4c715312a2224bfbe5055d7bed107ff9 590 Pfam PF03023 MviN-like protein 82 524 8.2E-94 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS16615 713c8ef0a494d56ae5f7b936ecc57cbd 269 Pfam PF00072 Response regulator receiver domain 45 154 2.2E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS16615 713c8ef0a494d56ae5f7b936ecc57cbd 269 Gene3D G3DSA:1.10.10.10 167 265 5.5E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16615 713c8ef0a494d56ae5f7b936ecc57cbd 269 Gene3D G3DSA:3.40.50.2300 36 162 5.8E-40 T 06-07-2017 LK06_RS16615 713c8ef0a494d56ae5f7b936ecc57cbd 269 SUPERFAMILY SSF46894 167 264 1.5E-28 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS16615 713c8ef0a494d56ae5f7b936ecc57cbd 269 Pfam PF00486 Transcriptional regulatory protein, C terminal 190 263 7.4E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS16615 713c8ef0a494d56ae5f7b936ecc57cbd 269 SUPERFAMILY SSF52172 39 165 9.53E-41 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS16615 713c8ef0a494d56ae5f7b936ecc57cbd 269 SMART SM00448 43 154 1.7E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS16615 713c8ef0a494d56ae5f7b936ecc57cbd 269 SMART SM00862 190 264 2.8E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS01655 f9953c722a1589da45e7f1c30c6c2fc0 474 PIRSF PIRSF006060 12 471 1.7E-92 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS01655 f9953c722a1589da45e7f1c30c6c2fc0 474 Pfam PF13520 Amino acid permease 34 440 6.3E-58 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS01155 60368d6c06c8176f696837ed3cca985b 189 SUPERFAMILY SSF46689 5 61 1.95E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01155 60368d6c06c8176f696837ed3cca985b 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 56 1.3E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01155 60368d6c06c8176f696837ed3cca985b 189 Gene3D G3DSA:1.10.357.10 8 188 4.3E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS01155 60368d6c06c8176f696837ed3cca985b 189 SUPERFAMILY SSF48498 73 186 4.13E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS01155 60368d6c06c8176f696837ed3cca985b 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 4.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01155 60368d6c06c8176f696837ed3cca985b 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 4.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01155 60368d6c06c8176f696837ed3cca985b 189 Pfam PF16859 Bacterial transcriptional repressor C-terminal 72 154 2.5E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS18970 fd0430470350b813326527e212e8d49f 312 SUPERFAMILY SSF51679 27 311 2.09E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS18970 fd0430470350b813326527e212e8d49f 312 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 38 286 9.2E-67 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted LK06_RS18970 fd0430470350b813326527e212e8d49f 312 Gene3D G3DSA:3.20.20.30 8 311 9.8E-70 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS18970 fd0430470350b813326527e212e8d49f 312 Pfam PF00296 Luciferase-like monooxygenase 19 243 1.3E-49 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 Gene3D G3DSA:1.20.210.10 26 549 5.0E-190 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 41 484 1.2E-142 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 SUPERFAMILY SSF81442 29 539 3.14E-173 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 105 129 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 390 409 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 238 259 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 148 160 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 440 461 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 180 198 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 259 280 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 31 56 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 78 101 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 327 348 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 362 380 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 305 320 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 209 228 2.5E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 536 6.4E-212 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 LK06_RS00520 ac0d023df43a2da0704e0823b623e951 562 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 261 315 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS18450 45eae48e4bb808e0f2c0eddb76d3b724 215 Gene3D G3DSA:3.40.50.1000 75 203 2.0E-23 T 06-07-2017 IPR023214 HAD-like domain LK06_RS18450 45eae48e4bb808e0f2c0eddb76d3b724 215 Gene3D G3DSA:1.10.150.240 22 74 1.6E-9 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 LK06_RS18450 45eae48e4bb808e0f2c0eddb76d3b724 215 Pfam PF12710 haloacid dehalogenase-like hydrolase 12 164 1.9E-13 T 06-07-2017 LK06_RS18450 45eae48e4bb808e0f2c0eddb76d3b724 215 SUPERFAMILY SSF56784 11 203 8.83E-35 T 06-07-2017 IPR023214 HAD-like domain LK06_RS21150 521a06491db88d166c4b5032c5fe75a6 478 SUPERFAMILY SSF52096 147 470 3.98E-41 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS21150 521a06491db88d166c4b5032c5fe75a6 478 Pfam PF03572 Peptidase family S41 265 454 7.1E-26 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LK06_RS21150 521a06491db88d166c4b5032c5fe75a6 478 Gene3D G3DSA:3.30.750.44 144 212 1.8E-10 T 06-07-2017 LK06_RS21150 521a06491db88d166c4b5032c5fe75a6 478 SMART SM00245 227 455 2.0E-6 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LK06_RS21150 521a06491db88d166c4b5032c5fe75a6 478 Pfam PF14684 Tricorn protease C1 domain 149 213 1.1E-9 T 06-07-2017 IPR028204 Tricorn protease C1 domain LK06_RS21150 521a06491db88d166c4b5032c5fe75a6 478 Gene3D G3DSA:3.90.226.10 261 477 2.7E-31 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS28790 40f439f177c25f464b95327105b8c560 303 Gene3D G3DSA:2.70.70.10 156 297 3.9E-43 T 06-07-2017 LK06_RS28790 40f439f177c25f464b95327105b8c560 303 Pfam PF01551 Peptidase family M23 194 291 1.8E-32 T 06-07-2017 IPR016047 Peptidase M23 LK06_RS28790 40f439f177c25f464b95327105b8c560 303 SUPERFAMILY SSF51261 157 295 2.25E-43 T 06-07-2017 IPR011055 Duplicated hybrid motif LK06_RS28790 40f439f177c25f464b95327105b8c560 303 Gene3D G3DSA:3.10.350.10 71 120 1.1E-5 T 06-07-2017 IPR018392 LysM domain LK06_RS20675 5debb15500ed34be4dde55bfa78ee5cc 396 Pfam PF01546 Peptidase family M20/M25/M40 73 385 1.9E-26 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 LK06_RS20675 5debb15500ed34be4dde55bfa78ee5cc 396 PIRSF PIRSF005962 1 392 1.0E-94 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 LK06_RS20675 5debb15500ed34be4dde55bfa78ee5cc 396 SUPERFAMILY SSF53187 302 387 3.25E-62 T 06-07-2017 LK06_RS20675 5debb15500ed34be4dde55bfa78ee5cc 396 SUPERFAMILY SSF53187 4 201 3.25E-62 T 06-07-2017 LK06_RS20675 5debb15500ed34be4dde55bfa78ee5cc 396 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 11 379 2.4E-100 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 LK06_RS20675 5debb15500ed34be4dde55bfa78ee5cc 396 Gene3D G3DSA:3.40.630.10 302 387 5.2E-86 T 06-07-2017 LK06_RS20675 5debb15500ed34be4dde55bfa78ee5cc 396 Gene3D G3DSA:3.40.630.10 4 182 5.2E-86 T 06-07-2017 LK06_RS20675 5debb15500ed34be4dde55bfa78ee5cc 396 Pfam PF07687 Peptidase dimerisation domain 191 283 1.3E-6 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS20675 5debb15500ed34be4dde55bfa78ee5cc 396 SUPERFAMILY SSF55031 187 300 1.03E-21 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS20675 5debb15500ed34be4dde55bfa78ee5cc 396 Gene3D G3DSA:3.30.70.360 186 301 1.7E-28 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 45 228 1.6E-61 T 06-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 41 526 86.247 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 218 224 - T 06-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 Gene3D G3DSA:3.40.50.720 41 227 7.5E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 SUPERFAMILY SSF55347 218 525 1.08E-111 T 06-07-2017 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 SUPERFAMILY SSF51735 30 231 8.27E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 PIRSF PIRSF000110 24 527 4.7E-177 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 278 294 4.2E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 208 236 4.2E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 367 393 4.2E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 184 197 4.2E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 260 277 4.2E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 Gene3D G3DSA:3.30.360.10 228 525 2.4E-120 T 06-07-2017 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 230 525 3.5E-113 T 06-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS28395 a196b13f3c0f7e580e21e1cadaa412c7 527 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 43 526 2.6E-198 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 Gene3D G3DSA:3.30.200.20 11 119 1.0E-15 T 06-07-2017 LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 SUPERFAMILY SSF56112 19 269 1.34E-65 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 SMART SM00564 622 653 30.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 SMART SM00564 410 441 98.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 SMART SM00564 450 483 35.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 SMART SM00564 661 693 0.013 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 SMART SM00564 489 521 25.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 SMART SM00564 531 568 2.2 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 Pfam PF00069 Protein kinase domain 22 269 5.2E-39 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 Gene3D G3DSA:2.140.10.10 396 490 4.1E-11 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 Gene3D G3DSA:2.140.10.10 621 730 4.0E-18 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 Gene3D G3DSA:2.140.10.10 493 609 9.1E-11 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 Gene3D G3DSA:1.10.510.10 120 339 1.9E-45 T 06-07-2017 LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 SUPERFAMILY SSF50998 432 730 3.92E-33 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 28 50 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 SMART SM00220 22 274 3.3E-47 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 Pfam PF13360 PQQ-like domain 593 734 2.6E-12 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat LK06_RS13555 e9901697a214c1a88c41e347cd60a04f 737 Pfam PF13360 PQQ-like domain 424 570 9.9E-21 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat LK06_RS29455 15d088be2e5b0307bfe1033353d43caf 379 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 17 368 32.85 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS29455 15d088be2e5b0307bfe1033353d43caf 379 Pfam PF04551 GcpE protein 23 362 3.0E-124 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS29455 15d088be2e5b0307bfe1033353d43caf 379 SUPERFAMILY SSF51717 47 218 1.88E-8 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS29455 15d088be2e5b0307bfe1033353d43caf 379 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 19 360 2.5E-120 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS29455 15d088be2e5b0307bfe1033353d43caf 379 PIRSF PIRSF004640 13 373 2.2E-133 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS29455 15d088be2e5b0307bfe1033353d43caf 379 SUPERFAMILY SSF56014 277 359 4.8E-13 T 06-07-2017 LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 9.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 9.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 SUPERFAMILY SSF51735 6 261 5.26E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 5.1E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.1E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 5.1E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 5.1E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 5.1E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 202 0.0065 T 06-07-2017 LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 Gene3D G3DSA:3.40.50.720 5 270 7.3E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06975 649261a182afe64e5734dc79df13cf9d 301 Pfam PF00106 short chain dehydrogenase 9 210 3.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 Gene3D G3DSA:3.40.50.10490 23 99 3.0E-67 T 06-07-2017 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 Gene3D G3DSA:3.40.50.10490 159 236 3.0E-67 T 06-07-2017 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 42.153 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 06-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 SUPERFAMILY SSF52313 6 227 1.83E-90 T 06-07-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 1.5E-106 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 Gene3D G3DSA:1.10.287.610 100 153 7.0E-21 T 06-07-2017 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 Pfam PF00318 Ribosomal protein S2 9 225 2.4E-95 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 PRINTS PR00395 Ribosomal protein S2 signature 159 176 8.0E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 PRINTS PR00395 Ribosomal protein S2 signature 87 104 8.0E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 PRINTS PR00395 Ribosomal protein S2 signature 176 187 8.0E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 PRINTS PR00395 Ribosomal protein S2 signature 37 46 8.0E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 PRINTS PR00395 Ribosomal protein S2 signature 6 24 8.0E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24495 5296e8c10c5a81f924250cc3e1911c6f 306 PRINTS PR00395 Ribosomal protein S2 signature 197 211 8.0E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS15345 bb12eab1cea28a7e724d4528da184c7a 274 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 244 4.0E-40 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type LK06_RS15345 bb12eab1cea28a7e724d4528da184c7a 274 Gene3D G3DSA:1.20.120.450 13 153 4.9E-7 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase LK06_RS15345 bb12eab1cea28a7e724d4528da184c7a 274 SUPERFAMILY SSF109854 4 159 1.99E-32 T 06-07-2017 LK06_RS15345 bb12eab1cea28a7e724d4528da184c7a 274 Pfam PF07398 MDMPI C-terminal domain 178 264 3.8E-10 T 06-07-2017 IPR010872 MDMPI C-terminal LK06_RS15345 bb12eab1cea28a7e724d4528da184c7a 274 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 153 2.6E-22 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 LK06_RS29805 5fa3baaf50bd1053be71f97d532939d5 159 SUPERFAMILY SSF54909 65 149 2.41E-20 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS29805 5fa3baaf50bd1053be71f97d532939d5 159 SMART SM00344 4 110 7.3E-30 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS29805 5fa3baaf50bd1053be71f97d532939d5 159 Gene3D G3DSA:3.30.70.920 57 148 5.2E-23 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS29805 5fa3baaf50bd1053be71f97d532939d5 159 SUPERFAMILY SSF46785 4 64 1.22E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29805 5fa3baaf50bd1053be71f97d532939d5 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.1E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS29805 5fa3baaf50bd1053be71f97d532939d5 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.1E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS29805 5fa3baaf50bd1053be71f97d532939d5 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.1E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS29805 5fa3baaf50bd1053be71f97d532939d5 159 Pfam PF01037 Lrp/AsnC ligand binding domain 70 140 4.7E-20 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS29805 5fa3baaf50bd1053be71f97d532939d5 159 Gene3D G3DSA:1.10.10.10 2 53 2.1E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29805 5fa3baaf50bd1053be71f97d532939d5 159 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 6.9E-14 T 06-07-2017 LK06_RS23680 ba743538d76649d0a2df1d74bc16d524 168 Gene3D G3DSA:1.10.1740.10 7 77 1.5E-8 T 06-07-2017 LK06_RS23680 ba743538d76649d0a2df1d74bc16d524 168 SUPERFAMILY SSF88946 7 89 1.45E-8 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS23680 ba743538d76649d0a2df1d74bc16d524 168 Gene3D G3DSA:1.10.10.10 102 162 1.7E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23680 ba743538d76649d0a2df1d74bc16d524 168 SUPERFAMILY SSF88659 102 160 6.17E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS23680 ba743538d76649d0a2df1d74bc16d524 168 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 161 2.6E-49 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 LK06_RS23680 ba743538d76649d0a2df1d74bc16d524 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 159 4.3E-16 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS23680 ba743538d76649d0a2df1d74bc16d524 168 Pfam PF04542 Sigma-70 region 2 20 79 2.6E-6 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS23680 ba743538d76649d0a2df1d74bc16d524 168 Pfam PF08281 Sigma-70, region 4 106 156 1.5E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 SUPERFAMILY SSF81606 352 552 2.09E-11 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 SMART SM00086 92 134 4.7E-7 T 06-07-2017 IPR001610 PAC motif LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 Gene3D G3DSA:3.30.450.20 27 131 4.3E-15 T 06-07-2017 LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 Gene3D G3DSA:3.30.565.10 593 686 4.4E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 SMART SM00065 166 319 0.0019 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 Gene3D G3DSA:3.30.450.40 150 323 3.5E-13 T 06-07-2017 IPR029016 GAF domain-like LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 366 553 2.4E-46 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 SUPERFAMILY SSF55785 26 133 1.74E-15 T 06-07-2017 IPR000014 PAS domain LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 Pfam PF13185 GAF domain 173 309 1.2E-9 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 SUPERFAMILY SSF55781 185 320 2.4E-14 T 06-07-2017 IPR029016 GAF domain-like LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 Gene3D G3DSA:3.60.40.10 478 551 3.4E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 Pfam PF13581 Histidine kinase-like ATPase domain 571 682 4.2E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 SMART SM00331 337 553 2.5E-32 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 Pfam PF08447 PAS fold 41 128 1.3E-14 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 68 134 5.3E-6 T 06-07-2017 IPR000014 PAS domain LK06_RS01685 d80b5f2c2af04586aa7a4ba119846136 688 SUPERFAMILY SSF55874 592 683 3.94E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 468 2.1E-199 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 06-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 SUPERFAMILY SSF54368 5 99 9.55E-29 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 256 271 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 Pfam PF00120 Glutamine synthetase, catalytic domain 102 466 6.2E-136 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 Gene3D G3DSA:3.10.20.70 5 104 5.3E-33 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 385 397 - T 06-07-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 SUPERFAMILY SSF55931 102 468 1.96E-137 T 06-07-2017 LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 SMART SM01230 101 378 1.0E-151 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 Gene3D G3DSA:3.30.590.10 105 448 2.2E-135 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LK06_RS07935 8278948580646d1e44c749bcf83ad3d1 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 94 7.0E-23 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS24920 e1d11ce5e9c0c2fe4eef30d6c40d74b3 561 Gene3D G3DSA:3.60.15.10 18 265 4.8E-76 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS24920 e1d11ce5e9c0c2fe4eef30d6c40d74b3 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 41.168 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 LK06_RS24920 e1d11ce5e9c0c2fe4eef30d6c40d74b3 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 6.0E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS24920 e1d11ce5e9c0c2fe4eef30d6c40d74b3 561 PIRSF PIRSF004803 14 561 2.4E-205 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 LK06_RS24920 e1d11ce5e9c0c2fe4eef30d6c40d74b3 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 411 9.8E-10 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain LK06_RS24920 e1d11ce5e9c0c2fe4eef30d6c40d74b3 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 558 5.9E-150 T 06-07-2017 IPR004613 Ribonuclease J GO:0003723|GO:0046872 LK06_RS24920 e1d11ce5e9c0c2fe4eef30d6c40d74b3 561 SMART SM00849 31 225 3.1E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS24920 e1d11ce5e9c0c2fe4eef30d6c40d74b3 561 SUPERFAMILY SSF56281 19 433 2.1E-94 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS12265 3f50ccf8806a6bca0e8002ce123e4350 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.009 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 LK06_RS12265 3f50ccf8806a6bca0e8002ce123e4350 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 7.8E-54 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 LK06_RS12265 3f50ccf8806a6bca0e8002ce123e4350 122 SMART SM01374 1 122 1.9E-87 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 LK06_RS12265 3f50ccf8806a6bca0e8002ce123e4350 122 SUPERFAMILY SSF50193 2 122 3.01E-50 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 LK06_RS12265 3f50ccf8806a6bca0e8002ce123e4350 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.1E-57 T 06-07-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 LK06_RS12265 3f50ccf8806a6bca0e8002ce123e4350 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 06-07-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12265 3f50ccf8806a6bca0e8002ce123e4350 122 Gene3D G3DSA:2.40.150.20 2 122 2.5E-53 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 LK06_RS22040 ace06431fc9075afba3a34e54e784aec 151 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 135 14.076 T 06-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 LK06_RS22040 ace06431fc9075afba3a34e54e784aec 151 Pfam PF02416 mttA/Hcf106 family 5 47 1.1E-6 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 LK06_RS22040 ace06431fc9075afba3a34e54e784aec 151 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 5.9E-9 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 LK06_RS22040 ace06431fc9075afba3a34e54e784aec 151 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 5.9E-9 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 LK06_RS22040 ace06431fc9075afba3a34e54e784aec 151 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 5.9E-9 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 LK06_RS03325 2a740b14477e9ee07ba2e558e08ffe46 443 SUPERFAMILY SSF46785 14 83 3.4E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03325 2a740b14477e9ee07ba2e558e08ffe46 443 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 74 3.3E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS03325 2a740b14477e9ee07ba2e558e08ffe46 443 SUPERFAMILY SSF53383 70 434 4.84E-55 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS03325 2a740b14477e9ee07ba2e558e08ffe46 443 SMART SM00345 15 74 7.0E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS03325 2a740b14477e9ee07ba2e558e08ffe46 443 Gene3D G3DSA:3.90.1150.10 326 415 3.0E-4 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS03325 2a740b14477e9ee07ba2e558e08ffe46 443 Gene3D G3DSA:3.40.640.10 128 325 3.0E-32 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS03325 2a740b14477e9ee07ba2e558e08ffe46 443 Gene3D G3DSA:1.10.10.10 15 83 1.0E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03325 2a740b14477e9ee07ba2e558e08ffe46 443 Pfam PF00155 Aminotransferase class I and II 157 429 2.7E-17 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS02065 d31ec326c0c4fa5428d6c8ebba1dc8ba 363 SUPERFAMILY SSF50182 168 235 6.87E-15 T 06-07-2017 IPR010920 LSM domain LK06_RS02065 d31ec326c0c4fa5428d6c8ebba1dc8ba 363 SUPERFAMILY SSF82861 84 167 3.01E-12 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 LK06_RS02065 d31ec326c0c4fa5428d6c8ebba1dc8ba 363 SUPERFAMILY SSF82689 242 341 1.2E-20 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 LK06_RS02065 d31ec326c0c4fa5428d6c8ebba1dc8ba 363 Pfam PF00924 Mechanosensitive ion channel 126 330 6.3E-48 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 LK06_RS02065 d31ec326c0c4fa5428d6c8ebba1dc8ba 363 Gene3D G3DSA:2.30.30.60 185 234 1.5E-15 T 06-07-2017 LK06_RS02065 d31ec326c0c4fa5428d6c8ebba1dc8ba 363 Gene3D G3DSA:3.30.70.100 242 328 4.8E-15 T 06-07-2017 LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 Gene3D G3DSA:2.40.50.140 130 186 2.8E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 Gene3D G3DSA:2.30.30.30 3 64 1.6E-30 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 SUPERFAMILY SSF50249 130 186 3.43E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 Gene3D G3DSA:2.40.50.140 65 128 1.0E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 SUPERFAMILY SSF50104 2 64 1.81E-18 T 06-07-2017 IPR008991 Translation protein SH3-like domain LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 2.4E-26 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 9.3E-26 T 06-07-2017 IPR013185 Translation elongation factor, KOW-like LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 SMART SM01185 68 122 1.3E-25 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 PIRSF PIRSF005901 1 187 8.4E-67 T 06-07-2017 IPR020599 Translation elongation factor P/YeiP LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 2.0E-75 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 Hamap MF_00141 Elongation factor P [efp]. 1 186 51.313 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 06-07-2017 IPR013852 Translation elongation factor P/YeiP, conserved site LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 SMART SM00841 130 185 6.9E-33 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 8.4E-21 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 LK06_RS04150 9851ad3c8ee537f24e192606253dac9d 188 SUPERFAMILY SSF50249 66 130 5.14E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS00090 391f61b2b28359aa195527df5e62fa84 497 Gene3D G3DSA:3.40.50.980 3 161 3.3E-35 T 06-07-2017 LK06_RS00090 391f61b2b28359aa195527df5e62fa84 497 Pfam PF00501 AMP-binding enzyme 9 402 1.8E-115 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS00090 391f61b2b28359aa195527df5e62fa84 497 Gene3D G3DSA:3.30.300.30 397 495 6.7E-33 T 06-07-2017 LK06_RS00090 391f61b2b28359aa195527df5e62fa84 497 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS00090 391f61b2b28359aa195527df5e62fa84 497 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 486 4.9E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS00090 391f61b2b28359aa195527df5e62fa84 497 SUPERFAMILY SSF56801 3 495 9.42E-161 T 06-07-2017 LK06_RS00090 391f61b2b28359aa195527df5e62fa84 497 Gene3D G3DSA:2.30.38.10 322 393 2.4E-32 T 06-07-2017 LK06_RS00090 391f61b2b28359aa195527df5e62fa84 497 Gene3D G3DSA:3.40.50.980 162 321 6.3E-51 T 06-07-2017 LK06_RS01695 725fbc1b3212b7aac24417d49c30f992 160 Gene3D G3DSA:3.40.630.30 2 159 8.3E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS01695 725fbc1b3212b7aac24417d49c30f992 160 Pfam PF13508 Acetyltransferase (GNAT) domain 66 138 4.5E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS01695 725fbc1b3212b7aac24417d49c30f992 160 SUPERFAMILY SSF55729 2 150 1.63E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SUPERFAMILY SSF58104 519 647 1.44E-10 T 06-07-2017 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SUPERFAMILY SSF52172 1689 1814 3.84E-37 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Gene3D G3DSA:3.40.50.2300 1684 1814 1.7E-39 T 06-07-2017 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1470 1602 1.2E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SUPERFAMILY SSF55781 1091 1270 3.92E-26 T 06-07-2017 IPR029016 GAF domain-like LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Pfam PF13185 GAF domain 1126 1268 5.6E-17 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SUPERFAMILY SSF58104 611 927 3.92E-21 T 06-07-2017 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Gene3D G3DSA:3.30.450.40 1112 1270 2.0E-20 T 06-07-2017 IPR029016 GAF domain-like LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00448 1695 1809 2.1E-37 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SUPERFAMILY SSF47384 1341 1425 5.1E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SUPERFAMILY SSF55874 1412 1605 2.75E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Gene3D G3DSA:1.10.287.130 1346 1408 3.8E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Gene3D G3DSA:3.30.565.10 1409 1604 1.1E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 683 735 1.3E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 28 80 3.3 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 959 1011 1.5E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 1051 1103 2.1E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 867 919 1.4E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 775 827 3.1E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 591 643 7.6E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 120 183 0.45 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 407 459 3.7E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 499 551 9.8E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 223 275 3.2E-5 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00304 315 367 1.3E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1587 1600 7.4E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1563 1581 7.4E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1546 1556 7.4E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1528 1542 7.4E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Pfam PF00672 HAMP domain 313 363 3.7E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Pfam PF00672 HAMP domain 865 914 1.8E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Pfam PF00672 HAMP domain 588 639 1.2E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00387 1470 1603 5.7E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00388 1355 1423 1.1E-23 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SUPERFAMILY SSF58104 335 468 1.83E-9 T 06-07-2017 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SUPERFAMILY SSF58104 243 374 9.68E-10 T 06-07-2017 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Pfam PF00072 Response regulator receiver domain 1697 1808 6.2E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1356 1423 4.4E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SUPERFAMILY SSF58104 979 1101 5.49E-9 T 06-07-2017 LK06_RS24965 54063ae6b0e93be2124f0db2c6b0bf9e 1816 SMART SM00065 1127 1280 1.4E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS15035 713c76bb73129a817386f88ac7e298db 689 Pfam PF00361 Proton-conducting membrane transporter 167 430 1.9E-46 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15035 713c76bb73129a817386f88ac7e298db 689 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 137 156 2.2E-9 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15035 713c76bb73129a817386f88ac7e298db 689 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 403 429 2.2E-9 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15035 713c76bb73129a817386f88ac7e298db 689 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 252 276 2.2E-9 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 Pfam PF00889 Elongation factor TS 73 277 9.4E-61 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 Gene3D G3DSA:3.30.479.20 57 148 4.2E-20 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 Hamap MF_00050 Elongation factor Ts [tsf]. 1 278 63.018 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 277 1.1E-71 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 Gene3D G3DSA:1.10.286.20 198 241 1.0E-18 T 06-07-2017 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 SUPERFAMILY SSF54713 57 147 1.03E-18 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 SUPERFAMILY SSF46934 3 55 2.38E-15 T 06-07-2017 IPR009060 UBA-like GO:0005515 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 Gene3D G3DSA:1.10.8.10 3 55 9.5E-24 T 06-07-2017 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 Gene3D G3DSA:3.30.479.20 152 193 4.6E-22 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 Gene3D G3DSA:3.30.479.20 242 277 4.6E-22 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS24500 e5a72bf2eb17d58c5c09c9e6b2c7803b 278 SUPERFAMILY SSF54713 150 277 1.57E-37 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS16640 5af9730559d3e64a9cfc8863e2c79fb8 252 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 80 5.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS16640 5af9730559d3e64a9cfc8863e2c79fb8 252 Gene3D G3DSA:1.10.357.10 24 251 2.3E-63 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS16640 5af9730559d3e64a9cfc8863e2c79fb8 252 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 95 248 4.9E-15 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 LK06_RS16640 5af9730559d3e64a9cfc8863e2c79fb8 252 SUPERFAMILY SSF48498 101 251 2.52E-31 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS16640 5af9730559d3e64a9cfc8863e2c79fb8 252 SUPERFAMILY SSF46689 28 90 5.13E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS07885 f7e1acf277d9c0b904b1fde0afc09f98 331 SUPERFAMILY SSF46785 2 83 1.77E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS07885 f7e1acf277d9c0b904b1fde0afc09f98 331 SUPERFAMILY SSF53335 85 320 5.37E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07885 f7e1acf277d9c0b904b1fde0afc09f98 331 Gene3D G3DSA:3.40.50.150 87 320 3.5E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07885 f7e1acf277d9c0b904b1fde0afc09f98 331 Pfam PF00891 O-methyltransferase 99 310 2.1E-38 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 LK06_RS07885 f7e1acf277d9c0b904b1fde0afc09f98 331 PIRSF PIRSF005739 1 323 2.7E-43 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 LK06_RS07885 f7e1acf277d9c0b904b1fde0afc09f98 331 Gene3D G3DSA:1.10.10.10 2 86 5.2E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 SUPERFAMILY SSF47384 248 328 5.89E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 SMART SM00304 200 254 3.8E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 Gene3D G3DSA:3.30.565.10 316 492 9.7E-42 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 SUPERFAMILY SSF55874 319 490 2.23E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 Pfam PF00672 HAMP domain 181 250 8.9E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 Pfam PF00512 His Kinase A (phospho-acceptor) domain 263 328 6.0E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 378 491 7.7E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 429 4.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 489 4.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 443 4.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 470 4.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 SMART SM00388 262 329 1.0E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 Gene3D G3DSA:1.10.287.130 255 315 4.5E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13930 90a73cdbac8739b227231c18e9c10cba 494 SMART SM00387 378 492 1.7E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 Gene3D G3DSA:3.50.50.60 256 338 7.8E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 Gene3D G3DSA:3.50.50.60 4 175 7.8E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 Pfam PF01494 FAD binding domain 4 333 6.1E-61 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 2.3E-37 T 06-07-2017 LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 299 2.3E-37 T 06-07-2017 LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 2.3E-37 T 06-07-2017 LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 319 2.3E-37 T 06-07-2017 LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.3E-37 T 06-07-2017 LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 2.3E-37 T 06-07-2017 LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 SUPERFAMILY SSF51905 3 170 1.58E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29430 74f75506303bdd34e2a94816a8abbd83 496 SUPERFAMILY SSF51905 264 380 1.58E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS23975 1277e367859a2401c0b72e38e1b25bc6 509 Gene3D G3DSA:1.20.1250.20 22 208 3.7E-25 T 06-07-2017 LK06_RS23975 1277e367859a2401c0b72e38e1b25bc6 509 SUPERFAMILY SSF103473 1 213 8.89E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS23975 1277e367859a2401c0b72e38e1b25bc6 509 SUPERFAMILY SSF103473 477 503 8.89E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS23975 1277e367859a2401c0b72e38e1b25bc6 509 SUPERFAMILY SSF103473 260 431 8.89E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS23975 1277e367859a2401c0b72e38e1b25bc6 509 Pfam PF07690 Major Facilitator Superfamily 34 422 2.0E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS23975 1277e367859a2401c0b72e38e1b25bc6 509 Gene3D G3DSA:1.20.1250.20 272 432 6.2E-12 T 06-07-2017 LK06_RS23975 1277e367859a2401c0b72e38e1b25bc6 509 Gene3D G3DSA:1.20.1250.20 478 480 6.2E-12 T 06-07-2017 LK06_RS04660 9535d2a89484f93d674f8901785cfeba 246 Pfam PF00072 Response regulator receiver domain 21 130 4.5E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS04660 9535d2a89484f93d674f8901785cfeba 246 SMART SM00862 167 241 8.9E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS04660 9535d2a89484f93d674f8901785cfeba 246 SMART SM00448 19 130 4.2E-39 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS04660 9535d2a89484f93d674f8901785cfeba 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 168 241 6.2E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS04660 9535d2a89484f93d674f8901785cfeba 246 SUPERFAMILY SSF52172 17 197 1.18E-40 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS04660 9535d2a89484f93d674f8901785cfeba 246 Gene3D G3DSA:1.10.10.10 143 242 1.3E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04660 9535d2a89484f93d674f8901785cfeba 246 Gene3D G3DSA:3.40.50.2300 12 139 2.4E-39 T 06-07-2017 LK06_RS25070 ce44bd7bb415704fc8af2feceb1f3e30 278 SUPERFAMILY SSF53850 6 261 3.44E-54 T 06-07-2017 LK06_RS25070 ce44bd7bb415704fc8af2feceb1f3e30 278 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 61 74 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 LK06_RS25070 ce44bd7bb415704fc8af2feceb1f3e30 278 Gene3D G3DSA:3.40.190.10 119 224 5.3E-21 T 06-07-2017 LK06_RS25070 ce44bd7bb415704fc8af2feceb1f3e30 278 SMART SM00062 39 263 4.6E-68 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LK06_RS25070 ce44bd7bb415704fc8af2feceb1f3e30 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 261 1.2E-47 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LK06_RS25070 ce44bd7bb415704fc8af2feceb1f3e30 278 Gene3D G3DSA:3.40.190.10 225 261 1.7E-29 T 06-07-2017 LK06_RS25070 ce44bd7bb415704fc8af2feceb1f3e30 278 Gene3D G3DSA:3.40.190.10 38 118 1.7E-29 T 06-07-2017 LK06_RS00905 6bf8d27573d820b7cb5711ce868c4da1 128 Gene3D G3DSA:2.30.110.10 6 127 1.0E-10 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS00905 6bf8d27573d820b7cb5711ce868c4da1 128 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 4 127 2.7E-46 T 06-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative LK06_RS00905 6bf8d27573d820b7cb5711ce868c4da1 128 SUPERFAMILY SSF50475 3 126 1.4E-14 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS00905 6bf8d27573d820b7cb5711ce868c4da1 128 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 66 3.3E-4 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS09305 a616386a7419ffa693688392406dcfb0 300 Gene3D G3DSA:1.10.3470.10 41 259 1.9E-9 T 06-07-2017 IPR029022 ABC transporter, BtuC-like LK06_RS09305 a616386a7419ffa693688392406dcfb0 300 SUPERFAMILY SSF81345 3 259 2.75E-35 T 06-07-2017 IPR029022 ABC transporter, BtuC-like LK06_RS09305 a616386a7419ffa693688392406dcfb0 300 Pfam PF00950 ABC 3 transport family 6 259 2.9E-65 T 06-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 LK06_RS15535 0f41ba42ac54300d668f9d7346000b4c 633 Gene3D G3DSA:3.40.50.720 1 136 6.7E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15535 0f41ba42ac54300d668f9d7346000b4c 633 Pfam PF02254 TrkA-N domain 382 490 6.3E-22 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LK06_RS15535 0f41ba42ac54300d668f9d7346000b4c 633 Pfam PF02254 TrkA-N domain 65 136 6.6E-7 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LK06_RS15535 0f41ba42ac54300d668f9d7346000b4c 633 SUPERFAMILY SSF51735 378 490 1.67E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15535 0f41ba42ac54300d668f9d7346000b4c 633 SUPERFAMILY SSF51735 69 135 2.36E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15535 0f41ba42ac54300d668f9d7346000b4c 633 Gene3D G3DSA:3.40.50.720 379 531 8.8E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31615 070b466f80e017e441a03c9b47f43c7f 519 SUPERFAMILY SSF53067 246 479 2.0E-47 T 06-07-2017 LK06_RS31615 070b466f80e017e441a03c9b47f43c7f 519 Gene3D G3DSA:3.30.420.40 3 244 3.1E-46 T 06-07-2017 LK06_RS31615 070b466f80e017e441a03c9b47f43c7f 519 Gene3D G3DSA:3.30.420.40 247 479 2.3E-43 T 06-07-2017 LK06_RS31615 070b466f80e017e441a03c9b47f43c7f 519 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 255 436 3.1E-25 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 LK06_RS31615 070b466f80e017e441a03c9b47f43c7f 519 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 244 1.6E-51 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 LK06_RS31615 070b466f80e017e441a03c9b47f43c7f 519 PIRSF PIRSF000538 1 483 2.0E-96 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LK06_RS31615 070b466f80e017e441a03c9b47f43c7f 519 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 353 373 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LK06_RS31615 070b466f80e017e441a03c9b47f43c7f 519 SUPERFAMILY SSF53067 3 247 3.13E-54 T 06-07-2017 LK06_RS28220 05713aaed31784a39ec96d05ad118c15 289 SUPERFAMILY SSF53850 85 264 4.83E-29 T 06-07-2017 LK06_RS28220 05713aaed31784a39ec96d05ad118c15 289 Gene3D G3DSA:1.10.10.10 3 80 6.6E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28220 05713aaed31784a39ec96d05ad118c15 289 Pfam PF03466 LysR substrate binding domain 87 276 1.9E-30 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS28220 05713aaed31784a39ec96d05ad118c15 289 SUPERFAMILY SSF46785 2 109 1.69E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28220 05713aaed31784a39ec96d05ad118c15 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS28220 05713aaed31784a39ec96d05ad118c15 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS28220 05713aaed31784a39ec96d05ad118c15 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS28220 05713aaed31784a39ec96d05ad118c15 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.0E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS28220 05713aaed31784a39ec96d05ad118c15 289 Gene3D G3DSA:3.40.190.10 88 168 1.6E-15 T 06-07-2017 LK06_RS28220 05713aaed31784a39ec96d05ad118c15 289 Gene3D G3DSA:3.40.190.10 169 241 8.2E-9 T 06-07-2017 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 555 7.9E-94 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 PRINTS PR01042 Aspartyl-tRNA synthetase signature 516 530 1.2E-21 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 PRINTS PR01042 Aspartyl-tRNA synthetase signature 472 488 1.2E-21 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 1.2E-21 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 1.2E-21 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 Pfam PF01336 OB-fold nucleic acid binding domain 21 104 3.1E-14 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 Gene3D G3DSA:3.30.930.10 136 282 8.7E-97 T 06-07-2017 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 Gene3D G3DSA:3.30.930.10 410 582 8.7E-97 T 06-07-2017 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 Gene3D G3DSA:2.40.50.140 4 108 7.1E-34 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS15300 bebea1476b082609937b73002738d2c4 587 Gene3D G3DSA:3.30.1360.30 283 409 4.9E-42 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 580 6.4E-185 T 06-07-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 Pfam PF02938 GAD domain 315 403 6.6E-20 T 06-07-2017 IPR029351 GAD domain Reactome: R-HSA-379726 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 SUPERFAMILY SSF55681 117 298 6.89E-93 T 06-07-2017 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 SUPERFAMILY SSF55681 422 582 6.89E-93 T 06-07-2017 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 SUPERFAMILY SSF55261 297 414 1.08E-34 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 LK06_RS15300 bebea1476b082609937b73002738d2c4 587 SUPERFAMILY SSF50249 4 107 4.57E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS15300 bebea1476b082609937b73002738d2c4 587 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 4 561 33.014 T 06-07-2017 LK06_RS05235 c1f2db0ce91e04ea25576bd62b17e057 172 Gene3D G3DSA:3.40.50.300 4 165 1.4E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05235 c1f2db0ce91e04ea25576bd62b17e057 172 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 8 159 4.2E-54 T 06-07-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 LK06_RS05235 c1f2db0ce91e04ea25576bd62b17e057 172 Pfam PF01202 Shikimate kinase 14 162 1.1E-8 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 LK06_RS05235 c1f2db0ce91e04ea25576bd62b17e057 172 SUPERFAMILY SSF52540 3 167 1.15E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12685 2b605fc3772b9ab39ede2568b6a9b073 399 Pfam PF07730 Histidine kinase 208 273 8.0E-13 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS12685 2b605fc3772b9ab39ede2568b6a9b073 399 SUPERFAMILY SSF55874 287 394 2.6E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS12685 2b605fc3772b9ab39ede2568b6a9b073 399 Pfam PF13796 Putative sensor 40 155 3.9E-25 T 06-07-2017 IPR025828 Putative sensor domain LK06_RS23715 a2deae653adc2fe94b66496227bee30b 394 Pfam PF10282 Lactonase, 7-bladed beta-propeller 284 362 1.1E-4 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 LK06_RS23715 a2deae653adc2fe94b66496227bee30b 394 SMART SM00564 78 111 25.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS23715 a2deae653adc2fe94b66496227bee30b 394 SMART SM00564 336 368 14.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS23715 a2deae653adc2fe94b66496227bee30b 394 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 85 120 5.7E-13 T 06-07-2017 IPR011964 YVTN beta-propeller repeat LK06_RS23715 a2deae653adc2fe94b66496227bee30b 394 Gene3D G3DSA:2.130.10.10 83 381 2.8E-59 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS23715 a2deae653adc2fe94b66496227bee30b 394 SUPERFAMILY SSF51004 81 375 3.14E-63 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain LK06_RS11490 fd8070a325ac7dea1fbe7a24649c34ae 400 SMART SM00091 67 133 3.0E-11 T 06-07-2017 IPR000014 PAS domain LK06_RS11490 fd8070a325ac7dea1fbe7a24649c34ae 400 Gene3D G3DSA:3.30.565.10 258 394 1.8E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11490 fd8070a325ac7dea1fbe7a24649c34ae 400 SUPERFAMILY SSF55874 301 392 3.01E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11490 fd8070a325ac7dea1fbe7a24649c34ae 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 393 1.6E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11490 fd8070a325ac7dea1fbe7a24649c34ae 400 SUPERFAMILY SSF55785 60 179 1.3E-24 T 06-07-2017 IPR000014 PAS domain LK06_RS11490 fd8070a325ac7dea1fbe7a24649c34ae 400 Gene3D G3DSA:3.30.450.20 63 179 8.1E-26 T 06-07-2017 LK06_RS11490 fd8070a325ac7dea1fbe7a24649c34ae 400 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 64 188 1.5E-24 T 06-07-2017 IPR000014 PAS domain LK06_RS11490 fd8070a325ac7dea1fbe7a24649c34ae 400 SMART SM00387 304 394 3.1E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11490 fd8070a325ac7dea1fbe7a24649c34ae 400 Pfam PF00989 PAS fold 68 178 8.3E-18 T 06-07-2017 IPR013767 PAS fold GO:0006355 LK06_RS11490 fd8070a325ac7dea1fbe7a24649c34ae 400 Pfam PF07730 Histidine kinase 200 263 1.2E-10 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS06775 edb5841e04fda31574637a95461d4f79 286 Gene3D G3DSA:1.10.260.40 12 72 5.6E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS06775 edb5841e04fda31574637a95461d4f79 286 Pfam PF13560 Helix-turn-helix domain 15 74 1.3E-10 T 06-07-2017 LK06_RS06775 edb5841e04fda31574637a95461d4f79 286 SMART SM00530 18 73 5.1E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS06775 edb5841e04fda31574637a95461d4f79 286 SUPERFAMILY SSF47413 14 72 4.15E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS02790 0d5f8cc567cb53c6d62f30751a3df239 128 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 43 94 6.6E-10 T 06-07-2017 IPR027805 Transposase, Helix-turn-helix domain LK06_RS09865 6130d1379a1dbcf552e04891623fadb5 225 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 157 6.3E-19 T 06-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 LK06_RS09865 6130d1379a1dbcf552e04891623fadb5 225 Pfam PF04093 rod shape-determining protein MreD 3 135 2.5E-5 T 06-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 LK06_RS17745 5e357b55180f911b4bb5d3d6754f59e0 230 SUPERFAMILY SSF48498 82 228 3.56E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS17745 5e357b55180f911b4bb5d3d6754f59e0 230 SUPERFAMILY SSF46689 11 75 4.69E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS17745 5e357b55180f911b4bb5d3d6754f59e0 230 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 77 224 5.1E-22 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 LK06_RS17745 5e357b55180f911b4bb5d3d6754f59e0 230 Gene3D G3DSA:1.10.10.60 4 70 2.2E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS17745 5e357b55180f911b4bb5d3d6754f59e0 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 1.5E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17745 5e357b55180f911b4bb5d3d6754f59e0 230 Gene3D G3DSA:1.10.357.10 71 225 2.6E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS22495 c5d0e1119fdbddaf46947f2feaa6fcd3 299 PIRSF PIRSF006278 3 296 4.9E-78 T 06-07-2017 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase LK06_RS22495 c5d0e1119fdbddaf46947f2feaa6fcd3 299 SUPERFAMILY SSF53686 12 293 4.03E-47 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS22495 c5d0e1119fdbddaf46947f2feaa6fcd3 299 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 12 293 2.4E-20 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS22495 c5d0e1119fdbddaf46947f2feaa6fcd3 299 Gene3D G3DSA:3.40.50.1100 100 293 9.9E-39 T 06-07-2017 LK06_RS02375 ca9eb1ef9a6137730a9e465d987e8f94 429 Pfam PF00202 Aminotransferase class-III 33 421 6.7E-115 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS02375 ca9eb1ef9a6137730a9e465d987e8f94 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 247 284 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS02375 ca9eb1ef9a6137730a9e465d987e8f94 429 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 20 425 1.1E-164 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 LK06_RS02375 ca9eb1ef9a6137730a9e465d987e8f94 429 Gene3D G3DSA:3.40.640.10 70 332 5.9E-85 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS02375 ca9eb1ef9a6137730a9e465d987e8f94 429 SUPERFAMILY SSF53383 12 427 1.84E-116 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS02375 ca9eb1ef9a6137730a9e465d987e8f94 429 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 8 429 48.928 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 LK06_RS02375 ca9eb1ef9a6137730a9e465d987e8f94 429 Gene3D G3DSA:3.90.1150.10 337 427 1.9E-50 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS02375 ca9eb1ef9a6137730a9e465d987e8f94 429 Gene3D G3DSA:3.90.1150.10 11 69 1.9E-50 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 SUPERFAMILY SSF50494 185 370 1.36E-32 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 Gene3D G3DSA:2.40.10.10 266 364 6.1E-28 T 06-07-2017 LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 Gene3D G3DSA:3.30.300.50 104 143 7.7E-5 T 06-07-2017 LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 Gene3D G3DSA:3.30.300.50 46 102 3.3E-5 T 06-07-2017 LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 342 356 9.3E-23 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 317 340 9.3E-23 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 208 222 9.3E-23 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 Pfam PF02983 Alpha-lytic protease prodomain 104 156 2.9E-13 T 06-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 Gene3D G3DSA:2.40.10.10 178 265 1.6E-24 T 06-07-2017 LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 Pfam PF00089 Trypsin 209 369 2.3E-11 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 326 337 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site LK06_RS01035 0e3562d32cab97769c86cdde73e8e7fb 444 PIRSF PIRSF001134 1 380 1.1E-115 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS06335 cbe6ff11ab5e26fde8fdd3bccbc5f1e4 134 Pfam PF06339 Ectoine synthase 2 127 2.7E-55 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS06335 cbe6ff11ab5e26fde8fdd3bccbc5f1e4 134 SUPERFAMILY SSF51182 4 134 6.21E-20 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS06335 cbe6ff11ab5e26fde8fdd3bccbc5f1e4 134 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 119 2.0E-59 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS06335 cbe6ff11ab5e26fde8fdd3bccbc5f1e4 134 Hamap MF_01255 L-ectoine synthase [ectC]. 1 129 38.073 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LK06_RS06335 cbe6ff11ab5e26fde8fdd3bccbc5f1e4 134 Gene3D G3DSA:2.60.120.10 25 112 4.3E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS16245 fc0c560712d0acd70c1bf8f2c2525b2b 427 SUPERFAMILY SSF54909 72 420 4.83E-82 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS16245 fc0c560712d0acd70c1bf8f2c2525b2b 427 Pfam PF04261 Dyp-type peroxidase family 77 414 4.8E-107 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LK06_RS16245 fc0c560712d0acd70c1bf8f2c2525b2b 427 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 77 415 7.1E-93 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LK06_RS16245 fc0c560712d0acd70c1bf8f2c2525b2b 427 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 25 426 2.2E-156 T 06-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 LK06_RS31675 d6671a9edbe17a747cf9190489cc5b2a 165 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 34 124 4.4E-23 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 LK06_RS31675 d6671a9edbe17a747cf9190489cc5b2a 165 Pfam PF04075 Domain of unknown function (DUF385) 33 128 8.2E-15 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 LK06_RS31675 d6671a9edbe17a747cf9190489cc5b2a 165 SUPERFAMILY SSF50475 38 128 3.68E-7 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS09115 ea244f1a51891b1d0a9b4dec7d112b73 263 SMART SM00530 30 91 0.005 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS09115 ea244f1a51891b1d0a9b4dec7d112b73 263 Gene3D G3DSA:1.10.260.40 30 104 3.8E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS09115 ea244f1a51891b1d0a9b4dec7d112b73 263 Pfam PF13560 Helix-turn-helix domain 28 90 8.7E-8 T 06-07-2017 LK06_RS09115 ea244f1a51891b1d0a9b4dec7d112b73 263 SUPERFAMILY SSF47413 22 95 1.04E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 662 30.59 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 SUPERFAMILY SSF47781 554 664 1.37E-25 T 06-07-2017 IPR010994 RuvA domain 2-like LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 Pfam PF02151 UvrB/uvrC motif 211 242 2.9E-8 T 06-07-2017 IPR001943 UVR domain GO:0005515 LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 Gene3D G3DSA:3.40.1440.10 18 95 4.4E-10 T 06-07-2017 IPR027299 GIY-YIG domain LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 SMART SM00465 17 99 4.0E-20 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 475 9.1E-127 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 SMART SM00278 643 662 0.043 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 SMART SM00278 611 630 17.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 SUPERFAMILY SSF82771 17 101 5.62E-23 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 393 597 4.8E-52 T 06-07-2017 IPR001162 UvrC family homology region LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 Pfam PF14520 Helix-hairpin-helix domain 613 663 1.2E-10 T 06-07-2017 LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 Gene3D G3DSA:1.10.150.20 613 660 5.4E-21 T 06-07-2017 LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 Gene3D G3DSA:4.10.860.10 187 246 2.3E-18 T 06-07-2017 IPR001943 UVR domain GO:0005515 LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 SUPERFAMILY SSF46600 194 246 7.59E-13 T 06-07-2017 IPR001943 UVR domain GO:0005515 LK06_RS06645 ba91eee85888a0f1484b58989fc23eb3 710 Pfam PF01541 GIY-YIG catalytic domain 19 92 2.8E-11 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily LK06_RS28805 21332dece2b21c4098e982684a5d52f3 387 Gene3D G3DSA:3.60.15.10 64 355 1.3E-102 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS28805 21332dece2b21c4098e982684a5d52f3 387 SUPERFAMILY SSF56281 191 340 8.78E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS28805 21332dece2b21c4098e982684a5d52f3 387 SUPERFAMILY SSF56281 87 164 8.78E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS28805 21332dece2b21c4098e982684a5d52f3 387 Pfam PF12706 Beta-lactamase superfamily domain 104 304 7.3E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS06075 7a60f243cbfdaf224da0601f1d5c6234 457 SUPERFAMILY SSF89796 25 199 1.7E-20 T 06-07-2017 IPR023606 CoA-transferase family III domain LK06_RS06075 7a60f243cbfdaf224da0601f1d5c6234 457 SUPERFAMILY SSF89796 207 400 9.42E-50 T 06-07-2017 IPR023606 CoA-transferase family III domain LK06_RS06075 7a60f243cbfdaf224da0601f1d5c6234 457 Pfam PF02515 CoA-transferase family III 209 398 7.9E-44 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 LK06_RS06075 7a60f243cbfdaf224da0601f1d5c6234 457 Pfam PF02515 CoA-transferase family III 30 185 1.4E-5 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 LK06_RS06075 7a60f243cbfdaf224da0601f1d5c6234 457 Gene3D G3DSA:3.40.50.10540 207 398 2.1E-60 T 06-07-2017 IPR023606 CoA-transferase family III domain LK06_RS06075 7a60f243cbfdaf224da0601f1d5c6234 457 Gene3D G3DSA:3.40.50.10540 27 127 1.5E-5 T 06-07-2017 IPR023606 CoA-transferase family III domain LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 SUPERFAMILY SSF50249 32 133 8.95E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 SUPERFAMILY SSF50249 113 191 1.34E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 Gene3D G3DSA:2.40.50.140 116 192 7.8E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 Gene3D G3DSA:2.40.50.140 30 109 9.2E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 SUPERFAMILY SSF50249 280 368 4.0E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 SUPERFAMILY SSF50249 210 292 3.22E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 SMART SM00316 37 108 1.9E-16 T 06-07-2017 IPR022967 RNA-binding domain, S1 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 SMART SM00316 210 280 1.3E-27 T 06-07-2017 IPR022967 RNA-binding domain, S1 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 SMART SM00316 124 191 6.5E-11 T 06-07-2017 IPR022967 RNA-binding domain, S1 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 SMART SM00316 295 366 1.1E-26 T 06-07-2017 IPR022967 RNA-binding domain, S1 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 Pfam PF00575 S1 RNA binding domain 124 191 1.0E-13 T 06-07-2017 IPR003029 S1 domain GO:0003676 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 Pfam PF00575 S1 RNA binding domain 209 280 9.4E-26 T 06-07-2017 IPR003029 S1 domain GO:0003676 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 Pfam PF00575 S1 RNA binding domain 294 366 3.5E-23 T 06-07-2017 IPR003029 S1 domain GO:0003676 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 Pfam PF00575 S1 RNA binding domain 36 108 4.9E-15 T 06-07-2017 IPR003029 S1 domain GO:0003676 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 PRINTS PR00681 Ribosomal protein S1 signature 105 124 3.8E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 PRINTS PR00681 Ribosomal protein S1 signature 310 329 3.8E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 PRINTS PR00681 Ribosomal protein S1 signature 39 57 3.8E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 PRINTS PR00681 Ribosomal protein S1 signature 349 367 3.8E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 PRINTS PR00681 Ribosomal protein S1 signature 175 195 3.8E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 PRINTS PR00681 Ribosomal protein S1 signature 232 253 3.8E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 PRINTS PR00681 Ribosomal protein S1 signature 129 145 3.8E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 PRINTS PR00681 Ribosomal protein S1 signature 57 71 3.8E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 PRINTS PR00681 Ribosomal protein S1 signature 146 163 3.8E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 Gene3D G3DSA:2.40.50.140 287 369 1.9E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS06850 3531753e8cdf69675ca6b0ec3618d45a 496 Gene3D G3DSA:2.40.50.140 205 286 1.8E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS20855 8ad12cce542396e6f2ec2c5c99b7acfb 69 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 3 62 1.1E-16 T 06-07-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 Gene3D G3DSA:3.30.450.40 339 481 4.1E-19 T 06-07-2017 IPR029016 GAF domain-like LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 Pfam PF13185 GAF domain 340 475 9.0E-11 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 Pfam PF00989 PAS fold 201 300 7.2E-7 T 06-07-2017 IPR013767 PAS fold GO:0006355 LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 SUPERFAMILY SSF55781 341 479 1.59E-19 T 06-07-2017 IPR029016 GAF domain-like LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 Gene3D G3DSA:3.30.450.40 494 673 2.0E-20 T 06-07-2017 IPR029016 GAF domain-like LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 SMART SM00065 340 484 3.7E-11 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 SMART SM00065 505 675 0.039 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 SUPERFAMILY SSF55781 490 673 2.62E-11 T 06-07-2017 IPR029016 GAF domain-like LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 Gene3D G3DSA:3.30.450.20 201 300 4.4E-12 T 06-07-2017 LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 SUPERFAMILY SSF81606 705 913 1.52E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 SMART SM00331 696 913 5.9E-70 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 Pfam PF13581 Histidine kinase-like ATPase domain 58 169 6.5E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 SUPERFAMILY SSF55785 201 295 5.41E-15 T 06-07-2017 IPR000014 PAS domain LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 202 300 1.2E-8 T 06-07-2017 IPR000014 PAS domain LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 723 913 3.4E-44 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS24955 6b366ac92f9c7f890b4ee6a8e3eff764 920 Pfam PF13492 GAF domain 618 667 1.5E-6 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS09705 e357da045cccb016314f760135c139ad 239 Gene3D G3DSA:1.10.260.40 4 52 4.4E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS09705 e357da045cccb016314f760135c139ad 239 Gene3D G3DSA:3.30.870.10 68 179 3.0E-4 T 06-07-2017 LK06_RS09705 e357da045cccb016314f760135c139ad 239 SUPERFAMILY SSF56024 78 156 4.32E-7 T 06-07-2017 LK06_RS05000 4b1a2c680486379fb5f47baf9efd14e6 419 SUPERFAMILY SSF103473 12 386 3.53E-30 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS05000 4b1a2c680486379fb5f47baf9efd14e6 419 Pfam PF07690 Major Facilitator Superfamily 21 327 2.9E-18 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS05000 4b1a2c680486379fb5f47baf9efd14e6 419 Gene3D G3DSA:1.20.1250.20 208 386 1.4E-7 T 06-07-2017 LK06_RS05000 4b1a2c680486379fb5f47baf9efd14e6 419 Gene3D G3DSA:1.20.1250.20 28 199 7.8E-13 T 06-07-2017 LK06_RS01190 4a8bd765b1f88aa5935c360a11dad5c3 154 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 26 96 1.8E-5 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS01190 4a8bd765b1f88aa5935c360a11dad5c3 154 SUPERFAMILY SSF50475 13 134 1.11E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS01190 4a8bd765b1f88aa5935c360a11dad5c3 154 Gene3D G3DSA:2.30.110.10 10 149 1.1E-39 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS17030 c610a7df46ee67b2fd98952ebf7fe720 265 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 21 236 7.7E-22 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type LK06_RS17030 c610a7df46ee67b2fd98952ebf7fe720 265 SUPERFAMILY SSF109854 10 163 1.22E-15 T 06-07-2017 LK06_RS17030 c610a7df46ee67b2fd98952ebf7fe720 265 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 22 159 5.4E-17 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 LK06_RS17030 c610a7df46ee67b2fd98952ebf7fe720 265 Gene3D G3DSA:1.20.120.450 21 95 2.2E-7 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase LK06_RS18630 4a912c0b2cccff2ef0ecc2580ad4090d 108 Gene3D G3DSA:1.10.1900.10 14 100 6.6E-30 T 06-07-2017 IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein GO:0003723 LK06_RS18630 4a912c0b2cccff2ef0ecc2580ad4090d 108 SUPERFAMILY SSF158560 3 98 7.46E-28 T 06-07-2017 LK06_RS18630 4a912c0b2cccff2ef0ecc2580ad4090d 108 Pfam PF06304 Protein of unknown function (DUF1048) 5 100 6.3E-34 T 06-07-2017 IPR008316 Uncharacterised conserved protein UCP029876 LK06_RS04485 b2fe5595ef4955b83aca25ac19d4418a 185 Gene3D G3DSA:1.10.3300.10 3 182 2.2E-52 T 06-07-2017 IPR023286 ABATE domain LK06_RS04485 b2fe5595ef4955b83aca25ac19d4418a 185 Pfam PF11706 CGNR zinc finger 137 180 4.4E-18 T 06-07-2017 IPR021005 Zinc finger, CGNR LK06_RS04485 b2fe5595ef4955b83aca25ac19d4418a 185 SUPERFAMILY SSF160904 2 179 6.41E-48 T 06-07-2017 LK06_RS04485 b2fe5595ef4955b83aca25ac19d4418a 185 Pfam PF07336 Putative stress-induced transcription regulator 13 121 4.3E-14 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator LK06_RS02295 7a17b2e3379a9ba543ba08a334052fff 225 SUPERFAMILY SSF52540 21 223 1.77E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02295 7a17b2e3379a9ba543ba08a334052fff 225 Hamap MF_01389 Urease accessory protein UreG [ureG]. 25 223 43.311 T 06-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 LK06_RS02295 7a17b2e3379a9ba543ba08a334052fff 225 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 27 218 1.4E-82 T 06-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 LK06_RS02295 7a17b2e3379a9ba543ba08a334052fff 225 PIRSF PIRSF005624 11 225 4.2E-46 T 06-07-2017 LK06_RS02295 7a17b2e3379a9ba543ba08a334052fff 225 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 29 199 1.3E-33 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain LK06_RS02295 7a17b2e3379a9ba543ba08a334052fff 225 Gene3D G3DSA:3.40.50.300 25 214 1.1E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 Gene3D G3DSA:3.40.50.20 16 149 5.3E-37 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 127 138 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 SUPERFAMILY SSF56059 160 379 4.09E-54 T 06-07-2017 LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 PIRSF PIRSF039102 15 383 4.8E-110 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 Gene3D G3DSA:3.30.1490.20 189 248 8.4E-21 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 18 377 1.9E-103 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 SUPERFAMILY SSF52440 16 158 8.06E-35 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 Pfam PF07478 D-ala D-ala ligase C-terminus 168 375 5.1E-65 T 06-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 Pfam PF01820 D-ala D-ala ligase N-terminus 18 150 3.0E-34 T 06-07-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 Gene3D G3DSA:3.30.470.20 250 380 2.6E-46 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 17 378 41.496 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS24220 2e6e4b12d3cef51de118a55ee0fd834d 385 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 320 348 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS12035 214c8054d41786bae7bfc38751b4e7cf 225 Pfam PF00072 Response regulator receiver domain 4 114 7.0E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS12035 214c8054d41786bae7bfc38751b4e7cf 225 Gene3D G3DSA:1.10.10.10 129 224 2.8E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12035 214c8054d41786bae7bfc38751b4e7cf 225 Gene3D G3DSA:3.40.50.2300 2 123 7.6E-40 T 06-07-2017 LK06_RS12035 214c8054d41786bae7bfc38751b4e7cf 225 SMART SM00448 2 113 1.9E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS12035 214c8054d41786bae7bfc38751b4e7cf 225 SUPERFAMILY SSF52172 1 184 3.08E-42 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS12035 214c8054d41786bae7bfc38751b4e7cf 225 SMART SM00862 146 222 4.4E-29 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS12035 214c8054d41786bae7bfc38751b4e7cf 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 3.6E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 SMART SM00091 1 67 0.039 T 06-07-2017 IPR000014 PAS domain LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 SMART SM00091 114 180 45.0 T 06-07-2017 IPR000014 PAS domain LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 SUPERFAMILY SSF55785 126 237 3.8E-9 T 06-07-2017 IPR000014 PAS domain LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 SUPERFAMILY SSF55781 255 424 2.84E-13 T 06-07-2017 IPR029016 GAF domain-like LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 SMART SM00331 440 661 3.2E-36 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 Gene3D G3DSA:3.30.450.40 240 420 6.7E-33 T 06-07-2017 IPR029016 GAF domain-like LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 Pfam PF08448 PAS fold 122 231 6.1E-17 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 Pfam PF01590 GAF domain 328 412 8.0E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 SUPERFAMILY SSF81606 457 660 2.09E-8 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 469 661 9.4E-52 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 Pfam PF00989 PAS fold 10 52 3.7E-5 T 06-07-2017 IPR013767 PAS fold GO:0006355 LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 Gene3D G3DSA:3.30.450.20 122 228 1.2E-12 T 06-07-2017 LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 Gene3D G3DSA:3.30.450.20 7 100 9.5E-10 T 06-07-2017 LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 122 236 9.2E-8 T 06-07-2017 IPR000014 PAS domain LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 SUPERFAMILY SSF55785 7 94 1.83E-11 T 06-07-2017 IPR000014 PAS domain LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 Pfam PF13581 Histidine kinase-like ATPase domain 674 782 3.8E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 Gene3D G3DSA:3.30.565.10 704 791 4.1E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01110 82155a8b8ff1accd934674ea82f1b09d 802 SUPERFAMILY SSF55874 701 789 3.01E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00495 bf773e68f72e106781fa5edf9366396f 552 SUPERFAMILY SSF56601 250 549 2.65E-43 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS00495 bf773e68f72e106781fa5edf9366396f 552 Pfam PF00905 Penicillin binding protein transpeptidase domain 278 549 2.4E-26 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS00495 bf773e68f72e106781fa5edf9366396f 552 Gene3D G3DSA:3.40.710.10 253 549 1.2E-41 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS00495 bf773e68f72e106781fa5edf9366396f 552 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 66 173 1.1E-7 T 06-07-2017 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 LK06_RS27335 842414e02f720ca8387484c7457bf607 276 Gene3D G3DSA:3.30.450.40 14 126 4.5E-9 T 06-07-2017 IPR029016 GAF domain-like LK06_RS27335 842414e02f720ca8387484c7457bf607 276 Pfam PF00196 Bacterial regulatory proteins, luxR family 214 268 7.2E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27335 842414e02f720ca8387484c7457bf607 276 SUPERFAMILY SSF55781 14 145 3.19E-9 T 06-07-2017 IPR029016 GAF domain-like LK06_RS27335 842414e02f720ca8387484c7457bf607 276 Gene3D G3DSA:1.10.10.10 215 275 2.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27335 842414e02f720ca8387484c7457bf607 276 SMART SM00421 212 269 1.4E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27335 842414e02f720ca8387484c7457bf607 276 Pfam PF01590 GAF domain 48 145 1.3E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS27335 842414e02f720ca8387484c7457bf607 276 ProSitePatterns PS00622 LuxR-type HTH domain signature. 229 256 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27335 842414e02f720ca8387484c7457bf607 276 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 229 245 7.3E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27335 842414e02f720ca8387484c7457bf607 276 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 215 229 7.3E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27335 842414e02f720ca8387484c7457bf607 276 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 245 257 7.3E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27335 842414e02f720ca8387484c7457bf607 276 SUPERFAMILY SSF46894 202 275 1.09E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS31695 f602f1a42cd6d5207db60e0b103636e2 241 SUPERFAMILY SSF56214 119 232 3.84E-14 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS31695 f602f1a42cd6d5207db60e0b103636e2 241 SUPERFAMILY SSF56214 19 105 4.36E-10 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS31695 f602f1a42cd6d5207db60e0b103636e2 241 Gene3D G3DSA:3.90.470.20 129 190 1.2E-11 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS31695 f602f1a42cd6d5207db60e0b103636e2 241 Gene3D G3DSA:3.90.470.20 17 128 2.7E-12 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS31695 f602f1a42cd6d5207db60e0b103636e2 241 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 120 188 1.5E-7 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS14525 011f0613ba1b6ce2027e0f507703005f 231 SUPERFAMILY SSF46785 7 78 2.04E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14525 011f0613ba1b6ce2027e0f507703005f 231 Gene3D G3DSA:1.20.120.530 115 225 1.0E-13 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS14525 011f0613ba1b6ce2027e0f507703005f 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 6.6E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS14525 011f0613ba1b6ce2027e0f507703005f 231 SMART SM00345 16 74 1.7E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS14525 011f0613ba1b6ce2027e0f507703005f 231 Gene3D G3DSA:1.10.10.10 5 74 3.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14525 011f0613ba1b6ce2027e0f507703005f 231 SUPERFAMILY SSF48008 115 226 8.63E-14 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS14525 011f0613ba1b6ce2027e0f507703005f 231 Pfam PF07729 FCD domain 116 214 1.2E-9 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS27695 ded244b747191f16a677e1d9522e102b 289 SUPERFAMILY SSF47413 29 79 2.52E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS27695 ded244b747191f16a677e1d9522e102b 289 Gene3D G3DSA:1.10.260.40 4 79 3.2E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS27695 ded244b747191f16a677e1d9522e102b 289 Pfam PF13560 Helix-turn-helix domain 5 84 3.9E-17 T 06-07-2017 LK06_RS27695 ded244b747191f16a677e1d9522e102b 289 SMART SM00530 9 81 1.2E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS01895 9cc14165849434940a6554b6d615dc34 519 SUPERFAMILY SSF51905 11 319 7.59E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01895 9cc14165849434940a6554b6d615dc34 519 SUPERFAMILY SSF51905 452 490 7.59E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01895 9cc14165849434940a6554b6d615dc34 519 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 12 495 1.6E-168 T 06-07-2017 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 LK06_RS01895 9cc14165849434940a6554b6d615dc34 519 Gene3D G3DSA:3.50.50.60 144 154 4.0E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01895 9cc14165849434940a6554b6d615dc34 519 Gene3D G3DSA:3.50.50.60 12 101 4.0E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01895 9cc14165849434940a6554b6d615dc34 519 Gene3D G3DSA:3.50.50.60 220 354 4.0E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01895 9cc14165849434940a6554b6d615dc34 519 Pfam PF01593 Flavin containing amine oxidoreductase 19 490 7.0E-50 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 LK06_RS01895 9cc14165849434940a6554b6d615dc34 519 ProSitePatterns PS00982 Bacterial-type phytoene dehydrogenase signature. 462 482 - T 06-07-2017 IPR008150 Phytoene dehydrogenase, bacterial-type, conserved site LK06_RS12125 948e6253c539c03bf49023bca97622f6 280 SUPERFAMILY SSF46689 18 81 5.55E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS12125 948e6253c539c03bf49023bca97622f6 280 Gene3D G3DSA:3.40.50.10490 70 238 5.9E-7 T 06-07-2017 LK06_RS12125 948e6253c539c03bf49023bca97622f6 280 Pfam PF01418 Helix-turn-helix domain, rpiR family 17 78 4.8E-11 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 LK06_RS12125 948e6253c539c03bf49023bca97622f6 280 SUPERFAMILY SSF53697 93 240 6.92E-10 T 06-07-2017 LK06_RS12125 948e6253c539c03bf49023bca97622f6 280 Gene3D G3DSA:1.10.10.10 18 69 1.3E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18195 92cad5cfc2a99d7939f71bf3b987906e 582 SUPERFAMILY SSF55486 254 581 1.19E-82 T 06-07-2017 LK06_RS18195 92cad5cfc2a99d7939f71bf3b987906e 582 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 120 167 1.9E-16 T 06-07-2017 IPR011096 FTP domain LK06_RS18195 92cad5cfc2a99d7939f71bf3b987906e 582 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 395 411 2.7E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS18195 92cad5cfc2a99d7939f71bf3b987906e 582 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 416 427 2.7E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS18195 92cad5cfc2a99d7939f71bf3b987906e 582 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 483 499 2.7E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS18195 92cad5cfc2a99d7939f71bf3b987906e 582 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 359 379 2.7E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS18195 92cad5cfc2a99d7939f71bf3b987906e 582 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 407 581 1.6E-55 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 LK06_RS18195 92cad5cfc2a99d7939f71bf3b987906e 582 Gene3D G3DSA:3.10.170.10 256 408 9.3E-44 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS18195 92cad5cfc2a99d7939f71bf3b987906e 582 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 256 403 4.4E-46 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS18195 92cad5cfc2a99d7939f71bf3b987906e 582 Gene3D G3DSA:1.10.390.10 409 581 1.3E-54 T 06-07-2017 LK06_RS06560 6ba091f36f0b04ea3f04ff58eff70cd3 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 272 6.0E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06560 6ba091f36f0b04ea3f04ff58eff70cd3 279 SUPERFAMILY SSF161098 8 279 8.9E-67 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06560 6ba091f36f0b04ea3f04ff58eff70cd3 279 Gene3D G3DSA:1.10.3720.10 5 267 3.6E-59 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS29380 ffc42e70512c4c0b4ceadb01620974a7 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 62 4.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS29380 ffc42e70512c4c0b4ceadb01620974a7 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 70 93 4.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS29380 ffc42e70512c4c0b4ceadb01620974a7 236 SUPERFAMILY SSF46689 36 107 1.28E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS29380 ffc42e70512c4c0b4ceadb01620974a7 236 Gene3D G3DSA:1.10.10.60 38 89 1.4E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS29380 ffc42e70512c4c0b4ceadb01620974a7 236 Gene3D G3DSA:1.10.357.10 90 222 8.1E-13 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS29380 ffc42e70512c4c0b4ceadb01620974a7 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 49 92 1.6E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS29380 ffc42e70512c4c0b4ceadb01620974a7 236 ProSitePatterns PS01081 TetR-type HTH domain signature. 61 92 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS25420 454404ab647069a68040774f08a6339e 263 SUPERFAMILY SSF54593 149 260 6.31E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS25420 454404ab647069a68040774f08a6339e 263 Gene3D G3DSA:3.10.180.10 146 261 5.0E-30 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS25420 454404ab647069a68040774f08a6339e 263 Gene3D G3DSA:3.10.180.10 18 131 6.0E-29 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS25420 454404ab647069a68040774f08a6339e 263 SUPERFAMILY SSF54593 19 131 1.05E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS20105 137d0308804e777263ac9d064fa569bc 317 SUPERFAMILY SSF88713 121 316 2.04E-41 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS20105 137d0308804e777263ac9d064fa569bc 317 Pfam PF01522 Polysaccharide deacetylase 131 250 3.0E-28 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS20105 137d0308804e777263ac9d064fa569bc 317 Gene3D G3DSA:3.20.20.370 122 317 5.8E-41 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS22155 634bf922db70e3a811b092b72242cd20 568 SUPERFAMILY SSF53756 191 501 1.88E-56 T 06-07-2017 LK06_RS22155 634bf922db70e3a811b092b72242cd20 568 SUPERFAMILY SSF53756 2 89 1.88E-56 T 06-07-2017 LK06_RS22155 634bf922db70e3a811b092b72242cd20 568 Pfam PF13692 Glycosyl transferases group 1 313 469 7.4E-24 T 06-07-2017 LK06_RS22155 634bf922db70e3a811b092b72242cd20 568 Pfam PF11997 Domain of unknown function (DUF3492) 2 284 2.4E-28 T 06-07-2017 IPR022622 Domain of unknown function DUF3492 LK06_RS22155 634bf922db70e3a811b092b72242cd20 568 Gene3D G3DSA:3.40.50.2000 306 482 4.0E-20 T 06-07-2017 LK06_RS23440 9bd107e7ecda33d55c2b4090adbd8344 318 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 15 312 3.0E-106 T 06-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS23440 9bd107e7ecda33d55c2b4090adbd8344 318 Pfam PF03308 ArgK protein 20 280 4.5E-98 T 06-07-2017 LK06_RS23440 9bd107e7ecda33d55c2b4090adbd8344 318 Gene3D G3DSA:3.40.50.300 46 251 9.3E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23440 9bd107e7ecda33d55c2b4090adbd8344 318 SUPERFAMILY SSF52540 3 311 1.74E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01680 e4255b5c664111bd42c0d01d7ac01a94 299 SMART SM01232 149 241 5.6E-29 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 LK06_RS01680 e4255b5c664111bd42c0d01d7ac01a94 299 SUPERFAMILY SSF46946 148 231 1.7E-24 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 LK06_RS01680 e4255b5c664111bd42c0d01d7ac01a94 299 SUPERFAMILY SSF57716 245 283 5.99E-11 T 06-07-2017 LK06_RS01680 e4255b5c664111bd42c0d01d7ac01a94 299 SUPERFAMILY SSF81624 2 158 2.35E-21 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS01680 e4255b5c664111bd42c0d01d7ac01a94 299 SMART SM00898 2 135 1.8E-18 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS01680 e4255b5c664111bd42c0d01d7ac01a94 299 Pfam PF06827 Zinc finger found in FPG and IleRS 256 283 7.0E-8 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 LK06_RS01680 e4255b5c664111bd42c0d01d7ac01a94 299 Gene3D G3DSA:1.10.8.50 150 284 1.2E-36 T 06-07-2017 LK06_RS01680 e4255b5c664111bd42c0d01d7ac01a94 299 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 149 233 8.7E-21 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 LK06_RS01680 e4255b5c664111bd42c0d01d7ac01a94 299 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 99 5.2E-13 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS01680 e4255b5c664111bd42c0d01d7ac01a94 299 Gene3D G3DSA:3.20.190.10 2 149 1.3E-17 T 06-07-2017 LK06_RS03920 968bbd2be332c539cf2d9d39fca4b54d 444 Pfam PF03471 Transporter associated domain 363 432 5.2E-16 T 06-07-2017 IPR005170 Transporter-associated domain LK06_RS03920 968bbd2be332c539cf2d9d39fca4b54d 444 Gene3D G3DSA:3.30.465.10 332 432 8.6E-23 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS03920 968bbd2be332c539cf2d9d39fca4b54d 444 SUPERFAMILY SSF54631 213 345 1.01E-24 T 06-07-2017 LK06_RS03920 968bbd2be332c539cf2d9d39fca4b54d 444 SMART SM01091 357 434 1.7E-16 T 06-07-2017 IPR005170 Transporter-associated domain LK06_RS03920 968bbd2be332c539cf2d9d39fca4b54d 444 Pfam PF00571 CBS domain 289 337 7.8E-4 T 06-07-2017 IPR000644 CBS domain LK06_RS03920 968bbd2be332c539cf2d9d39fca4b54d 444 Pfam PF01595 Domain of unknown function DUF21 11 202 2.3E-37 T 06-07-2017 IPR002550 Domain of unknown function DUF21 LK06_RS03920 968bbd2be332c539cf2d9d39fca4b54d 444 Gene3D G3DSA:3.10.580.10 210 331 4.8E-17 T 06-07-2017 LK06_RS03920 968bbd2be332c539cf2d9d39fca4b54d 444 SUPERFAMILY SSF56176 362 435 3.0E-15 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS24775 3c7e207ff26f6a2ca2ca7275a206167e 155 ProSitePatterns PS01319 Ribosome-binding factor A signature. 76 97 - T 06-07-2017 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 LK06_RS24775 3c7e207ff26f6a2ca2ca7275a206167e 155 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 97 1.0E-42 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 LK06_RS24775 3c7e207ff26f6a2ca2ca7275a206167e 155 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 112 8.0E-23 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 LK06_RS24775 3c7e207ff26f6a2ca2ca7275a206167e 155 Gene3D G3DSA:3.30.300.20 3 118 4.4E-36 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS24775 3c7e207ff26f6a2ca2ca7275a206167e 155 SUPERFAMILY SSF89919 2 113 3.92E-31 T 06-07-2017 IPR023799 Ribosome-binding factor A domain LK06_RS24775 3c7e207ff26f6a2ca2ca7275a206167e 155 Pfam PF02033 Ribosome-binding factor A 6 110 1.3E-25 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 LK06_RS24775 3c7e207ff26f6a2ca2ca7275a206167e 155 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 117 20.517 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 LK06_RS14615 6b7bf6a6a2c4012db2af96838cd8f3a9 182 SUPERFAMILY SSF53271 5 178 1.44E-37 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS14615 6b7bf6a6a2c4012db2af96838cd8f3a9 182 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 170 2.5E-36 T 06-07-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS14615 6b7bf6a6a2c4012db2af96838cd8f3a9 182 Gene3D G3DSA:3.40.50.2020 8 179 2.4E-49 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS14615 6b7bf6a6a2c4012db2af96838cd8f3a9 182 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 182 25.355 T 06-07-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS14615 6b7bf6a6a2c4012db2af96838cd8f3a9 182 Pfam PF00156 Phosphoribosyl transferase domain 58 161 3.8E-12 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 Gene3D G3DSA:1.20.970.10 3 69 1.4E-28 T 06-07-2017 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 Gene3D G3DSA:3.90.1170.30 320 410 1.3E-30 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 337 409 8.9E-24 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 Pfam PF00591 Glycosyl transferase family, a/b domain 79 286 1.0E-31 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 112 127 - T 06-07-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 6 408 5.8E-169 T 06-07-2017 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 Gene3D G3DSA:3.40.1030.10 72 318 3.3E-107 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 SUPERFAMILY SSF54680 324 426 2.35E-25 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 SUPERFAMILY SSF52418 71 318 1.15E-79 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 SUPERFAMILY SSF47648 3 71 8.37E-21 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 PIRSF PIRSF000478 2 425 4.3E-152 T 06-07-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 SMART SM00941 336 410 7.7E-35 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS20705 27c2712ce2ae9b71cfb0a5b0983100cd 427 Pfam PF02885 Glycosyl transferase family, helical bundle domain 8 68 1.2E-18 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 24 231 1.8E-63 T 06-07-2017 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 249 548 4.0E-103 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 Pfam PF01336 OB-fold nucleic acid binding domain 659 736 1.3E-8 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 Gene3D G3DSA:3.30.930.10 750 1088 1.7E-96 T 06-07-2017 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 623 1093 34.041 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 SUPERFAMILY SSF50249 615 746 3.67E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 PRINTS PR00982 Lysyl-tRNA synthetase signature 835 848 3.1E-28 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 PRINTS PR00982 Lysyl-tRNA synthetase signature 853 870 3.1E-28 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 PRINTS PR00982 Lysyl-tRNA synthetase signature 976 992 3.1E-28 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 PRINTS PR00982 Lysyl-tRNA synthetase signature 790 800 3.1E-28 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 PRINTS PR00982 Lysyl-tRNA synthetase signature 806 822 3.1E-28 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 656 1091 1.9E-129 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 Gene3D G3DSA:2.40.50.140 618 746 1.3E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 SUPERFAMILY SSF55681 753 1091 3.78E-98 T 06-07-2017 LK06_RS01645 5246f39012d1f9081d2d3a300db94588 1093 Pfam PF00152 tRNA synthetases class II (D, K and N) 755 1090 2.5E-64 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 PRINTS PR00364 Disease resistance protein signature 423 437 4.6E-6 T 06-07-2017 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 PRINTS PR00364 Disease resistance protein signature 508 522 4.6E-6 T 06-07-2017 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 PRINTS PR00364 Disease resistance protein signature 346 361 4.6E-6 T 06-07-2017 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SUPERFAMILY SSF48452 95 267 1.07E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SUPERFAMILY SSF48452 754 949 1.61E-21 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 Pfam PF13424 Tetratricopeptide repeat 892 961 4.3E-8 T 06-07-2017 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 Pfam PF13424 Tetratricopeptide repeat 810 881 1.7E-12 T 06-07-2017 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SMART SM01043 99 244 1.1E-48 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SUPERFAMILY SSF48452 934 1039 2.74E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 Gene3D G3DSA:3.40.50.300 339 436 1.1E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 Gene3D G3DSA:1.25.40.10 740 1044 1.2E-34 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 Pfam PF03704 Bacterial transcriptional activator domain 99 244 2.8E-41 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 Gene3D G3DSA:1.10.10.10 25 86 3.0E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SUPERFAMILY SSF52540 307 574 2.18E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SMART SM00028 890 923 7.6 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SMART SM00028 810 843 71.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SMART SM00028 850 883 0.0074 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SMART SM00028 769 802 46.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SMART SM00028 970 1003 24.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 Pfam PF13374 Tetratricopeptide repeat 973 1003 0.0016 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SUPERFAMILY SSF46894 2 90 1.08E-10 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 SMART SM00862 16 92 7.0E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS28485 725a9b454a9a376c3d8caf152be8d3f8 1056 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 90 6.5E-8 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS02645 0f246b71a0e4e881ba7246fc24b979e1 440 Pfam PF00668 Condensation domain 9 286 7.1E-44 T 06-07-2017 IPR001242 Condensation domain LK06_RS02645 0f246b71a0e4e881ba7246fc24b979e1 440 SUPERFAMILY SSF52777 174 425 8.0E-36 T 06-07-2017 LK06_RS02645 0f246b71a0e4e881ba7246fc24b979e1 440 SUPERFAMILY SSF52777 7 167 3.67E-31 T 06-07-2017 LK06_RS26700 dd87037ae087942bd5f89882b01bcbfb 192 SUPERFAMILY SSF53056 4 191 6.15E-54 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS26700 dd87037ae087942bd5f89882b01bcbfb 192 Gene3D G3DSA:3.40.1050.10 9 190 3.3E-59 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS26700 dd87037ae087942bd5f89882b01bcbfb 192 Pfam PF00484 Carbonic anhydrase 30 179 6.8E-42 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS26700 dd87037ae087942bd5f89882b01bcbfb 192 SMART SM00947 22 183 1.3E-56 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS26700 dd87037ae087942bd5f89882b01bcbfb 192 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 34 41 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS26700 dd87037ae087942bd5f89882b01bcbfb 192 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 78 98 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS30860 40a90f38727ce2b41b20938d02659007 346 Pfam PF07720 Tetratricopeptide repeat 257 275 0.017 T 06-07-2017 IPR011716 Tetratricopeptide TPR-3 LK06_RS30860 40a90f38727ce2b41b20938d02659007 346 Pfam PF13424 Tetratricopeptide repeat 169 239 9.1E-12 T 06-07-2017 LK06_RS30860 40a90f38727ce2b41b20938d02659007 346 SUPERFAMILY SSF48452 70 283 8.72E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS30860 40a90f38727ce2b41b20938d02659007 346 Gene3D G3DSA:1.25.40.10 87 303 5.6E-22 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS17585 f2b597341acde58195dd25deaefc643a 259 Gene3D G3DSA:1.10.10.10 123 221 1.8E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17585 f2b597341acde58195dd25deaefc643a 259 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 1.2E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS17585 f2b597341acde58195dd25deaefc643a 259 SUPERFAMILY SSF46894 126 220 3.59E-30 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS17585 f2b597341acde58195dd25deaefc643a 259 SMART SM00862 145 219 2.2E-30 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 109 120 - T 06-07-2017 IPR018215 ClpP, Ser active site LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 Gene3D G3DSA:3.90.226.10 23 213 5.6E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 PRINTS PR00127 Clp protease catalytic subunit P signature 188 207 1.5E-43 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 PRINTS PR00127 Clp protease catalytic subunit P signature 130 149 1.5E-43 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 PRINTS PR00127 Clp protease catalytic subunit P signature 109 126 1.5E-43 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 PRINTS PR00127 Clp protease catalytic subunit P signature 38 53 1.5E-43 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 PRINTS PR00127 Clp protease catalytic subunit P signature 78 98 1.5E-43 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 SUPERFAMILY SSF52096 30 214 7.28E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 22 213 39.815 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 131 144 - T 06-07-2017 IPR033135 ClpP, histidine active site LK06_RS09910 77669538c3a02ca4f1a1a5813fb72cc4 221 Pfam PF00574 Clp protease 32 212 1.3E-76 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA LK06_RS23235 68100b9ad8cf05a3a4330ed6068e8183 74 SUPERFAMILY SSF143800 1 67 3.92E-24 T 06-07-2017 LK06_RS23235 68100b9ad8cf05a3a4330ed6068e8183 74 PRINTS PR01249 Ribosomal protein L31 signature 47 65 1.6E-20 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS23235 68100b9ad8cf05a3a4330ed6068e8183 74 PRINTS PR01249 Ribosomal protein L31 signature 32 47 1.6E-20 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS23235 68100b9ad8cf05a3a4330ed6068e8183 74 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.6E-20 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS23235 68100b9ad8cf05a3a4330ed6068e8183 74 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 28.713 T 06-07-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS23235 68100b9ad8cf05a3a4330ed6068e8183 74 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 4.9E-33 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS23235 68100b9ad8cf05a3a4330ed6068e8183 74 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS23235 68100b9ad8cf05a3a4330ed6068e8183 74 Pfam PF01197 Ribosomal protein L31 2 66 6.1E-30 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 2.0E-9 T 06-07-2017 LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 409 428 2.0E-9 T 06-07-2017 LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 2.0E-9 T 06-07-2017 LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 85 107 2.0E-9 T 06-07-2017 LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 Pfam PF07690 Major Facilitator Superfamily 26 418 7.8E-56 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 Gene3D G3DSA:1.20.1250.20 272 430 9.7E-18 T 06-07-2017 LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 433 3.0E-79 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 Gene3D G3DSA:1.20.1250.20 18 206 4.8E-33 T 06-07-2017 LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 SUPERFAMILY SSF103473 482 510 1.96E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 SUPERFAMILY SSF103473 257 428 1.96E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS07960 909051f31c6663b5b435ee0b7a756068 541 SUPERFAMILY SSF103473 12 206 1.96E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS00285 ede309801950fcc34c94f35ebc573314 219 Pfam PF02254 TrkA-N domain 4 118 5.6E-23 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LK06_RS00285 ede309801950fcc34c94f35ebc573314 219 Gene3D G3DSA:3.40.50.720 1 142 8.1E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00285 ede309801950fcc34c94f35ebc573314 219 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.3E-13 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS00285 ede309801950fcc34c94f35ebc573314 219 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.3E-13 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS00285 ede309801950fcc34c94f35ebc573314 219 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.3E-13 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS00285 ede309801950fcc34c94f35ebc573314 219 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.3E-13 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS00285 ede309801950fcc34c94f35ebc573314 219 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.3E-13 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS00285 ede309801950fcc34c94f35ebc573314 219 SUPERFAMILY SSF116726 142 214 8.11E-5 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS00285 ede309801950fcc34c94f35ebc573314 219 SUPERFAMILY SSF51735 1 141 8.49E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23865 c9b64535d7a7bffb8a1dd8fc541d28ad 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 9.1E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS23865 c9b64535d7a7bffb8a1dd8fc541d28ad 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 9.1E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS23865 c9b64535d7a7bffb8a1dd8fc541d28ad 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 9.1E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS23865 c9b64535d7a7bffb8a1dd8fc541d28ad 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 9.1E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS23865 c9b64535d7a7bffb8a1dd8fc541d28ad 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 9.1E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS23865 c9b64535d7a7bffb8a1dd8fc541d28ad 232 Gene3D G3DSA:3.40.50.720 8 219 1.7E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23865 c9b64535d7a7bffb8a1dd8fc541d28ad 232 SUPERFAMILY SSF51735 6 219 2.12E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23865 c9b64535d7a7bffb8a1dd8fc541d28ad 232 Pfam PF00106 short chain dehydrogenase 8 192 2.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS23865 c9b64535d7a7bffb8a1dd8fc541d28ad 232 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 204 5.6E-4 T 06-07-2017 LK06_RS23865 c9b64535d7a7bffb8a1dd8fc541d28ad 232 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS29090 fe19f45f93080fc991a350b69d8cf042 405 Pfam PF00144 Beta-lactamase 63 384 1.5E-50 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS29090 fe19f45f93080fc991a350b69d8cf042 405 SUPERFAMILY SSF56601 53 383 1.26E-55 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS29090 fe19f45f93080fc991a350b69d8cf042 405 Gene3D G3DSA:3.40.710.10 54 398 2.2E-56 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS07025 084234e0ebd1c2b1a3937f31fe81f112 318 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 113 1.2E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS07025 084234e0ebd1c2b1a3937f31fe81f112 318 SUPERFAMILY SSF56645 1 120 1.09E-15 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS07025 084234e0ebd1c2b1a3937f31fe81f112 318 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 182 310 9.6E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS07025 084234e0ebd1c2b1a3937f31fe81f112 318 Gene3D G3DSA:1.10.540.10 1 114 1.4E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS07025 084234e0ebd1c2b1a3937f31fe81f112 318 SUPERFAMILY SSF47203 182 313 2.74E-34 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS07025 084234e0ebd1c2b1a3937f31fe81f112 318 Gene3D G3DSA:1.20.140.10 185 313 1.0E-30 T 06-07-2017 LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 Gene3D G3DSA:3.30.565.10 312 457 1.3E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 SUPERFAMILY SSF47384 227 301 2.55E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 1.4E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 417 1.4E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 1.4E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 437 1.4E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 SMART SM00388 240 307 1.1E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 Gene3D G3DSA:1.10.287.130 232 299 9.9E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 SUPERFAMILY SSF55874 314 457 4.98E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 457 1.4E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 305 9.5E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS23330 8eea32860b99bba4038ef844362ae4a8 487 SMART SM00387 349 460 2.8E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14625 c6330e9f4dc2a634a41b294b86938a66 290 SUPERFAMILY SSF55961 1 139 1.76E-17 T 06-07-2017 LK06_RS14625 c6330e9f4dc2a634a41b294b86938a66 290 Gene3D G3DSA:3.30.530.20 1 140 3.3E-22 T 06-07-2017 IPR023393 START-like domain LK06_RS14625 c6330e9f4dc2a634a41b294b86938a66 290 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 136 1.3E-7 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 SUPERFAMILY SSF48256 3 429 2.36E-159 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 PRINTS PR00143 Citrate synthase signature 241 269 3.6E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 PRINTS PR00143 Citrate synthase signature 380 394 3.6E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 PRINTS PR00143 Citrate synthase signature 219 234 3.6E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 PRINTS PR00143 Citrate synthase signature 297 317 3.6E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 PRINTS PR00143 Citrate synthase signature 165 178 3.6E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 PRINTS PR00143 Citrate synthase signature 360 376 3.6E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 PIRSF PIRSF001369 37 429 8.1E-157 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 Pfam PF00285 Citrate synthase, C-terminal domain 46 412 3.3E-134 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 Gene3D G3DSA:1.10.580.10 52 281 1.4E-94 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 ProSitePatterns PS00480 Citrate synthase signature. 304 316 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 14 423 4.6E-185 T 06-07-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 LK06_RS10610 4be1591def8e2fa1f8e492bf733341cd 429 Gene3D G3DSA:1.10.230.10 282 374 6.0E-36 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 LK06_RS02415 70847296eca5feff84f4999bb1756593 264 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 17 188 2.7E-20 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS02415 70847296eca5feff84f4999bb1756593 264 SUPERFAMILY SSF52266 11 197 1.28E-33 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS02415 70847296eca5feff84f4999bb1756593 264 Gene3D G3DSA:3.40.50.1110 12 198 4.6E-32 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS25165 26cfa0ff99391ccfc4174007c63c5d40 454 SMART SM00098 48 454 2.5E-156 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 LK06_RS25165 26cfa0ff99391ccfc4174007c63c5d40 454 ProSitePatterns PS00123 Alkaline phosphatase active site. 102 110 - T 06-07-2017 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 LK06_RS25165 26cfa0ff99391ccfc4174007c63c5d40 454 Gene3D G3DSA:3.40.720.10 16 453 6.1E-121 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 LK06_RS25165 26cfa0ff99391ccfc4174007c63c5d40 454 PRINTS PR00113 Alkaline phosphatase signature 140 160 3.2E-36 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 LK06_RS25165 26cfa0ff99391ccfc4174007c63c5d40 454 PRINTS PR00113 Alkaline phosphatase signature 47 67 3.2E-36 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 LK06_RS25165 26cfa0ff99391ccfc4174007c63c5d40 454 PRINTS PR00113 Alkaline phosphatase signature 102 117 3.2E-36 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 LK06_RS25165 26cfa0ff99391ccfc4174007c63c5d40 454 PRINTS PR00113 Alkaline phosphatase signature 302 331 3.2E-36 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 LK06_RS25165 26cfa0ff99391ccfc4174007c63c5d40 454 PRINTS PR00113 Alkaline phosphatase signature 202 212 3.2E-36 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 LK06_RS25165 26cfa0ff99391ccfc4174007c63c5d40 454 SUPERFAMILY SSF53649 37 453 2.8E-116 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 LK06_RS25165 26cfa0ff99391ccfc4174007c63c5d40 454 Pfam PF00245 Alkaline phosphatase 47 407 4.6E-105 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 LK06_RS32160 33137e243ab8e9645f072b2ff4b3b5c4 121 Pfam PF00665 Integrase core domain 1 63 2.2E-9 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 LK06_RS32160 33137e243ab8e9645f072b2ff4b3b5c4 121 Gene3D G3DSA:3.30.420.10 2 63 4.2E-9 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS32160 33137e243ab8e9645f072b2ff4b3b5c4 121 SUPERFAMILY SSF53098 2 65 5.01E-11 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS01135 1f9b6b5b1d319bcf0b979919cc90a214 603 Gene3D G3DSA:2.80.10.50 395 520 2.0E-14 T 06-07-2017 LK06_RS01135 1f9b6b5b1d319bcf0b979919cc90a214 603 Gene3D G3DSA:1.10.10.10 115 171 7.2E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01135 1f9b6b5b1d319bcf0b979919cc90a214 603 SMART SM00458 389 520 1.0E-4 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS01135 1f9b6b5b1d319bcf0b979919cc90a214 603 SUPERFAMILY SSF50370 393 519 7.16E-18 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS01135 1f9b6b5b1d319bcf0b979919cc90a214 603 SUPERFAMILY SSF88659 116 170 6.11E-5 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01135 1f9b6b5b1d319bcf0b979919cc90a214 603 Pfam PF00652 Ricin-type beta-trefoil lectin domain 394 517 4.0E-16 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS30300 8fd59522a1c2051ced1456bb727b6d57 133 Pfam PF01047 MarR family 58 100 5.8E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS30300 8fd59522a1c2051ced1456bb727b6d57 133 Gene3D G3DSA:1.10.10.10 11 129 1.7E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30300 8fd59522a1c2051ced1456bb727b6d57 133 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 108 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site LK06_RS30300 8fd59522a1c2051ced1456bb727b6d57 133 SMART SM00347 30 130 2.7E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS30300 8fd59522a1c2051ced1456bb727b6d57 133 SUPERFAMILY SSF46785 10 129 1.95E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30300 8fd59522a1c2051ced1456bb727b6d57 133 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 3.3E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS30300 8fd59522a1c2051ced1456bb727b6d57 133 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 3.3E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17010 20eee938601493d8984e5a2315bb53b1 105 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 101 2.0E-48 T 06-07-2017 IPR024412 Lsr2 LK06_RS17010 20eee938601493d8984e5a2315bb53b1 105 Pfam PF11774 Lsr2 2 104 1.4E-37 T 06-07-2017 IPR024412 Lsr2 LK06_RS00610 279b28bbd59b682fc40e868eeeabb8b0 206 Pfam PF06042 Nucleotidyltransferase 31 193 5.9E-52 T 06-07-2017 IPR009267 Putative nucleotidyltransferase LK06_RS31575 60d007c00cdce371089e5158cb7d19c4 275 Pfam PF13359 DDE superfamily endonuclease 109 267 5.4E-30 T 06-07-2017 IPR027806 Harbinger transposase-derived nuclease domain LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 9.3E-17 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 SUPERFAMILY SSF46785 1 60 1.25E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.1E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.1E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.1E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 SMART SM00344 1 108 2.9E-38 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 1.7E-18 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 SUPERFAMILY SSF54909 61 143 1.07E-17 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 Gene3D G3DSA:3.30.70.920 54 144 2.5E-23 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS13055 2b1618ea3340edc36ea54091c9ca1fb4 151 Gene3D G3DSA:1.10.10.10 1 52 2.9E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26215 6e87024bc0aa3b11bdc050250f63d866 384 SUPERFAMILY SSF51905 272 353 1.53E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26215 6e87024bc0aa3b11bdc050250f63d866 384 SUPERFAMILY SSF51905 8 176 1.53E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26215 6e87024bc0aa3b11bdc050250f63d866 384 Gene3D G3DSA:3.50.50.60 273 350 1.2E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26215 6e87024bc0aa3b11bdc050250f63d866 384 Gene3D G3DSA:3.50.50.60 8 182 1.2E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26215 6e87024bc0aa3b11bdc050250f63d866 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 3.1E-18 T 06-07-2017 LK06_RS26215 6e87024bc0aa3b11bdc050250f63d866 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 3.1E-18 T 06-07-2017 LK06_RS26215 6e87024bc0aa3b11bdc050250f63d866 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 3.1E-18 T 06-07-2017 LK06_RS26215 6e87024bc0aa3b11bdc050250f63d866 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 3.1E-18 T 06-07-2017 LK06_RS26215 6e87024bc0aa3b11bdc050250f63d866 384 Pfam PF01494 FAD binding domain 7 347 4.7E-23 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS14095 d2fab518a2f0a29617857a66945b8cda 480 Gene3D G3DSA:1.20.1530.10 25 407 7.7E-136 T 06-07-2017 IPR023171 Na/H antiporter domain LK06_RS14095 d2fab518a2f0a29617857a66945b8cda 480 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 25 410 20.726 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 LK06_RS14095 d2fab518a2f0a29617857a66945b8cda 480 Pfam PF06965 Na+/H+ antiporter 1 28 401 1.4E-133 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 LK06_RS14095 d2fab518a2f0a29617857a66945b8cda 480 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 30 400 3.2E-97 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 LK06_RS02515 b2447e264261745187f1db00a2da13c3 452 Pfam PF03055 Retinal pigment epithelial membrane protein 18 449 1.5E-86 T 06-07-2017 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 LK06_RS29195 af03a07166d66b5f9102c1353d94bef8 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 38 132 6.7E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS29195 af03a07166d66b5f9102c1353d94bef8 408 Gene3D G3DSA:1.10.540.10 27 125 1.2E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS29195 af03a07166d66b5f9102c1353d94bef8 408 Gene3D G3DSA:1.20.140.10 239 389 4.9E-11 T 06-07-2017 LK06_RS29195 af03a07166d66b5f9102c1353d94bef8 408 PIRSF PIRSF016578 17 389 4.7E-17 T 06-07-2017 LK06_RS29195 af03a07166d66b5f9102c1353d94bef8 408 SUPERFAMILY SSF56645 36 243 1.31E-31 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS29195 af03a07166d66b5f9102c1353d94bef8 408 SUPERFAMILY SSF47203 255 393 7.96E-9 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS29195 af03a07166d66b5f9102c1353d94bef8 408 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 260 380 1.2E-5 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain LK06_RS29195 af03a07166d66b5f9102c1353d94bef8 408 Gene3D G3DSA:2.40.110.10 139 238 3.2E-4 T 06-07-2017 LK06_RS18675 a4c115c893d5c9fa4a94e26f2bcdf834 244 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 242 6.9E-40 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS18675 a4c115c893d5c9fa4a94e26f2bcdf834 244 SUPERFAMILY SSF52096 4 242 9.95E-55 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS18675 a4c115c893d5c9fa4a94e26f2bcdf834 244 Gene3D G3DSA:3.90.226.10 8 176 2.5E-39 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS18675 a4c115c893d5c9fa4a94e26f2bcdf834 244 Gene3D G3DSA:1.10.12.10 188 242 3.7E-13 T 06-07-2017 IPR014748 Crontonase, C-terminal LK06_RS14655 2124d22f17b726f258ab603f19a1bc97 313 PIRSF PIRSF001060 1 313 1.9E-84 T 06-07-2017 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 LK06_RS14655 2124d22f17b726f258ab603f19a1bc97 313 SUPERFAMILY SSF53955 110 313 5.91E-68 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS14655 2124d22f17b726f258ab603f19a1bc97 313 Gene3D G3DSA:1.10.530.10 233 313 3.6E-54 T 06-07-2017 LK06_RS14655 2124d22f17b726f258ab603f19a1bc97 313 Gene3D G3DSA:1.10.530.10 112 169 3.6E-54 T 06-07-2017 LK06_RS14655 2124d22f17b726f258ab603f19a1bc97 313 Pfam PF00182 Chitinase class I 113 313 1.0E-46 T 06-07-2017 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 LK06_RS14655 2124d22f17b726f258ab603f19a1bc97 313 SMART SM00495 45 89 6.0E-4 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS14655 2124d22f17b726f258ab603f19a1bc97 313 Gene3D G3DSA:2.10.10.20 41 86 6.8E-6 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS14655 2124d22f17b726f258ab603f19a1bc97 313 Gene3D G3DSA:3.30.20.10 177 232 4.7E-25 T 06-07-2017 LK06_RS03800 41bcb59b4e82420ea848dabfaf8a978a 375 SUPERFAMILY SSF53756 1 366 2.93E-76 T 06-07-2017 LK06_RS03800 41bcb59b4e82420ea848dabfaf8a978a 375 Gene3D G3DSA:3.40.50.2000 171 344 3.8E-28 T 06-07-2017 LK06_RS03800 41bcb59b4e82420ea848dabfaf8a978a 375 Pfam PF13439 Glycosyltransferase Family 4 14 179 1.1E-24 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS03800 41bcb59b4e82420ea848dabfaf8a978a 375 Pfam PF00534 Glycosyl transferases group 1 193 344 1.1E-25 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS04885 4bb2cd9dbb800e75b8774e8ca0413cd4 307 Gene3D G3DSA:1.10.10.10 20 104 4.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04885 4bb2cd9dbb800e75b8774e8ca0413cd4 307 Pfam PF03466 LysR substrate binding domain 107 304 4.4E-43 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS04885 4bb2cd9dbb800e75b8774e8ca0413cd4 307 SUPERFAMILY SSF53850 110 304 2.01E-38 T 06-07-2017 LK06_RS04885 4bb2cd9dbb800e75b8774e8ca0413cd4 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 22 79 1.4E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS04885 4bb2cd9dbb800e75b8774e8ca0413cd4 307 SUPERFAMILY SSF46785 18 128 1.36E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04885 4bb2cd9dbb800e75b8774e8ca0413cd4 307 Gene3D G3DSA:3.40.190.10 110 190 1.4E-16 T 06-07-2017 LK06_RS04885 4bb2cd9dbb800e75b8774e8ca0413cd4 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 47 4.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS04885 4bb2cd9dbb800e75b8774e8ca0413cd4 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 57 4.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS04885 4bb2cd9dbb800e75b8774e8ca0413cd4 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 57 68 4.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS04885 4bb2cd9dbb800e75b8774e8ca0413cd4 307 Gene3D G3DSA:3.40.190.10 191 279 8.3E-16 T 06-07-2017 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 Pfam PF00196 Bacterial regulatory proteins, luxR family 187 242 1.0E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 Gene3D G3DSA:3.40.50.2300 30 154 3.0E-24 T 06-07-2017 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 SUPERFAMILY SSF52172 32 169 1.42E-22 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 ProSitePatterns PS00622 LuxR-type HTH domain signature. 202 229 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 SUPERFAMILY SSF46894 178 247 2.28E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 202 1.2E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 218 230 1.2E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 218 1.2E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 SMART SM00421 185 242 6.0E-26 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 SMART SM00448 32 151 5.3E-18 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 Pfam PF00072 Response regulator receiver domain 34 151 1.1E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS20265 138b60f631ce2a6060a17911fb64dfdd 248 Gene3D G3DSA:1.10.10.10 155 248 6.1E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14995 4859fe854b55de38f6bf62d441136758 112 Gene3D G3DSA:1.10.10.10 6 90 1.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14995 4859fe854b55de38f6bf62d441136758 112 SMART SM00418 11 89 6.4E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS14995 4859fe854b55de38f6bf62d441136758 112 SUPERFAMILY SSF46785 3 89 1.19E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14995 4859fe854b55de38f6bf62d441136758 112 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 3.9E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS14995 4859fe854b55de38f6bf62d441136758 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 2.4E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS14995 4859fe854b55de38f6bf62d441136758 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.4E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS14995 4859fe854b55de38f6bf62d441136758 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.4E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS06890 e9b44dc68fca6b70de2bda41e2d9e9c7 776 PIRSF PIRSF000144 5 765 0.0 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 LK06_RS06890 e9b44dc68fca6b70de2bda41e2d9e9c7 776 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 760 5.7E-290 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 LK06_RS06890 e9b44dc68fca6b70de2bda41e2d9e9c7 776 Pfam PF01568 Molydopterin dinucleotide binding domain 647 753 9.8E-10 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 LK06_RS06890 e9b44dc68fca6b70de2bda41e2d9e9c7 776 SUPERFAMILY SSF53706 58 636 1.57E-146 T 06-07-2017 LK06_RS06890 e9b44dc68fca6b70de2bda41e2d9e9c7 776 Gene3D G3DSA:3.40.50.740 395 633 1.4E-57 T 06-07-2017 LK06_RS06890 e9b44dc68fca6b70de2bda41e2d9e9c7 776 Gene3D G3DSA:3.40.50.740 120 193 1.4E-57 T 06-07-2017 LK06_RS06890 e9b44dc68fca6b70de2bda41e2d9e9c7 776 SUPERFAMILY SSF50692 636 762 1.33E-17 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain LK06_RS06890 e9b44dc68fca6b70de2bda41e2d9e9c7 776 Gene3D G3DSA:2.40.40.20 635 761 1.5E-11 T 06-07-2017 LK06_RS06890 e9b44dc68fca6b70de2bda41e2d9e9c7 776 Gene3D G3DSA:3.40.228.10 194 394 3.6E-54 T 06-07-2017 LK06_RS06890 e9b44dc68fca6b70de2bda41e2d9e9c7 776 Pfam PF00384 Molybdopterin oxidoreductase 120 490 3.2E-30 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 Gene3D G3DSA:3.40.50.150 845 927 1.3E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 Gene3D G3DSA:3.40.50.150 968 1131 1.3E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 988 994 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 Pfam PF04851 Type III restriction enzyme, res subunit 140 346 2.8E-26 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 Pfam PF02384 N-6 DNA Methylase 823 1078 1.4E-6 T 06-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 SUPERFAMILY SSF52540 257 348 5.23E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 SUPERFAMILY SSF52540 454 571 5.23E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 SUPERFAMILY SSF52540 160 217 5.23E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 Pfam PF00271 Helicase conserved C-terminal domain 452 565 2.4E-6 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 Pfam PF13156 Restriction endonuclease 7 122 3.6E-47 T 06-07-2017 LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 Gene3D G3DSA:3.40.50.300 145 243 2.0E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 Gene3D G3DSA:3.40.50.300 276 347 2.0E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 878 892 9.3E-6 T 06-07-2017 LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 843 859 9.3E-6 T 06-07-2017 LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 985 997 9.3E-6 T 06-07-2017 LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 Gene3D G3DSA:3.40.50.300 453 575 5.7E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 SUPERFAMILY SSF53335 756 930 6.66E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 SUPERFAMILY SSF53335 962 1161 6.66E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 SMART SM00487 138 376 1.0E-10 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 SUPERFAMILY SSF52980 31 121 5.9E-10 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 SMART SM00490 469 566 8.3E-4 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS21570 213a6e0371821515eac6fb6d154b6223 1599 Gene3D G3DSA:3.40.1350.10 29 103 7.7E-5 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 LK06_RS18730 5cc0473ebeb0deeb36301b20eab55a24 258 Gene3D G3DSA:3.40.50.300 2 223 5.7E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18730 5cc0473ebeb0deeb36301b20eab55a24 258 SUPERFAMILY SSF52540 5 225 4.02E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18730 5cc0473ebeb0deeb36301b20eab55a24 258 SMART SM00382 30 226 2.2E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS18730 5cc0473ebeb0deeb36301b20eab55a24 258 Pfam PF00005 ABC transporter 23 164 3.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 Pfam PF13625 Helicase conserved C-terminal domain 5 133 2.8E-46 T 06-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 SMART SM00490 422 499 3.2E-13 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 Gene3D G3DSA:3.40.50.300 180 342 5.3E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 Gene3D G3DSA:3.40.50.300 380 527 2.0E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 SUPERFAMILY SSF52540 142 342 3.33E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 SUPERFAMILY SSF52540 386 526 1.78E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 SUPERFAMILY SSF52540 280 353 1.78E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 352 540 9.0E-48 T 06-07-2017 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 474 499 7.3E-35 T 06-07-2017 LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 290 310 7.3E-35 T 06-07-2017 LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 190 212 7.3E-35 T 06-07-2017 LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 355 377 7.3E-35 T 06-07-2017 LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 455 473 7.3E-35 T 06-07-2017 LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 409 431 7.3E-35 T 06-07-2017 LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 SMART SM00487 177 352 4.4E-21 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS18435 aab108fc1356a376a945a2bef454feec 547 Pfam PF04851 Type III restriction enzyme, res subunit 181 325 4.1E-13 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 LK06_RS30490 5040fa19819fd1d3a738ba722f026035 151 Pfam PF02502 Ribose/Galactose Isomerase 13 128 3.5E-28 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 LK06_RS30490 5040fa19819fd1d3a738ba722f026035 151 Gene3D G3DSA:3.40.1400.10 1 145 2.6E-36 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 LK06_RS30490 5040fa19819fd1d3a738ba722f026035 151 SUPERFAMILY SSF89623 1 146 8.76E-35 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 LK06_RS30490 5040fa19819fd1d3a738ba722f026035 151 PIRSF PIRSF005384 1 147 7.3E-34 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 LK06_RS03585 df7bf8f889687a53e264253fbd8e20b6 131 Gene3D G3DSA:1.10.1660.10 4 48 6.4E-7 T 06-07-2017 LK06_RS03585 df7bf8f889687a53e264253fbd8e20b6 131 SUPERFAMILY SSF46955 3 52 1.33E-9 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS03585 df7bf8f889687a53e264253fbd8e20b6 131 Pfam PF12728 Helix-turn-helix domain 4 49 2.0E-9 T 06-07-2017 LK06_RS03585 df7bf8f889687a53e264253fbd8e20b6 131 Pfam PF03459 TOBE domain 66 128 3.3E-17 T 06-07-2017 IPR005116 Transport-associated OB, type 1 LK06_RS03585 df7bf8f889687a53e264253fbd8e20b6 131 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 66 128 3.8E-16 T 06-07-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 LK06_RS03585 df7bf8f889687a53e264253fbd8e20b6 131 SUPERFAMILY SSF50331 66 128 9.72E-17 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal LK06_RS03585 df7bf8f889687a53e264253fbd8e20b6 131 Gene3D G3DSA:2.40.50.100 66 128 3.2E-22 T 06-07-2017 LK06_RS16345 89c872ac71c55324fd3829bcc2b6dc68 251 SUPERFAMILY SSF46785 3 78 8.49E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16345 89c872ac71c55324fd3829bcc2b6dc68 251 Gene3D G3DSA:3.40.1410.10 70 245 1.3E-54 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS16345 89c872ac71c55324fd3829bcc2b6dc68 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 2.4E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS16345 89c872ac71c55324fd3829bcc2b6dc68 251 SMART SM00866 98 242 2.1E-14 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS16345 89c872ac71c55324fd3829bcc2b6dc68 251 SMART SM00345 10 69 8.7E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS16345 89c872ac71c55324fd3829bcc2b6dc68 251 Pfam PF07702 UTRA domain 112 240 1.7E-19 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS16345 89c872ac71c55324fd3829bcc2b6dc68 251 SUPERFAMILY SSF64288 57 248 6.12E-31 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS16345 89c872ac71c55324fd3829bcc2b6dc68 251 Gene3D G3DSA:1.10.10.10 3 69 6.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 Gene3D G3DSA:3.40.50.720 7 256 1.6E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 195 0.0093 T 06-07-2017 LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 3.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 Pfam PF00106 short chain dehydrogenase 9 198 1.9E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 SUPERFAMILY SSF51735 7 254 4.48E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29245 80a793a59cab5c5e7c6e61a9d85a3d5d 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS05385 7dd43d005a05c7465fb1ffe061c4384e 438 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 12 434 5.2E-219 T 06-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 LK06_RS05385 7dd43d005a05c7465fb1ffe061c4384e 438 Pfam PF04209 homogentisate 1,2-dioxygenase 13 434 8.5E-213 T 06-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 LK06_RS05385 7dd43d005a05c7465fb1ffe061c4384e 438 Gene3D G3DSA:2.60.120.10 250 404 1.5E-62 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS05385 7dd43d005a05c7465fb1ffe061c4384e 438 Gene3D G3DSA:2.60.120.10 201 226 2.6E-7 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS05385 7dd43d005a05c7465fb1ffe061c4384e 438 SUPERFAMILY SSF51182 12 437 1.4E-162 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS05385 7dd43d005a05c7465fb1ffe061c4384e 438 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 13 436 72.547 T 06-07-2017 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 LK06_RS14950 c29239c72d50098338c922c0b1a732c5 274 SUPERFAMILY SSF46785 191 273 1.82E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14950 c29239c72d50098338c922c0b1a732c5 274 Pfam PF00027 Cyclic nucleotide-binding domain 75 161 3.7E-17 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain LK06_RS14950 c29239c72d50098338c922c0b1a732c5 274 SMART SM00419 214 265 4.6E-8 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LK06_RS14950 c29239c72d50098338c922c0b1a732c5 274 Gene3D G3DSA:2.60.120.10 51 188 4.5E-32 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS14950 c29239c72d50098338c922c0b1a732c5 274 SMART SM00100 56 177 7.0E-14 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain LK06_RS14950 c29239c72d50098338c922c0b1a732c5 274 Gene3D G3DSA:1.10.10.10 191 273 1.9E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14950 c29239c72d50098338c922c0b1a732c5 274 Pfam PF13545 Crp-like helix-turn-helix domain 194 271 5.0E-16 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LK06_RS14950 c29239c72d50098338c922c0b1a732c5 274 SUPERFAMILY SSF51206 50 186 2.62E-31 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like LK06_RS00950 59825eb7836747e768898f379efc61c3 160 SUPERFAMILY SSF47741 85 151 6.67E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LK06_RS00950 59825eb7836747e768898f379efc61c3 160 Gene3D G3DSA:3.10.20.30 2 75 3.7E-24 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS00950 59825eb7836747e768898f379efc61c3 160 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 60 9.9E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS00950 59825eb7836747e768898f379efc61c3 160 Gene3D G3DSA:1.10.150.120 76 156 1.3E-33 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LK06_RS00950 59825eb7836747e768898f379efc61c3 160 SUPERFAMILY SSF54292 3 79 4.85E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS00950 59825eb7836747e768898f379efc61c3 160 Pfam PF01799 [2Fe-2S] binding domain 74 146 4.9E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 Pfam PF00089 Trypsin 36 269 1.5E-49 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 SUPERFAMILY SSF50494 30 268 4.71E-59 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 79 84 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 Gene3D G3DSA:2.40.10.10 36 75 3.3E-10 T 06-07-2017 LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 227 238 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 Gene3D G3DSA:2.40.10.10 76 140 1.1E-13 T 06-07-2017 LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 Gene3D G3DSA:2.40.10.10 141 269 4.6E-37 T 06-07-2017 LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 132 146 1.3E-11 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 69 84 1.3E-11 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 226 238 1.3E-11 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 LK06_RS25285 8004915566b0f38bf42de29b5ec98dc3 286 SMART SM00020 35 269 2.3E-61 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 LK06_RS18120 577d72ceede086578d68f955a975449f 139 PIRSF PIRSF019455 17 137 2.9E-20 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 LK06_RS18120 577d72ceede086578d68f955a975449f 139 Pfam PF03965 Penicillinase repressor 19 126 1.1E-25 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 LK06_RS18120 577d72ceede086578d68f955a975449f 139 Gene3D G3DSA:1.10.10.10 19 89 1.6E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18120 577d72ceede086578d68f955a975449f 139 SUPERFAMILY SSF46785 20 128 1.82E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 395 2.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 356 2.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 370 2.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 414 2.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 415 6.7E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 SUPERFAMILY SSF47384 179 261 2.16E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 SMART SM00387 304 415 6.1E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 Gene3D G3DSA:1.10.287.130 186 258 7.6E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 SUPERFAMILY SSF158472 143 192 1.02E-8 T 06-07-2017 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 Pfam PF00512 His Kinase A (phospho-acceptor) domain 197 261 3.0E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 SMART SM00304 142 195 6.5E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 Pfam PF00672 HAMP domain 123 192 2.2E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 Gene3D G3DSA:3.30.565.10 264 415 3.9E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 SMART SM00388 196 262 5.0E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25455 67262f2dd83253547fc52f334d296bc5 415 SUPERFAMILY SSF55874 253 415 1.83E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 Gene3D G3DSA:3.30.310.50 372 453 2.3E-22 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 Gene3D G3DSA:3.40.120.10 175 252 7.6E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 133 1.5E-28 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 SUPERFAMILY SSF55957 374 454 7.98E-20 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 SUPERFAMILY SSF53738 264 367 3.57E-28 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 SUPERFAMILY SSF53738 156 258 2.71E-30 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 92 106 4.1E-22 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 207 220 4.1E-22 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 4.1E-22 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 4.1E-22 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 SUPERFAMILY SSF53738 7 122 1.77E-29 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 256 5.7E-25 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 453 1.2E-13 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 Gene3D G3DSA:3.40.120.10 9 134 2.8E-25 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 Gene3D G3DSA:3.40.120.10 253 371 2.6E-35 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS11870 d33a3fb1938850e73af5f4fedb2845c4 454 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 265 371 5.1E-25 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS23015 ffd344a086633a6169208b24749190be 760 Gene3D G3DSA:2.130.10.10 183 445 1.8E-51 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 Gene3D G3DSA:2.130.10.10 446 753 1.7E-51 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 PRINTS PR00320 G protein beta WD-40 repeat signature 442 456 2.4E-6 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat LK06_RS23015 ffd344a086633a6169208b24749190be 760 PRINTS PR00320 G protein beta WD-40 repeat signature 398 412 2.4E-6 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat LK06_RS23015 ffd344a086633a6169208b24749190be 760 PRINTS PR00320 G protein beta WD-40 repeat signature 310 324 2.4E-6 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat LK06_RS23015 ffd344a086633a6169208b24749190be 760 SUPERFAMILY SSF50978 308 582 4.76E-58 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SUPERFAMILY SSF50978 509 739 3.02E-31 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 570 584 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS23015 ffd344a086633a6169208b24749190be 760 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 614 628 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS23015 ffd344a086633a6169208b24749190be 760 SUPERFAMILY SSF50978 176 347 4.39E-27 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 354 368 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS23015 ffd344a086633a6169208b24749190be 760 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 220 234 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS23015 ffd344a086633a6169208b24749190be 760 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 310 324 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS23015 ffd344a086633a6169208b24749190be 760 Pfam PF00400 WD domain, G-beta repeat 284 323 8.4E-5 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 Pfam PF00400 WD domain, G-beta repeat 330 367 0.11 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 Pfam PF00400 WD domain, G-beta repeat 374 411 1.8E-4 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 485 499 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 370 411 7.4E-8 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 457 498 0.87 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 586 627 0.065 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 282 323 2.0E-5 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 237 279 11.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 192 233 0.56 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 673 714 1.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 501 540 0.99 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 414 455 1.7 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 326 367 0.028 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 SMART SM00320 543 583 0.011 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS23015 ffd344a086633a6169208b24749190be 760 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 398 412 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS27755 26280908eae99deb3579e11348e250ac 410 SUPERFAMILY SSF47413 9 66 6.48E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS27755 26280908eae99deb3579e11348e250ac 410 Pfam PF13560 Helix-turn-helix domain 8 64 1.3E-9 T 06-07-2017 LK06_RS27755 26280908eae99deb3579e11348e250ac 410 SMART SM00530 12 66 5.0E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS27755 26280908eae99deb3579e11348e250ac 410 Gene3D G3DSA:1.10.260.40 8 66 3.1E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS27755 26280908eae99deb3579e11348e250ac 410 SUPERFAMILY SSF48452 76 274 1.41E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS27755 26280908eae99deb3579e11348e250ac 410 Gene3D G3DSA:1.25.40.10 187 405 1.5E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS14855 d305a78889940e33701a7a767e879c39 114 SMART SM00421 28 85 6.5E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14855 d305a78889940e33701a7a767e879c39 114 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 31 45 7.5E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14855 d305a78889940e33701a7a767e879c39 114 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 61 73 7.5E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14855 d305a78889940e33701a7a767e879c39 114 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 45 61 7.5E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14855 d305a78889940e33701a7a767e879c39 114 SUPERFAMILY SSF46894 25 84 1.12E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS14855 d305a78889940e33701a7a767e879c39 114 Gene3D G3DSA:1.10.10.10 28 84 3.8E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14855 d305a78889940e33701a7a767e879c39 114 Pfam PF00196 Bacterial regulatory proteins, luxR family 30 84 2.8E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS00530 4ee7eac496f8c1bde47718cbdb49a6e4 505 Pfam PF02310 B12 binding domain 18 127 7.0E-22 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS00530 4ee7eac496f8c1bde47718cbdb49a6e4 505 Gene3D G3DSA:3.80.30.20 185 372 1.4E-24 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe LK06_RS00530 4ee7eac496f8c1bde47718cbdb49a6e4 505 SUPERFAMILY SSF102114 169 382 1.96E-27 T 06-07-2017 LK06_RS00530 4ee7eac496f8c1bde47718cbdb49a6e4 505 SUPERFAMILY SSF52242 23 112 7.69E-7 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS00530 4ee7eac496f8c1bde47718cbdb49a6e4 505 TIGRFAM TIGR04367 HpnR_B12_rSAM: hopanoid C-3 methylase HpnR 1 485 9.5E-259 T 06-07-2017 IPR027564 Hopanoid C-3 methylase HpnR LK06_RS00530 4ee7eac496f8c1bde47718cbdb49a6e4 505 SMART SM00729 184 383 5.1E-15 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS00530 4ee7eac496f8c1bde47718cbdb49a6e4 505 Pfam PF04055 Radical SAM superfamily 188 346 7.7E-14 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS10935 1b7dda5f6b666d46ee68e77563988a9f 468 ProSitePatterns PS00571 Amidases signature. 153 184 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LK06_RS10935 1b7dda5f6b666d46ee68e77563988a9f 468 SUPERFAMILY SSF75304 2 454 1.83E-132 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS10935 1b7dda5f6b666d46ee68e77563988a9f 468 Gene3D G3DSA:3.90.1300.10 2 455 6.2E-134 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS10935 1b7dda5f6b666d46ee68e77563988a9f 468 Pfam PF01425 Amidase 24 446 8.7E-102 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS23455 7ac7348707cc80e44e08122c9da83eff 216 Pfam PF01987 Mitochondrial biogenesis AIM24 7 211 1.6E-34 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS23455 7ac7348707cc80e44e08122c9da83eff 216 Gene3D G3DSA:3.60.160.10 8 211 1.3E-42 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS23455 7ac7348707cc80e44e08122c9da83eff 216 SUPERFAMILY SSF51219 8 213 4.71E-45 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain LK06_RS00170 f1f9bf66adaae6a7776b89afeba6f268 793 PIRSF PIRSF017245 1 793 0.0 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 LK06_RS00170 f1f9bf66adaae6a7776b89afeba6f268 793 Hamap MF_01403 Probable phosphoketolase. 9 793 40.811 T 06-07-2017 IPR023962 Probable phosphoketolase LK06_RS00170 f1f9bf66adaae6a7776b89afeba6f268 793 ProSitePatterns PS60002 Phosphoketolase signature 1. 148 154 - T 06-07-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 LK06_RS00170 f1f9bf66adaae6a7776b89afeba6f268 793 SUPERFAMILY SSF52518 380 592 1.53E-22 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS00170 f1f9bf66adaae6a7776b89afeba6f268 793 Pfam PF09364 XFP N-terminal domain 12 388 2.1E-177 T 06-07-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal LK06_RS00170 f1f9bf66adaae6a7776b89afeba6f268 793 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 403 579 1.5E-86 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 LK06_RS00170 f1f9bf66adaae6a7776b89afeba6f268 793 ProSitePatterns PS60003 Phosphoketolase signature 2. 161 179 - T 06-07-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 LK06_RS00170 f1f9bf66adaae6a7776b89afeba6f268 793 Gene3D G3DSA:3.40.50.970 57 259 2.0E-19 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS00170 f1f9bf66adaae6a7776b89afeba6f268 793 SUPERFAMILY SSF52518 10 373 2.49E-69 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS00170 f1f9bf66adaae6a7776b89afeba6f268 793 Pfam PF09363 XFP C-terminal domain 590 791 7.0E-89 T 06-07-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 LK06_RS26235 0a5b2ada2b5aa1b5804823ab937d6f69 602 Gene3D G3DSA:3.40.50.620 231 379 1.5E-64 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS26235 0a5b2ada2b5aa1b5804823ab937d6f69 602 Gene3D G3DSA:3.40.50.620 439 564 1.5E-64 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS26235 0a5b2ada2b5aa1b5804823ab937d6f69 602 Pfam PF00733 Asparagine synthase 234 582 1.1E-68 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 LK06_RS26235 0a5b2ada2b5aa1b5804823ab937d6f69 602 SUPERFAMILY SSF56235 20 219 1.29E-45 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS26235 0a5b2ada2b5aa1b5804823ab937d6f69 602 Gene3D G3DSA:3.60.20.10 2 222 9.2E-50 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS26235 0a5b2ada2b5aa1b5804823ab937d6f69 602 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 515 1.2E-102 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 LK06_RS26235 0a5b2ada2b5aa1b5804823ab937d6f69 602 Pfam PF13537 Glutamine amidotransferase domain 45 166 3.4E-35 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain LK06_RS26235 0a5b2ada2b5aa1b5804823ab937d6f69 602 SUPERFAMILY SSF52402 435 566 1.73E-57 T 06-07-2017 LK06_RS26235 0a5b2ada2b5aa1b5804823ab937d6f69 602 SUPERFAMILY SSF52402 229 375 1.73E-57 T 06-07-2017 LK06_RS26235 0a5b2ada2b5aa1b5804823ab937d6f69 602 PIRSF PIRSF001589 2 598 1.3E-119 T 06-07-2017 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 281 289 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 255 394 1.5E-68 T 06-07-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 SUPERFAMILY SSF55973 3 109 2.51E-44 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 405 56.499 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 1.8E-40 T 06-07-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 404 6.3E-168 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 Pfam PF02772 S-adenosylmethionine synthetase, central domain 130 253 7.0E-42 T 06-07-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 Gene3D G3DSA:3.30.300.10 11 148 2.6E-44 T 06-07-2017 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 PIRSF PIRSF000497 1 406 9.3E-163 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 Gene3D G3DSA:3.30.300.10 266 405 4.1E-70 T 06-07-2017 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 SUPERFAMILY SSF55973 125 253 3.1E-43 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 Gene3D G3DSA:3.30.300.10 149 255 6.7E-37 T 06-07-2017 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 SUPERFAMILY SSF55973 255 405 2.16E-68 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS04075 aad837a1857831f46a880015fcd7586c 407 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 131 141 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LK06_RS02370 d9bd29f054abbad3a5fd1d8c39b4c929 385 TIGRFAM TIGR00433 bioB: biotin synthase 28 321 5.2E-114 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 LK06_RS02370 d9bd29f054abbad3a5fd1d8c39b4c929 385 SUPERFAMILY SSF102114 18 321 7.46E-79 T 06-07-2017 LK06_RS02370 d9bd29f054abbad3a5fd1d8c39b4c929 385 SMART SM00729 55 261 8.2E-39 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS02370 d9bd29f054abbad3a5fd1d8c39b4c929 385 Hamap MF_01694 Biotin synthase [bioB]. 15 323 39.816 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 LK06_RS02370 d9bd29f054abbad3a5fd1d8c39b4c929 385 PIRSF PIRSF001619 4 329 5.4E-107 T 06-07-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 LK06_RS02370 d9bd29f054abbad3a5fd1d8c39b4c929 385 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 232 321 1.4E-14 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 LK06_RS02370 d9bd29f054abbad3a5fd1d8c39b4c929 385 Pfam PF04055 Radical SAM superfamily 65 220 4.5E-14 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS02370 d9bd29f054abbad3a5fd1d8c39b4c929 385 SMART SM00876 232 322 8.6E-33 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 LK06_RS02370 d9bd29f054abbad3a5fd1d8c39b4c929 385 Gene3D G3DSA:3.20.20.70 17 322 7.7E-90 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 Pfam PF00753 Metallo-beta-lactamase superfamily 16 182 1.7E-6 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 SMART SM00849 13 182 2.3E-18 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 SUPERFAMILY SSF56281 10 244 9.66E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 SUPERFAMILY SSF52821 222 352 1.57E-13 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 Pfam PF00581 Rhodanese-like domain 362 444 7.2E-7 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 SMART SM00450 251 351 12.0 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 SMART SM00450 357 450 3.5E-13 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 Gene3D G3DSA:3.40.250.10 255 351 9.0E-7 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 SUPERFAMILY SSF52821 345 451 4.58E-22 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 Gene3D G3DSA:3.60.15.10 10 239 5.1E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS14400 6f32e45417042b025d3617ce60cb984e 454 Gene3D G3DSA:3.40.250.10 352 451 3.6E-18 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS06330 0117d26a8d452847fea078eb71b8a080 423 SUPERFAMILY SSF53383 12 420 1.95E-106 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS06330 0117d26a8d452847fea078eb71b8a080 423 Gene3D G3DSA:3.90.1150.10 21 61 3.3E-30 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS06330 0117d26a8d452847fea078eb71b8a080 423 Gene3D G3DSA:3.90.1150.10 325 421 3.3E-30 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS06330 0117d26a8d452847fea078eb71b8a080 423 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 6 422 5.4E-135 T 06-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 LK06_RS06330 0117d26a8d452847fea078eb71b8a080 423 Pfam PF00202 Aminotransferase class-III 27 418 4.2E-75 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS06330 0117d26a8d452847fea078eb71b8a080 423 Gene3D G3DSA:3.40.640.10 62 318 2.0E-61 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS06330 0117d26a8d452847fea078eb71b8a080 423 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS06330 0117d26a8d452847fea078eb71b8a080 423 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 10 420 5.4E-201 T 06-07-2017 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 LK06_RS32060 0055f201584abe039cd45c0f0554faa8 293 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 5 136 2.7E-20 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain LK06_RS32060 0055f201584abe039cd45c0f0554faa8 293 SUPERFAMILY SSF51197 4 293 3.5E-61 T 06-07-2017 LK06_RS32060 0055f201584abe039cd45c0f0554faa8 293 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 205 273 1.1E-11 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 LK06_RS32060 0055f201584abe039cd45c0f0554faa8 293 PRINTS PR00682 Isopenicillin N synthase signature 245 271 6.7E-7 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 LK06_RS32060 0055f201584abe039cd45c0f0554faa8 293 PRINTS PR00682 Isopenicillin N synthase signature 28 45 6.7E-7 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 LK06_RS32060 0055f201584abe039cd45c0f0554faa8 293 PRINTS PR00682 Isopenicillin N synthase signature 157 173 6.7E-7 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 LK06_RS32060 0055f201584abe039cd45c0f0554faa8 293 Gene3D G3DSA:2.60.120.330 4 293 1.0E-63 T 06-07-2017 IPR027443 Isopenicillin N synthase-like LK06_RS31470 f3d0e701c273ec970ea52ea60e9af238 262 Gene3D G3DSA:3.40.50.1820 30 258 2.7E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS31470 f3d0e701c273ec970ea52ea60e9af238 262 ProSitePatterns PS00724 Stress-induced proteins SRP1/TIP1 family signature. 141 147 - T 06-07-2017 IPR000992 Stress-induced protein SRP1/TIP1 GO:0006950 LK06_RS31470 f3d0e701c273ec970ea52ea60e9af238 262 Pfam PF12697 Alpha/beta hydrolase family 52 248 9.3E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS31470 f3d0e701c273ec970ea52ea60e9af238 262 SUPERFAMILY SSF53474 19 260 1.13E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 Gene3D G3DSA:3.30.70.870 310 387 3.4E-25 T 06-07-2017 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 Gene3D G3DSA:3.30.70.240 419 507 4.5E-21 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 SUPERFAMILY SSF54980 417 512 2.4E-23 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 SUPERFAMILY SSF54980 310 389 1.4E-19 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 Pfam PF03144 Elongation factor Tu domain 2 224 294 3.6E-8 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 Pfam PF06421 GTP-binding protein LepA C-terminus 507 612 2.3E-48 T 06-07-2017 IPR013842 GTP-binding protein LepA, C-terminal LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 Pfam PF00679 Elongation factor G C-terminus 417 497 1.7E-21 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 SUPERFAMILY SSF50447 184 298 4.95E-25 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 192 1.2E-18 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 SMART SM00838 416 500 0.001 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 Pfam PF00009 Elongation factor Tu GTP binding domain 19 200 1.7E-50 T 06-07-2017 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 Hamap MF_00071 Elongation factor 4 [lepA]. 1 616 284.272 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 PRINTS PR00315 GTP-binding elongation factor signature 64 72 4.2E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 PRINTS PR00315 GTP-binding elongation factor signature 93 103 4.2E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 PRINTS PR00315 GTP-binding elongation factor signature 109 120 4.2E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 PRINTS PR00315 GTP-binding elongation factor signature 145 154 4.2E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 PRINTS PR00315 GTP-binding elongation factor signature 21 34 4.2E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 Gene3D G3DSA:2.40.30.10 214 306 7.3E-20 T 06-07-2017 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 TIGRFAM TIGR01393 lepA: elongation factor 4 19 614 7.9E-290 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 SUPERFAMILY SSF52540 14 220 8.63E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09530 f9b3527e9c86a0f316c014cfe1442978 624 Gene3D G3DSA:3.40.50.300 15 213 2.3E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03150 6420ddeb2c70be73cc5062cd5e13b9dd 183 Pfam PF01609 Transposase DDE domain 18 156 7.7E-13 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS02935 db3cf69feb44e2a6c849c2282ebb6a30 454 Pfam PF09852 Predicted membrane protein (DUF2079) 24 450 2.6E-88 T 06-07-2017 IPR018650 Sulfolobus virus STSV1, Orf64 LK06_RS26860 15604ccf78998e0aed902687575f801c 58 Gene3D G3DSA:3.30.390.30 1 56 1.3E-14 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS26860 15604ccf78998e0aed902687575f801c 58 SUPERFAMILY SSF55424 1 56 1.08E-13 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 LK06_RS26860 15604ccf78998e0aed902687575f801c 58 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 1 45 3.3E-11 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 SUPERFAMILY SSF53706 5 541 4.06E-163 T 06-07-2017 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 SUPERFAMILY SSF53706 569 602 4.06E-163 T 06-07-2017 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 Gene3D G3DSA:2.20.25.90 5 55 2.6E-17 T 06-07-2017 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 SUPERFAMILY SSF50692 563 711 1.22E-49 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 55 1.8E-14 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 Gene3D G3DSA:2.40.40.20 551 711 6.7E-57 T 06-07-2017 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 SMART SM00926 3 57 3.4E-11 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 Pfam PF01568 Molydopterin dinucleotide binding domain 600 707 7.9E-35 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 Gene3D G3DSA:3.40.228.10 134 312 5.2E-53 T 06-07-2017 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 Pfam PF00384 Molybdopterin oxidoreductase 60 484 8.4E-71 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 Gene3D G3DSA:3.40.50.740 60 132 3.5E-66 T 06-07-2017 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 Gene3D G3DSA:3.40.50.740 372 525 3.5E-66 T 06-07-2017 LK06_RS09205 be0f1f1c21580325c13d72e8aec244ad 732 Gene3D G3DSA:3.40.50.740 313 337 3.5E-66 T 06-07-2017 LK06_RS03600 db5b5255fca7f66c0c8f49c1b89e2a62 369 Pfam PF00005 ABC transporter 41 181 4.5E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS03600 db5b5255fca7f66c0c8f49c1b89e2a62 369 SUPERFAMILY SSF50331 256 367 6.59E-17 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal LK06_RS03600 db5b5255fca7f66c0c8f49c1b89e2a62 369 Pfam PF03459 TOBE domain 306 365 5.3E-12 T 06-07-2017 IPR005116 Transport-associated OB, type 1 LK06_RS03600 db5b5255fca7f66c0c8f49c1b89e2a62 369 SMART SM00382 48 231 2.3E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS03600 db5b5255fca7f66c0c8f49c1b89e2a62 369 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS03600 db5b5255fca7f66c0c8f49c1b89e2a62 369 Gene3D G3DSA:3.40.50.300 41 254 1.4E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03600 db5b5255fca7f66c0c8f49c1b89e2a62 369 Gene3D G3DSA:2.40.50.100 294 362 2.7E-16 T 06-07-2017 LK06_RS03600 db5b5255fca7f66c0c8f49c1b89e2a62 369 SUPERFAMILY SSF52540 36 256 1.82E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09820 5ddb8e27698eafe01fd17967b6fd91d3 250 SUPERFAMILY SSF53448 1 242 9.24E-32 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS09820 5ddb8e27698eafe01fd17967b6fd91d3 250 Pfam PF12804 MobA-like NTP transferase domain 3 138 1.4E-9 T 06-07-2017 IPR025877 MobA-like NTP transferase LK06_RS09820 5ddb8e27698eafe01fd17967b6fd91d3 250 Gene3D G3DSA:3.90.550.10 2 245 1.9E-32 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS28690 5ddb8e27698eafe01fd17967b6fd91d3 250 SUPERFAMILY SSF53448 1 242 9.24E-32 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS28690 5ddb8e27698eafe01fd17967b6fd91d3 250 Pfam PF12804 MobA-like NTP transferase domain 3 138 1.4E-9 T 06-07-2017 IPR025877 MobA-like NTP transferase LK06_RS28690 5ddb8e27698eafe01fd17967b6fd91d3 250 Gene3D G3DSA:3.90.550.10 2 245 1.9E-32 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS08480 78a16f589df1a67e233046a1b4f3c36a 345 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 127 339 2.0E-33 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 LK06_RS08480 78a16f589df1a67e233046a1b4f3c36a 345 SUPERFAMILY SSF53187 124 342 2.04E-31 T 06-07-2017 LK06_RS08480 78a16f589df1a67e233046a1b4f3c36a 345 SMART SM00646 211 339 8.2E-15 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 LK06_RS08480 78a16f589df1a67e233046a1b4f3c36a 345 Gene3D G3DSA:3.40.630.40 124 342 3.5E-33 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 LK06_RS08225 888e0803e8e5a3ae056a0ccdec4be6bf 291 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 38 291 1.1E-94 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 LK06_RS08225 888e0803e8e5a3ae056a0ccdec4be6bf 291 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 30 290 42.123 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 LK06_RS08225 888e0803e8e5a3ae056a0ccdec4be6bf 291 SUPERFAMILY SSF51621 29 289 5.89E-100 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS08225 888e0803e8e5a3ae056a0ccdec4be6bf 291 Gene3D G3DSA:3.20.20.60 28 290 9.1E-111 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS08225 888e0803e8e5a3ae056a0ccdec4be6bf 291 Pfam PF02548 Ketopantoate hydroxymethyltransferase 29 284 1.7E-107 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 LK06_RS08225 888e0803e8e5a3ae056a0ccdec4be6bf 291 PIRSF PIRSF000388 22 291 1.1E-108 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 LK06_RS19935 1e1c6506d443ee89692cbdcefa140c11 408 SMART SM00257 353 402 4.1E-8 T 06-07-2017 IPR018392 LysM domain LK06_RS19935 1e1c6506d443ee89692cbdcefa140c11 408 SUPERFAMILY SSF53955 41 122 7.99E-27 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS19935 1e1c6506d443ee89692cbdcefa140c11 408 Gene3D G3DSA:3.10.350.10 352 401 1.9E-8 T 06-07-2017 IPR018392 LysM domain LK06_RS19935 1e1c6506d443ee89692cbdcefa140c11 408 Pfam PF01476 LysM domain 354 401 2.9E-6 T 06-07-2017 IPR018392 LysM domain LK06_RS19935 1e1c6506d443ee89692cbdcefa140c11 408 SUPERFAMILY SSF54106 352 401 3.01E-5 T 06-07-2017 IPR018392 LysM domain LK06_RS19935 1e1c6506d443ee89692cbdcefa140c11 408 Gene3D G3DSA:1.10.530.10 19 122 3.0E-37 T 06-07-2017 LK06_RS19935 1e1c6506d443ee89692cbdcefa140c11 408 Pfam PF06737 Transglycosylase-like domain 41 116 1.0E-27 T 06-07-2017 IPR010618 Transglycosylase-like LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 PRINTS PR00147 DNA photolyase signature 332 350 7.1E-26 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 PRINTS PR00147 DNA photolyase signature 141 157 7.1E-26 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 PRINTS PR00147 DNA photolyase signature 371 385 7.1E-26 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 PRINTS PR00147 DNA photolyase signature 312 328 7.1E-26 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 SUPERFAMILY SSF52425 4 182 2.49E-37 T 06-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 332 351 - T 06-07-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 Gene3D G3DSA:1.10.579.10 271 452 2.5E-66 T 06-07-2017 LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 Gene3D G3DSA:3.40.50.620 2 147 1.1E-37 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 312 324 - T 06-07-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 Pfam PF00875 DNA photolyase 4 163 3.3E-38 T 06-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 SUPERFAMILY SSF48173 188 453 9.68E-92 T 06-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 Gene3D G3DSA:1.25.40.80 148 270 1.0E-30 T 06-07-2017 LK06_RS01940 2dbc0b8517b8313b7910add9efe664b7 458 Pfam PF03441 FAD binding domain of DNA photolyase 263 450 6.8E-70 T 06-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 LK06_RS21415 2509375ea6ea321d460fc73ac62c2ae8 315 SMART SM00244 83 247 1.7E-11 T 06-07-2017 IPR001107 Band 7 domain LK06_RS21415 2509375ea6ea321d460fc73ac62c2ae8 315 SUPERFAMILY SSF117892 118 249 3.92E-9 T 06-07-2017 IPR001107 Band 7 domain LK06_RS21415 2509375ea6ea321d460fc73ac62c2ae8 315 Pfam PF01145 SPFH domain / Band 7 family 87 257 1.3E-24 T 06-07-2017 IPR001107 Band 7 domain LK06_RS24530 8595de5f096232cdbce57044629613db 360 SUPERFAMILY SSF53850 37 355 3.95E-53 T 06-07-2017 LK06_RS24530 8595de5f096232cdbce57044629613db 360 Pfam PF13416 Bacterial extracellular solute-binding protein 52 328 1.4E-18 T 06-07-2017 LK06_RS24530 8595de5f096232cdbce57044629613db 360 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 36 354 2.8E-69 T 06-07-2017 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 LK06_RS24530 8595de5f096232cdbce57044629613db 360 Gene3D G3DSA:3.40.190.10 290 331 6.1E-30 T 06-07-2017 LK06_RS24530 8595de5f096232cdbce57044629613db 360 Gene3D G3DSA:3.40.190.10 11 134 6.1E-30 T 06-07-2017 LK06_RS24530 8595de5f096232cdbce57044629613db 360 Gene3D G3DSA:3.40.190.10 140 289 2.3E-20 T 06-07-2017 LK06_RS15910 44a91223a0583d29b35ae24b410c7ffb 110 Gene3D G3DSA:3.40.30.10 5 107 1.8E-36 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS15910 44a91223a0583d29b35ae24b410c7ffb 110 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 2.1E-36 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LK06_RS15910 44a91223a0583d29b35ae24b410c7ffb 110 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 LK06_RS15910 44a91223a0583d29b35ae24b410c7ffb 110 SUPERFAMILY SSF52833 3 109 1.57E-36 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS15910 44a91223a0583d29b35ae24b410c7ffb 110 Pfam PF00085 Thioredoxin 6 105 1.1E-31 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 LK06_RS15910 44a91223a0583d29b35ae24b410c7ffb 110 PRINTS PR00421 Thioredoxin family signature 72 83 1.1E-7 T 06-07-2017 LK06_RS15910 44a91223a0583d29b35ae24b410c7ffb 110 PRINTS PR00421 Thioredoxin family signature 24 32 1.1E-7 T 06-07-2017 LK06_RS15910 44a91223a0583d29b35ae24b410c7ffb 110 PRINTS PR00421 Thioredoxin family signature 32 41 1.1E-7 T 06-07-2017 LK06_RS15910 44a91223a0583d29b35ae24b410c7ffb 110 PIRSF PIRSF000077 3 108 1.2E-42 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LK06_RS13120 96f40d2c0b089a3616e1afef1563ba1e 234 Gene3D G3DSA:3.40.50.1240 13 200 4.5E-31 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS13120 96f40d2c0b089a3616e1afef1563ba1e 234 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 14 200 2.5E-34 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS13120 96f40d2c0b089a3616e1afef1563ba1e 234 SMART SM00855 12 164 1.7E-15 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS13120 96f40d2c0b089a3616e1afef1563ba1e 234 SUPERFAMILY SSF53254 11 203 2.75E-36 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS27145 34dfc94c9bdfa1c3f08bd16432f4aa0d 486 Pfam PF00860 Permease family 45 438 1.8E-34 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS25965 9c73912029acba19ccaa96f91622c225 554 SUPERFAMILY SSF81296 444 553 6.3E-23 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS25965 9c73912029acba19ccaa96f91622c225 554 Gene3D G3DSA:3.90.420.10 258 449 2.1E-48 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS25965 9c73912029acba19ccaa96f91622c225 554 SUPERFAMILY SSF56524 258 451 1.7E-52 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS25965 9c73912029acba19ccaa96f91622c225 554 Gene3D G3DSA:2.60.40.650 450 553 6.7E-20 T 06-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 LK06_RS25965 9c73912029acba19ccaa96f91622c225 554 Pfam PF00174 Oxidoreductase molybdopterin binding domain 275 427 5.3E-34 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS01345 690ce2552395b4c9867573df88f9af6a 293 Gene3D G3DSA:3.40.50.720 1 202 5.1E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01345 690ce2552395b4c9867573df88f9af6a 293 Pfam PF13460 NAD(P)H-binding 7 77 2.4E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01345 690ce2552395b4c9867573df88f9af6a 293 SUPERFAMILY SSF51735 1 282 9.96E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01345 690ce2552395b4c9867573df88f9af6a 293 Gene3D G3DSA:3.90.25.10 203 281 4.5E-7 T 06-07-2017 LK06_RS26645 6a80eddfba18aceb7abfe0526efdd370 489 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 15 466 2.5E-66 T 06-07-2017 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LK06_RS26645 6a80eddfba18aceb7abfe0526efdd370 489 Pfam PF01593 Flavin containing amine oxidoreductase 23 465 5.7E-51 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 LK06_RS26645 6a80eddfba18aceb7abfe0526efdd370 489 SUPERFAMILY SSF54373 308 417 1.84E-27 T 06-07-2017 LK06_RS26645 6a80eddfba18aceb7abfe0526efdd370 489 Gene3D G3DSA:3.40.50.720 17 54 1.0E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26645 6a80eddfba18aceb7abfe0526efdd370 489 SUPERFAMILY SSF51905 434 466 7.51E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26645 6a80eddfba18aceb7abfe0526efdd370 489 SUPERFAMILY SSF51905 16 324 7.51E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26645 6a80eddfba18aceb7abfe0526efdd370 489 Gene3D G3DSA:3.90.660.20 245 417 3.0E-39 T 06-07-2017 IPR027418 Protoporphyrinogen oxidase, C-terminal domain KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LK06_RS26645 6a80eddfba18aceb7abfe0526efdd370 489 Gene3D G3DSA:1.10.3110.10 125 207 5.5E-21 T 06-07-2017 LK06_RS15420 2c4ac0d1dc021bf3e6c3bb525874f243 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 1.1E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS15420 2c4ac0d1dc021bf3e6c3bb525874f243 326 SUPERFAMILY SSF51735 111 287 8.74E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15420 2c4ac0d1dc021bf3e6c3bb525874f243 326 Pfam PF00107 Zinc-binding dehydrogenase 151 266 1.5E-30 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS15420 2c4ac0d1dc021bf3e6c3bb525874f243 326 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 323 8.5E-141 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 LK06_RS15420 2c4ac0d1dc021bf3e6c3bb525874f243 326 SUPERFAMILY SSF50129 1 140 1.83E-39 T 06-07-2017 IPR011032 GroES-like LK06_RS15420 2c4ac0d1dc021bf3e6c3bb525874f243 326 SMART SM00829 10 323 2.4E-47 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS15420 2c4ac0d1dc021bf3e6c3bb525874f243 326 Gene3D G3DSA:3.90.180.10 1 146 1.3E-49 T 06-07-2017 IPR011032 GroES-like LK06_RS15420 2c4ac0d1dc021bf3e6c3bb525874f243 326 Gene3D G3DSA:3.40.50.720 147 259 1.0E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS10775 c86c0fd3147e717171a8951956ba891c 188 Pfam PF01184 GPR1/FUN34/yaaH family 10 169 2.9E-10 T 06-07-2017 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 PRINTS PR00046 Major sigma-70 factor signature 228 243 1.1E-6 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 PRINTS PR00046 Major sigma-70 factor signature 211 223 1.1E-6 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 PRINTS PR00046 Major sigma-70 factor signature 65 78 1.1E-6 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 Pfam PF04542 Sigma-70 region 2 41 110 3.4E-18 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 SUPERFAMILY SSF88659 114 189 1.7E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 Pfam PF04545 Sigma-70, region 4 207 256 1.4E-16 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 Gene3D G3DSA:1.10.10.10 200 258 5.6E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 Gene3D G3DSA:1.10.10.10 110 164 8.7E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 Pfam PF04539 Sigma-70 region 3 121 175 3.6E-8 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 SUPERFAMILY SSF88659 186 258 1.87E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 258 4.0E-32 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 35 258 5.4E-84 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 Gene3D G3DSA:1.10.601.10 18 108 5.1E-20 T 06-07-2017 LK06_RS31005 f68c1c8e7182cb677a4ab5ae85394614 263 SUPERFAMILY SSF88946 32 111 2.35E-26 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22730 2efc831ed1990b881b3b120d3f11b987 364 Pfam PF00877 NlpC/P60 family 253 342 1.4E-19 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS22730 2efc831ed1990b881b3b120d3f11b987 364 SUPERFAMILY SSF54001 236 349 1.28E-32 T 06-07-2017 LK06_RS22730 2efc831ed1990b881b3b120d3f11b987 364 Gene3D G3DSA:3.90.1720.10 236 351 9.5E-38 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 409 3.8E-114 T 06-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 SUPERFAMILY SSF53633 4 244 3.14E-71 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 Pfam PF01842 ACT domain 272 316 2.2E-7 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 06-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 Pfam PF13840 ACT domain 344 405 5.4E-13 T 06-07-2017 IPR027795 GATS-like ACT domain LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 SUPERFAMILY SSF55021 254 332 7.55E-18 T 06-07-2017 LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 SUPERFAMILY SSF55021 336 412 9.81E-22 T 06-07-2017 LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 PIRSF PIRSF000726 57 417 4.3E-124 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 Gene3D G3DSA:3.40.1160.10 3 244 1.4E-70 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 Pfam PF00696 Amino acid kinase family 3 231 6.8E-55 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS14490 b6efaba87e1e07e383a1b534a510e1ca 425 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 409 3.0E-123 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS12465 51992633a15b0438a7ec3ba90416cde6 95 Gene3D G3DSA:1.20.5.1030 37 94 3.5E-22 T 06-07-2017 LK06_RS12465 51992633a15b0438a7ec3ba90416cde6 95 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 40 95 3.2E-22 T 06-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 LK06_RS12465 51992633a15b0438a7ec3ba90416cde6 95 Hamap MF_00422 Protein translocase subunit SecE [secE]. 37 92 13.113 T 06-07-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LK06_RS12465 51992633a15b0438a7ec3ba90416cde6 95 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 42 70 - T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LK06_RS12465 51992633a15b0438a7ec3ba90416cde6 95 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 41 89 6.1E-19 T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LK06_RS07625 3c2d865f4dacb95f7ba59d356e405b6d 270 SUPERFAMILY SSF46626 14 129 1.03E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 LK06_RS07625 3c2d865f4dacb95f7ba59d356e405b6d 270 SUPERFAMILY SSF46626 125 218 4.36E-26 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 LK06_RS07625 3c2d865f4dacb95f7ba59d356e405b6d 270 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 143 217 2.2E-12 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 LK06_RS07625 3c2d865f4dacb95f7ba59d356e405b6d 270 Gene3D G3DSA:1.10.760.10 155 220 1.9E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 LK06_RS07625 3c2d865f4dacb95f7ba59d356e405b6d 270 PIRSF PIRSF000007 1 264 3.3E-127 T 06-07-2017 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 LK06_RS07625 3c2d865f4dacb95f7ba59d356e405b6d 270 Gene3D G3DSA:1.10.760.10 48 127 1.0E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 LK06_RS07625 3c2d865f4dacb95f7ba59d356e405b6d 270 Pfam PF00034 Cytochrome c 50 126 1.2E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 LK06_RS07625 3c2d865f4dacb95f7ba59d356e405b6d 270 Gene3D G3DSA:1.10.760.10 128 154 5.1E-4 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 LK06_RS19650 308a1098a6fdf79224bddaa66b8834ec 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 4.2E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19650 308a1098a6fdf79224bddaa66b8834ec 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 4.2E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19650 308a1098a6fdf79224bddaa66b8834ec 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 4.2E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19650 308a1098a6fdf79224bddaa66b8834ec 158 SUPERFAMILY SSF46785 14 152 5.3E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19650 308a1098a6fdf79224bddaa66b8834ec 158 Gene3D G3DSA:1.10.10.10 11 152 5.3E-41 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19650 308a1098a6fdf79224bddaa66b8834ec 158 Pfam PF01047 MarR family 46 104 6.5E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19650 308a1098a6fdf79224bddaa66b8834ec 158 SMART SM00347 39 145 2.3E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 Gene3D G3DSA:1.20.150.20 384 512 6.5E-52 T 06-07-2017 LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 1.4E-239 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 SUPERFAMILY SSF52540 100 382 1.82E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 513 48.357 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 SUPERFAMILY SSF47917 384 512 2.46E-46 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 Gene3D G3DSA:3.40.50.300 99 383 1.0E-108 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 96 5.3E-14 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 1.5E-47 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 SUPERFAMILY SSF50615 27 98 1.41E-21 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 2.3E-67 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 Gene3D G3DSA:2.40.30.20 5 97 1.0E-27 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 LK06_RS23295 a725f285ec2f65895434c3c09447b991 530 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 2.3E-149 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 06-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 PIRSF PIRSF000532 1 339 1.5E-116 T 06-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 Gene3D G3DSA:3.40.50.450 1 212 4.0E-73 T 06-07-2017 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 3.4E-74 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 3.4E-74 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 3.4E-74 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 3.4E-74 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 3.4E-74 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 3.4E-74 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 3.4E-74 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 3.4E-74 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 3.4E-74 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 SUPERFAMILY SSF53784 1 332 1.7E-116 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 Pfam PF00365 Phosphofructokinase 2 297 8.9E-101 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS02250 8955a9f61aedd121618c9c153870e020 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 340 42.65 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 LK06_RS23880 098de36b3d80e304eba41f51c7f8bfff 746 SUPERFAMILY SSF55073 313 462 2.04E-43 T 06-07-2017 IPR029787 Nucleotide cyclase LK06_RS23880 098de36b3d80e304eba41f51c7f8bfff 746 Gene3D G3DSA:3.30.70.270 310 471 1.9E-48 T 06-07-2017 LK06_RS23880 098de36b3d80e304eba41f51c7f8bfff 746 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 462 4.8E-34 T 06-07-2017 IPR000160 GGDEF domain LK06_RS23880 098de36b3d80e304eba41f51c7f8bfff 746 Gene3D G3DSA:3.20.20.450 484 729 5.7E-92 T 06-07-2017 IPR001633 EAL domain LK06_RS23880 098de36b3d80e304eba41f51c7f8bfff 746 Pfam PF00990 Diguanylate cyclase, GGDEF domain 310 462 2.5E-40 T 06-07-2017 IPR000160 GGDEF domain LK06_RS23880 098de36b3d80e304eba41f51c7f8bfff 746 SMART SM00267 302 468 1.7E-44 T 06-07-2017 IPR000160 GGDEF domain LK06_RS23880 098de36b3d80e304eba41f51c7f8bfff 746 SMART SM00052 478 722 1.1E-103 T 06-07-2017 IPR001633 EAL domain LK06_RS23880 098de36b3d80e304eba41f51c7f8bfff 746 Pfam PF00563 EAL domain 485 715 7.8E-72 T 06-07-2017 IPR001633 EAL domain LK06_RS23880 098de36b3d80e304eba41f51c7f8bfff 746 SUPERFAMILY SSF141868 484 730 1.7E-83 T 06-07-2017 IPR001633 EAL domain LK06_RS18655 ab514ff6bb4dbfce8f66754f83bb1c15 532 Pfam PF01039 Carboxyl transferase domain 48 519 5.9E-135 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS18655 ab514ff6bb4dbfce8f66754f83bb1c15 532 SUPERFAMILY SSF52096 273 524 3.65E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS18655 ab514ff6bb4dbfce8f66754f83bb1c15 532 Gene3D G3DSA:3.90.226.10 274 521 4.6E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS18655 ab514ff6bb4dbfce8f66754f83bb1c15 532 Gene3D G3DSA:3.90.226.10 27 265 1.4E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS18655 ab514ff6bb4dbfce8f66754f83bb1c15 532 SUPERFAMILY SSF52096 22 262 1.36E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS00620 97e8c22da9ba34ee87195de1ac6209e9 301 SUPERFAMILY SSF51430 14 298 2.88E-65 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS00620 97e8c22da9ba34ee87195de1ac6209e9 301 Pfam PF00248 Aldo/keto reductase family 19 295 2.1E-50 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS00620 97e8c22da9ba34ee87195de1ac6209e9 301 PRINTS PR00069 Aldo-keto reductase signature 152 169 8.8E-11 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS00620 97e8c22da9ba34ee87195de1ac6209e9 301 PRINTS PR00069 Aldo-keto reductase signature 230 254 8.8E-11 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS00620 97e8c22da9ba34ee87195de1ac6209e9 301 PRINTS PR00069 Aldo-keto reductase signature 53 77 8.8E-11 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS00620 97e8c22da9ba34ee87195de1ac6209e9 301 Gene3D G3DSA:3.20.20.100 14 298 2.0E-62 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS07900 e9bf6665b80ec17434e7a43dcf9d5975 89 Pfam PF00550 Phosphopantetheine attachment site 13 81 7.4E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS07900 e9bf6665b80ec17434e7a43dcf9d5975 89 Gene3D G3DSA:1.10.1200.10 10 87 4.2E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS07900 e9bf6665b80ec17434e7a43dcf9d5975 89 SUPERFAMILY SSF47336 10 88 4.06E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS07900 e9bf6665b80ec17434e7a43dcf9d5975 89 ProSitePatterns PS00012 Phosphopantetheine attachment site. 41 56 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS04940 9516bc4155ed4cb6f493a75f29f58be1 135 SUPERFAMILY SSF103196 3 121 1.19E-27 T 06-07-2017 LK06_RS04940 9516bc4155ed4cb6f493a75f29f58be1 135 SMART SM00960 9 100 2.1E-24 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS04940 9516bc4155ed4cb6f493a75f29f58be1 135 Gene3D G3DSA:3.30.450.30 8 127 8.9E-22 T 06-07-2017 LK06_RS04940 9516bc4155ed4cb6f493a75f29f58be1 135 Pfam PF03259 Roadblock/LC7 domain 9 100 2.3E-23 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS04555 2241f59044b6f1945d7475c96c418142 490 SUPERFAMILY SSF56112 25 274 2.83E-61 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS04555 2241f59044b6f1945d7475c96c418142 490 Gene3D G3DSA:1.10.510.10 112 320 5.3E-38 T 06-07-2017 LK06_RS04555 2241f59044b6f1945d7475c96c418142 490 SMART SM00220 29 281 2.4E-44 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS04555 2241f59044b6f1945d7475c96c418142 490 Gene3D G3DSA:3.30.200.20 21 105 8.8E-17 T 06-07-2017 LK06_RS04555 2241f59044b6f1945d7475c96c418142 490 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 35 57 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS04555 2241f59044b6f1945d7475c96c418142 490 Pfam PF00069 Protein kinase domain 30 273 2.6E-39 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS04555 2241f59044b6f1945d7475c96c418142 490 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 147 159 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 PRINTS PR00132 Glycosyl hydrolase family 2 signature 481 496 2.5E-32 T 06-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 PRINTS PR00132 Glycosyl hydrolase family 2 signature 328 346 2.5E-32 T 06-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 PRINTS PR00132 Glycosyl hydrolase family 2 signature 297 311 2.5E-32 T 06-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 PRINTS PR00132 Glycosyl hydrolase family 2 signature 403 418 2.5E-32 T 06-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 PRINTS PR00132 Glycosyl hydrolase family 2 signature 134 149 2.5E-32 T 06-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 SUPERFAMILY SSF51445 288 569 9.6E-88 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 37 206 2.8E-37 T 06-07-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 338 363 - T 06-07-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 Gene3D G3DSA:3.20.20.80 287 569 4.4E-95 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 288 574 5.6E-103 T 06-07-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 Pfam PF16353 Domain of unknown function(DUF4981) 584 671 1.4E-24 T 06-07-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 Pfam PF02929 Beta galactosidase small chain 699 950 5.1E-55 T 06-07-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 Gene3D G3DSA:2.60.40.320 196 285 2.8E-12 T 06-07-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 403 417 - T 06-07-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 Gene3D G3DSA:2.60.120.260 30 195 2.5E-61 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 SUPERFAMILY SSF74650 686 951 2.2E-70 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 SUPERFAMILY SSF49303 567 674 2.95E-29 T 06-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 Gene3D G3DSA:2.60.40.320 572 675 2.3E-29 T 06-07-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 Gene3D G3DSA:2.70.98.10 715 952 1.1E-70 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 SUPERFAMILY SSF49785 21 206 5.53E-53 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 SMART SM01038 693 952 5.4E-84 T 06-07-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 LK06_RS27055 e82b2cb0b40dcd73c64676895939cd75 958 SUPERFAMILY SSF49303 210 287 1.44E-10 T 06-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 LK06_RS01855 674f41ca59bd15e3f1545cf16f6bd215 276 Pfam PF13560 Helix-turn-helix domain 20 72 4.9E-11 T 06-07-2017 LK06_RS01855 674f41ca59bd15e3f1545cf16f6bd215 276 SUPERFAMILY SSF47413 18 72 1.63E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS01855 674f41ca59bd15e3f1545cf16f6bd215 276 SMART SM00530 23 78 7.7E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS01855 674f41ca59bd15e3f1545cf16f6bd215 276 Gene3D G3DSA:1.10.260.40 20 72 1.7E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS14055 96a6e650261df9ffb47d93017a4b670f 389 Pfam PF00437 Type II/IV secretion system protein 65 340 3.3E-80 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 LK06_RS14055 96a6e650261df9ffb47d93017a4b670f 389 SUPERFAMILY SSF52540 53 367 1.01E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14055 96a6e650261df9ffb47d93017a4b670f 389 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 15 352 4.6E-158 T 06-07-2017 IPR022399 Helicase/secretion neighbourhood ATPase LK06_RS14055 96a6e650261df9ffb47d93017a4b670f 389 Gene3D G3DSA:3.30.450.90 62 157 4.7E-26 T 06-07-2017 LK06_RS14055 96a6e650261df9ffb47d93017a4b670f 389 Gene3D G3DSA:3.40.50.300 164 372 3.8E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21510 c6b41d4555827ea125363584bb72649d 341 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 12 290 1.2E-94 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 LK06_RS21510 c6b41d4555827ea125363584bb72649d 341 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 10 293 36.416 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 LK06_RS21510 c6b41d4555827ea125363584bb72649d 341 Pfam PF02401 LytB protein 12 289 2.3E-88 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 LK06_RS23755 0d05b7c843b45a6dadf3c4af28a43b2e 231 Pfam PF13671 AAA domain 55 177 1.0E-6 T 06-07-2017 LK06_RS23755 0d05b7c843b45a6dadf3c4af28a43b2e 231 SUPERFAMILY SSF52540 55 170 3.84E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23755 0d05b7c843b45a6dadf3c4af28a43b2e 231 Gene3D G3DSA:3.40.50.300 53 180 2.0E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20405 f5578183b99ba5e72656b535151fa46d 314 Pfam PF03466 LysR substrate binding domain 103 299 1.2E-19 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS20405 f5578183b99ba5e72656b535151fa46d 314 Gene3D G3DSA:3.40.190.10 175 271 2.7E-23 T 06-07-2017 LK06_RS20405 f5578183b99ba5e72656b535151fa46d 314 SUPERFAMILY SSF46785 8 86 2.18E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20405 f5578183b99ba5e72656b535151fa46d 314 SUPERFAMILY SSF53850 97 299 6.7E-35 T 06-07-2017 LK06_RS20405 f5578183b99ba5e72656b535151fa46d 314 Gene3D G3DSA:3.40.190.10 95 174 1.7E-20 T 06-07-2017 LK06_RS20405 f5578183b99ba5e72656b535151fa46d 314 Gene3D G3DSA:3.40.190.10 275 301 1.7E-20 T 06-07-2017 LK06_RS20405 f5578183b99ba5e72656b535151fa46d 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 1.3E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS20405 f5578183b99ba5e72656b535151fa46d 314 Gene3D G3DSA:1.10.10.10 2 87 3.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11665 6e858ff9dfa77cfc9a22cd99c2f68030 541 Gene3D G3DSA:3.90.550.10 19 245 1.2E-39 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11665 6e858ff9dfa77cfc9a22cd99c2f68030 541 Pfam PF00535 Glycosyl transferase family 2 21 143 3.1E-26 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS11665 6e858ff9dfa77cfc9a22cd99c2f68030 541 SUPERFAMILY SSF53448 19 233 2.31E-45 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS23495 47a2139ff7dde9a2d4a5e67afddd920d 169 SMART SM00347 48 149 1.6E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS23495 47a2139ff7dde9a2d4a5e67afddd920d 169 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site LK06_RS23495 47a2139ff7dde9a2d4a5e67afddd920d 169 SUPERFAMILY SSF46785 23 159 8.29E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23495 47a2139ff7dde9a2d4a5e67afddd920d 169 Pfam PF01047 MarR family 62 113 3.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS23495 47a2139ff7dde9a2d4a5e67afddd920d 169 Gene3D G3DSA:1.10.10.10 28 159 2.2E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06910 4c57581464290a6c198218e35d9e43e4 595 Pfam PF02653 Branched-chain amino acid transport system / permease component 264 553 8.5E-39 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 296 319 6.9E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 6.9E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 6.9E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 6.9E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.0E-42 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 SUPERFAMILY SSF53671 4 332 8.25E-94 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 Gene3D G3DSA:3.40.50.1370 5 144 2.6E-51 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 332 76.684 T 06-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 4.0E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 4.0E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 310 321 4.0E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 4.0E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 4.0E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 329 2.2E-49 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 Gene3D G3DSA:3.40.50.1370 145 318 8.6E-65 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS29330 5f952f80014d49705a2a048a614bcf00 333 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 9 331 2.5E-124 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS29880 67c1f6f822c0d5bbb0a57ac69e58da4a 222 SUPERFAMILY SSF46689 12 92 2.05E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS29880 67c1f6f822c0d5bbb0a57ac69e58da4a 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS29880 67c1f6f822c0d5bbb0a57ac69e58da4a 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS29880 67c1f6f822c0d5bbb0a57ac69e58da4a 222 Gene3D G3DSA:1.10.357.10 7 187 4.2E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS29880 67c1f6f822c0d5bbb0a57ac69e58da4a 222 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS29880 67c1f6f822c0d5bbb0a57ac69e58da4a 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.8E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17120 10cd7c6783eb23331de2f753e35032a8 500 Pfam PF13520 Amino acid permease 32 470 3.1E-65 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS17120 10cd7c6783eb23331de2f753e35032a8 500 PIRSF PIRSF006060 12 493 7.8E-62 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 Pfam PF00106 short chain dehydrogenase 5 196 8.8E-56 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 185 1.2E-4 T 06-07-2017 LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 SUPERFAMILY SSF51735 3 254 2.21E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 6 255 2.0E-108 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 206 225 2.1E-53 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 10 27 2.1E-53 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 232 251 2.1E-53 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 102 122 2.1E-53 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 167 190 2.1E-53 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 82 99 2.1E-53 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 Gene3D G3DSA:3.40.50.720 1 254 9.2E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26350 cd2c3bed77cb615ee649f2ed4382880d 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS10105 b3cea5027ae760d1e3b3b2f7b74e1ab1 367 SUPERFAMILY SSF82861 99 159 1.18E-8 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 LK06_RS10105 b3cea5027ae760d1e3b3b2f7b74e1ab1 367 SUPERFAMILY SSF50182 161 222 1.28E-9 T 06-07-2017 IPR010920 LSM domain LK06_RS10105 b3cea5027ae760d1e3b3b2f7b74e1ab1 367 Gene3D G3DSA:3.30.70.100 231 316 2.2E-4 T 06-07-2017 LK06_RS10105 b3cea5027ae760d1e3b3b2f7b74e1ab1 367 Gene3D G3DSA:2.30.30.60 176 222 2.9E-9 T 06-07-2017 LK06_RS10105 b3cea5027ae760d1e3b3b2f7b74e1ab1 367 Pfam PF00924 Mechanosensitive ion channel 119 317 2.9E-32 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 LK06_RS10105 b3cea5027ae760d1e3b3b2f7b74e1ab1 367 SUPERFAMILY SSF82689 225 317 4.71E-8 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 LK06_RS17195 7d74987b3b94cfd00febc0ac6883b1bc 97 Pfam PF14408 Ribosomally synthesised peptide in actinomycetes 35 90 1.6E-17 T 06-07-2017 IPR025843 Ribosomally synthesized peptide in Actinomycetes LK06_RS17195 7d74987b3b94cfd00febc0ac6883b1bc 97 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 22 96 1.4E-22 T 06-07-2017 IPR026496 Putative ATP-grasp target RiPP LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 19 187 4.7E-53 T 06-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 SMART SM00482 664 871 1.7E-116 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Gene3D G3DSA:1.10.150.20 203 262 1.6E-24 T 06-07-2017 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Gene3D G3DSA:1.20.1060.10 522 641 3.6E-31 T 06-07-2017 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Gene3D G3DSA:3.40.50.1010 19 202 1.0E-66 T 06-07-2017 IPR029060 PIN domain-like LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 SUPERFAMILY SSF47807 188 296 1.39E-26 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 189 281 2.0E-26 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Gene3D G3DSA:1.10.150.20 691 797 2.0E-31 T 06-07-2017 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 SMART SM00475 16 278 3.0E-141 T 06-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Pfam PF01612 3'-5' exonuclease 366 454 2.2E-4 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 824 840 3.3E-77 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 792 803 3.3E-77 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 633 655 3.3E-77 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 709 722 3.3E-77 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 656 671 3.3E-77 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 733 758 3.3E-77 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 854 867 3.3E-77 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 679 702 3.3E-77 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 770 781 3.3E-77 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Pfam PF00476 DNA polymerase family A 530 904 9.6E-140 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 SMART SM00474 326 497 3.8E-9 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Gene3D G3DSA:3.30.70.370 642 690 2.6E-64 T 06-07-2017 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Gene3D G3DSA:3.30.70.370 798 906 2.6E-64 T 06-07-2017 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 SUPERFAMILY SSF56672 504 905 1.03E-137 T 06-07-2017 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 TIGRFAM TIGR00593 pola: DNA polymerase I 20 906 2.4E-292 T 06-07-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 SUPERFAMILY SSF53098 330 498 6.53E-31 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 SMART SM00279 190 225 3.7E-14 T 06-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 SUPERFAMILY SSF88723 16 187 3.92E-52 T 06-07-2017 IPR029060 PIN domain-like LK06_RS06885 9147a799972264be1e304a6eecfcfd71 908 Gene3D G3DSA:3.30.420.10 329 521 5.8E-51 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS20770 5ecbd4b84ecceea0edfc37f2631dfd7e 228 Pfam PF00072 Response regulator receiver domain 8 115 3.4E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS20770 5ecbd4b84ecceea0edfc37f2631dfd7e 228 Gene3D G3DSA:1.10.10.10 127 226 1.7E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20770 5ecbd4b84ecceea0edfc37f2631dfd7e 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 1.2E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS20770 5ecbd4b84ecceea0edfc37f2631dfd7e 228 SMART SM00448 5 115 4.1E-43 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS20770 5ecbd4b84ecceea0edfc37f2631dfd7e 228 SMART SM00862 148 224 1.0E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS20770 5ecbd4b84ecceea0edfc37f2631dfd7e 228 Gene3D G3DSA:3.40.50.2300 6 126 2.1E-41 T 06-07-2017 LK06_RS20770 5ecbd4b84ecceea0edfc37f2631dfd7e 228 SUPERFAMILY SSF52172 6 175 2.64E-41 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS14875 28b58c6855f5b5467598c09c6e40ea83 112 SMART SM00422 20 88 2.7E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS14875 28b58c6855f5b5467598c09c6e40ea83 112 SUPERFAMILY SSF46955 20 108 1.05E-12 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS14875 28b58c6855f5b5467598c09c6e40ea83 112 Pfam PF13411 MerR HTH family regulatory protein 20 85 4.0E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS14875 28b58c6855f5b5467598c09c6e40ea83 112 Gene3D G3DSA:1.10.1660.10 20 108 7.7E-14 T 06-07-2017 LK06_RS28155 7e507e9ce059a3e60cc025203a3dc615 141 Pfam PF02566 OsmC-like protein 44 135 2.2E-16 T 06-07-2017 IPR003718 OsmC/Ohr family LK06_RS28155 7e507e9ce059a3e60cc025203a3dc615 141 SUPERFAMILY SSF82784 3 132 6.15E-31 T 06-07-2017 IPR003718 OsmC/Ohr family LK06_RS28155 7e507e9ce059a3e60cc025203a3dc615 141 Gene3D G3DSA:3.30.300.20 4 140 7.7E-43 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS28155 7e507e9ce059a3e60cc025203a3dc615 141 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 137 1.0E-51 T 06-07-2017 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 LK06_RS24095 ccafbdcd3432ca48fc923d5fbc16a4b7 1124 SMART SM00387 612 724 1.6E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24095 ccafbdcd3432ca48fc923d5fbc16a4b7 1124 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 615 722 3.8E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24095 ccafbdcd3432ca48fc923d5fbc16a4b7 1124 SMART SM00304 430 500 0.0011 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24095 ccafbdcd3432ca48fc923d5fbc16a4b7 1124 Pfam PF08376 Nitrate and nitrite sensing 126 391 2.2E-41 T 06-07-2017 IPR013587 Nitrate/nitrite sensing protein LK06_RS24095 ccafbdcd3432ca48fc923d5fbc16a4b7 1124 Gene3D G3DSA:3.30.565.10 581 721 1.6E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24095 ccafbdcd3432ca48fc923d5fbc16a4b7 1124 Pfam PF00672 HAMP domain 411 496 6.8E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24095 ccafbdcd3432ca48fc923d5fbc16a4b7 1124 SUPERFAMILY SSF55874 604 721 2.36E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS28425 ea586c41274fc3a6415082191a77689c 466 Gene3D G3DSA:2.60.120.260 329 465 1.3E-44 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS28425 ea586c41274fc3a6415082191a77689c 466 Gene3D G3DSA:2.60.120.200 31 328 6.4E-59 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain LK06_RS28425 ea586c41274fc3a6415082191a77689c 466 SUPERFAMILY SSF49785 329 465 1.63E-34 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS28425 ea586c41274fc3a6415082191a77689c 466 SUPERFAMILY SSF49899 45 315 6.09E-52 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain LK06_RS28425 ea586c41274fc3a6415082191a77689c 466 Pfam PF00722 Glycosyl hydrolases family 16 93 311 2.5E-13 T 06-07-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 LK06_RS28425 ea586c41274fc3a6415082191a77689c 466 Pfam PF03422 Carbohydrate binding module (family 6) 338 465 1.5E-40 T 06-07-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 LK06_RS28425 ea586c41274fc3a6415082191a77689c 466 SMART SM00606 330 466 1.2E-53 T 06-07-2017 IPR006584 Cellulose binding, type IV GO:0030246 LK06_RS22340 ad13dc5008043952987cafffdd1415ca 266 SUPERFAMILY SSF56655 3 264 4.45E-76 T 06-07-2017 LK06_RS22340 ad13dc5008043952987cafffdd1415ca 266 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site LK06_RS22340 ad13dc5008043952987cafffdd1415ca 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 214 238 3.0E-21 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS22340 ad13dc5008043952987cafffdd1415ca 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 3.0E-21 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS22340 ad13dc5008043952987cafffdd1415ca 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 3.0E-21 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS22340 ad13dc5008043952987cafffdd1415ca 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 3.0E-21 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS22340 ad13dc5008043952987cafffdd1415ca 266 Gene3D G3DSA:3.40.190.80 159 264 6.8E-23 T 06-07-2017 LK06_RS22340 ad13dc5008043952987cafffdd1415ca 266 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 8 262 2.5E-91 T 06-07-2017 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 LK06_RS22340 ad13dc5008043952987cafffdd1415ca 266 Pfam PF00459 Inositol monophosphatase family 11 263 1.0E-46 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS22340 ad13dc5008043952987cafffdd1415ca 266 Gene3D G3DSA:3.30.540.10 4 158 3.0E-44 T 06-07-2017 LK06_RS29060 07d5b063331254ce5057fbcd776909fb 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 46 1.6E-9 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS29060 07d5b063331254ce5057fbcd776909fb 343 Pfam PF13407 Periplasmic binding protein domain 71 294 1.1E-26 T 06-07-2017 IPR025997 Periplasmic binding protein LK06_RS29060 07d5b063331254ce5057fbcd776909fb 343 SMART SM00354 4 71 1.6E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS29060 07d5b063331254ce5057fbcd776909fb 343 SUPERFAMILY SSF47413 6 47 1.34E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS29060 07d5b063331254ce5057fbcd776909fb 343 Gene3D G3DSA:3.40.50.2300 101 170 8.6E-12 T 06-07-2017 LK06_RS29060 07d5b063331254ce5057fbcd776909fb 343 Gene3D G3DSA:1.10.260.40 7 46 3.7E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS29060 07d5b063331254ce5057fbcd776909fb 343 Gene3D G3DSA:3.40.50.2300 171 314 1.4E-18 T 06-07-2017 LK06_RS29060 07d5b063331254ce5057fbcd776909fb 343 SUPERFAMILY SSF53822 70 320 3.77E-30 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS25495 70cb704282ad27230ec99ad5aaf18d94 239 Gene3D G3DSA:1.10.10.10 141 238 6.1E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25495 70cb704282ad27230ec99ad5aaf18d94 239 Pfam PF00072 Response regulator receiver domain 15 123 4.7E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25495 70cb704282ad27230ec99ad5aaf18d94 239 SMART SM00862 161 237 6.4E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS25495 70cb704282ad27230ec99ad5aaf18d94 239 SUPERFAMILY SSF52172 12 195 2.99E-41 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS25495 70cb704282ad27230ec99ad5aaf18d94 239 SMART SM00448 13 123 1.6E-42 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25495 70cb704282ad27230ec99ad5aaf18d94 239 Gene3D G3DSA:3.40.50.2300 10 133 3.0E-40 T 06-07-2017 LK06_RS25495 70cb704282ad27230ec99ad5aaf18d94 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 237 9.9E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS24485 886f18a8f6a5e953f5468880b9a2ec1e 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 4.4E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS24485 886f18a8f6a5e953f5468880b9a2ec1e 185 Gene3D G3DSA:1.10.357.10 9 184 5.6E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS24485 886f18a8f6a5e953f5468880b9a2ec1e 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS24485 886f18a8f6a5e953f5468880b9a2ec1e 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS24485 886f18a8f6a5e953f5468880b9a2ec1e 185 SUPERFAMILY SSF46689 3 75 3.84E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS26220 4803e499060df2ad7072c44e461752dd 463 Pfam PF01979 Amidohydrolase family 53 433 3.5E-23 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS26220 4803e499060df2ad7072c44e461752dd 463 Gene3D G3DSA:3.20.20.140 72 420 4.1E-92 T 06-07-2017 LK06_RS26220 4803e499060df2ad7072c44e461752dd 463 Gene3D G3DSA:2.30.40.10 8 71 3.3E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS26220 4803e499060df2ad7072c44e461752dd 463 SUPERFAMILY SSF51338 8 56 1.09E-28 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS26220 4803e499060df2ad7072c44e461752dd 463 SUPERFAMILY SSF51338 380 450 1.09E-28 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS26220 4803e499060df2ad7072c44e461752dd 463 SUPERFAMILY SSF51556 57 380 7.36E-79 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS26220 4803e499060df2ad7072c44e461752dd 463 ProSitePatterns PS00482 Dihydroorotase signature 1. 60 68 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 LK06_RS26220 4803e499060df2ad7072c44e461752dd 463 ProSitePatterns PS00483 Dihydroorotase signature 2. 310 321 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 LK06_RS31735 8dd8cc87266a2e12fb2fed925e5d5347 321 SUPERFAMILY SSF53474 49 304 1.26E-67 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS31735 8dd8cc87266a2e12fb2fed925e5d5347 321 Pfam PF07859 alpha/beta hydrolase fold 81 288 6.6E-70 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 LK06_RS31735 8dd8cc87266a2e12fb2fed925e5d5347 321 Gene3D G3DSA:3.40.50.1820 5 312 2.4E-88 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS07505 1062fe4274e10e5b8dea5c1e2102f913 259 SUPERFAMILY SSF53474 15 121 1.22E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS07505 1062fe4274e10e5b8dea5c1e2102f913 259 SUPERFAMILY SSF53474 174 245 1.22E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS07505 1062fe4274e10e5b8dea5c1e2102f913 259 PIRSF PIRSF017388 1 248 4.1E-75 T 06-07-2017 IPR012354 Esterase/lipase GO:0052689 LK06_RS07505 1062fe4274e10e5b8dea5c1e2102f913 259 Pfam PF12146 Serine aminopeptidase, S33 19 229 7.5E-19 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 LK06_RS07505 1062fe4274e10e5b8dea5c1e2102f913 259 Gene3D G3DSA:3.40.50.1820 13 245 8.7E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30310 7dbec1bd7a81384e5fda59953ff1ab9f 95 Pfam PF12840 Helix-turn-helix domain 5 71 7.8E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30310 7dbec1bd7a81384e5fda59953ff1ab9f 95 SUPERFAMILY SSF46785 4 91 8.18E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30310 7dbec1bd7a81384e5fda59953ff1ab9f 95 Gene3D G3DSA:1.10.10.10 8 93 1.4E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28740 ce01d68081ae356f6a5b85c0bdf56483 684 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 35 655 7.3E-239 T 06-07-2017 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 LK06_RS28740 ce01d68081ae356f6a5b85c0bdf56483 684 SUPERFAMILY SSF48239 66 332 1.73E-72 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS28740 ce01d68081ae356f6a5b85c0bdf56483 684 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 43 328 3.7E-120 T 06-07-2017 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 LK06_RS28740 ce01d68081ae356f6a5b85c0bdf56483 684 Gene3D G3DSA:1.50.10.20 323 653 6.5E-113 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS28740 ce01d68081ae356f6a5b85c0bdf56483 684 SUPERFAMILY SSF48239 325 655 3.22E-103 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS28740 ce01d68081ae356f6a5b85c0bdf56483 684 Gene3D G3DSA:1.50.10.20 64 322 3.3E-67 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS28740 ce01d68081ae356f6a5b85c0bdf56483 684 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 41 653 2.8E-184 T 06-07-2017 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 LK06_RS28740 ce01d68081ae356f6a5b85c0bdf56483 684 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 338 654 1.2E-138 T 06-07-2017 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 LK06_RS04290 a583193fab3e63349f137564437394a5 179 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 46.204 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LK06_RS04290 a583193fab3e63349f137564437394a5 179 SUPERFAMILY SSF53098 2 156 7.08E-45 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS04290 a583193fab3e63349f137564437394a5 179 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 1.2E-53 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LK06_RS04290 a583193fab3e63349f137564437394a5 179 Gene3D G3DSA:3.30.420.10 1 156 2.8E-55 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS04290 a583193fab3e63349f137564437394a5 179 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 06-07-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 LK06_RS04290 a583193fab3e63349f137564437394a5 179 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 155 5.2E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LK06_RS04290 a583193fab3e63349f137564437394a5 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 7.2E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LK06_RS04290 a583193fab3e63349f137564437394a5 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 7.2E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LK06_RS04290 a583193fab3e63349f137564437394a5 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 7.2E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LK06_RS04290 a583193fab3e63349f137564437394a5 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 7.2E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LK06_RS04290 a583193fab3e63349f137564437394a5 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 7.2E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LK06_RS10375 edb89b0b9f3db7357aa555b3042d38af 382 SUPERFAMILY SSF55729 177 342 9.0E-8 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS10375 edb89b0b9f3db7357aa555b3042d38af 382 Pfam PF13480 Acetyltransferase (GNAT) domain 187 333 7.2E-20 T 06-07-2017 LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 Pfam PF00106 short chain dehydrogenase 7 193 2.9E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 SUPERFAMILY SSF51735 5 207 1.93E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 SUPERFAMILY SSF51735 235 269 1.93E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 Gene3D G3DSA:3.40.50.720 6 258 1.6E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 7.6E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.6E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.6E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06100 a999506f2f5ab7e080a42b66793dcb28 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.6E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS22210 6d87f3d32518c98bbad62e69d45bf686 467 Gene3D G3DSA:3.30.70.360 215 368 6.3E-55 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS22210 6d87f3d32518c98bbad62e69d45bf686 467 SUPERFAMILY SSF53187 375 460 2.54E-61 T 06-07-2017 LK06_RS22210 6d87f3d32518c98bbad62e69d45bf686 467 SUPERFAMILY SSF53187 9 204 2.54E-61 T 06-07-2017 LK06_RS22210 6d87f3d32518c98bbad62e69d45bf686 467 Pfam PF01546 Peptidase family M20/M25/M40 88 454 4.4E-32 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 LK06_RS22210 6d87f3d32518c98bbad62e69d45bf686 467 Gene3D G3DSA:3.40.630.10 399 460 5.6E-62 T 06-07-2017 LK06_RS22210 6d87f3d32518c98bbad62e69d45bf686 467 Gene3D G3DSA:3.40.630.10 18 214 5.6E-62 T 06-07-2017 LK06_RS22210 6d87f3d32518c98bbad62e69d45bf686 467 Pfam PF07687 Peptidase dimerisation domain 201 359 1.6E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS27215 19ef08498cb78f7e2dd53656684f28a8 407 Gene3D G3DSA:3.40.50.20 15 118 0.001 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS27215 19ef08498cb78f7e2dd53656684f28a8 407 SMART SM01209 117 285 9.3E-4 T 06-07-2017 LK06_RS27215 19ef08498cb78f7e2dd53656684f28a8 407 Gene3D G3DSA:3.30.470.20 119 387 6.5E-20 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS27215 19ef08498cb78f7e2dd53656684f28a8 407 Pfam PF13535 ATP-grasp domain 153 284 1.6E-14 T 06-07-2017 LK06_RS27215 19ef08498cb78f7e2dd53656684f28a8 407 SUPERFAMILY SSF56059 100 327 6.19E-29 T 06-07-2017 LK06_RS27775 d5cc9093a48ea71b15f79ed2cc25532a 1013 Pfam PF13575 Domain of unknown function (DUF4135) 149 520 7.4E-107 T 06-07-2017 IPR025410 Domain of unknown function DUF4135 LK06_RS27775 d5cc9093a48ea71b15f79ed2cc25532a 1013 Pfam PF05147 Lanthionine synthetase C-like protein 884 1006 1.3E-13 T 06-07-2017 IPR007822 Lanthionine synthetase C-like LK06_RS27775 d5cc9093a48ea71b15f79ed2cc25532a 1013 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 85 819 4.3E-155 T 06-07-2017 IPR017146 Type 2 lantibiotic biosynthesis protein LanM LK06_RS27775 d5cc9093a48ea71b15f79ed2cc25532a 1013 SMART SM01260 661 1006 4.6E-22 T 06-07-2017 IPR007822 Lanthionine synthetase C-like LK06_RS27775 d5cc9093a48ea71b15f79ed2cc25532a 1013 SUPERFAMILY SSF158745 886 1007 1.27E-14 T 06-07-2017 LK06_RS27775 d5cc9093a48ea71b15f79ed2cc25532a 1013 PRINTS PR01955 Frankia sp. LanC-like protein signature 923 943 4.0E-5 T 06-07-2017 IPR020434 LanC-like protein LK06_RS27775 d5cc9093a48ea71b15f79ed2cc25532a 1013 PRINTS PR01955 Frankia sp. LanC-like protein signature 979 996 4.0E-5 T 06-07-2017 IPR020434 LanC-like protein LK06_RS27775 d5cc9093a48ea71b15f79ed2cc25532a 1013 PRINTS PR01955 Frankia sp. LanC-like protein signature 665 680 4.0E-5 T 06-07-2017 IPR020434 LanC-like protein LK06_RS27775 d5cc9093a48ea71b15f79ed2cc25532a 1013 SUPERFAMILY SSF158745 642 742 2.22E-12 T 06-07-2017 LK06_RS13690 28d63a6efd2b9ef60f12e5a29c0aac47 265 Gene3D G3DSA:3.30.420.40 99 263 1.9E-50 T 06-07-2017 LK06_RS13690 28d63a6efd2b9ef60f12e5a29c0aac47 265 SUPERFAMILY SSF53067 129 261 5.18E-36 T 06-07-2017 LK06_RS13690 28d63a6efd2b9ef60f12e5a29c0aac47 265 Pfam PF03309 Type III pantothenate kinase 2 210 6.5E-69 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 LK06_RS13690 28d63a6efd2b9ef60f12e5a29c0aac47 265 Gene3D G3DSA:3.30.420.40 1 68 1.4E-4 T 06-07-2017 LK06_RS13690 28d63a6efd2b9ef60f12e5a29c0aac47 265 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 258 1.5E-75 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 LK06_RS13690 28d63a6efd2b9ef60f12e5a29c0aac47 265 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 262 35.632 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 LK06_RS13690 28d63a6efd2b9ef60f12e5a29c0aac47 265 SUPERFAMILY SSF53067 1 127 1.08E-32 T 06-07-2017 LK06_RS23995 3555a759d27d4c23d2d09ccfc6aec9a2 71 Pfam PF04149 Domain of unknown function (DUF397) 15 65 1.7E-20 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS24790 1b9a4f23e657cf27de14ab9290f45100 315 Pfam PF01687 Riboflavin kinase 188 310 1.1E-31 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 LK06_RS24790 1b9a4f23e657cf27de14ab9290f45100 315 SMART SM00904 187 312 3.0E-46 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 LK06_RS24790 1b9a4f23e657cf27de14ab9290f45100 315 SUPERFAMILY SSF52374 16 180 2.61E-32 T 06-07-2017 LK06_RS24790 1b9a4f23e657cf27de14ab9290f45100 315 Gene3D G3DSA:2.40.30.30 184 314 2.3E-44 T 06-07-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 LK06_RS24790 1b9a4f23e657cf27de14ab9290f45100 315 PIRSF PIRSF004491 1 315 4.0E-94 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS24790 1b9a4f23e657cf27de14ab9290f45100 315 SUPERFAMILY SSF82114 178 312 1.09E-41 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 LK06_RS24790 1b9a4f23e657cf27de14ab9290f45100 315 Gene3D G3DSA:3.40.50.620 3 183 3.7E-62 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS24790 1b9a4f23e657cf27de14ab9290f45100 315 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 310 6.4E-65 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS24790 1b9a4f23e657cf27de14ab9290f45100 315 Pfam PF06574 FAD synthetase 12 157 4.0E-50 T 06-07-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 PIRSF PIRSF006816 5 267 5.0E-59 T 06-07-2017 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 PRINTS PR00410 Phenol hydroxylase reductase family signature 37 49 3.4E-6 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 PRINTS PR00410 Phenol hydroxylase reductase family signature 199 207 3.4E-6 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 PRINTS PR00410 Phenol hydroxylase reductase family signature 111 130 3.4E-6 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 231 261 1.1E-5 T 06-07-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 SUPERFAMILY SSF63380 7 100 3.05E-15 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 Gene3D G3DSA:2.40.30.10 10 90 2.0E-9 T 06-07-2017 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 Gene3D G3DSA:2.10.240.10 231 261 3.2E-7 T 06-07-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 Gene3D G3DSA:3.40.50.80 91 226 3.1E-27 T 06-07-2017 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 SUPERFAMILY SSF52343 107 246 6.42E-29 T 06-07-2017 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 149 160 6.4E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 6.4E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 137 146 6.4E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LK06_RS00330 d530265ca09621b26ea1a8a3085bf4b6 272 Pfam PF00175 Oxidoreductase NAD-binding domain 113 213 1.0E-13 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LK06_RS29745 1322ee7a5f39f20881697617145964c7 356 Pfam PF00891 O-methyltransferase 103 327 4.8E-47 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 LK06_RS29745 1322ee7a5f39f20881697617145964c7 356 Gene3D G3DSA:3.40.50.150 100 330 5.7E-62 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS29745 1322ee7a5f39f20881697617145964c7 356 PIRSF PIRSF005739 2 330 3.3E-42 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 LK06_RS29745 1322ee7a5f39f20881697617145964c7 356 Pfam PF16864 Dimerisation domain 16 86 1.5E-6 T 06-07-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain LK06_RS29745 1322ee7a5f39f20881697617145964c7 356 SUPERFAMILY SSF46785 11 92 8.17E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29745 1322ee7a5f39f20881697617145964c7 356 Gene3D G3DSA:1.10.10.10 13 99 3.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29745 1322ee7a5f39f20881697617145964c7 356 SUPERFAMILY SSF53335 102 327 1.52E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25425 e96c95f700495007bac6e38438a9bfb1 286 ProSitePatterns PS00380 Rhodanese signature 1. 49 60 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 LK06_RS25425 e96c95f700495007bac6e38438a9bfb1 286 SMART SM00450 9 141 1.4E-24 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25425 e96c95f700495007bac6e38438a9bfb1 286 SMART SM00450 158 277 1.0E-14 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25425 e96c95f700495007bac6e38438a9bfb1 286 SUPERFAMILY SSF52821 158 283 1.02E-30 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25425 e96c95f700495007bac6e38438a9bfb1 286 Pfam PF00581 Rhodanese-like domain 170 273 5.3E-11 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25425 e96c95f700495007bac6e38438a9bfb1 286 Pfam PF00581 Rhodanese-like domain 13 136 3.1E-17 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25425 e96c95f700495007bac6e38438a9bfb1 286 Gene3D G3DSA:3.40.250.10 160 283 2.2E-36 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25425 e96c95f700495007bac6e38438a9bfb1 286 Gene3D G3DSA:3.40.250.10 3 154 6.2E-43 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25425 e96c95f700495007bac6e38438a9bfb1 286 SUPERFAMILY SSF52821 5 153 6.42E-34 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS01960 64a4e9a17d872d9c6588dd3efe829c87 722 SUPERFAMILY SSF88713 88 288 1.56E-51 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS01960 64a4e9a17d872d9c6588dd3efe829c87 722 Pfam PF01522 Polysaccharide deacetylase 90 196 5.8E-26 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS01960 64a4e9a17d872d9c6588dd3efe829c87 722 Gene3D G3DSA:3.20.20.370 86 289 4.2E-54 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS01960 64a4e9a17d872d9c6588dd3efe829c87 722 Pfam PF13641 Glycosyltransferase like family 2 363 581 1.0E-35 T 06-07-2017 LK06_RS01960 64a4e9a17d872d9c6588dd3efe829c87 722 Gene3D G3DSA:3.90.550.10 363 596 7.9E-48 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS01960 64a4e9a17d872d9c6588dd3efe829c87 722 SUPERFAMILY SSF53448 363 595 1.04E-58 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS06275 1df5c25496ad04953088fa52424fd55a 411 PIRSF PIRSF036428 1 403 3.0E-108 T 06-07-2017 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 LK06_RS06275 1df5c25496ad04953088fa52424fd55a 411 Gene3D G3DSA:3.30.950.10 102 195 3.0E-14 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06275 1df5c25496ad04953088fa52424fd55a 411 SUPERFAMILY SSF53790 2 194 2.47E-28 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06275 1df5c25496ad04953088fa52424fd55a 411 Gene3D G3DSA:3.40.1010.10 2 101 2.9E-16 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06275 1df5c25496ad04953088fa52424fd55a 411 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 178 2.7E-11 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06275 1df5c25496ad04953088fa52424fd55a 411 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 233 349 4.1E-27 T 06-07-2017 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 LK06_RS06275 1df5c25496ad04953088fa52424fd55a 411 Gene3D G3DSA:3.40.50.150 233 400 2.2E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS06275 1df5c25496ad04953088fa52424fd55a 411 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 5 194 9.4E-43 T 06-07-2017 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 LK06_RS06275 1df5c25496ad04953088fa52424fd55a 411 SUPERFAMILY SSF53335 226 366 1.12E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS00240 862e5899d8f535da8ce784fedf813953 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 23 84 8.2E-7 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS00240 862e5899d8f535da8ce784fedf813953 513 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 12 466 48.353 T 06-07-2017 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 LK06_RS00240 862e5899d8f535da8ce784fedf813953 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 141 357 9.5E-60 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS00240 862e5899d8f535da8ce784fedf813953 513 Gene3D G3DSA:3.40.50.300 86 361 1.8E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00240 862e5899d8f535da8ce784fedf813953 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 348 357 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS00240 862e5899d8f535da8ce784fedf813953 513 SUPERFAMILY SSF52540 88 361 1.59E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29800 0724a781155b1632eaa2eb0839fe005b 487 SUPERFAMILY SSF103473 259 478 6.8E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS29800 0724a781155b1632eaa2eb0839fe005b 487 SUPERFAMILY SSF103473 11 204 6.8E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS29800 0724a781155b1632eaa2eb0839fe005b 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 2.3E-10 T 06-07-2017 LK06_RS29800 0724a781155b1632eaa2eb0839fe005b 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 2.3E-10 T 06-07-2017 LK06_RS29800 0724a781155b1632eaa2eb0839fe005b 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 414 433 2.3E-10 T 06-07-2017 LK06_RS29800 0724a781155b1632eaa2eb0839fe005b 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 2.3E-10 T 06-07-2017 LK06_RS29800 0724a781155b1632eaa2eb0839fe005b 487 Pfam PF07690 Major Facilitator Superfamily 23 423 2.2E-49 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS29800 0724a781155b1632eaa2eb0839fe005b 487 ProSitePatterns PS00217 Sugar transport proteins signature 2. 113 138 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LK06_RS29800 0724a781155b1632eaa2eb0839fe005b 487 Gene3D G3DSA:1.20.1250.20 269 478 1.4E-18 T 06-07-2017 LK06_RS29800 0724a781155b1632eaa2eb0839fe005b 487 Gene3D G3DSA:1.20.1250.20 13 205 2.4E-28 T 06-07-2017 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 Gene3D G3DSA:3.40.1060.10 241 358 2.1E-36 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 Pfam PF00330 Aconitase family (aconitate hydratase) 64 574 2.5E-181 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 PRINTS PR00415 Aconitase family signature 270 283 4.4E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 PRINTS PR00415 Aconitase family signature 363 377 4.4E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 PRINTS PR00415 Aconitase family signature 284 297 4.4E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 PRINTS PR00415 Aconitase family signature 443 454 4.4E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 PRINTS PR00415 Aconitase family signature 194 207 4.4E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 PRINTS PR00415 Aconitase family signature 208 223 4.4E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 PRINTS PR00415 Aconitase family signature 505 518 4.4E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 PRINTS PR00415 Aconitase family signature 141 154 4.4E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 PRINTS PR00415 Aconitase family signature 165 173 4.4E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 26 903 0.0 T 06-07-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 SUPERFAMILY SSF52016 643 903 3.73E-85 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 ProSitePatterns PS01244 Aconitase family signature 2. 505 518 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 SUPERFAMILY SSF53732 4 639 1.02E-221 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 ProSitePatterns PS00450 Aconitase family signature 1. 439 455 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 Gene3D G3DSA:3.30.499.10 28 240 9.4E-78 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 Gene3D G3DSA:3.30.499.10 359 384 1.4E-63 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 Gene3D G3DSA:3.30.499.10 431 587 1.4E-63 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 Pfam PF00694 Aconitase C-terminal domain 704 833 2.8E-44 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS26520 dc8141fb598a5182dadfc01b7bb41c46 906 Gene3D G3DSA:3.20.19.10 649 903 2.0E-77 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 SUPERFAMILY SSF53927 218 520 2.41E-116 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 SUPERFAMILY SSF52335 10 199 2.22E-64 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 SMART SM00798 141 454 1.3E-186 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 PIRSF PIRSF000414 4 520 3.3E-195 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 Pfam PF01808 AICARFT/IMPCHase bienzyme 141 453 1.7E-113 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 Gene3D G3DSA:3.40.140.20 246 362 3.2E-46 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 Gene3D G3DSA:3.40.50.1380 9 191 1.3E-76 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 Pfam PF02142 MGS-like domain 22 135 1.9E-23 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 Gene3D G3DSA:3.40.140.20 367 510 1.3E-48 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 10 520 41.737 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 12 520 1.2E-169 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS20360 81a5452f4b1d749f6fd9a9a4f28da432 520 SMART SM00851 22 136 1.4E-49 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain LK06_RS02095 52f1f603ed21a8983fb1d69cbdc7c834 871 Pfam PF12770 CHAT domain 623 863 2.0E-28 T 06-07-2017 IPR024983 CHAT domain LK06_RS02095 52f1f603ed21a8983fb1d69cbdc7c834 871 Gene3D G3DSA:1.25.40.10 213 432 6.0E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS02095 52f1f603ed21a8983fb1d69cbdc7c834 871 SMART SM00028 200 233 440.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS02095 52f1f603ed21a8983fb1d69cbdc7c834 871 SMART SM00028 84 117 200.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS02095 52f1f603ed21a8983fb1d69cbdc7c834 871 SMART SM00028 120 153 1.1 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS02095 52f1f603ed21a8983fb1d69cbdc7c834 871 SMART SM00028 160 193 19.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS02095 52f1f603ed21a8983fb1d69cbdc7c834 871 Gene3D G3DSA:1.25.40.10 46 212 1.3E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS02095 52f1f603ed21a8983fb1d69cbdc7c834 871 SUPERFAMILY SSF48452 75 239 1.2E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS02810 edc9de7ef9c1af4201cc8407c275403f 690 Gene3D G3DSA:1.20.1560.10 88 379 1.3E-10 T 06-07-2017 LK06_RS02810 edc9de7ef9c1af4201cc8407c275403f 690 SUPERFAMILY SSF90123 80 378 1.83E-13 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS02810 edc9de7ef9c1af4201cc8407c275403f 690 Pfam PF00005 ABC transporter 431 590 1.2E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS02810 edc9de7ef9c1af4201cc8407c275403f 690 SMART SM00382 440 637 3.6E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS02810 edc9de7ef9c1af4201cc8407c275403f 690 Gene3D G3DSA:3.40.50.300 416 659 5.9E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02810 edc9de7ef9c1af4201cc8407c275403f 690 SUPERFAMILY SSF52540 408 662 1.89E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 35 708 5.3E-201 T 06-07-2017 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 SMART SM00487 278 480 6.8E-31 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 SMART SM00490 546 631 4.3E-23 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 Pfam PF01336 OB-fold nucleic acid binding domain 69 149 4.2E-9 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 Gene3D G3DSA:3.40.50.300 477 679 1.2E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 Gene3D G3DSA:2.40.50.140 55 156 4.8E-13 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 SUPERFAMILY SSF52540 412 641 1.0E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 SUPERFAMILY SSF52540 203 473 1.26E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 Pfam PF00270 DEAD/DEAH box helicase 306 456 6.6E-16 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 Pfam PF00271 Helicase conserved C-terminal domain 558 630 1.1E-19 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 SUPERFAMILY SSF50249 16 193 4.8E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS24265 068d3ae42391e8406b06dc8bd0cc1c9d 743 Gene3D G3DSA:3.40.50.300 267 476 8.7E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01365 9f5627097b5518902a997c66909738c4 139 Gene3D G3DSA:2.60.120.10 4 132 2.5E-29 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS01365 9f5627097b5518902a997c66909738c4 139 Pfam PF07883 Cupin domain 39 100 6.6E-10 T 06-07-2017 IPR013096 Cupin 2, conserved barrel LK06_RS01365 9f5627097b5518902a997c66909738c4 139 SUPERFAMILY SSF51182 9 132 1.09E-24 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS01245 89727dabc26e46425f2f49b0762a8fba 396 Pfam PF06081 Aromatic acid exporter family member 1 3 138 3.0E-9 T 06-07-2017 IPR010343 Aromatic acid exporter family member 1 LK06_RS24665 e1bbac88038f50217e6fc41b864a31a4 444 SUPERFAMILY SSF53383 36 442 6.4E-126 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS24665 e1bbac88038f50217e6fc41b864a31a4 444 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS24665 e1bbac88038f50217e6fc41b864a31a4 444 Pfam PF00202 Aminotransferase class-III 36 440 3.0E-120 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS24665 e1bbac88038f50217e6fc41b864a31a4 444 Gene3D G3DSA:3.40.640.10 75 323 2.9E-78 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS24665 e1bbac88038f50217e6fc41b864a31a4 444 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 25 441 2.8E-179 T 06-07-2017 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 LK06_RS24665 e1bbac88038f50217e6fc41b864a31a4 444 PIRSF PIRSF000521 1 444 1.7E-37 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS24665 e1bbac88038f50217e6fc41b864a31a4 444 Gene3D G3DSA:3.90.1150.10 324 443 2.6E-41 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS18875 eb59362e930d62b6192c91150f909230 131 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 19 54 5.6E-15 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal LK06_RS18875 eb59362e930d62b6192c91150f909230 131 SUPERFAMILY SSF50249 8 123 1.4E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS18875 eb59362e930d62b6192c91150f909230 131 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 56 121 7.6E-20 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal LK06_RS00895 e081687a6f064b7669dab83819fa16f1 264 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS00895 e081687a6f064b7669dab83819fa16f1 264 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS00895 e081687a6f064b7669dab83819fa16f1 264 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS00895 e081687a6f064b7669dab83819fa16f1 264 Gene3D G3DSA:1.10.357.10 59 192 7.5E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS00895 e081687a6f064b7669dab83819fa16f1 264 SUPERFAMILY SSF46689 11 86 4.73E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS00895 e081687a6f064b7669dab83819fa16f1 264 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 1.0E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS00895 e081687a6f064b7669dab83819fa16f1 264 Gene3D G3DSA:1.10.10.60 14 58 4.3E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS30855 59b1d2e42c1a5f7bd5b0bdc07faef803 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 228 240 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS30855 59b1d2e42c1a5f7bd5b0bdc07faef803 343 Gene3D G3DSA:1.10.600.10 15 342 1.1E-79 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS30855 59b1d2e42c1a5f7bd5b0bdc07faef803 343 SUPERFAMILY SSF48576 58 342 6.67E-74 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS30855 59b1d2e42c1a5f7bd5b0bdc07faef803 343 Pfam PF00348 Polyprenyl synthetase 61 289 1.7E-53 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 SUPERFAMILY SSF51230 1 76 1.02E-22 T 06-07-2017 IPR011053 Single hybrid motif LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 SUPERFAMILY SSF52777 268 485 1.33E-55 T 06-07-2017 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 SUPERFAMILY SSF47005 149 190 1.57E-11 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 269 485 1.1E-54 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 Gene3D G3DSA:4.10.320.10 196 239 7.2E-12 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 Gene3D G3DSA:4.10.320.10 153 193 4.5E-16 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 SUPERFAMILY SSF47005 194 236 5.49E-9 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 Pfam PF00364 Biotin-requiring enzyme 1 70 4.0E-18 T 06-07-2017 IPR000089 Biotin/lipoyl attachment LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 21 50 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 Pfam PF02817 e3 binding domain 198 233 1.1E-9 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 Pfam PF02817 e3 binding domain 155 188 3.9E-14 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 Gene3D G3DSA:2.40.50.100 1 75 4.4E-26 T 06-07-2017 LK06_RS00420 fe514b17cac669bd6c8f66b1faaf02df 486 Gene3D G3DSA:3.30.559.10 266 486 1.2E-52 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 LK06_RS21845 38aca593a18f13aa304ada122dfd2c3e 373 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 253 322 9.0E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21845 38aca593a18f13aa304ada122dfd2c3e 373 SMART SM00382 59 251 1.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS21845 38aca593a18f13aa304ada122dfd2c3e 373 ProSitePatterns PS00211 ABC transporters family signature. 174 188 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS21845 38aca593a18f13aa304ada122dfd2c3e 373 Gene3D G3DSA:3.40.50.300 21 275 7.3E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21845 38aca593a18f13aa304ada122dfd2c3e 373 SUPERFAMILY SSF52540 22 272 9.76E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21845 38aca593a18f13aa304ada122dfd2c3e 373 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 251 345 1.5E-25 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21845 38aca593a18f13aa304ada122dfd2c3e 373 Pfam PF00005 ABC transporter 51 201 7.2E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS22590 cad28800e6e40566c7c2c1555e0d15b4 69 SUPERFAMILY SSF88659 39 65 1.31E-5 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22590 cad28800e6e40566c7c2c1555e0d15b4 69 Pfam PF13384 Homeodomain-like domain 41 63 6.0E-6 T 06-07-2017 LK06_RS22590 cad28800e6e40566c7c2c1555e0d15b4 69 Gene3D G3DSA:1.10.10.60 37 64 1.6E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS27715 89cff6631ec29ab00be59eadb2faf83a 453 Gene3D G3DSA:3.30.830.10 12 215 4.3E-20 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 LK06_RS27715 89cff6631ec29ab00be59eadb2faf83a 453 SUPERFAMILY SSF63411 266 435 4.77E-16 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LK06_RS27715 89cff6631ec29ab00be59eadb2faf83a 453 Gene3D G3DSA:3.30.830.10 266 436 2.9E-13 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 LK06_RS27715 89cff6631ec29ab00be59eadb2faf83a 453 SUPERFAMILY SSF63411 7 228 2.5E-27 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LK06_RS27715 89cff6631ec29ab00be59eadb2faf83a 453 Pfam PF05193 Peptidase M16 inactive domain 173 365 3.7E-15 T 06-07-2017 IPR007863 Peptidase M16, C-terminal LK06_RS08030 19f303344f1a96071dffc65d67bff593 229 ProDom PD068376 ORF2 SECRETED GLNII PRECURSOR SIGNAL 1 229 3.0E-56 T 06-07-2017 LK06_RS08030 19f303344f1a96071dffc65d67bff593 229 Gene3D G3DSA:2.40.40.10 110 216 2.8E-4 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain LK06_RS02970 ef996b677bf3ed4d0d2c1d2d9fe37a0e 182 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 13 90 2.4E-9 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS02970 ef996b677bf3ed4d0d2c1d2d9fe37a0e 182 Gene3D G3DSA:3.40.50.1240 10 176 8.5E-53 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS02970 ef996b677bf3ed4d0d2c1d2d9fe37a0e 182 SUPERFAMILY SSF53254 11 174 7.5E-26 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS32065 1ee114134b5cfb0f2db8c5496d169f7c 226 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 217 38.491 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 LK06_RS32065 1ee114134b5cfb0f2db8c5496d169f7c 226 SUPERFAMILY SSF52402 1 219 1.72E-49 T 06-07-2017 LK06_RS32065 1ee114134b5cfb0f2db8c5496d169f7c 226 PIRSF PIRSF006293 1 223 9.7E-55 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 LK06_RS32065 1ee114134b5cfb0f2db8c5496d169f7c 226 Pfam PF06508 Queuosine biosynthesis protein QueC 4 210 4.1E-47 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 LK06_RS32065 1ee114134b5cfb0f2db8c5496d169f7c 226 Gene3D G3DSA:3.40.50.620 2 221 1.4E-55 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 SMART SM00636 243 596 1.2E-110 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 SUPERFAMILY SSF54556 508 567 5.27E-14 T 06-07-2017 IPR029070 Chitinase insertion domain LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 SMART SM00060 146 220 7.0E-10 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 Gene3D G3DSA:2.60.40.290 37 136 1.7E-35 T 06-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 ProSitePatterns PS01095 Chitinases family 18 active site. 377 385 - T 06-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 Gene3D G3DSA:3.20.20.80 233 509 5.6E-86 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 Gene3D G3DSA:3.20.20.80 573 609 5.6E-86 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 SUPERFAMILY SSF49265 144 225 5.84E-16 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 SMART SM00637 37 134 2.1E-43 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 Pfam PF00553 Cellulose binding domain 37 134 5.8E-32 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 SUPERFAMILY SSF49384 33 135 1.67E-31 T 06-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 Gene3D G3DSA:2.60.40.10 144 228 5.5E-22 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 Gene3D G3DSA:3.10.50.10 510 568 5.7E-24 T 06-07-2017 IPR029070 Chitinase insertion domain LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 Pfam PF00704 Glycosyl hydrolases family 18 246 596 1.2E-73 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 SUPERFAMILY SSF51445 237 506 4.68E-83 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS23320 fe4678902c5f133ec430f3157ae4e62f 610 SUPERFAMILY SSF51445 566 608 4.68E-83 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 Pfam PF00271 Helicase conserved C-terminal domain 229 343 2.9E-8 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 10 839 1.1E-218 T 06-07-2017 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 Gene3D G3DSA:3.40.50.300 221 358 3.6E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 Pfam PF04408 Helicase associated domain (HA2) 406 470 1.2E-6 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 SMART SM00490 247 345 9.0E-9 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 SMART SM00487 8 197 2.1E-18 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 SUPERFAMILY SSF52540 21 173 4.66E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 SUPERFAMILY SSF52540 200 355 4.66E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 Pfam PF08482 ATP-dependent helicase C-terminal 696 828 6.6E-49 T 06-07-2017 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 Gene3D G3DSA:3.40.50.300 10 172 3.1E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 SMART SM00847 405 493 6.8E-8 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 LK06_RS06860 ed69d4b0f1ae539ee2e407faceea8913 843 PIRSF PIRSF005496 5 842 4.2E-257 T 06-07-2017 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 Pfam PF03704 Bacterial transcriptional activator domain 132 276 4.6E-44 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 Pfam PF00931 NB-ARC domain 334 518 6.8E-15 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SUPERFAMILY SSF48452 129 298 1.59E-36 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SUPERFAMILY SSF48452 871 982 3.21E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SUPERFAMILY SSF52540 301 564 8.42E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 Gene3D G3DSA:1.25.40.10 758 982 1.7E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 Gene3D G3DSA:1.25.40.10 140 163 1.7E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SMART SM00028 951 984 31.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SMART SM00028 791 824 400.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SMART SM00028 137 170 380.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SMART SM00028 871 904 13.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SMART SM00028 751 784 190.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SMART SM00028 831 864 120.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 Gene3D G3DSA:3.40.50.300 315 432 1.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SUPERFAMILY SSF46894 40 112 2.04E-11 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SUPERFAMILY SSF48452 788 904 4.68E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 Gene3D G3DSA:1.10.10.10 49 112 6.2E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 PRINTS PR00364 Disease resistance protein signature 336 351 2.9E-9 T 06-07-2017 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 PRINTS PR00364 Disease resistance protein signature 498 512 2.9E-9 T 06-07-2017 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 PRINTS PR00364 Disease resistance protein signature 413 427 2.9E-9 T 06-07-2017 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SMART SM01043 132 276 1.3E-51 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 SMART SM00862 52 124 4.5E-9 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 Pfam PF00486 Transcriptional regulatory protein, C terminal 59 112 5.9E-8 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS18960 8bee73e054a2013a0c845a1aeea992d8 1002 Pfam PF13424 Tetratricopeptide repeat 794 858 1.4E-8 T 06-07-2017 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 SUPERFAMILY SSF51569 27 337 9.34E-94 T 06-07-2017 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 12 573 54.781 T 06-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 11 573 1.6E-251 T 06-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 SUPERFAMILY SSF89000 405 454 1.73E-15 T 06-07-2017 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 250 263 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 SMART SM00917 439 572 2.3E-41 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 SUPERFAMILY SSF110921 473 571 4.97E-36 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 Pfam PF00682 HMGL-like 37 318 3.6E-74 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 Gene3D G3DSA:3.20.20.70 16 410 4.3E-142 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 44 60 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS09370 dc38e883d0a992b62d1a9aea354f98c9 573 Pfam PF08502 LeuA allosteric (dimerisation) domain 439 571 1.6E-35 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LK06_RS29835 59f76a3a94625a6874d6f2bde48447f0 225 SMART SM00986 53 212 1.1E-27 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS29835 59f76a3a94625a6874d6f2bde48447f0 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 223 33.073 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS29835 59f76a3a94625a6874d6f2bde48447f0 225 Pfam PF03167 Uracil DNA glycosylase superfamily 55 210 5.6E-17 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS29835 59f76a3a94625a6874d6f2bde48447f0 225 SUPERFAMILY SSF52141 9 224 9.16E-69 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS29835 59f76a3a94625a6874d6f2bde48447f0 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 06-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS29835 59f76a3a94625a6874d6f2bde48447f0 225 SMART SM00987 53 212 1.1E-27 T 06-07-2017 LK06_RS29835 59f76a3a94625a6874d6f2bde48447f0 225 Gene3D G3DSA:3.40.470.10 7 224 4.1E-78 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS20185 cdfed8eca4bec162936711cdb39fa061 640 SUPERFAMILY SSF56112 1 277 1.28E-60 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS20185 cdfed8eca4bec162936711cdb39fa061 640 SMART SM00220 1 254 4.0E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20185 cdfed8eca4bec162936711cdb39fa061 640 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 2 25 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS20185 cdfed8eca4bec162936711cdb39fa061 640 Pfam PF00069 Protein kinase domain 2 242 1.2E-43 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20185 cdfed8eca4bec162936711cdb39fa061 640 Gene3D G3DSA:3.30.200.20 1 65 1.4E-16 T 06-07-2017 LK06_RS20185 cdfed8eca4bec162936711cdb39fa061 640 Gene3D G3DSA:1.10.510.10 66 250 2.4E-43 T 06-07-2017 LK06_RS20185 cdfed8eca4bec162936711cdb39fa061 640 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 119 131 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS30415 2bfc62e1c19820b74d396bb892c042a1 201 SUPERFAMILY SSF56524 17 200 2.62E-52 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS30415 2bfc62e1c19820b74d396bb892c042a1 201 Gene3D G3DSA:3.90.420.10 18 198 2.3E-43 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS30415 2bfc62e1c19820b74d396bb892c042a1 201 Pfam PF00174 Oxidoreductase molybdopterin binding domain 38 181 1.6E-27 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 SMART SM00382 234 374 2.6E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 Gene3D G3DSA:1.10.8.60 381 446 2.9E-26 T 06-07-2017 LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 147 634 1.5E-188 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 SUPERFAMILY SSF52540 197 443 3.58E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 Pfam PF01434 Peptidase family M41 433 633 4.4E-70 T 06-07-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 32 649 33.698 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 238 370 5.9E-41 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 Gene3D G3DSA:3.40.50.300 197 380 4.7E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 ProSitePatterns PS00674 AAA-protein family signature. 342 360 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 Pfam PF06480 FtsH Extracellular 38 138 1.8E-7 T 06-07-2017 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 LK06_RS24395 2b13a1394ea50bc8df054f1d6d7f9ce3 650 SUPERFAMILY SSF140990 452 635 1.44E-60 T 06-07-2017 LK06_RS06245 a3a5e319dbc4eed703c6fedeae99feed 668 Gene3D G3DSA:3.40.50.410 484 598 8.6E-15 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS06245 a3a5e319dbc4eed703c6fedeae99feed 668 Gene3D G3DSA:1.10.8.80 247 335 1.1E-34 T 06-07-2017 LK06_RS06245 a3a5e319dbc4eed703c6fedeae99feed 668 SUPERFAMILY SSF53300 484 647 1.67E-23 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS06245 a3a5e319dbc4eed703c6fedeae99feed 668 Pfam PF13519 von Willebrand factor type A domain 484 590 3.1E-17 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS06245 a3a5e319dbc4eed703c6fedeae99feed 668 Gene3D G3DSA:3.40.50.300 4 201 2.6E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06245 a3a5e319dbc4eed703c6fedeae99feed 668 SUPERFAMILY SSF52540 4 329 1.09E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06245 a3a5e319dbc4eed703c6fedeae99feed 668 SMART SM00382 28 205 4.4E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS06245 a3a5e319dbc4eed703c6fedeae99feed 668 SMART SM00327 481 658 2.2E-20 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS06245 a3a5e319dbc4eed703c6fedeae99feed 668 Pfam PF01078 Magnesium chelatase, subunit ChlI 113 182 9.0E-7 T 06-07-2017 IPR000523 Magnesium chelatase ChlI domain LK06_RS06245 a3a5e319dbc4eed703c6fedeae99feed 668 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 5 646 5.3E-256 T 06-07-2017 IPR012804 Cobaltochelatase subunit, putative LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 SUPERFAMILY SSF51971 334 519 5.89E-45 T 06-07-2017 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 377 634 2.7E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 498 516 1.4E-11 T 06-07-2017 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 617 633 1.4E-11 T 06-07-2017 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 378 397 1.4E-11 T 06-07-2017 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 Gene3D G3DSA:3.50.50.60 470 624 1.1E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 Gene3D G3DSA:3.50.50.60 361 465 1.2E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 330 3.3E-87 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 SUPERFAMILY SSF51905 461 519 5.18E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 SUPERFAMILY SSF51905 555 649 5.18E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 SUPERFAMILY SSF51395 2 367 5.07E-114 T 06-07-2017 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 Gene3D G3DSA:3.20.20.70 4 360 6.6E-124 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 618 632 6.2E-6 T 06-07-2017 LK06_RS30455 bb3a128cb30a0da33e571ff0e6039eee 671 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 399 6.2E-6 T 06-07-2017 LK06_RS00165 e13232e060cb9c5cd3c5385b72077808 183 Pfam PF12724 Flavodoxin domain 24 154 4.4E-24 T 06-07-2017 IPR026816 Flavodoxin domain LK06_RS00165 e13232e060cb9c5cd3c5385b72077808 183 Gene3D G3DSA:3.40.50.360 22 179 1.4E-15 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS00165 e13232e060cb9c5cd3c5385b72077808 183 SUPERFAMILY SSF52218 22 177 1.82E-13 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS31940 c8381b070700db834d1a5f4426fa41ca 652 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 260 612 1.5E-65 T 06-07-2017 IPR003776 YcaO-like domain LK06_RS31940 c8381b070700db834d1a5f4426fa41ca 652 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 75 231 2.8E-15 T 06-07-2017 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain LK06_RS27855 ad786b48ffdf8f06a5bd12de8e012b58 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 260 2.0E-62 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS27855 ad786b48ffdf8f06a5bd12de8e012b58 280 SUPERFAMILY SSF56317 3 277 4.71E-76 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS27855 ad786b48ffdf8f06a5bd12de8e012b58 280 Gene3D G3DSA:3.60.110.10 3 278 1.0E-84 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 SUPERFAMILY SSF51905 3 168 5.77E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 SUPERFAMILY SSF51905 265 355 5.77E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 Gene3D G3DSA:3.50.50.60 4 173 4.4E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 Gene3D G3DSA:3.50.50.60 266 347 4.4E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 Pfam PF01494 FAD binding domain 3 342 4.2E-42 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 1.4E-29 T 06-07-2017 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.4E-29 T 06-07-2017 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 1.4E-29 T 06-07-2017 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 329 1.4E-29 T 06-07-2017 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 345 1.4E-29 T 06-07-2017 LK06_RS25055 f228b6a524e74cfa22eb6d72cd806809 533 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.4E-29 T 06-07-2017 LK06_RS26780 4041f78fecfa1f28dcd474df5936d147 886 SUPERFAMILY SSF55874 509 647 5.24E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS26780 4041f78fecfa1f28dcd474df5936d147 886 Pfam PF00672 HAMP domain 339 421 8.9E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS26780 4041f78fecfa1f28dcd474df5936d147 886 SMART SM00387 538 648 0.0024 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS26780 4041f78fecfa1f28dcd474df5936d147 886 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 542 646 2.1E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS26780 4041f78fecfa1f28dcd474df5936d147 886 Gene3D G3DSA:3.30.565.10 542 646 1.2E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS26780 4041f78fecfa1f28dcd474df5936d147 886 SMART SM00304 356 426 1.3E-5 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 PRINTS PR01036 Tetracycline resistance protein TetB signature 51 75 2.1E-6 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 161 2.1E-6 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 PRINTS PR01036 Tetracycline resistance protein TetB signature 171 195 2.1E-6 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 PRINTS PR01036 Tetracycline resistance protein TetB signature 236 254 2.1E-6 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 SUPERFAMILY SSF49464 558 635 1.88E-8 T 06-07-2017 IPR008969 Carboxypeptidase-like, regulatory domain LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 48 461 3.3E-79 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 SUPERFAMILY SSF103473 282 454 6.37E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 SUPERFAMILY SSF103473 499 525 6.37E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 SUPERFAMILY SSF103473 34 229 6.37E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 Gene3D G3DSA:1.20.1250.20 52 230 1.3E-34 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 Gene3D G3DSA:1.20.1250.20 505 533 1.5E-17 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 Gene3D G3DSA:1.20.1250.20 297 460 1.5E-17 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 Pfam PF13620 Carboxypeptidase regulatory-like domain 560 635 1.3E-9 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 Pfam PF13620 Carboxypeptidase regulatory-like domain 641 719 2.5E-15 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 Pfam PF13620 Carboxypeptidase regulatory-like domain 725 801 3.8E-12 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 SUPERFAMILY SSF49478 725 792 1.02E-10 T 06-07-2017 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 Gene3D G3DSA:2.60.40.10 726 777 3.2E-10 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 Pfam PF07690 Major Facilitator Superfamily 52 445 1.1E-56 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 Gene3D G3DSA:2.60.40.1120 559 635 5.0E-7 T 06-07-2017 IPR014766 Carboxypeptidase, regulatory domain LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 Gene3D G3DSA:2.60.40.1120 641 721 6.3E-14 T 06-07-2017 IPR014766 Carboxypeptidase, regulatory domain LK06_RS28025 2924a6c0fcd533ce647b9fac734ac409 805 SUPERFAMILY SSF49452 635 719 8.44E-13 T 06-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 LK06_RS24255 ea37638eba9b06b47eafc267530615b3 981 Gene3D G3DSA:1.25.40.10 444 509 6.2E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS24255 ea37638eba9b06b47eafc267530615b3 981 Gene3D G3DSA:1.25.40.10 569 705 6.2E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS24255 ea37638eba9b06b47eafc267530615b3 981 SUPERFAMILY SSF48452 730 843 4.17E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS24255 ea37638eba9b06b47eafc267530615b3 981 SUPERFAMILY SSF48452 566 759 4.55E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS24255 ea37638eba9b06b47eafc267530615b3 981 Gene3D G3DSA:1.25.40.10 706 803 5.7E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22580 7b8943ae6796ea05f99fa0fcddf12f7d 407 Pfam PF00390 Malic enzyme, N-terminal domain 37 168 5.5E-28 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LK06_RS22580 7b8943ae6796ea05f99fa0fcddf12f7d 407 Gene3D G3DSA:3.40.50.10380 33 177 1.9E-54 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LK06_RS22580 7b8943ae6796ea05f99fa0fcddf12f7d 407 SUPERFAMILY SSF51735 180 406 3.68E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22580 7b8943ae6796ea05f99fa0fcddf12f7d 407 Gene3D G3DSA:3.40.50.720 178 406 1.4E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22580 7b8943ae6796ea05f99fa0fcddf12f7d 407 PIRSF PIRSF000106 38 407 1.0E-71 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 LK06_RS22580 7b8943ae6796ea05f99fa0fcddf12f7d 407 Pfam PF03949 Malic enzyme, NAD binding domain 182 381 1.6E-18 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 LK06_RS22580 7b8943ae6796ea05f99fa0fcddf12f7d 407 SMART SM00919 180 400 1.2E-105 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 LK06_RS22580 7b8943ae6796ea05f99fa0fcddf12f7d 407 SMART SM01274 35 168 3.8E-79 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LK06_RS22580 7b8943ae6796ea05f99fa0fcddf12f7d 407 SUPERFAMILY SSF53223 30 178 2.37E-56 T 06-07-2017 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 444 1.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 1.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 425 1.2E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 SUPERFAMILY SSF55874 288 446 8.91E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 SMART SM00387 341 447 5.7E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 Gene3D G3DSA:1.10.287.130 223 293 4.7E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 SUPERFAMILY SSF158472 180 228 4.97E-6 T 06-07-2017 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 SMART SM00304 179 232 6.9E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 Pfam PF00672 HAMP domain 160 228 1.6E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 445 7.6E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 SUPERFAMILY SSF47384 216 296 7.06E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 SMART SM00388 233 297 7.4E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 296 3.1E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS14355 01abb772726f7bb8c9a15704b21f50d5 458 Gene3D G3DSA:3.30.565.10 300 445 5.4E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17835 a240f12828fb948145d6e03292b7088d 229 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 4.8E-57 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 LK06_RS17835 a240f12828fb948145d6e03292b7088d 229 Pfam PF01895 PhoU domain 16 103 9.0E-18 T 06-07-2017 IPR026022 PhoU domain LK06_RS17835 a240f12828fb948145d6e03292b7088d 229 Pfam PF01895 PhoU domain 121 204 3.3E-12 T 06-07-2017 IPR026022 PhoU domain LK06_RS17835 a240f12828fb948145d6e03292b7088d 229 SUPERFAMILY SSF109755 2 216 1.05E-58 T 06-07-2017 LK06_RS17835 a240f12828fb948145d6e03292b7088d 229 PIRSF PIRSF003107 1 216 1.2E-54 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 LK06_RS17835 a240f12828fb948145d6e03292b7088d 229 Gene3D G3DSA:1.20.58.220 116 215 5.7E-22 T 06-07-2017 LK06_RS17835 a240f12828fb948145d6e03292b7088d 229 Gene3D G3DSA:1.20.58.220 1 105 2.5E-28 T 06-07-2017 LK06_RS11770 2bfcf06390b020d2317be448e9823c6e 225 Gene3D G3DSA:1.10.10.10 124 222 2.9E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11770 2bfcf06390b020d2317be448e9823c6e 225 SMART SM00448 3 113 5.2E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS11770 2bfcf06390b020d2317be448e9823c6e 225 SUPERFAMILY SSF52172 4 177 5.55E-43 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS11770 2bfcf06390b020d2317be448e9823c6e 225 SMART SM00862 146 222 3.3E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS11770 2bfcf06390b020d2317be448e9823c6e 225 Pfam PF00072 Response regulator receiver domain 5 114 4.0E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS11770 2bfcf06390b020d2317be448e9823c6e 225 Gene3D G3DSA:3.40.50.2300 2 123 2.7E-40 T 06-07-2017 LK06_RS11770 2bfcf06390b020d2317be448e9823c6e 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.8E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS18670 9b1d7f57d79486cf768c7be56887fed2 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS18670 9b1d7f57d79486cf768c7be56887fed2 544 Gene3D G3DSA:3.30.300.30 424 522 2.1E-30 T 06-07-2017 LK06_RS18670 9b1d7f57d79486cf768c7be56887fed2 544 Pfam PF00501 AMP-binding enzyme 24 427 1.0E-100 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS18670 9b1d7f57d79486cf768c7be56887fed2 544 Gene3D G3DSA:3.40.50.980 16 181 1.3E-33 T 06-07-2017 LK06_RS18670 9b1d7f57d79486cf768c7be56887fed2 544 SUPERFAMILY SSF56801 10 527 9.42E-150 T 06-07-2017 LK06_RS18670 9b1d7f57d79486cf768c7be56887fed2 544 Gene3D G3DSA:2.30.38.10 342 418 2.0E-28 T 06-07-2017 LK06_RS18670 9b1d7f57d79486cf768c7be56887fed2 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 512 9.9E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS18670 9b1d7f57d79486cf768c7be56887fed2 544 Gene3D G3DSA:3.40.50.980 182 339 7.4E-49 T 06-07-2017 LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 195 0.0018 T 06-07-2017 LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 5.5E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 5.5E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 5.5E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 SUPERFAMILY SSF51735 6 253 4.86E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 252 1.4E-52 T 06-07-2017 LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 Gene3D G3DSA:3.40.50.720 1 253 2.2E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS14870 2d41d79239fa17e9b6cbf78d5232a77e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.5E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 Pfam PF03471 Transporter associated domain 339 421 1.2E-12 T 06-07-2017 IPR005170 Transporter-associated domain LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 Pfam PF00571 CBS domain 200 256 6.8E-8 T 06-07-2017 IPR000644 CBS domain LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 Pfam PF00571 CBS domain 272 322 1.6E-7 T 06-07-2017 IPR000644 CBS domain LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 SUPERFAMILY SSF54631 195 337 4.04E-35 T 06-07-2017 LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 Pfam PF01595 Domain of unknown function DUF21 9 185 1.5E-30 T 06-07-2017 IPR002550 Domain of unknown function DUF21 LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 Gene3D G3DSA:3.10.580.10 186 329 4.0E-23 T 06-07-2017 LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 SMART SM00116 209 258 6.5E-4 T 06-07-2017 IPR000644 CBS domain LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 SMART SM00116 274 322 1.4 T 06-07-2017 IPR000644 CBS domain LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 SMART SM01091 337 423 1.5E-14 T 06-07-2017 IPR005170 Transporter-associated domain LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 Gene3D G3DSA:3.30.465.10 330 421 1.9E-19 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS09440 a1f2fe7e63fb69df15a305849d5d5ca0 428 SUPERFAMILY SSF56176 336 425 2.13E-11 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS20860 72dc98cd24e42d8fce38fc16e670d3ad 537 Gene3D G3DSA:3.90.226.10 284 537 7.3E-103 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS20860 72dc98cd24e42d8fce38fc16e670d3ad 537 Pfam PF01039 Carboxyl transferase domain 43 535 4.5E-197 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS20860 72dc98cd24e42d8fce38fc16e670d3ad 537 Gene3D G3DSA:3.90.226.10 16 269 1.0E-83 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS20860 72dc98cd24e42d8fce38fc16e670d3ad 537 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 144 162 4.5E-5 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 LK06_RS20860 72dc98cd24e42d8fce38fc16e670d3ad 537 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 110 124 4.5E-5 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 LK06_RS20860 72dc98cd24e42d8fce38fc16e670d3ad 537 SUPERFAMILY SSF52096 20 271 1.36E-80 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS20860 72dc98cd24e42d8fce38fc16e670d3ad 537 SUPERFAMILY SSF52096 258 537 2.49E-89 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 311 8.7E-119 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 Gene3D G3DSA:1.20.120.640 306 393 7.1E-19 T 06-07-2017 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 464 35.066 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 SUPERFAMILY SSF47323 330 463 2.22E-31 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 462 8.1E-137 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 SMART SM00840 341 403 2.6E-14 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 Gene3D G3DSA:3.40.50.620 21 303 4.1E-97 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.4E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.4E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 242 1.4E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 190 208 1.4E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 SUPERFAMILY SSF52374 4 310 7.51E-89 T 06-07-2017 LK06_RS17885 5f08048c59ae00f0dbbead7ff11f3c62 466 Pfam PF09190 DALR domain 341 394 5.2E-10 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 LK06_RS09620 f85fd2ebe1908c8c445a5bf0994371e2 223 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 31 221 30.736 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 LK06_RS09620 f85fd2ebe1908c8c445a5bf0994371e2 223 SUPERFAMILY SSF52374 30 221 1.13E-52 T 06-07-2017 LK06_RS09620 f85fd2ebe1908c8c445a5bf0994371e2 223 Pfam PF01467 Cytidylyltransferase-like 35 195 2.9E-30 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LK06_RS09620 f85fd2ebe1908c8c445a5bf0994371e2 223 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 34 97 1.3E-10 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LK06_RS09620 f85fd2ebe1908c8c445a5bf0994371e2 223 Gene3D G3DSA:3.40.50.620 31 222 1.5E-66 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS09620 f85fd2ebe1908c8c445a5bf0994371e2 223 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 35 220 4.5E-54 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 Pfam PF00072 Response regulator receiver domain 33 144 3.6E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 ProSitePatterns PS00622 LuxR-type HTH domain signature. 198 225 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 198 7.8E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 214 7.8E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 214 226 7.8E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 SUPERFAMILY SSF46894 167 244 3.74E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 SUPERFAMILY SSF52172 30 162 1.32E-35 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 Gene3D G3DSA:1.10.10.10 151 245 8.6E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 SMART SM00448 31 144 2.1E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 SMART SM00421 181 238 3.2E-28 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 Pfam PF00196 Bacterial regulatory proteins, luxR family 183 238 4.5E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS11745 b0477e70bfa3a9ced7d9184e485274ec 247 Gene3D G3DSA:3.40.50.2300 27 150 1.7E-37 T 06-07-2017 LK06_RS12485 a6f117938b36abc48704067c5058af58 239 Gene3D G3DSA:3.40.30.10 63 219 1.4E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS12485 a6f117938b36abc48704067c5058af58 239 Pfam PF13462 Thioredoxin 57 217 3.9E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS12485 a6f117938b36abc48704067c5058af58 239 SUPERFAMILY SSF52833 51 226 5.97E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 PIRSF PIRSF016578 5 390 5.7E-19 T 06-07-2017 LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 385 6.3E-51 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 SUPERFAMILY SSF47203 235 387 4.34E-60 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 SUPERFAMILY SSF56645 13 250 3.53E-70 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 Gene3D G3DSA:1.20.140.10 225 388 4.1E-72 T 06-07-2017 LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 Gene3D G3DSA:1.10.540.10 14 125 1.1E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 225 1.1E-28 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 Gene3D G3DSA:2.40.110.10 129 224 1.2E-38 T 06-07-2017 LK06_RS03880 a7592f68b58bc3a6792049280df3856f 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 125 6.5E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS26080 cff7caebb10aab0d5a4c7dd6e227aceb 275 Gene3D G3DSA:1.10.12.10 217 275 2.4E-23 T 06-07-2017 IPR014748 Crontonase, C-terminal LK06_RS26080 cff7caebb10aab0d5a4c7dd6e227aceb 275 Gene3D G3DSA:3.90.226.10 15 216 2.3E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS26080 cff7caebb10aab0d5a4c7dd6e227aceb 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 274 6.5E-51 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS26080 cff7caebb10aab0d5a4c7dd6e227aceb 275 SUPERFAMILY SSF52096 11 275 3.85E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS26080 cff7caebb10aab0d5a4c7dd6e227aceb 275 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 115 135 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 LK06_RS23515 7d6c4ae2b24d88db3bedbc87e052dd43 323 Gene3D G3DSA:1.25.40.10 186 231 4.1E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS23515 7d6c4ae2b24d88db3bedbc87e052dd43 323 SUPERFAMILY SSF52833 49 155 4.69E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS23515 7d6c4ae2b24d88db3bedbc87e052dd43 323 Pfam PF14559 Tetratricopeptide repeat 197 232 1.1E-6 T 06-07-2017 LK06_RS23515 7d6c4ae2b24d88db3bedbc87e052dd43 323 Pfam PF14561 Tetratricopeptide repeat 235 323 1.4E-24 T 06-07-2017 LK06_RS23515 7d6c4ae2b24d88db3bedbc87e052dd43 323 Gene3D G3DSA:3.40.30.10 47 154 3.7E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS23515 7d6c4ae2b24d88db3bedbc87e052dd43 323 SUPERFAMILY SSF48452 186 322 7.36E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS23515 7d6c4ae2b24d88db3bedbc87e052dd43 323 Gene3D G3DSA:1.25.40.10 240 323 1.6E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS23515 7d6c4ae2b24d88db3bedbc87e052dd43 323 Pfam PF00085 Thioredoxin 51 152 4.5E-23 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 LK06_RS28890 12140c0c17293930b8f20a030b572b89 388 Pfam PF04443 Acyl-protein synthetase, LuxE 78 381 9.1E-27 T 06-07-2017 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 LK06_RS28890 12140c0c17293930b8f20a030b572b89 388 SUPERFAMILY SSF56801 79 332 3.51E-5 T 06-07-2017 LK06_RS19990 e971860ce196b1a0b395a72801cc632e 842 Pfam PF02687 FtsX-like permease family 269 390 2.3E-24 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS19990 e971860ce196b1a0b395a72801cc632e 842 Pfam PF02687 FtsX-like permease family 718 834 1.4E-20 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS19990 e971860ce196b1a0b395a72801cc632e 842 Pfam PF12704 MacB-like periplasmic core domain 490 684 3.9E-13 T 06-07-2017 IPR025857 MacB-like periplasmic core domain LK06_RS19990 e971860ce196b1a0b395a72801cc632e 842 Pfam PF12704 MacB-like periplasmic core domain 17 233 8.2E-20 T 06-07-2017 IPR025857 MacB-like periplasmic core domain LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 Pfam PF13419 Haloacid dehalogenase-like hydrolase 37 213 1.8E-15 T 06-07-2017 IPR023214 HAD-like domain LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 116 208 5.8E-8 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 SUPERFAMILY SSF56784 34 245 6.94E-36 T 06-07-2017 IPR023214 HAD-like domain LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 SMART SM00331 483 705 8.5E-31 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 510 705 1.1E-43 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 SUPERFAMILY SSF81606 498 660 2.17E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 Pfam PF13581 Histidine kinase-like ATPase domain 719 826 2.0E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 Gene3D G3DSA:3.30.450.40 280 460 1.5E-26 T 06-07-2017 IPR029016 GAF domain-like LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 SMART SM00065 282 462 0.0055 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 SUPERFAMILY SSF55781 370 456 9.38E-14 T 06-07-2017 IPR029016 GAF domain-like LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 Pfam PF01590 GAF domain 389 452 4.4E-7 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS31595 e6db5888a82ead78ee49cab5d674c97e 831 Gene3D G3DSA:3.40.50.1000 34 241 3.5E-33 T 06-07-2017 IPR023214 HAD-like domain LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 10 335 80.05 T 06-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 11 334 1.6E-119 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 151 2.4E-45 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 PRINTS PR00102 Ornithine carbamoyltransferase signature 87 100 3.2E-31 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 PRINTS PR00102 Ornithine carbamoyltransferase signature 54 68 3.2E-31 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 PRINTS PR00102 Ornithine carbamoyltransferase signature 232 242 3.2E-31 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 PRINTS PR00102 Ornithine carbamoyltransferase signature 127 141 3.2E-31 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 PRINTS PR00102 Ornithine carbamoyltransferase signature 313 324 3.2E-31 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 SUPERFAMILY SSF53671 8 334 2.1E-91 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 160 332 2.3E-47 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 Gene3D G3DSA:3.40.50.1370 148 321 6.1E-65 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 Gene3D G3DSA:3.40.50.1370 8 147 7.3E-55 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 299 322 1.7E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 1.7E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 1.7E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS26065 d01b1e00e6ea8f506202aef4f701ec72 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 279 1.7E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS08210 60bc55c7e0d7c4ee53e6bd6fcb4311cd 349 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 134 336 4.1E-19 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS08210 60bc55c7e0d7c4ee53e6bd6fcb4311cd 349 Gene3D G3DSA:3.60.10.10 131 280 4.6E-8 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS08210 60bc55c7e0d7c4ee53e6bd6fcb4311cd 349 SUPERFAMILY SSF56219 127 347 5.89E-27 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 SUPERFAMILY SSF82866 291 490 2.49E-42 T 06-07-2017 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 Gene3D G3DSA:1.10.3850.10 272 490 2.1E-57 T 06-07-2017 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 Gene3D G3DSA:1.10.3850.10 792 1005 3.7E-59 T 06-07-2017 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 Pfam PF00873 AcrB/AcrD/AcrF family 5 1005 8.9E-221 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 SUPERFAMILY SSF82866 783 1005 2.22E-50 T 06-07-2017 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 SUPERFAMILY SSF82693 267 322 3.82E-14 T 06-07-2017 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 SUPERFAMILY SSF82693 134 180 3.82E-14 T 06-07-2017 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 SUPERFAMILY SSF82693 41 130 1.54E-23 T 06-07-2017 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 SUPERFAMILY SSF82714 182 263 1.02E-11 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 1.6E-40 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 1.6E-40 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 1.6E-40 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.6E-40 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 1.6E-40 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 1.6E-40 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.6E-40 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 Gene3D G3DSA:3.30.2090.10 182 267 1.6E-11 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 Gene3D G3DSA:3.30.70.1430 41 138 1.9E-26 T 06-07-2017 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 SUPERFAMILY SSF82693 561 651 5.23E-7 T 06-07-2017 LK06_RS07700 a075db805b4cfb13b25c2050d8137521 1038 Gene3D G3DSA:3.30.70.1430 563 640 2.5E-6 T 06-07-2017 LK06_RS20865 d45cb8ba0f3f86993a5934b8b0fdaa82 288 Pfam PF02237 Biotin protein ligase C terminal domain 237 284 9.7E-9 T 06-07-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS20865 d45cb8ba0f3f86993a5934b8b0fdaa82 288 SUPERFAMILY SSF50037 245 284 7.78E-5 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal LK06_RS20865 d45cb8ba0f3f86993a5934b8b0fdaa82 288 Gene3D G3DSA:3.30.930.10 34 222 3.1E-51 T 06-07-2017 LK06_RS20865 d45cb8ba0f3f86993a5934b8b0fdaa82 288 Pfam PF03099 Biotin/lipoate A/B protein ligase family 63 171 5.5E-8 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 LK06_RS20865 d45cb8ba0f3f86993a5934b8b0fdaa82 288 SUPERFAMILY SSF55681 33 222 4.8E-42 T 06-07-2017 LK06_RS20865 d45cb8ba0f3f86993a5934b8b0fdaa82 288 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 42 284 6.9E-38 T 06-07-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS20865 d45cb8ba0f3f86993a5934b8b0fdaa82 288 Gene3D G3DSA:2.30.30.100 247 282 4.3E-4 T 06-07-2017 LK06_RS03795 8a7c60f5be3bcfa5eb5e0ec77afe5bbc 391 Pfam PF00534 Glycosyl transferases group 1 203 353 9.1E-23 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS03795 8a7c60f5be3bcfa5eb5e0ec77afe5bbc 391 Pfam PF13439 Glycosyltransferase Family 4 20 184 4.8E-16 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS03795 8a7c60f5be3bcfa5eb5e0ec77afe5bbc 391 SUPERFAMILY SSF53756 12 370 7.33E-56 T 06-07-2017 LK06_RS03795 8a7c60f5be3bcfa5eb5e0ec77afe5bbc 391 Gene3D G3DSA:3.40.50.2000 175 352 2.1E-23 T 06-07-2017 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 Pfam PF00108 Thiolase, N-terminal domain 1 258 1.7E-95 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 SUPERFAMILY SSF53901 1 266 2.62E-85 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 SUPERFAMILY SSF53901 268 387 6.58E-35 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 Pfam PF02803 Thiolase, C-terminal domain 267 387 1.2E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 ProSitePatterns PS00099 Thiolases active site. 370 383 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 2 386 9.9E-138 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 PIRSF PIRSF000429 1 390 5.3E-120 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 80 98 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 Gene3D G3DSA:3.40.47.10 190 272 1.8E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 Gene3D G3DSA:3.40.47.10 1 119 1.8E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 Gene3D G3DSA:3.40.47.10 138 189 2.0E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS23435 3cd0e7a9fcfd0540a6d32a38c8b57221 391 Gene3D G3DSA:3.40.47.10 273 388 2.0E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS14865 b093b993401573a136535c681c0f7e73 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.3E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS14865 b093b993401573a136535c681c0f7e73 201 SUPERFAMILY SSF48498 83 198 7.79E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS14865 b093b993401573a136535c681c0f7e73 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 8.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS14865 b093b993401573a136535c681c0f7e73 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 8.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS14865 b093b993401573a136535c681c0f7e73 201 Gene3D G3DSA:1.10.10.60 4 68 2.6E-26 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS14865 b093b993401573a136535c681c0f7e73 201 Gene3D G3DSA:1.10.357.10 73 199 5.4E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS14865 b093b993401573a136535c681c0f7e73 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS14865 b093b993401573a136535c681c0f7e73 201 SUPERFAMILY SSF46689 3 86 2.98E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02620 7b4f9c71afed40ae67c2e49dbee723aa 154 SUPERFAMILY SSF54427 15 138 6.23E-32 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS02620 7b4f9c71afed40ae67c2e49dbee723aa 154 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 17 141 3.9E-36 T 06-07-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 LK06_RS02620 7b4f9c71afed40ae67c2e49dbee723aa 154 Gene3D G3DSA:3.10.450.50 8 140 8.7E-39 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS02620 7b4f9c71afed40ae67c2e49dbee723aa 154 Pfam PF13474 SnoaL-like domain 22 139 1.4E-10 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain LK06_RS10055 28ed8b5aa98ab79b94d3fb30f8f0dc1c 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 5.1E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS10055 28ed8b5aa98ab79b94d3fb30f8f0dc1c 196 SUPERFAMILY SSF46689 7 69 5.13E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS10055 28ed8b5aa98ab79b94d3fb30f8f0dc1c 196 Gene3D G3DSA:1.10.357.10 68 190 8.7E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS10055 28ed8b5aa98ab79b94d3fb30f8f0dc1c 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 7.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS10055 28ed8b5aa98ab79b94d3fb30f8f0dc1c 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 7.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS10055 28ed8b5aa98ab79b94d3fb30f8f0dc1c 196 SUPERFAMILY SSF48498 82 189 3.51E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS10055 28ed8b5aa98ab79b94d3fb30f8f0dc1c 196 Gene3D G3DSA:1.10.10.60 9 67 1.1E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS07195 7ddc5e7bfa6ca1c8cd1f78118e6fac54 1179 Pfam PF14579 Helix-hairpin-helix motif 829 917 7.9E-24 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS07195 7ddc5e7bfa6ca1c8cd1f78118e6fac54 1179 Gene3D G3DSA:2.40.50.140 1015 1096 1.7E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS07195 7ddc5e7bfa6ca1c8cd1f78118e6fac54 1179 SUPERFAMILY SSF89550 7 269 1.01E-29 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 LK06_RS07195 7ddc5e7bfa6ca1c8cd1f78118e6fac54 1179 Pfam PF02811 PHP domain 8 194 2.2E-42 T 06-07-2017 IPR004013 PHP domain GO:0003824 LK06_RS07195 7ddc5e7bfa6ca1c8cd1f78118e6fac54 1179 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1057 0.0 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS07195 7ddc5e7bfa6ca1c8cd1f78118e6fac54 1179 Pfam PF01336 OB-fold nucleic acid binding domain 1020 1096 1.8E-6 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 LK06_RS07195 7ddc5e7bfa6ca1c8cd1f78118e6fac54 1179 Gene3D G3DSA:3.20.20.140 7 268 2.7E-38 T 06-07-2017 LK06_RS07195 7ddc5e7bfa6ca1c8cd1f78118e6fac54 1179 SMART SM00481 7 74 3.2E-28 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 LK06_RS07195 7ddc5e7bfa6ca1c8cd1f78118e6fac54 1179 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 316 755 1.5E-163 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS16090 eac1ec01ff7552a4453f1334b95afb20 237 Gene3D G3DSA:1.10.10.10 1 61 6.6E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16090 eac1ec01ff7552a4453f1334b95afb20 237 SUPERFAMILY SSF46785 1 60 7.14E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16090 eac1ec01ff7552a4453f1334b95afb20 237 Pfam PF09339 IclR helix-turn-helix domain 1 46 1.5E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS16090 eac1ec01ff7552a4453f1334b95afb20 237 SUPERFAMILY SSF55781 65 226 2.29E-22 T 06-07-2017 IPR029016 GAF domain-like LK06_RS16090 eac1ec01ff7552a4453f1334b95afb20 237 Pfam PF01614 Bacterial transcriptional regulator 122 209 2.7E-16 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal LK06_RS16090 eac1ec01ff7552a4453f1334b95afb20 237 Gene3D G3DSA:3.30.450.40 69 228 2.3E-25 T 06-07-2017 IPR029016 GAF domain-like LK06_RS26130 fb7973cefa3d9a8920044403c9e13e7d 276 SUPERFAMILY SSF161098 2 276 4.58E-71 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26130 fb7973cefa3d9a8920044403c9e13e7d 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 263 1.5E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26130 fb7973cefa3d9a8920044403c9e13e7d 276 Gene3D G3DSA:1.10.3720.10 5 263 6.0E-65 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS16680 6038981b2875a60118a914fed2adb08b 97 SUPERFAMILY SSF54909 1 94 2.15E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS16680 6038981b2875a60118a914fed2adb08b 97 SMART SM00886 2 97 1.6E-21 T 06-07-2017 IPR013097 Stress responsive alpha-beta barrel LK06_RS16680 6038981b2875a60118a914fed2adb08b 97 Gene3D G3DSA:3.30.70.900 1 96 7.6E-24 T 06-07-2017 LK06_RS16680 6038981b2875a60118a914fed2adb08b 97 Pfam PF07876 Stress responsive A/B Barrel Domain 2 96 2.1E-21 T 06-07-2017 IPR013097 Stress responsive alpha-beta barrel LK06_RS20390 111dc3afbdd6f9724a08a054b0fe6244 422 SMART SM00530 21 76 2.8E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS20390 111dc3afbdd6f9724a08a054b0fe6244 422 Pfam PF10901 Protein of unknown function (DUF2690) 320 410 1.2E-24 T 06-07-2017 IPR021224 Protein of unknown function DUF2690 LK06_RS20390 111dc3afbdd6f9724a08a054b0fe6244 422 SUPERFAMILY SSF47413 17 79 6.57E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS20390 111dc3afbdd6f9724a08a054b0fe6244 422 Pfam PF13560 Helix-turn-helix domain 18 74 5.4E-9 T 06-07-2017 LK06_RS20390 111dc3afbdd6f9724a08a054b0fe6244 422 Gene3D G3DSA:1.10.260.40 18 77 7.6E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS03785 62545c6958fed3a2a91afe4b07c8dacd 258 Pfam PF02626 Allophanate hydrolase subunit 2 57 252 5.3E-57 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B LK06_RS03785 62545c6958fed3a2a91afe4b07c8dacd 258 Gene3D G3DSA:2.40.100.10 145 257 4.0E-10 T 06-07-2017 IPR029000 Cyclophilin-like domain LK06_RS03785 62545c6958fed3a2a91afe4b07c8dacd 258 SMART SM00797 11 258 2.8E-38 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B LK06_RS03785 62545c6958fed3a2a91afe4b07c8dacd 258 SUPERFAMILY SSF50891 145 257 3.19E-14 T 06-07-2017 IPR029000 Cyclophilin-like domain LK06_RS14735 b07fe559247be3d74fc92f3506b8393e 372 Pfam PF13407 Periplasmic binding protein domain 47 307 2.9E-61 T 06-07-2017 IPR025997 Periplasmic binding protein LK06_RS14735 b07fe559247be3d74fc92f3506b8393e 372 Gene3D G3DSA:3.40.50.2300 45 158 9.7E-24 T 06-07-2017 LK06_RS14735 b07fe559247be3d74fc92f3506b8393e 372 SUPERFAMILY SSF53822 44 343 3.3E-57 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS14735 b07fe559247be3d74fc92f3506b8393e 372 Gene3D G3DSA:3.40.50.2300 159 343 7.7E-38 T 06-07-2017 LK06_RS11925 a13cff75bad90114cf65ff1864a4478d 360 Gene3D G3DSA:2.160.10.10 255 354 2.8E-14 T 06-07-2017 LK06_RS11925 a13cff75bad90114cf65ff1864a4478d 360 Gene3D G3DSA:3.90.550.10 2 238 2.7E-64 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11925 a13cff75bad90114cf65ff1864a4478d 360 Pfam PF00483 Nucleotidyl transferase 4 236 6.4E-45 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LK06_RS11925 a13cff75bad90114cf65ff1864a4478d 360 SUPERFAMILY SSF51161 255 354 7.2E-17 T 06-07-2017 IPR011004 Trimeric LpxA-like LK06_RS11925 a13cff75bad90114cf65ff1864a4478d 360 SUPERFAMILY SSF53448 3 241 4.96E-67 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11925 a13cff75bad90114cf65ff1864a4478d 360 SUPERFAMILY SSF53448 285 302 4.96E-67 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS23960 92e669b1100837da0582494862a7c4f2 174 Gene3D G3DSA:3.30.70.1150 84 163 2.3E-31 T 06-07-2017 LK06_RS23960 92e669b1100837da0582494862a7c4f2 174 Pfam PF10369 Small subunit of acetolactate synthase 85 158 4.5E-29 T 06-07-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 LK06_RS23960 92e669b1100837da0582494862a7c4f2 174 Gene3D G3DSA:3.30.70.260 1 78 4.5E-34 T 06-07-2017 LK06_RS23960 92e669b1100837da0582494862a7c4f2 174 SUPERFAMILY SSF55021 81 161 2.36E-26 T 06-07-2017 LK06_RS23960 92e669b1100837da0582494862a7c4f2 174 Pfam PF13710 ACT domain 13 74 4.4E-16 T 06-07-2017 LK06_RS23960 92e669b1100837da0582494862a7c4f2 174 SUPERFAMILY SSF55021 3 75 2.92E-22 T 06-07-2017 LK06_RS23960 92e669b1100837da0582494862a7c4f2 174 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 1.4E-61 T 06-07-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 LK06_RS23960 92e669b1100837da0582494862a7c4f2 174 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 7.0E-35 T 06-07-2017 LK06_RS31380 27c9e2c745b4c8eb47ed0d42b56c3092 430 SUPERFAMILY SSF81340 8 414 1.44E-34 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 LK06_RS31380 27c9e2c745b4c8eb47ed0d42b56c3092 430 Gene3D G3DSA:1.10.3080.10 7 416 8.2E-19 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 LK06_RS24715 87a171c594ee2202b18c96a4f9f9500d 282 Pfam PF13312 Domain of unknown function (DUF4081) 48 152 8.2E-44 T 06-07-2017 IPR025289 Domain of unknown function DUF4081 LK06_RS24715 87a171c594ee2202b18c96a4f9f9500d 282 Gene3D G3DSA:3.40.630.30 134 278 1.9E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS24715 87a171c594ee2202b18c96a4f9f9500d 282 Pfam PF00583 Acetyltransferase (GNAT) family 209 272 5.8E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS24715 87a171c594ee2202b18c96a4f9f9500d 282 SUPERFAMILY SSF55729 8 277 2.48E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS24715 87a171c594ee2202b18c96a4f9f9500d 282 PIRSF PIRSF021603 1 282 1.9E-142 T 06-07-2017 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 290 1.1E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 Gene3D G3DSA:3.50.50.60 165 310 1.9E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.7E-7 T 06-07-2017 LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 7.7E-7 T 06-07-2017 LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 7.7E-7 T 06-07-2017 LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 Gene3D G3DSA:3.50.50.60 2 164 2.5E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 1.5E-13 T 06-07-2017 LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.5E-13 T 06-07-2017 LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.5E-13 T 06-07-2017 LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.5E-13 T 06-07-2017 LK06_RS14940 443e84090fa0d98d3c9ba01d38d3845c 402 SUPERFAMILY SSF51905 1 329 5.51E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS28300 a3d1f682ddc15658bf6971fc44b29317 330 SUPERFAMILY SSF50129 6 155 4.87E-14 T 06-07-2017 IPR011032 GroES-like LK06_RS28300 a3d1f682ddc15658bf6971fc44b29317 330 Gene3D G3DSA:3.40.50.720 153 256 2.3E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28300 a3d1f682ddc15658bf6971fc44b29317 330 SUPERFAMILY SSF51735 121 263 2.7E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28300 a3d1f682ddc15658bf6971fc44b29317 330 Gene3D G3DSA:3.90.180.10 104 152 6.1E-5 T 06-07-2017 IPR011032 GroES-like LK06_RS28300 a3d1f682ddc15658bf6971fc44b29317 330 Gene3D G3DSA:3.90.180.10 5 86 3.2E-5 T 06-07-2017 IPR011032 GroES-like LK06_RS05620 72b7fa5dcfc49afc6427fdaaededbed0 234 Pfam PF01476 LysM domain 189 234 3.1E-12 T 06-07-2017 IPR018392 LysM domain LK06_RS05620 72b7fa5dcfc49afc6427fdaaededbed0 234 SUPERFAMILY SSF53955 47 127 9.09E-33 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS05620 72b7fa5dcfc49afc6427fdaaededbed0 234 Pfam PF06737 Transglycosylase-like domain 46 122 1.2E-34 T 06-07-2017 IPR010618 Transglycosylase-like LK06_RS05620 72b7fa5dcfc49afc6427fdaaededbed0 234 Gene3D G3DSA:1.10.530.10 32 127 7.1E-42 T 06-07-2017 LK06_RS05620 72b7fa5dcfc49afc6427fdaaededbed0 234 SUPERFAMILY SSF54106 187 234 1.83E-10 T 06-07-2017 IPR018392 LysM domain LK06_RS05620 72b7fa5dcfc49afc6427fdaaededbed0 234 SMART SM00257 188 234 1.1E-7 T 06-07-2017 IPR018392 LysM domain LK06_RS05620 72b7fa5dcfc49afc6427fdaaededbed0 234 Gene3D G3DSA:3.10.350.10 188 234 3.1E-15 T 06-07-2017 IPR018392 LysM domain LK06_RS01995 a579f1c1c4bcba077e67caa1d82f8d87 459 Pfam PF07690 Major Facilitator Superfamily 41 397 3.2E-39 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS01995 a579f1c1c4bcba077e67caa1d82f8d87 459 SUPERFAMILY SSF103473 26 441 2.75E-56 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS01995 a579f1c1c4bcba077e67caa1d82f8d87 459 Gene3D G3DSA:1.20.1250.20 235 440 5.0E-18 T 06-07-2017 LK06_RS01995 a579f1c1c4bcba077e67caa1d82f8d87 459 Gene3D G3DSA:1.20.1250.20 34 225 9.7E-26 T 06-07-2017 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 723 829 5.2E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 SUPERFAMILY SSF47384 604 682 1.39E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 Gene3D G3DSA:3.40.50.620 228 347 1.9E-9 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 210 9.2E-98 T 06-07-2017 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 SMART SM00388 614 682 4.2E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 SMART SM00387 722 832 1.1E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 816 829 1.8E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 792 810 1.8E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 759 773 1.8E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 777 787 1.8E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 Pfam PF13493 Domain of unknown function (DUF4118) 385 487 5.6E-22 T 06-07-2017 IPR025201 Sensor protein KdpD, transmembrane domain LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 Pfam PF00512 His Kinase A (phospho-acceptor) domain 615 682 5.7E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 Gene3D G3DSA:1.20.120.620 384 479 1.6E-14 T 06-07-2017 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 Gene3D G3DSA:3.40.50.300 2 210 1.5E-97 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 Gene3D G3DSA:3.30.565.10 669 831 2.1E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 Pfam PF00582 Universal stress protein family 232 347 3.0E-5 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 SUPERFAMILY SSF55874 672 828 6.16E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 Gene3D G3DSA:1.10.287.130 606 668 2.5E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25490 52fbf25b6b2a93f911b3f578a9696c01 860 SUPERFAMILY SSF52402 232 348 5.98E-9 T 06-07-2017 LK06_RS02570 6cde6e6659e47f6de8879056462e01a2 433 SUPERFAMILY SSF53098 10 159 6.98E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS02570 6cde6e6659e47f6de8879056462e01a2 433 Pfam PF13546 DDE superfamily endonuclease 19 201 1.0E-44 T 06-07-2017 LK06_RS09960 b0b80a78f22e9a9f91124f799b2339a7 413 Pfam PF13530 Sterol carrier protein domain 184 410 1.7E-49 T 06-07-2017 IPR025559 Enhanced intracellular survival protein domain LK06_RS09960 b0b80a78f22e9a9f91124f799b2339a7 413 SUPERFAMILY SSF55718 308 413 4.71E-25 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS09960 b0b80a78f22e9a9f91124f799b2339a7 413 Pfam PF13527 Acetyltransferase (GNAT) domain 11 134 1.3E-33 T 06-07-2017 LK06_RS09960 b0b80a78f22e9a9f91124f799b2339a7 413 Gene3D G3DSA:3.40.630.30 11 135 3.9E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS09960 b0b80a78f22e9a9f91124f799b2339a7 413 Gene3D G3DSA:3.30.1050.10 294 400 8.8E-25 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS09960 b0b80a78f22e9a9f91124f799b2339a7 413 Gene3D G3DSA:3.40.630.30 156 293 5.7E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS09960 b0b80a78f22e9a9f91124f799b2339a7 413 SUPERFAMILY SSF55729 12 307 7.43E-60 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 SUPERFAMILY SSF52540 435 574 4.12E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 SUPERFAMILY SSF52540 10 205 4.12E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 SUPERFAMILY SSF52540 619 914 4.11E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 ProSitePatterns PS00211 ABC transporters family signature. 834 848 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:1.20.1580.10 92 130 6.8E-56 T 06-07-2017 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:1.20.1580.10 255 288 6.8E-56 T 06-07-2017 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:1.20.1580.10 412 482 6.8E-56 T 06-07-2017 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:1.10.8.280 290 411 2.5E-36 T 06-07-2017 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 929 0.0 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:3.40.50.300 825 942 1.3E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:3.40.50.300 6 90 5.1E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:3.40.50.300 483 600 5.1E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:3.40.50.300 617 684 1.3E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:3.30.1490.20 201 242 6.3E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:3.30.1490.20 131 154 6.3E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Pfam PF00005 ABC transporter 628 864 8.6E-11 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Gene3D G3DSA:1.20.1580.10 698 824 2.8E-56 T 06-07-2017 LK06_RS06665 0e074bab4f62904f8bf7d0761c69cafe 1013 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 944 22.863 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 LK06_RS15900 9c14984908ac461055232aa235c29471 365 SMART SM00470 85 175 4.9E-32 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS15900 9c14984908ac461055232aa235c29471 365 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 82 260 3.6E-60 T 06-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 LK06_RS15900 9c14984908ac461055232aa235c29471 365 SUPERFAMILY SSF110849 69 178 1.33E-28 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS15900 9c14984908ac461055232aa235c29471 365 Gene3D G3DSA:3.90.1530.10 80 181 5.3E-39 T 06-07-2017 LK06_RS15900 9c14984908ac461055232aa235c29471 365 Pfam PF02195 ParB-like nuclease domain 86 174 3.7E-24 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS15900 9c14984908ac461055232aa235c29471 365 SUPERFAMILY SSF109709 167 276 7.19E-33 T 06-07-2017 LK06_RS30305 e81d87476d2e19a13b89df1840d9e24f 116 Gene3D G3DSA:3.10.180.10 9 112 4.7E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30305 e81d87476d2e19a13b89df1840d9e24f 116 SUPERFAMILY SSF54593 1 114 3.85E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS04545 6b4297d1065a818baf91d23ad3c8a632 387 SUPERFAMILY SSF56112 111 299 4.25E-22 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS04545 6b4297d1065a818baf91d23ad3c8a632 387 Pfam PF01636 Phosphotransferase enzyme family 124 277 1.9E-11 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS04545 6b4297d1065a818baf91d23ad3c8a632 387 Gene3D G3DSA:3.90.1200.10 157 296 2.4E-18 T 06-07-2017 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 28 269 1.2E-42 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 46 64 3.5E-12 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 168 181 3.5E-12 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 66 78 3.5E-12 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 259 278 3.5E-12 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 SUPERFAMILY SSF50621 249 391 4.19E-18 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 46 64 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 294 383 1.1E-7 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 Gene3D G3DSA:3.20.20.10 28 253 1.8E-53 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 Gene3D G3DSA:2.40.37.10 254 392 1.0E-15 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 SUPERFAMILY SSF51419 24 271 1.29E-54 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 PRINTS PR01182 Ornithine decarboxylase signature 88 112 2.9E-9 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 PRINTS PR01182 Ornithine decarboxylase signature 18 42 2.9E-9 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 PRINTS PR01182 Ornithine decarboxylase signature 44 71 2.9E-9 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 PRINTS PR01182 Ornithine decarboxylase signature 118 140 2.9E-9 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 LK06_RS26150 67f4b234255de8a90a4f0b8a52fea172 404 PRINTS PR01182 Ornithine decarboxylase signature 330 340 2.9E-9 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 LK06_RS17310 eaaa53460a40bdc0cf99c69093d7af7e 262 Pfam PF00440 Bacterial regulatory proteins, tetR family 49 92 5.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17310 eaaa53460a40bdc0cf99c69093d7af7e 262 SUPERFAMILY SSF46689 34 118 1.25E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS17310 eaaa53460a40bdc0cf99c69093d7af7e 262 Gene3D G3DSA:1.10.357.10 199 261 6.7E-62 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS17310 eaaa53460a40bdc0cf99c69093d7af7e 262 Gene3D G3DSA:1.10.357.10 36 165 6.7E-62 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS17310 eaaa53460a40bdc0cf99c69093d7af7e 262 SUPERFAMILY SSF48498 197 259 8.9E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS17310 eaaa53460a40bdc0cf99c69093d7af7e 262 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 9.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17310 eaaa53460a40bdc0cf99c69093d7af7e 262 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 9.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS22835 f2b53eb40e455d1006af221e122be6f1 645 Pfam PF02421 Ferrous iron transport protein B 17 174 2.3E-42 T 06-07-2017 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 LK06_RS22835 f2b53eb40e455d1006af221e122be6f1 645 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 39 57 9.8E-8 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS22835 f2b53eb40e455d1006af221e122be6f1 645 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 18 38 9.8E-8 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS22835 f2b53eb40e455d1006af221e122be6f1 645 SUPERFAMILY SSF52540 17 187 3.2E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22835 f2b53eb40e455d1006af221e122be6f1 645 Pfam PF07670 Nucleoside recognition 463 616 3.0E-22 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 LK06_RS22835 f2b53eb40e455d1006af221e122be6f1 645 Pfam PF07670 Nucleoside recognition 293 386 1.9E-12 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 LK06_RS22835 f2b53eb40e455d1006af221e122be6f1 645 Gene3D G3DSA:3.40.50.300 17 179 2.3E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22835 f2b53eb40e455d1006af221e122be6f1 645 Pfam PF07664 Ferrous iron transport protein B C terminus 405 456 5.7E-16 T 06-07-2017 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 SUPERFAMILY SSF51735 149 299 4.84E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 Gene3D G3DSA:3.90.180.10 12 54 9.6E-16 T 06-07-2017 IPR011032 GroES-like LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 Gene3D G3DSA:3.90.180.10 88 175 9.6E-16 T 06-07-2017 IPR011032 GroES-like LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 Gene3D G3DSA:3.40.50.720 176 290 9.8E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 409 529 6.3E-21 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 Gene3D G3DSA:3.40.50.720 405 535 3.3E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 SUPERFAMILY SSF51735 404 569 8.05E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 Pfam PF00107 Zinc-binding dehydrogenase 182 296 1.1E-14 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 Gene3D G3DSA:3.30.360.10 536 728 3.1E-27 T 06-07-2017 LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 SUPERFAMILY SSF50129 87 180 3.95E-17 T 06-07-2017 IPR011032 GroES-like LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 SUPERFAMILY SSF50129 7 55 3.95E-17 T 06-07-2017 IPR011032 GroES-like LK06_RS25900 80987e6772bb8b8fbe16e64bb17d2191 730 SUPERFAMILY SSF55347 564 692 1.85E-10 T 06-07-2017 LK06_RS18405 4828e4b31f12774ba34e33bbe1345cc5 214 SUPERFAMILY SSF109604 28 204 1.77E-34 T 06-07-2017 LK06_RS18405 4828e4b31f12774ba34e33bbe1345cc5 214 PIRSF PIRSF035170 1 214 4.8E-78 T 06-07-2017 IPR009218 Predicted HD phosphohydrolase LK06_RS18405 4828e4b31f12774ba34e33bbe1345cc5 214 Gene3D G3DSA:1.10.3210.10 38 142 1.7E-12 T 06-07-2017 IPR006674 HD domain LK06_RS28355 5eb9b4380de8e0dbbcdf8ddda16df7d1 362 Gene3D G3DSA:3.40.50.2000 203 355 3.4E-44 T 06-07-2017 LK06_RS28355 5eb9b4380de8e0dbbcdf8ddda16df7d1 362 Gene3D G3DSA:3.40.50.2000 3 202 6.3E-70 T 06-07-2017 LK06_RS28355 5eb9b4380de8e0dbbcdf8ddda16df7d1 362 SUPERFAMILY SSF53756 3 358 1.17E-100 T 06-07-2017 LK06_RS28355 5eb9b4380de8e0dbbcdf8ddda16df7d1 362 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 30 354 2.0E-100 T 06-07-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS28355 5eb9b4380de8e0dbbcdf8ddda16df7d1 362 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 355 3.3E-86 T 06-07-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 212 231 2.6E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 81 97 2.6E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 160 172 2.6E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 ProSitePatterns PS00761 Signal peptidases I signature 3. 217 230 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 Pfam PF10502 Signal peptidase, peptidase S26 139 251 3.5E-7 T 06-07-2017 IPR019533 Peptidase S26 LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 Pfam PF00717 Peptidase S24-like 88 130 1.5E-11 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 SUPERFAMILY SSF51306 80 128 8.37E-49 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 SUPERFAMILY SSF51306 155 264 8.37E-49 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 67 259 6.5E-42 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 Gene3D G3DSA:2.10.109.10 77 170 1.8E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS24445 5a557322bb8e5d1adcf08cd2325fc280 324 Gene3D G3DSA:2.10.109.10 212 264 1.8E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS21275 6c9b2d012ae7749620f40e052527d010 445 SUPERFAMILY SSF52540 69 391 3.97E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21275 6c9b2d012ae7749620f40e052527d010 445 Gene3D G3DSA:3.30.450.90 83 180 5.6E-38 T 06-07-2017 LK06_RS21275 6c9b2d012ae7749620f40e052527d010 445 Pfam PF00437 Type II/IV secretion system protein 86 362 1.6E-90 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 LK06_RS21275 6c9b2d012ae7749620f40e052527d010 445 Gene3D G3DSA:3.40.50.300 184 394 5.6E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25780 5f96cece8734591a12630ea3fbca850a 414 SUPERFAMILY SSF51905 3 111 9.26E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25780 5f96cece8734591a12630ea3fbca850a 414 SUPERFAMILY SSF51905 247 323 9.26E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25780 5f96cece8734591a12630ea3fbca850a 414 Gene3D G3DSA:3.50.50.60 3 119 1.4E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25780 5f96cece8734591a12630ea3fbca850a 414 Gene3D G3DSA:3.50.50.60 260 324 1.4E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25780 5f96cece8734591a12630ea3fbca850a 414 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 119 1.6E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25780 5f96cece8734591a12630ea3fbca850a 414 Gene3D G3DSA:3.50.50.60 139 252 4.6E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25780 5f96cece8734591a12630ea3fbca850a 414 SUPERFAMILY SSF51905 118 252 4.66E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS16470 6e81bd916a0b8ffcb0097eba389ba183 350 Pfam PF13452 N-terminal half of MaoC dehydratase 34 157 6.6E-15 T 06-07-2017 LK06_RS16470 6e81bd916a0b8ffcb0097eba389ba183 350 SUPERFAMILY SSF50249 211 329 2.74E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS16470 6e81bd916a0b8ffcb0097eba389ba183 350 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 226 257 2.7E-7 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal LK06_RS16470 6e81bd916a0b8ffcb0097eba389ba183 350 Gene3D G3DSA:3.10.129.10 33 163 8.3E-12 T 06-07-2017 IPR029069 HotDog domain LK06_RS16470 6e81bd916a0b8ffcb0097eba389ba183 350 SUPERFAMILY SSF54637 35 169 3.02E-14 T 06-07-2017 IPR029069 HotDog domain LK06_RS16470 6e81bd916a0b8ffcb0097eba389ba183 350 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 264 326 5.3E-22 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal LK06_RS20045 2f728997636d1f51436d10869ee0c866 123 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 84 8.0E-12 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 LK06_RS20045 2f728997636d1f51436d10869ee0c866 123 SUPERFAMILY SSF56214 3 122 3.92E-25 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS20045 2f728997636d1f51436d10869ee0c866 123 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 121 3.0E-24 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 LK06_RS20045 2f728997636d1f51436d10869ee0c866 123 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 103 2.3E-13 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS20045 2f728997636d1f51436d10869ee0c866 123 Gene3D G3DSA:3.90.470.20 1 122 1.3E-40 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS20045 2f728997636d1f51436d10869ee0c866 123 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 3 122 2.5E-20 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 LK06_RS20045 2f728997636d1f51436d10869ee0c866 123 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 123 22.475 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 LK06_RS14725 e94daa12af06794af0ecf037f1b8ce98 336 SMART SM00421 260 317 7.7E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14725 e94daa12af06794af0ecf037f1b8ce98 336 SUPERFAMILY SSF46894 255 324 2.04E-9 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS14725 e94daa12af06794af0ecf037f1b8ce98 336 Gene3D G3DSA:1.10.10.10 258 323 2.6E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21835 b158dac611a3be015a2144d74db18ec2 354 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 335 1.8E-20 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21835 b158dac611a3be015a2144d74db18ec2 354 SMART SM00382 48 247 4.4E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS21835 b158dac611a3be015a2144d74db18ec2 354 Pfam PF00005 ABC transporter 40 197 1.0E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS21835 b158dac611a3be015a2144d74db18ec2 354 Gene3D G3DSA:3.40.50.300 18 271 3.8E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21835 b158dac611a3be015a2144d74db18ec2 354 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS21835 b158dac611a3be015a2144d74db18ec2 354 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 309 3.7E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21835 b158dac611a3be015a2144d74db18ec2 354 SUPERFAMILY SSF52540 19 268 2.89E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31605 1077c51eb59765b61879dff37fcf10d4 219 SMART SM00855 3 157 2.2E-22 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS31605 1077c51eb59765b61879dff37fcf10d4 219 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 192 2.6E-60 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS31605 1077c51eb59765b61879dff37fcf10d4 219 Gene3D G3DSA:3.40.50.1240 2 198 4.1E-59 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS31605 1077c51eb59765b61879dff37fcf10d4 219 SUPERFAMILY SSF53254 2 198 1.18E-59 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS29560 4f12a832872bdf23f85ef2e21a58ca5e 460 Pfam PF00270 DEAD/DEAH box helicase 39 207 8.9E-44 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS29560 4f12a832872bdf23f85ef2e21a58ca5e 460 Gene3D G3DSA:3.40.50.300 225 370 1.2E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29560 4f12a832872bdf23f85ef2e21a58ca5e 460 Pfam PF00271 Helicase conserved C-terminal domain 251 349 8.8E-23 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS29560 4f12a832872bdf23f85ef2e21a58ca5e 460 SMART SM00490 268 349 2.7E-29 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS29560 4f12a832872bdf23f85ef2e21a58ca5e 460 SMART SM00487 34 234 1.1E-51 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS29560 4f12a832872bdf23f85ef2e21a58ca5e 460 SUPERFAMILY SSF52540 86 364 4.33E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29560 4f12a832872bdf23f85ef2e21a58ca5e 460 Gene3D G3DSA:3.40.50.300 12 224 7.8E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 Gene3D G3DSA:2.70.150.10 718 817 4.6E-25 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 Pfam PF00702 haloacid dehalogenase-like hydrolase 913 1194 4.8E-19 T 06-07-2017 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 919 925 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 Pfam PF00122 E1-E2 ATPase 672 908 7.4E-50 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 Gene3D G3DSA:1.20.1110.10 646 701 1.2E-56 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 Gene3D G3DSA:1.20.1110.10 1149 1414 1.2E-56 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 717 933 1.2E-28 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1128 1259 3.1E-28 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1152 1168 9.2E-15 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1180 1196 9.2E-15 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1212 1237 9.2E-15 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1036 1054 9.2E-15 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 Gene3D G3DSA:3.40.1110.10 907 940 5.0E-7 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1204 1216 1.9E-29 T 06-07-2017 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 757 771 1.9E-29 T 06-07-2017 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 917 931 1.9E-29 T 06-07-2017 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1101 1111 1.9E-29 T 06-07-2017 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1079 1090 1.9E-29 T 06-07-2017 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1180 1199 1.9E-29 T 06-07-2017 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 Gene3D G3DSA:3.40.1110.10 987 1083 1.1E-12 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 Pfam PF00689 Cation transporting ATPase, C-terminus 1265 1414 1.0E-14 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 SUPERFAMILY SSF81665 818 911 3.92E-49 T 06-07-2017 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 SUPERFAMILY SSF81665 642 704 3.92E-49 T 06-07-2017 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 SUPERFAMILY SSF81665 1230 1416 3.92E-49 T 06-07-2017 LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 SUPERFAMILY SSF56784 915 935 1.16E-43 T 06-07-2017 IPR023214 HAD-like domain LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 SUPERFAMILY SSF56784 1033 1284 1.16E-43 T 06-07-2017 IPR023214 HAD-like domain LK06_RS29865 9d6b1d2211b3b7e99cec4ee085555851 1434 SUPERFAMILY SSF81653 718 816 3.92E-23 T 06-07-2017 LK06_RS02350 f9663b9ebe93b85ad242091df5ba6e21 152 SUPERFAMILY SSF55874 24 137 5.75E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS02350 f9663b9ebe93b85ad242091df5ba6e21 152 Gene3D G3DSA:3.30.565.10 37 138 4.6E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS02350 f9663b9ebe93b85ad242091df5ba6e21 152 Pfam PF13581 Histidine kinase-like ATPase domain 11 132 3.1E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25095 0efa31591f00e77b3eaff4a262465423 135 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 9 91 1.6E-25 T 06-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 LK06_RS25095 0efa31591f00e77b3eaff4a262465423 135 Gene3D G3DSA:1.10.3420.10 3 128 1.1E-40 T 06-07-2017 IPR023292 NTP pyrophosphohydrolase-like domain LK06_RS25095 0efa31591f00e77b3eaff4a262465423 135 SUPERFAMILY SSF101386 37 87 1.25E-9 T 06-07-2017 LK06_RS01575 ca1144ec1189c501c7055839e9810246 288 SUPERFAMILY SSF69593 56 197 6.67E-23 T 06-07-2017 LK06_RS01575 ca1144ec1189c501c7055839e9810246 288 Gene3D G3DSA:3.40.1130.10 74 168 6.8E-5 T 06-07-2017 LK06_RS01575 ca1144ec1189c501c7055839e9810246 288 SMART SM00563 84 196 1.0E-30 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS01575 ca1144ec1189c501c7055839e9810246 288 Pfam PF01553 Acyltransferase 72 192 1.8E-21 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS27130 341c8df4f8e7119dca7d5ac297e225ea 297 Gene3D G3DSA:3.30.465.10 53 165 6.6E-32 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS27130 341c8df4f8e7119dca7d5ac297e225ea 297 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 2 165 2.3E-43 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 LK06_RS27130 341c8df4f8e7119dca7d5ac297e225ea 297 SMART SM01092 172 282 2.5E-19 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal LK06_RS27130 341c8df4f8e7119dca7d5ac297e225ea 297 SUPERFAMILY SSF55447 172 285 2.62E-19 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal LK06_RS27130 341c8df4f8e7119dca7d5ac297e225ea 297 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 173 280 4.4E-11 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal LK06_RS27130 341c8df4f8e7119dca7d5ac297e225ea 297 Gene3D G3DSA:3.30.390.50 173 284 1.2E-32 T 06-07-2017 LK06_RS27130 341c8df4f8e7119dca7d5ac297e225ea 297 SUPERFAMILY SSF56176 2 165 9.45E-47 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS27130 341c8df4f8e7119dca7d5ac297e225ea 297 Gene3D G3DSA:3.30.43.10 2 51 2.5E-14 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 228 1.9E-43 T 06-07-2017 LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 125 153 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 SUPERFAMILY SSF51735 2 228 4.47E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 185 0.007 T 06-07-2017 LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 Gene3D G3DSA:3.40.50.720 1 228 9.2E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 157 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 128 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 66 77 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 213 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 157 1.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 66 77 1.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06980 2e6e206780ee7e0fa4c51d3f41a2883a 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 126 1.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 Pfam PF11838 ERAP1-like C-terminal domain 536 845 3.6E-59 T 06-07-2017 IPR024571 ERAP1-like C-terminal domain LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 Gene3D G3DSA:1.10.390.10 308 457 8.6E-43 T 06-07-2017 LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 SUPERFAMILY SSF55486 206 456 4.25E-76 T 06-07-2017 LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 295 310 1.1E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 178 193 1.1E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 314 326 1.1E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 135 150 1.1E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 261 271 1.1E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 SUPERFAMILY SSF63737 6 195 1.7E-36 T 06-07-2017 LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 Pfam PF01433 Peptidase family M1 96 389 4.5E-72 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10040 96c7154ed0454783a4193e1f5607142d 858 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 851 0.0 T 06-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 LK06_RS03605 c04d58bc5e2bb02491f035f05fecca3a 145 SUPERFAMILY SSF50331 1 69 9.23E-20 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal LK06_RS03605 c04d58bc5e2bb02491f035f05fecca3a 145 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 68 1.6E-19 T 06-07-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 LK06_RS03605 c04d58bc5e2bb02491f035f05fecca3a 145 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 74 138 4.0E-18 T 06-07-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 LK06_RS03605 c04d58bc5e2bb02491f035f05fecca3a 145 Gene3D G3DSA:2.40.50.100 74 137 4.8E-22 T 06-07-2017 LK06_RS03605 c04d58bc5e2bb02491f035f05fecca3a 145 Gene3D G3DSA:2.40.50.100 1 67 5.8E-25 T 06-07-2017 LK06_RS03605 c04d58bc5e2bb02491f035f05fecca3a 145 SUPERFAMILY SSF50331 74 139 2.55E-17 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal LK06_RS03605 c04d58bc5e2bb02491f035f05fecca3a 145 Pfam PF03459 TOBE domain 4 65 9.9E-22 T 06-07-2017 IPR005116 Transport-associated OB, type 1 LK06_RS03605 c04d58bc5e2bb02491f035f05fecca3a 145 Pfam PF03459 TOBE domain 75 135 9.1E-17 T 06-07-2017 IPR005116 Transport-associated OB, type 1 LK06_RS14795 cd33baf6d43023d6aff64877c11b60e0 191 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 3.6E-64 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 LK06_RS14795 cd33baf6d43023d6aff64877c11b60e0 191 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 34.145 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 LK06_RS14795 cd33baf6d43023d6aff64877c11b60e0 191 Pfam PF00692 dUTPase 70 180 2.3E-10 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 LK06_RS14795 cd33baf6d43023d6aff64877c11b60e0 191 Gene3D G3DSA:2.70.40.10 2 182 1.9E-66 T 06-07-2017 IPR029054 dUTPase-like LK06_RS14795 cd33baf6d43023d6aff64877c11b60e0 191 SUPERFAMILY SSF51283 2 183 4.58E-57 T 06-07-2017 IPR029054 dUTPase-like LK06_RS25115 4d69a2aa9ff6dd30b654db53b8030777 508 SUPERFAMILY SSF102114 148 388 1.27E-59 T 06-07-2017 LK06_RS25115 4d69a2aa9ff6dd30b654db53b8030777 508 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 17 459 68.235 T 06-07-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 LK06_RS25115 4d69a2aa9ff6dd30b654db53b8030777 508 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 18 454 3.9E-153 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 LK06_RS25115 4d69a2aa9ff6dd30b654db53b8030777 508 SMART SM00729 162 381 3.7E-60 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS25115 4d69a2aa9ff6dd30b654db53b8030777 508 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 166 186 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 LK06_RS25115 4d69a2aa9ff6dd30b654db53b8030777 508 Pfam PF00919 Uncharacterized protein family UPF0004 19 119 3.3E-27 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 LK06_RS25115 4d69a2aa9ff6dd30b654db53b8030777 508 Gene3D G3DSA:3.80.30.20 162 393 4.0E-85 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe LK06_RS25115 4d69a2aa9ff6dd30b654db53b8030777 508 Pfam PF04055 Radical SAM superfamily 166 336 6.9E-32 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS25115 4d69a2aa9ff6dd30b654db53b8030777 508 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 19 455 3.6E-146 T 06-07-2017 LK06_RS28835 8c10e6f318daa4d0a7eb9c80ea5f0bf7 191 Pfam PF01590 GAF domain 43 177 1.4E-11 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS28835 8c10e6f318daa4d0a7eb9c80ea5f0bf7 191 SUPERFAMILY SSF55781 40 184 2.33E-22 T 06-07-2017 IPR029016 GAF domain-like LK06_RS28835 8c10e6f318daa4d0a7eb9c80ea5f0bf7 191 Gene3D G3DSA:3.30.450.40 49 184 9.1E-15 T 06-07-2017 IPR029016 GAF domain-like LK06_RS23780 3983d93912159d3a1beb1a3da41152e9 332 SUPERFAMILY SSF161098 107 318 1.87E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS23780 3983d93912159d3a1beb1a3da41152e9 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 330 2.3E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS23780 3983d93912159d3a1beb1a3da41152e9 332 Gene3D G3DSA:1.10.3720.10 105 327 7.0E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 Pfam PF14698 Argininosuccinate lyase C-terminal 372 437 8.1E-21 T 06-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 464 1.7E-184 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 4.5E-55 T 06-07-2017 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 4.5E-55 T 06-07-2017 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 4.5E-55 T 06-07-2017 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 PRINTS PR00145 Argininosuccinate lyase family signature 319 338 4.5E-55 T 06-07-2017 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 4.5E-55 T 06-07-2017 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 4.5E-55 T 06-07-2017 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 Gene3D G3DSA:1.10.275.10 9 114 5.5E-35 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 SUPERFAMILY SSF48557 13 462 2.04E-139 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 7.2E-27 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 7.2E-27 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 7.2E-27 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 7.2E-27 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 Gene3D G3DSA:1.10.40.30 384 439 2.8E-27 T 06-07-2017 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 Pfam PF00206 Lyase 21 309 5.6E-66 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 Gene3D G3DSA:1.20.200.10 115 383 1.7E-99 T 06-07-2017 LK06_RS04645 4d89c18781ad1d8dc0a106ffd14680e1 475 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 462 41.234 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS17320 baf5ac867929c679895ea17f5d6e1995 559 SUPERFAMILY SSF55874 469 553 3.4E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17320 baf5ac867929c679895ea17f5d6e1995 559 SMART SM00331 208 421 4.2E-36 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS17320 baf5ac867929c679895ea17f5d6e1995 559 Gene3D G3DSA:3.30.450.20 59 174 2.6E-9 T 06-07-2017 LK06_RS17320 baf5ac867929c679895ea17f5d6e1995 559 SUPERFAMILY SSF81606 224 420 4.71E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS17320 baf5ac867929c679895ea17f5d6e1995 559 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 238 421 2.6E-48 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS17320 baf5ac867929c679895ea17f5d6e1995 559 SUPERFAMILY SSF55785 59 157 3.02E-5 T 06-07-2017 IPR000014 PAS domain LK06_RS17320 baf5ac867929c679895ea17f5d6e1995 559 Pfam PF13581 Histidine kinase-like ATPase domain 445 536 6.6E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS10015 393bd4ecf3349f63ffa6b5078b3fc0e7 409 SUPERFAMILY SSF56601 262 363 1.16E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS10015 393bd4ecf3349f63ffa6b5078b3fc0e7 409 SUPERFAMILY SSF56601 14 233 1.16E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS10015 393bd4ecf3349f63ffa6b5078b3fc0e7 409 Pfam PF00144 Beta-lactamase 33 343 2.6E-56 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS10015 393bd4ecf3349f63ffa6b5078b3fc0e7 409 Gene3D G3DSA:3.40.710.10 42 360 8.5E-74 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS23900 e2291856a6670071032220e92fc9dac7 504 Pfam PF02637 GatB domain 357 499 1.8E-41 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 LK06_RS23900 e2291856a6670071032220e92fc9dac7 504 Pfam PF02934 GatB/GatE catalytic domain 20 314 2.7E-103 T 06-07-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 LK06_RS23900 e2291856a6670071032220e92fc9dac7 504 SUPERFAMILY SSF89095 357 499 7.72E-25 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 LK06_RS23900 e2291856a6670071032220e92fc9dac7 504 SUPERFAMILY SSF55931 19 321 6.21E-111 T 06-07-2017 LK06_RS23900 e2291856a6670071032220e92fc9dac7 504 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 16 499 1.3E-141 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 LK06_RS23900 e2291856a6670071032220e92fc9dac7 504 SMART SM00845 352 499 7.5E-57 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 LK06_RS23900 e2291856a6670071032220e92fc9dac7 504 Gene3D G3DSA:1.10.10.410 442 499 3.7E-5 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal LK06_RS23900 e2291856a6670071032220e92fc9dac7 504 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 16 500 36.287 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 LK06_RS23900 e2291856a6670071032220e92fc9dac7 504 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 165 179 - T 06-07-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 SMART SM00388 202 267 3.5E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 3.0E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 3.0E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 372 3.0E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 Gene3D G3DSA:3.30.565.10 272 397 2.5E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 SUPERFAMILY SSF47384 186 263 3.73E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 SUPERFAMILY SSF55874 270 397 4.98E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 263 2.1E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 Gene3D G3DSA:1.10.287.130 193 263 5.8E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 SMART SM00387 309 410 9.1E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 Pfam PF00672 HAMP domain 130 197 6.7E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS12030 74ff68c20cbdd62257f7b7ff2c168d91 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 394 1.8E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 SUPERFAMILY SSF81891 166 477 3.27E-67 T 06-07-2017 LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 TIGRFAM TIGR00277 HDIG: HDIG domain 267 344 2.6E-17 T 06-07-2017 IPR006675 HDIG domain LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 195 256 5.1E-19 T 06-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 Pfam PF01743 Poly A polymerase head domain 46 167 2.3E-31 T 06-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 Gene3D G3DSA:3.30.460.10 26 163 9.6E-44 T 06-07-2017 LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 SUPERFAMILY SSF81301 27 163 5.45E-37 T 06-07-2017 LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 Pfam PF01966 HD domain 270 364 8.7E-15 T 06-07-2017 IPR006674 HD domain LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 SMART SM00471 266 480 8.0E-5 T 06-07-2017 IPR003607 HD/PDEase domain LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 Gene3D G3DSA:1.10.3090.10 422 444 2.2E-58 T 06-07-2017 LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 Gene3D G3DSA:1.10.3090.10 166 354 2.2E-58 T 06-07-2017 LK06_RS15945 807918b3c3c5ea388193961b5e2b9134 480 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 17 477 2.1E-245 T 06-07-2017 IPR014065 tRNA adenylyltransferase LK06_RS03755 9024172d7ad7d3624a59f297d6157ede 144 SMART SM00960 18 108 9.3E-29 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS03755 9024172d7ad7d3624a59f297d6157ede 144 SUPERFAMILY SSF103196 11 137 1.57E-34 T 06-07-2017 LK06_RS03755 9024172d7ad7d3624a59f297d6157ede 144 Pfam PF03259 Roadblock/LC7 domain 17 107 1.0E-25 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS03755 9024172d7ad7d3624a59f297d6157ede 144 Gene3D G3DSA:3.30.450.30 11 135 4.2E-25 T 06-07-2017 LK06_RS03630 4bfac2993bfdb0859d3b58d17c874f57 157 Pfam PF02577 Bifunctional nuclease 6 128 1.4E-45 T 06-07-2017 IPR003729 Bifunctional nuclease domain GO:0004518 LK06_RS03630 4bfac2993bfdb0859d3b58d17c874f57 157 SUPERFAMILY SSF103256 3 136 1.44E-46 T 06-07-2017 IPR003729 Bifunctional nuclease domain GO:0004518 LK06_RS03970 194cabfeca2148ee03b156f537c4bf9e 152 SUPERFAMILY SSF54637 16 148 2.48E-28 T 06-07-2017 IPR029069 HotDog domain LK06_RS03970 194cabfeca2148ee03b156f537c4bf9e 152 Gene3D G3DSA:3.10.129.10 17 149 1.5E-31 T 06-07-2017 IPR029069 HotDog domain LK06_RS03970 194cabfeca2148ee03b156f537c4bf9e 152 Pfam PF03061 Thioesterase superfamily 30 114 2.2E-10 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 LK06_RS03095 177eb2328e8fb1fe8b72011a543b079b 288 Gene3D G3DSA:3.40.50.1820 7 281 4.0E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS03095 177eb2328e8fb1fe8b72011a543b079b 288 Pfam PF12697 Alpha/beta hydrolase family 29 273 1.3E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS03095 177eb2328e8fb1fe8b72011a543b079b 288 SUPERFAMILY SSF53474 6 281 9.38E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS09270 0aeb9e8b58a2cff4582aaa2d88db0c12 377 Gene3D G3DSA:1.10.1200.80 263 331 1.1E-16 T 06-07-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 LK06_RS09270 0aeb9e8b58a2cff4582aaa2d88db0c12 377 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 7 327 6.4E-109 T 06-07-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 LK06_RS09270 0aeb9e8b58a2cff4582aaa2d88db0c12 377 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 101 119 - T 06-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 LK06_RS09270 0aeb9e8b58a2cff4582aaa2d88db0c12 377 Pfam PF01207 Dihydrouridine synthase (Dus) 17 321 7.5E-93 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 LK06_RS09270 0aeb9e8b58a2cff4582aaa2d88db0c12 377 Gene3D G3DSA:3.20.20.70 14 255 1.1E-83 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS09270 0aeb9e8b58a2cff4582aaa2d88db0c12 377 SUPERFAMILY SSF51395 14 326 8.42E-77 T 06-07-2017 LK06_RS09270 0aeb9e8b58a2cff4582aaa2d88db0c12 377 PIRSF PIRSF006621 5 338 4.2E-99 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 SUPERFAMILY SSF55424 341 461 7.73E-34 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 449 1.3E-20 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 SUPERFAMILY SSF51905 156 336 2.26E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 Gene3D G3DSA:3.50.50.60 14 131 4.9E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 Gene3D G3DSA:3.50.50.60 132 332 7.1E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 SUPERFAMILY SSF51905 16 212 5.19E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 Gene3D G3DSA:3.30.390.30 353 462 1.9E-40 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 138 1.1E-18 T 06-07-2017 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 1.1E-18 T 06-07-2017 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 268 1.1E-18 T 06-07-2017 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 1.1E-18 T 06-07-2017 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 325 7.4E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 2.5E-17 T 06-07-2017 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 2.5E-17 T 06-07-2017 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 253 267 2.5E-17 T 06-07-2017 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 302 2.5E-17 T 06-07-2017 LK06_RS26635 2bc37110a996ee116759e6414efa73f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 16 38 2.5E-17 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2434 2608 8.0E-32 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SUPERFAMILY SSF52777 11 176 2.22E-35 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SMART SM00823 Phosphopantetheine attachment site 2726 2795 1.2E-10 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SMART SM00823 Phosphopantetheine attachment site 983 1054 1.4E-13 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:2.30.38.10 786 865 1.4E-25 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SUPERFAMILY SSF51735 2214 2421 3.11E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SUPERFAMILY SSF51735 2436 2642 1.38E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Pfam PF00668 Condensation domain 9 301 2.6E-43 T 06-07-2017 IPR001242 Condensation domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Pfam PF00668 Condensation domain 1072 1369 1.1E-57 T 06-07-2017 IPR001242 Condensation domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:3.40.50.720 2437 2610 1.1E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1009 1024 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SUPERFAMILY SSF52777 192 433 5.67E-39 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:1.10.1200.10 2717 2794 1.5E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:1.10.1200.10 986 1054 3.1E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:3.40.50.980 456 620 3.6E-43 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Pfam PF00501 AMP-binding enzyme 462 875 8.2E-100 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Pfam PF00501 AMP-binding enzyme 1678 2092 1.8E-63 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SMART SM01294 2723 2791 0.0027 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SUPERFAMILY SSF47336 982 1084 4.06E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 484 899 2.1E-134 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SUPERFAMILY SSF56801 1663 2194 7.46E-100 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SUPERFAMILY SSF52777 1074 1245 1.56E-45 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SUPERFAMILY SSF47336 2722 2792 1.44E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Pfam PF13745 HxxPF-repeated domain 1391 1486 1.4E-26 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Pfam PF13193 AMP-binding enzyme C-terminal domain 883 958 5.7E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SUPERFAMILY SSF56801 453 995 2.35E-158 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:3.40.50.980 1835 1994 4.7E-30 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:3.40.50.980 621 775 8.6E-49 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:3.40.50.980 1669 1834 3.6E-20 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:3.30.300.30 2086 2191 2.2E-12 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1829 1840 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:3.30.300.30 870 985 1.9E-37 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 SUPERFAMILY SSF52777 1258 1504 3.0E-53 T 06-07-2017 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Pfam PF00550 Phosphopantetheine attachment site 986 1047 1.4E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Pfam PF00550 Phosphopantetheine attachment site 2729 2791 2.9E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 ProSitePatterns PS00455 Putative AMP-binding domain signature. 611 622 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Pfam PF08659 KR domain 2434 2607 6.3E-42 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS31530 0c6e306ec15445193b8ea5f8d9ed853d 2842 Gene3D G3DSA:2.30.38.10 2012 2085 8.1E-22 T 06-07-2017 LK06_RS08040 e9b70df2db06cee4b04e8675c8623f39 188 SMART SM00347 35 139 2.7E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS08040 e9b70df2db06cee4b04e8675c8623f39 188 Pfam PF12802 MarR family 41 102 7.4E-10 T 06-07-2017 LK06_RS08040 e9b70df2db06cee4b04e8675c8623f39 188 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 1.6E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS08040 e9b70df2db06cee4b04e8675c8623f39 188 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 1.6E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS08040 e9b70df2db06cee4b04e8675c8623f39 188 PRINTS PR00598 Bacterial regulatory protein MarR family signature 129 149 1.6E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS08040 e9b70df2db06cee4b04e8675c8623f39 188 SUPERFAMILY SSF46785 16 150 3.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08040 e9b70df2db06cee4b04e8675c8623f39 188 Gene3D G3DSA:1.10.10.10 13 151 1.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29825 2f3ec5fdf07740f294eaedf86a34b502 324 Gene3D G3DSA:3.30.420.40 187 282 6.1E-4 T 06-07-2017 LK06_RS29825 2f3ec5fdf07740f294eaedf86a34b502 324 SUPERFAMILY SSF53067 120 304 2.02E-38 T 06-07-2017 LK06_RS29825 2f3ec5fdf07740f294eaedf86a34b502 324 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 72 277 3.2E-17 T 06-07-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 LK06_RS25370 63c8308e284cc9c070a2cf104141c00b 464 SUPERFAMILY SSF63411 19 232 4.22E-59 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LK06_RS25370 63c8308e284cc9c070a2cf104141c00b 464 Gene3D G3DSA:3.30.830.10 274 429 4.0E-17 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 LK06_RS25370 63c8308e284cc9c070a2cf104141c00b 464 Gene3D G3DSA:3.30.830.10 21 238 4.0E-60 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 LK06_RS25370 63c8308e284cc9c070a2cf104141c00b 464 SUPERFAMILY SSF63411 249 434 2.67E-26 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LK06_RS25370 63c8308e284cc9c070a2cf104141c00b 464 Pfam PF05193 Peptidase M16 inactive domain 187 366 2.9E-29 T 06-07-2017 IPR007863 Peptidase M16, C-terminal LK06_RS25370 63c8308e284cc9c070a2cf104141c00b 464 Pfam PF00675 Insulinase (Peptidase family M16) 28 147 5.2E-21 T 06-07-2017 IPR011765 Peptidase M16, N-terminal LK06_RS24175 3342d8e73f893716c5afdf22d0b2b43a 238 SMART SM00346 7 93 1.6E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS24175 3342d8e73f893716c5afdf22d0b2b43a 238 Gene3D G3DSA:1.10.10.10 3 73 5.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS24175 3342d8e73f893716c5afdf22d0b2b43a 238 SUPERFAMILY SSF46785 7 75 2.58E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS24175 3342d8e73f893716c5afdf22d0b2b43a 238 Pfam PF01614 Bacterial transcriptional regulator 125 232 1.0E-16 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal LK06_RS24175 3342d8e73f893716c5afdf22d0b2b43a 238 Gene3D G3DSA:3.30.450.40 74 234 2.5E-40 T 06-07-2017 IPR029016 GAF domain-like LK06_RS24175 3342d8e73f893716c5afdf22d0b2b43a 238 SUPERFAMILY SSF55781 62 234 1.11E-34 T 06-07-2017 IPR029016 GAF domain-like LK06_RS24175 3342d8e73f893716c5afdf22d0b2b43a 238 Pfam PF09339 IclR helix-turn-helix domain 10 57 1.2E-8 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS04165 2353a94277f3640f3f722825f1bf846c 363 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 8 360 35.932 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 LK06_RS04165 2353a94277f3640f3f722825f1bf846c 363 Gene3D G3DSA:3.40.50.1970 14 175 6.4E-54 T 06-07-2017 LK06_RS04165 2353a94277f3640f3f722825f1bf846c 363 SUPERFAMILY SSF56796 15 358 3.79E-96 T 06-07-2017 LK06_RS04165 2353a94277f3640f3f722825f1bf846c 363 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 19 346 7.6E-105 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 LK06_RS04165 2353a94277f3640f3f722825f1bf846c 363 Gene3D G3DSA:1.20.1090.10 178 357 2.7E-58 T 06-07-2017 LK06_RS04165 2353a94277f3640f3f722825f1bf846c 363 PIRSF PIRSF001455 9 362 3.0E-98 T 06-07-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 LK06_RS04165 2353a94277f3640f3f722825f1bf846c 363 Pfam PF01761 3-dehydroquinate synthase 71 327 7.8E-92 T 06-07-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 LK06_RS29000 c5df40dfd3eb9fdd9dc85d7118710745 437 SUPERFAMILY SSF53850 37 434 6.44E-66 T 06-07-2017 LK06_RS29000 c5df40dfd3eb9fdd9dc85d7118710745 437 Gene3D G3DSA:3.40.190.10 178 364 1.4E-31 T 06-07-2017 LK06_RS29000 c5df40dfd3eb9fdd9dc85d7118710745 437 Gene3D G3DSA:3.40.190.10 50 177 1.3E-22 T 06-07-2017 LK06_RS29000 c5df40dfd3eb9fdd9dc85d7118710745 437 Pfam PF01547 Bacterial extracellular solute-binding protein 65 349 5.6E-33 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 LK06_RS05720 098ec2c0883f7d4ebd746b04fbc3bebc 555 Pfam PF00117 Glutamine amidotransferase class-I 313 547 1.3E-48 T 06-07-2017 IPR017926 Glutamine amidotransferase LK06_RS05720 098ec2c0883f7d4ebd746b04fbc3bebc 555 Hamap MF_01227 CTP synthase [pyrG]. 14 552 50.309 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 LK06_RS05720 098ec2c0883f7d4ebd746b04fbc3bebc 555 SUPERFAMILY SSF52540 14 278 2.95E-117 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05720 098ec2c0883f7d4ebd746b04fbc3bebc 555 Gene3D G3DSA:3.40.50.880 300 552 4.9E-85 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS05720 098ec2c0883f7d4ebd746b04fbc3bebc 555 TIGRFAM TIGR00337 PyrG: CTP synthase 13 547 4.0E-229 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 LK06_RS05720 098ec2c0883f7d4ebd746b04fbc3bebc 555 Gene3D G3DSA:3.40.50.300 8 296 4.8E-131 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05720 098ec2c0883f7d4ebd746b04fbc3bebc 555 SUPERFAMILY SSF52317 301 551 3.95E-69 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS05720 098ec2c0883f7d4ebd746b04fbc3bebc 555 Pfam PF06418 CTP synthase N-terminus 15 278 4.9E-122 T 06-07-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 LK06_RS14605 b40d1dc1dbe309673845a51c1a744a08 139 Pfam PF11349 Protein of unknown function (DUF3151) 10 135 3.8E-55 T 06-07-2017 IPR014487 Protein of unknown function DUF3151 LK06_RS14605 b40d1dc1dbe309673845a51c1a744a08 139 PIRSF PIRSF017349 1 139 4.0E-55 T 06-07-2017 IPR014487 Protein of unknown function DUF3151 LK06_RS14560 4b3fc7ad512d7493745d1000037aaaf2 303 Pfam PF13732 Domain of unknown function (DUF4162) 212 289 1.2E-6 T 06-07-2017 IPR025302 Domain of unknown function DUF4162 LK06_RS14560 4b3fc7ad512d7493745d1000037aaaf2 303 SUPERFAMILY SSF52540 4 218 1.14E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14560 4b3fc7ad512d7493745d1000037aaaf2 303 SMART SM00382 29 215 6.6E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS14560 4b3fc7ad512d7493745d1000037aaaf2 303 Gene3D G3DSA:3.40.50.300 2 219 6.3E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14560 4b3fc7ad512d7493745d1000037aaaf2 303 Pfam PF00005 ABC transporter 20 159 8.9E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS27525 de795c78f60cda5147d868b18565b071 202 SUPERFAMILY SSF53448 10 198 2.48E-31 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS27525 de795c78f60cda5147d868b18565b071 202 Gene3D G3DSA:3.90.550.10 10 201 2.5E-32 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS27525 de795c78f60cda5147d868b18565b071 202 Pfam PF12804 MobA-like NTP transferase domain 13 174 3.9E-36 T 06-07-2017 IPR025877 MobA-like NTP transferase LK06_RS26450 81be478974498cc9e9ae23e86c44a734 1258 Gene3D G3DSA:2.60.120.200 1090 1254 1.2E-20 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain LK06_RS26450 81be478974498cc9e9ae23e86c44a734 1258 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1095 1254 2.3E-19 T 06-07-2017 LK06_RS26450 81be478974498cc9e9ae23e86c44a734 1258 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 165 352 6.0E-17 T 06-07-2017 LK06_RS26450 81be478974498cc9e9ae23e86c44a734 1258 SUPERFAMILY SSF49899 1037 1255 2.14E-21 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain LK06_RS02245 be0f0370badf91edb8fbce846e14dcad 242 Gene3D G3DSA:3.40.50.880 23 212 8.5E-20 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS02245 be0f0370badf91edb8fbce846e14dcad 242 SUPERFAMILY SSF52317 23 214 3.0E-20 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS02245 be0f0370badf91edb8fbce846e14dcad 242 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 8 202 2.3E-37 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 LK06_RS13145 d3453b5d6951ef6afa2963c86abdfa3e 367 Pfam PF03432 Relaxase/Mobilisation nuclease domain 95 274 3.0E-6 T 06-07-2017 IPR005094 Endonuclease relaxase, MobA/VirD2 LK06_RS28555 92a9079bf95d3d1538764b459fff0ff0 365 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 3.6E-16 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS28555 92a9079bf95d3d1538764b459fff0ff0 365 Gene3D G3DSA:3.40.50.2300 58 193 2.5E-25 T 06-07-2017 LK06_RS28555 92a9079bf95d3d1538764b459fff0ff0 365 Gene3D G3DSA:1.10.260.40 7 57 8.5E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS28555 92a9079bf95d3d1538764b459fff0ff0 365 SUPERFAMILY SSF47413 7 64 1.39E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS28555 92a9079bf95d3d1538764b459fff0ff0 365 SMART SM00354 7 77 1.5E-23 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS28555 92a9079bf95d3d1538764b459fff0ff0 365 Gene3D G3DSA:3.40.50.2300 194 326 1.3E-47 T 06-07-2017 LK06_RS28555 92a9079bf95d3d1538764b459fff0ff0 365 Pfam PF13377 Periplasmic binding protein-like domain 188 335 2.8E-32 T 06-07-2017 LK06_RS28555 92a9079bf95d3d1538764b459fff0ff0 365 SUPERFAMILY SSF53822 80 334 4.12E-57 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS23360 2ee8d761b338ce33b4ecc593efc3115a 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 60 1.7E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23360 2ee8d761b338ce33b4ecc593efc3115a 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23360 2ee8d761b338ce33b4ecc593efc3115a 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 3.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23360 2ee8d761b338ce33b4ecc593efc3115a 213 Gene3D G3DSA:1.10.10.60 6 58 8.5E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS23360 2ee8d761b338ce33b4ecc593efc3115a 213 Gene3D G3DSA:1.10.357.10 59 193 1.2E-13 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS23360 2ee8d761b338ce33b4ecc593efc3115a 213 SUPERFAMILY SSF46689 5 83 3.24E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS17115 e63da4ff1a3fc49487bdd2b716360e68 701 SMART SM00490 292 373 2.0E-29 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS17115 e63da4ff1a3fc49487bdd2b716360e68 701 Pfam PF00271 Helicase conserved C-terminal domain 275 373 9.5E-23 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS17115 e63da4ff1a3fc49487bdd2b716360e68 701 Gene3D G3DSA:3.40.50.300 31 247 3.9E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17115 e63da4ff1a3fc49487bdd2b716360e68 701 Gene3D G3DSA:3.40.50.300 248 398 5.2E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17115 e63da4ff1a3fc49487bdd2b716360e68 701 Pfam PF00270 DEAD/DEAH box helicase 63 231 1.4E-44 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS17115 e63da4ff1a3fc49487bdd2b716360e68 701 SUPERFAMILY SSF52540 110 394 7.72E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17115 e63da4ff1a3fc49487bdd2b716360e68 701 SMART SM00487 58 258 1.1E-48 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS01430 e3716eb037781bbdc1aee8ddb4c709aa 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 2.1E-17 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS01430 e3716eb037781bbdc1aee8ddb4c709aa 220 SUPERFAMILY SSF52172 2 124 9.68E-33 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS01430 e3716eb037781bbdc1aee8ddb4c709aa 220 SUPERFAMILY SSF46894 123 219 2.1E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS01430 e3716eb037781bbdc1aee8ddb4c709aa 220 SMART SM00448 3 113 5.0E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS01430 e3716eb037781bbdc1aee8ddb4c709aa 220 SMART SM00862 144 219 7.6E-17 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS01430 e3716eb037781bbdc1aee8ddb4c709aa 220 Gene3D G3DSA:3.40.50.2300 2 121 1.2E-31 T 06-07-2017 LK06_RS01430 e3716eb037781bbdc1aee8ddb4c709aa 220 Pfam PF00072 Response regulator receiver domain 5 113 2.2E-18 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS01430 e3716eb037781bbdc1aee8ddb4c709aa 220 Gene3D G3DSA:1.10.10.10 124 219 1.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 Gene3D G3DSA:3.50.50.60 30 134 2.2E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 Gene3D G3DSA:3.50.50.60 167 305 2.2E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 419 518 1.2E-12 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 390 400 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 105 117 6.6E-25 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 59 71 6.6E-25 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 30 42 6.6E-25 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 43 53 6.6E-25 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 347 353 6.6E-25 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 385 397 6.6E-25 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 Pfam PF01266 FAD dependent oxidoreductase 31 397 3.7E-47 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS00455 6a795a5caaf2591492705a0db051fb08 528 SUPERFAMILY SSF51905 30 319 1.11E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS11400 d9f1946f866d7cf8974272f628701c46 680 SUPERFAMILY SSF47741 519 589 1.44E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LK06_RS11400 d9f1946f866d7cf8974272f628701c46 680 Gene3D G3DSA:1.10.150.120 510 593 8.6E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LK06_RS11400 d9f1946f866d7cf8974272f628701c46 680 Pfam PF01799 [2Fe-2S] binding domain 508 581 2.4E-23 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LK06_RS11400 d9f1946f866d7cf8974272f628701c46 680 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 474 482 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LK06_RS11400 d9f1946f866d7cf8974272f628701c46 680 Gene3D G3DSA:3.10.20.30 437 509 3.6E-25 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS11400 d9f1946f866d7cf8974272f628701c46 680 SUPERFAMILY SSF54292 440 522 7.14E-18 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 464 1.0E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 SUPERFAMILY SSF158472 197 247 2.62E-7 T 06-07-2017 LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 SUPERFAMILY SSF47384 233 311 9.22E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 SUPERFAMILY SSF55874 303 464 4.71E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 Gene3D G3DSA:3.30.565.10 320 465 3.7E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 SMART SM00304 196 249 2.0E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 5.4E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 5.4E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 311 6.8E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 Pfam PF00672 HAMP domain 179 245 8.2E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 SMART SM00388 250 313 6.9E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 Gene3D G3DSA:1.10.287.130 240 308 5.9E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25085 f3f188ef9cddffabe1534d4ec6fe7945 472 SMART SM00387 355 465 7.2E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00870 c791a973384573b070e46e30e91300fe 233 Gene3D G3DSA:3.40.50.300 7 208 4.1E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00870 c791a973384573b070e46e30e91300fe 233 SUPERFAMILY SSF52540 19 209 2.38E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 Pfam PF00117 Glutamine amidotransferase class-I 16 196 8.7E-41 T 06-07-2017 IPR017926 Glutamine amidotransferase LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 SUPERFAMILY SSF52317 14 205 1.44E-51 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 Pfam PF00958 GMP synthase C terminal domain 433 525 9.6E-39 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 11 526 54.0 T 06-07-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 55 69 1.0E-5 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 14 28 1.0E-5 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 85 101 1.0E-5 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 85 96 1.1E-7 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 58 67 1.1E-7 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 174 187 1.1E-7 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 SUPERFAMILY SSF52402 190 446 1.32E-58 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 SUPERFAMILY SSF54810 405 526 4.45E-47 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 209 526 4.3E-149 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 Gene3D G3DSA:3.40.50.880 11 196 8.4E-56 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 14 196 1.8E-72 T 06-07-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 Pfam PF02540 NAD synthase 220 293 3.7E-7 T 06-07-2017 IPR022310 NAD/GMP synthase LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 Gene3D G3DSA:3.30.300.10 401 526 4.9E-49 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 Gene3D G3DSA:3.40.50.620 205 400 5.1E-58 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 PRINTS PR00097 Anthranilate synthase component II signature 58 67 1.0E-5 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 PRINTS PR00097 Anthranilate synthase component II signature 174 187 1.0E-5 T 06-07-2017 LK06_RS20225 d13f5fa8165d392b8cb2836e07e75337 526 PRINTS PR00097 Anthranilate synthase component II signature 85 96 1.0E-5 T 06-07-2017 LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 SUPERFAMILY SSF46785 2 62 3.54E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 SUPERFAMILY SSF54909 64 142 1.88E-12 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 SMART SM00344 2 109 4.0E-27 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 Gene3D G3DSA:3.30.70.920 55 134 2.7E-19 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.0E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.0E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.0E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 Gene3D G3DSA:1.10.10.10 4 54 1.1E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 2.1E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS04035 f7f36e65ae7f1ce36cceb08cb312c557 150 Pfam PF01037 Lrp/AsnC ligand binding domain 68 138 3.7E-14 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS08515 8ce357b3e465fccc9ac41cd936e4fedf 396 Gene3D G3DSA:2.40.50.100 374 388 8.4E-9 T 06-07-2017 LK06_RS08515 8ce357b3e465fccc9ac41cd936e4fedf 396 Gene3D G3DSA:2.40.50.100 240 284 8.4E-9 T 06-07-2017 LK06_RS08515 8ce357b3e465fccc9ac41cd936e4fedf 396 SMART SM00382 29 220 3.9E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS08515 8ce357b3e465fccc9ac41cd936e4fedf 396 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS08515 8ce357b3e465fccc9ac41cd936e4fedf 396 Gene3D G3DSA:3.40.50.300 4 235 1.9E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08515 8ce357b3e465fccc9ac41cd936e4fedf 396 SUPERFAMILY SSF50331 237 388 1.8E-18 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal LK06_RS08515 8ce357b3e465fccc9ac41cd936e4fedf 396 Pfam PF00005 ABC transporter 21 162 5.1E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS08515 8ce357b3e465fccc9ac41cd936e4fedf 396 Gene3D G3DSA:2.40.50.140 285 373 8.6E-7 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS08515 8ce357b3e465fccc9ac41cd936e4fedf 396 SUPERFAMILY SSF52540 4 244 3.41E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 9 26 7.2E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 7.2E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 59 86 7.2E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 7.2E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 7.2E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 7.2E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 5 325 38.428 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 Gene3D G3DSA:3.40.50.720 3 186 5.7E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 163 1.4E-51 T 06-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 PIRSF PIRSF000114 2 335 1.3E-98 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 SUPERFAMILY SSF51735 7 182 7.49E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 Gene3D G3DSA:1.10.1040.10 187 329 7.5E-54 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 SUPERFAMILY SSF48179 182 334 3.51E-54 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 323 8.7E-49 T 06-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS24215 0ff0a60be2b1258f06b7e06056584e3d 336 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 LK06_RS09490 4f42adbe6230af61f56c7ff232adb946 377 Gene3D G3DSA:3.20.20.70 1 72 1.7E-71 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS09490 4f42adbe6230af61f56c7ff232adb946 377 Gene3D G3DSA:3.20.20.70 109 351 1.7E-71 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS09490 4f42adbe6230af61f56c7ff232adb946 377 SUPERFAMILY SSF51412 2 72 7.78E-61 T 06-07-2017 LK06_RS09490 4f42adbe6230af61f56c7ff232adb946 377 SUPERFAMILY SSF51412 114 362 7.78E-61 T 06-07-2017 LK06_RS09490 4f42adbe6230af61f56c7ff232adb946 377 Pfam PF03060 Nitronate monooxygenase 3 357 6.3E-113 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 LK06_RS18620 630ba8a18d83f59e5b89b62d82731cee 704 Pfam PF00664 ABC transporter transmembrane region 37 302 9.6E-41 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS18620 630ba8a18d83f59e5b89b62d82731cee 704 SMART SM00382 377 563 5.1E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS18620 630ba8a18d83f59e5b89b62d82731cee 704 SUPERFAMILY SSF52540 345 587 1.54E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18620 630ba8a18d83f59e5b89b62d82731cee 704 SUPERFAMILY SSF90123 22 337 4.05E-68 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS18620 630ba8a18d83f59e5b89b62d82731cee 704 Gene3D G3DSA:1.20.1560.10 21 338 6.3E-71 T 06-07-2017 LK06_RS18620 630ba8a18d83f59e5b89b62d82731cee 704 Gene3D G3DSA:3.40.50.300 350 582 1.0E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18620 630ba8a18d83f59e5b89b62d82731cee 704 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS18620 630ba8a18d83f59e5b89b62d82731cee 704 Pfam PF00005 ABC transporter 368 516 5.1E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS30890 e076035679464bcabad43b476b15337b 248 SMART SM00849 19 228 1.6E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS30890 e076035679464bcabad43b476b15337b 248 SUPERFAMILY SSF56281 3 236 5.11E-42 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS30890 e076035679464bcabad43b476b15337b 248 Pfam PF00753 Metallo-beta-lactamase superfamily 19 228 4.2E-29 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS30890 e076035679464bcabad43b476b15337b 248 Gene3D G3DSA:3.60.15.10 3 237 1.6E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS07480 042e2079ef11a31f18d3c8a2e63b91bb 331 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LK06_RS07480 042e2079ef11a31f18d3c8a2e63b91bb 331 Gene3D G3DSA:3.40.50.720 118 299 9.2E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS07480 042e2079ef11a31f18d3c8a2e63b91bb 331 Gene3D G3DSA:3.40.50.720 13 117 4.7E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS07480 042e2079ef11a31f18d3c8a2e63b91bb 331 SUPERFAMILY SSF51735 101 297 1.32E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS07480 042e2079ef11a31f18d3c8a2e63b91bb 331 SUPERFAMILY SSF52283 2 133 4.46E-30 T 06-07-2017 LK06_RS07480 042e2079ef11a31f18d3c8a2e63b91bb 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 327 1.0E-25 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 LK06_RS07480 042e2079ef11a31f18d3c8a2e63b91bb 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 296 2.0E-47 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LK06_RS07480 042e2079ef11a31f18d3c8a2e63b91bb 331 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.4E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.4E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.4E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.4E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.4E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.4E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 2.3E-55 T 06-07-2017 LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 SUPERFAMILY SSF51735 11 254 1.66E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02750 47d37fd318747dee22270128c2e9804f 259 Gene3D G3DSA:3.40.50.720 8 255 1.0E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 Gene3D G3DSA:1.10.275.10 343 431 2.0E-23 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 341 784 1.6E-127 T 06-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 Pfam PF00206 Lyase 397 630 2.0E-20 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 Gene3D G3DSA:1.20.200.10 432 781 1.8E-81 T 06-07-2017 LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 SUPERFAMILY SSF103473 18 229 8.37E-18 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 Pfam PF10397 Adenylosuccinate lyase C-terminus 700 782 7.0E-11 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 PRINTS PR00149 Fumarate lyase superfamily signature 428 446 8.6E-11 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 PRINTS PR00149 Fumarate lyase superfamily signature 567 594 8.6E-11 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 PRINTS PR00149 Fumarate lyase superfamily signature 473 491 8.6E-11 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 PRINTS PR00149 Fumarate lyase superfamily signature 610 626 8.6E-11 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 Gene3D G3DSA:1.20.1250.20 33 193 1.9E-11 T 06-07-2017 LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 SMART SM00998 699 785 4.4E-20 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 Pfam PF05977 Transmembrane secretion effector 46 238 9.9E-15 T 06-07-2017 IPR010290 Transmembrane secretion effector LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 SUPERFAMILY SSF48557 340 786 1.73E-81 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 LK06_RS02825 ae26fb64d6964c5023408daf2ce758da 807 ProSitePatterns PS00163 Fumarate lyases signature. 610 619 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 LK06_RS31535 08ae9c62aa3bf4e0542e956566e04d2b 432 Pfam PF00668 Condensation domain 76 141 1.5E-4 T 06-07-2017 IPR001242 Condensation domain LK06_RS31535 08ae9c62aa3bf4e0542e956566e04d2b 432 SUPERFAMILY SSF52777 194 422 7.78E-35 T 06-07-2017 LK06_RS31535 08ae9c62aa3bf4e0542e956566e04d2b 432 Pfam PF16911 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus 298 414 1.5E-26 T 06-07-2017 IPR031641 Phthiocerol/phthiodiolone dimycocerosyl transferase, C-terminal LK06_RS31535 08ae9c62aa3bf4e0542e956566e04d2b 432 SUPERFAMILY SSF52777 17 144 1.56E-15 T 06-07-2017 LK06_RS16495 8bdbb26e2f82882bfd133ac1ae769164 551 Pfam PF00501 AMP-binding enzyme 35 445 1.1E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS16495 8bdbb26e2f82882bfd133ac1ae769164 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 531 4.8E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS16495 8bdbb26e2f82882bfd133ac1ae769164 551 SUPERFAMILY SSF56801 18 543 1.57E-136 T 06-07-2017 LK06_RS16495 8bdbb26e2f82882bfd133ac1ae769164 551 Gene3D G3DSA:2.30.38.10 358 439 2.7E-18 T 06-07-2017 LK06_RS16495 8bdbb26e2f82882bfd133ac1ae769164 551 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS16495 8bdbb26e2f82882bfd133ac1ae769164 551 Gene3D G3DSA:3.40.50.980 191 344 2.1E-37 T 06-07-2017 LK06_RS16495 8bdbb26e2f82882bfd133ac1ae769164 551 Gene3D G3DSA:3.40.50.980 47 190 7.0E-29 T 06-07-2017 LK06_RS16495 8bdbb26e2f82882bfd133ac1ae769164 551 Gene3D G3DSA:3.30.300.30 440 541 2.7E-29 T 06-07-2017 LK06_RS23500 62659ff94cce3055f3a25acac212b37c 112 Pfam PF12823 Domain of unknown function (DUF3817) 6 95 4.8E-28 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane LK06_RS23500 62659ff94cce3055f3a25acac212b37c 112 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 94 9.9E-27 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane LK06_RS15885 154e629c32a0363a1e116c6fee12ee1d 170 SUPERFAMILY SSF82708 124 169 9.42E-12 T 06-07-2017 IPR001374 R3H domain GO:0003676 LK06_RS15885 154e629c32a0363a1e116c6fee12ee1d 170 SMART SM00393 92 170 2.9E-28 T 06-07-2017 IPR001374 R3H domain GO:0003676 LK06_RS15885 154e629c32a0363a1e116c6fee12ee1d 170 Gene3D G3DSA:3.30.300.120 20 102 1.0E-21 T 06-07-2017 LK06_RS15885 154e629c32a0363a1e116c6fee12ee1d 170 Gene3D G3DSA:3.30.1370.50 103 169 4.1E-24 T 06-07-2017 IPR001374 R3H domain GO:0003676 LK06_RS15885 154e629c32a0363a1e116c6fee12ee1d 170 Pfam PF01424 R3H domain 112 167 7.3E-15 T 06-07-2017 IPR001374 R3H domain GO:0003676 LK06_RS19745 baf5e078d0dddd1328d4b30502560feb 369 PIRSF PIRSF000808 34 369 1.0E-102 T 06-07-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 LK06_RS19745 baf5e078d0dddd1328d4b30502560feb 369 Gene3D G3DSA:3.30.428.10 180 367 1.6E-44 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS19745 baf5e078d0dddd1328d4b30502560feb 369 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 200 364 5.3E-12 T 06-07-2017 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 LK06_RS19745 baf5e078d0dddd1328d4b30502560feb 369 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 103 178 2.4E-26 T 06-07-2017 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 LK06_RS19745 baf5e078d0dddd1328d4b30502560feb 369 SUPERFAMILY SSF54197 183 367 4.11E-29 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS19745 baf5e078d0dddd1328d4b30502560feb 369 SUPERFAMILY SSF54197 37 179 4.64E-47 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS19745 baf5e078d0dddd1328d4b30502560feb 369 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 154 171 - T 06-07-2017 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 LK06_RS19745 baf5e078d0dddd1328d4b30502560feb 369 Gene3D G3DSA:3.30.428.10 64 177 1.1E-33 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 SUPERFAMILY SSF50621 303 461 1.21E-47 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 93 111 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 44 461 8.1E-145 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 Gene3D G3DSA:3.20.20.10 72 314 1.3E-92 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 267 280 - T 06-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 200 209 2.3E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 429 451 2.3E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 346 364 2.3E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 111 128 2.3E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 334 438 1.7E-15 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 52 462 39.808 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 SUPERFAMILY SSF51419 63 328 3.93E-78 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 419 432 4.0E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 113 125 4.0E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 317 336 4.0E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 93 111 4.0E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 228 241 4.0E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 71 327 1.5E-64 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 LK06_RS23205 f8bde49c91209c6cfdc10245f4092254 463 Gene3D G3DSA:2.40.37.10 315 461 3.8E-47 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 Pfam PF04055 Radical SAM superfamily 536 696 2.5E-14 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 Pfam PF04055 Radical SAM superfamily 77 259 1.1E-13 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 Hamap MF_01612 FO synthase subunit 2 [cofH]. 475 839 48.589 T 06-07-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 SMART SM00729 73 310 6.0E-5 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 SUPERFAMILY SSF102114 30 375 2.62E-36 T 06-07-2017 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 494 838 1.8E-161 T 06-07-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 528 836 1.3E-109 T 06-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 Hamap MF_01611 FO synthase subunit 1 [cofG]. 69 400 50.529 T 06-07-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 SUPERFAMILY SSF102114 492 802 1.05E-49 T 06-07-2017 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 Gene3D G3DSA:3.20.20.70 492 826 2.1E-76 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 Gene3D G3DSA:3.20.20.70 29 361 1.2E-64 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS19010 ba6e5371cbdb265a06012fff9976c955 861 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 70 398 5.3E-144 T 06-07-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 LK06_RS05340 bad52a00329aee066bb397d2f49d63ed 383 SUPERFAMILY SSF47203 227 379 3.38E-56 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS05340 bad52a00329aee066bb397d2f49d63ed 383 Gene3D G3DSA:1.20.140.10 219 379 4.2E-67 T 06-07-2017 LK06_RS05340 bad52a00329aee066bb397d2f49d63ed 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 5.6E-30 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS05340 bad52a00329aee066bb397d2f49d63ed 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 2.7E-36 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS05340 bad52a00329aee066bb397d2f49d63ed 383 Gene3D G3DSA:2.40.110.10 121 218 1.1E-41 T 06-07-2017 LK06_RS05340 bad52a00329aee066bb397d2f49d63ed 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 3.2E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS05340 bad52a00329aee066bb397d2f49d63ed 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS05340 bad52a00329aee066bb397d2f49d63ed 383 SUPERFAMILY SSF56645 2 241 5.5E-89 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS05340 bad52a00329aee066bb397d2f49d63ed 383 Gene3D G3DSA:1.10.540.10 2 119 2.7E-40 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS05340 bad52a00329aee066bb397d2f49d63ed 383 PIRSF PIRSF016578 4 380 2.2E-20 T 06-07-2017 LK06_RS24510 932fad0232e4a194cb36075ab178f1e6 185 Gene3D G3DSA:1.10.132.20 66 185 2.7E-41 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 LK06_RS24510 932fad0232e4a194cb36075ab178f1e6 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 5.2E-64 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 LK06_RS24510 932fad0232e4a194cb36075ab178f1e6 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.055 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 LK06_RS24510 932fad0232e4a194cb36075ab178f1e6 185 Pfam PF01765 Ribosome recycling factor 21 183 5.5E-59 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 LK06_RS24510 932fad0232e4a194cb36075ab178f1e6 185 SUPERFAMILY SSF55194 3 184 7.2E-68 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 LK06_RS28720 db95be2ffe5de61fd8a3d557ecfc7e88 302 Gene3D G3DSA:1.10.600.10 21 288 9.7E-49 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS28720 db95be2ffe5de61fd8a3d557ecfc7e88 302 SUPERFAMILY SSF48576 21 299 1.73E-60 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS28720 db95be2ffe5de61fd8a3d557ecfc7e88 302 Pfam PF00494 Squalene/phytoene synthase 21 286 3.6E-69 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 LK06_RS28720 db95be2ffe5de61fd8a3d557ecfc7e88 302 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 20 294 4.7E-99 T 06-07-2017 IPR017827 Squalene synthase HpnC LK06_RS28765 835056bd4f36f9be5bca04bf59758565 461 SUPERFAMILY SSF53383 26 437 7.48E-108 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS28765 835056bd4f36f9be5bca04bf59758565 461 Pfam PF00202 Aminotransferase class-III 40 435 3.0E-87 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS28765 835056bd4f36f9be5bca04bf59758565 461 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 233 271 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS28765 835056bd4f36f9be5bca04bf59758565 461 Gene3D G3DSA:3.40.640.10 76 322 5.5E-70 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS28765 835056bd4f36f9be5bca04bf59758565 461 Gene3D G3DSA:3.90.1150.10 323 437 1.6E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS28765 835056bd4f36f9be5bca04bf59758565 461 Gene3D G3DSA:3.90.1150.10 22 75 1.6E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 Gene3D G3DSA:1.10.287.130 301 359 1.1E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 SMART SM00387 405 517 3.9E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 Gene3D G3DSA:3.30.450.20 26 162 8.7E-42 T 06-07-2017 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 SMART SM00091 207 272 4.7E-4 T 06-07-2017 IPR000014 PAS domain LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 SUPERFAMILY SSF55785 210 269 2.72E-5 T 06-07-2017 IPR000014 PAS domain LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 Gene3D G3DSA:3.30.450.20 208 300 2.0E-7 T 06-07-2017 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 406 516 1.1E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 SUPERFAMILY SSF103190 30 161 1.02E-28 T 06-07-2017 IPR029151 Periplasmic sensor domain-like LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 495 4.9E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 458 4.9E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 514 4.9E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 Pfam PF17203 Single cache domain 3 30 162 1.9E-19 T 06-07-2017 IPR033463 Single cache domain 3 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 310 357 1.4E-9 T 06-07-2017 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 SUPERFAMILY SSF55874 384 515 1.57E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 SUPERFAMILY SSF55890 310 379 6.8E-10 T 06-07-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 Pfam PF00989 PAS fold 208 245 3.2E-6 T 06-07-2017 IPR013767 PAS fold GO:0006355 LK06_RS25340 1b0ca22628426934678f26b7a7061d71 520 Gene3D G3DSA:3.30.565.10 382 516 4.6E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS19230 e4c3939fde08677fc79dd20a3c80c6ba 65 SUPERFAMILY SSF55331 2 61 3.66E-18 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily LK06_RS19230 e4c3939fde08677fc79dd20a3c80c6ba 65 Gene3D G3DSA:3.30.429.20 1 59 6.2E-22 T 06-07-2017 LK06_RS19230 e4c3939fde08677fc79dd20a3c80c6ba 65 Pfam PF01361 Tautomerase enzyme 2 60 2.7E-17 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 LK06_RS08350 f55c7215ab7f522c19c9aa44e73a7767 129 SUPERFAMILY SSF101386 31 122 8.41E-10 T 06-07-2017 LK06_RS08350 f55c7215ab7f522c19c9aa44e73a7767 129 Gene3D G3DSA:1.10.287.1080 50 97 7.6E-5 T 06-07-2017 LK06_RS24005 3c60e031bd90e69329de6253de269728 308 SUPERFAMILY SSF51730 35 304 1.06E-68 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like LK06_RS24005 3c60e031bd90e69329de6253de269728 308 Pfam PF01619 Proline dehydrogenase 45 300 3.3E-32 T 06-07-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 LK06_RS24005 3c60e031bd90e69329de6253de269728 308 Gene3D G3DSA:3.20.20.220 35 303 3.7E-68 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like LK06_RS24005 3c60e031bd90e69329de6253de269728 308 PIRSF PIRSF000196 1 308 2.3E-113 T 06-07-2017 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 LK06_RS09320 450e7b2d17cc0fa9b5b51191009d0dcd 248 Gene3D G3DSA:2.40.50.140 1 86 2.8E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS09320 450e7b2d17cc0fa9b5b51191009d0dcd 248 Pfam PF11967 Recombination protein O N terminal 1 85 2.2E-28 T 06-07-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal LK06_RS09320 450e7b2d17cc0fa9b5b51191009d0dcd 248 Pfam PF02565 Recombination protein O C terminal 91 244 5.7E-32 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 LK06_RS09320 450e7b2d17cc0fa9b5b51191009d0dcd 248 SUPERFAMILY SSF57863 88 238 1.18E-38 T 06-07-2017 LK06_RS09320 450e7b2d17cc0fa9b5b51191009d0dcd 248 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 245 2.5E-36 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 LK06_RS09320 450e7b2d17cc0fa9b5b51191009d0dcd 248 SUPERFAMILY SSF50249 1 84 9.42E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS09320 450e7b2d17cc0fa9b5b51191009d0dcd 248 Hamap MF_00201 DNA repair protein RecO [recO]. 2 248 25.923 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 LK06_RS04135 7dd6c2eb7e52567be2ed451bd9cce0ee 189 Gene3D G3DSA:3.40.50.2020 17 180 9.9E-51 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS04135 7dd6c2eb7e52567be2ed451bd9cce0ee 189 Pfam PF00156 Phosphoribosyl transferase domain 15 155 7.2E-21 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 LK06_RS04135 7dd6c2eb7e52567be2ed451bd9cce0ee 189 SUPERFAMILY SSF53271 14 181 1.1E-41 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS04135 7dd6c2eb7e52567be2ed451bd9cce0ee 189 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 12 185 37.036 T 06-07-2017 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 LK06_RS25985 adb386ca5bd387dd467cdd8169245ce3 334 Gene3D G3DSA:3.40.50.300 54 257 4.1E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25985 adb386ca5bd387dd467cdd8169245ce3 334 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 16 321 4.9E-112 T 06-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS25985 adb386ca5bd387dd467cdd8169245ce3 334 Pfam PF03308 ArgK protein 22 292 3.4E-110 T 06-07-2017 LK06_RS25985 adb386ca5bd387dd467cdd8169245ce3 334 Gene3D G3DSA:1.20.5.170 4 53 8.5E-22 T 06-07-2017 LK06_RS25985 adb386ca5bd387dd467cdd8169245ce3 334 SUPERFAMILY SSF52540 3 324 8.66E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 Gene3D G3DSA:3.30.200.20 4 94 5.2E-30 T 06-07-2017 LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 SMART SM00220 11 277 4.3E-70 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 SMART SM00740 580 645 1.2E-7 T 06-07-2017 IPR005543 PASTA domain LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 SMART SM00740 443 508 5.1E-18 T 06-07-2017 IPR005543 PASTA domain LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 SMART SM00740 509 577 5.6E-11 T 06-07-2017 IPR005543 PASTA domain LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 SMART SM00740 376 442 2.4E-11 T 06-07-2017 IPR005543 PASTA domain LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 SUPERFAMILY SSF56112 7 274 1.48E-80 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 Pfam PF00069 Protein kinase domain 11 265 4.1E-52 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 Pfam PF03793 PASTA domain 584 643 1.1E-9 T 06-07-2017 IPR005543 PASTA domain LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 Pfam PF03793 PASTA domain 447 508 4.5E-15 T 06-07-2017 IPR005543 PASTA domain LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 Pfam PF03793 PASTA domain 380 442 4.2E-13 T 06-07-2017 IPR005543 PASTA domain LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 Pfam PF03793 PASTA domain 513 575 2.3E-11 T 06-07-2017 IPR005543 PASTA domain LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS15590 742d1c1d41d6864d6fa75e993cb4617b 666 Gene3D G3DSA:1.10.510.10 98 274 2.8E-51 T 06-07-2017 LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 SMART SM01383 42 119 6.8E-40 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 Gene3D G3DSA:2.40.50.140 1 115 2.3E-51 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 SMART SM01382 125 253 9.8E-88 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 SUPERFAMILY SSF50104 127 271 7.82E-56 T 06-07-2017 IPR008991 Translation protein SH3-like domain LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.866 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 2.3E-54 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 3.2E-127 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 Gene3D G3DSA:2.30.30.30 120 196 7.9E-29 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 06-07-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 Gene3D G3DSA:4.10.950.10 197 273 9.9E-33 T 06-07-2017 IPR014726 Ribosomal protein L2, domain 3 LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 SUPERFAMILY SSF50249 3 126 5.48E-49 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 3.3E-32 T 06-07-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12300 4b64acef8de4269e1b962cd54bb29a69 278 PIRSF PIRSF002158 4 275 1.3E-92 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS25770 bf4c56c2b43e7f9f96161ba53848b192 157 Pfam PF13686 DsrE/DsrF/DrsH-like family 8 153 7.3E-30 T 06-07-2017 IPR032836 DsrE/DsrF/DrsH-like family LK06_RS25770 bf4c56c2b43e7f9f96161ba53848b192 157 SUPERFAMILY SSF75169 9 54 7.65E-15 T 06-07-2017 IPR027396 DsrEFH-like LK06_RS25770 bf4c56c2b43e7f9f96161ba53848b192 157 SUPERFAMILY SSF75169 99 147 7.65E-15 T 06-07-2017 IPR027396 DsrEFH-like LK06_RS25770 bf4c56c2b43e7f9f96161ba53848b192 157 Gene3D G3DSA:3.40.1260.10 6 155 1.6E-35 T 06-07-2017 IPR027396 DsrEFH-like LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 Pfam PF06628 Catalase-related immune-responsive 423 484 3.8E-21 T 06-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 Gene3D G3DSA:2.40.180.10 5 360 1.7E-180 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 ProSitePatterns PS00438 Catalase proximal active site signature. 46 62 - T 06-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 SUPERFAMILY SSF56634 7 485 1.96E-205 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 SMART SM01060 10 397 1.6E-277 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 PRINTS PR00067 Catalase signature 107 124 5.0E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 PRINTS PR00067 Catalase signature 126 144 5.0E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 PRINTS PR00067 Catalase signature 323 349 5.0E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 PRINTS PR00067 Catalase signature 23 46 5.0E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 PRINTS PR00067 Catalase signature 86 104 5.0E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 PRINTS PR00067 Catalase signature 291 318 5.0E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 Pfam PF00199 Catalase 10 394 2.0E-187 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 PIRSF PIRSF038928 2 490 5.3E-219 T 06-07-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS27370 838ab82c7bb2a69ee0165aa20c7cb387 490 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 336 344 - T 06-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 LK06_RS12360 bfeab5201cea6d8840e076d2dde7ce3b 561 SMART SM00530 137 192 3.4E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS12360 bfeab5201cea6d8840e076d2dde7ce3b 561 Gene3D G3DSA:1.10.260.40 133 178 1.0E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS12360 bfeab5201cea6d8840e076d2dde7ce3b 561 SUPERFAMILY SSF47413 131 202 1.18E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS12360 bfeab5201cea6d8840e076d2dde7ce3b 561 Pfam PF13560 Helix-turn-helix domain 133 193 1.6E-8 T 06-07-2017 LK06_RS12360 bfeab5201cea6d8840e076d2dde7ce3b 561 Gene3D G3DSA:1.25.40.10 327 509 5.4E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15115 469c3e6b9b712e49af25a359d7543547 172 Pfam PF08281 Sigma-70, region 4 98 150 4.8E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15115 469c3e6b9b712e49af25a359d7543547 172 SUPERFAMILY SSF88946 3 94 5.49E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15115 469c3e6b9b712e49af25a359d7543547 172 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 31 62 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15115 469c3e6b9b712e49af25a359d7543547 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 153 1.3E-21 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15115 469c3e6b9b712e49af25a359d7543547 172 SUPERFAMILY SSF88659 97 154 1.01E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15115 469c3e6b9b712e49af25a359d7543547 172 Pfam PF04542 Sigma-70 region 2 10 76 6.0E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15115 469c3e6b9b712e49af25a359d7543547 172 Gene3D G3DSA:1.10.10.10 99 155 3.9E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15115 469c3e6b9b712e49af25a359d7543547 172 Gene3D G3DSA:1.10.1740.10 3 96 1.4E-21 T 06-07-2017 LK06_RS15115 469c3e6b9b712e49af25a359d7543547 172 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 2 156 5.3E-48 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 LK06_RS20870 6fab25dda3b5d1239488f50005290555 374 SUPERFAMILY SSF55073 184 317 1.73E-29 T 06-07-2017 IPR029787 Nucleotide cyclase LK06_RS20870 6fab25dda3b5d1239488f50005290555 374 SMART SM00044 71 324 5.7E-4 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 LK06_RS20870 6fab25dda3b5d1239488f50005290555 374 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 186 309 6.8E-13 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 LK06_RS20870 6fab25dda3b5d1239488f50005290555 374 Pfam PF16701 Adenylate cyclase regulatory domain 30 157 1.2E-8 T 06-07-2017 IPR032026 Adenylate cyclase regulatory domain LK06_RS20870 6fab25dda3b5d1239488f50005290555 374 Gene3D G3DSA:3.30.70.1230 185 363 6.4E-19 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 LK06_RS06080 10a7eaac9576f1132b1a5e408e3c5282 349 Gene3D G3DSA:3.90.180.10 1 171 3.2E-39 T 06-07-2017 IPR011032 GroES-like LK06_RS06080 10a7eaac9576f1132b1a5e408e3c5282 349 Gene3D G3DSA:3.40.50.720 172 292 8.1E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06080 10a7eaac9576f1132b1a5e408e3c5282 349 SUPERFAMILY SSF51735 148 314 9.41E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06080 10a7eaac9576f1132b1a5e408e3c5282 349 SUPERFAMILY SSF50129 1 169 1.67E-48 T 06-07-2017 IPR011032 GroES-like LK06_RS06080 10a7eaac9576f1132b1a5e408e3c5282 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 128 1.2E-25 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS06080 10a7eaac9576f1132b1a5e408e3c5282 349 Pfam PF00107 Zinc-binding dehydrogenase 180 307 1.1E-21 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS25270 c3938ba13cb4c7c071f32e62d4bf5562 810 Gene3D G3DSA:3.40.50.300 13 220 6.9E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25270 c3938ba13cb4c7c071f32e62d4bf5562 810 SMART SM00382 28 205 1.1E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS25270 c3938ba13cb4c7c071f32e62d4bf5562 810 Pfam PF00005 ABC transporter 20 156 2.3E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS25270 c3938ba13cb4c7c071f32e62d4bf5562 810 SUPERFAMILY SSF52540 7 218 2.34E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07485 b206d1cd96341b66480a12912023858c 342 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 06-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 Pfam PF00365 Phosphofructokinase 2 298 2.1E-102 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 2.5E-70 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 2.5E-70 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 2.5E-70 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.5E-70 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 2.5E-70 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.5E-70 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.5E-70 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.5E-70 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 2.5E-70 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 PIRSF PIRSF000532 1 339 5.0E-121 T 06-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 322 3.8E-150 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 Gene3D G3DSA:3.40.50.450 1 211 3.0E-74 T 06-07-2017 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 SUPERFAMILY SSF53784 1 334 1.57E-122 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS07485 b206d1cd96341b66480a12912023858c 342 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 342 43.082 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 LK06_RS07665 a6ac1ad700a2636863e86d4ac5968185 324 PRINTS PR00990 Ribokinase signature 42 61 4.0E-5 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS07665 a6ac1ad700a2636863e86d4ac5968185 324 PRINTS PR00990 Ribokinase signature 220 231 4.0E-5 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS07665 a6ac1ad700a2636863e86d4ac5968185 324 PRINTS PR00990 Ribokinase signature 184 199 4.0E-5 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS07665 a6ac1ad700a2636863e86d4ac5968185 324 Gene3D G3DSA:3.40.1190.20 2 308 3.0E-46 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS07665 a6ac1ad700a2636863e86d4ac5968185 324 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 LK06_RS07665 a6ac1ad700a2636863e86d4ac5968185 324 Pfam PF00294 pfkB family carbohydrate kinase 32 295 6.4E-38 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB LK06_RS07665 a6ac1ad700a2636863e86d4ac5968185 324 SUPERFAMILY SSF53613 2 296 3.43E-53 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 Pfam PF00106 short chain dehydrogenase 40 222 1.2E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 110 121 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 183 202 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 171 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 170 198 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 39 218 4.9E-5 T 06-07-2017 LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 Gene3D G3DSA:3.40.50.720 38 257 4.4E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 173 9.8E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 40 57 9.8E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 221 9.8E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 202 9.8E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 110 121 9.8E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01060 f78ee23ba1bb633c48a7de51f5214542 284 SUPERFAMILY SSF51735 37 282 1.06E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 SUPERFAMILY SSF100950 76 241 1.09E-23 T 06-07-2017 LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.5E-7 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.5E-7 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 Gene3D G3DSA:1.10.10.10 1 57 3.9E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.6E-15 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 SMART SM00420 6 58 5.1E-13 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 SMART SM01134 72 240 2.1E-57 T 06-07-2017 LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 SUPERFAMILY SSF46785 4 65 7.79E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 Pfam PF00455 DeoR C terminal sensor domain 75 239 4.8E-48 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain LK06_RS30015 ae882f91203187eb3ba7a313f3fd8bd7 259 Gene3D G3DSA:3.40.50.1360 76 223 3.7E-12 T 06-07-2017 LK06_RS24305 63982feb63aa251b3b878599ce9ebfd2 130 Pfam PF01638 HxlR-like helix-turn-helix 29 114 6.2E-24 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type LK06_RS24305 63982feb63aa251b3b878599ce9ebfd2 130 SUPERFAMILY SSF46785 13 120 8.19E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS24305 63982feb63aa251b3b878599ce9ebfd2 130 Gene3D G3DSA:1.10.10.10 11 127 1.8E-40 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25940 741b48988e7b5770da9b458aabe16438 517 Pfam PF09660 Protein of unknown function (DUF2397) 9 492 5.7E-142 T 06-07-2017 IPR013493 Conserved hypothetical protein CHP02677 LK06_RS25940 741b48988e7b5770da9b458aabe16438 517 TIGRFAM TIGR02677 TIGR02677: TIGR02677 family protein 7 501 1.8E-179 T 06-07-2017 IPR013493 Conserved hypothetical protein CHP02677 LK06_RS17970 734044f43c6456d111cd95aa0decd966 262 Gene3D G3DSA:1.10.10.10 13 84 1.1E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17970 734044f43c6456d111cd95aa0decd966 262 SMART SM00866 115 254 2.6E-23 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS17970 734044f43c6456d111cd95aa0decd966 262 SUPERFAMILY SSF64288 71 259 2.83E-32 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS17970 734044f43c6456d111cd95aa0decd966 262 Gene3D G3DSA:3.40.1410.10 85 257 5.1E-59 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS17970 734044f43c6456d111cd95aa0decd966 262 SMART SM00345 24 83 5.9E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17970 734044f43c6456d111cd95aa0decd966 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 2.9E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17970 734044f43c6456d111cd95aa0decd966 262 SUPERFAMILY SSF46785 13 95 6.34E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17970 734044f43c6456d111cd95aa0decd966 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 1.4E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17970 734044f43c6456d111cd95aa0decd966 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 1.4E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17970 734044f43c6456d111cd95aa0decd966 262 Pfam PF07702 UTRA domain 116 253 3.7E-28 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 Gene3D G3DSA:3.40.50.1100 43 147 1.0E-39 T 06-07-2017 LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 458 3.9E-217 T 06-07-2017 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 Gene3D G3DSA:3.40.50.1100 153 313 1.5E-71 T 06-07-2017 LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 Gene3D G3DSA:3.40.50.1100 2 42 1.5E-71 T 06-07-2017 LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 SMART SM00116 340 396 0.032 T 06-07-2017 IPR000644 CBS domain LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 SMART SM00116 413 458 21.0 T 06-07-2017 IPR000644 CBS domain LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 SUPERFAMILY SSF54631 339 459 1.77E-15 T 06-07-2017 LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 296 1.8E-72 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 Gene3D G3DSA:3.10.580.10 339 459 3.1E-20 T 06-07-2017 LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 Pfam PF00571 CBS domain 340 396 1.6E-5 T 06-07-2017 IPR000644 CBS domain LK06_RS20035 ab092754d798d6ee244bb6a0326ade39 463 SUPERFAMILY SSF53686 3 317 1.44E-99 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS15305 092770c8b904e2331bd42431592dbd00 699 SUPERFAMILY SSF81606 343 555 9.15E-8 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15305 092770c8b904e2331bd42431592dbd00 699 Pfam PF13581 Histidine kinase-like ATPase domain 585 689 6.7E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS15305 092770c8b904e2331bd42431592dbd00 699 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 356 557 3.1E-49 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15305 092770c8b904e2331bd42431592dbd00 699 SMART SM00065 160 309 0.0098 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS15305 092770c8b904e2331bd42431592dbd00 699 SUPERFAMILY SSF55785 15 124 1.11E-6 T 06-07-2017 IPR000014 PAS domain LK06_RS15305 092770c8b904e2331bd42431592dbd00 699 SMART SM00331 330 557 2.9E-28 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15305 092770c8b904e2331bd42431592dbd00 699 SUPERFAMILY SSF55781 161 311 2.14E-16 T 06-07-2017 IPR029016 GAF domain-like LK06_RS15305 092770c8b904e2331bd42431592dbd00 699 Gene3D G3DSA:3.30.450.40 144 302 1.1E-15 T 06-07-2017 IPR029016 GAF domain-like LK06_RS15305 092770c8b904e2331bd42431592dbd00 699 Gene3D G3DSA:3.30.450.20 11 123 2.2E-10 T 06-07-2017 LK06_RS15305 092770c8b904e2331bd42431592dbd00 699 Pfam PF13185 GAF domain 161 299 2.1E-12 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 Gene3D G3DSA:3.30.160.40 223 307 3.4E-18 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 PIRSF PIRSF001438 2 311 1.0E-95 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 300 33.25 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 300 1.3E-97 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 229 298 1.3E-12 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 SUPERFAMILY SSF53850 6 219 3.91E-64 T 06-07-2017 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 Gene3D G3DSA:3.40.190.10 6 112 7.7E-34 T 06-07-2017 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 214 5.0E-61 T 06-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 SUPERFAMILY SSF54782 223 309 4.58E-19 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 233 249 - T 06-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 Gene3D G3DSA:3.40.190.10 113 201 1.6E-31 T 06-07-2017 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 6.9E-24 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 PRINTS PR00151 Porphobilinogen deaminase signature 126 143 6.9E-24 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 PRINTS PR00151 Porphobilinogen deaminase signature 232 249 6.9E-24 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 6.9E-24 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31015 d47917d3ff3c7da1d757c428386aeb3a 311 PRINTS PR00151 Porphobilinogen deaminase signature 145 162 6.9E-24 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS31545 97a46ce64baa76c8fa9282e9eeb0208f 191 SUPERFAMILY SSF50475 64 188 9.81E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS31545 97a46ce64baa76c8fa9282e9eeb0208f 191 Gene3D G3DSA:2.30.110.10 64 189 1.7E-29 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS31545 97a46ce64baa76c8fa9282e9eeb0208f 191 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 65 186 1.4E-21 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 SMART SM01008 39 145 1.7E-44 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 SUPERFAMILY SSF56003 146 762 3.66E-119 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 Gene3D G3DSA:3.30.365.10 134 186 1.5E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 Gene3D G3DSA:3.30.365.10 289 363 1.5E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 167 708 4.1E-106 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 Gene3D G3DSA:3.30.365.10 187 287 2.1E-17 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 Gene3D G3DSA:3.30.365.10 366 469 1.5E-39 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 Gene3D G3DSA:3.30.365.10 637 762 1.5E-39 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 40 144 1.5E-29 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 SUPERFAMILY SSF54665 23 159 9.29E-40 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 Gene3D G3DSA:3.90.1170.50 23 133 7.3E-41 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LK06_RS11395 4fed572e7a6d9aedac641df5fed3a952 769 Gene3D G3DSA:3.30.365.10 477 636 5.3E-23 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LK06_RS29280 0314376f9447ba306acf94586ab5a249 129 Pfam PF13466 STAS domain 23 103 9.4E-14 T 06-07-2017 IPR002645 STAS domain LK06_RS29280 0314376f9447ba306acf94586ab5a249 129 SUPERFAMILY SSF52091 13 117 3.14E-20 T 06-07-2017 IPR002645 STAS domain LK06_RS29280 0314376f9447ba306acf94586ab5a249 129 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 10 112 1.3E-19 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 LK06_RS29280 0314376f9447ba306acf94586ab5a249 129 Gene3D G3DSA:3.30.750.24 11 120 2.7E-26 T 06-07-2017 IPR002645 STAS domain LK06_RS22985 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 337 4.2E-33 T 06-07-2017 IPR000477 Reverse transcriptase domain LK06_RS22985 87da00ed7514833d10ddeefb0064afaa 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 425 6.9E-103 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase LK06_RS22985 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF08388 Group II intron, maturase-specific domain 361 437 3.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS22985 87da00ed7514833d10ddeefb0064afaa 478 SUPERFAMILY SSF56672 2 437 1.06E-48 T 06-07-2017 LK06_RS32340 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 337 4.2E-33 T 06-07-2017 IPR000477 Reverse transcriptase domain LK06_RS32340 87da00ed7514833d10ddeefb0064afaa 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 425 6.9E-103 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase LK06_RS32340 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF08388 Group II intron, maturase-specific domain 361 437 3.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS32340 87da00ed7514833d10ddeefb0064afaa 478 SUPERFAMILY SSF56672 2 437 1.06E-48 T 06-07-2017 LK06_RS03430 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 337 4.2E-33 T 06-07-2017 IPR000477 Reverse transcriptase domain LK06_RS03430 87da00ed7514833d10ddeefb0064afaa 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 425 6.9E-103 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase LK06_RS03430 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF08388 Group II intron, maturase-specific domain 361 437 3.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS03430 87da00ed7514833d10ddeefb0064afaa 478 SUPERFAMILY SSF56672 2 437 1.06E-48 T 06-07-2017 LK06_RS08370 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 337 4.2E-33 T 06-07-2017 IPR000477 Reverse transcriptase domain LK06_RS08370 87da00ed7514833d10ddeefb0064afaa 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 425 6.9E-103 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase LK06_RS08370 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF08388 Group II intron, maturase-specific domain 361 437 3.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS08370 87da00ed7514833d10ddeefb0064afaa 478 SUPERFAMILY SSF56672 2 437 1.06E-48 T 06-07-2017 LK06_RS22905 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 337 4.2E-33 T 06-07-2017 IPR000477 Reverse transcriptase domain LK06_RS22905 87da00ed7514833d10ddeefb0064afaa 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 425 6.9E-103 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase LK06_RS22905 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF08388 Group II intron, maturase-specific domain 361 437 3.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS22905 87da00ed7514833d10ddeefb0064afaa 478 SUPERFAMILY SSF56672 2 437 1.06E-48 T 06-07-2017 LK06_RS19195 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 337 4.2E-33 T 06-07-2017 IPR000477 Reverse transcriptase domain LK06_RS19195 87da00ed7514833d10ddeefb0064afaa 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 425 6.9E-103 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase LK06_RS19195 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF08388 Group II intron, maturase-specific domain 361 437 3.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS19195 87da00ed7514833d10ddeefb0064afaa 478 SUPERFAMILY SSF56672 2 437 1.06E-48 T 06-07-2017 LK06_RS00725 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 337 4.2E-33 T 06-07-2017 IPR000477 Reverse transcriptase domain LK06_RS00725 87da00ed7514833d10ddeefb0064afaa 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 425 6.9E-103 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase LK06_RS00725 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF08388 Group II intron, maturase-specific domain 361 437 3.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS00725 87da00ed7514833d10ddeefb0064afaa 478 SUPERFAMILY SSF56672 2 437 1.06E-48 T 06-07-2017 LK06_RS14660 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 337 4.2E-33 T 06-07-2017 IPR000477 Reverse transcriptase domain LK06_RS14660 87da00ed7514833d10ddeefb0064afaa 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 425 6.9E-103 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase LK06_RS14660 87da00ed7514833d10ddeefb0064afaa 478 Pfam PF08388 Group II intron, maturase-specific domain 361 437 3.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS14660 87da00ed7514833d10ddeefb0064afaa 478 SUPERFAMILY SSF56672 2 437 1.06E-48 T 06-07-2017 LK06_RS32320 332690e47640c11dd8e8ef467c71ae71 244 Gene3D G3DSA:1.10.357.10 18 188 1.5E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS32320 332690e47640c11dd8e8ef467c71ae71 244 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 1.3E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS32320 332690e47640c11dd8e8ef467c71ae71 244 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 4.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS32320 332690e47640c11dd8e8ef467c71ae71 244 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 4.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS32320 332690e47640c11dd8e8ef467c71ae71 244 SUPERFAMILY SSF46689 18 82 2.98E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS32320 332690e47640c11dd8e8ef467c71ae71 244 SUPERFAMILY SSF48498 92 178 1.0E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS20885 755f761d526c6a7c31bb45927bed3552 380 SMART SM00267 179 349 5.9E-45 T 06-07-2017 IPR000160 GGDEF domain LK06_RS20885 755f761d526c6a7c31bb45927bed3552 380 SUPERFAMILY SSF55781 28 180 1.57E-9 T 06-07-2017 IPR029016 GAF domain-like LK06_RS20885 755f761d526c6a7c31bb45927bed3552 380 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 188 342 5.4E-26 T 06-07-2017 IPR000160 GGDEF domain LK06_RS20885 755f761d526c6a7c31bb45927bed3552 380 Gene3D G3DSA:3.30.70.270 191 344 1.1E-34 T 06-07-2017 LK06_RS20885 755f761d526c6a7c31bb45927bed3552 380 Pfam PF00990 Diguanylate cyclase, GGDEF domain 190 340 5.1E-28 T 06-07-2017 IPR000160 GGDEF domain LK06_RS20885 755f761d526c6a7c31bb45927bed3552 380 Gene3D G3DSA:3.30.450.40 16 184 1.0E-10 T 06-07-2017 IPR029016 GAF domain-like LK06_RS20885 755f761d526c6a7c31bb45927bed3552 380 SUPERFAMILY SSF55073 195 342 6.51E-30 T 06-07-2017 IPR029787 Nucleotide cyclase LK06_RS06745 5d4ff130aaaa3dc139c879200735c624 375 SUPERFAMILY SSF144083 311 372 2.35E-19 T 06-07-2017 LK06_RS06745 5d4ff130aaaa3dc139c879200735c624 375 Gene3D G3DSA:1.20.58.340 299 375 3.0E-26 T 06-07-2017 LK06_RS06745 5d4ff130aaaa3dc139c879200735c624 375 SUPERFAMILY SSF143865 44 307 3.53E-62 T 06-07-2017 LK06_RS06745 5d4ff130aaaa3dc139c879200735c624 375 Pfam PF01544 CorA-like Mg2+ transporter protein 76 366 2.1E-59 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 LK06_RS06745 5d4ff130aaaa3dc139c879200735c624 375 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 76 375 2.3E-60 T 06-07-2017 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 LK06_RS06745 5d4ff130aaaa3dc139c879200735c624 375 Gene3D G3DSA:1.20.58.340 185 297 6.2E-36 T 06-07-2017 LK06_RS06745 5d4ff130aaaa3dc139c879200735c624 375 Gene3D G3DSA:3.30.460.20 29 184 1.4E-40 T 06-07-2017 LK06_RS02640 16519d3629ba920898fb8bb2e6bc4e2e 617 SUPERFAMILY SSF52777 168 375 1.22E-30 T 06-07-2017 LK06_RS02640 16519d3629ba920898fb8bb2e6bc4e2e 617 Gene3D G3DSA:3.90.820.10 104 162 2.9E-26 T 06-07-2017 LK06_RS02640 16519d3629ba920898fb8bb2e6bc4e2e 617 Pfam PF03621 MbtH-like protein 95 145 2.9E-23 T 06-07-2017 IPR005153 MbtH-like protein LK06_RS02640 16519d3629ba920898fb8bb2e6bc4e2e 617 SUPERFAMILY SSF52777 365 613 2.0E-36 T 06-07-2017 LK06_RS02640 16519d3629ba920898fb8bb2e6bc4e2e 617 SMART SM00923 96 146 4.4E-26 T 06-07-2017 IPR005153 MbtH-like protein LK06_RS02640 16519d3629ba920898fb8bb2e6bc4e2e 617 SUPERFAMILY SSF160582 95 161 9.68E-26 T 06-07-2017 LK06_RS02640 16519d3629ba920898fb8bb2e6bc4e2e 617 Pfam PF00668 Condensation domain 204 473 1.6E-45 T 06-07-2017 IPR001242 Condensation domain LK06_RS13435 011fe31e5e4be842949b46bca1063bef 90 SUPERFAMILY SSF52833 10 89 4.0E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS13435 011fe31e5e4be842949b46bca1063bef 90 Gene3D G3DSA:3.40.30.10 16 89 9.4E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS13435 011fe31e5e4be842949b46bca1063bef 90 Pfam PF05768 Glutaredoxin-like domain (DUF836) 16 88 9.2E-19 T 06-07-2017 IPR008554 Glutaredoxin-like LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 271 347 5.0E-23 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 23 254 6.6E-110 T 06-07-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 364 160.356 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 Gene3D G3DSA:3.40.50.300 39 84 8.6E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 SMART SM00382 70 201 1.7E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 272 345 2.8E-29 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 Gene3D G3DSA:1.10.8.60 209 273 8.6E-33 T 06-07-2017 LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 Gene3D G3DSA:1.10.10.10 276 346 1.3E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 SUPERFAMILY SSF52540 39 270 1.04E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 Gene3D G3DSA:3.40.50.300 85 208 4.8E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 43 345 5.5E-136 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 LK06_RS04280 afd57a4eeab9941b6362414815e43464 364 SUPERFAMILY SSF46785 276 349 1.48E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 SUPERFAMILY SSF54909 69 146 1.47E-14 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 Gene3D G3DSA:3.30.70.920 61 139 7.1E-19 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 SUPERFAMILY SSF46785 8 68 3.75E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 SMART SM00344 8 115 5.6E-38 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 3.1E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 3.1E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 3.1E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 ProSitePatterns PS00519 AsnC-type HTH domain signature. 26 52 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 Gene3D G3DSA:1.10.10.10 7 59 4.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 Pfam PF01037 Lrp/AsnC ligand binding domain 74 144 8.1E-15 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS02265 9f3cee2cd4a74937f940334d102585b3 161 Pfam PF13404 AsnC-type helix-turn-helix domain 9 49 2.1E-17 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS28205 9654ca1a2dfe2c591b69eaf6375aecff 203 Gene3D G3DSA:3.30.70.900 8 62 5.8E-5 T 06-07-2017 LK06_RS28205 9654ca1a2dfe2c591b69eaf6375aecff 203 SUPERFAMILY SSF54909 1 92 3.35E-7 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 SUPERFAMILY SSF55979 1 118 5.76E-20 T 06-07-2017 LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 SUPERFAMILY SSF55979 256 361 7.85E-14 T 06-07-2017 LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 247 2.0E-22 T 06-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 SMART SM00480 17 367 1.6E-67 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 Gene3D G3DSA:3.10.150.10 259 376 5.4E-20 T 06-07-2017 LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 SUPERFAMILY SSF55979 126 251 9.42E-16 T 06-07-2017 LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 Gene3D G3DSA:3.10.150.10 1 120 3.3E-23 T 06-07-2017 LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 Gene3D G3DSA:3.10.150.10 124 252 7.1E-25 T 06-07-2017 LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 1.0E-63 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 258 361 4.8E-15 T 06-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS18110 d95caf2e5155e8b426df72da3c9ad68d 379 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 118 2.4E-26 T 06-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 SUPERFAMILY SSF51905 157 323 7.86E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 Pfam PF04324 BFD-like [2Fe-2S] binding domain 431 480 6.0E-12 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PRINTS PR00397 Sirohaem Fe-binding site signature 698 716 4.4E-6 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PRINTS PR00397 Sirohaem Fe-binding site signature 655 673 4.4E-6 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PIRSF PIRSF037149 9 866 0.0 T 06-07-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 304 5.2E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 182 9.9E-8 T 06-07-2017 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 9.9E-8 T 06-07-2017 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 245 259 9.9E-8 T 06-07-2017 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 9.9E-8 T 06-07-2017 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 651 776 3.1E-18 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 15 820 0.0 T 06-07-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 698 714 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 SUPERFAMILY SSF56014 652 826 1.06E-49 T 06-07-2017 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 Gene3D G3DSA:3.30.413.10 651 787 1.1E-33 T 06-07-2017 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 SUPERFAMILY SSF51905 14 198 1.14E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 1.8E-8 T 06-07-2017 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 1.8E-8 T 06-07-2017 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 1.8E-8 T 06-07-2017 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 260 1.8E-8 T 06-07-2017 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 Gene3D G3DSA:3.50.50.60 121 320 9.7E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 579 640 1.3E-9 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 SUPERFAMILY SSF55124 532 660 1.21E-21 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS09230 f8dde40a6bd0f4f3bb82791671f37094 873 Gene3D G3DSA:3.50.50.60 13 120 9.1E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS21425 355d674bc7b24fa677818fe65bd15f15 698 Pfam PF13581 Histidine kinase-like ATPase domain 593 679 1.3E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21425 355d674bc7b24fa677818fe65bd15f15 698 SUPERFAMILY SSF55781 276 340 3.04E-6 T 06-07-2017 IPR029016 GAF domain-like LK06_RS21425 355d674bc7b24fa677818fe65bd15f15 698 SMART SM00331 354 571 5.5E-37 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS21425 355d674bc7b24fa677818fe65bd15f15 698 SUPERFAMILY SSF55874 612 694 3.95E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21425 355d674bc7b24fa677818fe65bd15f15 698 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 380 572 4.7E-54 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS21425 355d674bc7b24fa677818fe65bd15f15 698 SUPERFAMILY SSF81606 368 572 3.66E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS21425 355d674bc7b24fa677818fe65bd15f15 698 Gene3D G3DSA:3.30.450.40 138 330 3.8E-22 T 06-07-2017 IPR029016 GAF domain-like LK06_RS30995 e9e23912099a77966a446cf51d2b2e4b 274 SUPERFAMILY SSF54593 159 270 2.48E-8 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30995 e9e23912099a77966a446cf51d2b2e4b 274 SUPERFAMILY SSF54593 32 153 1.61E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30995 e9e23912099a77966a446cf51d2b2e4b 274 Gene3D G3DSA:3.10.180.10 31 141 1.9E-25 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30995 e9e23912099a77966a446cf51d2b2e4b 274 Gene3D G3DSA:3.10.180.10 156 270 2.1E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS21085 4f9dace97b58d44d03e31135a205e886 336 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 9 308 5.6E-115 T 06-07-2017 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA LK06_RS21085 4f9dace97b58d44d03e31135a205e886 336 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 288 6.0E-48 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS21085 4f9dace97b58d44d03e31135a205e886 336 Gene3D G3DSA:3.40.50.1100 138 304 8.5E-46 T 06-07-2017 LK06_RS21085 4f9dace97b58d44d03e31135a205e886 336 Gene3D G3DSA:3.40.50.1100 35 137 5.7E-21 T 06-07-2017 LK06_RS21085 4f9dace97b58d44d03e31135a205e886 336 SUPERFAMILY SSF53686 19 311 3.93E-67 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS27810 0cb542e54b0ee54300d56116cd145e4f 522 Gene3D G3DSA:2.60.120.260 336 519 1.8E-10 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS27810 0cb542e54b0ee54300d56116cd145e4f 522 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 317 507 1.4E-13 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 LK06_RS27810 0cb542e54b0ee54300d56116cd145e4f 522 Gene3D G3DSA:3.40.50.1820 39 181 6.1E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27810 0cb542e54b0ee54300d56116cd145e4f 522 Gene3D G3DSA:3.40.50.1820 233 335 6.1E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27810 0cb542e54b0ee54300d56116cd145e4f 522 SMART SM00939 305 515 3.4E-22 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 LK06_RS27810 0cb542e54b0ee54300d56116cd145e4f 522 SUPERFAMILY SSF49785 376 518 2.98E-12 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS27810 0cb542e54b0ee54300d56116cd145e4f 522 SUPERFAMILY SSF49785 306 344 2.98E-12 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS27810 0cb542e54b0ee54300d56116cd145e4f 522 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 49 359 8.2E-22 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 LK06_RS27810 0cb542e54b0ee54300d56116cd145e4f 522 SUPERFAMILY SSF53474 42 341 9.87E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27810 0cb542e54b0ee54300d56116cd145e4f 522 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 48 286 7.1E-36 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 SUPERFAMILY SSF55874 315 403 1.51E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 SUPERFAMILY SSF55874 432 506 1.51E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 Pfam PF00512 His Kinase A (phospho-acceptor) domain 261 325 2.9E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 Gene3D G3DSA:1.10.287.130 252 312 3.1E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 SUPERFAMILY SSF158472 199 249 1.22E-8 T 06-07-2017 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 SMART SM00388 259 326 9.2E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 485 9.3E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 504 9.3E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 461 9.3E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 447 9.3E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 Gene3D G3DSA:3.30.565.10 313 506 2.0E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 Pfam PF00672 HAMP domain 186 247 1.1E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 SUPERFAMILY SSF47384 244 325 3.14E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 SMART SM00304 199 251 3.6E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 SMART SM00387 368 507 3.8E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20645 5728a8f0baa4a6c80595c6fba53fe7d6 512 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 369 505 6.3E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS26245 f9bf86e4eea2ef9097fb3990d226372f 61 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 61 2.5E-16 T 06-07-2017 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 LK06_RS26245 f9bf86e4eea2ef9097fb3990d226372f 61 Gene3D G3DSA:3.30.429.20 1 60 6.4E-21 T 06-07-2017 LK06_RS26245 f9bf86e4eea2ef9097fb3990d226372f 61 SUPERFAMILY SSF55331 2 60 3.38E-16 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily LK06_RS26245 f9bf86e4eea2ef9097fb3990d226372f 61 Pfam PF01361 Tautomerase enzyme 2 57 9.1E-15 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 LK06_RS15400 bb490f1ab97d8dc74982636e9722b51d 536 SUPERFAMILY SSF56112 424 491 7.28E-74 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS15400 bb490f1ab97d8dc74982636e9722b51d 536 SUPERFAMILY SSF56112 36 302 7.28E-74 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS15400 bb490f1ab97d8dc74982636e9722b51d 536 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 161 173 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS15400 bb490f1ab97d8dc74982636e9722b51d 536 Pfam PF00069 Protein kinase domain 38 293 2.0E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS15400 bb490f1ab97d8dc74982636e9722b51d 536 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 44 67 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS15400 bb490f1ab97d8dc74982636e9722b51d 536 Gene3D G3DSA:1.10.510.10 431 482 1.2E-49 T 06-07-2017 LK06_RS15400 bb490f1ab97d8dc74982636e9722b51d 536 Gene3D G3DSA:1.10.510.10 128 301 1.2E-49 T 06-07-2017 LK06_RS15400 bb490f1ab97d8dc74982636e9722b51d 536 SMART SM00220 38 300 2.0E-56 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS15400 bb490f1ab97d8dc74982636e9722b51d 536 Gene3D G3DSA:3.30.200.20 34 121 6.9E-25 T 06-07-2017 LK06_RS11860 9b3f44e978d0ab4435dc2f5a77afdb43 375 Gene3D G3DSA:3.40.50.10490 225 372 8.0E-8 T 06-07-2017 LK06_RS11860 9b3f44e978d0ab4435dc2f5a77afdb43 375 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 226 372 3.8E-22 T 06-07-2017 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 LK06_RS11860 9b3f44e978d0ab4435dc2f5a77afdb43 375 SUPERFAMILY SSF53697 98 372 1.33E-43 T 06-07-2017 LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 Gene3D G3DSA:1.10.486.10 470 651 1.5E-23 T 06-07-2017 LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 SUPERFAMILY SSF52980 1009 1144 2.63E-6 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 Pfam PF13361 UvrD-like helicase C-terminal domain 355 769 1.2E-27 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 Gene3D G3DSA:3.40.50.300 357 469 1.6E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 Gene3D G3DSA:3.40.50.300 747 797 1.6E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 Gene3D G3DSA:3.40.50.300 673 708 1.6E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 342 2.8E-47 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1012 1153 2.9E-10 T 06-07-2017 LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 SUPERFAMILY SSF52540 17 87 6.59E-112 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 SUPERFAMILY SSF52540 120 505 6.59E-112 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 SUPERFAMILY SSF52540 751 797 6.59E-112 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 SUPERFAMILY SSF52540 558 712 6.59E-112 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 Gene3D G3DSA:3.40.50.300 128 172 1.3E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 Gene3D G3DSA:3.40.50.300 225 345 1.3E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22205 0d9ed7de37f50ef7ca9294602c33e3f9 1183 Gene3D G3DSA:3.40.50.300 19 83 1.3E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01880 46038ef5790e1b0218c56479e277adb5 350 SMART SM00422 10 79 2.9E-4 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS01880 46038ef5790e1b0218c56479e277adb5 350 SUPERFAMILY SSF46955 11 82 6.87E-12 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS01880 46038ef5790e1b0218c56479e277adb5 350 Pfam PF00376 MerR family regulatory protein 11 47 5.4E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS01880 46038ef5790e1b0218c56479e277adb5 350 Gene3D G3DSA:1.10.1660.10 11 85 1.0E-11 T 06-07-2017 LK06_RS01880 46038ef5790e1b0218c56479e277adb5 350 Pfam PF02607 B12 binding domain 131 198 7.0E-6 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS01880 46038ef5790e1b0218c56479e277adb5 350 SUPERFAMILY SSF52242 213 272 1.12E-5 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS01880 46038ef5790e1b0218c56479e277adb5 350 Gene3D G3DSA:3.40.50.280 216 272 3.3E-4 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 Gene3D G3DSA:3.30.460.10 291 437 4.6E-49 T 06-07-2017 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 Gene3D G3DSA:3.30.70.260 775 847 5.8E-15 T 06-07-2017 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 SUPERFAMILY SSF81301 293 519 5.23E-63 T 06-07-2017 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 Pfam PF02824 TGS domain 515 574 1.2E-21 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 Pfam PF13291 ACT domain 773 849 4.1E-17 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 141 849 8.7E-258 T 06-07-2017 IPR004811 RelA/SpoT family GO:0015969 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 Gene3D G3DSA:3.10.20.30 514 576 3.7E-23 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 SUPERFAMILY SSF81271 502 574 3.92E-21 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 Pfam PF04607 Region found in RelA / SpoT proteins 348 457 8.6E-37 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 SMART SM00471 156 266 1.1E-12 T 06-07-2017 IPR003607 HD/PDEase domain LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 SUPERFAMILY SSF109604 129 303 1.29E-71 T 06-07-2017 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 SUPERFAMILY SSF55021 772 851 2.83E-15 T 06-07-2017 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 SMART SM00954 348 458 2.2E-64 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 LK06_RS04250 c3705da039098b0d49326470d95c57a6 857 Pfam PF13328 HD domain 141 288 3.1E-51 T 06-07-2017 IPR003607 HD/PDEase domain LK06_RS25335 f9d605d5811934d3f9fc586240d02b2e 227 Gene3D G3DSA:3.40.50.2300 3 127 1.2E-29 T 06-07-2017 LK06_RS25335 f9d605d5811934d3f9fc586240d02b2e 227 Pfam PF00072 Response regulator receiver domain 5 117 5.3E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25335 f9d605d5811934d3f9fc586240d02b2e 227 Pfam PF08279 HTH domain 167 207 3.0E-10 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 LK06_RS25335 f9d605d5811934d3f9fc586240d02b2e 227 SMART SM00448 3 117 4.5E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25335 f9d605d5811934d3f9fc586240d02b2e 227 SUPERFAMILY SSF52172 4 129 6.23E-32 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS25335 f9d605d5811934d3f9fc586240d02b2e 227 SUPERFAMILY SSF46785 171 224 1.51E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25335 f9d605d5811934d3f9fc586240d02b2e 227 Gene3D G3DSA:1.10.10.10 168 203 2.0E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25335 f9d605d5811934d3f9fc586240d02b2e 227 PIRSF PIRSF006171 1 227 1.1E-79 T 06-07-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 LK06_RS31145 fd8c5235ee7c8f645f655920e6ee18b0 656 Pfam PF01752 Collagenase 352 641 1.1E-102 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 LK06_RS31145 fd8c5235ee7c8f645f655920e6ee18b0 656 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 451 465 6.2E-29 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 LK06_RS31145 fd8c5235ee7c8f645f655920e6ee18b0 656 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 469 485 6.2E-29 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 LK06_RS31145 fd8c5235ee7c8f645f655920e6ee18b0 656 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 536 551 6.2E-29 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 LK06_RS31145 fd8c5235ee7c8f645f655920e6ee18b0 656 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 177 195 6.2E-29 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 LK06_RS31145 fd8c5235ee7c8f645f655920e6ee18b0 656 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 513 531 6.2E-29 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 LK06_RS31145 fd8c5235ee7c8f645f655920e6ee18b0 656 Pfam PF08453 Peptidase family M9 N-terminal 111 292 3.5E-65 T 06-07-2017 IPR013661 Peptidase M9, collagenase, N-terminal domain LK06_RS06700 08115d465a5cc8d7cb67538dff862f0c 192 Gene3D G3DSA:2.60.60.30 20 181 2.0E-46 T 06-07-2017 LK06_RS06700 08115d465a5cc8d7cb67538dff862f0c 192 Pfam PF02342 TerD domain 2 179 5.9E-44 T 06-07-2017 IPR003325 TerD domain GO:0006950 LK06_RS17045 dfc47b8f5438ee6e538f5b4b21e99037 360 Pfam PF02769 AIR synthase related protein, C-terminal domain 183 349 1.8E-31 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS17045 dfc47b8f5438ee6e538f5b4b21e99037 360 Pfam PF00586 AIR synthase related protein, N-terminal domain 67 171 9.9E-16 T 06-07-2017 IPR016188 PurM-like, N-terminal domain LK06_RS17045 dfc47b8f5438ee6e538f5b4b21e99037 360 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 12 355 40.438 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LK06_RS17045 dfc47b8f5438ee6e538f5b4b21e99037 360 SUPERFAMILY SSF55326 13 176 1.36E-44 T 06-07-2017 LK06_RS17045 dfc47b8f5438ee6e538f5b4b21e99037 360 Gene3D G3DSA:3.30.1330.10 28 176 5.3E-51 T 06-07-2017 IPR016188 PurM-like, N-terminal domain LK06_RS17045 dfc47b8f5438ee6e538f5b4b21e99037 360 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 13 344 1.8E-124 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LK06_RS17045 dfc47b8f5438ee6e538f5b4b21e99037 360 Gene3D G3DSA:3.90.650.10 180 349 2.6E-62 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS17045 dfc47b8f5438ee6e538f5b4b21e99037 360 SUPERFAMILY SSF56042 180 348 1.79E-52 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS06925 8416d6aed08fc8882f9e041df0755fce 219 SUPERFAMILY SSF52172 24 207 5.27E-57 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS06925 8416d6aed08fc8882f9e041df0755fce 219 PIRSF PIRSF036382 17 214 8.6E-71 T 06-07-2017 IPR008327 Signal transduction response regulator, antiterminator LK06_RS06925 8416d6aed08fc8882f9e041df0755fce 219 Gene3D G3DSA:1.10.10.10 154 211 1.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06925 8416d6aed08fc8882f9e041df0755fce 219 Gene3D G3DSA:3.40.50.2300 24 149 1.2E-38 T 06-07-2017 LK06_RS06925 8416d6aed08fc8882f9e041df0755fce 219 Pfam PF03861 ANTAR domain 155 207 1.3E-20 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 LK06_RS06925 8416d6aed08fc8882f9e041df0755fce 219 SMART SM00448 25 136 1.1E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS06925 8416d6aed08fc8882f9e041df0755fce 219 Pfam PF00072 Response regulator receiver domain 27 136 3.1E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS06925 8416d6aed08fc8882f9e041df0755fce 219 SMART SM01012 152 207 3.2E-23 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 LK06_RS31400 ac621d0dc5e99133375a6d8d5761f16a 313 SUPERFAMILY SSF55729 128 301 4.65E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS31400 ac621d0dc5e99133375a6d8d5761f16a 313 SUPERFAMILY SSF55729 16 141 4.15E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS31400 ac621d0dc5e99133375a6d8d5761f16a 313 Pfam PF00583 Acetyltransferase (GNAT) family 73 138 5.1E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS31400 ac621d0dc5e99133375a6d8d5761f16a 313 Pfam PF00583 Acetyltransferase (GNAT) family 220 294 3.8E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS31400 ac621d0dc5e99133375a6d8d5761f16a 313 Gene3D G3DSA:3.40.630.30 164 297 3.1E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS31400 ac621d0dc5e99133375a6d8d5761f16a 313 Gene3D G3DSA:3.40.630.30 15 139 8.2E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.9E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 168 192 1.9E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 137 1.9E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 10 208 4.3E-21 T 06-07-2017 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 SUPERFAMILY SSF51905 8 211 5.26E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 SUPERFAMILY SSF51905 237 357 6.86E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 SUPERFAMILY SSF51905 170 206 6.86E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 300 3.8E-9 T 06-07-2017 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 3.8E-9 T 06-07-2017 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.8E-9 T 06-07-2017 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 Gene3D G3DSA:3.50.50.60 149 209 1.6E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 Gene3D G3DSA:3.50.50.60 255 290 1.6E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29710 8d492e4d6b0001e4828ce9537debe434 361 Gene3D G3DSA:3.50.50.60 7 148 1.3E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 PRINTS PR00320 G protein beta WD-40 repeat signature 962 976 1.1E-8 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 PRINTS PR00320 G protein beta WD-40 repeat signature 1319 1333 1.1E-8 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 PRINTS PR00320 G protein beta WD-40 repeat signature 871 885 1.1E-8 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1227 1241 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 779 793 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SUPERFAMILY SSF50978 753 1101 2.45E-85 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1273 1287 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 825 839 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Gene3D G3DSA:2.130.10.10 1184 1395 3.1E-58 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Gene3D G3DSA:2.130.10.10 758 933 2.4E-56 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1319 1333 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 871 885 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 916 930 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Gene3D G3DSA:3.40.50.300 148 196 2.2E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 890 929 5.6E-10 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 1201 1240 5.3E-10 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 1247 1286 1.5E-9 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 1159 1194 7.0E-4 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 1293 1332 9.2E-9 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 1338 1378 19.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 1028 1067 3.3E-5 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 1070 1100 7.5 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 845 884 2.5E-6 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 753 792 3.0E-8 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 936 975 1.6E-11 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 982 1021 7.0E-9 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 1107 1146 9.2 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SMART SM00320 799 838 1.7E-10 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1008 1022 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 962 976 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1087 1101 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Gene3D G3DSA:2.130.10.10 939 1183 1.5E-58 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SUPERFAMILY SSF50978 1153 1336 3.3E-67 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 SUPERFAMILY SSF50978 994 1104 3.3E-67 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 1208 1240 7.3E-9 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 804 838 1.2E-8 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 894 929 5.6E-7 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 759 792 5.2E-6 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 1078 1100 0.11 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 1299 1332 3.0E-7 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 1043 1067 0.0043 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 988 1021 7.1E-6 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 938 975 2.4E-10 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 1256 1286 4.1E-8 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 1170 1194 2.6E-4 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 Pfam PF00400 WD domain, G-beta repeat 859 884 2.6E-5 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 LK06_RS15730 f74abd1281cd8b26df8815dcd8833b48 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1181 1195 - T 06-07-2017 IPR019775 WD40 repeat, conserved site LK06_RS29070 13a6f0aedbebce250b9b5787c3f5160a 386 Gene3D G3DSA:3.40.50.720 3 150 3.8E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29070 13a6f0aedbebce250b9b5787c3f5160a 386 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 144 228 8.0E-11 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 LK06_RS29070 13a6f0aedbebce250b9b5787c3f5160a 386 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 132 1.7E-22 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 LK06_RS29070 13a6f0aedbebce250b9b5787c3f5160a 386 SUPERFAMILY SSF51735 5 161 2.05E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29070 13a6f0aedbebce250b9b5787c3f5160a 386 Gene3D G3DSA:3.30.360.10 151 288 3.7E-44 T 06-07-2017 LK06_RS29070 13a6f0aedbebce250b9b5787c3f5160a 386 Gene3D G3DSA:3.30.360.10 335 385 3.7E-44 T 06-07-2017 LK06_RS29070 13a6f0aedbebce250b9b5787c3f5160a 386 SUPERFAMILY SSF55347 138 327 3.92E-35 T 06-07-2017 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 296 49.988 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 SUPERFAMILY SSF51569 9 297 1.67E-86 T 06-07-2017 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 Gene3D G3DSA:3.20.20.70 10 297 2.9E-94 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 PIRSF PIRSF001365 9 302 3.6E-76 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 47 64 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 SMART SM01130 10 298 2.7E-101 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 Pfam PF00701 Dihydrodipicolinate synthetase family 11 291 3.0E-69 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 15 290 5.5E-68 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 2.4E-27 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 2.4E-27 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 2.4E-27 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS06430 7a65229d18d60eee30e25186254a67ce 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 2.4E-27 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS23635 f2c2d2646990fcf5bf2ca3afd52fd0ef 708 SMART SM00642 245 596 0.0031 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS23635 f2c2d2646990fcf5bf2ca3afd52fd0ef 708 Gene3D G3DSA:2.60.40.1180 607 684 2.1E-12 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS23635 f2c2d2646990fcf5bf2ca3afd52fd0ef 708 SUPERFAMILY SSF51011 608 684 8.8E-6 T 06-07-2017 LK06_RS23635 f2c2d2646990fcf5bf2ca3afd52fd0ef 708 SUPERFAMILY SSF51445 246 603 2.62E-78 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS23635 f2c2d2646990fcf5bf2ca3afd52fd0ef 708 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 51 696 46.763 T 06-07-2017 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 LK06_RS23635 f2c2d2646990fcf5bf2ca3afd52fd0ef 708 Gene3D G3DSA:3.20.20.80 245 601 2.8E-63 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS23635 f2c2d2646990fcf5bf2ca3afd52fd0ef 708 Pfam PF11896 Domain of unknown function (DUF3416) 53 239 5.9E-58 T 06-07-2017 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 LK06_RS14065 93542bf322f8bcfa96276124c25ef677 275 Gene3D G3DSA:3.40.50.1000 86 236 1.4E-48 T 06-07-2017 IPR023214 HAD-like domain LK06_RS14065 93542bf322f8bcfa96276124c25ef677 275 SUPERFAMILY SSF56784 12 224 1.47E-30 T 06-07-2017 IPR023214 HAD-like domain LK06_RS14065 93542bf322f8bcfa96276124c25ef677 275 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 14 214 1.8E-60 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial LK06_RS14065 93542bf322f8bcfa96276124c25ef677 275 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 14 203 5.1E-21 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 LK06_RS14065 93542bf322f8bcfa96276124c25ef677 275 Pfam PF12710 haloacid dehalogenase-like hydrolase 15 201 3.0E-31 T 06-07-2017 LK06_RS27230 ff3bb7718623ec9ddbac27d4a74898c8 197 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 130 158 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 LK06_RS27230 ff3bb7718623ec9ddbac27d4a74898c8 197 Gene3D G3DSA:1.10.3130.10 4 59 6.5E-9 T 06-07-2017 LK06_RS27230 ff3bb7718623ec9ddbac27d4a74898c8 197 Gene3D G3DSA:2.160.10.10 63 164 2.5E-26 T 06-07-2017 LK06_RS27230 ff3bb7718623ec9ddbac27d4a74898c8 197 SUPERFAMILY SSF51161 5 164 1.29E-33 T 06-07-2017 IPR011004 Trimeric LpxA-like LK06_RS27230 ff3bb7718623ec9ddbac27d4a74898c8 197 PIRSF PIRSF000441 1 177 3.6E-50 T 06-07-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 LK06_RS27230 ff3bb7718623ec9ddbac27d4a74898c8 197 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 122 153 6.9E-6 T 06-07-2017 IPR001451 Hexapeptide repeat LK06_RS11145 852c1a7d096f82c82933228da7cd8c73 320 Pfam PF00005 ABC transporter 34 177 1.5E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS11145 852c1a7d096f82c82933228da7cd8c73 320 SUPERFAMILY SSF52540 27 241 5.6E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11145 852c1a7d096f82c82933228da7cd8c73 320 Gene3D G3DSA:3.40.50.300 3 248 5.1E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11145 852c1a7d096f82c82933228da7cd8c73 320 SMART SM00382 42 227 3.2E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS13695 31e64cbd37d8bb4f8a5cead0979c057c 328 Gene3D G3DSA:3.90.1170.20 49 179 1.8E-45 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 LK06_RS13695 31e64cbd37d8bb4f8a5cead0979c057c 328 SUPERFAMILY SSF54675 51 158 5.3E-27 T 06-07-2017 LK06_RS13695 31e64cbd37d8bb4f8a5cead0979c057c 328 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 70 157 4.2E-24 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 LK06_RS13695 31e64cbd37d8bb4f8a5cead0979c057c 328 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 61 323 6.1E-92 T 06-07-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 LK06_RS13695 31e64cbd37d8bb4f8a5cead0979c057c 328 SUPERFAMILY SSF51690 159 324 2.86E-58 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 LK06_RS13695 31e64cbd37d8bb4f8a5cead0979c057c 328 Gene3D G3DSA:3.20.20.70 180 314 1.7E-56 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS13695 31e64cbd37d8bb4f8a5cead0979c057c 328 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 159 323 1.9E-56 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 LK06_RS13695 31e64cbd37d8bb4f8a5cead0979c057c 328 PIRSF PIRSF006250 51 327 5.1E-95 T 06-07-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 LK06_RS31890 25f1ad5783595bf9211da87a918f0c49 411 SUPERFAMILY SSF54373 176 276 1.08E-19 T 06-07-2017 LK06_RS31890 25f1ad5783595bf9211da87a918f0c49 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 8.0E-22 T 06-07-2017 LK06_RS31890 25f1ad5783595bf9211da87a918f0c49 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 8.0E-22 T 06-07-2017 LK06_RS31890 25f1ad5783595bf9211da87a918f0c49 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 8.0E-22 T 06-07-2017 LK06_RS31890 25f1ad5783595bf9211da87a918f0c49 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 8.0E-22 T 06-07-2017 LK06_RS31890 25f1ad5783595bf9211da87a918f0c49 411 SUPERFAMILY SSF51905 271 362 4.86E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS31890 25f1ad5783595bf9211da87a918f0c49 411 SUPERFAMILY SSF51905 8 173 4.86E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS31890 25f1ad5783595bf9211da87a918f0c49 411 Gene3D G3DSA:3.50.50.60 8 178 2.3E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS31890 25f1ad5783595bf9211da87a918f0c49 411 Gene3D G3DSA:3.50.50.60 271 355 2.3E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS31890 25f1ad5783595bf9211da87a918f0c49 411 Pfam PF01494 FAD binding domain 7 344 5.2E-32 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 Pfam PF00364 Biotin-requiring enzyme 117 188 2.6E-19 T 06-07-2017 IPR000089 Biotin/lipoyl attachment LK06_RS07800 4f1671f17591eb6867293914396540f5 578 Pfam PF00364 Biotin-requiring enzyme 5 76 2.7E-21 T 06-07-2017 IPR000089 Biotin/lipoyl attachment LK06_RS07800 4f1671f17591eb6867293914396540f5 578 SUPERFAMILY SSF51230 116 209 1.05E-25 T 06-07-2017 IPR011053 Single hybrid motif LK06_RS07800 4f1671f17591eb6867293914396540f5 578 Gene3D G3DSA:2.40.50.100 1 96 3.7E-30 T 06-07-2017 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 Gene3D G3DSA:2.40.50.100 116 208 3.3E-28 T 06-07-2017 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 SUPERFAMILY SSF51230 1 96 1.13E-26 T 06-07-2017 IPR011053 Single hybrid motif LK06_RS07800 4f1671f17591eb6867293914396540f5 578 SUPERFAMILY SSF52777 330 569 7.56E-77 T 06-07-2017 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 343 569 3.6E-73 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 578 7.9E-226 T 06-07-2017 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 Gene3D G3DSA:4.10.320.10 269 319 1.3E-19 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 SUPERFAMILY SSF47005 266 310 2.62E-12 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 Gene3D G3DSA:3.30.559.10 340 569 1.7E-77 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 140 169 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 LK06_RS07800 4f1671f17591eb6867293914396540f5 578 Pfam PF02817 e3 binding domain 274 306 5.5E-15 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS23910 d80f1fe710b41d9b79713b6df9f57ce6 743 SUPERFAMILY SSF82866 462 696 4.84E-23 T 06-07-2017 LK06_RS23910 d80f1fe710b41d9b79713b6df9f57ce6 743 Gene3D G3DSA:1.20.1640.10 496 702 3.2E-25 T 06-07-2017 LK06_RS23910 d80f1fe710b41d9b79713b6df9f57ce6 743 Gene3D G3DSA:1.20.1640.10 141 338 7.6E-30 T 06-07-2017 LK06_RS23910 d80f1fe710b41d9b79713b6df9f57ce6 743 SUPERFAMILY SSF82866 117 331 5.49E-31 T 06-07-2017 LK06_RS23910 d80f1fe710b41d9b79713b6df9f57ce6 743 Pfam PF03176 MMPL family 44 367 1.7E-66 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS23910 d80f1fe710b41d9b79713b6df9f57ce6 743 Pfam PF03176 MMPL family 447 696 7.6E-29 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS25390 41fa08c2108f37b19ac77be3389eddc0 93 PRINTS PR00107 Phosphocarrier protein signature 39 54 2.0E-9 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like LK06_RS25390 41fa08c2108f37b19ac77be3389eddc0 93 PRINTS PR00107 Phosphocarrier protein signature 54 71 2.0E-9 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like LK06_RS25390 41fa08c2108f37b19ac77be3389eddc0 93 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.0E-9 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like LK06_RS25390 41fa08c2108f37b19ac77be3389eddc0 93 Gene3D G3DSA:3.30.1340.10 1 88 1.5E-23 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like LK06_RS25390 41fa08c2108f37b19ac77be3389eddc0 93 SUPERFAMILY SSF55594 1 88 3.79E-19 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like LK06_RS25390 41fa08c2108f37b19ac77be3389eddc0 93 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 06-07-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site LK06_RS25390 41fa08c2108f37b19ac77be3389eddc0 93 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 1.1E-24 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like LK06_RS25390 41fa08c2108f37b19ac77be3389eddc0 93 Pfam PF00381 PTS HPr component phosphorylation site 3 83 3.7E-21 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like LK06_RS12595 b7d6ea29d834ef0b2c5a7a3698a701da 162 Gene3D G3DSA:3.30.70.860 97 162 3.5E-30 T 06-07-2017 LK06_RS12595 b7d6ea29d834ef0b2c5a7a3698a701da 162 Gene3D G3DSA:3.30.70.990 11 96 4.4E-31 T 06-07-2017 LK06_RS12595 b7d6ea29d834ef0b2c5a7a3698a701da 162 Pfam PF04461 Protein of unknown function (DUF520) 4 162 5.4E-62 T 06-07-2017 IPR007551 Protein of unknown function DUF520 LK06_RS12595 b7d6ea29d834ef0b2c5a7a3698a701da 162 SUPERFAMILY SSF89963 5 87 6.28E-29 T 06-07-2017 IPR007551 Protein of unknown function DUF520 LK06_RS12595 b7d6ea29d834ef0b2c5a7a3698a701da 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 162 25.992 T 06-07-2017 IPR007551 Protein of unknown function DUF520 LK06_RS12595 b7d6ea29d834ef0b2c5a7a3698a701da 162 SUPERFAMILY SSF89963 90 162 2.41E-24 T 06-07-2017 IPR007551 Protein of unknown function DUF520 LK06_RS02555 fa0226ea34b5da3fb91b73c76a7eb627 329 Pfam PF02195 ParB-like nuclease domain 41 93 1.9E-5 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS02555 fa0226ea34b5da3fb91b73c76a7eb627 329 Gene3D G3DSA:3.90.1530.10 12 95 8.9E-6 T 06-07-2017 LK06_RS02555 fa0226ea34b5da3fb91b73c76a7eb627 329 SUPERFAMILY SSF110849 16 94 1.71E-7 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS02555 fa0226ea34b5da3fb91b73c76a7eb627 329 SMART SM00470 10 94 7.0E-5 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS04795 a9abc6b09007adfb01a37a38b65480da 374 Gene3D G3DSA:3.30.930.10 25 371 2.3E-118 T 06-07-2017 LK06_RS04795 a9abc6b09007adfb01a37a38b65480da 374 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 70 368 1.0E-87 T 06-07-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 LK06_RS04795 a9abc6b09007adfb01a37a38b65480da 374 Pfam PF01409 tRNA synthetases class II core domain (F) 109 369 3.7E-104 T 06-07-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 LK06_RS04795 a9abc6b09007adfb01a37a38b65480da 374 SUPERFAMILY SSF46589 29 115 4.97E-13 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 LK06_RS04795 a9abc6b09007adfb01a37a38b65480da 374 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 370 45.818 T 06-07-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 LK06_RS04795 a9abc6b09007adfb01a37a38b65480da 374 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 104 3.3E-14 T 06-07-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 LK06_RS04795 a9abc6b09007adfb01a37a38b65480da 374 SUPERFAMILY SSF55681 109 371 7.59E-77 T 06-07-2017 LK06_RS30740 d7f3da9983e9de9089917e23e67255a7 356 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 346 1.9E-80 T 06-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 LK06_RS30740 d7f3da9983e9de9089917e23e67255a7 356 Pfam PF00962 Adenosine/AMP deaminase 14 345 2.6E-77 T 06-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 LK06_RS30740 d7f3da9983e9de9089917e23e67255a7 356 Hamap MF_00540 Adenosine deaminase [add]. 9 348 53.962 T 06-07-2017 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 LK06_RS30740 d7f3da9983e9de9089917e23e67255a7 356 Gene3D G3DSA:3.20.20.140 11 347 1.6E-101 T 06-07-2017 LK06_RS30740 d7f3da9983e9de9089917e23e67255a7 356 SUPERFAMILY SSF51556 10 344 2.78E-76 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS05970 8cd2ac8e324754255009a25e69680208 248 SUPERFAMILY SSF46785 7 78 1.03E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05970 8cd2ac8e324754255009a25e69680208 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 1.4E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05970 8cd2ac8e324754255009a25e69680208 248 SMART SM00895 95 218 8.1E-18 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS05970 8cd2ac8e324754255009a25e69680208 248 SUPERFAMILY SSF48008 92 212 3.66E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS05970 8cd2ac8e324754255009a25e69680208 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.9E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05970 8cd2ac8e324754255009a25e69680208 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.9E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05970 8cd2ac8e324754255009a25e69680208 248 Gene3D G3DSA:1.20.120.530 91 211 6.0E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS05970 8cd2ac8e324754255009a25e69680208 248 Gene3D G3DSA:1.10.10.10 7 77 1.8E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05970 8cd2ac8e324754255009a25e69680208 248 Pfam PF07729 FCD domain 96 210 1.5E-23 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS05970 8cd2ac8e324754255009a25e69680208 248 SMART SM00345 15 74 9.3E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 Gene3D G3DSA:3.20.20.330 16 358 2.3E-104 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 SUPERFAMILY SSF52242 732 866 7.33E-38 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 Pfam PF02574 Homocysteine S-methyltransferase 28 319 1.4E-67 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 Gene3D G3DSA:1.10.1240.10 643 728 7.6E-31 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 Gene3D G3DSA:3.10.196.10 957 1172 6.0E-71 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 SUPERFAMILY SSF47644 647 730 7.32E-24 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 SUPERFAMILY SSF56507 900 1173 1.7E-93 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 Pfam PF00809 Pterin binding enzyme 354 590 2.1E-44 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 Gene3D G3DSA:3.20.20.20 359 620 1.5E-83 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 SUPERFAMILY SSF51717 351 622 5.1E-73 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 Pfam PF02310 B12 binding domain 737 855 4.2E-21 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 SUPERFAMILY SSF82282 19 393 2.88E-103 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 TIGRFAM TIGR02082 metH: methionine synthase 24 1172 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 Pfam PF02607 B12 binding domain 652 724 5.0E-24 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 Gene3D G3DSA:3.40.50.280 734 864 1.5E-46 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 972 1172 1.3E-40 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 SMART SM01018 649 731 7.3E-41 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS05095 d6b890f0057ed40768c884fc914531b7 1174 PIRSF PIRSF000381 12 1174 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS09980 b647ddb6ec753159041e872d1d5bd4f7 472 PIRSF PIRSF006060 2 464 1.7E-69 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS09980 b647ddb6ec753159041e872d1d5bd4f7 472 Pfam PF00324 Amino acid permease 15 422 5.3E-114 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 LK06_RS09980 b647ddb6ec753159041e872d1d5bd4f7 472 ProSitePatterns PS00218 Amino acid permeases signature. 40 70 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 Pfam PF00072 Response regulator receiver domain 17 76 7.2E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 204 220 1.0E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 220 232 1.0E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 204 1.0E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 SMART SM00448 15 151 1.5E-14 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 SUPERFAMILY SSF46894 177 249 2.93E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 Gene3D G3DSA:1.10.10.10 189 249 1.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 SUPERFAMILY SSF52172 15 161 1.57E-16 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 Pfam PF00196 Bacterial regulatory proteins, luxR family 189 244 9.7E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 SMART SM00421 187 244 2.1E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS19780 a27a5082ac17c677c41cc0f3bc9baaec 266 Gene3D G3DSA:3.40.50.2300 14 188 2.6E-37 T 06-07-2017 LK06_RS07620 0edb4c5af002f393b092ef29b9ce4c96 355 Gene3D G3DSA:2.102.10.10 216 354 3.2E-36 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS07620 0edb4c5af002f393b092ef29b9ce4c96 355 Gene3D G3DSA:2.102.10.10 160 177 3.2E-36 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS07620 0edb4c5af002f393b092ef29b9ce4c96 355 SUPERFAMILY SSF50022 172 354 9.04E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS07620 0edb4c5af002f393b092ef29b9ce4c96 355 Pfam PF00355 Rieske [2Fe-2S] domain 238 326 2.0E-10 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 3.0E-41 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 558 4.7E-12 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Gene3D G3DSA:1.10.1200.10 1476 1550 1.5E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Gene3D G3DSA:3.40.47.10 297 462 1.1E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Pfam PF00698 Acyl transferase domain 593 911 1.2E-78 T 06-07-2017 IPR014043 Acyl transferase LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Gene3D G3DSA:3.40.47.10 30 296 1.3E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SUPERFAMILY SSF52151 592 720 1.52E-65 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SUPERFAMILY SSF52151 785 881 1.52E-65 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SMART SM00825 Beta-ketoacyl synthase 36 462 1.9E-215 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SMART SM00824 Thioesterase 1619 1824 1.5E-94 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SUPERFAMILY SSF53474 1507 1545 1.56E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SUPERFAMILY SSF53474 1594 1826 1.56E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 595 893 1.1E-99 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Pfam PF00550 Phosphopantetheine attachment site 1480 1545 9.9E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.0E-88 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SUPERFAMILY SSF55048 719 780 1.7E-5 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SUPERFAMILY SSF47336 1469 1559 2.09E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Pfam PF08659 KR domain 1199 1375 1.4E-41 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SMART SM00823 Phosphopantetheine attachment site 1477 1549 6.6E-24 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Gene3D G3DSA:3.40.50.720 1199 1375 5.4E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Pfam PF08990 Erythronolide synthase docking 6 27 9.9E-9 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SUPERFAMILY SSF51735 1001 1186 1.02E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Gene3D G3DSA:3.40.50.1820 1566 1825 7.9E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SUPERFAMILY SSF53901 28 400 6.19E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Pfam PF00975 Thioesterase domain 1618 1823 1.3E-15 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SUPERFAMILY SSF51735 1195 1433 3.61E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Gene3D G3DSA:3.40.366.10 585 715 2.5E-72 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 Gene3D G3DSA:3.40.366.10 784 905 2.5E-72 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1199 1376 1.5E-28 T 06-07-2017 LK06_RS29425 7b8c790e55799f9b39662384b147813a 1827 SMART SM01294 1478 1545 0.0026 T 06-07-2017 LK06_RS31255 4cd87230f34dd5ac647ce35c5d3728bb 193 Gene3D G3DSA:3.40.50.1450 4 154 7.4E-35 T 06-07-2017 IPR023430 Peptidase HybD-like domain LK06_RS31255 4cd87230f34dd5ac647ce35c5d3728bb 193 PRINTS PR00446 Hydrogen uptake protein signature 69 85 1.3E-8 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS31255 4cd87230f34dd5ac647ce35c5d3728bb 193 PRINTS PR00446 Hydrogen uptake protein signature 36 53 1.3E-8 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS31255 4cd87230f34dd5ac647ce35c5d3728bb 193 PRINTS PR00446 Hydrogen uptake protein signature 17 28 1.3E-8 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS31255 4cd87230f34dd5ac647ce35c5d3728bb 193 PRINTS PR00446 Hydrogen uptake protein signature 5 17 1.3E-8 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS31255 4cd87230f34dd5ac647ce35c5d3728bb 193 Pfam PF01750 Hydrogenase maturation protease 23 150 5.6E-8 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS31255 4cd87230f34dd5ac647ce35c5d3728bb 193 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 6 151 5.9E-29 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 LK06_RS31255 4cd87230f34dd5ac647ce35c5d3728bb 193 SUPERFAMILY SSF53163 4 153 1.83E-29 T 06-07-2017 IPR023430 Peptidase HybD-like domain LK06_RS26430 4fdcfd1a49b8cd63308515e85bc53a7f 90 PRINTS PR00352 3Fe-4S ferredoxin signature 61 73 3.9E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS26430 4fdcfd1a49b8cd63308515e85bc53a7f 90 PRINTS PR00352 3Fe-4S ferredoxin signature 18 29 3.9E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS26430 4fdcfd1a49b8cd63308515e85bc53a7f 90 PRINTS PR00352 3Fe-4S ferredoxin signature 29 39 3.9E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS26430 4fdcfd1a49b8cd63308515e85bc53a7f 90 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 18 72 6.9E-12 T 06-07-2017 LK06_RS26430 4fdcfd1a49b8cd63308515e85bc53a7f 90 SUPERFAMILY SSF54862 16 75 1.54E-10 T 06-07-2017 LK06_RS26430 4fdcfd1a49b8cd63308515e85bc53a7f 90 Gene3D G3DSA:3.30.70.20 16 75 1.1E-12 T 06-07-2017 LK06_RS11970 c8f128967b17d820276dc4ecb4e2a354 140 Gene3D G3DSA:3.40.50.150 54 139 1.1E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS11970 c8f128967b17d820276dc4ecb4e2a354 140 SUPERFAMILY SSF53335 44 140 1.6E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 SUPERFAMILY SSF55031 283 339 2.33E-10 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 SUPERFAMILY SSF55031 197 239 2.33E-10 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 Gene3D G3DSA:3.30.70.360 284 328 4.4E-20 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 Gene3D G3DSA:3.30.70.360 207 246 4.4E-20 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 Pfam PF07687 Peptidase dimerisation domain 195 318 5.6E-11 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 Gene3D G3DSA:3.40.630.10 369 432 1.7E-55 T 06-07-2017 LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 Gene3D G3DSA:3.40.630.10 6 206 1.7E-55 T 06-07-2017 LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 111 150 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 Pfam PF01546 Peptidase family M20/M25/M40 77 432 3.8E-37 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 76 85 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 SUPERFAMILY SSF53187 5 197 8.86E-52 T 06-07-2017 LK06_RS28045 3e25b75e8090834b2da3f3a2e1be28c1 434 SUPERFAMILY SSF53187 344 432 8.86E-52 T 06-07-2017 LK06_RS12530 f06b97efbdb020fbd4817d65789352d4 421 Gene3D G3DSA:2.30.40.10 25 88 8.2E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS12530 f06b97efbdb020fbd4817d65789352d4 421 Gene3D G3DSA:3.20.20.140 100 354 6.3E-59 T 06-07-2017 LK06_RS12530 f06b97efbdb020fbd4817d65789352d4 421 SUPERFAMILY SSF51338 25 95 3.7E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS12530 f06b97efbdb020fbd4817d65789352d4 421 SUPERFAMILY SSF51556 81 363 3.1E-47 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS31515 6babd3754e5d273e0c295f70391c22d5 494 Gene3D G3DSA:3.30.300.30 397 493 5.9E-30 T 06-07-2017 LK06_RS31515 6babd3754e5d273e0c295f70391c22d5 494 Gene3D G3DSA:3.40.50.980 3 158 9.3E-29 T 06-07-2017 LK06_RS31515 6babd3754e5d273e0c295f70391c22d5 494 Pfam PF00501 AMP-binding enzyme 8 402 7.3E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS31515 6babd3754e5d273e0c295f70391c22d5 494 SUPERFAMILY SSF56801 2 493 4.97E-134 T 06-07-2017 LK06_RS31515 6babd3754e5d273e0c295f70391c22d5 494 Gene3D G3DSA:3.40.50.980 159 307 1.4E-30 T 06-07-2017 LK06_RS31515 6babd3754e5d273e0c295f70391c22d5 494 Gene3D G3DSA:2.30.38.10 322 396 3.4E-25 T 06-07-2017 LK06_RS31515 6babd3754e5d273e0c295f70391c22d5 494 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 484 4.9E-21 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS04345 88419c56ba26cef183ebf1fe6b4ce459 185 Pfam PF01230 HIT domain 62 151 1.6E-10 T 06-07-2017 IPR001310 Histidine triad (HIT) protein LK06_RS04345 88419c56ba26cef183ebf1fe6b4ce459 185 Gene3D G3DSA:3.30.428.10 46 183 9.2E-38 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS04345 88419c56ba26cef183ebf1fe6b4ce459 185 SUPERFAMILY SSF54197 22 182 2.63E-40 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS13455 4aa2d218e3c0c1b3e2ebf7699c387f25 353 Pfam PF01553 Acyltransferase 125 256 6.7E-17 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS13455 4aa2d218e3c0c1b3e2ebf7699c387f25 353 Gene3D G3DSA:3.40.1130.10 112 265 1.0E-5 T 06-07-2017 LK06_RS13455 4aa2d218e3c0c1b3e2ebf7699c387f25 353 SMART SM00563 140 259 3.4E-17 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS13455 4aa2d218e3c0c1b3e2ebf7699c387f25 353 SUPERFAMILY SSF69593 112 344 2.09E-33 T 06-07-2017 LK06_RS19110 114757f3bdc16d413225776d74ece7eb 284 Pfam PF01569 PAP2 superfamily 191 271 3.4E-8 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS19110 114757f3bdc16d413225776d74ece7eb 284 SUPERFAMILY SSF48317 190 277 2.09E-10 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS19110 114757f3bdc16d413225776d74ece7eb 284 Gene3D G3DSA:1.20.144.10 105 275 7.1E-9 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS18885 9df56d8fedd7c280c60d4903bc9a05bd 390 PIRSF PIRSF000429 2 376 6.6E-30 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS18885 9df56d8fedd7c280c60d4903bc9a05bd 390 Gene3D G3DSA:3.40.47.10 243 359 3.0E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18885 9df56d8fedd7c280c60d4903bc9a05bd 390 Gene3D G3DSA:3.40.47.10 146 183 3.0E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18885 9df56d8fedd7c280c60d4903bc9a05bd 390 SUPERFAMILY SSF53901 8 228 4.57E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18885 9df56d8fedd7c280c60d4903bc9a05bd 390 Gene3D G3DSA:3.40.47.10 193 224 2.1E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18885 9df56d8fedd7c280c60d4903bc9a05bd 390 Gene3D G3DSA:3.40.47.10 23 110 2.1E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18885 9df56d8fedd7c280c60d4903bc9a05bd 390 SUPERFAMILY SSF53901 242 361 5.27E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18885 9df56d8fedd7c280c60d4903bc9a05bd 390 Pfam PF02803 Thiolase, C-terminal domain 245 355 1.6E-6 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 LK06_RS14390 3db69e768a80b49e6e2a2025af0a619d 176 Pfam PF12802 MarR family 50 107 3.2E-10 T 06-07-2017 LK06_RS14390 3db69e768a80b49e6e2a2025af0a619d 176 Gene3D G3DSA:1.10.10.10 17 153 1.8E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14390 3db69e768a80b49e6e2a2025af0a619d 176 ProSitePatterns PS01117 MarR-type HTH domain signature. 82 116 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site LK06_RS14390 3db69e768a80b49e6e2a2025af0a619d 176 SMART SM00347 43 143 3.6E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS14390 3db69e768a80b49e6e2a2025af0a619d 176 SUPERFAMILY SSF46785 24 158 1.02E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15515 c0ec6d73564885b2b88846fd66e66b13 380 SUPERFAMILY SSF56645 2 222 4.58E-27 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS15515 c0ec6d73564885b2b88846fd66e66b13 380 SUPERFAMILY SSF47203 237 372 5.96E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS15515 c0ec6d73564885b2b88846fd66e66b13 380 Gene3D G3DSA:2.40.110.10 131 225 8.5E-9 T 06-07-2017 LK06_RS15515 c0ec6d73564885b2b88846fd66e66b13 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 362 1.5E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS15515 c0ec6d73564885b2b88846fd66e66b13 380 Gene3D G3DSA:1.10.540.10 2 111 1.1E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS15515 c0ec6d73564885b2b88846fd66e66b13 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 3.5E-8 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS15515 c0ec6d73564885b2b88846fd66e66b13 380 Gene3D G3DSA:1.20.140.10 238 363 2.5E-24 T 06-07-2017 LK06_RS07535 738ae0b117f6c93c1d8bb3b502766aa3 390 SUPERFAMILY SSF52540 1 266 1.03E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07535 738ae0b117f6c93c1d8bb3b502766aa3 390 Pfam PF02374 Anion-transporting ATPase 1 294 1.4E-33 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 LK06_RS07535 738ae0b117f6c93c1d8bb3b502766aa3 390 Gene3D G3DSA:3.40.50.300 1 272 5.9E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09505 f3e5c0880836f5c91f880e4479e34643 240 Pfam PF00753 Metallo-beta-lactamase superfamily 26 217 1.7E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS09505 f3e5c0880836f5c91f880e4479e34643 240 SMART SM00849 26 217 1.1E-17 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS09505 f3e5c0880836f5c91f880e4479e34643 240 Gene3D G3DSA:3.60.15.10 7 236 2.2E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS09505 f3e5c0880836f5c91f880e4479e34643 240 SUPERFAMILY SSF56281 6 235 7.18E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS02105 ef29b5fed7ec9530a58a913e71c2a545 361 Gene3D G3DSA:3.40.390.10 31 254 1.1E-22 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 LK06_RS02105 ef29b5fed7ec9530a58a913e71c2a545 361 Pfam PF01400 Astacin (Peptidase family M12A) 74 163 5.0E-6 T 06-07-2017 IPR001506 Peptidase M12A, astacin GO:0004222|GO:0006508 LK06_RS02105 ef29b5fed7ec9530a58a913e71c2a545 361 SUPERFAMILY SSF55486 27 171 1.54E-18 T 06-07-2017 LK06_RS02105 ef29b5fed7ec9530a58a913e71c2a545 361 SMART SM00235 31 202 0.0046 T 06-07-2017 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 LK06_RS28010 9b3cb18a0b7a92ac2b8d8fe368afda63 520 Pfam PF00561 alpha/beta hydrolase fold 83 261 5.4E-32 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS28010 9b3cb18a0b7a92ac2b8d8fe368afda63 520 SUPERFAMILY SSF53474 316 473 1.38E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28010 9b3cb18a0b7a92ac2b8d8fe368afda63 520 SUPERFAMILY SSF53474 83 135 1.38E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28010 9b3cb18a0b7a92ac2b8d8fe368afda63 520 SUPERFAMILY SSF53474 178 232 1.38E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28010 9b3cb18a0b7a92ac2b8d8fe368afda63 520 Gene3D G3DSA:3.40.50.1820 49 133 5.5E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28010 9b3cb18a0b7a92ac2b8d8fe368afda63 520 Gene3D G3DSA:3.40.50.1820 176 300 5.5E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28010 9b3cb18a0b7a92ac2b8d8fe368afda63 520 Gene3D G3DSA:3.40.50.1820 354 473 5.5E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28010 9b3cb18a0b7a92ac2b8d8fe368afda63 520 Pfam PF08386 TAP-like protein 387 488 1.0E-21 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal LK06_RS02625 400a6ed7fd82d70a9b7571226b19d6db 284 SUPERFAMILY SSF53474 8 283 9.38E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02625 400a6ed7fd82d70a9b7571226b19d6db 284 Pfam PF00561 alpha/beta hydrolase fold 27 265 5.2E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS02625 400a6ed7fd82d70a9b7571226b19d6db 284 Gene3D G3DSA:3.40.50.1820 10 283 1.2E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS13050 10a19a2e1e5a17e76ed87d4c3c2df486 387 SUPERFAMILY SSF102114 16 361 1.18E-44 T 06-07-2017 LK06_RS13050 10a19a2e1e5a17e76ed87d4c3c2df486 387 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 7 371 48.551 T 06-07-2017 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 LK06_RS13050 10a19a2e1e5a17e76ed87d4c3c2df486 387 PIRSF PIRSF004762 2 380 1.0E-100 T 06-07-2017 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 LK06_RS13050 10a19a2e1e5a17e76ed87d4c3c2df486 387 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 10 367 4.9E-164 T 06-07-2017 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 LK06_RS13050 10a19a2e1e5a17e76ed87d4c3c2df486 387 Gene3D G3DSA:3.20.20.70 17 360 8.0E-57 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS13050 10a19a2e1e5a17e76ed87d4c3c2df486 387 Pfam PF04055 Radical SAM superfamily 61 231 4.7E-11 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS13050 10a19a2e1e5a17e76ed87d4c3c2df486 387 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 52 368 9.2E-92 T 06-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 LK06_RS23915 b4c59aad6da938081c60c20f7a60c789 209 SUPERFAMILY SSF55729 8 175 9.19E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS23915 b4c59aad6da938081c60c20f7a60c789 209 Gene3D G3DSA:3.40.630.30 11 181 4.4E-39 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS23915 b4c59aad6da938081c60c20f7a60c789 209 Pfam PF13302 Acetyltransferase (GNAT) domain 12 151 2.8E-16 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS24115 3ac672c7c5282db5dee678cf7a6e8b07 1201 Gene3D G3DSA:3.30.565.10 509 653 4.5E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24115 3ac672c7c5282db5dee678cf7a6e8b07 1201 Pfam PF08376 Nitrate and nitrite sensing 69 321 1.1E-43 T 06-07-2017 IPR013587 Nitrate/nitrite sensing protein LK06_RS24115 3ac672c7c5282db5dee678cf7a6e8b07 1201 SMART SM00387 541 652 1.5E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24115 3ac672c7c5282db5dee678cf7a6e8b07 1201 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 544 650 3.0E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24115 3ac672c7c5282db5dee678cf7a6e8b07 1201 SUPERFAMILY SSF55874 531 649 7.07E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24115 3ac672c7c5282db5dee678cf7a6e8b07 1201 SMART SM00304 359 429 8.1E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS24115 3ac672c7c5282db5dee678cf7a6e8b07 1201 Pfam PF00672 HAMP domain 340 425 7.6E-19 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS11530 9516a6b8bcfd64de4458db029ba4e45a 386 SUPERFAMILY SSF69618 18 279 4.05E-57 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS11530 9516a6b8bcfd64de4458db029ba4e45a 386 Pfam PF02602 Uroporphyrinogen-III synthase HemD 30 272 5.3E-39 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS11530 9516a6b8bcfd64de4458db029ba4e45a 386 Gene3D G3DSA:1.10.10.10 289 374 1.8E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11530 9516a6b8bcfd64de4458db029ba4e45a 386 Gene3D G3DSA:3.40.50.10090 15 144 2.6E-32 T 06-07-2017 LK06_RS11530 9516a6b8bcfd64de4458db029ba4e45a 386 Gene3D G3DSA:3.40.50.10090 146 281 1.2E-36 T 06-07-2017 LK06_RS11530 9516a6b8bcfd64de4458db029ba4e45a 386 SUPERFAMILY SSF46894 287 373 2.66E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS11530 9516a6b8bcfd64de4458db029ba4e45a 386 SMART SM00862 302 373 4.4E-13 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS11530 9516a6b8bcfd64de4458db029ba4e45a 386 Pfam PF00486 Transcriptional regulatory protein, C terminal 310 373 1.2E-12 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS08865 48b106e2af04e6ee9be68256cbb00b1f 423 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 1.1E-31 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS08865 48b106e2af04e6ee9be68256cbb00b1f 423 PIRSF PIRSF000447 3 423 2.9E-143 T 06-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 LK06_RS08865 48b106e2af04e6ee9be68256cbb00b1f 423 Gene3D G3DSA:3.40.47.10 10 264 2.4E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08865 48b106e2af04e6ee9be68256cbb00b1f 423 SUPERFAMILY SSF53901 6 258 1.3E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08865 48b106e2af04e6ee9be68256cbb00b1f 423 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 6 421 1.5E-149 T 06-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 LK06_RS08865 48b106e2af04e6ee9be68256cbb00b1f 423 Gene3D G3DSA:3.40.47.10 270 422 5.9E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08865 48b106e2af04e6ee9be68256cbb00b1f 423 SMART SM00825 Beta-ketoacyl synthase 8 414 3.6E-12 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS08865 48b106e2af04e6ee9be68256cbb00b1f 423 SUPERFAMILY SSF53901 220 422 2.39E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08865 48b106e2af04e6ee9be68256cbb00b1f 423 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 253 5.0E-54 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS00685 dfd50dfdc0be3a3be64eafe4088e4da8 115 Pfam PF05331 Protein of unknown function (DUF742) 6 115 1.8E-33 T 06-07-2017 IPR007995 Protein of unknown function DUF742 LK06_RS31970 458744c59242d8c4c64e4da08e0f1a9a 106 Pfam PF08388 Group II intron, maturase-specific domain 27 79 2.2E-8 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS31090 9ee8210c2b0bce6db95af7f049d3dbf5 368 SMART SM00331 147 363 1.9E-25 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS31090 9ee8210c2b0bce6db95af7f049d3dbf5 368 SUPERFAMILY SSF81606 160 361 5.23E-7 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS31090 9ee8210c2b0bce6db95af7f049d3dbf5 368 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 174 361 9.5E-41 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS18945 f58a5a07b22b0c09099257c79601f693 135 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 51 125 4.2E-19 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal LK06_RS18945 f58a5a07b22b0c09099257c79601f693 135 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 14 48 3.1E-12 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal LK06_RS18945 f58a5a07b22b0c09099257c79601f693 135 SUPERFAMILY SSF50249 3 125 9.42E-33 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS31230 e0f15fa6bff0dd5e35015fb31b56259a 280 Pfam PF01183 Glycosyl hydrolases family 25 78 262 1.3E-50 T 06-07-2017 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 LK06_RS31230 e0f15fa6bff0dd5e35015fb31b56259a 280 SMART SM00641 75 184 6.2E-42 T 06-07-2017 IPR018077 Glycoside hydrolase, family 25 subgroup LK06_RS31230 e0f15fa6bff0dd5e35015fb31b56259a 280 SUPERFAMILY SSF51445 76 278 3.51E-61 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS31230 e0f15fa6bff0dd5e35015fb31b56259a 280 Gene3D G3DSA:3.20.20.80 76 278 3.4E-67 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS02015 36bc5a07c80a238a3cdf6ffd44e472d4 426 Gene3D G3DSA:3.40.710.10 108 414 1.3E-69 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS02015 36bc5a07c80a238a3cdf6ffd44e472d4 426 SUPERFAMILY SSF56601 94 414 4.09E-69 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS02015 36bc5a07c80a238a3cdf6ffd44e472d4 426 Pfam PF00144 Beta-lactamase 94 399 9.7E-54 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS20775 a69e29f0c01b4c3894a9d56fa5dccf8c 258 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 90 239 6.9E-26 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20775 a69e29f0c01b4c3894a9d56fa5dccf8c 258 Gene3D G3DSA:1.10.1740.10 84 159 1.5E-17 T 06-07-2017 LK06_RS20775 a69e29f0c01b4c3894a9d56fa5dccf8c 258 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 85 241 4.7E-63 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 LK06_RS20775 a69e29f0c01b4c3894a9d56fa5dccf8c 258 Gene3D G3DSA:1.10.10.10 180 239 8.1E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20775 a69e29f0c01b4c3894a9d56fa5dccf8c 258 Pfam PF08281 Sigma-70, region 4 186 237 1.5E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20775 a69e29f0c01b4c3894a9d56fa5dccf8c 258 SUPERFAMILY SSF88946 85 172 1.73E-15 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20775 a69e29f0c01b4c3894a9d56fa5dccf8c 258 Pfam PF04542 Sigma-70 region 2 96 159 1.2E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20775 a69e29f0c01b4c3894a9d56fa5dccf8c 258 SUPERFAMILY SSF88659 178 239 2.24E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 Gene3D G3DSA:4.10.860.10 662 709 1.0E-9 T 06-07-2017 IPR001943 UVR domain GO:0005515 LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 Pfam PF12344 Ultra-violet resistance protein B 559 600 2.7E-20 T 06-07-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 Gene3D G3DSA:3.40.50.300 286 346 1.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 Gene3D G3DSA:3.40.50.300 396 417 1.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 Gene3D G3DSA:3.40.50.300 15 98 1.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 SUPERFAMILY SSF46600 666 708 9.42E-8 T 06-07-2017 IPR001943 UVR domain GO:0005515 LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 SUPERFAMILY SSF52540 13 422 1.1E-135 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 SMART SM00487 18 433 5.7E-27 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 SMART SM00490 467 553 2.4E-18 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 Gene3D G3DSA:3.30.2060.10 170 237 1.2E-11 T 06-07-2017 LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 705 42.765 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 Gene3D G3DSA:3.40.50.300 426 589 1.2E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 703 0.0 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 Pfam PF00271 Helicase conserved C-terminal domain 439 552 1.5E-19 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 SUPERFAMILY SSF52540 42 91 8.45E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 SUPERFAMILY SSF52540 466 587 8.45E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06705 928a3efc00c4a5075f748eb6d30d5ba0 715 Pfam PF04851 Type III restriction enzyme, res subunit 25 134 3.7E-9 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 LK06_RS02365 feb1190c844c0b0f8fcd4841702ec31f 375 Gene3D G3DSA:3.40.640.10 48 261 7.3E-74 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS02365 feb1190c844c0b0f8fcd4841702ec31f 375 Pfam PF00155 Aminotransferase class I and II 31 370 3.8E-54 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS02365 feb1190c844c0b0f8fcd4841702ec31f 375 SUPERFAMILY SSF53383 27 372 1.48E-91 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS02365 feb1190c844c0b0f8fcd4841702ec31f 375 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 225 234 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 LK06_RS02365 feb1190c844c0b0f8fcd4841702ec31f 375 Gene3D G3DSA:3.90.1150.10 262 370 2.7E-13 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS07340 861e64fcfaf3914ae9ef566a224b49d5 318 SUPERFAMILY SSF81799 117 218 7.85E-33 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS07340 861e64fcfaf3914ae9ef566a224b49d5 318 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 312 4.9E-94 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS07340 861e64fcfaf3914ae9ef566a224b49d5 318 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 6 313 36.815 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS07340 861e64fcfaf3914ae9ef566a224b49d5 318 Gene3D G3DSA:1.10.150.170 116 220 6.8E-36 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS07340 861e64fcfaf3914ae9ef566a224b49d5 318 Gene3D G3DSA:3.40.50.150 221 315 7.1E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07340 861e64fcfaf3914ae9ef566a224b49d5 318 Gene3D G3DSA:3.40.50.150 6 113 7.1E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07340 861e64fcfaf3914ae9ef566a224b49d5 318 SUPERFAMILY SSF53335 6 116 6.44E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07340 861e64fcfaf3914ae9ef566a224b49d5 318 SUPERFAMILY SSF53335 218 313 6.44E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07340 861e64fcfaf3914ae9ef566a224b49d5 318 Pfam PF01795 MraW methylase family 4 312 2.1E-113 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS07340 861e64fcfaf3914ae9ef566a224b49d5 318 PIRSF PIRSF004486 1 314 1.7E-99 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS24625 e02bbb073e734e18ad7438993a4abb83 415 Gene3D G3DSA:3.40.190.10 94 205 1.8E-12 T 06-07-2017 LK06_RS24625 e02bbb073e734e18ad7438993a4abb83 415 Pfam PF13416 Bacterial extracellular solute-binding protein 99 373 7.9E-32 T 06-07-2017 LK06_RS24625 e02bbb073e734e18ad7438993a4abb83 415 SUPERFAMILY SSF53850 74 411 4.0E-63 T 06-07-2017 LK06_RS24625 e02bbb073e734e18ad7438993a4abb83 415 Gene3D G3DSA:3.40.190.10 206 361 7.4E-43 T 06-07-2017 LK06_RS28005 763dc839a4f73fa9972e480f66d3c994 190 SMART SM00567 E-Z type HEAT repeats 106 137 1100.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 LK06_RS28005 763dc839a4f73fa9972e480f66d3c994 190 SMART SM00567 E-Z type HEAT repeats 76 105 490.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 LK06_RS28005 763dc839a4f73fa9972e480f66d3c994 190 SMART SM00567 E-Z type HEAT repeats 145 174 6.1 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 LK06_RS28005 763dc839a4f73fa9972e480f66d3c994 190 SMART SM00567 E-Z type HEAT repeats 45 74 22.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 LK06_RS28005 763dc839a4f73fa9972e480f66d3c994 190 SUPERFAMILY SSF48371 48 185 1.15E-8 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS28005 763dc839a4f73fa9972e480f66d3c994 190 Gene3D G3DSA:1.25.10.10 48 92 7.4E-12 T 06-07-2017 IPR011989 Armadillo-like helical LK06_RS28005 763dc839a4f73fa9972e480f66d3c994 190 Gene3D G3DSA:1.25.10.10 125 187 7.4E-12 T 06-07-2017 IPR011989 Armadillo-like helical LK06_RS23170 7c4eb0e0ec53b628835cc878f70479a3 405 Pfam PF01548 Transposase 11 164 2.0E-42 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS23170 7c4eb0e0ec53b628835cc878f70479a3 405 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 358 1.4E-24 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 LK06_RS00485 cb4f6213945c0a12c9c1db27949dd18c 582 Gene3D G3DSA:3.20.20.80 45 315 5.8E-9 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS00485 cb4f6213945c0a12c9c1db27949dd18c 582 SUPERFAMILY SSF51445 42 314 1.99E-18 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS00485 cb4f6213945c0a12c9c1db27949dd18c 582 Gene3D G3DSA:2.60.120.260 459 579 3.0E-5 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS00485 cb4f6213945c0a12c9c1db27949dd18c 582 Pfam PF02018 Carbohydrate binding domain 457 567 2.2E-9 T 06-07-2017 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 LK06_RS00485 cb4f6213945c0a12c9c1db27949dd18c 582 SUPERFAMILY SSF49785 458 581 7.44E-6 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS00485 cb4f6213945c0a12c9c1db27949dd18c 582 Pfam PF00704 Glycosyl hydrolases family 18 44 241 6.7E-12 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 LK06_RS27795 2d55f5f6805ffb6bdabeee3b2c63c386 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 4.7E-22 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS27795 2d55f5f6805ffb6bdabeee3b2c63c386 259 Gene3D G3DSA:3.60.10.10 1 257 8.4E-76 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS27795 2d55f5f6805ffb6bdabeee3b2c63c386 259 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 257 4.2E-82 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 LK06_RS27795 2d55f5f6805ffb6bdabeee3b2c63c386 259 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 2.5E-60 T 06-07-2017 LK06_RS27795 2d55f5f6805ffb6bdabeee3b2c63c386 259 SUPERFAMILY SSF56219 1 257 2.22E-69 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS19785 b180eb8f89d4d10675455f72a0af03db 165 Gene3D G3DSA:1.10.10.10 9 160 4.2E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19785 b180eb8f89d4d10675455f72a0af03db 165 SMART SM00347 43 146 1.4E-21 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19785 b180eb8f89d4d10675455f72a0af03db 165 Pfam PF01047 MarR family 54 111 2.8E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19785 b180eb8f89d4d10675455f72a0af03db 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 1.6E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19785 b180eb8f89d4d10675455f72a0af03db 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 1.6E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19785 b180eb8f89d4d10675455f72a0af03db 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 1.6E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19785 b180eb8f89d4d10675455f72a0af03db 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 1.6E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19785 b180eb8f89d4d10675455f72a0af03db 165 SUPERFAMILY SSF46785 11 160 7.66E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19785 b180eb8f89d4d10675455f72a0af03db 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site LK06_RS26840 dd0b640af05a0fc0a866f607234e63c0 330 Pfam PF01636 Phosphotransferase enzyme family 33 254 7.8E-17 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS26840 dd0b640af05a0fc0a866f607234e63c0 330 Gene3D G3DSA:3.90.1200.10 102 252 2.2E-14 T 06-07-2017 LK06_RS26840 dd0b640af05a0fc0a866f607234e63c0 330 SUPERFAMILY SSF56112 33 267 5.78E-19 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS06460 90191646cd9fd3297744ce929f664a89 422 Gene3D G3DSA:3.90.1150.10 298 416 4.2E-30 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS06460 90191646cd9fd3297744ce929f664a89 422 Pfam PF00266 Aminotransferase class-V 35 410 1.6E-153 T 06-07-2017 IPR000192 Aminotransferase class V domain LK06_RS06460 90191646cd9fd3297744ce929f664a89 422 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 16 422 3.9E-187 T 06-07-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 LK06_RS06460 90191646cd9fd3297744ce929f664a89 422 PIRSF PIRSF005572 32 418 1.4E-47 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 LK06_RS06460 90191646cd9fd3297744ce929f664a89 422 SUPERFAMILY SSF53383 13 417 2.33E-126 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS06460 90191646cd9fd3297744ce929f664a89 422 Gene3D G3DSA:3.40.640.10 46 297 9.0E-89 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS25375 174f683d273bed55a39500f9f56ee14a 466 Pfam PF05193 Peptidase M16 inactive domain 190 378 5.8E-22 T 06-07-2017 IPR007863 Peptidase M16, C-terminal LK06_RS25375 174f683d273bed55a39500f9f56ee14a 466 SUPERFAMILY SSF63411 13 245 7.7E-39 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LK06_RS25375 174f683d273bed55a39500f9f56ee14a 466 Gene3D G3DSA:3.30.830.10 253 446 1.6E-10 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 LK06_RS25375 174f683d273bed55a39500f9f56ee14a 466 SUPERFAMILY SSF63411 253 455 8.68E-20 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LK06_RS25375 174f683d273bed55a39500f9f56ee14a 466 Pfam PF00675 Insulinase (Peptidase family M16) 41 167 6.7E-11 T 06-07-2017 IPR011765 Peptidase M16, N-terminal LK06_RS25375 174f683d273bed55a39500f9f56ee14a 466 Gene3D G3DSA:3.30.830.10 27 237 2.7E-32 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 Pfam PF05199 GMC oxidoreductase 363 501 6.9E-40 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 Pfam PF00732 GMC oxidoreductase 5 278 6.1E-72 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 Gene3D G3DSA:3.50.50.60 170 296 1.4E-113 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 Gene3D G3DSA:3.50.50.60 3 126 1.4E-113 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 Gene3D G3DSA:3.50.50.60 444 507 1.4E-113 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 237 251 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 SUPERFAMILY SSF54373 274 451 1.67E-35 T 06-07-2017 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 PIRSF PIRSF000137 2 508 3.5E-134 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 SUPERFAMILY SSF51905 3 271 5.34E-75 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27640 6201a09d589d26e3f01c2d8e8a38eb87 508 SUPERFAMILY SSF51905 450 507 5.34E-75 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09310 dc5e922ebae4b939783b04d1fa1c5be2 138 SUPERFAMILY SSF46785 10 131 1.24E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09310 dc5e922ebae4b939783b04d1fa1c5be2 138 Gene3D G3DSA:1.10.10.10 11 78 5.7E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09310 dc5e922ebae4b939783b04d1fa1c5be2 138 Pfam PF01475 Ferric uptake regulator family 11 126 1.6E-32 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 LK06_RS26415 48c8377c4370fc3fc142a61093785b56 219 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 219 18.906 T 06-07-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 LK06_RS26415 48c8377c4370fc3fc142a61093785b56 219 SUPERFAMILY SSF52218 4 162 3.1E-29 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS26415 48c8377c4370fc3fc142a61093785b56 219 Pfam PF02525 Flavodoxin-like fold 3 161 1.8E-21 T 06-07-2017 IPR003680 Flavodoxin-like fold LK06_RS26415 48c8377c4370fc3fc142a61093785b56 219 Gene3D G3DSA:3.40.50.360 1 199 1.0E-33 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS15990 a77e5073281216325ae69f72bd31a813 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 06-07-2017 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 LK06_RS15990 a77e5073281216325ae69f72bd31a813 96 SUPERFAMILY SSF54995 1 94 1.44E-32 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS15990 a77e5073281216325ae69f72bd31a813 96 Gene3D G3DSA:3.30.70.60 1 94 4.3E-35 T 06-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 LK06_RS15990 a77e5073281216325ae69f72bd31a813 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 6.9E-26 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS15990 a77e5073281216325ae69f72bd31a813 96 Pfam PF01250 Ribosomal protein S6 3 92 6.6E-29 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS15990 a77e5073281216325ae69f72bd31a813 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 22.46 T 06-07-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 LK06_RS24020 b51d133494941758907fe8f0eb15bafc 347 Gene3D G3DSA:3.40.718.10 5 333 1.3E-114 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LK06_RS24020 b51d133494941758907fe8f0eb15bafc 347 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 326 3.0E-90 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LK06_RS24020 b51d133494941758907fe8f0eb15bafc 347 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 LK06_RS24020 b51d133494941758907fe8f0eb15bafc 347 SMART SM01329 6 341 2.4E-163 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LK06_RS24020 b51d133494941758907fe8f0eb15bafc 347 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 5 345 59.804 T 06-07-2017 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 LK06_RS24020 b51d133494941758907fe8f0eb15bafc 347 SUPERFAMILY SSF53659 4 344 6.34E-109 T 06-07-2017 LK06_RS09155 cccb79cb6cac570e1dedca3de2bf1cca 485 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 343 364 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LK06_RS09155 cccb79cb6cac570e1dedca3de2bf1cca 485 Gene3D G3DSA:3.30.420.40 245 472 2.1E-23 T 06-07-2017 LK06_RS09155 cccb79cb6cac570e1dedca3de2bf1cca 485 Gene3D G3DSA:3.30.420.40 3 239 1.5E-33 T 06-07-2017 LK06_RS09155 cccb79cb6cac570e1dedca3de2bf1cca 485 PIRSF PIRSF000538 1 472 2.9E-61 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LK06_RS09155 cccb79cb6cac570e1dedca3de2bf1cca 485 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 238 2.9E-34 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 LK06_RS09155 cccb79cb6cac570e1dedca3de2bf1cca 485 SUPERFAMILY SSF53067 245 462 4.86E-35 T 06-07-2017 LK06_RS09155 cccb79cb6cac570e1dedca3de2bf1cca 485 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 247 431 1.5E-19 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 LK06_RS09155 cccb79cb6cac570e1dedca3de2bf1cca 485 SUPERFAMILY SSF53067 4 241 1.23E-33 T 06-07-2017 LK06_RS32085 373b0579fda98451a5056caf2c609fe8 490 Pfam PF13560 Helix-turn-helix domain 60 116 1.9E-11 T 06-07-2017 LK06_RS32085 373b0579fda98451a5056caf2c609fe8 490 Gene3D G3DSA:1.10.260.40 57 116 2.7E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS32085 373b0579fda98451a5056caf2c609fe8 490 SUPERFAMILY SSF47413 59 119 7.24E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS32085 373b0579fda98451a5056caf2c609fe8 490 SUPERFAMILY SSF52540 134 361 1.24E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32085 373b0579fda98451a5056caf2c609fe8 490 SMART SM00530 63 119 5.9E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS32085 373b0579fda98451a5056caf2c609fe8 490 Pfam PF13191 AAA ATPase domain 142 206 1.1E-8 T 06-07-2017 LK06_RS32085 373b0579fda98451a5056caf2c609fe8 490 Gene3D G3DSA:3.40.50.300 141 187 9.4E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07805 74f99efe825a963330ebaf6ada762446 207 SUPERFAMILY SSF48008 78 196 4.97E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS07805 74f99efe825a963330ebaf6ada762446 207 Gene3D G3DSA:1.20.120.530 74 199 2.0E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS07805 74f99efe825a963330ebaf6ada762446 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 5.6E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS07805 74f99efe825a963330ebaf6ada762446 207 Gene3D G3DSA:1.10.10.10 7 72 9.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS07805 74f99efe825a963330ebaf6ada762446 207 SMART SM00895 81 202 2.7E-10 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS07805 74f99efe825a963330ebaf6ada762446 207 Pfam PF07729 FCD domain 82 199 5.4E-17 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS07805 74f99efe825a963330ebaf6ada762446 207 SMART SM00345 13 71 8.0E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS07805 74f99efe825a963330ebaf6ada762446 207 SUPERFAMILY SSF46785 8 100 1.45E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14025 a6511267ddf5bdcf50a2f9b49745dc1a 830 Gene3D G3DSA:3.40.50.300 75 289 1.9E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14025 a6511267ddf5bdcf50a2f9b49745dc1a 830 Pfam PF00271 Helicase conserved C-terminal domain 346 456 8.2E-11 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS14025 a6511267ddf5bdcf50a2f9b49745dc1a 830 SUPERFAMILY SSF52540 160 301 8.2E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14025 a6511267ddf5bdcf50a2f9b49745dc1a 830 SUPERFAMILY SSF52540 338 473 8.2E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14025 a6511267ddf5bdcf50a2f9b49745dc1a 830 Pfam PF09369 Domain of unknown function (DUF1998) 717 796 7.6E-19 T 06-07-2017 IPR018973 DEAD/DEAH-box helicase, putative LK06_RS14025 a6511267ddf5bdcf50a2f9b49745dc1a 830 Pfam PF00270 DEAD/DEAH box helicase 94 287 1.1E-24 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS14025 a6511267ddf5bdcf50a2f9b49745dc1a 830 SMART SM00490 375 456 1.8E-16 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS14025 a6511267ddf5bdcf50a2f9b49745dc1a 830 Gene3D G3DSA:3.40.50.300 341 484 2.4E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14025 a6511267ddf5bdcf50a2f9b49745dc1a 830 SMART SM00487 87 315 3.1E-28 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS14025 a6511267ddf5bdcf50a2f9b49745dc1a 830 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 55 822 0.0 T 06-07-2017 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria LK06_RS24895 e519bbdff85c704d4051b49402a80e36 150 SUPERFAMILY SSF48452 97 144 9.49E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS24895 e519bbdff85c704d4051b49402a80e36 150 Gene3D G3DSA:1.25.40.10 108 144 3.5E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 SMART SM00738 94 202 3.2E-44 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 Gene3D G3DSA:2.30.30.30 229 283 8.5E-26 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 PRINTS PR00338 Transcription termination factor NUSG signature 242 257 3.5E-18 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 PRINTS PR00338 Transcription termination factor NUSG signature 260 276 3.5E-18 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 PRINTS PR00338 Transcription termination factor NUSG signature 149 161 3.5E-18 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 SUPERFAMILY SSF82679 96 202 7.32E-35 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 SUPERFAMILY SSF50104 229 283 1.73E-15 T 06-07-2017 IPR008991 Translation protein SH3-like domain LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 ProSitePatterns PS01014 Transcription termination factor nusG signature. 267 276 - T 06-07-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 97 283 2.0E-54 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 Gene3D G3DSA:3.30.70.940 96 204 1.3E-41 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 94 284 22.747 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 Pfam PF02357 Transcription termination factor nusG 96 198 8.6E-23 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 LK06_RS12460 4fc7b55c8b54710efcf749e074f98f60 284 SMART SM00739 230 257 2.5E-5 T 06-07-2017 IPR005824 KOW LK06_RS02960 df26efce4be647dedcf6f42119bbc7f5 387 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 267 355 4.5E-10 T 06-07-2017 IPR026843 Nuclease SbcCD subunit D, C-terminal domain LK06_RS02960 df26efce4be647dedcf6f42119bbc7f5 387 Gene3D G3DSA:3.60.21.10 1 264 1.7E-71 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS02960 df26efce4be647dedcf6f42119bbc7f5 387 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 244 1.0E-54 T 06-07-2017 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 LK06_RS02960 df26efce4be647dedcf6f42119bbc7f5 387 SUPERFAMILY SSF56300 1 306 1.65E-56 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS02960 df26efce4be647dedcf6f42119bbc7f5 387 Pfam PF00149 Calcineurin-like phosphoesterase 1 218 8.6E-12 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 LK06_RS05005 2640f95fa30dd289d73ab93bcc392f5b 352 Gene3D G3DSA:1.10.260.40 22 75 6.0E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS05005 2640f95fa30dd289d73ab93bcc392f5b 352 SMART SM00354 21 93 1.3E-22 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS05005 2640f95fa30dd289d73ab93bcc392f5b 352 Gene3D G3DSA:3.40.50.2300 194 329 3.8E-34 T 06-07-2017 LK06_RS05005 2640f95fa30dd289d73ab93bcc392f5b 352 Gene3D G3DSA:3.40.50.2300 76 193 7.1E-24 T 06-07-2017 LK06_RS05005 2640f95fa30dd289d73ab93bcc392f5b 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 25 70 8.9E-15 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS05005 2640f95fa30dd289d73ab93bcc392f5b 352 SUPERFAMILY SSF47413 21 81 4.08E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS05005 2640f95fa30dd289d73ab93bcc392f5b 352 Pfam PF13377 Periplasmic binding protein-like domain 189 346 1.3E-30 T 06-07-2017 LK06_RS05005 2640f95fa30dd289d73ab93bcc392f5b 352 SUPERFAMILY SSF53822 80 332 1.22E-45 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS04875 63cc625e8bc1940d8a5b61aee9869e7e 245 SMART SM00345 30 91 2.2E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS04875 63cc625e8bc1940d8a5b61aee9869e7e 245 Pfam PF07729 FCD domain 114 233 2.6E-20 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS04875 63cc625e8bc1940d8a5b61aee9869e7e 245 Gene3D G3DSA:1.10.10.10 27 96 1.9E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04875 63cc625e8bc1940d8a5b61aee9869e7e 245 SUPERFAMILY SSF46785 22 95 3.01E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04875 63cc625e8bc1940d8a5b61aee9869e7e 245 SUPERFAMILY SSF48008 111 243 2.35E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS04875 63cc625e8bc1940d8a5b61aee9869e7e 245 Gene3D G3DSA:1.20.120.530 111 243 6.5E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS04875 63cc625e8bc1940d8a5b61aee9869e7e 245 SMART SM00895 114 235 4.8E-18 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS04875 63cc625e8bc1940d8a5b61aee9869e7e 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 91 1.4E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS04875 63cc625e8bc1940d8a5b61aee9869e7e 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 2.2E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS04875 63cc625e8bc1940d8a5b61aee9869e7e 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 2.2E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS12230 976cc2260ed721029e10379bb820e31c 127 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 15 127 3.9E-40 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12230 976cc2260ed721029e10379bb820e31c 127 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 13 127 27.23 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12230 976cc2260ed721029e10379bb820e31c 127 Gene3D G3DSA:3.30.420.100 31 127 2.8E-39 T 06-07-2017 LK06_RS12230 976cc2260ed721029e10379bb820e31c 127 SUPERFAMILY SSF53137 14 125 1.05E-47 T 06-07-2017 LK06_RS12230 976cc2260ed721029e10379bb820e31c 127 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 13 127 6.0E-50 T 06-07-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF51412 20 212 3.66E-17 T 06-07-2017 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 865 881 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Gene3D G3DSA:1.10.1200.10 1690 1764 3.8E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF53901 689 805 8.8E-78 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF53901 848 1073 8.8E-78 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF53901 1106 1124 8.8E-78 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Gene3D G3DSA:3.40.47.10 966 1127 3.3E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF55048 1363 1428 2.35E-13 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 691 952 1.5E-67 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 960 1077 7.3E-37 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF51735 1866 2038 3.94E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF51735 2146 2329 6.22E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF51735 2064 2106 6.22E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Pfam PF03060 Nitronate monooxygenase 312 578 1.1E-11 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Gene3D G3DSA:3.30.70.250 1362 1421 3.0E-13 T 06-07-2017 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Pfam PF00550 Phosphopantetheine attachment site 1695 1761 5.2E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF52151 1430 1531 1.2E-49 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF52151 1233 1362 1.2E-49 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF51412 316 584 2.2E-16 T 06-07-2017 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Pfam PF08659 KR domain 2066 2288 2.9E-31 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Gene3D G3DSA:3.40.366.10 1428 1537 8.2E-49 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Gene3D G3DSA:3.40.366.10 1232 1356 8.2E-49 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Gene3D G3DSA:3.20.20.70 21 209 8.1E-18 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Gene3D G3DSA:3.20.20.70 313 587 5.8E-18 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1237 1537 1.0E-25 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Gene3D G3DSA:3.40.50.720 2144 2324 2.1E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Gene3D G3DSA:3.40.50.720 2064 2098 2.1E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2065 2290 1.2E-19 T 06-07-2017 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SUPERFAMILY SSF47336 1688 1779 6.91E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Pfam PF00698 Acyl transferase domain 1237 1520 6.9E-32 T 06-07-2017 IPR014043 Acyl transferase LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1085 1167 5.9E-8 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 SMART SM00825 Beta-ketoacyl synthase 692 1130 2.8E-114 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS03050 9c125a58cb11a1408156fc6e12a4be4f 2343 Gene3D G3DSA:3.40.47.10 691 965 1.8E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS20375 b30ed1cc09ae5aca0c945cedc380ca54 225 SUPERFAMILY SSF81995 9 82 4.45E-5 T 06-07-2017 LK06_RS30380 89721966396803ec2e76c56b085b749e 72 SUPERFAMILY SSF48264 1 72 4.85E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS30380 89721966396803ec2e76c56b085b749e 72 Gene3D G3DSA:1.10.630.10 1 72 3.5E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS28655 3997012cc224c7bd6f277957fb5fc35f 546 SUPERFAMILY SSF52540 5 229 7.27E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28655 3997012cc224c7bd6f277957fb5fc35f 546 SUPERFAMILY SSF52540 358 543 4.43E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28655 3997012cc224c7bd6f277957fb5fc35f 546 Pfam PF00005 ABC transporter 368 496 1.6E-14 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS28655 3997012cc224c7bd6f277957fb5fc35f 546 Pfam PF00005 ABC transporter 22 187 3.1E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS28655 3997012cc224c7bd6f277957fb5fc35f 546 SMART SM00382 29 232 1.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS28655 3997012cc224c7bd6f277957fb5fc35f 546 SMART SM00382 375 542 1.0E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS28655 3997012cc224c7bd6f277957fb5fc35f 546 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS28655 3997012cc224c7bd6f277957fb5fc35f 546 Gene3D G3DSA:3.40.50.300 369 545 5.5E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28655 3997012cc224c7bd6f277957fb5fc35f 546 Gene3D G3DSA:3.40.50.300 136 278 2.3E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28655 3997012cc224c7bd6f277957fb5fc35f 546 Gene3D G3DSA:3.40.50.300 7 103 2.3E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17510 410870bdb4aff108157b3390bcec076e 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 1.3E-112 T 06-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 LK06_RS17510 410870bdb4aff108157b3390bcec076e 258 SUPERFAMILY SSF52540 5 246 9.82E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17510 410870bdb4aff108157b3390bcec076e 258 SMART SM00382 29 229 1.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS17510 410870bdb4aff108157b3390bcec076e 258 Pfam PF00005 ABC transporter 21 176 3.9E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS17510 410870bdb4aff108157b3390bcec076e 258 Gene3D G3DSA:3.40.50.300 3 250 2.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17510 410870bdb4aff108157b3390bcec076e 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS06835 dabb554f2014fbb25c6fdac9992ecf3f 126 Gene3D G3DSA:1.25.40.10 19 115 3.2E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS06835 dabb554f2014fbb25c6fdac9992ecf3f 126 Pfam PF07719 Tetratricopeptide repeat 83 115 3.3E-8 T 06-07-2017 IPR013105 Tetratricopeptide repeat 2 LK06_RS06835 dabb554f2014fbb25c6fdac9992ecf3f 126 Pfam PF14559 Tetratricopeptide repeat 25 82 1.3E-5 T 06-07-2017 LK06_RS06835 dabb554f2014fbb25c6fdac9992ecf3f 126 SMART SM00028 83 116 4.0E-4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS06835 dabb554f2014fbb25c6fdac9992ecf3f 126 SMART SM00028 49 82 83.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS06835 dabb554f2014fbb25c6fdac9992ecf3f 126 SUPERFAMILY SSF48452 12 118 5.55E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 Pfam PF13307 Helicase C-terminal domain 471 630 1.1E-27 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 SMART SM00487 17 288 5.1E-4 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 SMART SM00491 488 618 1.1E-41 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 Gene3D G3DSA:3.40.50.300 461 612 2.2E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 SUPERFAMILY SSF52540 392 406 8.28E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 SUPERFAMILY SSF52540 189 264 8.28E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 SUPERFAMILY SSF52540 445 601 8.28E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 SUPERFAMILY SSF52540 35 85 8.28E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 Gene3D G3DSA:3.40.50.300 189 261 5.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 Gene3D G3DSA:3.40.50.300 394 402 5.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 Gene3D G3DSA:3.40.50.300 135 136 5.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25190 73dec0c44a65f74bc74f495423d9e73b 658 Gene3D G3DSA:3.40.50.300 30 83 5.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10165 5744484ad31ea5e7ae0276c101df5cb4 447 SMART SM00327 59 236 1.9E-11 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS10165 5744484ad31ea5e7ae0276c101df5cb4 447 SUPERFAMILY SSF53300 58 239 2.07E-21 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS10165 5744484ad31ea5e7ae0276c101df5cb4 447 Pfam PF13519 von Willebrand factor type A domain 63 171 2.0E-9 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS10165 5744484ad31ea5e7ae0276c101df5cb4 447 Gene3D G3DSA:3.40.50.410 60 232 1.4E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS07010 0a6ce24f9e8cff78ed352501705fc460 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.1E-19 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS07010 0a6ce24f9e8cff78ed352501705fc460 203 SUPERFAMILY SSF46689 12 90 4.82E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS07010 0a6ce24f9e8cff78ed352501705fc460 203 Gene3D G3DSA:1.10.10.60 12 64 2.7E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS07010 0a6ce24f9e8cff78ed352501705fc460 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.3E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS07010 0a6ce24f9e8cff78ed352501705fc460 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.3E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS07010 0a6ce24f9e8cff78ed352501705fc460 203 SUPERFAMILY SSF48498 87 200 3.25E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS07010 0a6ce24f9e8cff78ed352501705fc460 203 Gene3D G3DSA:1.10.357.10 65 202 5.4E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS15285 5ab5c6da48c4189d9236bbea550a5101 567 SMART SM00327 381 557 4.7E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS15285 5ab5c6da48c4189d9236bbea550a5101 567 SUPERFAMILY SSF53300 382 543 1.52E-14 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS15285 5ab5c6da48c4189d9236bbea550a5101 567 Pfam PF10138 vWA found in TerF C terminus 381 563 1.5E-35 T 06-07-2017 IPR019303 vWA found in TerF C terminus LK06_RS15285 5ab5c6da48c4189d9236bbea550a5101 567 Gene3D G3DSA:3.40.50.410 383 536 5.2E-9 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 Gene3D G3DSA:3.40.190.10 2 108 7.8E-38 T 06-07-2017 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 SUPERFAMILY SSF53850 5 219 2.62E-64 T 06-07-2017 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 214 1.8E-66 T 06-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 SUPERFAMILY SSF54782 222 316 1.05E-17 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 PRINTS PR00151 Porphobilinogen deaminase signature 145 162 2.1E-18 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 2.1E-18 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 PRINTS PR00151 Porphobilinogen deaminase signature 232 249 2.1E-18 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 2.1E-18 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 229 306 4.2E-16 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 Gene3D G3DSA:3.30.160.40 223 315 3.6E-21 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 PIRSF PIRSF001438 1 319 1.6E-107 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 233 249 - T 06-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 308 9.4E-85 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 308 34.968 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13420 da79f890df5216407f702eaa353c93ca 319 Gene3D G3DSA:3.40.190.10 109 201 1.2E-31 T 06-07-2017 LK06_RS30630 740dc2c873058e7a8949ef7d276f3272 656 SUPERFAMILY SSF55846 274 436 2.62E-36 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS30630 740dc2c873058e7a8949ef7d276f3272 656 Gene3D G3DSA:3.40.80.10 285 435 8.2E-34 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS30630 740dc2c873058e7a8949ef7d276f3272 656 SMART SM00644 286 423 1.1E-35 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS30630 740dc2c873058e7a8949ef7d276f3272 656 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 295 424 7.1E-18 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS30630 740dc2c873058e7a8949ef7d276f3272 656 Gene3D G3DSA:1.10.530.10 51 110 3.2E-4 T 06-07-2017 LK06_RS30630 740dc2c873058e7a8949ef7d276f3272 656 Gene3D G3DSA:1.10.530.10 156 196 3.2E-4 T 06-07-2017 LK06_RS09235 59c511d323ac7d68f9b0a551091b5d5c 117 SUPERFAMILY SSF50022 19 114 1.3E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS09235 59c511d323ac7d68f9b0a551091b5d5c 117 Pfam PF13806 Rieske-like [2Fe-2S] domain 20 114 7.4E-34 T 06-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 LK06_RS09235 59c511d323ac7d68f9b0a551091b5d5c 117 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 20 115 1.4E-27 T 06-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 LK06_RS09235 59c511d323ac7d68f9b0a551091b5d5c 117 Gene3D G3DSA:2.102.10.10 18 114 1.7E-35 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS32300 6882be476729de222479620c25c29d02 113 Pfam PF03551 Transcriptional regulator PadR-like family 16 88 9.0E-20 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal LK06_RS32300 6882be476729de222479620c25c29d02 113 Gene3D G3DSA:1.10.10.10 13 98 1.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32300 6882be476729de222479620c25c29d02 113 SUPERFAMILY SSF46785 13 100 1.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 713 727 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 170 184 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1086 12.999 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 340 1.1E-66 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 677 879 9.1E-34 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Gene3D G3DSA:3.40.50.1380 957 1096 1.4E-40 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 431 547 1.3E-36 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 SUPERFAMILY SSF48108 401 553 5.23E-46 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Pfam PF02142 MGS-like domain 975 1065 4.9E-21 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 303 310 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Gene3D G3DSA:3.40.50.20 3 107 2.0E-42 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 SUPERFAMILY SSF56059 128 406 3.89E-101 T 06-07-2017 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 SUPERFAMILY SSF56059 677 951 5.66E-90 T 06-07-2017 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Gene3D G3DSA:3.30.470.20 749 952 5.7E-62 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Gene3D G3DSA:3.30.470.20 206 405 1.9E-77 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 SUPERFAMILY SSF52440 2 127 1.87E-46 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 842 849 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 SUPERFAMILY SSF52440 557 678 7.63E-43 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1074 0.0 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 SUPERFAMILY SSF52335 960 1094 8.24E-34 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Gene3D G3DSA:3.30.1490.20 690 748 4.4E-25 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Gene3D G3DSA:3.30.1490.20 148 205 1.4E-19 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 SMART SM00851 974 1065 9.7E-28 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 SMART SM01096 426 547 6.3E-61 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Gene3D G3DSA:3.40.50.20 539 665 3.8E-56 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 Gene3D G3DSA:1.10.1030.10 406 538 8.8E-45 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 245 262 2.2E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 303 332 2.2E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 385 403 2.2E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.2E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 174 186 2.2E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 210 229 2.2E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04110 3ea44b2a5e359ecdc1c5ab7d833b5df2 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.2E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS30730 fea33e29ad2f49941c8a9c8beb60d11f 308 Gene3D G3DSA:3.30.2010.10 121 182 3.0E-11 T 06-07-2017 LK06_RS30730 fea33e29ad2f49941c8a9c8beb60d11f 308 Pfam PF01435 Peptidase family M48 125 186 6.5E-10 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 Gene3D G3DSA:3.40.192.10 17 158 8.0E-64 T 06-07-2017 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 PIRSF PIRSF000188 12 371 5.8E-142 T 06-07-2017 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 221 313 1.0E-7 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 SMART SM00839 155 369 1.3E-41 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 SUPERFAMILY SSF53223 22 155 2.11E-44 T 06-07-2017 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 143 165 2.1E-20 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 304 315 2.1E-20 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 187 207 2.1E-20 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 77 91 2.1E-20 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 30 141 2.0E-24 T 06-07-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 85 98 - T 06-07-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 SUPERFAMILY SSF51735 152 366 3.27E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS17055 5e34525d474129c19859183a0fe8ab3b 371 Gene3D G3DSA:3.40.50.720 159 354 4.9E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00770 2b515dcc2d42c1f2940d68c577c49330 265 Pfam PF04672 S-adenosyl methyltransferase 8 265 9.3E-104 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS00770 2b515dcc2d42c1f2940d68c577c49330 265 SUPERFAMILY SSF53335 16 252 3.57E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS00770 2b515dcc2d42c1f2940d68c577c49330 265 Gene3D G3DSA:3.40.50.150 5 265 2.5E-107 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS00770 2b515dcc2d42c1f2940d68c577c49330 265 PIRSF PIRSF017393 1 265 1.9E-91 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS09220 1d76990334642f2844c56e38d1960b83 208 SUPERFAMILY SSF63817 56 204 1.67E-13 T 06-07-2017 IPR023365 Sortase domain LK06_RS09220 1d76990334642f2844c56e38d1960b83 208 Pfam PF04203 Sortase family 65 204 8.0E-17 T 06-07-2017 IPR005754 Sortase family LK06_RS09220 1d76990334642f2844c56e38d1960b83 208 Gene3D G3DSA:2.40.260.10 64 186 1.1E-5 T 06-07-2017 IPR023365 Sortase domain LK06_RS25690 a2a7a4c93c8cd627732b83fac7c21446 265 SUPERFAMILY SSF46894 198 263 7.82E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS25690 a2a7a4c93c8cd627732b83fac7c21446 265 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 217 8.3E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS25690 a2a7a4c93c8cd627732b83fac7c21446 265 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 217 233 8.3E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS25690 a2a7a4c93c8cd627732b83fac7c21446 265 Gene3D G3DSA:1.10.10.10 194 262 1.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25690 a2a7a4c93c8cd627732b83fac7c21446 265 SMART SM00421 200 257 2.3E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS25690 a2a7a4c93c8cd627732b83fac7c21446 265 Pfam PF00196 Bacterial regulatory proteins, luxR family 202 256 3.2E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20510 63561a881ee0638e6965b3c983fce0e2 462 Pfam PF17199 Protein of unknown function (DUF5136) 1 28 8.9E-20 T 06-07-2017 LK06_RS20510 63561a881ee0638e6965b3c983fce0e2 462 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 125 347 5.2E-31 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 LK06_RS20510 63561a881ee0638e6965b3c983fce0e2 462 Gene3D G3DSA:3.40.710.10 120 369 7.6E-64 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS20510 63561a881ee0638e6965b3c983fce0e2 462 SUPERFAMILY SSF56601 126 369 1.69E-43 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS20510 63561a881ee0638e6965b3c983fce0e2 462 SUPERFAMILY SSF56601 60 87 1.69E-43 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 SUPERFAMILY SSF88946 87 182 1.23E-32 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 SUPERFAMILY SSF88659 186 260 1.35E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 107 329 1.2E-95 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 Gene3D G3DSA:1.10.10.10 270 329 4.9E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 PRINTS PR00046 Major sigma-70 factor signature 282 294 1.3E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 PRINTS PR00046 Major sigma-70 factor signature 137 150 1.3E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 PRINTS PR00046 Major sigma-70 factor signature 314 325 1.3E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 PRINTS PR00046 Major sigma-70 factor signature 161 169 1.3E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 PRINTS PR00046 Major sigma-70 factor signature 299 314 1.3E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 SUPERFAMILY SSF88659 249 329 8.6E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 Gene3D G3DSA:1.10.10.10 181 236 8.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 109 329 7.4E-39 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 Gene3D G3DSA:1.10.601.10 100 180 1.5E-27 T 06-07-2017 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 Pfam PF04542 Sigma-70 region 2 113 182 2.2E-21 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 Pfam PF04545 Sigma-70, region 4 278 327 2.4E-16 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22475 ae4de7069ad75a0c2bf29daf43fe79f8 333 Pfam PF04539 Sigma-70 region 3 194 252 2.0E-14 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS06480 4992c6fd627a5040b59472b96c90a32d 473 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 2.0E-76 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 LK06_RS06480 4992c6fd627a5040b59472b96c90a32d 473 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 464 7.8E-222 T 06-07-2017 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 LK06_RS06480 4992c6fd627a5040b59472b96c90a32d 473 SUPERFAMILY SSF101960 39 470 1.1E-141 T 06-07-2017 LK06_RS05100 e58cb6d89c4f1a8f105ff4d1caa9da71 254 Gene3D G3DSA:1.10.10.10 4 74 2.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05100 e58cb6d89c4f1a8f105ff4d1caa9da71 254 SMART SM00346 5 95 2.3E-35 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS05100 e58cb6d89c4f1a8f105ff4d1caa9da71 254 Pfam PF09339 IclR helix-turn-helix domain 7 58 3.2E-17 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS05100 e58cb6d89c4f1a8f105ff4d1caa9da71 254 SUPERFAMILY SSF55781 71 250 5.62E-37 T 06-07-2017 IPR029016 GAF domain-like LK06_RS05100 e58cb6d89c4f1a8f105ff4d1caa9da71 254 Pfam PF01614 Bacterial transcriptional regulator 123 247 5.1E-34 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal LK06_RS05100 e58cb6d89c4f1a8f105ff4d1caa9da71 254 SUPERFAMILY SSF46785 5 77 6.12E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05100 e58cb6d89c4f1a8f105ff4d1caa9da71 254 Gene3D G3DSA:3.30.450.40 75 250 5.7E-43 T 06-07-2017 IPR029016 GAF domain-like LK06_RS31115 4536109d0a8e93d382ae08323092876f 298 Gene3D G3DSA:3.90.1200.10 96 260 2.8E-31 T 06-07-2017 LK06_RS31115 4536109d0a8e93d382ae08323092876f 298 Pfam PF01636 Phosphotransferase enzyme family 23 251 2.8E-33 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS31115 4536109d0a8e93d382ae08323092876f 298 SUPERFAMILY SSF56112 12 261 4.21E-43 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS12315 01bf19ce889c50d5d373b125cca6f0f9 214 Gene3D G3DSA:4.10.960.10 80 161 9.2E-34 T 06-07-2017 LK06_RS12315 01bf19ce889c50d5d373b125cca6f0f9 214 SUPERFAMILY SSF50447 5 212 9.71E-82 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS12315 01bf19ce889c50d5d373b125cca6f0f9 214 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 5 211 40.426 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12315 01bf19ce889c50d5d373b125cca6f0f9 214 Pfam PF00297 Ribosomal protein L3 98 186 7.8E-15 T 06-07-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12315 01bf19ce889c50d5d373b125cca6f0f9 214 ProSitePatterns PS00474 Ribosomal protein L3 signature. 105 128 - T 06-07-2017 IPR019926 Ribosomal protein L3, conserved site LK06_RS12315 01bf19ce889c50d5d373b125cca6f0f9 214 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 7 208 1.0E-91 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12315 01bf19ce889c50d5d373b125cca6f0f9 214 Gene3D G3DSA:2.40.30.10 7 36 6.7E-12 T 06-07-2017 LK06_RS12315 01bf19ce889c50d5d373b125cca6f0f9 214 Gene3D G3DSA:2.40.30.10 162 211 6.7E-12 T 06-07-2017 LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 5.6E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 310 5.6E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 5.6E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 Gene3D G3DSA:3.30.565.10 200 367 2.1E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 Gene3D G3DSA:1.10.287.130 142 199 2.1E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 Pfam PF00512 His Kinase A (phospho-acceptor) domain 150 214 2.6E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 SMART SM00387 259 369 2.2E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 SMART SM00388 150 214 4.5E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 SUPERFAMILY SSF47384 136 215 1.69E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 260 367 1.5E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS31440 2e793d55f8c13e3736530b0c2c5f9342 369 SUPERFAMILY SSF55874 204 367 4.06E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 Gene3D G3DSA:3.40.50.1460 5 159 2.1E-12 T 06-07-2017 IPR029030 Caspase-like domain LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 Pfam PF13087 AAA domain 973 1151 4.5E-26 T 06-07-2017 LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 Gene3D G3DSA:3.40.50.300 535 670 5.1E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 Gene3D G3DSA:3.40.50.300 891 992 5.1E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 Gene3D G3DSA:3.40.50.300 993 1149 1.1E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 SUPERFAMILY SSF52129 3 181 1.52E-12 T 06-07-2017 IPR029030 Caspase-like domain LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 Pfam PF13245 Part of AAA domain 567 628 5.1E-9 T 06-07-2017 LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 SUPERFAMILY SSF52540 973 1159 4.43E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 SUPERFAMILY SSF52540 560 626 4.43E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 SUPERFAMILY SSF52540 838 928 4.43E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 Pfam PF00656 Caspase domain 6 248 2.0E-17 T 06-07-2017 LK06_RS25715 e9d02b4b67bcb46ad6c5860f454c8150 1300 Pfam PF13086 AAA domain 878 927 4.9E-8 T 06-07-2017 LK06_RS24945 75245378cf30b66a7bbedac1b8161d98 220 Gene3D G3DSA:3.90.1150.10 100 212 3.0E-22 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS24945 75245378cf30b66a7bbedac1b8161d98 220 SUPERFAMILY SSF53383 1 90 9.46E-23 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS24945 75245378cf30b66a7bbedac1b8161d98 220 SUPERFAMILY SSF53383 101 210 4.68E-13 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS24945 75245378cf30b66a7bbedac1b8161d98 220 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 2 90 5.6E-27 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase LK06_RS24945 75245378cf30b66a7bbedac1b8161d98 220 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 101 208 5.2E-12 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase LK06_RS24945 75245378cf30b66a7bbedac1b8161d98 220 Gene3D G3DSA:3.40.640.10 1 90 1.7E-21 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS07240 14abd69d2b16eba90980fe43ffc68012 314 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 308 2.1E-86 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS07240 14abd69d2b16eba90980fe43ffc68012 314 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS07240 14abd69d2b16eba90980fe43ffc68012 314 Pfam PF00849 RNA pseudouridylate synthase 93 247 6.5E-32 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS07240 14abd69d2b16eba90980fe43ffc68012 314 SUPERFAMILY SSF55120 82 309 4.52E-70 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS07240 14abd69d2b16eba90980fe43ffc68012 314 Pfam PF01479 S4 domain 19 62 2.4E-5 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS07240 14abd69d2b16eba90980fe43ffc68012 314 Gene3D G3DSA:3.10.290.10 19 61 2.7E-8 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS07240 14abd69d2b16eba90980fe43ffc68012 314 SUPERFAMILY SSF55174 19 107 3.03E-7 T 06-07-2017 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 Gene3D G3DSA:1.10.8.60 780 857 1.7E-31 T 06-07-2017 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 Gene3D G3DSA:3.40.50.300 160 343 2.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 SMART SM00382 199 346 6.9E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 SMART SM00382 601 750 7.8E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 338 2.7E-11 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 848 3.0E-28 T 06-07-2017 IPR019489 Clp ATPase, C-terminal LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 Gene3D G3DSA:3.40.50.300 557 779 4.4E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 SUPERFAMILY SSF52540 160 549 2.76E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 5.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 5.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 5.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 5.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 SUPERFAMILY SSF81923 4 157 5.89E-29 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 SUPERFAMILY SSF52540 550 850 5.5E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 Gene3D G3DSA:1.10.1780.10 4 149 3.0E-32 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 5 855 0.0 T 06-07-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 SMART SM01086 768 857 9.7E-39 T 06-07-2017 IPR019489 Clp ATPase, C-terminal LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 Gene3D G3DSA:1.10.8.60 345 428 1.6E-34 T 06-07-2017 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 761 6.5E-53 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 19 68 3.3E-5 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS14710 83a75796b7cdd9989ae46cf73ad9e611 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 1.9E-10 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS26670 a04b44bbe0012d9e9122bc094592c779 99 Pfam PF01527 Transposase 7 76 1.7E-15 T 06-07-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 LK06_RS26670 a04b44bbe0012d9e9122bc094592c779 99 Gene3D G3DSA:1.10.10.60 10 91 2.5E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS26670 a04b44bbe0012d9e9122bc094592c779 99 SUPERFAMILY SSF46689 6 96 8.42E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 SMART SM01134 73 234 3.0E-66 T 06-07-2017 LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 SMART SM00420 6 58 2.8E-14 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 SUPERFAMILY SSF46785 5 59 1.95E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 Pfam PF00455 DeoR C terminal sensor domain 76 233 8.8E-51 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 2.2E-14 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 Gene3D G3DSA:3.40.50.1360 77 223 8.2E-13 T 06-07-2017 LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 Gene3D G3DSA:1.10.10.10 5 56 1.1E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.6E-8 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.6E-8 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS20830 c26bbe50f3132c894ca918e5bbffeeb3 315 SUPERFAMILY SSF100950 76 235 4.08E-29 T 06-07-2017 LK06_RS01610 f30fea72bafaa3beaf8ccf9ac34e921a 270 SUPERFAMILY SSF53335 16 251 1.86E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS01610 f30fea72bafaa3beaf8ccf9ac34e921a 270 Gene3D G3DSA:3.40.50.150 1 268 4.6E-107 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS01610 f30fea72bafaa3beaf8ccf9ac34e921a 270 Pfam PF04672 S-adenosyl methyltransferase 5 269 6.6E-104 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS01610 f30fea72bafaa3beaf8ccf9ac34e921a 270 PIRSF PIRSF017393 1 270 7.7E-96 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS04175 f5ec8f0e763eb639136dd18e042860d4 394 SUPERFAMILY SSF103263 3 390 1.05E-138 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LK06_RS04175 f5ec8f0e763eb639136dd18e042860d4 394 Hamap MF_00300 Chorismate synthase [aroC]. 4 376 34.585 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LK06_RS04175 f5ec8f0e763eb639136dd18e042860d4 394 ProSitePatterns PS00788 Chorismate synthase signature 2. 136 152 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LK06_RS04175 f5ec8f0e763eb639136dd18e042860d4 394 Gene3D G3DSA:3.60.150.10 4 391 1.8E-154 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LK06_RS04175 f5ec8f0e763eb639136dd18e042860d4 394 TIGRFAM TIGR00033 aroC: chorismate synthase 4 374 1.4E-140 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LK06_RS04175 f5ec8f0e763eb639136dd18e042860d4 394 ProSitePatterns PS00787 Chorismate synthase signature 1. 10 25 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LK06_RS04175 f5ec8f0e763eb639136dd18e042860d4 394 PIRSF PIRSF001456 1 387 3.6E-127 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LK06_RS04175 f5ec8f0e763eb639136dd18e042860d4 394 Pfam PF01264 Chorismate synthase 4 368 2.5E-118 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LK06_RS04175 f5ec8f0e763eb639136dd18e042860d4 394 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 Gene3D G3DSA:3.40.120.10 28 224 1.2E-56 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 SUPERFAMILY SSF55957 437 545 1.46E-18 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 321 438 1.2E-27 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 Gene3D G3DSA:3.30.310.50 467 543 1.7E-27 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 SUPERFAMILY SSF53738 306 448 2.94E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 489 537 2.8E-8 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 Gene3D G3DSA:3.40.120.10 310 444 1.2E-33 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 39 180 1.6E-34 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 3 544 3.9E-278 T 06-07-2017 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 SUPERFAMILY SSF53738 209 316 1.77E-5 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 SUPERFAMILY SSF53738 24 235 1.33E-47 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 Gene3D G3DSA:3.40.120.10 225 309 1.2E-44 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS31180 d6b8033ad953b32ce5248aecdb3ba4f2 546 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 316 6.6E-11 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS29795 2145edb05893069a0161bf40b686d300 259 Pfam PF03466 LysR substrate binding domain 22 193 2.0E-20 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS29795 2145edb05893069a0161bf40b686d300 259 SUPERFAMILY SSF53850 10 195 8.31E-21 T 06-07-2017 LK06_RS29795 2145edb05893069a0161bf40b686d300 259 Gene3D G3DSA:3.40.190.10 24 108 2.9E-12 T 06-07-2017 LK06_RS29795 2145edb05893069a0161bf40b686d300 259 Gene3D G3DSA:3.40.190.10 130 168 2.0E-4 T 06-07-2017 LK06_RS24210 f90749a1aca597e77c83fcf3d7c0e7ef 254 Pfam PF01553 Acyltransferase 30 155 1.9E-21 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS24210 f90749a1aca597e77c83fcf3d7c0e7ef 254 SUPERFAMILY SSF69593 5 227 5.36E-41 T 06-07-2017 LK06_RS24210 f90749a1aca597e77c83fcf3d7c0e7ef 254 SMART SM00563 41 159 1.0E-35 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS24210 f90749a1aca597e77c83fcf3d7c0e7ef 254 Gene3D G3DSA:3.40.1130.10 32 221 8.7E-20 T 06-07-2017 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 SUPERFAMILY SSF51905 479 535 6.79E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 SUPERFAMILY SSF51905 45 347 6.79E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 SUPERFAMILY SSF54373 351 482 7.26E-56 T 06-07-2017 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 Pfam PF00890 FAD binding domain 46 97 7.3E-5 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 141 164 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 Gene3D G3DSA:3.30.410.10 365 472 1.6E-76 T 06-07-2017 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 Gene3D G3DSA:3.30.410.10 188 246 1.6E-76 T 06-07-2017 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 Pfam PF05199 GMC oxidoreductase 477 528 6.7E-14 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 Gene3D G3DSA:3.50.50.60 45 185 1.2E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 Gene3D G3DSA:3.50.50.60 476 535 1.2E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07555 a49e91c5920216ab1add91bfb8a1cbda 540 Gene3D G3DSA:3.50.50.60 250 364 1.2E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS14595 d4a0aeba3ed14430a7842e13d82deccc 405 Hamap MF_01970 Kynureninase [kynU]. 2 403 34.365 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 LK06_RS14595 d4a0aeba3ed14430a7842e13d82deccc 405 Gene3D G3DSA:3.40.640.10 85 263 6.8E-22 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS14595 d4a0aeba3ed14430a7842e13d82deccc 405 SUPERFAMILY SSF53383 18 403 1.95E-81 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS14595 d4a0aeba3ed14430a7842e13d82deccc 405 TIGRFAM TIGR01814 kynureninase: kynureninase 19 401 1.3E-81 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 LK06_RS14595 d4a0aeba3ed14430a7842e13d82deccc 405 Pfam PF00266 Aminotransferase class-V 41 349 5.5E-18 T 06-07-2017 IPR000192 Aminotransferase class V domain LK06_RS14595 d4a0aeba3ed14430a7842e13d82deccc 405 PIRSF PIRSF038800 11 405 6.2E-132 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 LK06_RS14595 d4a0aeba3ed14430a7842e13d82deccc 405 Gene3D G3DSA:3.90.1150.10 264 403 9.7E-48 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS28855 cbdb7ea4933e3dc386b7f73e98a809fb 127 Pfam PF04237 YjbR 20 107 8.9E-19 T 06-07-2017 IPR007351 Uncharacterised protein YjbR LK06_RS28855 cbdb7ea4933e3dc386b7f73e98a809fb 127 SUPERFAMILY SSF142906 9 125 9.81E-24 T 06-07-2017 LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 SUPERFAMILY SSF47384 225 305 3.14E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 Gene3D G3DSA:3.30.565.10 343 456 5.2E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 SMART SM00388 241 307 4.5E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 Gene3D G3DSA:1.10.287.130 233 303 2.1E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 SUPERFAMILY SSF55874 313 456 2.1E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 SMART SM00387 350 457 8.5E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 1.1E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 1.1E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.1E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.1E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 306 2.4E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS01435 981a3f452c46f7479701bcc2ea256560 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 455 6.4E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS18460 eeed7e8741706ca887f7c5df4b00d6bc 127 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 06-07-2017 IPR019844 Cold-shock conserved site LK06_RS18460 eeed7e8741706ca887f7c5df4b00d6bc 127 SMART SM00357 3 65 2.7E-21 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 LK06_RS18460 eeed7e8741706ca887f7c5df4b00d6bc 127 PRINTS PR00050 Cold shock protein signature 38 56 7.8E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS18460 eeed7e8741706ca887f7c5df4b00d6bc 127 PRINTS PR00050 Cold shock protein signature 24 33 7.8E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS18460 eeed7e8741706ca887f7c5df4b00d6bc 127 PRINTS PR00050 Cold shock protein signature 4 19 7.8E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS18460 eeed7e8741706ca887f7c5df4b00d6bc 127 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 5.7E-21 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS18460 eeed7e8741706ca887f7c5df4b00d6bc 127 Gene3D G3DSA:2.40.50.140 3 64 1.1E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS18460 eeed7e8741706ca887f7c5df4b00d6bc 127 SUPERFAMILY SSF50249 2 67 6.37E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS05350 fcb2d25dd7f9a7a05f87bd9c78abf6b8 237 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 5.9E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS05350 fcb2d25dd7f9a7a05f87bd9c78abf6b8 237 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 5.9E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS05350 fcb2d25dd7f9a7a05f87bd9c78abf6b8 237 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 5.9E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS05350 fcb2d25dd7f9a7a05f87bd9c78abf6b8 237 Gene3D G3DSA:1.10.10.10 5 92 8.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05350 fcb2d25dd7f9a7a05f87bd9c78abf6b8 237 Pfam PF12840 Helix-turn-helix domain 14 72 7.1E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05350 fcb2d25dd7f9a7a05f87bd9c78abf6b8 237 SMART SM00418 12 92 1.3E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS05350 fcb2d25dd7f9a7a05f87bd9c78abf6b8 237 SUPERFAMILY SSF46785 8 91 3.64E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 SMART SM00331 474 682 9.5E-22 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 SMART SM00065 302 453 7.9E-5 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 SUPERFAMILY SSF55874 722 790 6.27E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 SUPERFAMILY SSF55781 305 454 7.2E-13 T 06-07-2017 IPR029016 GAF domain-like LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 Gene3D G3DSA:3.30.450.20 183 276 1.2E-11 T 06-07-2017 LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 Pfam PF08447 PAS fold 188 274 9.2E-12 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 Gene3D G3DSA:3.30.450.40 282 452 9.6E-12 T 06-07-2017 IPR029016 GAF domain-like LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 SUPERFAMILY SSF55785 181 280 3.66E-10 T 06-07-2017 IPR000014 PAS domain LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 SMART SM00086 238 280 4.4E-4 T 06-07-2017 IPR001610 PAC motif LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 Pfam PF13581 Histidine kinase-like ATPase domain 697 793 1.3E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 SUPERFAMILY SSF55781 30 158 5.23E-7 T 06-07-2017 IPR029016 GAF domain-like LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 SUPERFAMILY SSF81606 488 681 4.18E-7 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 501 682 6.9E-44 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01000 dbe0712e306549130f3ca4da6f685a14 821 Gene3D G3DSA:3.30.450.40 22 157 1.3E-4 T 06-07-2017 IPR029016 GAF domain-like LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 Gene3D G3DSA:2.40.30.10 231 316 5.0E-14 T 06-07-2017 LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 SUPERFAMILY SSF50465 322 423 7.19E-27 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 SUPERFAMILY SSF52540 14 217 9.55E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 Gene3D G3DSA:2.40.30.10 322 423 6.1E-6 T 06-07-2017 LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 68 83 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 Pfam PF00009 Elongation factor Tu GTP binding domain 15 198 1.3E-39 T 06-07-2017 LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 SUPERFAMILY SSF50447 230 317 3.53E-17 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 15 423 2.3E-164 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 PRINTS PR00315 GTP-binding elongation factor signature 148 157 2.0E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 PRINTS PR00315 GTP-binding elongation factor signature 111 122 2.0E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 PRINTS PR00315 GTP-binding elongation factor signature 16 29 2.0E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 PRINTS PR00315 GTP-binding elongation factor signature 75 83 2.0E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 PRINTS PR00315 GTP-binding elongation factor signature 95 105 2.0E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS26945 b2fdd363d16b5b8885965c5dc80fe514 444 Gene3D G3DSA:3.40.50.300 12 219 1.4E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10145 260bade48c09e4a21265ec67a84eb7b5 342 Gene3D G3DSA:3.40.190.10 176 284 6.9E-16 T 06-07-2017 LK06_RS10145 260bade48c09e4a21265ec67a84eb7b5 342 SUPERFAMILY SSF53850 22 39 1.63E-47 T 06-07-2017 LK06_RS10145 260bade48c09e4a21265ec67a84eb7b5 342 SUPERFAMILY SSF53850 78 320 1.63E-47 T 06-07-2017 LK06_RS10145 260bade48c09e4a21265ec67a84eb7b5 342 SMART SM00062 92 323 2.9E-38 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LK06_RS10145 260bade48c09e4a21265ec67a84eb7b5 342 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 93 321 8.4E-44 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LK06_RS10145 260bade48c09e4a21265ec67a84eb7b5 342 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 118 131 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 LK06_RS10145 260bade48c09e4a21265ec67a84eb7b5 342 Gene3D G3DSA:3.40.190.10 90 175 2.4E-29 T 06-07-2017 LK06_RS10145 260bade48c09e4a21265ec67a84eb7b5 342 Gene3D G3DSA:3.40.190.10 285 321 2.4E-29 T 06-07-2017 LK06_RS29770 8d45792d1d32ca90d262aa9afad9ae3d 394 SUPERFAMILY SSF53901 248 393 2.73E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29770 8d45792d1d32ca90d262aa9afad9ae3d 394 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 105 242 3.5E-16 T 06-07-2017 IPR001099 Chalcone/stilbene synthase, N-terminal LK06_RS29770 8d45792d1d32ca90d262aa9afad9ae3d 394 Gene3D G3DSA:3.40.47.10 251 389 9.3E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29770 8d45792d1d32ca90d262aa9afad9ae3d 394 PIRSF PIRSF000451 15 394 2.3E-92 T 06-07-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 LK06_RS29770 8d45792d1d32ca90d262aa9afad9ae3d 394 Gene3D G3DSA:3.40.47.10 1 57 1.9E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29770 8d45792d1d32ca90d262aa9afad9ae3d 394 Gene3D G3DSA:3.40.47.10 99 246 1.9E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29770 8d45792d1d32ca90d262aa9afad9ae3d 394 SUPERFAMILY SSF53901 103 245 5.99E-32 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03330 ba072707c229e1e2a69be9185f6b15d3 231 SUPERFAMILY SSF50475 17 203 4.91E-61 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS03330 ba072707c229e1e2a69be9185f6b15d3 231 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 36 182 2.6E-50 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related LK06_RS03330 ba072707c229e1e2a69be9185f6b15d3 231 Gene3D G3DSA:2.30.110.10 12 203 5.5E-77 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS31720 a4549818c5262fe5441dedff1c84f740 329 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS31720 a4549818c5262fe5441dedff1c84f740 329 SUPERFAMILY SSF52540 19 229 1.04E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31720 a4549818c5262fe5441dedff1c84f740 329 Pfam PF00005 ABC transporter 25 167 1.2E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS31720 a4549818c5262fe5441dedff1c84f740 329 Pfam PF13732 Domain of unknown function (DUF4162) 221 320 8.8E-7 T 06-07-2017 IPR025302 Domain of unknown function DUF4162 LK06_RS31720 a4549818c5262fe5441dedff1c84f740 329 Gene3D G3DSA:3.40.50.300 6 229 1.8E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31720 a4549818c5262fe5441dedff1c84f740 329 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 21 323 1.4E-95 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 LK06_RS31720 a4549818c5262fe5441dedff1c84f740 329 SMART SM00382 33 218 1.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS08315 56730f7c8459c56b710682ef90600108 330 SUPERFAMILY SSF53335 53 214 1.14E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS08315 56730f7c8459c56b710682ef90600108 330 Gene3D G3DSA:3.40.50.150 77 182 2.3E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS08315 56730f7c8459c56b710682ef90600108 330 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 53 324 3.5E-111 T 06-07-2017 IPR015324 Ribosomal protein Rsm22, bacterial-type GO:0006412|GO:0008168 LK06_RS13935 cdda9f958f9220cfe9410c881814b64e 247 SMART SM00448 6 129 4.2E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS13935 cdda9f958f9220cfe9410c881814b64e 247 SUPERFAMILY SSF52172 6 198 2.2E-39 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS13935 cdda9f958f9220cfe9410c881814b64e 247 SMART SM00862 163 240 1.7E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS13935 cdda9f958f9220cfe9410c881814b64e 247 Gene3D G3DSA:3.40.50.2300 5 137 1.4E-39 T 06-07-2017 LK06_RS13935 cdda9f958f9220cfe9410c881814b64e 247 Gene3D G3DSA:1.10.10.10 140 242 8.9E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13935 cdda9f958f9220cfe9410c881814b64e 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 240 3.4E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS13935 cdda9f958f9220cfe9410c881814b64e 247 Pfam PF00072 Response regulator receiver domain 9 130 1.2E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS22105 55988dd41d5a006333b089a102c7f904 298 Gene3D G3DSA:3.40.50.1010 28 175 9.6E-16 T 06-07-2017 IPR029060 PIN domain-like LK06_RS22105 55988dd41d5a006333b089a102c7f904 298 Pfam PF01936 NYN domain 34 180 3.3E-10 T 06-07-2017 IPR021139 NYN domain, limkain-b1-type LK06_RS24615 96be243a94baa8041dc80c5d9fb46fb0 187 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 23 182 6.1E-52 T 06-07-2017 IPR012816 NADAR LK06_RS24615 96be243a94baa8041dc80c5d9fb46fb0 187 Pfam PF08719 Domain of unknown function (DUF1768) 25 182 1.2E-53 T 06-07-2017 IPR012816 NADAR LK06_RS24615 96be243a94baa8041dc80c5d9fb46fb0 187 SUPERFAMILY SSF143990 20 183 4.71E-50 T 06-07-2017 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 SUPERFAMILY SSF81338 20 287 3.92E-68 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 TIGRFAM TIGR00861 MIP: MIP family channel proteins 26 283 2.7E-63 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 ProSitePatterns PS00221 MIP family signature. 93 101 - T 06-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 Gene3D G3DSA:1.20.1080.10 20 288 7.4E-81 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 Pfam PF00230 Major intrinsic protein 20 283 7.4E-56 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 PRINTS PR00783 Major intrinsic protein family signature 266 286 2.0E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 PRINTS PR00783 Major intrinsic protein family signature 112 131 2.0E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 PRINTS PR00783 Major intrinsic protein family signature 75 99 2.0E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 PRINTS PR00783 Major intrinsic protein family signature 22 41 2.0E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 PRINTS PR00783 Major intrinsic protein family signature 180 198 2.0E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS15185 4b1c33311626fab2fd46d93c730e1aa4 317 PRINTS PR00783 Major intrinsic protein family signature 213 235 2.0E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS23965 4d85906789447630dfa1b0c7e0ad39a1 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 4.8E-64 T 06-07-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 LK06_RS23965 4d85906789447630dfa1b0c7e0ad39a1 332 Gene3D G3DSA:3.50.50.60 10 37 7.7E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS23965 4d85906789447630dfa1b0c7e0ad39a1 332 Gene3D G3DSA:1.10.1040.10 38 326 4.7E-113 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS23965 4d85906789447630dfa1b0c7e0ad39a1 332 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 2 329 44.935 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 LK06_RS23965 4d85906789447630dfa1b0c7e0ad39a1 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 1.4E-133 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 LK06_RS23965 4d85906789447630dfa1b0c7e0ad39a1 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 3.3E-78 T 06-07-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 LK06_RS23965 4d85906789447630dfa1b0c7e0ad39a1 332 SUPERFAMILY SSF51735 3 183 4.35E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23965 4d85906789447630dfa1b0c7e0ad39a1 332 SUPERFAMILY SSF48179 184 329 3.23E-68 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 Gene3D G3DSA:3.30.360.10 162 316 8.3E-76 T 06-07-2017 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 SUPERFAMILY SSF55347 153 315 5.95E-71 T 06-07-2017 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 326 6.1E-140 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 SMART SM00846 3 153 7.2E-98 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 153 1.3E-62 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 Gene3D G3DSA:3.40.50.720 2 161 1.4E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 PIRSF PIRSF000149 1 334 3.4E-137 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 2.3E-41 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 2.3E-41 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 2.3E-41 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 2.3E-41 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 2.3E-41 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 314 2.8E-70 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06625 077c25544873291fe3ebaaa25fee1b7c 335 SUPERFAMILY SSF51735 3 169 1.53E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23195 707522196d13bbdf974127b67bbfd1f2 186 Gene3D G3DSA:3.40.50.2300 22 140 5.0E-36 T 06-07-2017 LK06_RS23195 707522196d13bbdf974127b67bbfd1f2 186 Pfam PF00072 Response regulator receiver domain 24 134 2.2E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS23195 707522196d13bbdf974127b67bbfd1f2 186 SUPERFAMILY SSF52172 15 142 2.99E-34 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS23195 707522196d13bbdf974127b67bbfd1f2 186 SMART SM00448 22 134 2.2E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS19970 5714e4f8be43353f2042dc518a48a708 90 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 52 1.9E-13 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LK06_RS19970 5714e4f8be43353f2042dc518a48a708 90 Gene3D G3DSA:3.40.1620.10 3 52 9.0E-23 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LK06_RS19970 5714e4f8be43353f2042dc518a48a708 90 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 69 2.2E-16 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LK06_RS19970 5714e4f8be43353f2042dc518a48a708 90 SUPERFAMILY SSF143120 4 67 7.72E-13 T 06-07-2017 LK06_RS23860 1dd0487edc756ea2b5e439d7b5b99d83 179 Pfam PF03641 Possible lysine decarboxylase 44 171 1.5E-30 T 06-07-2017 IPR031100 LOG family LK06_RS23860 1dd0487edc756ea2b5e439d7b5b99d83 179 Gene3D G3DSA:3.40.50.450 2 174 3.3E-43 T 06-07-2017 LK06_RS23860 1dd0487edc756ea2b5e439d7b5b99d83 179 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 173 1.5E-34 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG LK06_RS23860 1dd0487edc756ea2b5e439d7b5b99d83 179 SUPERFAMILY SSF102405 1 174 1.68E-41 T 06-07-2017 LK06_RS17615 67339564a1cb4b9493d0d1b0bffbcdbd 96 Gene3D G3DSA:2.60.40.10 19 84 2.7E-6 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS17615 67339564a1cb4b9493d0d1b0bffbcdbd 96 SUPERFAMILY SSF49452 17 93 1.08E-6 T 06-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 LK06_RS17615 67339564a1cb4b9493d0d1b0bffbcdbd 96 Pfam PF07210 Protein of unknown function (DUF1416) 2 96 3.2E-35 T 06-07-2017 IPR010814 Protein of unknown function DUF1416 LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 Gene3D G3DSA:1.10.1200.10 567 641 5.4E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 Pfam PF00550 Phosphopantetheine attachment site 576 636 2.8E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 Gene3D G3DSA:3.40.50.980 212 375 2.0E-48 T 06-07-2017 LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 Pfam PF00501 AMP-binding enzyme 65 462 2.0E-101 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 SUPERFAMILY SSF47336 572 639 2.49E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 Gene3D G3DSA:3.40.50.980 60 211 4.7E-48 T 06-07-2017 LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 ProSitePatterns PS00012 Phosphopantetheine attachment site. 597 612 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 86 486 3.4E-129 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 PRINTS PR00154 AMP-binding signature 210 218 7.4E-5 T 06-07-2017 IPR020459 AMP-binding LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 PRINTS PR00154 AMP-binding signature 198 209 7.4E-5 T 06-07-2017 IPR020459 AMP-binding LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 SMART SM00823 Phosphopantetheine attachment site 574 642 0.0073 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 548 1.5E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 SUPERFAMILY SSF56801 40 587 2.22E-150 T 06-07-2017 LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 Gene3D G3DSA:3.30.300.30 456 560 2.9E-27 T 06-07-2017 LK06_RS03290 f796d66eeba200a3a5ada75c4efe0a1d 651 Gene3D G3DSA:2.30.38.10 376 450 6.2E-26 T 06-07-2017 LK06_RS25990 ac25ae58c6e99acf5c58c7f49277e607 727 Gene3D G3DSA:3.40.50.280 560 719 1.4E-71 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS25990 ac25ae58c6e99acf5c58c7f49277e607 727 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 381 406 - T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS25990 ac25ae58c6e99acf5c58c7f49277e607 727 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 38 561 3.0E-278 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS25990 ac25ae58c6e99acf5c58c7f49277e607 727 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 593 721 2.9E-62 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS25990 ac25ae58c6e99acf5c58c7f49277e607 727 Gene3D G3DSA:3.20.20.240 38 508 2.5E-206 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS25990 ac25ae58c6e99acf5c58c7f49277e607 727 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 1.0E-234 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS25990 ac25ae58c6e99acf5c58c7f49277e607 727 SUPERFAMILY SSF51703 21 556 5.76E-219 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS25990 ac25ae58c6e99acf5c58c7f49277e607 727 Pfam PF02310 B12 binding domain 596 706 5.2E-14 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS25990 ac25ae58c6e99acf5c58c7f49277e607 727 SUPERFAMILY SSF52242 559 722 4.45E-59 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS11130 4d439933d922968b97f2ed529d7766a3 1096 Pfam PF00905 Penicillin binding protein transpeptidase domain 645 896 8.4E-32 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS11130 4d439933d922968b97f2ed529d7766a3 1096 Gene3D G3DSA:1.10.3810.10 368 542 9.9E-65 T 06-07-2017 LK06_RS11130 4d439933d922968b97f2ed529d7766a3 1096 SUPERFAMILY SSF56601 575 950 3.89E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS11130 4d439933d922968b97f2ed529d7766a3 1096 SUPERFAMILY SSF56601 527 546 3.89E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS11130 4d439933d922968b97f2ed529d7766a3 1096 Gene3D G3DSA:3.40.710.10 543 957 1.0E-96 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS11130 4d439933d922968b97f2ed529d7766a3 1096 SUPERFAMILY SSF53955 355 556 2.81E-62 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS11130 4d439933d922968b97f2ed529d7766a3 1096 Pfam PF00912 Transglycosylase 373 542 6.0E-57 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 LK06_RS00075 ae87b11a391d34595f144f9304f0f99d 502 Gene3D G3DSA:3.30.750.24 414 489 7.2E-10 T 06-07-2017 IPR002645 STAS domain LK06_RS00075 ae87b11a391d34595f144f9304f0f99d 502 SUPERFAMILY SSF52091 413 489 1.88E-12 T 06-07-2017 IPR002645 STAS domain LK06_RS00075 ae87b11a391d34595f144f9304f0f99d 502 Pfam PF00916 Sulfate permease family 27 156 3.7E-20 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 LK06_RS00075 ae87b11a391d34595f144f9304f0f99d 502 Pfam PF00916 Sulfate permease family 178 371 8.2E-25 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 LK06_RS00075 ae87b11a391d34595f144f9304f0f99d 502 Pfam PF01740 STAS domain 414 489 4.0E-9 T 06-07-2017 IPR002645 STAS domain LK06_RS02140 fbcc3a482ed3b613bf4780e27630d9d8 230 SUPERFAMILY SSF48008 95 226 4.45E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS02140 fbcc3a482ed3b613bf4780e27630d9d8 230 Gene3D G3DSA:1.20.120.530 91 225 7.1E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS02140 fbcc3a482ed3b613bf4780e27630d9d8 230 SUPERFAMILY SSF46785 22 91 8.17E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02140 fbcc3a482ed3b613bf4780e27630d9d8 230 SMART SM00345 29 87 5.0E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS02140 fbcc3a482ed3b613bf4780e27630d9d8 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 87 7.5E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS02140 fbcc3a482ed3b613bf4780e27630d9d8 230 SMART SM00895 97 221 4.9E-12 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS02140 fbcc3a482ed3b613bf4780e27630d9d8 230 Gene3D G3DSA:1.10.10.10 20 88 4.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02140 fbcc3a482ed3b613bf4780e27630d9d8 230 Pfam PF07729 FCD domain 99 219 2.5E-20 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 SUPERFAMILY SSF52540 295 507 7.71E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 SMART SM00382 328 456 2.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 Gene3D G3DSA:1.10.8.60 462 531 2.0E-28 T 06-07-2017 LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 SUPERFAMILY SSF48295 539 634 3.92E-34 T 06-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 Gene3D G3DSA:1.10.1750.10 538 634 1.2E-38 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 SMART SM00760 542 611 3.9E-36 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 ProSitePatterns PS01008 DnaA protein signature. 592 611 - T 06-07-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 545 611 2.0E-29 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 633 33.37 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 Pfam PF00308 Bacterial dnaA protein 296 513 1.1E-103 T 06-07-2017 IPR013317 Chromosomal replication initiator protein DnaA LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 592 611 6.4E-52 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 329 349 6.4E-52 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 361 375 6.4E-52 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 393 407 6.4E-52 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 427 454 6.4E-52 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 Gene3D G3DSA:3.40.50.300 293 460 1.5E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15860 b9c26fb1e6578b3a970736a899d5d0e0 635 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 280 632 9.7E-150 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 LK06_RS07595 b5234fc5e2421a81b3439d53b981a3a8 247 Gene3D G3DSA:1.20.1540.10 21 225 7.1E-33 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 LK06_RS07595 b5234fc5e2421a81b3439d53b981a3a8 247 Pfam PF01694 Rhomboid family 83 228 3.4E-34 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 LK06_RS07595 b5234fc5e2421a81b3439d53b981a3a8 247 SUPERFAMILY SSF144091 21 226 3.14E-33 T 06-07-2017 LK06_RS26410 c2e2e9fedc46d6a6fad1fdf4e5a04b2f 520 Gene3D G3DSA:1.10.3140.10 3 145 2.1E-44 T 06-07-2017 LK06_RS26410 c2e2e9fedc46d6a6fad1fdf4e5a04b2f 520 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 299 479 3.8E-46 T 06-07-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal LK06_RS26410 c2e2e9fedc46d6a6fad1fdf4e5a04b2f 520 PIRSF PIRSF000331 1 488 8.8E-140 T 06-07-2017 IPR004925 HpaB/PvcC/4-BUDH LK06_RS26410 c2e2e9fedc46d6a6fad1fdf4e5a04b2f 520 Gene3D G3DSA:2.40.110.10 146 264 6.9E-49 T 06-07-2017 LK06_RS26410 c2e2e9fedc46d6a6fad1fdf4e5a04b2f 520 SUPERFAMILY SSF56645 4 272 8.77E-85 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS26410 c2e2e9fedc46d6a6fad1fdf4e5a04b2f 520 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 272 3.9E-98 T 06-07-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal LK06_RS26410 c2e2e9fedc46d6a6fad1fdf4e5a04b2f 520 Gene3D G3DSA:1.20.140.10 265 480 1.5E-44 T 06-07-2017 LK06_RS26410 c2e2e9fedc46d6a6fad1fdf4e5a04b2f 520 SUPERFAMILY SSF47203 264 480 9.21E-46 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS19130 6c65648933b891fcc39abeb26e8b9abe 224 Pfam PF01738 Dienelactone hydrolase family 9 215 2.6E-48 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 LK06_RS19130 6c65648933b891fcc39abeb26e8b9abe 224 Gene3D G3DSA:3.40.50.1820 9 215 4.9E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS19130 6c65648933b891fcc39abeb26e8b9abe 224 SUPERFAMILY SSF53474 9 215 9.86E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS12135 a6626fcdf43c2954eab04174d56cd475 615 Gene3D G3DSA:3.40.50.10490 445 615 5.9E-61 T 06-07-2017 LK06_RS12135 a6626fcdf43c2954eab04174d56cd475 615 Gene3D G3DSA:3.40.50.10490 246 444 4.3E-73 T 06-07-2017 LK06_RS12135 a6626fcdf43c2954eab04174d56cd475 615 SUPERFAMILY SSF53697 247 615 7.79E-107 T 06-07-2017 LK06_RS12135 a6626fcdf43c2954eab04174d56cd475 615 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 615 5.3E-248 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 LK06_RS12135 a6626fcdf43c2954eab04174d56cd475 615 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 615 41.304 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 LK06_RS12135 a6626fcdf43c2954eab04174d56cd475 615 SUPERFAMILY SSF56235 2 231 4.72E-68 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS12135 a6626fcdf43c2954eab04174d56cd475 615 Pfam PF13522 Glutamine amidotransferase domain 66 194 1.8E-21 T 06-07-2017 LK06_RS12135 a6626fcdf43c2954eab04174d56cd475 615 Pfam PF01380 SIS domain 464 596 6.8E-24 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 LK06_RS12135 a6626fcdf43c2954eab04174d56cd475 615 Pfam PF01380 SIS domain 291 418 6.3E-33 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 LK06_RS12135 a6626fcdf43c2954eab04174d56cd475 615 Gene3D G3DSA:3.60.20.10 2 242 1.8E-74 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 SUPERFAMILY SSF46894 842 905 1.09E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 SMART SM00421 850 907 5.1E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 Gene3D G3DSA:1.10.10.10 849 903 2.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 Gene3D G3DSA:1.25.40.10 566 597 8.4E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 Gene3D G3DSA:1.25.40.10 667 836 8.4E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 Gene3D G3DSA:1.25.40.10 371 503 3.3E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 SUPERFAMILY SSF52540 14 218 4.95E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 867 883 9.4E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 883 895 9.4E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 853 867 9.4E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 Pfam PF13191 AAA ATPase domain 13 143 4.4E-13 T 06-07-2017 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 Gene3D G3DSA:3.40.50.300 25 166 4.7E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 ProSitePatterns PS00622 LuxR-type HTH domain signature. 867 894 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 Pfam PF00196 Bacterial regulatory proteins, luxR family 852 900 1.4E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 SUPERFAMILY SSF48371 210 355 1.55E-6 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS32040 6011da5ab71897561ec7ef08fe394e46 925 SUPERFAMILY SSF48371 392 521 1.55E-6 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS25230 86c5e4013e4f3060d6a78f2a0e135571 233 SUPERFAMILY SSF53098 18 213 9.56E-57 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS25230 86c5e4013e4f3060d6a78f2a0e135571 233 Hamap MF_00052_B Ribonuclease HII [rnhB]. 22 202 36.109 T 06-07-2017 IPR022898 Ribonuclease HII GO:0004523 LK06_RS25230 86c5e4013e4f3060d6a78f2a0e135571 233 Pfam PF01351 Ribonuclease HII 24 200 9.4E-34 T 06-07-2017 IPR024567 Ribonuclease HII/HIII domain LK06_RS25230 86c5e4013e4f3060d6a78f2a0e135571 233 Gene3D G3DSA:3.30.420.10 22 162 5.7E-39 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 Pfam PF01966 HD domain 455 571 3.6E-12 T 06-07-2017 IPR006674 HD domain LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 Gene3D G3DSA:1.10.3210.10 435 596 1.0E-18 T 06-07-2017 IPR006674 HD domain LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 SUPERFAMILY SSF81593 172 283 1.26E-6 T 06-07-2017 LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 837 89.619 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 23 835 2.0E-242 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 SUPERFAMILY SSF55021 766 829 6.49E-7 T 06-07-2017 LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 Gene3D G3DSA:3.30.70.260 766 819 1.9E-7 T 06-07-2017 LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 SUPERFAMILY SSF81301 38 160 5.72E-14 T 06-07-2017 LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 SMART SM00471 450 582 6.9E-10 T 06-07-2017 IPR003607 HD/PDEase domain LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 Gene3D G3DSA:3.30.460.10 66 122 6.9E-4 T 06-07-2017 LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 Pfam PF01842 ACT domain 766 817 1.9E-6 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 SUPERFAMILY SSF109604 422 535 2.83E-14 T 06-07-2017 LK06_RS24385 71a2f9bae34ec4e5ebae733641e450de 837 Pfam PF08335 GlnD PII-uridylyltransferase 212 285 6.7E-7 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 LK06_RS09240 1e32cb670f7d04058ea558cf96e4186e 187 Pfam PF14016 Protein of unknown function (DUF4232) 57 181 4.9E-35 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 LK06_RS29075 49ec3b686b396cccb54a9488f939253e 335 SUPERFAMILY SSF47413 2 61 7.5E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS29075 49ec3b686b396cccb54a9488f939253e 335 Gene3D G3DSA:3.40.50.2300 56 175 3.5E-37 T 06-07-2017 LK06_RS29075 49ec3b686b396cccb54a9488f939253e 335 SMART SM00354 3 73 6.8E-29 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS29075 49ec3b686b396cccb54a9488f939253e 335 Gene3D G3DSA:1.10.260.40 4 55 5.2E-25 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS29075 49ec3b686b396cccb54a9488f939253e 335 Gene3D G3DSA:3.40.50.2300 176 303 3.8E-42 T 06-07-2017 LK06_RS29075 49ec3b686b396cccb54a9488f939253e 335 Pfam PF13377 Periplasmic binding protein-like domain 170 326 3.6E-34 T 06-07-2017 LK06_RS29075 49ec3b686b396cccb54a9488f939253e 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 5.5E-16 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS29075 49ec3b686b396cccb54a9488f939253e 335 SUPERFAMILY SSF53822 62 329 5.55E-64 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS31885 4ceb4ae35bad8f7f8b8fc537f420f8af 224 Gene3D G3DSA:1.10.10.10 168 224 1.9E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31885 4ceb4ae35bad8f7f8b8fc537f420f8af 224 SUPERFAMILY SSF46894 153 223 1.39E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS31885 4ceb4ae35bad8f7f8b8fc537f420f8af 224 Gene3D G3DSA:3.40.50.2300 23 167 7.9E-12 T 06-07-2017 LK06_RS31885 4ceb4ae35bad8f7f8b8fc537f420f8af 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 218 4.4E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS31885 4ceb4ae35bad8f7f8b8fc537f420f8af 224 SUPERFAMILY SSF52172 23 144 1.15E-10 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS31885 4ceb4ae35bad8f7f8b8fc537f420f8af 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 2.4E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS31885 4ceb4ae35bad8f7f8b8fc537f420f8af 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 2.4E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS31885 4ceb4ae35bad8f7f8b8fc537f420f8af 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 2.4E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS31885 4ceb4ae35bad8f7f8b8fc537f420f8af 224 SMART SM00421 161 218 1.2E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS31885 4ceb4ae35bad8f7f8b8fc537f420f8af 224 Pfam PF00072 Response regulator receiver domain 27 137 2.1E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS27315 2c3ccc254b65400334e73a840ffdb63e 379 Gene3D G3DSA:1.20.58.340 176 286 5.4E-40 T 06-07-2017 LK06_RS27315 2c3ccc254b65400334e73a840ffdb63e 379 Gene3D G3DSA:3.30.460.20 24 175 6.4E-41 T 06-07-2017 LK06_RS27315 2c3ccc254b65400334e73a840ffdb63e 379 Pfam PF01544 CorA-like Mg2+ transporter protein 74 375 9.5E-65 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 LK06_RS27315 2c3ccc254b65400334e73a840ffdb63e 379 SUPERFAMILY SSF143865 29 296 4.18E-66 T 06-07-2017 LK06_RS27315 2c3ccc254b65400334e73a840ffdb63e 379 Gene3D G3DSA:1.20.58.340 309 379 1.3E-23 T 06-07-2017 LK06_RS27315 2c3ccc254b65400334e73a840ffdb63e 379 SUPERFAMILY SSF144083 314 376 1.31E-18 T 06-07-2017 LK06_RS07560 bdbdfaecf9f2d2055cb43732168bdd44 380 Pfam PF00534 Glycosyl transferases group 1 192 362 9.1E-42 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS07560 bdbdfaecf9f2d2055cb43732168bdd44 380 Pfam PF13439 Glycosyltransferase Family 4 16 178 1.4E-7 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS07560 bdbdfaecf9f2d2055cb43732168bdd44 380 Gene3D G3DSA:3.40.50.2000 168 361 2.9E-36 T 06-07-2017 LK06_RS07560 bdbdfaecf9f2d2055cb43732168bdd44 380 SUPERFAMILY SSF53756 5 380 3.26E-75 T 06-07-2017 LK06_RS03620 c24eb1a6ac98ff92f054669acd8e875d 481 SUPERFAMILY SSF100879 243 342 1.37E-24 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS03620 c24eb1a6ac98ff92f054669acd8e875d 481 Gene3D G3DSA:3.30.70.270 69 168 1.3E-24 T 06-07-2017 LK06_RS03620 c24eb1a6ac98ff92f054669acd8e875d 481 Gene3D G3DSA:1.10.150.20 170 239 1.1E-18 T 06-07-2017 LK06_RS03620 c24eb1a6ac98ff92f054669acd8e875d 481 Pfam PF00817 impB/mucB/samB family 10 158 1.4E-41 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS03620 c24eb1a6ac98ff92f054669acd8e875d 481 Gene3D G3DSA:3.30.1490.100 246 352 2.7E-29 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS03620 c24eb1a6ac98ff92f054669acd8e875d 481 Pfam PF14520 Helix-hairpin-helix domain 184 218 1.5E-5 T 06-07-2017 LK06_RS03620 c24eb1a6ac98ff92f054669acd8e875d 481 SUPERFAMILY SSF56672 6 239 1.87E-70 T 06-07-2017 LK06_RS03620 c24eb1a6ac98ff92f054669acd8e875d 481 Pfam PF11799 impB/mucB/samB family C-terminal domain 241 346 1.6E-19 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS03620 c24eb1a6ac98ff92f054669acd8e875d 481 Hamap MF_01113 DNA polymerase IV [dinB]. 4 352 34.243 T 06-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 SUPERFAMILY SSF47819 678 758 3.49E-17 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 Gene3D G3DSA:3.40.50.300 331 444 1.1E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 Gene3D G3DSA:3.40.50.300 536 620 1.1E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 Pfam PF00570 HRDC domain 689 754 7.1E-18 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 SUPERFAMILY SSF52540 53 620 4.14E-119 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 SMART SM00341 685 765 3.0E-15 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 Gene3D G3DSA:1.10.150.80 688 752 6.4E-11 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 Gene3D G3DSA:3.40.50.300 56 324 5.9E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 Pfam PF00580 UvrD/REP helicase N-terminal domain 217 319 2.9E-25 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 Pfam PF00580 UvrD/REP helicase N-terminal domain 57 138 1.5E-20 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 Pfam PF13361 UvrD-like helicase C-terminal domain 327 443 2.3E-13 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 LK06_RS22230 6cd4b4e2cbbb0bca90d59122da5f2d63 767 Pfam PF13361 UvrD-like helicase C-terminal domain 492 599 2.8E-23 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 LK06_RS24990 95df1d9bf8ee51b7d6f520409c2e79c9 267 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 126 148 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS24990 95df1d9bf8ee51b7d6f520409c2e79c9 267 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 78 247 2.3E-35 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 LK06_RS24990 95df1d9bf8ee51b7d6f520409c2e79c9 267 Pfam PF01066 CDP-alcohol phosphatidyltransferase 78 148 4.7E-15 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS00135 ff587b74ec3ffd92e9cbed59337de62f 156 Gene3D G3DSA:2.30.110.10 8 142 1.1E-31 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS00135 ff587b74ec3ffd92e9cbed59337de62f 156 SUPERFAMILY SSF50475 12 138 1.69E-16 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS00135 ff587b74ec3ffd92e9cbed59337de62f 156 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 15 138 5.5E-26 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related LK06_RS16920 c930fd77e1f54b517c1f6fa59262091d 70 SUPERFAMILY SSF56349 2 64 2.53E-10 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS16920 c930fd77e1f54b517c1f6fa59262091d 70 Pfam PF00589 Phage integrase family 2 55 2.5E-5 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS16920 c930fd77e1f54b517c1f6fa59262091d 70 Gene3D G3DSA:1.10.443.10 1 67 1.5E-10 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS19655 541cb8e8929abc2b01c54a3c718b2a8f 252 SMART SM00382 33 247 2.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS19655 541cb8e8929abc2b01c54a3c718b2a8f 252 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 17 198 1.1E-63 T 06-07-2017 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 LK06_RS19655 541cb8e8929abc2b01c54a3c718b2a8f 252 SUPERFAMILY SSF52540 6 229 1.55E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19655 541cb8e8929abc2b01c54a3c718b2a8f 252 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS19655 541cb8e8929abc2b01c54a3c718b2a8f 252 Pfam PF00005 ABC transporter 26 169 1.8E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS19655 541cb8e8929abc2b01c54a3c718b2a8f 252 Gene3D G3DSA:3.40.50.300 5 232 8.5E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15135 2a50b5e89599cededbd127c254f11d34 362 SUPERFAMILY SSF81606 150 349 1.12E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15135 2a50b5e89599cededbd127c254f11d34 362 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 162 350 2.9E-40 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15135 2a50b5e89599cededbd127c254f11d34 362 SMART SM00331 136 350 2.6E-22 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 Gene3D G3DSA:3.40.50.720 28 245 3.3E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 SMART SM00984 343 438 1.1E-20 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 SUPERFAMILY SSF51735 31 218 3.85E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 29 433 1.1E-124 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 Gene3D G3DSA:3.40.50.720 256 435 6.3E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 PIRSF PIRSF000124 28 440 5.5E-59 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 30 204 2.9E-39 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 PIRSF PIRSF500136 19 442 1.8E-143 T 06-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 SUPERFAMILY SSF48179 224 322 7.65E-28 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 344 434 1.1E-14 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 SUPERFAMILY SSF52413 328 435 1.7E-20 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS28345 f26a913165dc47e2befbf66ac837711b 444 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 224 316 7.1E-26 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS02505 8ef578dbe1e740813299606a1da39e4a 647 Gene3D G3DSA:2.130.10.130 64 417 1.2E-18 T 06-07-2017 LK06_RS02505 8ef578dbe1e740813299606a1da39e4a 647 SUPERFAMILY SSF69318 57 431 2.49E-44 T 06-07-2017 LK06_RS02505 8ef578dbe1e740813299606a1da39e4a 647 SUPERFAMILY SSF69318 466 530 2.49E-44 T 06-07-2017 LK06_RS02505 8ef578dbe1e740813299606a1da39e4a 647 Pfam PF07593 ASPIC and UnbV 565 626 6.7E-13 T 06-07-2017 IPR011519 ASPIC/UnbV LK06_RS30920 d557c9a517268432367eca2f637f4c05 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 7.1E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS30920 d557c9a517268432367eca2f637f4c05 294 Gene3D G3DSA:3.40.190.10 92 196 2.4E-37 T 06-07-2017 LK06_RS30920 d557c9a517268432367eca2f637f4c05 294 SUPERFAMILY SSF46785 5 112 6.7E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30920 d557c9a517268432367eca2f637f4c05 294 Pfam PF03466 LysR substrate binding domain 94 284 4.0E-17 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS30920 d557c9a517268432367eca2f637f4c05 294 SUPERFAMILY SSF53850 87 284 6.33E-23 T 06-07-2017 LK06_RS30920 d557c9a517268432367eca2f637f4c05 294 Gene3D G3DSA:1.10.10.10 6 84 6.2E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30920 d557c9a517268432367eca2f637f4c05 294 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 6 291 1.8E-108 T 06-07-2017 IPR017685 HTH-type transcriptional regulator ArgP LK06_RS30645 56b76f76825000d36d70877fa0b1b967 480 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 295 478 6.8E-38 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS30645 56b76f76825000d36d70877fa0b1b967 480 SUPERFAMILY SSF81606 311 478 8.63E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS30645 56b76f76825000d36d70877fa0b1b967 480 Gene3D G3DSA:3.30.450.20 111 214 6.7E-12 T 06-07-2017 LK06_RS30645 56b76f76825000d36d70877fa0b1b967 480 Pfam PF08447 PAS fold 124 205 3.9E-9 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 LK06_RS30645 56b76f76825000d36d70877fa0b1b967 480 SUPERFAMILY SSF55785 111 214 1.05E-10 T 06-07-2017 IPR000014 PAS domain LK06_RS30645 56b76f76825000d36d70877fa0b1b967 480 SMART SM00331 269 478 1.8E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS13610 51ecd23fc7040557b486db70a07f144c 179 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 162 1.0E-60 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 LK06_RS13610 51ecd23fc7040557b486db70a07f144c 179 Gene3D G3DSA:1.10.1740.10 2 79 1.6E-13 T 06-07-2017 LK06_RS13610 51ecd23fc7040557b486db70a07f144c 179 SUPERFAMILY SSF88946 2 75 4.71E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS13610 51ecd23fc7040557b486db70a07f144c 179 Pfam PF08281 Sigma-70, region 4 104 155 3.3E-16 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS13610 51ecd23fc7040557b486db70a07f144c 179 Gene3D G3DSA:1.10.10.10 97 160 3.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13610 51ecd23fc7040557b486db70a07f144c 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 159 1.3E-25 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS13610 51ecd23fc7040557b486db70a07f144c 179 Pfam PF04542 Sigma-70 region 2 17 78 1.4E-7 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS13610 51ecd23fc7040557b486db70a07f144c 179 SUPERFAMILY SSF88659 91 160 1.5E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS13610 51ecd23fc7040557b486db70a07f144c 179 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 34 65 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS18345 2756e2922cf0ed76b8b7e0c9aa542c5b 471 Gene3D G3DSA:3.30.1360.60 10 84 2.4E-20 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 LK06_RS18345 2756e2922cf0ed76b8b7e0c9aa542c5b 471 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 LK06_RS18345 2756e2922cf0ed76b8b7e0c9aa542c5b 471 SUPERFAMILY SSF55604 10 77 1.7E-15 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 LK06_RS18345 2756e2922cf0ed76b8b7e0c9aa542c5b 471 Pfam PF02378 Phosphotransferase system, EIIC 128 395 4.6E-22 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 LK06_RS18345 2756e2922cf0ed76b8b7e0c9aa542c5b 471 Pfam PF00367 phosphotransferase system, EIIB 12 43 3.4E-15 T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 LK06_RS14900 04e22e94a2996355b97d77d5c971651e 242 Gene3D G3DSA:3.40.50.2300 12 135 1.1E-36 T 06-07-2017 LK06_RS14900 04e22e94a2996355b97d77d5c971651e 242 SUPERFAMILY SSF52172 12 138 3.27E-37 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS14900 04e22e94a2996355b97d77d5c971651e 242 SMART SM00448 15 126 2.3E-36 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS14900 04e22e94a2996355b97d77d5c971651e 242 Gene3D G3DSA:1.10.10.10 139 239 2.3E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14900 04e22e94a2996355b97d77d5c971651e 242 Pfam PF00072 Response regulator receiver domain 17 126 7.5E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS14900 04e22e94a2996355b97d77d5c971651e 242 SMART SM00862 161 237 1.4E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS14900 04e22e94a2996355b97d77d5c971651e 242 SUPERFAMILY SSF46894 134 238 8.79E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS14900 04e22e94a2996355b97d77d5c971651e 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 237 5.5E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS17955 bb4f638b52ee8d466bb12adf4dab2523 458 Pfam PF01580 FtsK/SpoIIIE family 160 339 1.2E-26 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS17955 bb4f638b52ee8d466bb12adf4dab2523 458 Gene3D G3DSA:3.40.50.300 157 377 6.7E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17955 bb4f638b52ee8d466bb12adf4dab2523 458 SUPERFAMILY SSF52540 148 380 5.84E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16885 4ca9d5acf0b362ed9144d6bcb3ec0633 367 Pfam PF04055 Radical SAM superfamily 84 221 1.5E-11 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS16885 4ca9d5acf0b362ed9144d6bcb3ec0633 367 Gene3D G3DSA:3.20.20.70 72 342 2.8E-32 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS16885 4ca9d5acf0b362ed9144d6bcb3ec0633 367 SUPERFAMILY SSF102114 78 339 5.62E-36 T 06-07-2017 LK06_RS22405 426b2761cc2188994bc0e67813ed2066 216 Gene3D G3DSA:3.90.45.10 42 208 5.8E-58 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS22405 426b2761cc2188994bc0e67813ed2066 216 PRINTS PR01576 Peptide deformylase signature 71 100 2.9E-31 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS22405 426b2761cc2188994bc0e67813ed2066 216 PRINTS PR01576 Peptide deformylase signature 164 193 2.9E-31 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS22405 426b2761cc2188994bc0e67813ed2066 216 PRINTS PR01576 Peptide deformylase signature 133 144 2.9E-31 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS22405 426b2761cc2188994bc0e67813ed2066 216 PRINTS PR01576 Peptide deformylase signature 145 163 2.9E-31 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS22405 426b2761cc2188994bc0e67813ed2066 216 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 47 203 7.9E-40 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS22405 426b2761cc2188994bc0e67813ed2066 216 PIRSF PIRSF004749 22 214 1.2E-43 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS22405 426b2761cc2188994bc0e67813ed2066 216 Pfam PF01327 Polypeptide deformylase 42 196 9.4E-45 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS22405 426b2761cc2188994bc0e67813ed2066 216 Hamap MF_00163 Peptide deformylase [def]. 40 206 28.427 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS22405 426b2761cc2188994bc0e67813ed2066 216 SUPERFAMILY SSF56420 40 203 9.94E-53 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 Hamap MF_00942 Endonuclease III [nth]. 20 233 37.636 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 211 227 - T 06-07-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 SMART SM00478 62 209 5.3E-58 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 211 227 2.0E-4 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 58 191 6.2E-23 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 Gene3D G3DSA:1.10.340.30 46 146 8.2E-36 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 SUPERFAMILY SSF48150 30 237 5.65E-69 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 Pfam PF00633 Helix-hairpin-helix motif 124 146 3.8E-6 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 SMART SM00525 210 230 2.4E-6 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 TIGRFAM TIGR01083 nth: endonuclease III 29 218 2.3E-74 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 Gene3D G3DSA:1.10.1670.10 147 232 3.8E-33 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 LK06_RS14125 0cd17dc076b385e157ba0eca34ed7608 276 ProSitePatterns PS01155 Endonuclease III family signature. 126 155 - T 06-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 LK06_RS13295 85e02358b26caea666484c47c86c7a41 597 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 269 567 4.2E-110 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal LK06_RS13295 85e02358b26caea666484c47c86c7a41 597 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 42 245 3.1E-7 T 06-07-2017 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 LK06_RS13295 85e02358b26caea666484c47c86c7a41 597 SUPERFAMILY SSF55729 387 511 4.66E-5 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS30800 cc043dd8f9a5b52e57ed48668d8084b3 160 Gene3D G3DSA:3.10.180.10 5 131 1.1E-45 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30800 cc043dd8f9a5b52e57ed48668d8084b3 160 PIRSF PIRSF021700 1 159 1.7E-63 T 06-07-2017 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase LK06_RS30800 cc043dd8f9a5b52e57ed48668d8084b3 160 SUPERFAMILY SSF54593 6 157 2.51E-50 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30800 cc043dd8f9a5b52e57ed48668d8084b3 160 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 119 1.2E-49 T 06-07-2017 IPR028973 PhnB-like LK06_RS17355 6c9eb451b8f17b9a9ba650f6749e372d 845 Pfam PF04185 Phosphoesterase family 471 742 3.7E-13 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 LK06_RS17355 6c9eb451b8f17b9a9ba650f6749e372d 845 Pfam PF10282 Lactonase, 7-bladed beta-propeller 117 236 4.5E-7 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 LK06_RS17355 6c9eb451b8f17b9a9ba650f6749e372d 845 SUPERFAMILY SSF50974 8 375 1.73E-42 T 06-07-2017 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 LK06_RS17355 6c9eb451b8f17b9a9ba650f6749e372d 845 Gene3D G3DSA:2.130.10.10 64 349 2.3E-43 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS17355 6c9eb451b8f17b9a9ba650f6749e372d 845 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 263 291 2.2E-7 T 06-07-2017 IPR011964 YVTN beta-propeller repeat LK06_RS17355 6c9eb451b8f17b9a9ba650f6749e372d 845 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 311 349 2.7E-7 T 06-07-2017 IPR011964 YVTN beta-propeller repeat LK06_RS13070 cb6b08b39001cbda7b415d84bc26d65d 485 SUPERFAMILY SSF143968 320 485 3.53E-55 T 06-07-2017 LK06_RS13070 cb6b08b39001cbda7b415d84bc26d65d 485 Gene3D G3DSA:1.20.5.570 450 485 4.6E-5 T 06-07-2017 LK06_RS13070 cb6b08b39001cbda7b415d84bc26d65d 485 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 9 442 7.0E-196 T 06-07-2017 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 LK06_RS13070 cb6b08b39001cbda7b415d84bc26d65d 485 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 450 5.1E-138 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 LK06_RS13070 cb6b08b39001cbda7b415d84bc26d65d 485 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 425 4.9E-158 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 LK06_RS13070 cb6b08b39001cbda7b415d84bc26d65d 485 SUPERFAMILY SSF50475 3 319 6.28E-113 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS13070 cb6b08b39001cbda7b415d84bc26d65d 485 Gene3D G3DSA:3.40.1670.10 334 449 6.9E-39 T 06-07-2017 LK06_RS11940 4862158b84eeca7fb10087ea82ce8de5 393 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 112 267 1.3E-44 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS11940 4862158b84eeca7fb10087ea82ce8de5 393 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 112 267 1.0E-47 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS17450 da236627e81b1501282d20b140e99013 377 PIRSF PIRSF016578 2 377 9.5E-120 T 06-07-2017 LK06_RS17450 da236627e81b1501282d20b140e99013 377 SUPERFAMILY SSF56645 20 202 1.03E-27 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS17450 da236627e81b1501282d20b140e99013 377 Gene3D G3DSA:2.40.110.10 116 197 6.9E-28 T 06-07-2017 LK06_RS17450 da236627e81b1501282d20b140e99013 377 Gene3D G3DSA:1.20.140.10 198 372 1.1E-32 T 06-07-2017 LK06_RS17450 da236627e81b1501282d20b140e99013 377 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 234 359 6.6E-27 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain LK06_RS17450 da236627e81b1501282d20b140e99013 377 SUPERFAMILY SSF47203 231 355 7.33E-9 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS17450 da236627e81b1501282d20b140e99013 377 Gene3D G3DSA:1.10.540.10 15 110 1.6E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS16835 91caa5bad4cee86a7c6be1db344c9823 302 SUPERFAMILY SSF53098 118 294 1.52E-36 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS16835 91caa5bad4cee86a7c6be1db344c9823 302 Gene3D G3DSA:3.30.420.10 112 290 7.4E-45 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS16835 91caa5bad4cee86a7c6be1db344c9823 302 SUPERFAMILY SSF46689 6 96 3.23E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS16835 91caa5bad4cee86a7c6be1db344c9823 302 Pfam PF13011 leucine-zipper of insertion element IS481 4 67 2.2E-14 T 06-07-2017 IPR024967 DNA-binding domain, IS481-type LK06_RS16835 91caa5bad4cee86a7c6be1db344c9823 302 Pfam PF00665 Integrase core domain 117 253 7.8E-37 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 LK06_RS17800 7c51124218e24a220847e4fcff6bb6bf 166 Gene3D G3DSA:3.30.1460.10 11 141 1.3E-14 T 06-07-2017 LK06_RS17800 7c51124218e24a220847e4fcff6bb6bf 166 Pfam PF10722 Putative bacterial sensory transduction regulator 10 130 1.2E-17 T 06-07-2017 IPR019660 Putative sensory transduction regulator YbjN LK06_RS17800 7c51124218e24a220847e4fcff6bb6bf 166 SUPERFAMILY SSF69635 5 132 8.89E-31 T 06-07-2017 LK06_RS08110 202766d234b54512b928d8598ca3ec35 334 SUPERFAMILY SSF161098 89 319 2.75E-59 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS08110 202766d234b54512b928d8598ca3ec35 334 Gene3D G3DSA:1.10.3720.10 103 329 3.8E-64 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS08110 202766d234b54512b928d8598ca3ec35 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 323 1.2E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06615 8c88e04304459f0512a231f4e01131dd 258 SUPERFAMILY SSF51351 4 255 6.68E-93 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06615 8c88e04304459f0512a231f4e01131dd 258 ProSitePatterns PS00171 Triosephosphate isomerase active site. 171 181 - T 06-07-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06615 8c88e04304459f0512a231f4e01131dd 258 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 247 3.4E-57 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06615 8c88e04304459f0512a231f4e01131dd 258 Pfam PF00121 Triosephosphate isomerase 7 253 5.8E-91 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06615 8c88e04304459f0512a231f4e01131dd 258 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 256 40.198 T 06-07-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06615 8c88e04304459f0512a231f4e01131dd 258 Gene3D G3DSA:3.20.20.70 4 255 4.4E-108 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS19000 8a3d734528d992619035ff683afb7451 476 Gene3D G3DSA:3.20.20.140 157 339 1.0E-14 T 06-07-2017 LK06_RS19000 8a3d734528d992619035ff683afb7451 476 SMART SM00481 160 224 4.8E-5 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 LK06_RS19000 8a3d734528d992619035ff683afb7451 476 SUPERFAMILY SSF89550 157 366 2.35E-34 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 LK06_RS13640 e0bdb573cf417c4056a8f3398d32aae5 183 Pfam PF01551 Peptidase family M23 70 172 2.3E-32 T 06-07-2017 IPR016047 Peptidase M23 LK06_RS13640 e0bdb573cf417c4056a8f3398d32aae5 183 SUPERFAMILY SSF51261 38 176 1.31E-45 T 06-07-2017 IPR011055 Duplicated hybrid motif LK06_RS13640 e0bdb573cf417c4056a8f3398d32aae5 183 Gene3D G3DSA:2.70.70.10 37 177 4.8E-44 T 06-07-2017 LK06_RS12785 2e02492cbd11efb00f2fec497803ed3d 316 Gene3D G3DSA:3.40.366.10 3 119 9.3E-47 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS12785 2e02492cbd11efb00f2fec497803ed3d 316 Gene3D G3DSA:3.40.366.10 188 297 9.3E-47 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS12785 2e02492cbd11efb00f2fec497803ed3d 316 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 293 4.7E-16 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS12785 2e02492cbd11efb00f2fec497803ed3d 316 Pfam PF00698 Acyl transferase domain 7 282 6.4E-23 T 06-07-2017 IPR014043 Acyl transferase LK06_RS12785 2e02492cbd11efb00f2fec497803ed3d 316 Gene3D G3DSA:3.30.70.250 122 187 7.6E-17 T 06-07-2017 LK06_RS12785 2e02492cbd11efb00f2fec497803ed3d 316 SUPERFAMILY SSF55048 127 176 2.22E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS12785 2e02492cbd11efb00f2fec497803ed3d 316 SUPERFAMILY SSF52151 181 300 2.46E-56 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS12785 2e02492cbd11efb00f2fec497803ed3d 316 SUPERFAMILY SSF52151 1 119 2.46E-56 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS06555 9a7ab1a6cf5db039daeefe448ba2cd5c 260 Gene3D G3DSA:3.40.50.1360 4 250 5.9E-74 T 06-07-2017 LK06_RS06555 9a7ab1a6cf5db039daeefe448ba2cd5c 260 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 250 4.7E-78 T 06-07-2017 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 LK06_RS06555 9a7ab1a6cf5db039daeefe448ba2cd5c 260 SUPERFAMILY SSF100950 6 255 1.81E-62 T 06-07-2017 LK06_RS06555 9a7ab1a6cf5db039daeefe448ba2cd5c 260 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 240 4.6E-73 T 06-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 SUPERFAMILY SSF46557 8 81 3.4E-23 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 PIRSF PIRSF006092 3 164 3.4E-35 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 53 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 125 141 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 161 6.5E-14 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 SUPERFAMILY SSF54534 85 160 4.32E-11 T 06-07-2017 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 Pfam PF03449 Transcription elongation factor, N-terminal 10 79 3.9E-25 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 10 160 5.0E-46 T 06-07-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 161 28.671 T 06-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 Gene3D G3DSA:1.10.287.180 7 79 3.9E-27 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 LK06_RS20995 f32f76c89f01899507cde3c2e660493c 165 Gene3D G3DSA:3.10.50.30 81 162 1.6E-15 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 SUPERFAMILY SSF158472 173 221 5.89E-6 T 06-07-2017 LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 336 434 5.2E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 SMART SM00304 172 224 1.6E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 SMART SM00388 225 283 8.5E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 SUPERFAMILY SSF55874 294 432 1.83E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 414 3.1E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 3.1E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 Gene3D G3DSA:3.30.565.10 294 432 2.6E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 SUPERFAMILY SSF47384 209 277 2.55E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 274 2.3E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 Pfam PF00672 HAMP domain 153 220 9.6E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 SMART SM00387 331 436 7.9E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS10835 5aeb15f49383621e19c2fac464decaed 467 Gene3D G3DSA:1.10.287.130 215 275 4.7E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 Pfam PF02627 Carboxymuconolactone decarboxylase family 336 418 3.1E-25 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 Gene3D G3DSA:1.20.1290.10 304 426 9.4E-30 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 SUPERFAMILY SSF69118 304 424 1.7E-37 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 SUPERFAMILY SSF53474 5 255 2.83E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 304 423 4.8E-49 T 06-07-2017 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44 LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 7.7E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 7.7E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 7.7E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 7.7E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 Pfam PF00561 alpha/beta hydrolase fold 20 124 1.2E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS27785 bd7a76f80984badf4b7a2545ac78a43d 429 Gene3D G3DSA:3.40.50.1820 5 256 1.8E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS24890 705dcacff16ff41ca83a086752f1d8f9 250 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 43 248 6.0E-51 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS24890 705dcacff16ff41ca83a086752f1d8f9 250 SUPERFAMILY SSF51735 4 135 6.17E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS24890 705dcacff16ff41ca83a086752f1d8f9 250 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 248 28.869 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS24890 705dcacff16ff41ca83a086752f1d8f9 250 SUPERFAMILY SSF55347 109 217 1.16E-38 T 06-07-2017 LK06_RS24890 705dcacff16ff41ca83a086752f1d8f9 250 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 130 147 - T 06-07-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS24890 705dcacff16ff41ca83a086752f1d8f9 250 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 108 1.5E-23 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS24890 705dcacff16ff41ca83a086752f1d8f9 250 PIRSF PIRSF000161 2 250 1.2E-60 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS24890 705dcacff16ff41ca83a086752f1d8f9 250 Gene3D G3DSA:3.40.50.720 3 143 3.3E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS24890 705dcacff16ff41ca83a086752f1d8f9 250 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 111 247 3.2E-27 T 06-07-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS19625 db3074bb023d024efdee76b9667cf59d 741 Pfam PF03176 MMPL family 450 701 7.1E-34 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS19625 db3074bb023d024efdee76b9667cf59d 741 Pfam PF03176 MMPL family 45 372 3.6E-86 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS19625 db3074bb023d024efdee76b9667cf59d 741 SUPERFAMILY SSF82866 133 333 2.35E-33 T 06-07-2017 LK06_RS19625 db3074bb023d024efdee76b9667cf59d 741 Gene3D G3DSA:1.20.1640.10 133 339 5.6E-35 T 06-07-2017 LK06_RS19625 db3074bb023d024efdee76b9667cf59d 741 Gene3D G3DSA:1.20.1640.10 480 706 6.9E-32 T 06-07-2017 LK06_RS19625 db3074bb023d024efdee76b9667cf59d 741 SUPERFAMILY SSF82866 473 700 2.09E-26 T 06-07-2017 LK06_RS16390 6644d4b521ef9058d4293d76301364d9 150 Gene3D G3DSA:3.90.79.10 4 120 2.6E-32 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS16390 6644d4b521ef9058d4293d76301364d9 150 PRINTS PR00502 NUDIX hydrolase family signature 39 53 6.9E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS16390 6644d4b521ef9058d4293d76301364d9 150 PRINTS PR00502 NUDIX hydrolase family signature 53 68 6.9E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS16390 6644d4b521ef9058d4293d76301364d9 150 SUPERFAMILY SSF55811 8 133 4.2E-32 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS16390 6644d4b521ef9058d4293d76301364d9 150 Pfam PF00293 NUDIX domain 14 119 1.7E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS16390 6644d4b521ef9058d4293d76301364d9 150 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS16995 5a73a1f88df4555d7d029142e5b31573 312 Gene3D G3DSA:3.40.50.300 4 225 8.6E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16995 5a73a1f88df4555d7d029142e5b31573 312 SMART SM00382 35 213 1.6E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS16995 5a73a1f88df4555d7d029142e5b31573 312 Pfam PF00005 ABC transporter 27 164 9.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS16995 5a73a1f88df4555d7d029142e5b31573 312 SUPERFAMILY SSF52540 7 225 7.11E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16995 5a73a1f88df4555d7d029142e5b31573 312 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Gene3D G3DSA:1.10.460.10 156 203 1.9E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Gene3D G3DSA:1.10.460.10 501 595 1.9E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 SUPERFAMILY SSF56712 12 595 1.83E-182 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Gene3D G3DSA:3.40.50.140 12 155 3.6E-49 T 06-07-2017 IPR006171 Toprim domain LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 14 660 3.7E-245 T 06-07-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 324 338 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 SMART SM00436 125 213 8.8E-46 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 329 338 1.0E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 517 531 1.0E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 1.0E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 406 422 1.0E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 183 201 1.0E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Pfam PF01751 Toprim domain 14 134 8.4E-28 T 06-07-2017 IPR006171 Toprim domain LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Hamap MF_00952 DNA topoisomerase 1 [topA]. 12 778 56.356 T 06-07-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Pfam PF13368 Topoisomerase C-terminal repeat 832 884 1.1E-20 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Pfam PF13368 Topoisomerase C-terminal repeat 642 691 4.8E-8 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Pfam PF13368 Topoisomerase C-terminal repeat 699 763 1.4E-14 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Pfam PF13368 Topoisomerase C-terminal repeat 769 819 6.7E-14 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Pfam PF01131 DNA topoisomerase 149 591 3.3E-132 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 SMART SM00493 12 125 2.5E-35 T 06-07-2017 IPR006171 Toprim domain LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Gene3D G3DSA:2.70.20.10 354 500 1.8E-34 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 Gene3D G3DSA:2.70.20.10 205 353 6.0E-27 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 LK06_RS13990 a14db8b057a43a68730283d0bd0d0066 952 SMART SM00437 287 554 3.7E-122 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 LK06_RS03665 378bca5952c7785aaa4223c57b6875a6 202 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS03665 378bca5952c7785aaa4223c57b6875a6 202 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 85 6.3E-15 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS03665 378bca5952c7785aaa4223c57b6875a6 202 PIRSF PIRSF000847 11 202 2.6E-43 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 LK06_RS16070 e6650ca6dec199005e717aad2d054893 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 151 2.1E-46 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily LK06_RS16070 e6650ca6dec199005e717aad2d054893 163 Gene3D G3DSA:3.40.50.270 1 157 4.3E-53 T 06-07-2017 LK06_RS16070 e6650ca6dec199005e717aad2d054893 163 SMART SM00226 3 153 1.4E-53 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily LK06_RS16070 e6650ca6dec199005e717aad2d054893 163 SUPERFAMILY SSF52788 1 153 1.24E-47 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily LK06_RS16070 e6650ca6dec199005e717aad2d054893 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 6.0E-25 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 LK06_RS16070 e6650ca6dec199005e717aad2d054893 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 125 140 6.0E-25 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 LK06_RS16070 e6650ca6dec199005e717aad2d054893 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 105 118 6.0E-25 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 LK06_RS16070 e6650ca6dec199005e717aad2d054893 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 48 64 6.0E-25 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 LK06_RS16070 e6650ca6dec199005e717aad2d054893 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 6.0E-25 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 LK06_RS14315 4b9f5bf54bfc1cbf8d77e780ddd806a3 183 Gene3D G3DSA:2.60.40.1260 67 160 4.7E-13 T 06-07-2017 IPR001322 Lamin Tail Domain LK06_RS14315 4b9f5bf54bfc1cbf8d77e780ddd806a3 183 Pfam PF00932 Lamin Tail Domain 45 157 6.3E-16 T 06-07-2017 IPR001322 Lamin Tail Domain LK06_RS14315 4b9f5bf54bfc1cbf8d77e780ddd806a3 183 SUPERFAMILY SSF74853 32 159 4.97E-16 T 06-07-2017 IPR001322 Lamin Tail Domain LK06_RS27680 8d72d569e4685d060f617e1c5f3e78cb 403 Gene3D G3DSA:1.20.140.10 221 397 1.1E-34 T 06-07-2017 LK06_RS27680 8d72d569e4685d060f617e1c5f3e78cb 403 Gene3D G3DSA:1.10.540.10 18 124 9.8E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS27680 8d72d569e4685d060f617e1c5f3e78cb 403 SUPERFAMILY SSF56645 25 227 2.36E-31 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS27680 8d72d569e4685d060f617e1c5f3e78cb 403 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 256 383 4.2E-25 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain LK06_RS27680 8d72d569e4685d060f617e1c5f3e78cb 403 SUPERFAMILY SSF47203 249 396 2.47E-13 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS27680 8d72d569e4685d060f617e1c5f3e78cb 403 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 33 107 3.5E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS27680 8d72d569e4685d060f617e1c5f3e78cb 403 Gene3D G3DSA:2.40.110.10 130 220 1.6E-26 T 06-07-2017 LK06_RS27680 8d72d569e4685d060f617e1c5f3e78cb 403 PIRSF PIRSF016578 14 400 1.3E-88 T 06-07-2017 LK06_RS05320 dc4bc8994bdf9701a6caeb93a763c9f7 153 Gene3D G3DSA:1.10.1660.10 65 134 1.8E-16 T 06-07-2017 LK06_RS05320 dc4bc8994bdf9701a6caeb93a763c9f7 153 Gene3D G3DSA:1.10.1660.10 11 64 1.8E-19 T 06-07-2017 LK06_RS05320 dc4bc8994bdf9701a6caeb93a763c9f7 153 SMART SM00422 11 79 5.3E-24 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS05320 dc4bc8994bdf9701a6caeb93a763c9f7 153 SUPERFAMILY SSF46955 11 132 3.66E-28 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS05320 dc4bc8994bdf9701a6caeb93a763c9f7 153 Pfam PF09278 MerR, DNA binding 53 118 3.6E-18 T 06-07-2017 IPR015358 Transcription regulator MerR, DNA binding LK06_RS05320 dc4bc8994bdf9701a6caeb93a763c9f7 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 1.3E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS05320 dc4bc8994bdf9701a6caeb93a763c9f7 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 1.3E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS05320 dc4bc8994bdf9701a6caeb93a763c9f7 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 1.3E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS05320 dc4bc8994bdf9701a6caeb93a763c9f7 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 150 4.2E-72 T 06-07-2017 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 LK06_RS05320 dc4bc8994bdf9701a6caeb93a763c9f7 153 Pfam PF00376 MerR family regulatory protein 12 48 2.8E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS28020 d9bac91c1eb896e44fb3182ea1ace389 147 SUPERFAMILY SSF55961 5 135 7.57E-22 T 06-07-2017 LK06_RS28020 d9bac91c1eb896e44fb3182ea1ace389 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 146 5.1E-25 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase LK06_RS28020 d9bac91c1eb896e44fb3182ea1ace389 147 PIRSF PIRSF017371 1 147 2.3E-74 T 06-07-2017 IPR014488 Uncharacterised conserved protein UCP017371 LK06_RS28020 d9bac91c1eb896e44fb3182ea1ace389 147 Gene3D G3DSA:3.30.530.20 4 112 4.1E-8 T 06-07-2017 IPR023393 START-like domain LK06_RS25040 698642296e7ef0929ffe7be920688314 373 SUPERFAMILY SSF54752 269 327 2.09E-21 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal LK06_RS25040 698642296e7ef0929ffe7be920688314 373 SMART SM00382 58 229 3.9E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS25040 698642296e7ef0929ffe7be920688314 373 Gene3D G3DSA:3.40.50.300 29 268 3.9E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25040 698642296e7ef0929ffe7be920688314 373 Pfam PF00154 recA bacterial DNA recombination protein 8 269 8.6E-144 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LK06_RS25040 698642296e7ef0929ffe7be920688314 373 Hamap MF_00268 Protein RecA [recA]. 6 330 53.095 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LK06_RS25040 698642296e7ef0929ffe7be920688314 373 Gene3D G3DSA:3.30.250.10 269 327 1.6E-29 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal LK06_RS25040 698642296e7ef0929ffe7be920688314 373 SUPERFAMILY SSF52540 5 268 3.52E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25040 698642296e7ef0929ffe7be920688314 373 PRINTS PR00142 RecA protein signature 298 315 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LK06_RS25040 698642296e7ef0929ffe7be920688314 373 PRINTS PR00142 RecA protein signature 128 157 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LK06_RS25040 698642296e7ef0929ffe7be920688314 373 PRINTS PR00142 RecA protein signature 166 195 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LK06_RS25040 698642296e7ef0929ffe7be920688314 373 PRINTS PR00142 RecA protein signature 211 239 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LK06_RS25040 698642296e7ef0929ffe7be920688314 373 PRINTS PR00142 RecA protein signature 94 123 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LK06_RS25040 698642296e7ef0929ffe7be920688314 373 PRINTS PR00142 RecA protein signature 244 273 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LK06_RS25040 698642296e7ef0929ffe7be920688314 373 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 325 5.2E-176 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LK06_RS25040 698642296e7ef0929ffe7be920688314 373 ProSitePatterns PS00321 recA signature. 214 222 - T 06-07-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 LK06_RS08975 d84d429b04665f441c0445931e67f42b 367 Pfam PF13407 Periplasmic binding protein domain 41 303 6.3E-61 T 06-07-2017 IPR025997 Periplasmic binding protein LK06_RS08975 d84d429b04665f441c0445931e67f42b 367 Gene3D G3DSA:3.40.50.2300 155 339 1.1E-35 T 06-07-2017 LK06_RS08975 d84d429b04665f441c0445931e67f42b 367 SUPERFAMILY SSF53822 38 306 8.17E-57 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS08975 d84d429b04665f441c0445931e67f42b 367 Gene3D G3DSA:3.40.50.2300 40 154 1.3E-24 T 06-07-2017 LK06_RS23610 5e3c2048683edb5acfc20d477da6cf8f 118 Gene3D G3DSA:3.40.30.10 16 117 8.8E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS23610 5e3c2048683edb5acfc20d477da6cf8f 118 Pfam PF00085 Thioredoxin 17 115 3.3E-26 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 LK06_RS23610 5e3c2048683edb5acfc20d477da6cf8f 118 ProSitePatterns PS00194 Thioredoxin family active site. 35 53 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 LK06_RS23610 5e3c2048683edb5acfc20d477da6cf8f 118 SUPERFAMILY SSF52833 8 118 4.63E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS23610 5e3c2048683edb5acfc20d477da6cf8f 118 PRINTS PR00421 Thioredoxin family signature 82 93 3.6E-7 T 06-07-2017 LK06_RS23610 5e3c2048683edb5acfc20d477da6cf8f 118 PRINTS PR00421 Thioredoxin family signature 34 42 3.6E-7 T 06-07-2017 LK06_RS23610 5e3c2048683edb5acfc20d477da6cf8f 118 PRINTS PR00421 Thioredoxin family signature 42 51 3.6E-7 T 06-07-2017 LK06_RS23610 5e3c2048683edb5acfc20d477da6cf8f 118 TIGRFAM TIGR01068 thioredoxin: thioredoxin 19 116 3.4E-29 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LK06_RS23610 5e3c2048683edb5acfc20d477da6cf8f 118 PIRSF PIRSF000077 13 118 3.2E-34 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LK06_RS15045 fc13b923a4d0edb89d3bcbf18016d22e 206 SUPERFAMILY SSF46689 13 95 1.7E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS15045 fc13b923a4d0edb89d3bcbf18016d22e 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 1.4E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS15045 fc13b923a4d0edb89d3bcbf18016d22e 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS15045 fc13b923a4d0edb89d3bcbf18016d22e 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS15045 fc13b923a4d0edb89d3bcbf18016d22e 206 SUPERFAMILY SSF48498 92 195 1.21E-11 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS15045 fc13b923a4d0edb89d3bcbf18016d22e 206 Gene3D G3DSA:1.10.357.10 14 200 1.1E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS29595 6d771e93662941e23309e9b004295bef 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 LK06_RS29595 6d771e93662941e23309e9b004295bef 507 Pfam PF00171 Aldehyde dehydrogenase family 36 495 4.8E-162 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS29595 6d771e93662941e23309e9b004295bef 507 Gene3D G3DSA:3.40.605.10 19 270 7.2E-93 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS29595 6d771e93662941e23309e9b004295bef 507 SUPERFAMILY SSF53720 13 499 5.24E-162 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS29595 6d771e93662941e23309e9b004295bef 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 LK06_RS29595 6d771e93662941e23309e9b004295bef 507 Gene3D G3DSA:3.40.309.10 271 470 7.1E-58 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 SMART SM00331 495 709 2.4E-31 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 Pfam PF08448 PAS fold 197 279 1.6E-5 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 Pfam PF13185 GAF domain 330 468 5.5E-13 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 SUPERFAMILY SSF55781 331 480 7.85E-16 T 06-07-2017 IPR029016 GAF domain-like LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 Gene3D G3DSA:3.30.450.20 192 260 1.3E-12 T 06-07-2017 LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 SMART SM00065 329 477 5.8E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 SUPERFAMILY SSF55785 194 277 8.03E-13 T 06-07-2017 IPR000014 PAS domain LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 SUPERFAMILY SSF81606 512 708 4.18E-7 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 528 709 5.5E-47 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 Gene3D G3DSA:3.30.450.40 319 470 8.2E-14 T 06-07-2017 IPR029016 GAF domain-like LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 SMART SM00091 190 256 1.2E-4 T 06-07-2017 IPR000014 PAS domain LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 SUPERFAMILY SSF55781 22 163 4.32E-9 T 06-07-2017 IPR029016 GAF domain-like LK06_RS01030 aec6df799e42b44aa9bbff21f6856074 713 Gene3D G3DSA:3.30.450.40 16 162 2.6E-5 T 06-07-2017 IPR029016 GAF domain-like LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 Pfam PF00586 AIR synthase related protein, N-terminal domain 99 201 1.0E-22 T 06-07-2017 IPR016188 PurM-like, N-terminal domain LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 Pfam PF00586 AIR synthase related protein, N-terminal domain 471 575 9.0E-24 T 06-07-2017 IPR016188 PurM-like, N-terminal domain LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 SUPERFAMILY SSF55326 411 581 5.63E-55 T 06-07-2017 LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 752 311.218 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 SUPERFAMILY SSF56042 586 750 9.57E-39 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 PIRSF PIRSF001587 8 752 1.6E-291 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 27 750 7.1E-265 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 SUPERFAMILY SSF56042 212 442 2.84E-52 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 Pfam PF02769 AIR synthase related protein, C-terminal domain 214 369 1.9E-33 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 Pfam PF02769 AIR synthase related protein, C-terminal domain 588 725 6.1E-19 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 SUPERFAMILY SSF55326 22 207 3.74E-50 T 06-07-2017 LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 Gene3D G3DSA:3.30.1330.10 430 578 6.1E-56 T 06-07-2017 IPR016188 PurM-like, N-terminal domain LK06_RS17025 1d856a493c58489deca9a0fb588d9587 752 Gene3D G3DSA:3.30.1330.10 59 206 3.3E-51 T 06-07-2017 IPR016188 PurM-like, N-terminal domain LK06_RS22465 5893994d09707392cd2a63a850aabd14 322 Pfam PF00781 Diacylglycerol kinase catalytic domain 2 119 8.7E-27 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 LK06_RS22465 5893994d09707392cd2a63a850aabd14 322 Gene3D G3DSA:3.40.50.10330 35 77 9.0E-5 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 LK06_RS22465 5893994d09707392cd2a63a850aabd14 322 SUPERFAMILY SSF111331 1 322 3.53E-52 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain LK06_RS22465 5893994d09707392cd2a63a850aabd14 322 SMART SM00046 2 133 3.7E-10 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 LK06_RS16710 355dc98cd2c51c048a654f4707d58d00 211 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 210 43.447 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 LK06_RS16710 355dc98cd2c51c048a654f4707d58d00 211 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 8.4E-76 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 LK06_RS16710 355dc98cd2c51c048a654f4707d58d00 211 Pfam PF14681 Uracil phosphoribosyltransferase 5 209 3.2E-64 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS16710 355dc98cd2c51c048a654f4707d58d00 211 Gene3D G3DSA:3.40.50.2020 2 208 5.2E-73 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS16710 355dc98cd2c51c048a654f4707d58d00 211 SUPERFAMILY SSF53271 3 208 2.88E-64 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS04145 24c59d55997b1854ab3666dc624c8930 144 SUPERFAMILY SSF48013 4 132 9.94E-40 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 LK06_RS04145 24c59d55997b1854ab3666dc624c8930 144 Gene3D G3DSA:1.10.940.10 2 132 9.3E-43 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 LK06_RS04145 24c59d55997b1854ab3666dc624c8930 144 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 133 1.3E-38 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 LK06_RS04145 24c59d55997b1854ab3666dc624c8930 144 Pfam PF01029 NusB family 6 132 1.7E-34 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 LK06_RS04145 24c59d55997b1854ab3666dc624c8930 144 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 137 22.348 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 LK06_RS30585 c3ca02a2b5b0fff4c49d7a71904b8bcd 536 Gene3D G3DSA:3.30.300.30 434 531 6.7E-27 T 06-07-2017 LK06_RS30585 c3ca02a2b5b0fff4c49d7a71904b8bcd 536 SUPERFAMILY SSF56801 4 533 9.42E-110 T 06-07-2017 LK06_RS30585 c3ca02a2b5b0fff4c49d7a71904b8bcd 536 Pfam PF00501 AMP-binding enzyme 9 436 2.4E-60 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS30585 c3ca02a2b5b0fff4c49d7a71904b8bcd 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 522 1.9E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS30585 c3ca02a2b5b0fff4c49d7a71904b8bcd 536 Gene3D G3DSA:3.40.50.980 4 179 1.1E-33 T 06-07-2017 LK06_RS30585 c3ca02a2b5b0fff4c49d7a71904b8bcd 536 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS30585 c3ca02a2b5b0fff4c49d7a71904b8bcd 536 Gene3D G3DSA:2.30.38.10 359 430 1.1E-11 T 06-07-2017 LK06_RS30585 c3ca02a2b5b0fff4c49d7a71904b8bcd 536 Gene3D G3DSA:3.40.50.980 180 347 1.1E-17 T 06-07-2017 LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 Gene3D G3DSA:1.10.357.10 82 223 6.5E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 5.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 5.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 4.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 79 222 1.0E-21 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 SUPERFAMILY SSF48498 84 224 3.0E-35 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 PRINTS PR00400 Tetracycline repressor protein signature 141 160 2.0E-9 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 PRINTS PR00400 Tetracycline repressor protein signature 85 104 2.0E-9 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 PRINTS PR00400 Tetracycline repressor protein signature 34 57 2.0E-9 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 Gene3D G3DSA:1.10.10.60 6 77 5.5E-26 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS27470 a9bd5a3260cf71d72eb67717a1d06d82 228 SUPERFAMILY SSF46689 11 75 2.21E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS15470 af9aeb8624f8f69741d13c8c32eb4824 563 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 7 563 1.6E-299 T 06-07-2017 IPR011975 Phenylacetic acid degradation protein PaaN2 LK06_RS15470 af9aeb8624f8f69741d13c8c32eb4824 563 Pfam PF00171 Aldehyde dehydrogenase family 93 535 5.9E-33 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS15470 af9aeb8624f8f69741d13c8c32eb4824 563 SUPERFAMILY SSF53720 72 539 6.68E-58 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS15470 af9aeb8624f8f69741d13c8c32eb4824 563 Gene3D G3DSA:3.40.605.10 93 327 8.3E-28 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS15470 af9aeb8624f8f69741d13c8c32eb4824 563 Gene3D G3DSA:3.40.309.10 328 524 4.9E-29 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 SMART SM00421 154 211 6.1E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 1.6E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 SMART SM00448 2 115 2.4E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 Gene3D G3DSA:3.40.50.2300 3 123 4.9E-38 T 06-07-2017 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 SUPERFAMILY SSF46894 148 217 1.19E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.4E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.4E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.4E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 Pfam PF00072 Response regulator receiver domain 4 115 4.6E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 SUPERFAMILY SSF52172 3 133 7.54E-35 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS18155 25b7da0b944e030d42fb4d52503464a7 222 Gene3D G3DSA:1.10.10.10 124 218 7.5E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11690 22e01de929399c61243e56597cc28f49 748 SUPERFAMILY SSF53448 1 104 5.77E-7 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11690 22e01de929399c61243e56597cc28f49 748 Gene3D G3DSA:3.90.550.10 2 93 4.2E-4 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11690 22e01de929399c61243e56597cc28f49 748 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 356 720 6.6E-130 T 06-07-2017 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 LK06_RS11690 22e01de929399c61243e56597cc28f49 748 SUPERFAMILY SSF53756 503 719 4.08E-10 T 06-07-2017 LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 SUPERFAMILY SSF47413 3 49 1.06E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 Gene3D G3DSA:3.40.50.2300 51 176 2.3E-31 T 06-07-2017 LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 7.2E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 7.2E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 SUPERFAMILY SSF53822 59 338 4.91E-67 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 4.4E-14 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 SMART SM00354 2 69 3.1E-23 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 Gene3D G3DSA:3.40.50.2300 177 314 1.3E-47 T 06-07-2017 LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 Gene3D G3DSA:1.10.260.40 4 47 6.5E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 Pfam PF13377 Periplasmic binding protein-like domain 171 334 5.2E-38 T 06-07-2017 LK06_RS08120 eb89c78a364786fa216aa5dd71857c53 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 06-07-2017 LK06_RS31700 c8681661d3ffa9270b0cbe6a45907d8e 290 Gene3D G3DSA:3.40.47.10 64 163 2.9E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31700 c8681661d3ffa9270b0cbe6a45907d8e 290 SUPERFAMILY SSF53901 57 168 4.61E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28605 d73087b4f12ead0070f8fea96ddb70d5 392 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 14 137 1.9E-14 T 06-07-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 LK06_RS28605 d73087b4f12ead0070f8fea96ddb70d5 392 Gene3D G3DSA:3.40.50.720 14 171 5.2E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28605 d73087b4f12ead0070f8fea96ddb70d5 392 SUPERFAMILY SSF51735 13 161 6.19E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS09405 b9db3dfd0c63d39a09c25169aaa3e82f 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 06-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 LK06_RS09405 b9db3dfd0c63d39a09c25169aaa3e82f 112 PIRSF PIRSF039144 1 112 3.8E-51 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS09405 b9db3dfd0c63d39a09c25169aaa3e82f 112 SMART SM00938 4 105 4.7E-57 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS09405 b9db3dfd0c63d39a09c25169aaa3e82f 112 Gene3D G3DSA:3.30.70.120 1 112 4.0E-46 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal LK06_RS09405 b9db3dfd0c63d39a09c25169aaa3e82f 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 6.4E-40 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS09405 b9db3dfd0c63d39a09c25169aaa3e82f 112 PRINTS PR00340 P-II protein signature 52 75 1.6E-36 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS09405 b9db3dfd0c63d39a09c25169aaa3e82f 112 PRINTS PR00340 P-II protein signature 83 103 1.6E-36 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS09405 b9db3dfd0c63d39a09c25169aaa3e82f 112 PRINTS PR00340 P-II protein signature 2 17 1.6E-36 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS09405 b9db3dfd0c63d39a09c25169aaa3e82f 112 PRINTS PR00340 P-II protein signature 23 41 1.6E-36 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS09405 b9db3dfd0c63d39a09c25169aaa3e82f 112 SUPERFAMILY SSF54913 1 112 1.49E-42 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta LK06_RS24165 24a56e04985f9e1c0d528a165657dc7c 214 SUPERFAMILY SSF46955 1 90 4.49E-14 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS24165 24a56e04985f9e1c0d528a165657dc7c 214 Pfam PF13411 MerR HTH family regulatory protein 1 68 8.2E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS24165 24a56e04985f9e1c0d528a165657dc7c 214 Gene3D G3DSA:1.10.1660.10 1 76 4.9E-16 T 06-07-2017 LK06_RS24165 24a56e04985f9e1c0d528a165657dc7c 214 SMART SM00422 1 71 1.8E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS24165 24a56e04985f9e1c0d528a165657dc7c 214 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.9E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS24165 24a56e04985f9e1c0d528a165657dc7c 214 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.9E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS24165 24a56e04985f9e1c0d528a165657dc7c 214 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.9E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS06120 dc9e1e1fd5bf90272e29cec770cc87f2 319 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 15 170 1.6E-24 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS06120 dc9e1e1fd5bf90272e29cec770cc87f2 319 Gene3D G3DSA:3.30.420.10 12 174 8.6E-45 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS06120 dc9e1e1fd5bf90272e29cec770cc87f2 319 SUPERFAMILY SSF52113 239 311 2.88E-10 T 06-07-2017 IPR001357 BRCT domain LK06_RS06120 dc9e1e1fd5bf90272e29cec770cc87f2 319 Gene3D G3DSA:3.40.50.10190 239 313 2.1E-10 T 06-07-2017 IPR001357 BRCT domain LK06_RS06120 dc9e1e1fd5bf90272e29cec770cc87f2 319 SMART SM00479 14 178 1.1E-33 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III LK06_RS06120 dc9e1e1fd5bf90272e29cec770cc87f2 319 Pfam PF00929 Exonuclease 17 169 7.0E-23 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III LK06_RS06120 dc9e1e1fd5bf90272e29cec770cc87f2 319 SMART SM00292 236 314 0.0014 T 06-07-2017 IPR001357 BRCT domain LK06_RS06120 dc9e1e1fd5bf90272e29cec770cc87f2 319 SUPERFAMILY SSF53098 10 175 2.97E-42 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS04855 a1e15708840d9a7a062bf78506b84c3f 400 SUPERFAMILY SSF51419 26 272 1.14E-22 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS04855 a1e15708840d9a7a062bf78506b84c3f 400 Gene3D G3DSA:3.20.20.10 28 192 4.0E-6 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS04855 a1e15708840d9a7a062bf78506b84c3f 400 Pfam PF01168 Alanine racemase, N-terminal domain 25 273 5.7E-16 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 3.2E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 3.2E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 3.2E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 SUPERFAMILY SSF46955 3 109 1.72E-28 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 Pfam PF13411 MerR HTH family regulatory protein 3 70 2.0E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 Pfam PF07739 TipAS antibiotic-recognition domain 136 251 1.5E-39 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 Gene3D G3DSA:1.10.1660.10 3 57 3.6E-24 T 06-07-2017 LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 Gene3D G3DSA:1.10.1660.10 58 110 3.7E-11 T 06-07-2017 LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 SUPERFAMILY SSF89082 165 256 1.44E-30 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 SMART SM00422 3 72 2.0E-31 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS13845 11a5c2d6f167cd45a125525f7c4c81bd 258 Gene3D G3DSA:1.10.490.50 165 256 1.2E-34 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain LK06_RS01535 4516febb1d9afb1b3539316096607890 433 Pfam PF12867 DinB superfamily 14 144 1.8E-27 T 06-07-2017 IPR024775 DinB-like domain LK06_RS01535 4516febb1d9afb1b3539316096607890 433 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 12 428 2.2E-139 T 06-07-2017 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 LK06_RS01535 4516febb1d9afb1b3539316096607890 433 Gene3D G3DSA:1.20.120.450 8 117 1.9E-7 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase LK06_RS01535 4516febb1d9afb1b3539316096607890 433 SUPERFAMILY SSF56436 170 430 1.72E-76 T 06-07-2017 IPR016187 C-type lectin fold LK06_RS01535 4516febb1d9afb1b3539316096607890 433 Pfam PF03781 Sulfatase-modifying factor enzyme 1 171 429 1.8E-66 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 LK06_RS01535 4516febb1d9afb1b3539316096607890 433 Gene3D G3DSA:3.90.1580.10 169 430 2.8E-76 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 LK06_RS01535 4516febb1d9afb1b3539316096607890 433 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 431 52.041 T 06-07-2017 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 LK06_RS01535 4516febb1d9afb1b3539316096607890 433 SUPERFAMILY SSF109854 6 140 5.04E-20 T 06-07-2017 LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 Pfam PF00989 PAS fold 11 106 1.5E-5 T 06-07-2017 IPR013767 PAS fold GO:0006355 LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 Pfam PF00989 PAS fold 151 262 9.9E-13 T 06-07-2017 IPR013767 PAS fold GO:0006355 LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 SMART SM00091 147 213 2.7E-6 T 06-07-2017 IPR000014 PAS domain LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 SMART SM00091 10 76 4.1E-6 T 06-07-2017 IPR000014 PAS domain LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 Gene3D G3DSA:3.30.450.20 142 262 1.1E-22 T 06-07-2017 LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 150 259 6.7E-8 T 06-07-2017 IPR000014 PAS domain LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 113 3.0E-7 T 06-07-2017 IPR000014 PAS domain LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 Pfam PF00072 Response regulator receiver domain 1505 1612 4.5E-6 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 SUPERFAMILY SSF55785 10 107 6.81E-11 T 06-07-2017 IPR000014 PAS domain LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 SMART SM00448 1503 1616 0.0017 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 SUPERFAMILY SSF55785 137 262 9.95E-19 T 06-07-2017 IPR000014 PAS domain LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 Gene3D G3DSA:3.40.50.2300 1501 1622 2.3E-12 T 06-07-2017 LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 SUPERFAMILY SSF52172 1500 1622 9.25E-14 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS16510 8020ce3cf79f8c2f681dff31f864b47b 1626 Gene3D G3DSA:3.30.450.20 10 113 3.5E-12 T 06-07-2017 LK06_RS24355 274db68d05005a70871e955c918bef3f 331 SUPERFAMILY SSF51679 15 323 4.58E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS24355 274db68d05005a70871e955c918bef3f 331 Pfam PF00296 Luciferase-like monooxygenase 14 254 2.4E-37 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS24355 274db68d05005a70871e955c918bef3f 331 Gene3D G3DSA:3.20.20.30 7 327 1.6E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS11055 05eddaadc735316a6d25fd823f2d20d4 241 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 28 239 5.2E-36 T 06-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal LK06_RS11055 05eddaadc735316a6d25fd823f2d20d4 241 Pfam PF02096 60Kd inner membrane protein 29 239 1.2E-32 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 LK06_RS07070 8a856da1e4175ab6529af8c0b6006390 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 64 390 1.1E-52 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS07070 8a856da1e4175ab6529af8c0b6006390 427 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 19 401 3.4E-182 T 06-07-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LK06_RS07070 8a856da1e4175ab6529af8c0b6006390 427 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 14 403 50.95 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LK06_RS07070 8a856da1e4175ab6529af8c0b6006390 427 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 93 107 - T 06-07-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LK06_RS07070 8a856da1e4175ab6529af8c0b6006390 427 PIRSF PIRSF001413 8 407 3.9E-157 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LK06_RS07070 8a856da1e4175ab6529af8c0b6006390 427 Gene3D G3DSA:3.40.50.1100 111 189 1.7E-22 T 06-07-2017 LK06_RS07070 8a856da1e4175ab6529af8c0b6006390 427 SUPERFAMILY SSF53686 15 402 2.88E-146 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS07070 8a856da1e4175ab6529af8c0b6006390 427 Gene3D G3DSA:3.40.50.1100 190 404 1.4E-99 T 06-07-2017 LK06_RS09950 551f59977254a8a5d1c852b1fb2662c0 390 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 201 382 9.0E-30 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS09950 551f59977254a8a5d1c852b1fb2662c0 390 SMART SM00331 174 383 4.6E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 397 1.8E-38 T 06-07-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 SUPERFAMILY SSF56327 163 418 5.78E-61 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 3.4E-33 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 3.4E-33 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 3.4E-33 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 185 197 3.4E-33 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 3.4E-33 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 3.4E-33 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 SUPERFAMILY SSF51735 1 156 1.45E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS10130 320c37450172daba49364d89fdc12df3 421 Gene3D G3DSA:3.90.110.10 162 418 3.0E-82 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 Pfam PF02056 Family 4 glycosyl hydrolase 2 179 3.0E-45 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS10130 320c37450172daba49364d89fdc12df3 421 Gene3D G3DSA:3.40.50.720 1 158 3.3E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12190 9e8099bb3e77b37b7e5e1ca1a60f9c85 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12190 9e8099bb3e77b37b7e5e1ca1a60f9c85 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 2.0E-9 T 06-07-2017 LK06_RS12190 9e8099bb3e77b37b7e5e1ca1a60f9c85 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 18.304 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12190 9e8099bb3e77b37b7e5e1ca1a60f9c85 37 SUPERFAMILY SSF57840 1 37 1.22E-17 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12190 9e8099bb3e77b37b7e5e1ca1a60f9c85 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 8.3E-22 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12190 9e8099bb3e77b37b7e5e1ca1a60f9c85 37 Pfam PF00444 Ribosomal protein L36 1 37 2.4E-19 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS29580 4b8f6a8a94055c25ba98eb79197e09d1 168 SUPERFAMILY SSF55729 17 155 4.53E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS29580 4b8f6a8a94055c25ba98eb79197e09d1 168 Gene3D G3DSA:3.40.630.30 16 162 4.7E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS29580 4b8f6a8a94055c25ba98eb79197e09d1 168 Pfam PF13673 Acetyltransferase (GNAT) domain 64 146 4.2E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS01260 c56352e2a183f52ddaba42ca18b659ab 200 Gene3D G3DSA:1.10.357.10 7 199 1.5E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS01260 c56352e2a183f52ddaba42ca18b659ab 200 SUPERFAMILY SSF46689 9 81 6.98E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01260 c56352e2a183f52ddaba42ca18b659ab 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 8.2E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01260 c56352e2a183f52ddaba42ca18b659ab 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 3.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01260 c56352e2a183f52ddaba42ca18b659ab 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 3.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS15685 7022796a8d4cb7b9decbeba4e533f951 182 Gene3D G3DSA:1.10.260.40 25 62 2.0E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS15685 7022796a8d4cb7b9decbeba4e533f951 182 SUPERFAMILY SSF47413 22 64 9.5E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 16 292 1.0E-103 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 12 292 48.19 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 Pfam PF00551 Formyl transferase 98 274 1.2E-37 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 SUPERFAMILY SSF53328 98 292 6.67E-63 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 Pfam PF13740 ACT domain 16 70 1.9E-5 T 06-07-2017 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 Gene3D G3DSA:3.40.50.170 98 292 3.9E-57 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 PIRSF PIRSF036480 12 293 8.9E-116 T 06-07-2017 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 SUPERFAMILY SSF55021 14 94 7.5E-20 T 06-07-2017 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 17 43 4.1E-51 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 98 120 4.1E-51 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 244 266 4.1E-51 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 120 147 4.1E-51 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 49 61 4.1E-51 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 266 291 4.1E-51 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 LK06_RS18760 943f79dde911e99e158f0c6f8fe99958 293 Gene3D G3DSA:3.30.70.260 12 92 1.2E-30 T 06-07-2017 LK06_RS02920 6e2605aeba024f91c1f288ff4829236d 87 Pfam PF01391 Collagen triple helix repeat (20 copies) 28 86 2.0E-9 T 06-07-2017 IPR008160 Collagen triple helix repeat LK06_RS02920 6e2605aeba024f91c1f288ff4829236d 87 Pfam PF01391 Collagen triple helix repeat (20 copies) 1 55 2.1E-9 T 06-07-2017 IPR008160 Collagen triple helix repeat LK06_RS07945 31ee07bdfb600461fd0dcc8ddce12bd0 342 Gene3D G3DSA:1.10.10.10 7 96 2.7E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS07945 31ee07bdfb600461fd0dcc8ddce12bd0 342 SUPERFAMILY SSF46785 9 92 8.98E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS07945 31ee07bdfb600461fd0dcc8ddce12bd0 342 Pfam PF16864 Dimerisation domain 13 75 6.1E-7 T 06-07-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain LK06_RS07945 31ee07bdfb600461fd0dcc8ddce12bd0 342 PIRSF PIRSF005739 3 340 1.5E-32 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 LK06_RS07945 31ee07bdfb600461fd0dcc8ddce12bd0 342 SUPERFAMILY SSF53335 96 338 8.35E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07945 31ee07bdfb600461fd0dcc8ddce12bd0 342 Pfam PF00891 O-methyltransferase 110 325 3.3E-32 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 LK06_RS07945 31ee07bdfb600461fd0dcc8ddce12bd0 342 Gene3D G3DSA:3.40.50.150 97 338 3.8E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03020 6c9ec58e011b1f00d9ca52513c0848a0 369 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 88 356 7.3E-19 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD LK06_RS20555 78f4e3f517d4dfed29a3918a141e1bae 190 SUPERFAMILY SSF158694 19 165 1.31E-27 T 06-07-2017 LK06_RS20555 78f4e3f517d4dfed29a3918a141e1bae 190 Pfam PF09349 OHCU decarboxylase 97 161 5.7E-10 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 LK06_RS20555 78f4e3f517d4dfed29a3918a141e1bae 190 Gene3D G3DSA:1.10.3330.10 93 166 1.4E-16 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 LK06_RS20555 78f4e3f517d4dfed29a3918a141e1bae 190 Gene3D G3DSA:1.10.3330.10 26 80 5.3E-7 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 LK06_RS23135 a6f044690051ee4bb9677a68a80ca98b 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 425 8.8E-103 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase LK06_RS23135 a6f044690051ee4bb9677a68a80ca98b 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 337 2.4E-33 T 06-07-2017 IPR000477 Reverse transcriptase domain LK06_RS23135 a6f044690051ee4bb9677a68a80ca98b 478 Pfam PF08388 Group II intron, maturase-specific domain 361 437 3.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS23135 a6f044690051ee4bb9677a68a80ca98b 478 SUPERFAMILY SSF56672 2 436 2.0E-48 T 06-07-2017 LK06_RS18095 a6f044690051ee4bb9677a68a80ca98b 478 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 425 8.8E-103 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase LK06_RS18095 a6f044690051ee4bb9677a68a80ca98b 478 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 337 2.4E-33 T 06-07-2017 IPR000477 Reverse transcriptase domain LK06_RS18095 a6f044690051ee4bb9677a68a80ca98b 478 Pfam PF08388 Group II intron, maturase-specific domain 361 437 3.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS18095 a6f044690051ee4bb9677a68a80ca98b 478 SUPERFAMILY SSF56672 2 436 2.0E-48 T 06-07-2017 LK06_RS11205 b1d182020af1bef837b8ec6a2bb7ab5f 688 Gene3D G3DSA:2.60.40.10 455 535 6.6E-12 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS11205 b1d182020af1bef837b8ec6a2bb7ab5f 688 Gene3D G3DSA:3.40.50.200 116 438 2.5E-62 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS11205 b1d182020af1bef837b8ec6a2bb7ab5f 688 SUPERFAMILY SSF49313 454 536 1.26E-13 T 06-07-2017 IPR015919 Cadherin-like GO:0005509|GO:0016020 LK06_RS11205 b1d182020af1bef837b8ec6a2bb7ab5f 688 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 369 379 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site LK06_RS11205 b1d182020af1bef837b8ec6a2bb7ab5f 688 Pfam PF05345 Putative Ig domain 483 523 1.0E-11 T 06-07-2017 IPR008009 Putative Ig LK06_RS11205 b1d182020af1bef837b8ec6a2bb7ab5f 688 SUPERFAMILY SSF52743 114 443 4.58E-43 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS11205 b1d182020af1bef837b8ec6a2bb7ab5f 688 SMART SM00736 452 541 2.6E-6 T 06-07-2017 IPR006644 Dystroglycan-type cadherin-like GO:0016020 LK06_RS13720 de596eeb12d973feee04d54047b84083 233 SMART SM00448 13 126 4.7E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS13720 de596eeb12d973feee04d54047b84083 233 Pfam PF00072 Response regulator receiver domain 15 127 1.9E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS13720 de596eeb12d973feee04d54047b84083 233 Gene3D G3DSA:1.10.10.10 134 228 1.3E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13720 de596eeb12d973feee04d54047b84083 233 SUPERFAMILY SSF52172 13 145 2.42E-34 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS13720 de596eeb12d973feee04d54047b84083 233 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS13720 de596eeb12d973feee04d54047b84083 233 SMART SM00421 164 221 1.1E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS13720 de596eeb12d973feee04d54047b84083 233 Gene3D G3DSA:3.40.50.2300 11 133 1.9E-37 T 06-07-2017 LK06_RS13720 de596eeb12d973feee04d54047b84083 233 SUPERFAMILY SSF46894 158 227 3.27E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS13720 de596eeb12d973feee04d54047b84083 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 221 1.1E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS13720 de596eeb12d973feee04d54047b84083 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 1.4E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS13720 de596eeb12d973feee04d54047b84083 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 1.4E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS13720 de596eeb12d973feee04d54047b84083 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 1.4E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS17890 26a0595025656a1a93867b11f52f073c 313 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 71 148 3.1E-19 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 LK06_RS17890 26a0595025656a1a93867b11f52f073c 313 SMART SM00967 71 148 1.0E-20 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 LK06_RS17890 26a0595025656a1a93867b11f52f073c 313 Gene3D G3DSA:3.30.1330.30 66 144 1.8E-19 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like LK06_RS17890 26a0595025656a1a93867b11f52f073c 313 Gene3D G3DSA:3.40.1280.10 160 312 1.0E-46 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LK06_RS17890 26a0595025656a1a93867b11f52f073c 313 Pfam PF00588 SpoU rRNA Methylase family 165 306 8.6E-32 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 LK06_RS17890 26a0595025656a1a93867b11f52f073c 313 SUPERFAMILY SSF55315 66 145 3.53E-15 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like LK06_RS17890 26a0595025656a1a93867b11f52f073c 313 SUPERFAMILY SSF75217 136 312 3.47E-41 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases LK06_RS17890 26a0595025656a1a93867b11f52f073c 313 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 69 312 1.7E-58 T 06-07-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 LK06_RS07270 ba63a1084ec7a73584e882e613ef6fbf 96 Pfam PF02325 YGGT family 10 89 8.7E-12 T 06-07-2017 IPR003425 CCB3/YggT GO:0016020 LK06_RS00460 55c92ec7df868e66d51a264b29bcd294 483 SUPERFAMILY SSF142921 10 77 3.27E-10 T 06-07-2017 IPR008893 WGR domain LK06_RS00460 55c92ec7df868e66d51a264b29bcd294 483 Gene3D G3DSA:2.20.140.10 11 79 3.9E-23 T 06-07-2017 IPR008893 WGR domain LK06_RS00460 55c92ec7df868e66d51a264b29bcd294 483 SMART SM00773 8 81 2.5E-21 T 06-07-2017 IPR008893 WGR domain LK06_RS00460 55c92ec7df868e66d51a264b29bcd294 483 Pfam PF13360 PQQ-like domain 247 378 5.1E-11 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat LK06_RS00460 55c92ec7df868e66d51a264b29bcd294 483 Gene3D G3DSA:2.140.10.10 200 385 2.0E-14 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS00460 55c92ec7df868e66d51a264b29bcd294 483 Pfam PF05406 WGR domain 10 79 2.4E-17 T 06-07-2017 IPR008893 WGR domain LK06_RS00460 55c92ec7df868e66d51a264b29bcd294 483 SUPERFAMILY SSF50998 193 427 2.04E-20 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS00460 55c92ec7df868e66d51a264b29bcd294 483 SUPERFAMILY SSF50998 105 165 2.04E-20 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS00460 55c92ec7df868e66d51a264b29bcd294 483 Gene3D G3DSA:2.140.10.10 104 176 3.5E-6 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 SUPERFAMILY SSF69322 291 407 4.58E-18 T 06-07-2017 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 SUPERFAMILY SSF69322 437 563 4.58E-18 T 06-07-2017 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Gene3D G3DSA:2.130.10.10 249 276 2.1E-86 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Gene3D G3DSA:2.130.10.10 341 690 2.1E-86 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 SUPERFAMILY SSF69304 6 258 1.31E-24 T 06-07-2017 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 SUPERFAMILY SSF52096 874 1082 1.26E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 SUPERFAMILY SSF52096 699 778 1.26E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 SMART SM00245 865 1057 1.0E-14 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Pfam PF14684 Tricorn protease C1 domain 702 769 2.9E-27 T 06-07-2017 IPR028204 Tricorn protease C1 domain LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 SUPERFAMILY SSF50156 784 861 9.06E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Pfam PF03572 Peptidase family S41 902 1056 1.9E-23 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 PIRSF PIRSF036421 1 1090 0.0 T 06-07-2017 IPR012393 Tricorn protease GO:0008236 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Gene3D G3DSA:3.30.750.44 699 769 5.8E-31 T 06-07-2017 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Gene3D G3DSA:3.90.226.10 881 1088 6.3E-38 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Gene3D G3DSA:2.120.10.60 3 248 1.6E-54 T 06-07-2017 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Pfam PF14685 Tricorn protease PDZ domain 784 872 1.8E-24 T 06-07-2017 IPR029414 Tricorn protease, PDZ domain LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Gene3D G3DSA:2.30.42.10 782 878 1.5E-30 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Pfam PF07676 WD40-like Beta Propeller Repeat 44 62 0.003 T 06-07-2017 IPR011659 WD40-like Beta Propeller LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Pfam PF07676 WD40-like Beta Propeller Repeat 489 521 4.6E-4 T 06-07-2017 IPR011659 WD40-like Beta Propeller LK06_RS19615 c21b8fa672e283d2b94113a2d8a3b1a9 1109 Pfam PF07676 WD40-like Beta Propeller Repeat 455 466 0.22 T 06-07-2017 IPR011659 WD40-like Beta Propeller LK06_RS29965 6fb50e3ff532db09025d7911b19994f2 349 Gene3D G3DSA:3.40.50.2300 191 323 2.1E-39 T 06-07-2017 LK06_RS29965 6fb50e3ff532db09025d7911b19994f2 349 Pfam PF00356 Bacterial regulatory proteins, lacI family 21 66 5.7E-14 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS29965 6fb50e3ff532db09025d7911b19994f2 349 Pfam PF13377 Periplasmic binding protein-like domain 186 342 6.8E-29 T 06-07-2017 LK06_RS29965 6fb50e3ff532db09025d7911b19994f2 349 Gene3D G3DSA:1.10.260.40 18 69 3.5E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS29965 6fb50e3ff532db09025d7911b19994f2 349 Gene3D G3DSA:3.40.50.2300 70 190 6.6E-39 T 06-07-2017 LK06_RS29965 6fb50e3ff532db09025d7911b19994f2 349 SMART SM00354 19 89 8.0E-24 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS29965 6fb50e3ff532db09025d7911b19994f2 349 ProSitePatterns PS00356 LacI-type HTH domain signature. 22 40 - T 06-07-2017 LK06_RS29965 6fb50e3ff532db09025d7911b19994f2 349 SUPERFAMILY SSF47413 19 77 7.78E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS29965 6fb50e3ff532db09025d7911b19994f2 349 SUPERFAMILY SSF53822 79 342 3.26E-61 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 Gene3D G3DSA:3.40.50.670 466 686 1.9E-75 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 SUPERFAMILY SSF55874 23 241 1.7E-58 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 48 176 4.2E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 636 693 4.6E-25 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 SUPERFAMILY SSF54211 260 452 9.86E-41 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 Gene3D G3DSA:3.30.230.10 259 452 1.2E-51 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 Pfam PF00204 DNA gyrase B 260 452 7.8E-56 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 SUPERFAMILY SSF56719 456 697 7.06E-76 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 Gene3D G3DSA:3.30.565.10 23 241 1.4E-80 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR00418 DNA topoisomerase II family signature 586 598 2.2E-60 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR00418 DNA topoisomerase II family signature 326 339 2.2E-60 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR00418 DNA topoisomerase II family signature 548 564 2.2E-60 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR00418 DNA topoisomerase II family signature 52 67 2.2E-60 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR00418 DNA topoisomerase II family signature 482 496 2.2E-60 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR00418 DNA topoisomerase II family signature 87 100 2.2E-60 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR00418 DNA topoisomerase II family signature 566 583 2.2E-60 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR00418 DNA topoisomerase II family signature 130 144 2.2E-60 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR00418 DNA topoisomerase II family signature 637 653 2.2E-60 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 Pfam PF01751 Toprim domain 481 581 8.0E-16 T 06-07-2017 IPR006171 Toprim domain LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 SMART SM00387 48 208 6.6E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 ProSitePatterns PS00177 DNA topoisomerase II signature. 484 492 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR01159 DNA gyrase subunit B signature 436 456 2.5E-35 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR01159 DNA gyrase subunit B signature 658 670 2.5E-35 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR01159 DNA gyrase subunit B signature 214 229 2.5E-35 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR01159 DNA gyrase subunit B signature 259 281 2.5E-35 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR01159 DNA gyrase subunit B signature 229 242 2.5E-35 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR01159 DNA gyrase subunit B signature 23 33 2.5E-35 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR01159 DNA gyrase subunit B signature 674 690 2.5E-35 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR01159 DNA gyrase subunit B signature 532 541 2.5E-35 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 PRINTS PR01159 DNA gyrase subunit B signature 370 386 2.5E-35 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LK06_RS25295 a6ab82ea8a9d05b116efac94a4aa81ba 707 SMART SM00433 52 698 4.2E-291 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS25775 d159570a68a8ef6410fb43b8749d3da1 105 Pfam PF04358 DsrC like protein 7 105 8.8E-34 T 06-07-2017 IPR007453 Sulphur transfer protein DsrC/TusE LK06_RS25775 d159570a68a8ef6410fb43b8749d3da1 105 Gene3D G3DSA:1.10.10.370 42 105 6.2E-25 T 06-07-2017 LK06_RS25775 d159570a68a8ef6410fb43b8749d3da1 105 PIRSF PIRSF006223 4 105 2.8E-32 T 06-07-2017 IPR007453 Sulphur transfer protein DsrC/TusE LK06_RS25775 d159570a68a8ef6410fb43b8749d3da1 105 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 6 105 6.9E-29 T 06-07-2017 IPR007453 Sulphur transfer protein DsrC/TusE LK06_RS25775 d159570a68a8ef6410fb43b8749d3da1 105 SUPERFAMILY SSF69721 5 105 7.46E-35 T 06-07-2017 IPR025526 DsrC-like domain LK06_RS25775 d159570a68a8ef6410fb43b8749d3da1 105 Gene3D G3DSA:3.30.1420.10 1 40 1.3E-9 T 06-07-2017 LK06_RS26225 9e98f5070f9dedf06a9b037df12e9ef7 376 Gene3D G3DSA:1.10.540.10 20 115 3.4E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS26225 9e98f5070f9dedf06a9b037df12e9ef7 376 PIRSF PIRSF016578 4 376 2.7E-12 T 06-07-2017 LK06_RS26225 9e98f5070f9dedf06a9b037df12e9ef7 376 Gene3D G3DSA:1.20.140.10 223 375 1.8E-20 T 06-07-2017 LK06_RS26225 9e98f5070f9dedf06a9b037df12e9ef7 376 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 222 1.2E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS26225 9e98f5070f9dedf06a9b037df12e9ef7 376 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 248 372 1.2E-10 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS26225 9e98f5070f9dedf06a9b037df12e9ef7 376 SUPERFAMILY SSF56645 20 231 1.44E-47 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS26225 9e98f5070f9dedf06a9b037df12e9ef7 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 25 115 6.6E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS26225 9e98f5070f9dedf06a9b037df12e9ef7 376 Gene3D G3DSA:2.40.110.10 119 222 6.5E-22 T 06-07-2017 LK06_RS26225 9e98f5070f9dedf06a9b037df12e9ef7 376 SUPERFAMILY SSF47203 247 376 9.99E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS03260 3d0038bd782f2f0c30fa05d3ab39b21e 430 Pfam PF08031 Berberine and berberine like 381 426 3.0E-10 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 LK06_RS03260 3d0038bd782f2f0c30fa05d3ab39b21e 430 Gene3D G3DSA:3.30.43.10 2 58 5.8E-11 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS03260 3d0038bd782f2f0c30fa05d3ab39b21e 430 SUPERFAMILY SSF56176 2 176 4.35E-50 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS03260 3d0038bd782f2f0c30fa05d3ab39b21e 430 Pfam PF01565 FAD binding domain 10 144 4.0E-31 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LK06_RS03260 3d0038bd782f2f0c30fa05d3ab39b21e 430 Gene3D G3DSA:3.30.465.10 65 176 4.6E-17 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS19540 9c777322f28a951cd1599dd8ed2b4cba 281 Pfam PF12957 Domain of unknown function (DUF3846) 10 99 2.4E-14 T 06-07-2017 IPR024559 Protein of unknown function DUF3846 LK06_RS19150 4b297e47eff2ab8dd55fd53fa06f5eeb 428 Gene3D G3DSA:1.10.101.10 220 248 8.7E-5 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS19150 4b297e47eff2ab8dd55fd53fa06f5eeb 428 Gene3D G3DSA:1.10.101.10 114 138 8.7E-5 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18905 1af186cb0f8fcfd1fde36309f16816b0 108 Pfam PF00581 Rhodanese-like domain 7 100 3.5E-10 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS18905 1af186cb0f8fcfd1fde36309f16816b0 108 SUPERFAMILY SSF52821 2 107 1.57E-23 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS18905 1af186cb0f8fcfd1fde36309f16816b0 108 SMART SM00450 5 104 9.9E-4 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS18905 1af186cb0f8fcfd1fde36309f16816b0 108 ProSitePatterns PS00380 Rhodanese signature 1. 30 41 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 LK06_RS18905 1af186cb0f8fcfd1fde36309f16816b0 108 Gene3D G3DSA:3.40.250.10 4 107 2.3E-21 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS27375 336359ec5c3c2696c629cfa06fd75707 297 SUPERFAMILY SSF48179 167 295 3.85E-38 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS27375 336359ec5c3c2696c629cfa06fd75707 297 SUPERFAMILY SSF51735 6 166 2.14E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27375 336359ec5c3c2696c629cfa06fd75707 297 PIRSF PIRSF000103 2 296 4.4E-82 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 LK06_RS27375 336359ec5c3c2696c629cfa06fd75707 297 Gene3D G3DSA:1.10.1040.10 169 295 8.0E-42 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS27375 336359ec5c3c2696c629cfa06fd75707 297 Gene3D G3DSA:3.40.50.720 6 167 6.5E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27375 336359ec5c3c2696c629cfa06fd75707 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 166 1.0E-50 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 LK06_RS27375 336359ec5c3c2696c629cfa06fd75707 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 169 288 2.1E-40 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 LK06_RS27375 336359ec5c3c2696c629cfa06fd75707 297 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 7 296 3.7E-149 T 06-07-2017 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 LK06_RS15105 187f8a45f8fbd62d6a6baa8a4be688cc 465 Gene3D G3DSA:3.30.43.10 30 100 8.5E-10 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS15105 187f8a45f8fbd62d6a6baa8a4be688cc 465 SUPERFAMILY SSF56176 16 209 8.88E-54 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS15105 187f8a45f8fbd62d6a6baa8a4be688cc 465 Gene3D G3DSA:3.30.465.10 101 209 3.3E-17 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS15105 187f8a45f8fbd62d6a6baa8a4be688cc 465 SUPERFAMILY SSF55103 189 461 2.75E-7 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LK06_RS15105 187f8a45f8fbd62d6a6baa8a4be688cc 465 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 43 76 - T 06-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 LK06_RS15105 187f8a45f8fbd62d6a6baa8a4be688cc 465 Pfam PF01565 FAD binding domain 43 174 5.1E-29 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LK06_RS15105 187f8a45f8fbd62d6a6baa8a4be688cc 465 Pfam PF08031 Berberine and berberine like 416 461 6.4E-13 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 312 328 1.2E-18 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 285 303 1.2E-18 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 249 262 1.2E-18 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 368 385 1.2E-18 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 296 453 7.7E-43 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 Gene3D G3DSA:3.40.50.720 130 299 2.7E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 Gene3D G3DSA:3.30.360.10 300 455 8.7E-51 T 06-07-2017 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 SMART SM00846 129 291 1.2E-50 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 289 296 - T 06-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 131 465 3.2E-111 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 130 291 2.3E-39 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 SUPERFAMILY SSF55347 291 454 1.1E-48 T 06-07-2017 LK06_RS31150 ca25a43d45cefc93756d9159c1332e93 483 SUPERFAMILY SSF51735 130 307 2.37E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03745 db19a0723ada9bd507024a750e8074ae 1212 Pfam PF01968 Hydantoinase/oxoprolinase 198 485 5.0E-113 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LK06_RS03745 db19a0723ada9bd507024a750e8074ae 1212 Pfam PF02538 Hydantoinase B/oxoprolinase 681 1195 3.3E-198 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LK06_RS03745 db19a0723ada9bd507024a750e8074ae 1212 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 6 178 4.9E-56 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LK06_RS06630 ec24727f768b61efa400b99dff3b1b93 329 Pfam PF02650 WhiA C-terminal HTH domain 221 303 1.4E-19 T 06-07-2017 IPR023054 Sporulation regulator WhiA, C-terminal LK06_RS06630 ec24727f768b61efa400b99dff3b1b93 329 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 7.9E-112 T 06-07-2017 LK06_RS06630 ec24727f768b61efa400b99dff3b1b93 329 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.855 T 06-07-2017 IPR003802 Sporulation regulator WhiA GO:0043937 LK06_RS06630 ec24727f768b61efa400b99dff3b1b93 329 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 5.5E-26 T 06-07-2017 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain LK06_RS06630 ec24727f768b61efa400b99dff3b1b93 329 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 7.3E-24 T 06-07-2017 LK06_RS26570 714145f2251d9a5810164dd4efb51580 509 PIRSF PIRSF006060 5 498 7.5E-94 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS26570 714145f2251d9a5810164dd4efb51580 509 Pfam PF13520 Amino acid permease 29 458 3.8E-54 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS26545 6e142b81b725bf0cbcd285d3d7bcb73d 399 Gene3D G3DSA:1.10.10.10 10 74 8.8E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26545 6e142b81b725bf0cbcd285d3d7bcb73d 399 SUPERFAMILY SSF53067 79 383 4.12E-63 T 06-07-2017 LK06_RS26545 6e142b81b725bf0cbcd285d3d7bcb73d 399 Pfam PF00480 ROK family 82 378 2.0E-62 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS26545 6e142b81b725bf0cbcd285d3d7bcb73d 399 ProSitePatterns PS01125 ROK family signature. 215 242 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS26545 6e142b81b725bf0cbcd285d3d7bcb73d 399 SUPERFAMILY SSF46785 12 70 3.22E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26545 6e142b81b725bf0cbcd285d3d7bcb73d 399 Gene3D G3DSA:3.30.420.40 77 219 1.6E-45 T 06-07-2017 LK06_RS26545 6e142b81b725bf0cbcd285d3d7bcb73d 399 Pfam PF12802 MarR family 17 68 1.2E-8 T 06-07-2017 LK06_RS26545 6e142b81b725bf0cbcd285d3d7bcb73d 399 Gene3D G3DSA:3.30.420.40 220 360 2.2E-50 T 06-07-2017 LK06_RS26280 da2a975d21f77872f0ae29c0d2e3510c 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 2.2E-6 T 06-07-2017 LK06_RS26280 da2a975d21f77872f0ae29c0d2e3510c 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 119 139 2.2E-6 T 06-07-2017 LK06_RS26280 da2a975d21f77872f0ae29c0d2e3510c 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 174 198 2.2E-6 T 06-07-2017 LK06_RS26280 da2a975d21f77872f0ae29c0d2e3510c 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 312 336 2.2E-6 T 06-07-2017 LK06_RS26280 da2a975d21f77872f0ae29c0d2e3510c 487 Pfam PF07690 Major Facilitator Superfamily 29 419 4.2E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS26280 da2a975d21f77872f0ae29c0d2e3510c 487 Gene3D G3DSA:1.20.1250.20 275 478 5.5E-20 T 06-07-2017 LK06_RS26280 da2a975d21f77872f0ae29c0d2e3510c 487 Gene3D G3DSA:1.20.1250.20 27 209 3.2E-30 T 06-07-2017 LK06_RS26280 da2a975d21f77872f0ae29c0d2e3510c 487 SUPERFAMILY SSF103473 258 430 1.09E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS26280 da2a975d21f77872f0ae29c0d2e3510c 487 SUPERFAMILY SSF103473 457 481 1.09E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS26280 da2a975d21f77872f0ae29c0d2e3510c 487 SUPERFAMILY SSF103473 19 211 1.09E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08285 f2b78a56aed5d6e6cff23fac98a70986 214 SUPERFAMILY SSF54506 3 212 1.64E-27 T 06-07-2017 LK06_RS08285 f2b78a56aed5d6e6cff23fac98a70986 214 Gene3D G3DSA:3.10.310.10 129 209 2.1E-7 T 06-07-2017 LK06_RS08285 f2b78a56aed5d6e6cff23fac98a70986 214 Gene3D G3DSA:3.10.310.10 3 118 1.0E-16 T 06-07-2017 LK06_RS08285 f2b78a56aed5d6e6cff23fac98a70986 214 Pfam PF02567 Phenazine biosynthesis-like protein 17 82 5.1E-9 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LK06_RS18645 bd1fb35eb883af11aea5666ecde8fa86 264 Gene3D G3DSA:1.20.120.450 3 150 7.2E-10 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase LK06_RS18645 bd1fb35eb883af11aea5666ecde8fa86 264 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 13 224 9.5E-56 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type LK06_RS18645 bd1fb35eb883af11aea5666ecde8fa86 264 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 6 257 4.9E-113 T 06-07-2017 IPR017518 Conserved hypothetical protein CHP03084 LK06_RS18645 bd1fb35eb883af11aea5666ecde8fa86 264 Pfam PF08608 Wyosine base formation 186 230 4.4E-7 T 06-07-2017 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 LK06_RS18645 bd1fb35eb883af11aea5666ecde8fa86 264 SUPERFAMILY SSF109854 1 153 1.78E-39 T 06-07-2017 LK06_RS18645 bd1fb35eb883af11aea5666ecde8fa86 264 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 147 2.8E-33 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 LK06_RS28460 515bf0a2008a755dd95375a78f8c3b84 228 SUPERFAMILY SSF47413 84 143 1.21E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS28460 515bf0a2008a755dd95375a78f8c3b84 228 Gene3D G3DSA:1.10.260.40 79 152 5.6E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS28460 515bf0a2008a755dd95375a78f8c3b84 228 Pfam PF01381 Helix-turn-helix 88 135 4.8E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS28460 515bf0a2008a755dd95375a78f8c3b84 228 SMART SM00530 75 136 1.9E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS02085 8c889cc51691144fe2db1c3531632ba3 191 SUPERFAMILY SSF88946 2 106 8.11E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS02085 8c889cc51691144fe2db1c3531632ba3 191 SUPERFAMILY SSF88659 106 186 1.36E-9 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS02085 8c889cc51691144fe2db1c3531632ba3 191 Pfam PF04542 Sigma-70 region 2 24 89 2.5E-8 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS02085 8c889cc51691144fe2db1c3531632ba3 191 Gene3D G3DSA:1.10.10.10 122 186 2.0E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02085 8c889cc51691144fe2db1c3531632ba3 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 184 1.7E-18 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS02085 8c889cc51691144fe2db1c3531632ba3 191 Gene3D G3DSA:1.10.1740.10 5 116 2.5E-14 T 06-07-2017 LK06_RS14505 6399c8b4422f5ce49007b9dfcd115632 114 Gene3D G3DSA:3.30.1310.10 5 108 2.4E-40 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family LK06_RS14505 6399c8b4422f5ce49007b9dfcd115632 114 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 8 102 21.737 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family LK06_RS14505 6399c8b4422f5ce49007b9dfcd115632 114 PIRSF PIRSF004555 6 114 1.5E-34 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family LK06_RS14505 6399c8b4422f5ce49007b9dfcd115632 114 Pfam PF02575 YbaB/EbfC DNA-binding family 15 103 5.7E-32 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family LK06_RS14505 6399c8b4422f5ce49007b9dfcd115632 114 SUPERFAMILY SSF82607 14 104 1.31E-27 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family LK06_RS14505 6399c8b4422f5ce49007b9dfcd115632 114 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 6 95 9.7E-25 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 Gene3D G3DSA:3.40.50.720 12 197 5.3E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 Gene3D G3DSA:3.40.50.720 316 503 6.7E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 SUPERFAMILY SSF48179 195 300 3.06E-27 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 Gene3D G3DSA:1.10.1040.10 198 293 4.7E-29 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 Gene3D G3DSA:1.10.1040.10 504 595 8.4E-31 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 15 193 4.8E-59 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 322 499 1.6E-58 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 SUPERFAMILY SSF48179 502 595 6.89E-28 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 SUPERFAMILY SSF51735 12 195 8.34E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 502 596 6.3E-32 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 196 292 2.6E-28 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS28000 30e2fde132b3c68b692d9a541fb6f1a2 601 SUPERFAMILY SSF51735 318 499 1.98E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20295 965616ca93647c8cf9d2f9834b02f2da 284 Gene3D G3DSA:3.40.50.1820 69 275 1.1E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS20295 965616ca93647c8cf9d2f9834b02f2da 284 Pfam PF05057 Putative serine esterase (DUF676) 78 180 1.1E-7 T 06-07-2017 IPR007751 Domain of unknown function DUF676, lipase-like LK06_RS20295 965616ca93647c8cf9d2f9834b02f2da 284 SUPERFAMILY SSF53474 74 215 3.38E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS32275 142e56782ed7b4abd386e0c1128d005a 141 SUPERFAMILY SSF51905 2 139 3.09E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS32275 142e56782ed7b4abd386e0c1128d005a 141 Pfam PF01494 FAD binding domain 2 136 1.9E-26 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS32275 142e56782ed7b4abd386e0c1128d005a 141 Gene3D G3DSA:3.50.50.60 1 136 7.6E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02715 3183ab1fdff47471d950e938217bffb7 224 Gene3D G3DSA:3.40.50.1860 126 198 9.9E-8 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS02715 3183ab1fdff47471d950e938217bffb7 224 SUPERFAMILY SSF53681 141 212 2.22E-7 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS01975 69cd27893a5da204bf7ff91a309b68c3 493 SUPERFAMILY SSF50998 371 478 6.54E-16 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS01975 69cd27893a5da204bf7ff91a309b68c3 493 SUPERFAMILY SSF50998 124 320 6.54E-16 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS01975 69cd27893a5da204bf7ff91a309b68c3 493 Pfam PF13360 PQQ-like domain 212 412 1.4E-15 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat LK06_RS01975 69cd27893a5da204bf7ff91a309b68c3 493 Gene3D G3DSA:2.140.10.10 396 460 1.0E-14 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS01975 69cd27893a5da204bf7ff91a309b68c3 493 Gene3D G3DSA:2.140.10.10 129 360 1.0E-14 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS28650 ee5555a7cbbe8b803c3e00442d8ce001 497 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 162 177 3.8E-11 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS28650 ee5555a7cbbe8b803c3e00442d8ce001 497 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 209 224 3.8E-11 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS28650 ee5555a7cbbe8b803c3e00442d8ce001 497 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 334 346 3.8E-11 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS28650 ee5555a7cbbe8b803c3e00442d8ce001 497 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 330 3.8E-11 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS28650 ee5555a7cbbe8b803c3e00442d8ce001 497 Pfam PF01433 Peptidase family M1 49 368 1.1E-44 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS28650 ee5555a7cbbe8b803c3e00442d8ce001 497 SUPERFAMILY SSF63737 33 225 3.4E-37 T 06-07-2017 LK06_RS28650 ee5555a7cbbe8b803c3e00442d8ce001 497 SUPERFAMILY SSF55486 235 462 1.47E-52 T 06-07-2017 LK06_RS28650 ee5555a7cbbe8b803c3e00442d8ce001 497 Gene3D G3DSA:1.10.390.10 329 462 1.5E-22 T 06-07-2017 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 SMART SM00382 99 303 4.0E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 Gene3D G3DSA:1.20.120.140 2 89 2.5E-35 T 06-07-2017 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 431 6.3E-173 T 06-07-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 Pfam PF02978 Signal peptide binding domain 333 430 2.5E-30 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 SMART SM00963 1 86 2.3E-34 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.9E-21 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 449 33.06 T 06-07-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 SMART SM00962 100 298 3.4E-109 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 Gene3D G3DSA:3.40.50.300 94 299 1.5E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 271 284 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 SUPERFAMILY SSF52540 42 359 5.24E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 SUPERFAMILY SSF47446 332 433 3.92E-33 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 Pfam PF00448 SRP54-type protein, GTPase domain 100 297 3.1E-70 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24390 720b8403572677f9bb909225623ed4e4 516 Gene3D G3DSA:1.10.260.30 333 434 8.6E-37 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 LK06_RS27005 074910dd435ed27e85249f7d087f28ab 135 Gene3D G3DSA:3.10.180.10 4 131 7.9E-29 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS27005 074910dd435ed27e85249f7d087f28ab 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 124 2.7E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS27005 074910dd435ed27e85249f7d087f28ab 135 SUPERFAMILY SSF54593 5 129 8.99E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS31450 d9e97387fc106f160694794c3a3cf850 227 SUPERFAMILY SSF48498 78 208 2.43E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS31450 d9e97387fc106f160694794c3a3cf850 227 Gene3D G3DSA:1.10.357.10 3 182 5.6E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS31450 d9e97387fc106f160694794c3a3cf850 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.7E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS31450 d9e97387fc106f160694794c3a3cf850 227 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS31450 d9e97387fc106f160694794c3a3cf850 227 SUPERFAMILY SSF46689 4 63 4.82E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS31450 d9e97387fc106f160694794c3a3cf850 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 5.9E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS31450 d9e97387fc106f160694794c3a3cf850 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 5.9E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS02705 9fe7e10cb1cf4fa60fcb5a4e3ba2d375 345 SUPERFAMILY SSF54593 2 334 1.43E-64 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS02705 9fe7e10cb1cf4fa60fcb5a4e3ba2d375 345 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 1 344 3.7E-100 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 LK06_RS02705 9fe7e10cb1cf4fa60fcb5a4e3ba2d375 345 Gene3D G3DSA:3.10.180.10 1 129 1.8E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS02705 9fe7e10cb1cf4fa60fcb5a4e3ba2d375 345 Gene3D G3DSA:3.10.180.10 150 344 6.3E-54 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS02705 9fe7e10cb1cf4fa60fcb5a4e3ba2d375 345 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 4 129 2.9E-11 T 06-07-2017 LK06_RS02705 9fe7e10cb1cf4fa60fcb5a4e3ba2d375 345 PIRSF PIRSF009283 1 345 1.8E-101 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 LK06_RS02705 9fe7e10cb1cf4fa60fcb5a4e3ba2d375 345 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 154 300 3.0E-13 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS18785 8b22e57b9c52a9a10631adef0f24b91d 402 Pfam PF04909 Amidohydrolase 86 394 1.3E-48 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS18785 8b22e57b9c52a9a10631adef0f24b91d 402 SUPERFAMILY SSF51556 7 36 7.56E-77 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS18785 8b22e57b9c52a9a10631adef0f24b91d 402 SUPERFAMILY SSF51556 86 396 7.56E-77 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS18785 8b22e57b9c52a9a10631adef0f24b91d 402 Gene3D G3DSA:3.20.20.140 83 395 4.2E-71 T 06-07-2017 LK06_RS18785 8b22e57b9c52a9a10631adef0f24b91d 402 Gene3D G3DSA:3.20.20.140 8 35 4.2E-71 T 06-07-2017 LK06_RS28590 68bab1b47e7ea759324de7d06410e0b8 98 Pfam PF03795 YCII-related domain 1 81 5.2E-15 T 06-07-2017 IPR005545 YCII-related LK06_RS28590 68bab1b47e7ea759324de7d06410e0b8 98 SUPERFAMILY SSF54909 1 83 3.22E-18 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS28590 68bab1b47e7ea759324de7d06410e0b8 98 Gene3D G3DSA:3.30.70.1060 12 82 8.5E-10 T 06-07-2017 LK06_RS23785 50e2707331052e7f55a982fcb616172b 365 Pfam PF00005 ABC transporter 45 207 4.4E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS23785 50e2707331052e7f55a982fcb616172b 365 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 258 348 2.7E-24 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS23785 50e2707331052e7f55a982fcb616172b 365 SUPERFAMILY SSF52540 25 278 1.77E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23785 50e2707331052e7f55a982fcb616172b 365 Gene3D G3DSA:3.40.50.300 24 280 4.5E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23785 50e2707331052e7f55a982fcb616172b 365 ProSitePatterns PS00211 ABC transporters family signature. 180 194 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS23785 50e2707331052e7f55a982fcb616172b 365 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 259 320 5.3E-20 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS23785 50e2707331052e7f55a982fcb616172b 365 SMART SM00382 53 257 4.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS15450 170b55efb874adec96ad1ceb781dff70 387 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 36 363 3.3E-130 T 06-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LK06_RS15450 170b55efb874adec96ad1ceb781dff70 387 Gene3D G3DSA:3.40.50.970 37 363 7.2E-120 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS15450 170b55efb874adec96ad1ceb781dff70 387 SUPERFAMILY SSF52518 34 372 3.22E-96 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS15450 170b55efb874adec96ad1ceb781dff70 387 Pfam PF00676 Dehydrogenase E1 component 65 343 1.8E-73 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 LK06_RS13715 733890e276001f8d913053f325d79412 392 Pfam PF01212 Beta-eliminating lyase 68 294 1.2E-25 T 06-07-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 LK06_RS13715 733890e276001f8d913053f325d79412 392 Gene3D G3DSA:3.40.640.10 64 263 1.4E-34 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS13715 733890e276001f8d913053f325d79412 392 SUPERFAMILY SSF53383 64 327 2.2E-57 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 SUPERFAMILY SSF48264 24 478 1.3E-104 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 Pfam PF00067 Cytochrome P450 27 457 3.0E-80 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 Gene3D G3DSA:1.10.630.10 25 479 6.2E-113 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 PRINTS PR00385 P450 superfamily signature 427 438 1.0E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 PRINTS PR00385 P450 superfamily signature 341 352 1.0E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 PRINTS PR00385 P450 superfamily signature 288 305 1.0E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 PRINTS PR00385 P450 superfamily signature 418 427 1.0E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 420 429 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 PRINTS PR00463 E-class P450 group I signature 417 427 4.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 PRINTS PR00463 E-class P450 group I signature 55 74 4.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 PRINTS PR00463 E-class P450 group I signature 277 294 4.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 PRINTS PR00463 E-class P450 group I signature 297 323 4.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01265 15e7e8da6c3dcca638766152de37ee7c 531 PRINTS PR00463 E-class P450 group I signature 427 450 4.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS25080 f9627c4ff99323838dba1b76b5dcdaca 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 223 7.4E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS25080 f9627c4ff99323838dba1b76b5dcdaca 228 Pfam PF00072 Response regulator receiver domain 4 113 1.8E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25080 f9627c4ff99323838dba1b76b5dcdaca 228 Gene3D G3DSA:3.40.50.2300 1 125 2.3E-36 T 06-07-2017 LK06_RS25080 f9627c4ff99323838dba1b76b5dcdaca 228 SMART SM00862 151 223 1.4E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS25080 f9627c4ff99323838dba1b76b5dcdaca 228 Gene3D G3DSA:1.10.10.10 128 226 7.2E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25080 f9627c4ff99323838dba1b76b5dcdaca 228 SMART SM00448 1 113 1.6E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25080 f9627c4ff99323838dba1b76b5dcdaca 228 SUPERFAMILY SSF52172 1 185 1.37E-37 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS29230 589b85e0a2eecaed7da4baa6d9c85daa 404 Gene3D G3DSA:1.20.1250.20 3 177 2.6E-15 T 06-07-2017 LK06_RS29230 589b85e0a2eecaed7da4baa6d9c85daa 404 Gene3D G3DSA:1.20.1250.20 202 380 1.3E-17 T 06-07-2017 LK06_RS29230 589b85e0a2eecaed7da4baa6d9c85daa 404 Pfam PF07690 Major Facilitator Superfamily 18 341 3.2E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS29230 589b85e0a2eecaed7da4baa6d9c85daa 404 SUPERFAMILY SSF103473 3 379 3.92E-39 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 Gene3D G3DSA:3.30.1360.40 101 176 9.9E-29 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 SUPERFAMILY SSF55252 110 175 8.89E-19 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 120 155 2.0E-13 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 Gene3D G3DSA:1.10.10.10 17 90 2.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 Pfam PF02863 Arginine repressor, C-terminal domain 109 173 7.2E-24 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 Pfam PF01316 Arginine repressor, DNA binding domain 20 87 4.0E-24 T 06-07-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 PRINTS PR01467 Bacterial arginine repressor signature 55 70 5.7E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 PRINTS PR01467 Bacterial arginine repressor signature 116 129 5.7E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 PRINTS PR01467 Bacterial arginine repressor signature 146 161 5.7E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 PRINTS PR01467 Bacterial arginine repressor signature 39 52 5.7E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 SUPERFAMILY SSF46785 19 88 7.41E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 Hamap MF_00173 Arginine repressor [argR]. 1 180 56.476 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 LK06_RS04690 49313ed82d4c50e4c923513a77585e56 181 TIGRFAM TIGR01529 argR_whole: arginine repressor 23 176 4.6E-44 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 51 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 SUPERFAMILY SSF52374 23 360 5.14E-48 T 06-07-2017 LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 SUPERFAMILY SSF48163 366 578 6.93E-22 T 06-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 Gene3D G3DSA:3.40.50.620 309 362 2.2E-4 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 Gene3D G3DSA:2.30.30.300 219 253 2.0E-9 T 06-07-2017 IPR023386 Lysine-tRNA ligase, insertion domain GO:0004824 KEGG: 00970+6.1.1.6 LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 Gene3D G3DSA:1.10.10.350 484 577 2.7E-17 T 06-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 11 579 31.163 T 06-07-2017 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 Pfam PF01921 tRNA synthetases class I (K) 12 386 1.7E-130 T 06-07-2017 LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 Gene3D G3DSA:3.40.50.620 20 173 2.7E-56 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 Gene3D G3DSA:3.40.50.620 262 308 2.7E-56 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 Gene3D G3DSA:3.40.50.620 211 218 2.7E-56 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS13350 088d79b7bc344c6330f4ea120c207ba3 579 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 212 575 1.2E-49 T 06-07-2017 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 Gene3D G3DSA:3.40.50.300 620 817 1.7E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 Gene3D G3DSA:3.30.2060.10 149 224 9.7E-15 T 06-07-2017 LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 Pfam PF03461 TRCF domain 1044 1126 1.9E-24 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 SMART SM01058 506 607 8.2E-48 T 06-07-2017 IPR003711 CarD-like/TRCF domain LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 SUPERFAMILY SSF52540 813 1021 4.58E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 SMART SM00982 1043 1141 1.1E-36 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 SUPERFAMILY SSF52540 556 814 5.6E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1136 28.595 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 SUPERFAMILY SSF52540 390 489 1.27E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 Pfam PF00270 DEAD/DEAH box helicase 638 798 9.4E-17 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 167 1116 0.0 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 Pfam PF02559 CarD-like/TRCF domain 507 606 1.4E-31 T 06-07-2017 IPR003711 CarD-like/TRCF domain LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 SUPERFAMILY SSF141259 500 579 2.09E-18 T 06-07-2017 IPR003711 CarD-like/TRCF domain LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 Gene3D G3DSA:3.40.50.300 834 987 2.8E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 SMART SM00487 631 821 3.8E-30 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 SUPERFAMILY SSF52540 19 367 9.74E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 SMART SM00490 857 941 3.6E-15 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 SUPERFAMILY SSF143517 1033 1151 1.01E-31 T 06-07-2017 LK06_RS19880 e20610b04bee04ef66e09dd4bc8ee5e1 1188 Pfam PF00271 Helicase conserved C-terminal domain 841 940 2.4E-14 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 9.0E-6 T 06-07-2017 LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 PRINTS PR00145 Argininosuccinate lyase family signature 173 193 9.0E-6 T 06-07-2017 LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 Hamap MF_00743 Fumarate hydratase class II [fumC]. 8 465 81.643 T 06-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 Gene3D G3DSA:1.20.200.10 137 415 6.9E-98 T 06-07-2017 LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 Pfam PF10415 Fumarase C C-terminus 406 464 1.9E-21 T 06-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 4.1E-35 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 4.1E-35 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 4.1E-35 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 4.1E-35 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 Gene3D G3DSA:1.10.40.30 416 465 2.7E-22 T 06-07-2017 LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 SUPERFAMILY SSF48557 8 464 4.4E-146 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 Pfam PF00206 Lyase 16 340 9.0E-104 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal LK06_RS21435 78110c9275358b065f895de99e1ee8ab 465 Gene3D G3DSA:1.10.275.10 7 136 2.2E-51 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal LK06_RS12320 d35654293dc2e94d70aeab4558b9f5eb 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 06-07-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12320 d35654293dc2e94d70aeab4558b9f5eb 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.897 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12320 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.6E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12320 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.6E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12320 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.6E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12320 d35654293dc2e94d70aeab4558b9f5eb 102 SUPERFAMILY SSF54999 5 102 1.02E-38 T 06-07-2017 IPR027486 Ribosomal protein S10 domain LK06_RS12320 d35654293dc2e94d70aeab4558b9f5eb 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 7.9E-37 T 06-07-2017 IPR027486 Ribosomal protein S10 domain LK06_RS12320 d35654293dc2e94d70aeab4558b9f5eb 102 SMART SM01403 7 101 3.5E-59 T 06-07-2017 IPR027486 Ribosomal protein S10 domain LK06_RS12320 d35654293dc2e94d70aeab4558b9f5eb 102 Gene3D G3DSA:3.30.70.600 4 102 5.6E-45 T 06-07-2017 IPR027486 Ribosomal protein S10 domain LK06_RS12320 d35654293dc2e94d70aeab4558b9f5eb 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.1E-47 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS29260 20d70c2d2becbb7eb60dfbab4f87abb9 265 SUPERFAMILY SSF109854 14 149 2.04E-9 T 06-07-2017 LK06_RS29260 20d70c2d2becbb7eb60dfbab4f87abb9 265 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 22 239 1.4E-31 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type LK06_RS29260 20d70c2d2becbb7eb60dfbab4f87abb9 265 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 21 143 2.6E-21 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 LK06_RS29260 20d70c2d2becbb7eb60dfbab4f87abb9 265 Pfam PF07398 MDMPI C-terminal domain 157 257 1.9E-18 T 06-07-2017 IPR010872 MDMPI C-terminal LK06_RS30410 d4d496f26a7217a1c23ab81d9fd6840d 239 Gene3D G3DSA:2.40.30.10 12 109 6.8E-26 T 06-07-2017 LK06_RS30410 d4d496f26a7217a1c23ab81d9fd6840d 239 SUPERFAMILY SSF63380 12 116 3.25E-29 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS30410 d4d496f26a7217a1c23ab81d9fd6840d 239 Gene3D G3DSA:3.40.50.80 116 239 1.9E-17 T 06-07-2017 LK06_RS30410 d4d496f26a7217a1c23ab81d9fd6840d 239 SUPERFAMILY SSF52343 113 238 3.67E-23 T 06-07-2017 LK06_RS30410 d4d496f26a7217a1c23ab81d9fd6840d 239 PRINTS PR00409 Phthalate dioxygenase reductase family signature 63 77 8.6E-7 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 LK06_RS30410 d4d496f26a7217a1c23ab81d9fd6840d 239 PRINTS PR00409 Phthalate dioxygenase reductase family signature 122 141 8.6E-7 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 LK06_RS30410 d4d496f26a7217a1c23ab81d9fd6840d 239 PRINTS PR00409 Phthalate dioxygenase reductase family signature 100 114 8.6E-7 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 LK06_RS30410 d4d496f26a7217a1c23ab81d9fd6840d 239 PRINTS PR00409 Phthalate dioxygenase reductase family signature 206 214 8.6E-7 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 LK06_RS30410 d4d496f26a7217a1c23ab81d9fd6840d 239 Pfam PF00970 Oxidoreductase FAD-binding domain 18 112 1.4E-14 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 LK06_RS27395 f6bcee304c66b320935334aa696be837 170 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 13 166 3.3E-57 T 06-07-2017 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 LK06_RS27395 f6bcee304c66b320935334aa696be837 170 Gene3D G3DSA:1.10.3330.10 16 168 3.2E-42 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 LK06_RS27395 f6bcee304c66b320935334aa696be837 170 Pfam PF09349 OHCU decarboxylase 14 163 4.8E-36 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 LK06_RS27395 f6bcee304c66b320935334aa696be837 170 SUPERFAMILY SSF158694 9 166 7.19E-40 T 06-07-2017 LK06_RS10440 6f6b5b20b67af119d1b5e31b27d5e4c4 500 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 LK06_RS10440 6f6b5b20b67af119d1b5e31b27d5e4c4 500 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 482 1.5E-257 T 06-07-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 LK06_RS10440 6f6b5b20b67af119d1b5e31b27d5e4c4 500 Pfam PF00171 Aldehyde dehydrogenase family 22 478 4.8E-138 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS10440 6f6b5b20b67af119d1b5e31b27d5e4c4 500 Gene3D G3DSA:3.40.605.10 5 261 3.5E-89 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS10440 6f6b5b20b67af119d1b5e31b27d5e4c4 500 Gene3D G3DSA:3.40.309.10 262 443 1.4E-63 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS10440 6f6b5b20b67af119d1b5e31b27d5e4c4 500 SUPERFAMILY SSF53720 2 484 1.31E-146 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS15955 fcf4fe18a03463721d99133911c65f69 360 SUPERFAMILY SSF51735 3 185 4.03E-93 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15955 fcf4fe18a03463721d99133911c65f69 360 SUPERFAMILY SSF51735 297 356 4.03E-93 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15955 fcf4fe18a03463721d99133911c65f69 360 Gene3D G3DSA:3.40.50.720 1 189 2.0E-116 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15955 fcf4fe18a03463721d99133911c65f69 360 Gene3D G3DSA:3.40.50.720 301 355 2.0E-116 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15955 fcf4fe18a03463721d99133911c65f69 360 Gene3D G3DSA:3.30.360.10 190 300 5.3E-48 T 06-07-2017 LK06_RS15955 fcf4fe18a03463721d99133911c65f69 360 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 300 4.4E-32 T 06-07-2017 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 LK06_RS15955 fcf4fe18a03463721d99133911c65f69 360 PIRSF PIRSF015578 1 359 5.9E-93 T 06-07-2017 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 LK06_RS15955 fcf4fe18a03463721d99133911c65f69 360 SUPERFAMILY SSF55347 190 299 1.14E-34 T 06-07-2017 LK06_RS15955 fcf4fe18a03463721d99133911c65f69 360 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 4 354 2.2E-223 T 06-07-2017 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria LK06_RS03980 4eb7465c12a8978cea64dc722c0eb267 570 Gene3D G3DSA:3.40.50.720 48 80 9.5E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03980 4eb7465c12a8978cea64dc722c0eb267 570 Pfam PF01593 Flavin containing amine oxidoreductase 59 539 2.2E-45 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 LK06_RS03980 4eb7465c12a8978cea64dc722c0eb267 570 SUPERFAMILY SSF54373 363 483 4.71E-27 T 06-07-2017 LK06_RS03980 4eb7465c12a8978cea64dc722c0eb267 570 Gene3D G3DSA:3.50.50.60 508 548 5.5E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS03980 4eb7465c12a8978cea64dc722c0eb267 570 Gene3D G3DSA:3.50.50.60 304 363 5.5E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS03980 4eb7465c12a8978cea64dc722c0eb267 570 SUPERFAMILY SSF51905 505 545 6.85E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS03980 4eb7465c12a8978cea64dc722c0eb267 570 SUPERFAMILY SSF51905 49 382 6.85E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS03980 4eb7465c12a8978cea64dc722c0eb267 570 Gene3D G3DSA:3.90.660.10 367 474 7.1E-27 T 06-07-2017 LK06_RS03980 4eb7465c12a8978cea64dc722c0eb267 570 Gene3D G3DSA:3.90.660.10 81 154 7.1E-27 T 06-07-2017 LK06_RS16010 2dbf0ae0fb3a7529fd11b9bc52dd1bea 445 PIRSF PIRSF006603 10 445 3.0E-61 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LK06_RS16010 2dbf0ae0fb3a7529fd11b9bc52dd1bea 445 Pfam PF01554 MatE 25 183 1.5E-29 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LK06_RS16010 2dbf0ae0fb3a7529fd11b9bc52dd1bea 445 Pfam PF01554 MatE 243 396 3.8E-22 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LK06_RS16010 2dbf0ae0fb3a7529fd11b9bc52dd1bea 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 415 6.1E-105 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LK06_RS22720 dfd7e1295420328115217789d6a21b29 212 SUPERFAMILY SSF52540 35 208 2.39E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22720 dfd7e1295420328115217789d6a21b29 212 Pfam PF03029 Conserved hypothetical ATP binding protein 40 208 2.8E-25 T 06-07-2017 IPR004130 GPN-loop GTPase LK06_RS22720 dfd7e1295420328115217789d6a21b29 212 Gene3D G3DSA:3.40.50.300 36 203 3.9E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06750 e88a1dc83fe4a00f8be1edd73988670a 210 Gene3D G3DSA:3.40.50.300 15 199 5.4E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06750 e88a1dc83fe4a00f8be1edd73988670a 210 SUPERFAMILY SSF52540 46 180 9.03E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26000 1cce310eb0a15fe71a51be186f56a9f6 129 Pfam PF04472 Protein of unknown function (DUF552) 47 117 1.2E-18 T 06-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 LK06_RS10310 fd6c91ea524e07491a8e8ae0488f0c74 194 SMART SM00756 8 149 7.4E-53 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 LK06_RS10310 fd6c91ea524e07491a8e8ae0488f0c74 194 Pfam PF07884 Vitamin K epoxide reductase family 14 145 2.5E-28 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 LK06_RS03470 71280c056908158c3fc5b03f5826379b 191 Pfam PF13401 AAA domain 91 186 1.2E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS03470 71280c056908158c3fc5b03f5826379b 191 SUPERFAMILY SSF52540 88 162 4.13E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03470 71280c056908158c3fc5b03f5826379b 191 Gene3D G3DSA:3.40.50.300 85 159 6.9E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07135 6788c3b30e7655bc4daf56baab727897 241 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 4 239 4.9E-118 T 06-07-2017 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 LK06_RS07135 6788c3b30e7655bc4daf56baab727897 241 Pfam PF00977 Histidine biosynthesis protein 6 231 3.1E-62 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 LK06_RS07135 6788c3b30e7655bc4daf56baab727897 241 Gene3D G3DSA:3.20.20.70 5 238 1.5E-71 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS07135 6788c3b30e7655bc4daf56baab727897 241 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 238 31.938 T 06-07-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 LK06_RS07135 6788c3b30e7655bc4daf56baab727897 241 SUPERFAMILY SSF51366 4 237 2.59E-63 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 LK06_RS04820 6bfa1b7da4b7f4dc6e2e3a29762e2d56 212 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 170 2.6E-61 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 LK06_RS04820 6bfa1b7da4b7f4dc6e2e3a29762e2d56 212 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 84 167 5.9E-34 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 LK06_RS04820 6bfa1b7da4b7f4dc6e2e3a29762e2d56 212 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 170 29.674 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 LK06_RS04820 6bfa1b7da4b7f4dc6e2e3a29762e2d56 212 Gene3D G3DSA:3.10.20.80 3 78 5.6E-35 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 LK06_RS04820 6bfa1b7da4b7f4dc6e2e3a29762e2d56 212 SUPERFAMILY SSF54364 5 78 3.01E-28 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 LK06_RS04820 6bfa1b7da4b7f4dc6e2e3a29762e2d56 212 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 7 76 6.9E-29 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 LK06_RS04820 6bfa1b7da4b7f4dc6e2e3a29762e2d56 212 Gene3D G3DSA:3.30.110.10 79 171 1.8E-38 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 LK06_RS04820 6bfa1b7da4b7f4dc6e2e3a29762e2d56 212 SUPERFAMILY SSF55200 85 169 3.92E-32 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 123 1.3E-21 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 SUPERFAMILY SSF51621 245 533 1.31E-84 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 SUPERFAMILY SSF52009 123 238 1.29E-30 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 Gene3D G3DSA:3.20.20.60 250 551 5.0E-87 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 Gene3D G3DSA:1.10.274.10 28 129 4.6E-21 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 PIRSF PIRSF000732 1 556 5.7E-170 T 06-07-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 SUPERFAMILY SSF47831 29 140 6.67E-21 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 524 4.6E-78 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 Gene3D G3DSA:3.50.30.10 130 244 5.5E-34 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 431 449 - T 06-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 431 446 9.5E-17 T 06-07-2017 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 9.5E-17 T 06-07-2017 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 484 496 9.5E-17 T 06-07-2017 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 9.5E-17 T 06-07-2017 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 Pfam PF00391 PEP-utilising enzyme, mobile domain 151 221 3.6E-22 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 181 192 - T 06-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 LK06_RS03695 4749a92d4634cbaa149dcec482957a9b 556 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 546 3.6E-125 T 06-07-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 68 171 2.5E-18 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 SUPERFAMILY SSF48179 189 280 4.08E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 302 393 6.5E-14 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 6 391 4.5E-87 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 SMART SM00984 301 396 3.8E-16 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 Gene3D G3DSA:3.40.50.720 6 183 1.8E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 PIRSF PIRSF500136 1 402 2.1E-119 T 06-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 SUPERFAMILY SSF51735 6 183 3.4E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 Gene3D G3DSA:3.40.50.720 220 394 1.2E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 189 256 1.2E-18 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 SUPERFAMILY SSF52413 288 395 1.14E-19 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS20175 24b898c501031fc682c17063290bcb7a 402 PIRSF PIRSF000124 56 401 3.0E-37 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LK06_RS22135 57e64b6438d77bf0365a14a5eae60cc6 213 SUPERFAMILY SSF48498 92 204 2.45E-29 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS22135 57e64b6438d77bf0365a14a5eae60cc6 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.6E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS22135 57e64b6438d77bf0365a14a5eae60cc6 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.6E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS22135 57e64b6438d77bf0365a14a5eae60cc6 213 Gene3D G3DSA:1.10.357.10 11 203 3.2E-44 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS22135 57e64b6438d77bf0365a14a5eae60cc6 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 5.5E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS22135 57e64b6438d77bf0365a14a5eae60cc6 213 SUPERFAMILY SSF46689 12 94 1.05E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 Gene3D G3DSA:3.20.20.80 259 623 5.8E-92 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 Pfam PF00128 Alpha amylase, catalytic domain 282 351 2.8E-10 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 113 732 43.068 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 137 219 2.1E-19 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 SUPERFAMILY SSF51011 635 732 2.3E-24 T 06-07-2017 LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 PIRSF PIRSF000463 23 733 1.5E-294 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 Gene3D G3DSA:2.60.40.1180 635 731 1.6E-24 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 SMART SM00642 262 621 2.8E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 121 729 1.3E-291 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 SUPERFAMILY SSF81296 32 125 1.9E-21 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 SUPERFAMILY SSF51445 192 629 1.54E-109 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 640 731 7.6E-17 T 06-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 Gene3D G3DSA:2.60.40.10 126 233 1.5E-36 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS30960 bea159c1ec32b89f97f48073626f57da 733 Gene3D G3DSA:2.60.40.10 32 118 1.1E-17 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 Gene3D G3DSA:1.10.287.130 233 303 5.4E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 Gene3D G3DSA:3.30.565.10 312 457 1.1E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 SMART SM00388 243 309 2.9E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 SMART SM00387 352 457 4.2E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 SUPERFAMILY SSF47384 226 307 2.35E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 9.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 401 9.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 456 9.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 415 9.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 SMART SM00304 188 242 8.1E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 SUPERFAMILY SSF158472 189 239 1.7E-6 T 06-07-2017 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 SUPERFAMILY SSF55874 312 456 3.8E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 308 1.6E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 Pfam PF00672 HAMP domain 169 239 3.5E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS19090 65399ffab030615b929ea2eedb46f120 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 456 9.0E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13380 b7f5168c356a8da70efe6e0017431b1e 128 SUPERFAMILY SSF54593 15 125 7.12E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS13380 b7f5168c356a8da70efe6e0017431b1e 128 Gene3D G3DSA:3.10.180.10 14 126 1.2E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS01700 9811a8d7a566eaf119d781143854cfa9 1007 SUPERFAMILY SSF88688 518 622 3.27E-26 T 06-07-2017 IPR028995 Glycoside hydrolase families 57/38, central domain LK06_RS01700 9811a8d7a566eaf119d781143854cfa9 1007 Gene3D G3DSA:1.20.1270.50 522 619 8.6E-23 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 LK06_RS01700 9811a8d7a566eaf119d781143854cfa9 1007 SUPERFAMILY SSF74650 617 1005 1.98E-61 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 LK06_RS01700 9811a8d7a566eaf119d781143854cfa9 1007 Gene3D G3DSA:3.20.110.10 203 521 4.2E-84 T 06-07-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain LK06_RS01700 9811a8d7a566eaf119d781143854cfa9 1007 SUPERFAMILY SSF88713 249 517 3.38E-75 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS01700 9811a8d7a566eaf119d781143854cfa9 1007 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 255 510 2.9E-83 T 06-07-2017 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 LK06_RS01700 9811a8d7a566eaf119d781143854cfa9 1007 SMART SM00872 519 597 6.0E-37 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 LK06_RS01700 9811a8d7a566eaf119d781143854cfa9 1007 Pfam PF09261 Alpha mannosidase middle domain 519 596 5.5E-26 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 LK06_RS01700 9811a8d7a566eaf119d781143854cfa9 1007 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 660 1003 1.3E-61 T 06-07-2017 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 LK06_RS19690 8eebca5ac47f65743defd2c7d8797971 282 PIRSF PIRSF005917 1 280 2.6E-88 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS19690 8eebca5ac47f65743defd2c7d8797971 282 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 224 32.988 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS19690 8eebca5ac47f65743defd2c7d8797971 282 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 207 9.1E-31 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS19690 8eebca5ac47f65743defd2c7d8797971 282 Gene3D G3DSA:3.40.1010.10 3 113 2.2E-6 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS19690 8eebca5ac47f65743defd2c7d8797971 282 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 271 2.1E-61 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS19690 8eebca5ac47f65743defd2c7d8797971 282 SUPERFAMILY SSF53790 3 222 4.58E-73 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS19690 8eebca5ac47f65743defd2c7d8797971 282 Gene3D G3DSA:3.30.950.10 114 225 3.8E-44 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS03440 cbe1010730477df88771568cc487f48b 528 Pfam PF01609 Transposase DDE domain 272 367 1.1E-7 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS03440 cbe1010730477df88771568cc487f48b 528 Pfam PF05598 Transposase domain (DUF772) 53 127 3.2E-17 T 06-07-2017 IPR008490 Transposase InsH, N-terminal LK06_RS03440 cbe1010730477df88771568cc487f48b 528 Pfam PF13751 Transposase DDE domain 393 510 1.7E-22 T 06-07-2017 IPR025668 Transposase DDE domain LK06_RS25300 cbe1010730477df88771568cc487f48b 528 Pfam PF01609 Transposase DDE domain 272 367 1.1E-7 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS25300 cbe1010730477df88771568cc487f48b 528 Pfam PF05598 Transposase domain (DUF772) 53 127 3.2E-17 T 06-07-2017 IPR008490 Transposase InsH, N-terminal LK06_RS25300 cbe1010730477df88771568cc487f48b 528 Pfam PF13751 Transposase DDE domain 393 510 1.7E-22 T 06-07-2017 IPR025668 Transposase DDE domain LK06_RS13730 cbe1010730477df88771568cc487f48b 528 Pfam PF01609 Transposase DDE domain 272 367 1.1E-7 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS13730 cbe1010730477df88771568cc487f48b 528 Pfam PF05598 Transposase domain (DUF772) 53 127 3.2E-17 T 06-07-2017 IPR008490 Transposase InsH, N-terminal LK06_RS13730 cbe1010730477df88771568cc487f48b 528 Pfam PF13751 Transposase DDE domain 393 510 1.7E-22 T 06-07-2017 IPR025668 Transposase DDE domain LK06_RS13415 cb2b9a20b0f3781a3c8b424283a9e64a 569 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 19 33 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 LK06_RS13415 cb2b9a20b0f3781a3c8b424283a9e64a 569 Gene3D G3DSA:3.30.950.10 151 291 1.9E-30 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS13415 cb2b9a20b0f3781a3c8b424283a9e64a 569 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 242 2.4E-34 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS13415 cb2b9a20b0f3781a3c8b424283a9e64a 569 SUPERFAMILY SSF53790 11 290 2.36E-44 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS13415 cb2b9a20b0f3781a3c8b424283a9e64a 569 Pfam PF02602 Uroporphyrinogen-III synthase HemD 301 530 1.6E-64 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13415 cb2b9a20b0f3781a3c8b424283a9e64a 569 SUPERFAMILY SSF69618 287 537 1.14E-66 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LK06_RS13415 cb2b9a20b0f3781a3c8b424283a9e64a 569 Gene3D G3DSA:3.40.1010.10 13 149 5.0E-30 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS13415 cb2b9a20b0f3781a3c8b424283a9e64a 569 Gene3D G3DSA:3.40.50.10090 292 414 5.0E-41 T 06-07-2017 LK06_RS13415 cb2b9a20b0f3781a3c8b424283a9e64a 569 Gene3D G3DSA:3.40.50.10090 422 542 9.3E-35 T 06-07-2017 LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 PRINTS PR00096 Glutamine amidotransferase superfamily signature 488 497 1.7E-10 T 06-07-2017 LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 PRINTS PR00096 Glutamine amidotransferase superfamily signature 607 620 1.7E-10 T 06-07-2017 LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 PRINTS PR00096 Glutamine amidotransferase superfamily signature 522 533 1.7E-10 T 06-07-2017 LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 Gene3D G3DSA:3.60.120.10 88 381 1.3E-55 T 06-07-2017 IPR005801 ADC synthase GO:0009058 LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 Gene3D G3DSA:3.40.50.880 443 632 8.1E-30 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 Pfam PF00117 Glutamine amidotransferase class-I 445 625 3.3E-23 T 06-07-2017 IPR017926 Glutamine amidotransferase LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 Pfam PF00425 chorismate binding enzyme 107 371 2.3E-41 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 SUPERFAMILY SSF52317 444 632 7.2E-23 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 SUPERFAMILY SSF56322 57 380 1.02E-60 T 06-07-2017 IPR005801 ADC synthase GO:0009058 LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 PRINTS PR00097 Anthranilate synthase component II signature 607 620 1.4E-9 T 06-07-2017 LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 PRINTS PR00097 Anthranilate synthase component II signature 522 533 1.4E-9 T 06-07-2017 LK06_RS07475 2b33a8d9c908cc494798890a7ae92ec1 644 PRINTS PR00097 Anthranilate synthase component II signature 443 457 1.4E-9 T 06-07-2017 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 10 21 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 SUPERFAMILY SSF53067 9 203 1.17E-63 T 06-07-2017 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 Gene3D G3DSA:3.30.420.40 8 211 9.4E-13 T 06-07-2017 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 210 227 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 TIGRFAM TIGR00016 ackA: acetate kinase 8 401 6.9E-143 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 PRINTS PR00471 Acetate kinase family signature 180 193 2.1E-44 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 PRINTS PR00471 Acetate kinase family signature 210 231 2.1E-44 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 PRINTS PR00471 Acetate kinase family signature 306 319 2.1E-44 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 PRINTS PR00471 Acetate kinase family signature 328 344 2.1E-44 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 PRINTS PR00471 Acetate kinase family signature 10 21 2.1E-44 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 PRINTS PR00471 Acetate kinase family signature 383 395 2.1E-44 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 Gene3D G3DSA:3.30.420.40 212 401 5.2E-77 T 06-07-2017 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 Hamap MF_00020 Acetate kinase [ackA]. 1 405 175.087 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 PIRSF PIRSF000722 6 406 1.1E-144 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 SUPERFAMILY SSF53067 165 402 2.09E-83 T 06-07-2017 LK06_RS23545 e48b7a2d83f2bdaa85f86f37fe93e776 406 Pfam PF00871 Acetokinase family 10 395 1.8E-148 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LK06_RS09785 74bf37813894bddc0155abf543fa60c8 2314 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1837 1917 3.9E-19 T 06-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 LK06_RS09785 74bf37813894bddc0155abf543fa60c8 2314 SMART SM00306 2066 2168 0.0051 T 06-07-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 LK06_RS09785 74bf37813894bddc0155abf543fa60c8 2314 Gene3D G3DSA:2.170.16.10 2068 2247 2.0E-21 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain LK06_RS09785 74bf37813894bddc0155abf543fa60c8 2314 SUPERFAMILY SSF51294 2068 2211 1.57E-16 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain LK06_RS09785 74bf37813894bddc0155abf543fa60c8 2314 Pfam PF07591 Pretoxin HINT domain 2083 2211 2.4E-16 T 06-07-2017 LK06_RS01195 25ab9c3e025dba0c0bc02d8e92797814 318 Gene3D G3DSA:1.10.10.60 266 315 2.1E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01195 25ab9c3e025dba0c0bc02d8e92797814 318 Gene3D G3DSA:1.10.10.60 222 265 2.7E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01195 25ab9c3e025dba0c0bc02d8e92797814 318 SMART SM00342 228 311 1.7E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS01195 25ab9c3e025dba0c0bc02d8e92797814 318 SUPERFAMILY SSF46689 265 316 7.43E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01195 25ab9c3e025dba0c0bc02d8e92797814 318 Pfam PF12833 Helix-turn-helix domain 234 312 7.7E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS01195 25ab9c3e025dba0c0bc02d8e92797814 318 SUPERFAMILY SSF46689 217 262 1.61E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01195 25ab9c3e025dba0c0bc02d8e92797814 318 SUPERFAMILY SSF52317 7 194 2.02E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS01195 25ab9c3e025dba0c0bc02d8e92797814 318 Gene3D G3DSA:3.40.50.880 9 221 2.5E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS01195 25ab9c3e025dba0c0bc02d8e92797814 318 Pfam PF01965 DJ-1/PfpI family 9 173 4.9E-16 T 06-07-2017 IPR002818 DJ-1/PfpI LK06_RS17500 fe382d29b947b31a74b32026b0c2e344 329 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 27 321 2.7E-90 T 06-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 LK06_RS17500 fe382d29b947b31a74b32026b0c2e344 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 319 4.4E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS17500 fe382d29b947b31a74b32026b0c2e344 329 SUPERFAMILY SSF161098 49 313 1.44E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS17500 fe382d29b947b31a74b32026b0c2e344 329 Gene3D G3DSA:1.10.3720.10 38 324 2.7E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS20065 0bfed211420130f62277d52bbc4a809f 170 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 21 142 3.3E-27 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 LK06_RS20065 0bfed211420130f62277d52bbc4a809f 170 Gene3D G3DSA:3.40.50.300 13 162 1.2E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20065 0bfed211420130f62277d52bbc4a809f 170 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 18 139 2.4E-30 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 LK06_RS20065 0bfed211420130f62277d52bbc4a809f 170 SUPERFAMILY SSF52540 34 144 1.32E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12090 a76b2273c0d2a700257a8ddb867d9f74 554 SUPERFAMILY SSF111326 4 549 2.09E-246 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LK06_RS12090 a76b2273c0d2a700257a8ddb867d9f74 554 Gene3D G3DSA:3.40.50.10730 137 343 6.7E-83 T 06-07-2017 LK06_RS12090 a76b2273c0d2a700257a8ddb867d9f74 554 Hamap MF_00577 Urocanate hydratase [hutU]. 2 550 48.783 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LK06_RS12090 a76b2273c0d2a700257a8ddb867d9f74 554 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 1.1E-271 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LK06_RS12090 a76b2273c0d2a700257a8ddb867d9f74 554 Gene3D G3DSA:3.40.1770.10 354 548 1.4E-151 T 06-07-2017 LK06_RS12090 a76b2273c0d2a700257a8ddb867d9f74 554 Gene3D G3DSA:3.40.1770.10 6 136 1.4E-151 T 06-07-2017 LK06_RS12090 a76b2273c0d2a700257a8ddb867d9f74 554 PIRSF PIRSF001423 1 554 2.1E-278 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LK06_RS12090 a76b2273c0d2a700257a8ddb867d9f74 554 Pfam PF01175 Urocanase 7 541 1.8E-251 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LK06_RS12090 a76b2273c0d2a700257a8ddb867d9f74 554 ProSitePatterns PS01233 Urocanase signature. 436 451 - T 06-07-2017 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LK06_RS04435 98709eca33ebb8e827d6971e7d04a322 600 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 208 325 2.1E-6 T 06-07-2017 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 LK06_RS04435 98709eca33ebb8e827d6971e7d04a322 600 SUPERFAMILY SSF52540 188 551 4.21E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04435 98709eca33ebb8e827d6971e7d04a322 600 Gene3D G3DSA:3.40.50.300 204 292 5.8E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04435 98709eca33ebb8e827d6971e7d04a322 600 Gene3D G3DSA:3.40.50.300 409 558 5.8E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13665 37e8e74e4cee2c349fb82b83e65323bd 111 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 110 5.0E-39 T 06-07-2017 IPR024412 Lsr2 LK06_RS13665 37e8e74e4cee2c349fb82b83e65323bd 111 Pfam PF11774 Lsr2 2 109 2.7E-40 T 06-07-2017 IPR024412 Lsr2 LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 Gene3D G3DSA:1.10.101.10 29 92 9.7E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 Gene3D G3DSA:1.10.101.10 98 137 1.6E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 Gene3D G3DSA:1.10.101.10 216 255 1.9E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 Gene3D G3DSA:1.10.101.10 149 211 2.2E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 Gene3D G3DSA:3.90.1720.10 280 378 2.7E-7 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 Pfam PF05257 CHAP domain 312 393 8.2E-11 T 06-07-2017 IPR007921 CHAP domain LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 SUPERFAMILY SSF54001 276 378 8.09E-7 T 06-07-2017 LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 SUPERFAMILY SSF47090 149 206 6.28E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 SUPERFAMILY SSF47090 98 138 1.31E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 SUPERFAMILY SSF47090 217 256 3.66E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 SUPERFAMILY SSF47090 28 87 3.4E-14 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 Pfam PF01471 Putative peptidoglycan binding domain 150 205 1.5E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 Pfam PF01471 Putative peptidoglycan binding domain 100 136 2.8E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 Pfam PF01471 Putative peptidoglycan binding domain 219 255 2.0E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18390 6ebe38a8dc8c061a04c573e1451bbe1b 419 Pfam PF01471 Putative peptidoglycan binding domain 31 86 1.5E-16 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS27665 fb0db190eac52b129872dcc6ec1e7bfd 323 Pfam PF00483 Nucleotidyl transferase 31 266 2.0E-22 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LK06_RS27665 fb0db190eac52b129872dcc6ec1e7bfd 323 SUPERFAMILY SSF53448 30 312 1.17E-60 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS27665 fb0db190eac52b129872dcc6ec1e7bfd 323 Gene3D G3DSA:3.90.550.10 30 303 3.2E-67 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 Gene3D G3DSA:1.10.630.10 15 407 1.8E-114 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 SUPERFAMILY SSF48264 14 407 2.88E-91 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00385 P450 superfamily signature 346 355 9.6E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00385 P450 superfamily signature 242 259 9.6E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00385 P450 superfamily signature 277 288 9.6E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00385 P450 superfamily signature 355 366 9.6E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00359 B-class P450 signature 355 366 2.1E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00359 B-class P450 signature 142 158 2.1E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00359 B-class P450 signature 295 322 2.1E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00359 B-class P450 signature 95 106 2.1E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00359 B-class P450 signature 346 355 2.1E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00359 B-class P450 signature 277 288 2.1E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 PRINTS PR00359 B-class P450 signature 196 218 2.1E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 Pfam PF00067 Cytochrome P450 277 377 8.5E-16 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS00700 3972264e5b9a74cfd8a6efb63d48ea94 408 Pfam PF00067 Cytochrome P450 208 263 3.5E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS03130 53ad2db3a081c11bdd42b53db5fb5e32 227 SMART SM00986 52 211 1.3E-34 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS03130 53ad2db3a081c11bdd42b53db5fb5e32 227 SMART SM00987 52 211 1.3E-34 T 06-07-2017 LK06_RS03130 53ad2db3a081c11bdd42b53db5fb5e32 227 Gene3D G3DSA:3.40.470.10 5 223 5.2E-95 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS03130 53ad2db3a081c11bdd42b53db5fb5e32 227 Pfam PF03167 Uracil DNA glycosylase superfamily 56 208 9.5E-23 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS03130 53ad2db3a081c11bdd42b53db5fb5e32 227 SUPERFAMILY SSF52141 6 223 5.89E-89 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS03130 53ad2db3a081c11bdd42b53db5fb5e32 227 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 8 222 40.787 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS03130 53ad2db3a081c11bdd42b53db5fb5e32 227 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 9 214 6.9E-80 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS03130 53ad2db3a081c11bdd42b53db5fb5e32 227 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 60 69 - T 06-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS07920 f4da5d77ffd596b838c9be0e5e775f9e 368 Gene3D G3DSA:3.30.70.1090 156 242 9.5E-4 T 06-07-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 LK06_RS07920 f4da5d77ffd596b838c9be0e5e775f9e 368 Pfam PF04486 SchA/CurD like domain 148 259 6.3E-49 T 06-07-2017 IPR007575 SchA/CurD-like domain LK06_RS07920 f4da5d77ffd596b838c9be0e5e775f9e 368 SUPERFAMILY SSF54909 31 121 5.01E-19 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS07920 f4da5d77ffd596b838c9be0e5e775f9e 368 Gene3D G3DSA:3.30.70.900 35 120 3.7E-14 T 06-07-2017 LK06_RS07920 f4da5d77ffd596b838c9be0e5e775f9e 368 Pfam PF03992 Antibiotic biosynthesis monooxygenase 32 104 2.8E-14 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain LK06_RS04895 ef63aeb042d872bafffe707da0cc317d 242 SUPERFAMILY SSF53807 2 237 1.3E-30 T 06-07-2017 LK06_RS04895 ef63aeb042d872bafffe707da0cc317d 242 Gene3D G3DSA:3.40.50.1980 130 210 1.6E-10 T 06-07-2017 LK06_RS04895 ef63aeb042d872bafffe707da0cc317d 242 Gene3D G3DSA:3.40.50.1980 2 106 5.6E-19 T 06-07-2017 LK06_RS25125 60112e0bc3787ef4b702c1b390e7e255 312 Pfam PF01715 IPP transferase 43 285 4.2E-73 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 LK06_RS25125 60112e0bc3787ef4b702c1b390e7e255 312 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 10 307 26.987 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 LK06_RS25125 60112e0bc3787ef4b702c1b390e7e255 312 SUPERFAMILY SSF52540 11 152 1.1E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25125 60112e0bc3787ef4b702c1b390e7e255 312 Gene3D G3DSA:3.40.50.300 8 176 6.6E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25125 60112e0bc3787ef4b702c1b390e7e255 312 Gene3D G3DSA:1.10.287.890 201 282 3.8E-26 T 06-07-2017 LK06_RS25125 60112e0bc3787ef4b702c1b390e7e255 312 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 289 2.0E-73 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 LK06_RS31570 e598abd889c287a6c1092b40b3f141b8 201 Gene3D G3DSA:2.80.10.50 71 199 7.7E-9 T 06-07-2017 LK06_RS31570 e598abd889c287a6c1092b40b3f141b8 201 SUPERFAMILY SSF50370 75 199 6.86E-14 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS03610 6271a53246a6676cfa18d579518f00b1 961 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 20 953 0.0 T 06-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 LK06_RS03610 6271a53246a6676cfa18d579518f00b1 961 SUPERFAMILY SSF53383 932 955 3.48E-99 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS03610 6271a53246a6676cfa18d579518f00b1 961 SUPERFAMILY SSF53383 480 890 3.48E-99 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS03610 6271a53246a6676cfa18d579518f00b1 961 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 11 959 25.633 T 06-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 LK06_RS03610 6271a53246a6676cfa18d579518f00b1 961 Pfam PF02347 Glycine cleavage system P-protein 453 736 4.9E-12 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 LK06_RS03610 6271a53246a6676cfa18d579518f00b1 961 Pfam PF02347 Glycine cleavage system P-protein 19 447 6.9E-178 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 LK06_RS03610 6271a53246a6676cfa18d579518f00b1 961 Gene3D G3DSA:3.40.640.10 505 741 8.2E-40 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS03610 6271a53246a6676cfa18d579518f00b1 961 Gene3D G3DSA:3.40.640.10 94 309 1.5E-17 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS03610 6271a53246a6676cfa18d579518f00b1 961 SUPERFAMILY SSF53383 20 438 2.34E-102 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS25605 8e3afc92555b7ca7a7388227096d45a1 334 SUPERFAMILY SSF52540 65 197 3.75E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25605 8e3afc92555b7ca7a7388227096d45a1 334 SUPERFAMILY SSF52540 224 321 3.75E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25605 8e3afc92555b7ca7a7388227096d45a1 334 SMART SM00382 76 259 1.7E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS25605 8e3afc92555b7ca7a7388227096d45a1 334 Pfam PF07728 AAA domain (dynein-related subfamily) 80 240 8.0E-9 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 LK06_RS25605 8e3afc92555b7ca7a7388227096d45a1 334 Gene3D G3DSA:3.40.50.300 60 275 5.7E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14020 83b3f807842616318b238668ca5f00db 113 SUPERFAMILY SSF52091 3 110 4.32E-31 T 06-07-2017 IPR002645 STAS domain LK06_RS14020 83b3f807842616318b238668ca5f00db 113 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 107 4.9E-33 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 LK06_RS14020 83b3f807842616318b238668ca5f00db 113 Pfam PF01740 STAS domain 12 108 1.9E-17 T 06-07-2017 IPR002645 STAS domain LK06_RS14020 83b3f807842616318b238668ca5f00db 113 Gene3D G3DSA:3.30.750.24 4 111 2.9E-40 T 06-07-2017 IPR002645 STAS domain LK06_RS05765 29723dfa84d2fe50a590dca89451d4ec 271 Gene3D G3DSA:3.40.50.150 99 184 5.4E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS05765 29723dfa84d2fe50a590dca89451d4ec 271 Pfam PF01479 S4 domain 7 49 3.2E-11 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS05765 29723dfa84d2fe50a590dca89451d4ec 271 PIRSF PIRSF005578 3 268 1.9E-93 T 06-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 LK06_RS05765 29723dfa84d2fe50a590dca89451d4ec 271 SMART SM00363 7 74 2.5E-7 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS05765 29723dfa84d2fe50a590dca89451d4ec 271 Pfam PF01728 FtsJ-like methyltransferase 65 250 7.0E-18 T 06-07-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 LK06_RS05765 29723dfa84d2fe50a590dca89451d4ec 271 Gene3D G3DSA:3.10.290.10 7 98 7.0E-25 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS05765 29723dfa84d2fe50a590dca89451d4ec 271 SUPERFAMILY SSF53335 56 251 2.16E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS05765 29723dfa84d2fe50a590dca89451d4ec 271 SUPERFAMILY SSF55174 5 87 2.5E-12 T 06-07-2017 LK06_RS05765 29723dfa84d2fe50a590dca89451d4ec 271 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 8 245 1.1E-59 T 06-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 LK06_RS07810 f42338f5ec5946ba19fd7926671eb089 903 Gene3D G3DSA:3.40.50.970 487 724 2.4E-110 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS07810 f42338f5ec5946ba19fd7926671eb089 903 SUPERFAMILY SSF52518 488 720 1.02E-87 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS07810 f42338f5ec5946ba19fd7926671eb089 903 SUPERFAMILY SSF52922 728 903 9.94E-49 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS07810 f42338f5ec5946ba19fd7926671eb089 903 Gene3D G3DSA:3.40.50.920 729 903 5.2E-66 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS07810 f42338f5ec5946ba19fd7926671eb089 903 PIRSF PIRSF000156 5 903 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LK06_RS07810 f42338f5ec5946ba19fd7926671eb089 903 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 15 902 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LK06_RS07810 f42338f5ec5946ba19fd7926671eb089 903 Gene3D G3DSA:3.40.50.970 66 481 2.7E-134 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS07810 f42338f5ec5946ba19fd7926671eb089 903 SUPERFAMILY SSF52518 66 480 9.74E-113 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS07810 f42338f5ec5946ba19fd7926671eb089 903 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 150 302 9.1E-10 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS16265 b8a21ece4e351b92b01d2ab92aad6b75 256 Pfam PF07987 Domain of unkown function (DUF1775) 41 189 1.7E-49 T 06-07-2017 IPR012533 GLE1, N-terminal, bacteria LK06_RS00140 f99c25d8f1c24fb1afc4ac0816972f5f 242 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 121 239 4.2E-24 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related LK06_RS00140 f99c25d8f1c24fb1afc4ac0816972f5f 242 SUPERFAMILY SSF50475 115 240 1.15E-21 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS00140 f99c25d8f1c24fb1afc4ac0816972f5f 242 Pfam PF13560 Helix-turn-helix domain 35 95 3.6E-7 T 06-07-2017 LK06_RS00140 f99c25d8f1c24fb1afc4ac0816972f5f 242 Gene3D G3DSA:2.30.110.10 110 241 1.3E-40 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS00140 f99c25d8f1c24fb1afc4ac0816972f5f 242 SMART SM00530 39 95 2.1E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS00140 f99c25d8f1c24fb1afc4ac0816972f5f 242 SUPERFAMILY SSF47413 30 97 8.0E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS00140 f99c25d8f1c24fb1afc4ac0816972f5f 242 Gene3D G3DSA:1.10.260.40 36 105 2.3E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS26675 d40b782c6ef346d113a9a443071a1df3 293 SUPERFAMILY SSF53098 120 287 7.44E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS26675 d40b782c6ef346d113a9a443071a1df3 293 Gene3D G3DSA:3.30.420.10 121 280 1.7E-28 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS26675 d40b782c6ef346d113a9a443071a1df3 293 Pfam PF00665 Integrase core domain 126 240 3.6E-25 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 LK06_RS26675 d40b782c6ef346d113a9a443071a1df3 293 Pfam PF13276 HTH-like domain 45 102 6.9E-18 T 06-07-2017 IPR025948 HTH-like domain LK06_RS25685 e7642d9b1e60c3ddb9a04ab1776d4463 654 SUPERFAMILY SSF52540 349 647 1.69E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25685 e7642d9b1e60c3ddb9a04ab1776d4463 654 SUPERFAMILY SSF52540 137 214 1.69E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25685 e7642d9b1e60c3ddb9a04ab1776d4463 654 Gene3D G3DSA:3.40.50.300 430 518 6.1E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25685 e7642d9b1e60c3ddb9a04ab1776d4463 654 Gene3D G3DSA:3.40.50.300 302 332 6.1E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25685 e7642d9b1e60c3ddb9a04ab1776d4463 654 Gene3D G3DSA:3.40.50.300 137 216 6.1E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25685 e7642d9b1e60c3ddb9a04ab1776d4463 654 Gene3D G3DSA:3.40.50.300 519 650 7.7E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25685 e7642d9b1e60c3ddb9a04ab1776d4463 654 Pfam PF13245 Part of AAA domain 152 214 1.4E-16 T 06-07-2017 LK06_RS25685 e7642d9b1e60c3ddb9a04ab1776d4463 654 Pfam PF01443 Viral (Superfamily 1) RNA helicase 448 647 6.5E-8 T 06-07-2017 IPR027351 (+) RNA virus helicase core domain GO:0005524 LK06_RS30815 1c9cafd15f6922853f35260ff5e45ce6 273 Pfam PF00264 Common central domain of tyrosinase 30 229 2.5E-43 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS30815 1c9cafd15f6922853f35260ff5e45ce6 273 Gene3D G3DSA:1.10.1280.10 1 272 3.9E-63 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre LK06_RS30815 1c9cafd15f6922853f35260ff5e45ce6 273 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 209 220 - T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS30815 1c9cafd15f6922853f35260ff5e45ce6 273 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 54 71 - T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS30815 1c9cafd15f6922853f35260ff5e45ce6 273 SUPERFAMILY SSF48056 1 272 6.28E-66 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre LK06_RS30815 1c9cafd15f6922853f35260ff5e45ce6 273 PRINTS PR00092 Tyrosinase copper-binding domain signature 189 200 4.3E-20 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS30815 1c9cafd15f6922853f35260ff5e45ce6 273 PRINTS PR00092 Tyrosinase copper-binding domain signature 54 71 4.3E-20 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS30815 1c9cafd15f6922853f35260ff5e45ce6 273 PRINTS PR00092 Tyrosinase copper-binding domain signature 83 88 4.3E-20 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS30815 1c9cafd15f6922853f35260ff5e45ce6 273 PRINTS PR00092 Tyrosinase copper-binding domain signature 208 226 4.3E-20 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 SUPERFAMILY SSF55785 148 262 8.84E-28 T 06-07-2017 IPR000014 PAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 SUPERFAMILY SSF55785 12 130 1.15E-18 T 06-07-2017 IPR000014 PAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 18 136 3.2E-17 T 06-07-2017 IPR000014 PAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 135 260 1.9E-25 T 06-07-2017 IPR000014 PAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 Gene3D G3DSA:3.30.750.24 273 365 3.0E-12 T 06-07-2017 IPR002645 STAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 Pfam PF13426 PAS domain 147 252 1.1E-13 T 06-07-2017 IPR000014 PAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 Pfam PF13426 PAS domain 30 131 7.8E-13 T 06-07-2017 IPR000014 PAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 Pfam PF01740 STAS domain 275 365 9.0E-7 T 06-07-2017 IPR002645 STAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 SUPERFAMILY SSF52091 272 382 5.49E-17 T 06-07-2017 IPR002645 STAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 SMART SM00091 16 85 0.02 T 06-07-2017 IPR000014 PAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 SMART SM00091 137 203 3.7E-7 T 06-07-2017 IPR000014 PAS domain LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 Gene3D G3DSA:3.30.450.20 14 130 4.2E-20 T 06-07-2017 LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 Gene3D G3DSA:3.30.450.20 135 251 2.4E-22 T 06-07-2017 LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 SMART SM00086 90 132 0.04 T 06-07-2017 IPR001610 PAC motif LK06_RS11470 c4cd622eecf7c56d2357db8c9b7e2a6d 407 SMART SM00086 213 253 0.33 T 06-07-2017 IPR001610 PAC motif LK06_RS30150 e292289ab8ebb0798212b06cb2313815 159 Gene3D G3DSA:3.90.79.10 9 136 6.6E-31 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS30150 e292289ab8ebb0798212b06cb2313815 159 Pfam PF00293 NUDIX domain 22 132 1.4E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS30150 e292289ab8ebb0798212b06cb2313815 159 SUPERFAMILY SSF55811 12 141 5.42E-32 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS22825 a3dfc8ee6da338aa877829b76432b50a 385 SUPERFAMILY SSF52172 258 377 1.71E-10 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS22825 a3dfc8ee6da338aa877829b76432b50a 385 Pfam PF00072 Response regulator receiver domain 260 362 1.8E-6 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS22825 a3dfc8ee6da338aa877829b76432b50a 385 Gene3D G3DSA:3.40.50.2300 259 364 9.9E-12 T 06-07-2017 LK06_RS18165 68ad7921c8b40261755390c2be43d1db 468 SUPERFAMILY SSF51905 184 310 9.5E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS18165 68ad7921c8b40261755390c2be43d1db 468 SUPERFAMILY SSF51905 14 105 9.5E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS18165 68ad7921c8b40261755390c2be43d1db 468 Pfam PF01266 FAD dependent oxidoreductase 36 395 5.1E-49 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS18165 68ad7921c8b40261755390c2be43d1db 468 Gene3D G3DSA:3.30.9.10 255 353 9.2E-7 T 06-07-2017 LK06_RS18165 68ad7921c8b40261755390c2be43d1db 468 Gene3D G3DSA:3.30.9.10 132 182 9.2E-7 T 06-07-2017 LK06_RS18165 68ad7921c8b40261755390c2be43d1db 468 Gene3D G3DSA:3.50.50.60 357 401 3.5E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS18165 68ad7921c8b40261755390c2be43d1db 468 Gene3D G3DSA:3.50.50.60 26 116 3.5E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS18165 68ad7921c8b40261755390c2be43d1db 468 Gene3D G3DSA:3.50.50.60 183 254 3.5E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 Pfam PF02983 Alpha-lytic protease prodomain 39 88 5.2E-9 T 06-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 PIRSF PIRSF001134 6 283 3.0E-83 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 233 244 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 224 247 3.9E-39 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 248 262 3.9E-39 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 183 203 3.9E-39 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 204 221 3.9E-39 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 131 145 3.9E-39 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 Gene3D G3DSA:2.40.10.10 107 186 8.9E-27 T 06-07-2017 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 SUPERFAMILY SSF50494 111 276 2.0E-36 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 Gene3D G3DSA:3.30.300.50 42 98 2.0E-8 T 06-07-2017 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 Gene3D G3DSA:2.40.10.10 187 270 5.3E-29 T 06-07-2017 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 Pfam PF00089 Trypsin 132 275 2.1E-9 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 LK06_RS05575 b7374d79f539ee64fead2b81d8245e0a 283 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 133 138 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 LK06_RS27255 d18bc68bc8aaf7e0551578987bae402b 420 Pfam PF13535 ATP-grasp domain 150 297 4.3E-8 T 06-07-2017 LK06_RS27255 d18bc68bc8aaf7e0551578987bae402b 420 SUPERFAMILY SSF56059 90 324 2.65E-35 T 06-07-2017 LK06_RS27255 d18bc68bc8aaf7e0551578987bae402b 420 Gene3D G3DSA:3.30.470.20 109 324 6.7E-23 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 SUPERFAMILY SSF54980 416 493 2.37E-25 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Gene3D G3DSA:3.30.230.10 496 610 1.8E-47 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Gene3D G3DSA:3.30.70.870 417 492 6.0E-38 T 06-07-2017 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 706 0.0 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 SMART SM00889 492 612 3.2E-70 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Pfam PF03144 Elongation factor Tu domain 2 336 403 3.2E-15 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Pfam PF00679 Elongation factor G C-terminus 614 700 1.2E-29 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 SUPERFAMILY SSF54980 617 704 1.58E-29 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Gene3D G3DSA:3.40.50.300 7 298 2.1E-105 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 184 3.7E-33 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.2E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.2E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.2E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.2E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 PRINTS PR00315 GTP-binding elongation factor signature 59 67 4.2E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Pfam PF14492 Elongation Factor G, domain II 416 490 5.4E-34 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Gene3D G3DSA:3.30.70.240 611 705 2.7E-34 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Pfam PF03764 Elongation factor G, domain IV 491 612 6.1E-48 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Pfam PF00009 Elongation factor Tu GTP binding domain 10 293 2.4E-66 T 06-07-2017 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Gene3D G3DSA:2.40.30.10 317 416 6.3E-39 T 06-07-2017 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 SMART SM00838 614 701 4.6E-57 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 SUPERFAMILY SSF52540 7 293 3.06E-104 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 Hamap MF_00054_B Elongation factor G [fusA]. 7 705 110.245 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 SUPERFAMILY SSF50447 276 416 1.79E-36 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS12405 9da363cbe54ff5a1351bf50d7b90e8e3 708 SUPERFAMILY SSF54211 491 613 4.05E-41 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS26020 5e329896b4ae3d3affee4fdbd0355f7d 398 SUPERFAMILY SSF52540 279 331 2.04E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26020 5e329896b4ae3d3affee4fdbd0355f7d 398 SUPERFAMILY SSF52540 34 157 2.04E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26020 5e329896b4ae3d3affee4fdbd0355f7d 398 Gene3D G3DSA:3.40.1140.10 33 121 4.4E-10 T 06-07-2017 LK06_RS26020 5e329896b4ae3d3affee4fdbd0355f7d 398 Gene3D G3DSA:3.40.1140.10 304 367 4.4E-10 T 06-07-2017 LK06_RS22290 57c2a6624186e9aeae9475962795f316 371 SUPERFAMILY SSF51735 23 328 1.84E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22290 57c2a6624186e9aeae9475962795f316 371 Gene3D G3DSA:3.40.50.720 22 234 8.6E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22290 57c2a6624186e9aeae9475962795f316 371 Pfam PF01370 NAD dependent epimerase/dehydratase family 27 235 8.1E-16 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS07610 3c4dae86e2d58b84477cfb59d53bea94 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 19 351 35.688 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 LK06_RS07610 3c4dae86e2d58b84477cfb59d53bea94 354 Gene3D G3DSA:3.40.1030.10 86 352 5.7E-104 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS07610 3c4dae86e2d58b84477cfb59d53bea94 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 20 80 2.0E-19 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS07610 3c4dae86e2d58b84477cfb59d53bea94 354 SUPERFAMILY SSF52418 87 352 9.16E-85 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS07610 3c4dae86e2d58b84477cfb59d53bea94 354 Pfam PF00591 Glycosyl transferase family, a/b domain 88 341 1.3E-82 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS07610 3c4dae86e2d58b84477cfb59d53bea94 354 Gene3D G3DSA:1.20.970.10 16 80 5.9E-26 T 06-07-2017 LK06_RS07610 3c4dae86e2d58b84477cfb59d53bea94 354 SUPERFAMILY SSF47648 17 83 7.2E-21 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 LK06_RS07610 3c4dae86e2d58b84477cfb59d53bea94 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 22 350 2.3E-110 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 LK06_RS26455 af1acde270dcd5336ff2fd39eb1f8ed7 180 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 13 180 2.4E-17 T 06-07-2017 LK06_RS26455 af1acde270dcd5336ff2fd39eb1f8ed7 180 SUPERFAMILY SSF49899 3 180 1.21E-22 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain LK06_RS26455 af1acde270dcd5336ff2fd39eb1f8ed7 180 Gene3D G3DSA:2.60.120.200 4 180 7.2E-17 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain LK06_RS27345 576358918abb470d100b280b61d5951a 535 Gene3D G3DSA:2.30.38.10 355 429 5.8E-29 T 06-07-2017 LK06_RS27345 576358918abb470d100b280b61d5951a 535 Pfam PF00501 AMP-binding enzyme 26 438 6.0E-115 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS27345 576358918abb470d100b280b61d5951a 535 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS27345 576358918abb470d100b280b61d5951a 535 SUPERFAMILY SSF56801 19 534 5.76E-163 T 06-07-2017 LK06_RS27345 576358918abb470d100b280b61d5951a 535 Gene3D G3DSA:3.40.50.980 202 347 1.3E-52 T 06-07-2017 LK06_RS27345 576358918abb470d100b280b61d5951a 535 Pfam PF13193 AMP-binding enzyme C-terminal domain 447 523 1.7E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS27345 576358918abb470d100b280b61d5951a 535 Gene3D G3DSA:3.30.300.30 433 533 1.2E-32 T 06-07-2017 LK06_RS27345 576358918abb470d100b280b61d5951a 535 Gene3D G3DSA:3.40.50.980 20 201 3.0E-40 T 06-07-2017 LK06_RS19260 a02543792e4e795ed7b0f2d66a9b36f5 270 SUPERFAMILY SSF48498 146 253 1.22E-29 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS19260 a02543792e4e795ed7b0f2d66a9b36f5 270 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 81 94 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS19260 a02543792e4e795ed7b0f2d66a9b36f5 270 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 101 124 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS19260 a02543792e4e795ed7b0f2d66a9b36f5 270 Gene3D G3DSA:1.10.357.10 70 258 7.1E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS19260 a02543792e4e795ed7b0f2d66a9b36f5 270 Pfam PF00440 Bacterial regulatory proteins, tetR family 81 126 4.1E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS19260 a02543792e4e795ed7b0f2d66a9b36f5 270 SUPERFAMILY SSF46689 69 150 1.35E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS26535 ddf86988dfcd4f22c6c7fe544499e69f 311 SUPERFAMILY SSF161098 51 298 8.24E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26535 ddf86988dfcd4f22c6c7fe544499e69f 311 Gene3D G3DSA:1.10.3720.10 57 307 4.3E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26535 ddf86988dfcd4f22c6c7fe544499e69f 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 301 2.7E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS22165 779a210f85c8a38ef955d61e3d70879c 319 SUPERFAMILY SSF51735 284 312 8.82E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22165 779a210f85c8a38ef955d61e3d70879c 319 SUPERFAMILY SSF51735 1 257 8.82E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22165 779a210f85c8a38ef955d61e3d70879c 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 2.9E-31 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS22165 779a210f85c8a38ef955d61e3d70879c 319 Gene3D G3DSA:3.40.50.720 1 160 3.6E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22165 779a210f85c8a38ef955d61e3d70879c 319 Gene3D G3DSA:3.40.50.720 202 241 3.6E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22165 779a210f85c8a38ef955d61e3d70879c 319 Gene3D G3DSA:3.90.25.10 282 311 1.7E-5 T 06-07-2017 LK06_RS22165 779a210f85c8a38ef955d61e3d70879c 319 Gene3D G3DSA:3.90.25.10 185 201 1.7E-5 T 06-07-2017 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 301 1.6E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 Gene3D G3DSA:3.50.50.60 113 313 6.5E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 SUPERFAMILY SSF51905 12 286 7.66E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 Pfam PF14759 Reductase C-terminal 324 406 5.9E-27 T 06-07-2017 IPR028202 Reductase, C-terminal LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 Gene3D G3DSA:3.50.50.60 14 112 2.5E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 5.4E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 5.4E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 15 37 5.4E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 Gene3D G3DSA:3.30.390.30 324 406 5.8E-30 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 SUPERFAMILY SSF55424 317 407 4.67E-29 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.2E-24 T 06-07-2017 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.2E-24 T 06-07-2017 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.2E-24 T 06-07-2017 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 1.2E-24 T 06-07-2017 LK06_RS07420 d8b00d8b25efe39d1c7804d5d70b9c0b 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 1.2E-24 T 06-07-2017 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 Gene3D G3DSA:1.10.601.10 86 240 3.3E-64 T 06-07-2017 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 167 392 2.2E-38 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 SUPERFAMILY SSF88659 302 400 3.74E-28 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 SUPERFAMILY SSF88946 103 241 8.19E-52 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 195 208 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 Pfam PF04545 Sigma-70, region 4 339 392 6.9E-20 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 Gene3D G3DSA:1.10.10.10 333 404 2.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 PRINTS PR00046 Major sigma-70 factor signature 364 379 7.5E-30 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 PRINTS PR00046 Major sigma-70 factor signature 343 355 7.5E-30 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 PRINTS PR00046 Major sigma-70 factor signature 379 390 7.5E-30 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 PRINTS PR00046 Major sigma-70 factor signature 195 208 7.5E-30 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 PRINTS PR00046 Major sigma-70 factor signature 219 227 7.5E-30 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 Pfam PF00140 Sigma-70 factor, region 1.2 106 139 1.8E-16 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 364 390 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 SUPERFAMILY SSF88659 244 317 3.6E-19 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 Gene3D G3DSA:1.10.10.10 244 295 5.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 Pfam PF04542 Sigma-70 region 2 171 240 1.7E-23 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS09170 9834691f09cf4b531d597e76cef6cd62 404 Pfam PF04539 Sigma-70 region 3 250 326 9.7E-28 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS03180 759bf29f3331317565e35f7a3028f20a 665 Gene3D G3DSA:1.10.530.10 40 78 4.0E-5 T 06-07-2017 LK06_RS03180 759bf29f3331317565e35f7a3028f20a 665 Gene3D G3DSA:1.10.530.10 125 214 4.0E-5 T 06-07-2017 LK06_RS03180 759bf29f3331317565e35f7a3028f20a 665 SUPERFAMILY SSF53955 41 94 4.12E-5 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS03180 759bf29f3331317565e35f7a3028f20a 665 Gene3D G3DSA:3.40.80.10 279 429 2.9E-34 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS03180 759bf29f3331317565e35f7a3028f20a 665 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 288 418 4.2E-19 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS03180 759bf29f3331317565e35f7a3028f20a 665 SMART SM00644 280 417 7.1E-36 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS03180 759bf29f3331317565e35f7a3028f20a 665 SUPERFAMILY SSF55846 266 432 1.44E-35 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS18705 593fba39efa2da7795884c63781640e7 464 Pfam PF00989 PAS fold 24 133 3.0E-12 T 06-07-2017 IPR013767 PAS fold GO:0006355 LK06_RS18705 593fba39efa2da7795884c63781640e7 464 SUPERFAMILY SSF55781 352 456 9.81E-6 T 06-07-2017 IPR029016 GAF domain-like LK06_RS18705 593fba39efa2da7795884c63781640e7 464 Gene3D G3DSA:3.30.450.40 283 453 6.9E-11 T 06-07-2017 IPR029016 GAF domain-like LK06_RS18705 593fba39efa2da7795884c63781640e7 464 Pfam PF08448 PAS fold 154 267 9.4E-8 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS18705 593fba39efa2da7795884c63781640e7 464 Pfam PF01590 GAF domain 385 452 6.0E-5 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS18705 593fba39efa2da7795884c63781640e7 464 SUPERFAMILY SSF55785 136 242 8.22E-10 T 06-07-2017 IPR000014 PAS domain LK06_RS18705 593fba39efa2da7795884c63781640e7 464 SUPERFAMILY SSF55785 22 130 3.49E-19 T 06-07-2017 IPR000014 PAS domain LK06_RS18705 593fba39efa2da7795884c63781640e7 464 Gene3D G3DSA:3.30.450.20 22 133 6.7E-18 T 06-07-2017 LK06_RS18705 593fba39efa2da7795884c63781640e7 464 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 143 1.2E-13 T 06-07-2017 IPR000014 PAS domain LK06_RS18705 593fba39efa2da7795884c63781640e7 464 Gene3D G3DSA:3.30.450.20 137 265 3.2E-13 T 06-07-2017 LK06_RS18705 593fba39efa2da7795884c63781640e7 464 SMART SM00091 22 90 2.2E-7 T 06-07-2017 IPR000014 PAS domain LK06_RS18705 593fba39efa2da7795884c63781640e7 464 SMART SM00091 146 211 0.6 T 06-07-2017 IPR000014 PAS domain LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 Gene3D G3DSA:2.30.40.10 14 155 9.8E-45 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 410 425 2.4E-23 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 436 449 2.4E-23 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 304 321 2.4E-23 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 343 359 2.4E-23 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 Hamap MF_01953 Urease subunit alpha [ureC]. 13 574 46.548 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 SUPERFAMILY SSF51556 489 574 2.78E-141 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 SUPERFAMILY SSF51556 142 440 2.78E-141 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 Gene3D G3DSA:3.20.20.140 156 438 2.6E-143 T 06-07-2017 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 Gene3D G3DSA:3.20.20.140 497 573 2.6E-143 T 06-07-2017 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 SUPERFAMILY SSF51338 16 141 8.64E-41 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 SUPERFAMILY SSF51338 431 477 8.64E-41 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 Pfam PF00449 Urease alpha-subunit, N-terminal domain 15 131 3.1E-38 T 06-07-2017 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 Pfam PF01979 Amidohydrolase family 137 458 1.2E-42 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS24040 d142198ad771cae2d5bd0064460b16bd 574 ProSitePatterns PS01120 Urease nickel ligands signature. 139 152 - T 06-07-2017 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS13795 02fcaab3218d69870e4d278b1755555f 201 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 77 93 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 LK06_RS13795 02fcaab3218d69870e4d278b1755555f 201 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 17 199 41.953 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 LK06_RS13795 02fcaab3218d69870e4d278b1755555f 201 SUPERFAMILY SSF55620 14 198 8.89E-78 T 06-07-2017 LK06_RS13795 02fcaab3218d69870e4d278b1755555f 201 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 22 198 1.0E-71 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 LK06_RS13795 02fcaab3218d69870e4d278b1755555f 201 Gene3D G3DSA:3.30.1130.10 70 199 4.5E-59 T 06-07-2017 LK06_RS13795 02fcaab3218d69870e4d278b1755555f 201 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 127 137 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 LK06_RS13795 02fcaab3218d69870e4d278b1755555f 201 Pfam PF01227 GTP cyclohydrolase I 22 198 9.0E-78 T 06-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 LK06_RS13795 02fcaab3218d69870e4d278b1755555f 201 Gene3D G3DSA:1.10.286.10 16 67 1.0E-25 T 06-07-2017 LK06_RS07145 d4dd56f9ef1ef656c91a8b99f8004b4d 200 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 6 200 41.056 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 LK06_RS07145 d4dd56f9ef1ef656c91a8b99f8004b4d 200 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 35 179 1.9E-61 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 LK06_RS07145 d4dd56f9ef1ef656c91a8b99f8004b4d 200 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 65 78 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 LK06_RS07145 d4dd56f9ef1ef656c91a8b99f8004b4d 200 Gene3D G3DSA:3.30.230.40 6 92 4.0E-36 T 06-07-2017 LK06_RS07145 d4dd56f9ef1ef656c91a8b99f8004b4d 200 SUPERFAMILY SSF54211 91 184 5.69E-30 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS07145 d4dd56f9ef1ef656c91a8b99f8004b4d 200 SUPERFAMILY SSF54211 6 89 3.67E-32 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS07145 d4dd56f9ef1ef656c91a8b99f8004b4d 200 Gene3D G3DSA:3.30.230.40 94 200 2.3E-28 T 06-07-2017 LK06_RS07145 d4dd56f9ef1ef656c91a8b99f8004b4d 200 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 161 173 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 LK06_RS12970 8f69a1198479959b937f5a287853dd36 172 Gene3D G3DSA:3.40.630.30 8 166 4.9E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS12970 8f69a1198479959b937f5a287853dd36 172 SUPERFAMILY SSF55729 8 149 6.45E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS12970 8f69a1198479959b937f5a287853dd36 172 Pfam PF13302 Acetyltransferase (GNAT) domain 9 147 6.0E-24 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS11280 9f756dbbd2d1a5f00aaafa05afbfb1b0 522 Pfam PF06271 RDD family 366 517 1.4E-23 T 06-07-2017 IPR010432 RDD LK06_RS11280 9f756dbbd2d1a5f00aaafa05afbfb1b0 522 Pfam PF10708 Protein of unknown function (DUF2510) 16 46 3.7E-9 T 06-07-2017 IPR018929 Domain of unknown function DUF2510 LK06_RS09315 356a7152f1c0978365addb6bcccf9448 278 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 261 6.9E-79 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LK06_RS09315 356a7152f1c0978365addb6bcccf9448 278 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 261 1.2E-75 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LK06_RS09315 356a7152f1c0978365addb6bcccf9448 278 Gene3D G3DSA:3.40.1180.10 31 262 2.6E-94 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LK06_RS09315 356a7152f1c0978365addb6bcccf9448 278 SUPERFAMILY SSF64005 34 257 7.46E-85 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LK06_RS09315 356a7152f1c0978365addb6bcccf9448 278 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 LK06_RS09315 356a7152f1c0978365addb6bcccf9448 278 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 262 39.393 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LK06_RS28950 5326dec1b9d37fcb638585c52e0e408b 263 SUPERFAMILY SSF53790 7 257 1.1E-31 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS28950 5326dec1b9d37fcb638585c52e0e408b 263 Gene3D G3DSA:3.30.950.10 152 259 1.3E-47 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS28950 5326dec1b9d37fcb638585c52e0e408b 263 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 232 3.3E-28 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS28950 5326dec1b9d37fcb638585c52e0e408b 263 TIGRFAM TIGR02434 CobF: precorrin-6A synthase (deacetylating) 8 258 4.9E-111 T 06-07-2017 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 LK06_RS28950 5326dec1b9d37fcb638585c52e0e408b 263 PIRSF PIRSF036525 7 262 1.3E-116 T 06-07-2017 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 LK06_RS28950 5326dec1b9d37fcb638585c52e0e408b 263 Gene3D G3DSA:3.40.1010.10 8 151 7.1E-36 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Gene3D G3DSA:3.30.1490.20 3 109 3.6E-54 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Gene3D G3DSA:3.30.1490.20 198 241 3.6E-54 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Pfam PF00391 PEP-utilising enzyme, mobile domain 418 500 1.4E-23 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Gene3D G3DSA:3.50.30.10 397 503 2.2E-34 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 70 1.1E-11 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 60 285 2.8E-27 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 295 349 7.5E-9 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 SUPERFAMILY SSF51621 533 885 1.32E-112 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 SUPERFAMILY SSF56059 1 374 1.05E-128 T 06-07-2017 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 446 457 - T 06-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 SUPERFAMILY SSF52009 382 509 4.84E-32 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Gene3D G3DSA:3.20.20.60 542 886 3.1E-128 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Gene3D G3DSA:3.30.470.20 242 339 8.8E-34 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 PIRSF PIRSF000853 1 892 0.0 T 06-07-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Gene3D G3DSA:1.10.189.10 340 396 8.0E-20 T 06-07-2017 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 886 0.0 T 06-07-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 534 882 1.7E-86 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 LK06_RS00130 5ab0e125a886cd198f7ccebb56a38821 895 Gene3D G3DSA:1.20.80.30 110 196 9.1E-31 T 06-07-2017 LK06_RS06385 b0f3c589e2335e4b1d0671cb55694a32 265 PIRSF PIRSF002674 2 265 5.6E-68 T 06-07-2017 IPR014403 Vegetative storage protein/acid phosphatase LK06_RS06385 b0f3c589e2335e4b1d0671cb55694a32 265 SUPERFAMILY SSF56784 86 262 2.2E-15 T 06-07-2017 IPR023214 HAD-like domain LK06_RS06385 b0f3c589e2335e4b1d0671cb55694a32 265 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 72 263 3.0E-35 T 06-07-2017 IPR005519 Acid phosphatase, class B-like LK06_RS06385 b0f3c589e2335e4b1d0671cb55694a32 265 Gene3D G3DSA:3.40.50.1000 73 248 3.4E-18 T 06-07-2017 IPR023214 HAD-like domain LK06_RS08215 83e17364ed55a55318f65ccfe0f41229 187 Gene3D G3DSA:1.10.357.10 45 181 7.1E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS08215 83e17364ed55a55318f65ccfe0f41229 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 50 4.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS08215 83e17364ed55a55318f65ccfe0f41229 187 Pfam PF16859 Bacterial transcriptional repressor C-terminal 67 175 5.1E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS08215 83e17364ed55a55318f65ccfe0f41229 187 Gene3D G3DSA:1.10.10.60 1 43 2.6E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS08215 83e17364ed55a55318f65ccfe0f41229 187 SUPERFAMILY SSF46689 3 55 3.99E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS08215 83e17364ed55a55318f65ccfe0f41229 187 SUPERFAMILY SSF48498 67 180 1.06E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS24310 08b2723b9f164a69c12dbe4263431ba0 80 Pfam PF09851 Short C-terminal domain 53 76 2.3E-6 T 06-07-2017 IPR018649 SHOCT domain LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 Pfam PF00072 Response regulator receiver domain 9 120 2.8E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 SUPERFAMILY SSF46894 137 209 6.12E-22 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 SMART SM00421 146 203 1.9E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 Gene3D G3DSA:1.10.10.10 151 209 1.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 6.0E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 Gene3D G3DSA:3.40.50.2300 4 150 6.6E-34 T 06-07-2017 LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 5.0E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 5.0E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 5.0E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 SMART SM00448 6 120 2.4E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS09360 0d9da4e3a21714f482dca9d4ebfd41a2 211 SUPERFAMILY SSF52172 5 140 4.27E-29 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS32070 26cfb9f116461fa01637295a9092f573 237 PIRSF PIRSF000370 3 237 5.6E-48 T 06-07-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 LK06_RS32070 26cfb9f116461fa01637295a9092f573 237 Pfam PF04055 Radical SAM superfamily 31 133 2.8E-12 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS32070 26cfb9f116461fa01637295a9092f573 237 SUPERFAMILY SSF102114 28 127 3.14E-16 T 06-07-2017 LK06_RS32070 26cfb9f116461fa01637295a9092f573 237 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 5 234 37.417 T 06-07-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 LK06_RS32070 26cfb9f116461fa01637295a9092f573 237 Gene3D G3DSA:3.20.20.70 32 137 1.1E-15 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS32070 26cfb9f116461fa01637295a9092f573 237 Pfam PF13394 4Fe-4S single cluster domain 28 124 6.4E-13 T 06-07-2017 LK06_RS28360 1cb7baa012147c618a8d8943526fac5b 209 Gene3D G3DSA:3.40.50.150 40 181 3.4E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28360 1cb7baa012147c618a8d8943526fac5b 209 SUPERFAMILY SSF53335 33 196 2.25E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28360 1cb7baa012147c618a8d8943526fac5b 209 Pfam PF13489 Methyltransferase domain 58 165 1.9E-14 T 06-07-2017 LK06_RS25920 050417eac11bfd2fc5a291065df05b45 421 Pfam PF13579 Glycosyl transferase 4-like domain 28 196 4.1E-19 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS25920 050417eac11bfd2fc5a291065df05b45 421 Pfam PF13692 Glycosyl transferases group 1 219 365 8.1E-23 T 06-07-2017 LK06_RS25920 050417eac11bfd2fc5a291065df05b45 421 SUPERFAMILY SSF53756 28 401 2.65E-59 T 06-07-2017 LK06_RS25920 050417eac11bfd2fc5a291065df05b45 421 Gene3D G3DSA:3.40.50.2000 214 376 6.4E-9 T 06-07-2017 LK06_RS17995 80266b45987e4fbd2020ea7dc0ae9ce9 364 SMART SM00530 6 61 2.4E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS17995 80266b45987e4fbd2020ea7dc0ae9ce9 364 Pfam PF01381 Helix-turn-helix 7 59 1.4E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS17995 80266b45987e4fbd2020ea7dc0ae9ce9 364 SUPERFAMILY SSF47413 4 63 1.74E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS17995 80266b45987e4fbd2020ea7dc0ae9ce9 364 Pfam PF06114 Domain of unknown function (DUF955) 149 239 7.1E-20 T 06-07-2017 IPR010359 HTH domain, IrrE-type LK06_RS17995 80266b45987e4fbd2020ea7dc0ae9ce9 364 Gene3D G3DSA:1.10.260.40 5 65 4.9E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS30595 d25855e69d5dd3cb40279a27b3c3679c 313 SUPERFAMILY SSF50249 3 136 3.6E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS30595 d25855e69d5dd3cb40279a27b3c3679c 313 SUPERFAMILY SSF50249 160 289 1.2E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS30595 d25855e69d5dd3cb40279a27b3c3679c 313 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 187 216 5.0E-7 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal LK06_RS30595 d25855e69d5dd3cb40279a27b3c3679c 313 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 64 127 8.7E-11 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal LK06_RS30595 d25855e69d5dd3cb40279a27b3c3679c 313 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 223 286 2.0E-12 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal LK06_RS18685 0227d71077d925d62ce2d79885662f94 343 SUPERFAMILY SSF51197 6 302 3.91E-82 T 06-07-2017 LK06_RS18685 0227d71077d925d62ce2d79885662f94 343 PRINTS PR00682 Isopenicillin N synthase signature 36 53 1.3E-10 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 LK06_RS18685 0227d71077d925d62ce2d79885662f94 343 PRINTS PR00682 Isopenicillin N synthase signature 243 269 1.3E-10 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 LK06_RS18685 0227d71077d925d62ce2d79885662f94 343 PRINTS PR00682 Isopenicillin N synthase signature 207 228 1.3E-10 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 LK06_RS18685 0227d71077d925d62ce2d79885662f94 343 Gene3D G3DSA:2.60.120.330 11 321 1.7E-90 T 06-07-2017 IPR027443 Isopenicillin N synthase-like LK06_RS18685 0227d71077d925d62ce2d79885662f94 343 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 14 137 3.6E-33 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain LK06_RS18685 0227d71077d925d62ce2d79885662f94 343 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 189 284 4.1E-22 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 LK06_RS04160 bf826b8171ba29999979e1e18d772e13 302 Pfam PF13671 AAA domain 123 256 1.2E-6 T 06-07-2017 LK06_RS04160 bf826b8171ba29999979e1e18d772e13 302 SUPERFAMILY SSF52540 123 293 2.0E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04160 bf826b8171ba29999979e1e18d772e13 302 Gene3D G3DSA:3.40.50.300 123 294 3.8E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09160 89cfdacba3568185afd8e7089e9be0ef 577 SMART SM00382 360 546 8.8E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS09160 89cfdacba3568185afd8e7089e9be0ef 577 SUPERFAMILY SSF90123 6 313 3.01E-72 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS09160 89cfdacba3568185afd8e7089e9be0ef 577 Gene3D G3DSA:3.40.50.300 333 564 3.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09160 89cfdacba3568185afd8e7089e9be0ef 577 SUPERFAMILY SSF52540 327 570 1.1E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09160 89cfdacba3568185afd8e7089e9be0ef 577 Pfam PF00664 ABC transporter transmembrane region 19 288 2.7E-42 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS09160 89cfdacba3568185afd8e7089e9be0ef 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS09160 89cfdacba3568185afd8e7089e9be0ef 577 Pfam PF00005 ABC transporter 351 498 4.5E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS09160 89cfdacba3568185afd8e7089e9be0ef 577 Gene3D G3DSA:1.20.1560.10 6 312 2.3E-65 T 06-07-2017 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 420 1.6E-37 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 Gene3D G3DSA:3.30.70.1050 3 118 1.5E-35 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 157 215 1.5E-7 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 Hamap MF_00303 Trigger factor [tig]. 1 425 19.632 T 06-07-2017 IPR005215 Trigger factor GO:0015031 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 Gene3D G3DSA:1.10.3120.10 211 394 5.6E-45 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 SUPERFAMILY SSF102735 3 131 1.31E-37 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 SUPERFAMILY SSF54534 133 244 7.86E-21 T 06-07-2017 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 Gene3D G3DSA:3.10.50.40 156 210 1.2E-5 T 06-07-2017 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 Pfam PF05697 Bacterial trigger factor protein (TF) 3 145 2.9E-42 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 TIGRFAM TIGR00115 tig: trigger factor 12 418 9.3E-122 T 06-07-2017 IPR005215 Trigger factor GO:0015031 LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 SUPERFAMILY SSF109998 245 434 1.83E-39 T 06-07-2017 IPR027304 Trigger factor/SurA domain LK06_RS09920 0555d8372705f25203f0366c2a680de2 457 PIRSF PIRSF003095 1 446 4.2E-126 T 06-07-2017 IPR005215 Trigger factor GO:0015031 LK06_RS19360 de75b66d06cbf0b6d9307b6708d05a3c 965 Pfam PF01804 Penicillin amidase 69 953 1.9E-238 T 06-07-2017 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 LK06_RS19360 de75b66d06cbf0b6d9307b6708d05a3c 965 Gene3D G3DSA:2.30.120.10 443 526 3.9E-21 T 06-07-2017 LK06_RS19360 de75b66d06cbf0b6d9307b6708d05a3c 965 PIRSF PIRSF001227 27 965 2.6E-288 T 06-07-2017 IPR014395 Penicillin acylase GO:0016811 LK06_RS19360 de75b66d06cbf0b6d9307b6708d05a3c 965 Gene3D G3DSA:1.10.439.10 53 230 2.5E-61 T 06-07-2017 IPR023343 Penicillin amidase type, domain1 GO:0016811 LK06_RS19360 de75b66d06cbf0b6d9307b6708d05a3c 965 SUPERFAMILY SSF56235 349 965 2.44E-208 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS19360 de75b66d06cbf0b6d9307b6708d05a3c 965 SUPERFAMILY SSF56235 65 259 2.44E-208 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS19360 de75b66d06cbf0b6d9307b6708d05a3c 965 Gene3D G3DSA:3.60.20.10 786 803 1.3E-114 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS19360 de75b66d06cbf0b6d9307b6708d05a3c 965 Gene3D G3DSA:3.60.20.10 535 742 1.3E-114 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS19360 de75b66d06cbf0b6d9307b6708d05a3c 965 Gene3D G3DSA:3.60.20.10 361 442 1.3E-114 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 Gene3D G3DSA:3.40.50.20 1 129 1.2E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 SMART SM00878 347 453 3.3E-51 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.9E-44 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 SUPERFAMILY SSF52440 1 113 3.17E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 Gene3D G3DSA:3.30.1490.20 130 201 1.3E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 Gene3D G3DSA:3.30.470.20 203 461 9.7E-93 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 332 2.1E-69 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 Pfam PF00364 Biotin-requiring enzyme 579 644 2.0E-18 T 06-07-2017 IPR000089 Biotin/lipoyl attachment LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 Gene3D G3DSA:2.40.50.100 576 644 3.1E-24 T 06-07-2017 LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 Pfam PF02785 Biotin carboxylase C-terminal domain 347 453 1.4E-33 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 SUPERFAMILY SSF51230 569 644 4.32E-21 T 06-07-2017 IPR011053 Single hybrid motif LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 SUPERFAMILY SSF56059 83 359 4.6E-64 T 06-07-2017 LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 SUPERFAMILY SSF51246 342 459 4.92E-36 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS10720 557c25ec82fd145ffc88461d2268fcb9 655 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 601 618 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 9.0E-14 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 60.049 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 Gene3D G3DSA:2.40.30.10 303 396 1.4E-46 T 06-07-2017 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 397 7.5E-223 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 Gene3D G3DSA:2.40.30.10 211 301 1.8E-37 T 06-07-2017 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 SUPERFAMILY SSF50447 207 304 4.99E-32 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 Pfam PF03143 Elongation factor Tu C-terminal domain 302 395 1.2E-33 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 6.6E-18 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 3.7E-58 T 06-07-2017 LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 SUPERFAMILY SSF52540 6 221 1.19E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 SUPERFAMILY SSF50465 305 397 4.32E-36 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal LK06_RS12400 3a5470e05ebbf3fbde707dd42ee2d7a9 397 Gene3D G3DSA:3.40.50.300 4 210 1.0E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09400 5f3e133f5c91c830f4308d6aaf4a9b5d 445 Pfam PF00909 Ammonium Transporter Family 14 410 5.4E-124 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 LK06_RS09400 5f3e133f5c91c830f4308d6aaf4a9b5d 445 ProSitePatterns PS01219 Ammonium transporters signature. 166 191 - T 06-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 LK06_RS09400 5f3e133f5c91c830f4308d6aaf4a9b5d 445 Gene3D G3DSA:1.10.3430.10 7 390 8.7E-137 T 06-07-2017 IPR029020 Ammonium/urea transporter LK06_RS09400 5f3e133f5c91c830f4308d6aaf4a9b5d 445 SUPERFAMILY SSF111352 8 390 4.84E-125 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 LK06_RS09400 5f3e133f5c91c830f4308d6aaf4a9b5d 445 TIGRFAM TIGR00836 amt: ammonium transporter 12 410 7.5E-140 T 06-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 LK06_RS03825 706613fcc8efb842050dfbb0f0d3c2c5 502 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 71 87 2.3E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS03825 706613fcc8efb842050dfbb0f0d3c2c5 502 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 71 2.3E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS03825 706613fcc8efb842050dfbb0f0d3c2c5 502 Gene3D G3DSA:3.90.1150.10 352 483 5.3E-17 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS03825 706613fcc8efb842050dfbb0f0d3c2c5 502 SMART SM00345 38 97 4.5E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS03825 706613fcc8efb842050dfbb0f0d3c2c5 502 Gene3D G3DSA:1.10.10.10 31 96 1.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03825 706613fcc8efb842050dfbb0f0d3c2c5 502 Pfam PF00155 Aminotransferase class I and II 159 465 1.5E-27 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS03825 706613fcc8efb842050dfbb0f0d3c2c5 502 Gene3D G3DSA:3.40.640.10 134 351 2.7E-43 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS03825 706613fcc8efb842050dfbb0f0d3c2c5 502 SUPERFAMILY SSF53383 120 483 8.78E-72 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS03825 706613fcc8efb842050dfbb0f0d3c2c5 502 SUPERFAMILY SSF46785 30 101 4.77E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03825 706613fcc8efb842050dfbb0f0d3c2c5 502 Pfam PF00392 Bacterial regulatory proteins, gntR family 35 94 1.7E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS29110 8ba93275b3166bd3e66fd158a9719ea1 207 Gene3D G3DSA:3.40.605.10 40 194 1.5E-38 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS29110 8ba93275b3166bd3e66fd158a9719ea1 207 Pfam PF00171 Aldehyde dehydrogenase family 40 194 3.7E-35 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS29110 8ba93275b3166bd3e66fd158a9719ea1 207 SUPERFAMILY SSF53720 34 195 5.76E-35 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS08355 0470079ba19f0e83d4c2c82a607a695c 409 Pfam PF00082 Subtilase family 59 307 6.1E-36 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS08355 0470079ba19f0e83d4c2c82a607a695c 409 PRINTS PR00723 Subtilisin serine protease family (S8) signature 266 282 5.2E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS08355 0470079ba19f0e83d4c2c82a607a695c 409 PRINTS PR00723 Subtilisin serine protease family (S8) signature 59 78 5.2E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS08355 0470079ba19f0e83d4c2c82a607a695c 409 PRINTS PR00723 Subtilisin serine protease family (S8) signature 98 111 5.2E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS08355 0470079ba19f0e83d4c2c82a607a695c 409 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 64 74 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site LK06_RS08355 0470079ba19f0e83d4c2c82a607a695c 409 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 48 406 4.8E-98 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 LK06_RS08355 0470079ba19f0e83d4c2c82a607a695c 409 SUPERFAMILY SSF52743 41 329 4.06E-67 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS08355 0470079ba19f0e83d4c2c82a607a695c 409 Gene3D G3DSA:3.40.50.200 34 326 1.2E-68 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS06985 94a53e656003ffc7f14f0bc6b235af7e 247 SUPERFAMILY SSF52096 7 229 6.07E-53 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS06985 94a53e656003ffc7f14f0bc6b235af7e 247 Gene3D G3DSA:3.90.226.10 9 220 5.6E-53 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS06985 94a53e656003ffc7f14f0bc6b235af7e 247 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 208 4.4E-38 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 362 468 3.6E-25 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 Gene3D G3DSA:3.30.390.30 355 474 4.9E-33 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.8E-53 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 166 1.8E-53 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 193 218 1.8E-53 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 378 1.8E-53 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 292 1.8E-53 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 321 328 1.8E-53 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 437 1.8E-53 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.8E-53 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 464 1.8E-53 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PIRSF PIRSF000350 1 475 2.3E-76 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 Gene3D G3DSA:3.50.50.60 158 349 2.6E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.2E-34 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 306 328 5.2E-34 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 193 211 5.2E-34 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 293 5.2E-34 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 5.2E-34 T 06-07-2017 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 SUPERFAMILY SSF55424 357 475 6.53E-30 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 Gene3D G3DSA:3.50.50.60 6 157 2.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 SUPERFAMILY SSF51905 142 350 5.18E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 SUPERFAMILY SSF51905 4 93 5.18E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20825 ddf2b62be799b1ef7ac56ce4a0ee7019 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 341 6.5E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20910 79a64140a64f0870684ac4ff112037c7 416 Pfam PF03734 L,D-transpeptidase catalytic domain 252 386 8.5E-13 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 LK06_RS20910 79a64140a64f0870684ac4ff112037c7 416 Gene3D G3DSA:2.40.440.10 254 387 3.2E-19 T 06-07-2017 LK06_RS20910 79a64140a64f0870684ac4ff112037c7 416 SUPERFAMILY SSF141523 254 386 1.44E-22 T 06-07-2017 LK06_RS15310 5871b97629a134c1a3255ee7ffd200d1 379 Pfam PF01594 Domain of unknown function DUF20 18 334 7.1E-56 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like LK06_RS01425 1f74b6f8fa1f8a042e7a20483ed1e1b7 237 Gene3D G3DSA:1.20.144.10 39 207 3.7E-25 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS01425 1f74b6f8fa1f8a042e7a20483ed1e1b7 237 SMART SM00014 92 203 1.2E-15 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS01425 1f74b6f8fa1f8a042e7a20483ed1e1b7 237 SUPERFAMILY SSF48317 7 213 5.76E-34 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS01425 1f74b6f8fa1f8a042e7a20483ed1e1b7 237 Pfam PF01569 PAP2 superfamily 116 207 7.8E-16 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS22110 fbba3cbb14a714eb74e39feb30623851 293 SUPERFAMILY SSF53474 18 287 4.74E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22110 fbba3cbb14a714eb74e39feb30623851 293 Gene3D G3DSA:3.40.50.1820 37 287 4.0E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22110 fbba3cbb14a714eb74e39feb30623851 293 Pfam PF12697 Alpha/beta hydrolase family 43 281 5.5E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS04060 ae46bdb4632a3c13b744e90ecbf1e59a 310 Gene3D G3DSA:3.10.25.10 208 309 6.4E-31 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS04060 ae46bdb4632a3c13b744e90ecbf1e59a 310 SUPERFAMILY SSF53328 1 206 2.62E-57 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS04060 ae46bdb4632a3c13b744e90ecbf1e59a 310 Pfam PF02911 Formyl transferase, C-terminal domain 204 300 2.0E-23 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS04060 ae46bdb4632a3c13b744e90ecbf1e59a 310 SUPERFAMILY SSF50486 205 308 2.51E-27 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 LK06_RS04060 ae46bdb4632a3c13b744e90ecbf1e59a 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 301 6.9E-66 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 LK06_RS04060 ae46bdb4632a3c13b744e90ecbf1e59a 310 Gene3D G3DSA:3.40.50.170 1 206 6.8E-60 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS04060 ae46bdb4632a3c13b744e90ecbf1e59a 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 32.695 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 LK06_RS04060 ae46bdb4632a3c13b744e90ecbf1e59a 310 Pfam PF00551 Formyl transferase 2 177 9.8E-33 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LK06_RS27115 4da2efdd3d3225a47280383c14afbed7 260 Gene3D G3DSA:1.25.40.10 58 237 1.9E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS27115 4da2efdd3d3225a47280383c14afbed7 260 SUPERFAMILY SSF48452 96 204 8.06E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS28170 25fa0558f5329223a87ab55e7b8ade20 287 SMART SM00530 18 73 5.4E-4 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS28170 25fa0558f5329223a87ab55e7b8ade20 287 Pfam PF13560 Helix-turn-helix domain 15 75 4.8E-9 T 06-07-2017 LK06_RS28170 25fa0558f5329223a87ab55e7b8ade20 287 Gene3D G3DSA:1.10.260.40 13 71 2.8E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS28170 25fa0558f5329223a87ab55e7b8ade20 287 SUPERFAMILY SSF47413 14 69 5.63E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 Pfam PF00931 NB-ARC domain 183 318 7.7E-8 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 Gene3D G3DSA:1.25.40.10 799 928 1.1E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 Gene3D G3DSA:1.25.40.10 570 721 1.7E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 Gene3D G3DSA:1.25.40.10 767 782 1.7E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 SUPERFAMILY SSF48452 683 722 5.93E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 SUPERFAMILY SSF48452 804 885 5.93E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 SUPERFAMILY SSF52540 170 380 5.33E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 Gene3D G3DSA:3.40.50.300 180 297 3.9E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 Pfam PF13424 Tetratricopeptide repeat 648 719 1.7E-13 T 06-07-2017 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 Pfam PF13374 Tetratricopeptide repeat 814 854 0.0016 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 Pfam PF13374 Tetratricopeptide repeat 860 896 0.0018 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 Pfam PF13374 Tetratricopeptide repeat 736 769 6.9E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 SUPERFAMILY SSF48452 607 719 3.59E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22650 fbc640d74be9debb71b0b8e94fc6dd3e 1000 SUPERFAMILY SSF48452 856 962 1.24E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15405 1c62b05bd3ab28547fe9a5bad98d15b0 548 Gene3D G3DSA:1.10.510.10 101 283 6.8E-44 T 06-07-2017 LK06_RS15405 1c62b05bd3ab28547fe9a5bad98d15b0 548 SMART SM00740 475 543 1.4E-6 T 06-07-2017 IPR005543 PASTA domain LK06_RS15405 1c62b05bd3ab28547fe9a5bad98d15b0 548 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 49 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS15405 1c62b05bd3ab28547fe9a5bad98d15b0 548 Gene3D G3DSA:3.30.200.20 15 100 6.3E-26 T 06-07-2017 LK06_RS15405 1c62b05bd3ab28547fe9a5bad98d15b0 548 Pfam PF03793 PASTA domain 480 542 1.1E-7 T 06-07-2017 IPR005543 PASTA domain LK06_RS15405 1c62b05bd3ab28547fe9a5bad98d15b0 548 SMART SM00220 20 287 1.2E-58 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS15405 1c62b05bd3ab28547fe9a5bad98d15b0 548 SUPERFAMILY SSF56112 16 357 3.91E-73 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS15405 1c62b05bd3ab28547fe9a5bad98d15b0 548 Pfam PF00069 Protein kinase domain 20 280 4.6E-47 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS15405 1c62b05bd3ab28547fe9a5bad98d15b0 548 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 147 159 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS05415 74b249d95ccd3d63c5c38bbde97527a8 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 193 1.1E-24 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS05415 74b249d95ccd3d63c5c38bbde97527a8 197 Gene3D G3DSA:1.10.1740.10 21 127 2.4E-22 T 06-07-2017 LK06_RS05415 74b249d95ccd3d63c5c38bbde97527a8 197 Pfam PF04542 Sigma-70 region 2 44 105 1.1E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS05415 74b249d95ccd3d63c5c38bbde97527a8 197 Pfam PF08281 Sigma-70, region 4 136 189 1.1E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS05415 74b249d95ccd3d63c5c38bbde97527a8 197 Gene3D G3DSA:1.10.10.10 131 194 3.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05415 74b249d95ccd3d63c5c38bbde97527a8 197 SUPERFAMILY SSF88946 21 116 4.71E-21 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS05415 74b249d95ccd3d63c5c38bbde97527a8 197 SUPERFAMILY SSF88659 129 194 3.49E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS04935 a589d2b7abda3aec9ca40fe5e830c1ad 141 Gene3D G3DSA:1.10.10.10 66 118 4.2E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04935 a589d2b7abda3aec9ca40fe5e830c1ad 141 Pfam PF05331 Protein of unknown function (DUF742) 35 141 2.2E-31 T 06-07-2017 IPR007995 Protein of unknown function DUF742 LK06_RS23290 069441203622350e01269591a2114d14 271 Gene3D G3DSA:1.10.520.20 108 198 1.0E-5 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 LK06_RS23290 069441203622350e01269591a2114d14 271 Hamap MF_01416 ATP synthase subunit delta [atpD]. 87 271 14.558 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 LK06_RS23290 069441203622350e01269591a2114d14 271 PRINTS PR00125 ATP synthase delta subunit signature 244 262 3.6E-6 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 LK06_RS23290 069441203622350e01269591a2114d14 271 PRINTS PR00125 ATP synthase delta subunit signature 229 244 3.6E-6 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 LK06_RS23290 069441203622350e01269591a2114d14 271 SUPERFAMILY SSF47928 109 198 9.68E-5 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 LK06_RS23290 069441203622350e01269591a2114d14 271 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 231 250 - T 06-07-2017 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 LK06_RS23290 069441203622350e01269591a2114d14 271 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 110 267 8.8E-19 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 LK06_RS23290 069441203622350e01269591a2114d14 271 Pfam PF00213 ATP synthase delta (OSCP) subunit 109 268 8.4E-33 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 7.5E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 7.5E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 7.5E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 9.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 9.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 9.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 9.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 9.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 9.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 Gene3D G3DSA:3.40.50.720 15 257 2.4E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 256 3.1E-61 T 06-07-2017 LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 SUPERFAMILY SSF51735 17 257 1.86E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS07015 5ee070f40976d62410f55a211d4a5892 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 Gene3D G3DSA:3.40.120.10 4 158 1.4E-41 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 SUPERFAMILY SSF53738 4 185 5.1E-43 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 374 8.4E-33 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 448 1.8E-171 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 Gene3D G3DSA:3.40.120.10 256 373 9.9E-34 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 4.5E-38 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 SUPERFAMILY SSF53738 263 370 1.49E-30 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 447 2.4E-14 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 SUPERFAMILY SSF53738 163 261 1.1E-26 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 164 259 6.0E-18 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 450 44.015 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 SUPERFAMILY SSF55957 364 452 3.53E-23 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 Gene3D G3DSA:3.30.310.50 375 450 1.2E-18 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 Gene3D G3DSA:3.40.120.10 181 255 8.9E-25 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 2.5E-11 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 2.5E-11 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS12145 8f8c93a10ee0c99ce60f03a675ee52b8 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 2.5E-11 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS13525 ea3ee99e987b28a95f2b5fc70c80b024 270 Gene3D G3DSA:1.10.3730.10 159 264 5.0E-41 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LK06_RS13525 ea3ee99e987b28a95f2b5fc70c80b024 270 Gene3D G3DSA:3.40.50.720 2 157 1.8E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13525 ea3ee99e987b28a95f2b5fc70c80b024 270 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 97 6.3E-22 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal LK06_RS13525 ea3ee99e987b28a95f2b5fc70c80b024 270 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 LK06_RS13525 ea3ee99e987b28a95f2b5fc70c80b024 270 PIRSF PIRSF000193 2 267 2.3E-76 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 LK06_RS13525 ea3ee99e987b28a95f2b5fc70c80b024 270 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 264 3.3E-81 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 LK06_RS13525 ea3ee99e987b28a95f2b5fc70c80b024 270 SUPERFAMILY SSF48179 159 265 1.11E-35 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS13525 ea3ee99e987b28a95f2b5fc70c80b024 270 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 6.9E-38 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LK06_RS13525 ea3ee99e987b28a95f2b5fc70c80b024 270 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 264 26.797 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 LK06_RS13525 ea3ee99e987b28a95f2b5fc70c80b024 270 SUPERFAMILY SSF51735 4 158 2.89E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 Pfam PF13549 ATP-grasp domain 672 882 1.1E-59 T 06-07-2017 LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 SMART SM00881 195 290 1.6E-29 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 Pfam PF00583 Acetyltransferase (GNAT) family 77 152 1.3E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 SUPERFAMILY SSF52210 315 476 3.79E-33 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 Gene3D G3DSA:3.40.50.720 186 314 5.3E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 Pfam PF13380 CoA binding domain 200 318 8.0E-21 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 SUPERFAMILY SSF55729 17 160 1.13E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 SUPERFAMILY SSF52210 480 638 9.55E-23 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 Gene3D G3DSA:3.40.50.261 471 626 3.9E-10 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 Gene3D G3DSA:3.40.50.261 315 470 8.9E-26 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 Gene3D G3DSA:3.40.630.30 15 165 3.4E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 337 474 9.2E-42 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 SUPERFAMILY SSF51735 190 320 3.8E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS30220 a3d55990c0f0883273192e30a90d7d4e 896 SUPERFAMILY SSF56059 677 880 1.15E-29 T 06-07-2017 LK06_RS31840 c7a66f52e99c028baa8bac03a43f1130 51 SUPERFAMILY SSF54506 2 49 9.03E-7 T 06-07-2017 LK06_RS31840 c7a66f52e99c028baa8bac03a43f1130 51 Gene3D G3DSA:3.10.310.10 1 46 4.0E-7 T 06-07-2017 LK06_RS29750 f1e885ad9359fdb14b4327af5a78504d 539 Gene3D G3DSA:3.40.50.980 227 379 1.1E-36 T 06-07-2017 LK06_RS29750 f1e885ad9359fdb14b4327af5a78504d 539 Gene3D G3DSA:3.30.300.30 441 536 3.8E-28 T 06-07-2017 LK06_RS29750 f1e885ad9359fdb14b4327af5a78504d 539 Gene3D G3DSA:3.40.50.980 73 226 1.8E-21 T 06-07-2017 LK06_RS29750 f1e885ad9359fdb14b4327af5a78504d 539 SUPERFAMILY SSF56801 67 537 1.83E-109 T 06-07-2017 LK06_RS29750 f1e885ad9359fdb14b4327af5a78504d 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 526 1.7E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS29750 f1e885ad9359fdb14b4327af5a78504d 539 Pfam PF00501 AMP-binding enzyme 73 444 2.1E-63 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS29750 f1e885ad9359fdb14b4327af5a78504d 539 Gene3D G3DSA:2.30.38.10 397 437 9.9E-7 T 06-07-2017 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 SUPERFAMILY SSF54211 635 813 6.45E-52 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 387 523 4.0E-20 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 Gene3D G3DSA:3.40.50.300 321 534 1.7E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 11 201 3.5E-16 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 SUPERFAMILY SSF88697 11 201 2.09E-21 T 06-07-2017 IPR015947 PUA-like domain LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 SMART SM00464 11 202 9.4E-18 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 769 787 6.3E-50 T 06-07-2017 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 716 735 6.3E-50 T 06-07-2017 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 390 409 6.3E-50 T 06-07-2017 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 635 651 6.3E-50 T 06-07-2017 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 746 765 6.3E-50 T 06-07-2017 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 SMART SM00382 382 527 1.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 SUPERFAMILY SSF52540 319 611 6.74E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 605 815 5.5E-76 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 Gene3D G3DSA:1.10.8.60 535 618 7.3E-27 T 06-07-2017 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 Gene3D G3DSA:3.30.230.10 630 814 2.5E-69 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 719 727 - T 06-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 PIRSF PIRSF001174 1 817 9.7E-237 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 LK06_RS22680 278155bfb265521f79c19d54e6a33827 829 TIGRFAM TIGR00763 lon: endopeptidase La 13 814 2.2E-231 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 LK06_RS22240 5574f9e04d4035d7bd5973af878cfbc8 122 Pfam PF02467 Transcription factor WhiB 49 97 8.5E-15 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS22240 5574f9e04d4035d7bd5973af878cfbc8 122 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 27 111 14.647 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS22240 5574f9e04d4035d7bd5973af878cfbc8 122 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 107 117 - T 06-07-2017 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 LK06_RS05650 0a73b1a88cd26e4791c5727b3c3b3e57 361 Gene3D G3DSA:3.40.50.720 4 171 3.0E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05650 0a73b1a88cd26e4791c5727b3c3b3e57 361 SUPERFAMILY SSF55021 294 354 2.58E-5 T 06-07-2017 LK06_RS05650 0a73b1a88cd26e4791c5727b3c3b3e57 361 Pfam PF02153 Prephenate dehydrogenase 17 251 3.6E-58 T 06-07-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 LK06_RS05650 0a73b1a88cd26e4791c5727b3c3b3e57 361 SUPERFAMILY SSF51735 5 159 4.33E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05650 0a73b1a88cd26e4791c5727b3c3b3e57 361 SUPERFAMILY SSF48179 166 251 7.37E-23 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS16970 a82213f16db60ea19fc536047f1e9325 299 SUPERFAMILY SSF56104 13 298 1.37E-97 T 06-07-2017 LK06_RS16970 a82213f16db60ea19fc536047f1e9325 299 Pfam PF01259 SAICAR synthetase 18 269 8.5E-101 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS16970 a82213f16db60ea19fc536047f1e9325 299 Gene3D G3DSA:3.30.200.20 11 115 1.8E-41 T 06-07-2017 LK06_RS16970 a82213f16db60ea19fc536047f1e9325 299 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS16970 a82213f16db60ea19fc536047f1e9325 299 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 19 298 6.3E-70 T 06-07-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 LK06_RS16970 a82213f16db60ea19fc536047f1e9325 299 Gene3D G3DSA:3.30.470.20 116 247 8.6E-55 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS16970 a82213f16db60ea19fc536047f1e9325 299 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS16970 a82213f16db60ea19fc536047f1e9325 299 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 16 295 25.075 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS08735 ed6d9b66b6131d3d8957de2bc672442d 697 Pfam PF00905 Penicillin binding protein transpeptidase domain 404 658 2.8E-13 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS08735 ed6d9b66b6131d3d8957de2bc672442d 697 Pfam PF00912 Transglycosylase 124 300 2.7E-58 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 LK06_RS08735 ed6d9b66b6131d3d8957de2bc672442d 697 SUPERFAMILY SSF53955 113 322 7.59E-65 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS08735 ed6d9b66b6131d3d8957de2bc672442d 697 Gene3D G3DSA:1.10.3810.10 125 302 9.3E-63 T 06-07-2017 LK06_RS08735 ed6d9b66b6131d3d8957de2bc672442d 697 SUPERFAMILY SSF56601 285 304 7.66E-54 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS08735 ed6d9b66b6131d3d8957de2bc672442d 697 SUPERFAMILY SSF56601 334 664 7.66E-54 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS08735 ed6d9b66b6131d3d8957de2bc672442d 697 Gene3D G3DSA:3.40.710.10 303 664 9.9E-69 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS26555 fe0db414ad1a379e14a737e133a27eea 260 SMART SM00382 31 220 3.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS26555 fe0db414ad1a379e14a737e133a27eea 260 SUPERFAMILY SSF52540 5 221 8.7E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26555 fe0db414ad1a379e14a737e133a27eea 260 Gene3D G3DSA:3.40.50.300 4 220 2.7E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26555 fe0db414ad1a379e14a737e133a27eea 260 Pfam PF00005 ABC transporter 22 172 1.4E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS08275 2673cd0648c6ef4ac8ec9cbfc19406e0 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 283 2.4E-91 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 LK06_RS08275 2673cd0648c6ef4ac8ec9cbfc19406e0 285 SUPERFAMILY SSF55920 7 284 1.7E-86 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS08275 2673cd0648c6ef4ac8ec9cbfc19406e0 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 8.6E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase LK06_RS08275 2673cd0648c6ef4ac8ec9cbfc19406e0 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 8.6E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase LK06_RS08275 2673cd0648c6ef4ac8ec9cbfc19406e0 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 8.6E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase LK06_RS08275 2673cd0648c6ef4ac8ec9cbfc19406e0 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 8.6E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase LK06_RS08275 2673cd0648c6ef4ac8ec9cbfc19406e0 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.576 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 LK06_RS08275 2673cd0648c6ef4ac8ec9cbfc19406e0 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 LK06_RS08275 2673cd0648c6ef4ac8ec9cbfc19406e0 285 Pfam PF00557 Metallopeptidase family M24 48 276 2.9E-53 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS08275 2673cd0648c6ef4ac8ec9cbfc19406e0 285 Gene3D G3DSA:3.90.230.10 41 284 4.2E-97 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS13495 42efdae748a98e3355f871c7d963d965 214 Gene3D G3DSA:3.40.50.1000 1 17 3.4E-41 T 06-07-2017 IPR023214 HAD-like domain LK06_RS13495 42efdae748a98e3355f871c7d963d965 214 Gene3D G3DSA:3.40.50.1000 89 213 3.4E-41 T 06-07-2017 IPR023214 HAD-like domain LK06_RS13495 42efdae748a98e3355f871c7d963d965 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 185 3.7E-26 T 06-07-2017 IPR023214 HAD-like domain LK06_RS13495 42efdae748a98e3355f871c7d963d965 214 SUPERFAMILY SSF56784 2 213 3.64E-52 T 06-07-2017 IPR023214 HAD-like domain LK06_RS13495 42efdae748a98e3355f871c7d963d965 214 Gene3D G3DSA:1.10.150.240 18 84 1.9E-13 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 LK06_RS13495 42efdae748a98e3355f871c7d963d965 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 63 186 2.0E-15 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS06570 d21e7e7b9c4da2ecccb6cd86d7bd79e4 442 SUPERFAMILY SSF53850 40 440 3.66E-59 T 06-07-2017 LK06_RS06570 d21e7e7b9c4da2ecccb6cd86d7bd79e4 442 Gene3D G3DSA:3.40.190.10 171 366 2.0E-30 T 06-07-2017 LK06_RS06570 d21e7e7b9c4da2ecccb6cd86d7bd79e4 442 Pfam PF01547 Bacterial extracellular solute-binding protein 52 351 1.3E-26 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 LK06_RS06570 d21e7e7b9c4da2ecccb6cd86d7bd79e4 442 Gene3D G3DSA:3.40.190.10 49 170 5.0E-22 T 06-07-2017 LK06_RS13985 9f788e780e1f4b7e076d3b4810f4ab57 1144 SUPERFAMILY SSF103473 210 479 2.09E-9 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS13985 9f788e780e1f4b7e076d3b4810f4ab57 1144 Gene3D G3DSA:3.40.50.300 509 706 2.8E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13985 9f788e780e1f4b7e076d3b4810f4ab57 1144 Hamap MF_00165 Thymidylate kinase [tmk]. 510 709 30.929 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 LK06_RS13985 9f788e780e1f4b7e076d3b4810f4ab57 1144 SUPERFAMILY SSF52540 508 709 1.94E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13985 9f788e780e1f4b7e076d3b4810f4ab57 1144 ProSitePatterns PS01331 Thymidylate kinase signature. 599 611 - T 06-07-2017 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 LK06_RS13985 9f788e780e1f4b7e076d3b4810f4ab57 1144 Gene3D G3DSA:1.20.1250.20 294 481 3.5E-12 T 06-07-2017 LK06_RS13985 9f788e780e1f4b7e076d3b4810f4ab57 1144 Pfam PF02223 Thymidylate kinase 514 699 6.1E-47 T 06-07-2017 LK06_RS13985 9f788e780e1f4b7e076d3b4810f4ab57 1144 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 509 699 4.0E-51 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 LK06_RS03365 8f5510a144e4e375ba6300883c513cf2 144 SUPERFAMILY SSF55729 10 136 7.09E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS03365 8f5510a144e4e375ba6300883c513cf2 144 Gene3D G3DSA:3.40.630.30 5 134 1.2E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS03365 8f5510a144e4e375ba6300883c513cf2 144 Pfam PF00583 Acetyltransferase (GNAT) family 53 130 5.0E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS21960 99f5567e4a568dadc91f770ad47447ce 385 SUPERFAMILY SSF55729 166 356 6.2E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS21960 99f5567e4a568dadc91f770ad47447ce 385 Pfam PF00583 Acetyltransferase (GNAT) family 292 347 3.7E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS21960 99f5567e4a568dadc91f770ad47447ce 385 Gene3D G3DSA:3.40.630.30 225 361 9.5E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS07525 308172f996c36fdc626a3097387b12ba 317 Gene3D G3DSA:3.30.420.40 135 286 8.9E-49 T 06-07-2017 LK06_RS07525 308172f996c36fdc626a3097387b12ba 317 SUPERFAMILY SSF53067 2 312 2.26E-68 T 06-07-2017 LK06_RS07525 308172f996c36fdc626a3097387b12ba 317 Gene3D G3DSA:3.30.420.40 1 134 2.7E-47 T 06-07-2017 LK06_RS07525 308172f996c36fdc626a3097387b12ba 317 Pfam PF00480 ROK family 4 312 8.6E-108 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS07525 308172f996c36fdc626a3097387b12ba 317 ProSitePatterns PS01125 ROK family signature. 130 157 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS07525 308172f996c36fdc626a3097387b12ba 317 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 5 312 1.9E-147 T 06-07-2017 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 LK06_RS01860 c9ca5f91d3d6f36002f286dfb625f7ac 183 SUPERFAMILY SSF55874 24 129 4.63E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01860 c9ca5f91d3d6f36002f286dfb625f7ac 183 Pfam PF13581 Histidine kinase-like ATPase domain 5 122 2.1E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01860 c9ca5f91d3d6f36002f286dfb625f7ac 183 Gene3D G3DSA:3.30.565.10 14 126 7.7E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS31875 ec66225f89d8f210e23e5d6ab0c993f5 215 Pfam PF01476 LysM domain 161 209 2.4E-9 T 06-07-2017 IPR018392 LysM domain LK06_RS31875 ec66225f89d8f210e23e5d6ab0c993f5 215 SMART SM00257 160 209 7.6E-11 T 06-07-2017 IPR018392 LysM domain LK06_RS31875 ec66225f89d8f210e23e5d6ab0c993f5 215 Gene3D G3DSA:3.10.350.10 159 210 4.1E-12 T 06-07-2017 IPR018392 LysM domain LK06_RS31875 ec66225f89d8f210e23e5d6ab0c993f5 215 SUPERFAMILY SSF53955 42 122 2.56E-32 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS31875 ec66225f89d8f210e23e5d6ab0c993f5 215 Gene3D G3DSA:1.10.530.10 28 124 4.8E-42 T 06-07-2017 LK06_RS31875 ec66225f89d8f210e23e5d6ab0c993f5 215 SUPERFAMILY SSF54106 159 209 6.93E-7 T 06-07-2017 IPR018392 LysM domain LK06_RS31875 ec66225f89d8f210e23e5d6ab0c993f5 215 Pfam PF06737 Transglycosylase-like domain 42 118 8.6E-36 T 06-07-2017 IPR010618 Transglycosylase-like LK06_RS18680 fe8bfd7fc937a06968540c1a2061bc11 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 1.0E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS18680 fe8bfd7fc937a06968540c1a2061bc11 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS18680 fe8bfd7fc937a06968540c1a2061bc11 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS18680 fe8bfd7fc937a06968540c1a2061bc11 200 SUPERFAMILY SSF46689 10 86 4.99E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS18680 fe8bfd7fc937a06968540c1a2061bc11 200 Gene3D G3DSA:1.10.357.10 7 199 3.5E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS02805 5abf67ad2e7dc7d0b1ab0954db1cb4db 120 Gene3D G3DSA:3.60.10.10 2 102 3.5E-14 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS02805 5abf67ad2e7dc7d0b1ab0954db1cb4db 120 SUPERFAMILY SSF56219 2 102 6.81E-11 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS18225 95e981570f035b1af0e815120feea2d4 163 SUPERFAMILY SSF50475 1 162 2.55E-35 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS18225 95e981570f035b1af0e815120feea2d4 163 Pfam PF01613 Flavin reductase like domain 1 162 9.3E-39 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS18225 95e981570f035b1af0e815120feea2d4 163 Gene3D G3DSA:2.30.110.10 1 163 1.5E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS18225 95e981570f035b1af0e815120feea2d4 163 SMART SM00903 1 161 2.6E-49 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 Pfam PF00128 Alpha amylase, catalytic domain 46 402 7.8E-79 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 SUPERFAMILY SSF51445 34 481 3.1E-136 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 SUPERFAMILY SSF51011 485 561 2.57E-17 T 06-07-2017 LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 Gene3D G3DSA:2.60.40.1180 481 561 9.9E-15 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 561 4.0E-303 T 06-07-2017 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 558 1.1E-26 T 06-07-2017 IPR032091 Maltogenic Amylase, C-terminal LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 SMART SM00642 31 433 2.2E-123 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 Gene3D G3DSA:3.20.20.80 198 427 1.5E-111 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 Gene3D G3DSA:3.20.20.80 460 474 1.5E-111 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 Gene3D G3DSA:3.20.20.80 25 122 1.5E-111 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS30970 adb428c24396c30f0d4fbd54ed96aea1 572 Gene3D G3DSA:3.90.400.10 123 190 4.0E-25 T 06-07-2017 LK06_RS12275 3aa4b0904f02178789cbd3db0f719ebf 74 SUPERFAMILY SSF46561 5 67 3.27E-24 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12275 3aa4b0904f02178789cbd3db0f719ebf 74 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 06-07-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12275 3aa4b0904f02178789cbd3db0f719ebf 74 Gene3D G3DSA:1.10.287.310 6 69 1.2E-31 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12275 3aa4b0904f02178789cbd3db0f719ebf 74 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 18.072 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12275 3aa4b0904f02178789cbd3db0f719ebf 74 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 2.5E-22 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12275 3aa4b0904f02178789cbd3db0f719ebf 74 Pfam PF00831 Ribosomal L29 protein 8 64 2.3E-26 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS08670 5fd0351b7eab908cd494adc34b6fb330 266 Pfam PF00459 Inositol monophosphatase family 11 259 1.4E-28 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS08670 5fd0351b7eab908cd494adc34b6fb330 266 Gene3D G3DSA:3.30.540.10 9 127 1.3E-21 T 06-07-2017 LK06_RS08670 5fd0351b7eab908cd494adc34b6fb330 266 SUPERFAMILY SSF56655 9 262 2.23E-40 T 06-07-2017 LK06_RS08670 5fd0351b7eab908cd494adc34b6fb330 266 Gene3D G3DSA:3.40.190.80 185 261 4.1E-12 T 06-07-2017 LK06_RS08670 5fd0351b7eab908cd494adc34b6fb330 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 3.1E-12 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS08670 5fd0351b7eab908cd494adc34b6fb330 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 3.1E-12 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS08670 5fd0351b7eab908cd494adc34b6fb330 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 3.1E-12 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS12745 47c70540b04e7f73f104ffa3b42375fc 336 Pfam PF00348 Polyprenyl synthetase 42 257 4.6E-57 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS12745 47c70540b04e7f73f104ffa3b42375fc 336 SUPERFAMILY SSF48576 20 334 4.75E-81 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS12745 47c70540b04e7f73f104ffa3b42375fc 336 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS12745 47c70540b04e7f73f104ffa3b42375fc 336 Gene3D G3DSA:1.10.600.10 17 334 6.0E-89 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS24435 c7e604b48b4174ae1153de56ca50660c 233 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 44 208 3.3E-38 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24435 c7e604b48b4174ae1153de56ca50660c 233 ProSitePatterns PS00761 Signal peptidases I signature 3. 167 180 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 LK06_RS24435 c7e604b48b4174ae1153de56ca50660c 233 SUPERFAMILY SSF51306 58 214 4.13E-43 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C LK06_RS24435 c7e604b48b4174ae1153de56ca50660c 233 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 162 181 9.6E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24435 c7e604b48b4174ae1153de56ca50660c 233 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 59 75 9.6E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24435 c7e604b48b4174ae1153de56ca50660c 233 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 113 125 9.6E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24435 c7e604b48b4174ae1153de56ca50660c 233 Pfam PF00717 Peptidase S24-like 65 137 3.1E-15 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B LK06_RS24435 c7e604b48b4174ae1153de56ca50660c 233 Gene3D G3DSA:2.10.109.10 162 217 6.1E-37 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS24435 c7e604b48b4174ae1153de56ca50660c 233 Gene3D G3DSA:2.10.109.10 56 123 6.1E-37 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS21870 9d7b93cb8220df853dbd1067cbbb28ad 326 SUPERFAMILY SSF161098 102 312 2.09E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21870 9d7b93cb8220df853dbd1067cbbb28ad 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 324 7.6E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21870 9d7b93cb8220df853dbd1067cbbb28ad 326 Gene3D G3DSA:1.10.3720.10 101 320 1.6E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS14185 9023d995f5981091262956f7364170a6 155 Gene3D G3DSA:1.10.10.410 95 154 6.0E-21 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal LK06_RS14185 9023d995f5981091262956f7364170a6 155 SUPERFAMILY SSF89095 4 154 4.71E-36 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 LK06_RS14185 9023d995f5981091262956f7364170a6 155 Gene3D G3DSA:1.10.1510.10 4 94 2.3E-26 T 06-07-2017 LK06_RS14185 9023d995f5981091262956f7364170a6 155 Pfam PF09424 Yqey-like protein 6 153 5.2E-47 T 06-07-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial LK06_RS04375 578287a5b7ae32c6f98eac0c69286c4e 118 Pfam PF13936 Helix-turn-helix domain 65 107 9.0E-7 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain LK06_RS04375 578287a5b7ae32c6f98eac0c69286c4e 118 Pfam PF13384 Homeodomain-like domain 27 58 1.3E-5 T 06-07-2017 LK06_RS04375 578287a5b7ae32c6f98eac0c69286c4e 118 Gene3D G3DSA:1.10.10.60 31 58 1.0E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS04375 578287a5b7ae32c6f98eac0c69286c4e 118 Gene3D G3DSA:1.10.10.60 65 100 9.2E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS09365 22af99b022a802bf1b01bd6063e7791f 231 SUPERFAMILY SSF158682 90 224 8.76E-9 T 06-07-2017 IPR029024 TerB-like LK06_RS09365 22af99b022a802bf1b01bd6063e7791f 231 Pfam PF05099 Tellurite resistance protein TerB 94 222 1.2E-8 T 06-07-2017 IPR007791 Co-chaperone DjlA, N-terminal LK06_RS09365 22af99b022a802bf1b01bd6063e7791f 231 Gene3D G3DSA:1.10.3680.10 96 224 7.0E-6 T 06-07-2017 IPR029024 TerB-like LK06_RS26895 67bb6ac4dcd73e19ecb36ad07cc9acc2 237 Pfam PF00929 Exonuclease 10 178 5.3E-12 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III LK06_RS26895 67bb6ac4dcd73e19ecb36ad07cc9acc2 237 SMART SM00479 7 188 1.3E-18 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III LK06_RS26895 67bb6ac4dcd73e19ecb36ad07cc9acc2 237 SUPERFAMILY SSF53098 4 201 1.43E-42 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS26895 67bb6ac4dcd73e19ecb36ad07cc9acc2 237 Gene3D G3DSA:3.30.420.10 3 187 2.7E-39 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS21015 c26db14e7410ccb855bd9342a4fb1700 56 Gene3D G3DSA:3.40.30.10 20 54 8.0E-9 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS21015 c26db14e7410ccb855bd9342a4fb1700 56 Pfam PF03190 Protein of unknown function, DUF255 3 54 6.5E-25 T 06-07-2017 IPR004879 Domain of unknown function DUF255 LK06_RS21015 c26db14e7410ccb855bd9342a4fb1700 56 SUPERFAMILY SSF52833 1 55 2.08E-12 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS13840 b5febe722f3d03b5c97b7f51c6ab4eae 121 Pfam PF01906 Putative heavy-metal-binding 16 117 4.0E-33 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 LK06_RS13840 b5febe722f3d03b5c97b7f51c6ab4eae 121 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 16 118 21.591 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 LK06_RS13840 b5febe722f3d03b5c97b7f51c6ab4eae 121 SUPERFAMILY SSF117782 17 118 1.83E-31 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 LK06_RS13840 b5febe722f3d03b5c97b7f51c6ab4eae 121 Gene3D G3DSA:3.30.110.70 17 117 2.8E-32 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 LK06_RS15455 24d48216498962c02815321b4d754b5b 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 16 63 2.6E-14 T 06-07-2017 LK06_RS15455 24d48216498962c02815321b4d754b5b 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 16 32 8.3E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS15455 24d48216498962c02815321b4d754b5b 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 43 8.3E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS15455 24d48216498962c02815321b4d754b5b 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 62 8.3E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS15455 24d48216498962c02815321b4d754b5b 160 SMART SM00344 16 122 5.9E-26 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS15455 24d48216498962c02815321b4d754b5b 160 SUPERFAMILY SSF54909 78 153 2.15E-13 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS15455 24d48216498962c02815321b4d754b5b 160 SUPERFAMILY SSF46785 16 75 2.39E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15455 24d48216498962c02815321b4d754b5b 160 Pfam PF01037 Lrp/AsnC ligand binding domain 90 153 1.9E-11 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS15455 24d48216498962c02815321b4d754b5b 160 Gene3D G3DSA:3.30.70.920 68 153 3.0E-20 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS15455 24d48216498962c02815321b4d754b5b 160 Gene3D G3DSA:1.10.10.10 15 67 1.4E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30330 02b837dbe955dabe89ee3e7478dd5946 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 18.463 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LK06_RS30330 02b837dbe955dabe89ee3e7478dd5946 124 TIGRFAM TIGR00494 crcB: protein CrcB 4 118 1.6E-25 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LK06_RS30330 02b837dbe955dabe89ee3e7478dd5946 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 115 5.8E-23 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LK06_RS18250 105589a99a0ad087b2e3ea996d05b1e0 304 SUPERFAMILY SSF53067 5 303 2.03E-57 T 06-07-2017 LK06_RS18250 105589a99a0ad087b2e3ea996d05b1e0 304 Gene3D G3DSA:3.30.420.40 3 143 5.3E-36 T 06-07-2017 LK06_RS18250 105589a99a0ad087b2e3ea996d05b1e0 304 Pfam PF00480 ROK family 6 302 4.6E-63 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS18250 105589a99a0ad087b2e3ea996d05b1e0 304 Gene3D G3DSA:3.30.420.40 144 285 2.7E-48 T 06-07-2017 LK06_RS18780 f6708fd23e0911bd776235d0ddff9f35 505 Pfam PF00501 AMP-binding enzyme 20 400 4.2E-65 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS18780 f6708fd23e0911bd776235d0ddff9f35 505 Gene3D G3DSA:2.30.38.10 332 393 9.8E-13 T 06-07-2017 LK06_RS18780 f6708fd23e0911bd776235d0ddff9f35 505 Gene3D G3DSA:3.40.50.980 12 174 8.1E-26 T 06-07-2017 LK06_RS18780 f6708fd23e0911bd776235d0ddff9f35 505 Pfam PF13193 AMP-binding enzyme C-terminal domain 409 482 2.8E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS18780 f6708fd23e0911bd776235d0ddff9f35 505 Gene3D G3DSA:3.30.300.30 395 496 1.9E-22 T 06-07-2017 LK06_RS18780 f6708fd23e0911bd776235d0ddff9f35 505 Gene3D G3DSA:3.40.50.980 175 324 1.1E-25 T 06-07-2017 LK06_RS18780 f6708fd23e0911bd776235d0ddff9f35 505 SUPERFAMILY SSF56801 12 499 5.63E-109 T 06-07-2017 LK06_RS07910 32fd3193812e76513d418c04a1f5d36f 422 Gene3D G3DSA:3.40.47.10 2 262 3.4E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07910 32fd3193812e76513d418c04a1f5d36f 422 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 260 374 4.1E-34 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS07910 32fd3193812e76513d418c04a1f5d36f 422 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 160 176 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS07910 32fd3193812e76513d418c04a1f5d36f 422 Gene3D G3DSA:3.40.47.10 271 417 2.0E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07910 32fd3193812e76513d418c04a1f5d36f 422 SUPERFAMILY SSF53901 3 257 3.58E-68 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07910 32fd3193812e76513d418c04a1f5d36f 422 SUPERFAMILY SSF53901 219 417 1.96E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07910 32fd3193812e76513d418c04a1f5d36f 422 SMART SM00825 Beta-ketoacyl synthase 5 408 5.9E-14 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS07910 32fd3193812e76513d418c04a1f5d36f 422 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 252 1.6E-55 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 381 1.2E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 SUPERFAMILY SSF55874 211 379 6.29E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 Gene3D G3DSA:3.30.565.10 208 380 1.2E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 SMART SM00387 266 382 2.2E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 SMART SM00388 155 221 4.6E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 3.8E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 335 3.8E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 379 3.8E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 321 3.8E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 156 219 8.6E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 Gene3D G3DSA:1.10.287.130 147 207 2.5E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS17840 76ddb3721199601806fd70658b3fb7cb 416 SUPERFAMILY SSF47384 138 221 1.08E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS22275 eed4f83b79a9e4b7193ea0f0079353a2 251 Gene3D G3DSA:3.60.160.10 15 225 1.6E-33 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS22275 eed4f83b79a9e4b7193ea0f0079353a2 251 SUPERFAMILY SSF51219 21 226 2.25E-42 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain LK06_RS22275 eed4f83b79a9e4b7193ea0f0079353a2 251 Pfam PF01987 Mitochondrial biogenesis AIM24 21 215 1.8E-29 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 06-07-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 328 2.8E-123 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 SUPERFAMILY SSF102741 355 433 8.5E-19 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 Gene3D G3DSA:3.40.50.300 160 344 5.6E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 Pfam PF09269 Domain of unknown function (DUF1967) 356 431 1.2E-23 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 Pfam PF01926 50S ribosome-binding GTPase 161 283 2.8E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 6.0E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 6.0E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 6.0E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 6.0E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 Gene3D G3DSA:2.70.210.12 3 156 1.1E-48 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 Pfam PF01018 GTP1/OBG 4 157 2.4E-52 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 SUPERFAMILY SSF82051 4 157 6.54E-47 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 Hamap MF_01454 GTPase Obg [obg]. 3 330 43.758 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 356 432 1.1E-26 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 LK06_RS09800 58fe48018ac8efa8edacfabb378e071d 481 SUPERFAMILY SSF52540 161 334 8.36E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29615 523c245713202ce70ad0aabdce1b2009 493 PIRSF PIRSF000538 6 472 2.3E-83 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LK06_RS29615 523c245713202ce70ad0aabdce1b2009 493 SUPERFAMILY SSF53067 8 248 6.69E-58 T 06-07-2017 LK06_RS29615 523c245713202ce70ad0aabdce1b2009 493 SUPERFAMILY SSF53067 249 458 1.84E-30 T 06-07-2017 LK06_RS29615 523c245713202ce70ad0aabdce1b2009 493 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 341 361 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LK06_RS29615 523c245713202ce70ad0aabdce1b2009 493 Gene3D G3DSA:3.30.420.40 5 246 1.7E-57 T 06-07-2017 LK06_RS29615 523c245713202ce70ad0aabdce1b2009 493 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 133 145 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LK06_RS29615 523c245713202ce70ad0aabdce1b2009 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 312 427 2.0E-14 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 LK06_RS29615 523c245713202ce70ad0aabdce1b2009 493 Gene3D G3DSA:3.30.420.40 249 427 5.8E-18 T 06-07-2017 LK06_RS29615 523c245713202ce70ad0aabdce1b2009 493 TIGRFAM TIGR01312 XylB: xylulokinase 10 462 7.4E-143 T 06-07-2017 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 LK06_RS29615 523c245713202ce70ad0aabdce1b2009 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 8 246 5.4E-76 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 LK06_RS02630 8cb522c4ab4c675f747281b2caba3c34 467 SUPERFAMILY SSF103473 241 445 1.13E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS02630 8cb522c4ab4c675f747281b2caba3c34 467 SUPERFAMILY SSF103473 2 186 1.13E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS02630 8cb522c4ab4c675f747281b2caba3c34 467 Pfam PF07690 Major Facilitator Superfamily 16 406 6.1E-43 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS02630 8cb522c4ab4c675f747281b2caba3c34 467 Gene3D G3DSA:1.20.1250.20 253 454 3.1E-13 T 06-07-2017 LK06_RS02630 8cb522c4ab4c675f747281b2caba3c34 467 Gene3D G3DSA:1.20.1250.20 3 186 4.7E-27 T 06-07-2017 LK06_RS02630 8cb522c4ab4c675f747281b2caba3c34 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 128 152 6.2E-6 T 06-07-2017 LK06_RS02630 8cb522c4ab4c675f747281b2caba3c34 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 98 118 6.2E-6 T 06-07-2017 LK06_RS02630 8cb522c4ab4c675f747281b2caba3c34 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 7 31 6.2E-6 T 06-07-2017 LK06_RS20585 0573dd51d697ae8a73685fb6625991e5 220 Gene3D G3DSA:1.10.1740.10 6 112 2.8E-26 T 06-07-2017 LK06_RS20585 0573dd51d697ae8a73685fb6625991e5 220 Pfam PF08281 Sigma-70, region 4 126 176 2.7E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20585 0573dd51d697ae8a73685fb6625991e5 220 Gene3D G3DSA:1.10.10.10 124 182 4.1E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20585 0573dd51d697ae8a73685fb6625991e5 220 SUPERFAMILY SSF88946 4 104 3.92E-25 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20585 0573dd51d697ae8a73685fb6625991e5 220 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 179 1.2E-19 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20585 0573dd51d697ae8a73685fb6625991e5 220 Pfam PF04542 Sigma-70 region 2 27 93 3.4E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20585 0573dd51d697ae8a73685fb6625991e5 220 SUPERFAMILY SSF88659 118 181 2.62E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS00935 08b9fce3c851b07338cc9b3a42386608 254 Gene3D G3DSA:3.40.366.10 12 242 4.6E-44 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS00935 08b9fce3c851b07338cc9b3a42386608 254 SUPERFAMILY SSF52151 12 240 1.02E-42 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS00935 08b9fce3c851b07338cc9b3a42386608 254 Pfam PF00698 Acyl transferase domain 14 138 1.2E-13 T 06-07-2017 IPR014043 Acyl transferase LK06_RS00935 08b9fce3c851b07338cc9b3a42386608 254 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 16 246 5.7E-14 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS15960 9c00ece4a007b01e6a067f3343892fce 227 Gene3D G3DSA:1.10.10.10 4 99 6.1E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15960 9c00ece4a007b01e6a067f3343892fce 227 SUPERFAMILY SSF46785 8 184 1.19E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15960 9c00ece4a007b01e6a067f3343892fce 227 Pfam PF03551 Transcriptional regulator PadR-like family 12 94 9.8E-15 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal LK06_RS23850 e2439db37092ba4a94bf2d87644860b5 260 Pfam PF12697 Alpha/beta hydrolase family 24 245 2.2E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS23850 e2439db37092ba4a94bf2d87644860b5 260 SUPERFAMILY SSF53474 4 259 5.74E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS23850 e2439db37092ba4a94bf2d87644860b5 260 Gene3D G3DSA:3.40.50.1820 3 258 1.2E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS17535 55c4db606ff1110a7ec6c68a2df17793 285 SUPERFAMILY SSF89392 44 264 7.85E-8 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX LK06_RS20125 6cc2ad51cfde3d081b154f47bc507b98 234 SUPERFAMILY SSF54427 100 230 2.93E-34 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS20125 6cc2ad51cfde3d081b154f47bc507b98 234 Gene3D G3DSA:3.10.450.50 100 230 3.3E-37 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS20125 6cc2ad51cfde3d081b154f47bc507b98 234 Pfam PF07366 SnoaL-like polyketide cyclase 102 227 2.8E-33 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 438 450 3.3E-21 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 3.3E-21 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 431 3.3E-21 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 292 306 3.3E-21 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 3.3E-21 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 TIGRFAM TIGR03356 BGL: beta-galactosidase 10 460 3.9E-178 T 06-07-2017 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 Pfam PF00232 Glycosyl hydrolase family 1 8 464 5.4E-156 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 372 380 - T 06-07-2017 IPR018120 Glycoside hydrolase family 1, active site LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 Gene3D G3DSA:3.20.20.80 9 468 4.9E-158 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 14 28 - T 06-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site LK06_RS10825 b3a1b0bea5bb6770b9a3d50b1cc9af7a 475 SUPERFAMILY SSF51445 9 468 7.57E-157 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS15635 92752cff24bd1bcf8c05bfb710f0cfb1 176 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 56 73 - T 06-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 LK06_RS15635 92752cff24bd1bcf8c05bfb710f0cfb1 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 128 2.7E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 LK06_RS15635 92752cff24bd1bcf8c05bfb710f0cfb1 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 61 73 2.7E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 LK06_RS15635 92752cff24bd1bcf8c05bfb710f0cfb1 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 101 116 2.7E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 LK06_RS15635 92752cff24bd1bcf8c05bfb710f0cfb1 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 2.7E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 LK06_RS15635 92752cff24bd1bcf8c05bfb710f0cfb1 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 129 144 2.7E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 LK06_RS15635 92752cff24bd1bcf8c05bfb710f0cfb1 176 PIRSF PIRSF001467 2 175 4.1E-56 T 06-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 LK06_RS15635 92752cff24bd1bcf8c05bfb710f0cfb1 176 SUPERFAMILY SSF50891 6 170 6.87E-63 T 06-07-2017 IPR029000 Cyclophilin-like domain LK06_RS15635 92752cff24bd1bcf8c05bfb710f0cfb1 176 Gene3D G3DSA:2.40.100.10 4 171 7.2E-63 T 06-07-2017 IPR029000 Cyclophilin-like domain LK06_RS15635 92752cff24bd1bcf8c05bfb710f0cfb1 176 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 169 2.2E-46 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 LK06_RS25665 232aa6670db5aceee43fd232757ef697 517 Gene3D G3DSA:3.40.50.980 168 321 4.8E-47 T 06-07-2017 LK06_RS25665 232aa6670db5aceee43fd232757ef697 517 Pfam PF00501 AMP-binding enzyme 12 409 1.9E-108 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS25665 232aa6670db5aceee43fd232757ef697 517 PRINTS PR00154 AMP-binding signature 157 168 9.1E-5 T 06-07-2017 IPR020459 AMP-binding LK06_RS25665 232aa6670db5aceee43fd232757ef697 517 PRINTS PR00154 AMP-binding signature 169 177 9.1E-5 T 06-07-2017 IPR020459 AMP-binding LK06_RS25665 232aa6670db5aceee43fd232757ef697 517 Gene3D G3DSA:3.40.50.980 8 167 2.7E-39 T 06-07-2017 LK06_RS25665 232aa6670db5aceee43fd232757ef697 517 Gene3D G3DSA:2.30.38.10 326 404 3.2E-25 T 06-07-2017 LK06_RS25665 232aa6670db5aceee43fd232757ef697 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS25665 232aa6670db5aceee43fd232757ef697 517 Gene3D G3DSA:3.30.300.30 405 506 1.5E-29 T 06-07-2017 LK06_RS25665 232aa6670db5aceee43fd232757ef697 517 SUPERFAMILY SSF56801 4 509 1.44E-153 T 06-07-2017 LK06_RS25665 232aa6670db5aceee43fd232757ef697 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 497 1.5E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 SUPERFAMILY SSF56112 236 425 5.06E-23 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 Gene3D G3DSA:1.10.510.10 312 439 3.4E-10 T 06-07-2017 LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 SMART SM00220 236 542 7.7E-5 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 Pfam PF00069 Protein kinase domain 247 440 1.0E-10 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 PRINTS PR01955 Frankia sp. LanC-like protein signature 808 828 1.8E-5 T 06-07-2017 IPR020434 LanC-like protein LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 PRINTS PR01955 Frankia sp. LanC-like protein signature 589 605 1.8E-5 T 06-07-2017 IPR020434 LanC-like protein LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 PRINTS PR01955 Frankia sp. LanC-like protein signature 865 882 1.8E-5 T 06-07-2017 IPR020434 LanC-like protein LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 PRINTS PR01955 Frankia sp. LanC-like protein signature 548 563 1.8E-5 T 06-07-2017 IPR020434 LanC-like protein LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 Gene3D G3DSA:3.30.200.20 235 311 2.1E-6 T 06-07-2017 LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 SMART SM01260 544 893 3.3E-4 T 06-07-2017 IPR007822 Lanthionine synthetase C-like LK06_RS01005 04dedebbc763f91eafeb778d3dbc30c5 906 SUPERFAMILY SSF158745 547 750 1.96E-13 T 06-07-2017 LK06_RS08115 a548f72e2762f9a7b05a5d9db1b08cf7 425 Pfam PF13416 Bacterial extracellular solute-binding protein 55 365 3.4E-49 T 06-07-2017 LK06_RS08115 a548f72e2762f9a7b05a5d9db1b08cf7 425 Gene3D G3DSA:3.40.190.10 37 150 1.8E-44 T 06-07-2017 LK06_RS08115 a548f72e2762f9a7b05a5d9db1b08cf7 425 Gene3D G3DSA:3.40.190.10 305 379 1.8E-44 T 06-07-2017 LK06_RS08115 a548f72e2762f9a7b05a5d9db1b08cf7 425 SUPERFAMILY SSF53850 36 413 2.17E-80 T 06-07-2017 LK06_RS08115 a548f72e2762f9a7b05a5d9db1b08cf7 425 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 145 162 - T 06-07-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 LK06_RS21320 b657d84c4b2ee3516f378d446cf0608a 196 SUPERFAMILY SSF46689 3 71 1.26E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS21320 b657d84c4b2ee3516f378d446cf0608a 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS21320 b657d84c4b2ee3516f378d446cf0608a 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS21320 b657d84c4b2ee3516f378d446cf0608a 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 9.0E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS21320 b657d84c4b2ee3516f378d446cf0608a 196 SUPERFAMILY SSF48498 80 186 2.91E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS21320 b657d84c4b2ee3516f378d446cf0608a 196 Gene3D G3DSA:1.10.10.60 3 42 5.5E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS21320 b657d84c4b2ee3516f378d446cf0608a 196 Gene3D G3DSA:1.10.357.10 60 177 7.6E-13 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS21320 b657d84c4b2ee3516f378d446cf0608a 196 Gene3D G3DSA:1.10.10.60 43 59 4.8E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS11355 09b56129d3f6a6d461798e17aea5ec62 493 SUPERFAMILY SSF103473 25 208 3.27E-35 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS11355 09b56129d3f6a6d461798e17aea5ec62 493 SUPERFAMILY SSF103473 262 480 3.27E-35 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS11355 09b56129d3f6a6d461798e17aea5ec62 493 Gene3D G3DSA:1.20.1250.20 282 485 1.3E-8 T 06-07-2017 LK06_RS11355 09b56129d3f6a6d461798e17aea5ec62 493 Gene3D G3DSA:1.20.1250.20 35 202 3.5E-20 T 06-07-2017 LK06_RS11355 09b56129d3f6a6d461798e17aea5ec62 493 Pfam PF07690 Major Facilitator Superfamily 36 420 9.7E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 9.3E-11 T 06-07-2017 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 9.3E-11 T 06-07-2017 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 9.3E-11 T 06-07-2017 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 9.3E-11 T 06-07-2017 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 319 3.4E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 Gene3D G3DSA:3.50.50.60 117 328 6.1E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 2.8E-12 T 06-07-2017 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 296 2.8E-12 T 06-07-2017 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 2.8E-12 T 06-07-2017 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 2.8E-12 T 06-07-2017 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 SUPERFAMILY SSF51905 14 191 1.52E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 Gene3D G3DSA:3.30.390.30 343 412 8.0E-18 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 Pfam PF14759 Reductase C-terminal 343 411 6.3E-9 T 06-07-2017 IPR028202 Reductase, C-terminal LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 Gene3D G3DSA:3.50.50.60 14 116 1.4E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 SUPERFAMILY SSF55424 335 414 1.51E-18 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 LK06_RS02900 454d0d7049eaeae38716315da5cc6280 463 SUPERFAMILY SSF51905 153 330 1.73E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20495 3c91dc57a188a74ae38352ba180afa06 194 Gene3D G3DSA:3.90.1140.10 8 175 3.6E-24 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase LK06_RS20495 3c91dc57a188a74ae38352ba180afa06 194 Pfam PF13563 2'-5' RNA ligase superfamily 13 158 6.6E-23 T 06-07-2017 LK06_RS20495 3c91dc57a188a74ae38352ba180afa06 194 SUPERFAMILY SSF55144 6 174 2.12E-30 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 Gene3D G3DSA:1.20.5.100 213 238 1.0E-15 T 06-07-2017 LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 328 429 2.2E-24 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 190 1.5E-55 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 Gene3D G3DSA:3.40.50.720 4 212 8.0E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 SUPERFAMILY SSF48179 210 306 5.95E-26 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 SUPERFAMILY SSF52413 320 439 4.71E-32 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 Gene3D G3DSA:3.40.50.720 240 445 1.6E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 425 4.8E-122 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 SMART SM00984 328 429 1.3E-41 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 PIRSF PIRSF000124 3 444 5.3E-113 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 302 1.0E-29 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 SUPERFAMILY SSF51735 4 197 2.16E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11990 6d4d3c99dd7fb434accec72dc5fc75d4 447 PIRSF PIRSF500134 3 447 2.1E-150 T 06-07-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 LK06_RS21060 0413de5304d9b1e461be93ae17c4480f 310 Gene3D G3DSA:3.40.50.300 3 227 2.5E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21060 0413de5304d9b1e461be93ae17c4480f 310 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS21060 0413de5304d9b1e461be93ae17c4480f 310 Pfam PF00005 ABC transporter 20 163 2.2E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS21060 0413de5304d9b1e461be93ae17c4480f 310 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 306 1.2E-99 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 LK06_RS21060 0413de5304d9b1e461be93ae17c4480f 310 SUPERFAMILY SSF52540 4 226 4.71E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21060 0413de5304d9b1e461be93ae17c4480f 310 SMART SM00382 29 236 7.2E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS24035 cd7b9ae8d7f8b600b3b72f9a6a6f97ed 240 Pfam PF00699 Urease beta subunit 119 201 1.2E-29 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24035 cd7b9ae8d7f8b600b3b72f9a6a6f97ed 240 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 121 204 2.7E-27 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24035 cd7b9ae8d7f8b600b3b72f9a6a6f97ed 240 Pfam PF00547 Urease, gamma subunit 2 99 1.4E-34 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24035 cd7b9ae8d7f8b600b3b72f9a6a6f97ed 240 Gene3D G3DSA:3.30.280.10 2 99 2.6E-35 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24035 cd7b9ae8d7f8b600b3b72f9a6a6f97ed 240 Gene3D G3DSA:2.10.150.10 108 226 1.7E-37 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24035 cd7b9ae8d7f8b600b3b72f9a6a6f97ed 240 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 31 99 8.0E-26 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24035 cd7b9ae8d7f8b600b3b72f9a6a6f97ed 240 SUPERFAMILY SSF54111 2 101 2.75E-31 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24035 cd7b9ae8d7f8b600b3b72f9a6a6f97ed 240 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 2 99 5.5E-30 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS24035 cd7b9ae8d7f8b600b3b72f9a6a6f97ed 240 SUPERFAMILY SSF51278 108 226 2.62E-37 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS05400 46e5497196f58bcca18a612a25c3c646 398 Pfam PF02515 CoA-transferase family III 8 374 8.4E-109 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 LK06_RS05400 46e5497196f58bcca18a612a25c3c646 398 Gene3D G3DSA:3.30.1540.10 223 306 3.7E-28 T 06-07-2017 LK06_RS05400 46e5497196f58bcca18a612a25c3c646 398 SUPERFAMILY SSF89796 5 397 3.01E-119 T 06-07-2017 IPR023606 CoA-transferase family III domain LK06_RS05400 46e5497196f58bcca18a612a25c3c646 398 Gene3D G3DSA:3.40.50.10540 6 217 8.8E-95 T 06-07-2017 IPR023606 CoA-transferase family III domain LK06_RS05400 46e5497196f58bcca18a612a25c3c646 398 Gene3D G3DSA:3.40.50.10540 307 397 8.8E-95 T 06-07-2017 IPR023606 CoA-transferase family III domain LK06_RS08470 521c3f3dcfca13a259fc139a5cf86093 398 Gene3D G3DSA:3.40.47.10 208 229 1.4E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08470 521c3f3dcfca13a259fc139a5cf86093 398 Gene3D G3DSA:3.40.47.10 22 116 1.4E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08470 521c3f3dcfca13a259fc139a5cf86093 398 Pfam PF02803 Thiolase, C-terminal domain 273 376 2.7E-12 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 LK06_RS08470 521c3f3dcfca13a259fc139a5cf86093 398 Pfam PF00108 Thiolase, N-terminal domain 5 192 9.5E-18 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 LK06_RS08470 521c3f3dcfca13a259fc139a5cf86093 398 ProSitePatterns PS00737 Thiolases signature 2. 334 350 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 LK06_RS08470 521c3f3dcfca13a259fc139a5cf86093 398 Gene3D G3DSA:3.40.47.10 254 390 2.2E-30 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08470 521c3f3dcfca13a259fc139a5cf86093 398 Gene3D G3DSA:3.40.47.10 151 189 2.2E-30 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08470 521c3f3dcfca13a259fc139a5cf86093 398 SUPERFAMILY SSF53901 4 116 1.29E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08470 521c3f3dcfca13a259fc139a5cf86093 398 SUPERFAMILY SSF53901 187 394 1.29E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08470 521c3f3dcfca13a259fc139a5cf86093 398 PIRSF PIRSF000429 1 394 4.9E-65 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 SMART SM00304 157 216 4.3E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 SMART SM00387 313 414 4.7E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 SMART SM00388 217 275 7.8E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 SUPERFAMILY SSF47384 201 275 3.34E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 Gene3D G3DSA:1.10.287.130 208 262 1.5E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 Pfam PF00672 HAMP domain 138 212 4.8E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 275 2.2E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 411 4.2E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 Gene3D G3DSA:3.30.565.10 263 412 1.4E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 SUPERFAMILY SSF55874 264 412 6.16E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22770 b61a9a2ba332b2ea3414233bd4da1095 416 SUPERFAMILY SSF158472 158 213 5.89E-5 T 06-07-2017 LK06_RS00825 dab33ae48d7ca6e20c0b701ef5142a92 612 SUPERFAMILY SSF48208 212 611 6.05E-109 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS00825 dab33ae48d7ca6e20c0b701ef5142a92 612 Pfam PF00723 Glycosyl hydrolases family 15 238 554 1.5E-53 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 LK06_RS00825 dab33ae48d7ca6e20c0b701ef5142a92 612 Gene3D G3DSA:1.50.10.10 232 611 5.6E-102 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 LK06_RS31445 cc9f822802b405022db45ede3f2bb63f 333 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 260 1.5E-44 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS31445 cc9f822802b405022db45ede3f2bb63f 333 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 1.1E-5 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 LK06_RS31445 cc9f822802b405022db45ede3f2bb63f 333 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 1.1E-5 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 LK06_RS31445 cc9f822802b405022db45ede3f2bb63f 333 PRINTS PR01713 Nucleotide sugar epimerase signature 231 246 1.1E-5 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 LK06_RS31445 cc9f822802b405022db45ede3f2bb63f 333 Gene3D G3DSA:3.40.50.720 1 117 9.6E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31445 cc9f822802b405022db45ede3f2bb63f 333 Gene3D G3DSA:3.40.50.720 150 325 9.6E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31445 cc9f822802b405022db45ede3f2bb63f 333 SUPERFAMILY SSF51735 145 327 5.63E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31445 cc9f822802b405022db45ede3f2bb63f 333 SUPERFAMILY SSF51735 1 108 5.63E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS17375 0be31c1dd72d14911c9834f89bc2f69d 470 Gene3D G3DSA:3.40.50.300 70 157 4.0E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17375 0be31c1dd72d14911c9834f89bc2f69d 470 Gene3D G3DSA:3.40.50.300 251 375 4.0E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17375 0be31c1dd72d14911c9834f89bc2f69d 470 Pfam PF12846 AAA-like domain 69 350 3.2E-14 T 06-07-2017 LK06_RS17375 0be31c1dd72d14911c9834f89bc2f69d 470 SUPERFAMILY SSF52540 39 424 1.37E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12675 00924654d38e6e0c4dfcb64cea96199c 200 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 28 164 2.6E-66 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12675 00924654d38e6e0c4dfcb64cea96199c 200 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 17 163 40.01 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12675 00924654d38e6e0c4dfcb64cea96199c 200 SUPERFAMILY SSF56770 28 167 2.88E-61 T 06-07-2017 LK06_RS12675 00924654d38e6e0c4dfcb64cea96199c 200 Gene3D G3DSA:3.40.50.700 32 164 1.4E-36 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12675 00924654d38e6e0c4dfcb64cea96199c 200 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 49 158 6.3E-24 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 Pfam PF05345 Putative Ig domain 587 627 1.3E-10 T 06-07-2017 IPR008009 Putative Ig LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 Gene3D G3DSA:1.10.390.10 373 545 1.5E-50 T 06-07-2017 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 221 368 2.2E-48 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 79 115 4.2E-13 T 06-07-2017 IPR011096 FTP domain LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 371 545 1.1E-52 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 359 375 2.7E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 323 343 2.7E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 380 391 2.7E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 447 463 2.7E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 SUPERFAMILY SSF49313 557 640 7.06E-13 T 06-07-2017 IPR015919 Cadherin-like GO:0005509|GO:0016020 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 Gene3D G3DSA:2.60.40.10 557 639 4.6E-10 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 Gene3D G3DSA:3.10.170.10 221 372 1.5E-46 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 SUPERFAMILY SSF55486 220 545 1.83E-82 T 06-07-2017 LK06_RS31060 42da04c144a7c0aa1227f9ebe4ae195a 795 SUPERFAMILY SSF49785 650 790 1.87E-5 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS22675 728a5fc03a57a47d1fefb823efc7202c 269 Gene3D G3DSA:1.20.1540.10 135 255 4.9E-4 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 LK06_RS27860 bbd03cbac4b50b73d7a4f424ff2db64a 467 SUPERFAMILY SSF51556 60 388 2.88E-105 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS27860 bbd03cbac4b50b73d7a4f424ff2db64a 467 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 6 459 1.4E-169 T 06-07-2017 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 LK06_RS27860 bbd03cbac4b50b73d7a4f424ff2db64a 467 Gene3D G3DSA:2.30.40.10 383 457 1.3E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS27860 bbd03cbac4b50b73d7a4f424ff2db64a 467 Gene3D G3DSA:3.20.20.140 75 382 4.5E-115 T 06-07-2017 LK06_RS27860 bbd03cbac4b50b73d7a4f424ff2db64a 467 Gene3D G3DSA:2.30.40.10 4 74 5.9E-30 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS27860 bbd03cbac4b50b73d7a4f424ff2db64a 467 Pfam PF01979 Amidohydrolase family 56 441 7.2E-23 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS27860 bbd03cbac4b50b73d7a4f424ff2db64a 467 SUPERFAMILY SSF51338 4 59 3.42E-32 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS27860 bbd03cbac4b50b73d7a4f424ff2db64a 467 SUPERFAMILY SSF51338 388 458 3.42E-32 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS20190 f59030a74d3c034a80966a2630fc57c4 895 Gene3D G3DSA:1.10.510.10 478 586 1.4E-22 T 06-07-2017 LK06_RS20190 f59030a74d3c034a80966a2630fc57c4 895 Gene3D G3DSA:1.10.510.10 103 196 1.4E-22 T 06-07-2017 LK06_RS20190 f59030a74d3c034a80966a2630fc57c4 895 SMART SM00220 23 585 6.8E-8 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20190 f59030a74d3c034a80966a2630fc57c4 895 SUPERFAMILY SSF56112 93 189 4.19E-21 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS20190 f59030a74d3c034a80966a2630fc57c4 895 SUPERFAMILY SSF56112 479 609 4.19E-21 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS20190 f59030a74d3c034a80966a2630fc57c4 895 Pfam PF00069 Protein kinase domain 100 186 7.1E-7 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS30005 81c24a8e078a839e1c92b5985ccd387d 232 SUPERFAMILY SSF46689 10 78 2.48E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS30005 81c24a8e078a839e1c92b5985ccd387d 232 Gene3D G3DSA:1.10.357.10 5 217 1.1E-40 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS30005 81c24a8e078a839e1c92b5985ccd387d 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 1.5E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30005 81c24a8e078a839e1c92b5985ccd387d 232 SUPERFAMILY SSF48498 92 223 1.33E-29 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS02740 3e539f55936096f541d262825dc684d7 185 Gene3D G3DSA:1.10.1200.10 118 181 3.2E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02740 3e539f55936096f541d262825dc684d7 185 SUPERFAMILY SSF56801 13 124 7.59E-16 T 06-07-2017 LK06_RS02740 3e539f55936096f541d262825dc684d7 185 SMART SM00823 Phosphopantetheine attachment site 113 182 8.2E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS02740 3e539f55936096f541d262825dc684d7 185 SUPERFAMILY SSF47336 106 178 8.24E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02740 3e539f55936096f541d262825dc684d7 185 Gene3D G3DSA:3.30.300.30 13 117 6.9E-17 T 06-07-2017 LK06_RS02740 3e539f55936096f541d262825dc684d7 185 Pfam PF00550 Phosphopantetheine attachment site 115 174 7.5E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02740 3e539f55936096f541d262825dc684d7 185 Pfam PF13193 AMP-binding enzyme C-terminal domain 15 83 7.6E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 SUPERFAMILY SSF51735 5 251 6.2E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 Gene3D G3DSA:3.40.50.720 1 251 9.8E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 6.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 6.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 6.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 6.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 6.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 2.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 2.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS18975 1db3903fad37e9dbdd7d8ed5ff18bee2 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 1.6E-66 T 06-07-2017 LK06_RS13705 c6af37505b8816d85aebf1ba1e751c76 333 Pfam PF02569 Pantoate-beta-alanine ligase 19 322 9.2E-90 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 LK06_RS13705 c6af37505b8816d85aebf1ba1e751c76 333 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 20 322 8.2E-79 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 LK06_RS13705 c6af37505b8816d85aebf1ba1e751c76 333 Gene3D G3DSA:3.30.1300.10 176 220 9.2E-35 T 06-07-2017 LK06_RS13705 c6af37505b8816d85aebf1ba1e751c76 333 Gene3D G3DSA:3.30.1300.10 267 327 9.2E-35 T 06-07-2017 LK06_RS13705 c6af37505b8816d85aebf1ba1e751c76 333 Hamap MF_00158 Pantothenate synthetase [panC]. 4 324 38.893 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 LK06_RS13705 c6af37505b8816d85aebf1ba1e751c76 333 Gene3D G3DSA:3.40.50.620 15 175 9.0E-70 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS13705 c6af37505b8816d85aebf1ba1e751c76 333 SUPERFAMILY SSF52374 14 224 1.41E-83 T 06-07-2017 LK06_RS13705 c6af37505b8816d85aebf1ba1e751c76 333 SUPERFAMILY SSF52374 273 326 9.19E-6 T 06-07-2017 LK06_RS09860 9ec9b810354e7e2d011887b0d55a6ba5 753 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 246 7.0E-41 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 LK06_RS09860 9ec9b810354e7e2d011887b0d55a6ba5 753 SUPERFAMILY SSF56519 53 261 7.98E-38 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 LK06_RS09860 9ec9b810354e7e2d011887b0d55a6ba5 753 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 16 662 2.2E-172 T 06-07-2017 IPR017790 Penicillin-binding protein 2 GO:0016020 LK06_RS09860 9ec9b810354e7e2d011887b0d55a6ba5 753 SUPERFAMILY SSF56601 213 460 1.13E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS09860 9ec9b810354e7e2d011887b0d55a6ba5 753 SUPERFAMILY SSF56601 517 664 1.13E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS09860 9ec9b810354e7e2d011887b0d55a6ba5 753 Pfam PF00905 Penicillin binding protein transpeptidase domain 298 658 5.8E-76 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS09860 9ec9b810354e7e2d011887b0d55a6ba5 753 Gene3D G3DSA:3.90.1310.10 137 259 9.5E-32 T 06-07-2017 LK06_RS09860 9ec9b810354e7e2d011887b0d55a6ba5 753 Gene3D G3DSA:3.40.710.10 261 474 4.5E-85 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS09860 9ec9b810354e7e2d011887b0d55a6ba5 753 Gene3D G3DSA:3.40.710.10 512 663 4.5E-85 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS01055 61030bf84ac5c524afab3b06adf4ea43 322 SUPERFAMILY SSF103481 43 123 3.66E-6 T 06-07-2017 LK06_RS17040 0f7ff8ba09dac73bce1b5424f2cbb9bd 509 SUPERFAMILY SSF56235 23 287 3.43E-64 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS17040 0f7ff8ba09dac73bce1b5424f2cbb9bd 509 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 476 46.343 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 LK06_RS17040 0f7ff8ba09dac73bce1b5424f2cbb9bd 509 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 475 5.6E-156 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 LK06_RS17040 0f7ff8ba09dac73bce1b5424f2cbb9bd 509 Pfam PF00156 Phosphoribosyl transferase domain 301 404 4.3E-7 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 LK06_RS17040 0f7ff8ba09dac73bce1b5424f2cbb9bd 509 Gene3D G3DSA:3.60.20.10 23 275 9.6E-67 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS17040 0f7ff8ba09dac73bce1b5424f2cbb9bd 509 PIRSF PIRSF000485 19 486 1.3E-159 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 LK06_RS17040 0f7ff8ba09dac73bce1b5424f2cbb9bd 509 Pfam PF13522 Glutamine amidotransferase domain 85 228 2.2E-15 T 06-07-2017 LK06_RS17040 0f7ff8ba09dac73bce1b5424f2cbb9bd 509 Gene3D G3DSA:3.40.50.2020 291 457 1.7E-43 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS17040 0f7ff8ba09dac73bce1b5424f2cbb9bd 509 SUPERFAMILY SSF53271 269 483 1.26E-67 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS21595 4cc3b1990b143df9dbcec0ea0ac83898 189 SUPERFAMILY SSF56349 1 165 1.91E-34 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS21595 4cc3b1990b143df9dbcec0ea0ac83898 189 Gene3D G3DSA:1.10.443.10 1 165 2.1E-39 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS21595 4cc3b1990b143df9dbcec0ea0ac83898 189 Pfam PF00589 Phage integrase family 4 158 2.1E-22 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 198 2.4E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 1.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 1.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 1.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 SMART SM00448 5 118 8.1E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 Gene3D G3DSA:1.10.10.10 147 204 3.5E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 Gene3D G3DSA:3.40.50.2300 2 146 3.7E-38 T 06-07-2017 LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 Pfam PF00072 Response regulator receiver domain 7 119 1.2E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 SUPERFAMILY SSF52172 4 132 2.7E-30 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 SUPERFAMILY SSF46894 127 204 5.1E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS21950 1c0d8755396040d1c2986834ba751777 204 SMART SM00421 141 198 2.3E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS18150 2cc47f433cd3beba10d7fab7fc159c9c 436 SUPERFAMILY SSF55874 316 428 6.66E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS18150 2cc47f433cd3beba10d7fab7fc159c9c 436 Pfam PF07730 Histidine kinase 223 288 5.6E-18 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS18150 2cc47f433cd3beba10d7fab7fc159c9c 436 SMART SM00387 334 430 0.0015 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS18150 2cc47f433cd3beba10d7fab7fc159c9c 436 Gene3D G3DSA:3.30.565.10 332 429 2.2E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS30915 ceca7a7ef172f3c7238f08ff1067615e 481 SUPERFAMILY SSF55486 259 478 5.27E-46 T 06-07-2017 LK06_RS30915 ceca7a7ef172f3c7238f08ff1067615e 481 Gene3D G3DSA:1.10.390.10 345 478 5.0E-21 T 06-07-2017 LK06_RS30915 ceca7a7ef172f3c7238f08ff1067615e 481 Pfam PF01433 Peptidase family M1 330 383 1.9E-16 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS30915 ceca7a7ef172f3c7238f08ff1067615e 481 Pfam PF01433 Peptidase family M1 71 298 2.9E-19 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS30915 ceca7a7ef172f3c7238f08ff1067615e 481 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 331 346 1.5E-9 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS30915 ceca7a7ef172f3c7238f08ff1067615e 481 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 185 200 1.5E-9 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS30915 ceca7a7ef172f3c7238f08ff1067615e 481 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 232 247 1.5E-9 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS30915 ceca7a7ef172f3c7238f08ff1067615e 481 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 350 362 1.5E-9 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS30915 ceca7a7ef172f3c7238f08ff1067615e 481 SUPERFAMILY SSF63737 56 248 3.01E-37 T 06-07-2017 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 SUPERFAMILY SSF46977 446 584 7.06E-52 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 584 2.7E-279 T 06-07-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 Gene3D G3DSA:4.10.80.40 543 580 3.6E-18 T 06-07-2017 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 Gene3D G3DSA:1.20.58.100 426 542 8.3E-43 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 2.4E-5 T 06-07-2017 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.4E-5 T 06-07-2017 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 Gene3D G3DSA:3.90.700.10 243 349 2.5E-41 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 06-07-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 SUPERFAMILY SSF56425 236 354 1.03E-42 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 Gene3D G3DSA:3.50.50.60 350 420 8.4E-113 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 Gene3D G3DSA:3.50.50.60 2 242 8.4E-113 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 SUPERFAMILY SSF51905 358 439 5.68E-71 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 SUPERFAMILY SSF51905 2 259 5.68E-71 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.2E-5 T 06-07-2017 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 1.2E-5 T 06-07-2017 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 Pfam PF00890 FAD binding domain 7 400 4.5E-113 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 584 3.4E-46 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 PIRSF PIRSF000171 1 578 4.2E-50 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20540 d4af2241bd1eb17ab51120d6fda5c3b8 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 584 1.3E-247 T 06-07-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS12915 2211ba71725e9ef28c8554b3d75bc2f0 219 Pfam PF12838 4Fe-4S dicluster domain 64 124 5.2E-11 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LK06_RS12915 2211ba71725e9ef28c8554b3d75bc2f0 219 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 21 148 4.4E-44 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12915 2211ba71725e9ef28c8554b3d75bc2f0 219 Gene3D G3DSA:1.10.1060.10 20 134 3.0E-19 T 06-07-2017 LK06_RS12915 2211ba71725e9ef28c8554b3d75bc2f0 219 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS12915 2211ba71725e9ef28c8554b3d75bc2f0 219 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS12915 2211ba71725e9ef28c8554b3d75bc2f0 219 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 12 154 28.426 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12915 2211ba71725e9ef28c8554b3d75bc2f0 219 SUPERFAMILY SSF54862 38 155 3.14E-27 T 06-07-2017 LK06_RS28580 5ceb6b57f6d7c0a50756aaba2d08f096 545 SUPERFAMILY SSF52540 17 219 1.86E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28580 5ceb6b57f6d7c0a50756aaba2d08f096 545 SMART SM00382 361 535 7.7E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS28580 5ceb6b57f6d7c0a50756aaba2d08f096 545 SMART SM00382 29 214 3.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS28580 5ceb6b57f6d7c0a50756aaba2d08f096 545 Pfam PF00005 ABC transporter 32 170 8.4E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS28580 5ceb6b57f6d7c0a50756aaba2d08f096 545 Pfam PF00005 ABC transporter 357 482 3.3E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS28580 5ceb6b57f6d7c0a50756aaba2d08f096 545 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS28580 5ceb6b57f6d7c0a50756aaba2d08f096 545 SUPERFAMILY SSF52540 317 534 2.45E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28580 5ceb6b57f6d7c0a50756aaba2d08f096 545 Gene3D G3DSA:3.40.50.300 356 534 3.3E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28580 5ceb6b57f6d7c0a50756aaba2d08f096 545 Gene3D G3DSA:3.40.50.300 9 249 7.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26250 6cbdc9ad8561647f18127c59e85f78be 285 Gene3D G3DSA:3.40.50.150 58 199 9.4E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26250 6cbdc9ad8561647f18127c59e85f78be 285 Pfam PF04072 Leucine carboxyl methyltransferase 13 188 8.3E-42 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 LK06_RS26250 6cbdc9ad8561647f18127c59e85f78be 285 SUPERFAMILY SSF53335 9 275 4.62E-58 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26250 6cbdc9ad8561647f18127c59e85f78be 285 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 265 1.6E-44 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 LK06_RS10730 c9a6bf908d3debcfa8708d257afa7f71 386 SUPERFAMILY SSF47203 232 382 5.32E-52 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS10730 c9a6bf908d3debcfa8708d257afa7f71 386 SUPERFAMILY SSF56645 2 247 2.49E-81 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS10730 c9a6bf908d3debcfa8708d257afa7f71 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 6.2E-37 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS10730 c9a6bf908d3debcfa8708d257afa7f71 386 Gene3D G3DSA:1.10.540.10 1 119 8.6E-42 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS10730 c9a6bf908d3debcfa8708d257afa7f71 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS10730 c9a6bf908d3debcfa8708d257afa7f71 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 1.2E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS10730 c9a6bf908d3debcfa8708d257afa7f71 386 Gene3D G3DSA:1.20.140.10 226 382 6.1E-66 T 06-07-2017 LK06_RS10730 c9a6bf908d3debcfa8708d257afa7f71 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS10730 c9a6bf908d3debcfa8708d257afa7f71 386 Gene3D G3DSA:2.40.110.10 121 225 8.2E-37 T 06-07-2017 LK06_RS10730 c9a6bf908d3debcfa8708d257afa7f71 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 222 9.0E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS04755 c047b70c0b7c3eacbf153d8a0ed0e352 66 SUPERFAMILY SSF50118 1 65 4.9E-22 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor LK06_RS04755 c047b70c0b7c3eacbf153d8a0ed0e352 66 Pfam PF08940 Domain of unknown function (DUF1918) 1 57 1.0E-25 T 06-07-2017 IPR015035 Domain of unknown function DUF1918 LK06_RS19025 40894eed496a890f75e69a944a158dcc 370 Pfam PF03747 ADP-ribosylglycohydrolase 23 325 7.5E-50 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 LK06_RS19025 40894eed496a890f75e69a944a158dcc 370 SUPERFAMILY SSF101478 159 346 2.75E-54 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 LK06_RS19025 40894eed496a890f75e69a944a158dcc 370 SUPERFAMILY SSF101478 16 131 2.75E-54 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 LK06_RS21215 9ac9790422c3ec54bf9538fd44b82d34 253 Pfam PF01614 Bacterial transcriptional regulator 117 241 3.8E-30 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal LK06_RS21215 9ac9790422c3ec54bf9538fd44b82d34 253 Gene3D G3DSA:3.30.450.40 71 246 5.2E-58 T 06-07-2017 IPR029016 GAF domain-like LK06_RS21215 9ac9790422c3ec54bf9538fd44b82d34 253 SUPERFAMILY SSF46785 3 72 1.37E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21215 9ac9790422c3ec54bf9538fd44b82d34 253 SUPERFAMILY SSF55781 57 243 1.5E-49 T 06-07-2017 IPR029016 GAF domain-like LK06_RS21215 9ac9790422c3ec54bf9538fd44b82d34 253 Pfam PF09339 IclR helix-turn-helix domain 4 52 1.3E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS21215 9ac9790422c3ec54bf9538fd44b82d34 253 SMART SM00346 2 89 2.2E-26 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS21215 9ac9790422c3ec54bf9538fd44b82d34 253 Gene3D G3DSA:1.10.10.10 3 70 1.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21645 3f2ba4d5f3b7b7f21d47e9110b99b89a 178 ProSitePatterns PS00893 Nudix box signature. 68 89 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS21645 3f2ba4d5f3b7b7f21d47e9110b99b89a 178 PRINTS PR00502 NUDIX hydrolase family signature 63 77 6.9E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS21645 3f2ba4d5f3b7b7f21d47e9110b99b89a 178 PRINTS PR00502 NUDIX hydrolase family signature 77 92 6.9E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS21645 3f2ba4d5f3b7b7f21d47e9110b99b89a 178 Gene3D G3DSA:3.90.79.10 34 159 1.9E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS21645 3f2ba4d5f3b7b7f21d47e9110b99b89a 178 SUPERFAMILY SSF55811 31 166 1.49E-26 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS21645 3f2ba4d5f3b7b7f21d47e9110b99b89a 178 Pfam PF00293 NUDIX domain 34 159 1.2E-20 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS30185 d65107f344e35eda62ed269560f46488 579 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 489 535 2.8E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS30185 d65107f344e35eda62ed269560f46488 579 Gene3D G3DSA:3.30.450.40 205 367 1.6E-21 T 06-07-2017 IPR029016 GAF domain-like LK06_RS30185 d65107f344e35eda62ed269560f46488 579 SMART SM00065 55 203 9.7E-20 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS30185 d65107f344e35eda62ed269560f46488 579 SMART SM00065 224 371 3.7E-5 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS30185 d65107f344e35eda62ed269560f46488 579 Pfam PF07730 Histidine kinase 379 442 8.3E-10 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS30185 d65107f344e35eda62ed269560f46488 579 Gene3D G3DSA:3.30.565.10 481 571 6.0E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS30185 d65107f344e35eda62ed269560f46488 579 SUPERFAMILY SSF55874 452 570 3.14E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS30185 d65107f344e35eda62ed269560f46488 579 SMART SM00387 482 572 6.2E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS30185 d65107f344e35eda62ed269560f46488 579 Pfam PF13185 GAF domain 226 362 7.1E-11 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS30185 d65107f344e35eda62ed269560f46488 579 Pfam PF13185 GAF domain 54 194 1.4E-18 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS30185 d65107f344e35eda62ed269560f46488 579 Gene3D G3DSA:3.30.450.40 44 201 1.2E-34 T 06-07-2017 IPR029016 GAF domain-like LK06_RS30185 d65107f344e35eda62ed269560f46488 579 SUPERFAMILY SSF55781 37 221 3.71E-42 T 06-07-2017 IPR029016 GAF domain-like LK06_RS30185 d65107f344e35eda62ed269560f46488 579 SUPERFAMILY SSF55781 206 388 2.84E-23 T 06-07-2017 IPR029016 GAF domain-like LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 Pfam PF00035 Double-stranded RNA binding motif 181 244 4.1E-17 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 SUPERFAMILY SSF54768 135 246 2.2E-26 T 06-07-2017 LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 33 245 2.7E-72 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 ProSitePatterns PS00517 Ribonuclease III family signature. 63 71 - T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 Hamap MF_00104 Ribonuclease 3 [rnc]. 30 243 30.509 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 SMART SM00535 41 174 2.2E-62 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 SUPERFAMILY SSF69065 26 183 1.13E-49 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 Pfam PF14622 Ribonuclease-III-like 40 165 2.2E-38 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 SMART SM00358 181 247 6.9E-24 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 Gene3D G3DSA:1.10.1520.10 30 171 2.4E-47 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 LK06_RS24295 0c0f3d224be036e1dd7fef329681ed56 270 Gene3D G3DSA:3.30.160.20 179 246 2.5E-25 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain LK06_RS14405 79ca69aaf2653c2099ca6225c94c2242 123 SUPERFAMILY SSF52821 8 115 2.1E-32 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14405 79ca69aaf2653c2099ca6225c94c2242 123 SMART SM00450 14 111 1.3E-24 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14405 79ca69aaf2653c2099ca6225c94c2242 123 Gene3D G3DSA:3.40.250.10 6 113 6.8E-30 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14405 79ca69aaf2653c2099ca6225c94c2242 123 Pfam PF00581 Rhodanese-like domain 17 107 5.8E-14 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 Gene3D G3DSA:3.90.780.10 383 599 7.2E-45 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 SUPERFAMILY SSF56300 46 381 5.48E-76 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 SUPERFAMILY SSF55816 380 591 2.62E-44 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 7 35 6.1E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 Gene3D G3DSA:3.60.21.10 47 381 1.8E-79 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 Pfam PF02872 5'-nucleotidase, C-terminal domain 383 561 7.7E-33 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 PRINTS PR01607 Apyrase family signature 536 555 1.9E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 PRINTS PR01607 Apyrase family signature 285 308 1.9E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 PRINTS PR01607 Apyrase family signature 445 468 1.9E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 PRINTS PR01607 Apyrase family signature 50 68 1.9E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 PRINTS PR01607 Apyrase family signature 318 338 1.9E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 PRINTS PR01607 Apyrase family signature 252 269 1.9E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 Pfam PF00149 Calcineurin-like phosphoesterase 52 302 1.1E-9 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 LK06_RS14540 93b03389a77e83e88d6bbf01fd26e2f5 608 ProSitePatterns PS00786 5'-nucleotidase signature 2. 150 161 - T 06-07-2017 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-73621|Reactome: R-HSA-74259 LK06_RS16855 43a6a1ff3b99c6a2e36af1fd0c33caef 249 Pfam PF04555 Restriction endonuclease XhoI 30 208 4.7E-52 T 06-07-2017 IPR007636 Restriction endonuclease, type II, XhoI GO:0003677|GO:0009036|GO:0009307 LK06_RS00720 e9b8dc1b97b55a8803c1f8492dbc11b3 191 Gene3D G3DSA:3.40.50.1950 8 154 2.4E-14 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS00720 e9b8dc1b97b55a8803c1f8492dbc11b3 191 SUPERFAMILY SSF52507 13 157 8.5E-18 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS00720 e9b8dc1b97b55a8803c1f8492dbc11b3 191 Pfam PF02441 Flavoprotein 23 130 7.1E-6 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS23475 4c037263e8248b03f55fed285a658b50 250 SUPERFAMILY SSF55961 4 151 7.7E-8 T 06-07-2017 LK06_RS29695 68b317c5f4fda0c111bd8a32502ae6c2 149 SMART SM00347 29 130 4.2E-21 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29695 68b317c5f4fda0c111bd8a32502ae6c2 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 1.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29695 68b317c5f4fda0c111bd8a32502ae6c2 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 1.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29695 68b317c5f4fda0c111bd8a32502ae6c2 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 1.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29695 68b317c5f4fda0c111bd8a32502ae6c2 149 SUPERFAMILY SSF46785 7 142 2.17E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29695 68b317c5f4fda0c111bd8a32502ae6c2 149 Pfam PF12802 MarR family 34 93 3.7E-11 T 06-07-2017 LK06_RS29695 68b317c5f4fda0c111bd8a32502ae6c2 149 Gene3D G3DSA:1.10.10.10 3 142 5.4E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13780 e03e663e07c49921e5e00d829c5c54bc 119 TIGRFAM TIGR00526 folB_dom: FolB domain 2 118 5.3E-31 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LK06_RS13780 e03e663e07c49921e5e00d829c5c54bc 119 SUPERFAMILY SSF55620 2 118 6.12E-37 T 06-07-2017 LK06_RS13780 e03e663e07c49921e5e00d829c5c54bc 119 Pfam PF02152 Dihydroneopterin aldolase 5 115 6.7E-36 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LK06_RS13780 e03e663e07c49921e5e00d829c5c54bc 119 SMART SM00905 4 116 2.3E-49 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LK06_RS13780 e03e663e07c49921e5e00d829c5c54bc 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 116 1.5E-34 T 06-07-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LK06_RS13780 e03e663e07c49921e5e00d829c5c54bc 119 Gene3D G3DSA:3.30.1130.10 2 118 8.2E-46 T 06-07-2017 LK06_RS13635 28f8e3f953c6cf563a8e78c80edbc800 199 SUPERFAMILY SSF46689 7 84 5.13E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS13635 28f8e3f953c6cf563a8e78c80edbc800 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS13635 28f8e3f953c6cf563a8e78c80edbc800 199 Gene3D G3DSA:1.10.357.10 5 191 6.0E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS13635 28f8e3f953c6cf563a8e78c80edbc800 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS13635 28f8e3f953c6cf563a8e78c80edbc800 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS13635 28f8e3f953c6cf563a8e78c80edbc800 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 3.4E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS02135 465b72d63fbf313883990282c53c530f 333 Gene3D G3DSA:3.10.310.10 153 320 4.1E-58 T 06-07-2017 LK06_RS02135 465b72d63fbf313883990282c53c530f 333 Gene3D G3DSA:3.10.310.10 3 152 2.0E-62 T 06-07-2017 LK06_RS02135 465b72d63fbf313883990282c53c530f 333 SUPERFAMILY SSF54506 2 331 1.23E-112 T 06-07-2017 LK06_RS02135 465b72d63fbf313883990282c53c530f 333 Pfam PF05544 Proline racemase 10 332 1.3E-122 T 06-07-2017 IPR008794 Proline racemase family LK06_RS02135 465b72d63fbf313883990282c53c530f 333 PIRSF PIRSF029792 1 333 1.8E-129 T 06-07-2017 IPR008794 Proline racemase family LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 Gene3D G3DSA:3.40.50.720 4 232 1.2E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.8E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 2.8E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 2.8E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 2.8E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 2.8E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 2.8E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 SUPERFAMILY SSF51735 3 230 2.74E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 2.5E-63 T 06-07-2017 LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 6.9E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 6.9E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 6.9E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 2.7E-9 T 06-07-2017 LK06_RS05985 c1262737fb61f01afcd36a7e533c1f95 234 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 5 230 1.0E-92 T 06-07-2017 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 LK06_RS10075 6220a180bd75096f8ac6e40364ba7fb8 202 Gene3D G3DSA:1.10.1740.10 11 108 8.0E-20 T 06-07-2017 LK06_RS10075 6220a180bd75096f8ac6e40364ba7fb8 202 SUPERFAMILY SSF88946 11 104 1.18E-17 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS10075 6220a180bd75096f8ac6e40364ba7fb8 202 Pfam PF04542 Sigma-70 region 2 32 98 7.0E-10 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS10075 6220a180bd75096f8ac6e40364ba7fb8 202 Pfam PF08281 Sigma-70, region 4 136 186 9.2E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS10075 6220a180bd75096f8ac6e40364ba7fb8 202 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 28 190 1.3E-17 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS10075 6220a180bd75096f8ac6e40364ba7fb8 202 SUPERFAMILY SSF88659 130 190 3.05E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS10075 6220a180bd75096f8ac6e40364ba7fb8 202 Gene3D G3DSA:1.10.10.10 134 191 1.9E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26165 f037f06dc0a42d558b3469e2f999e719 153 Gene3D G3DSA:3.10.450.50 13 142 8.8E-68 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS26165 f037f06dc0a42d558b3469e2f999e719 153 SUPERFAMILY SSF54427 3 145 8.78E-72 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS26165 f037f06dc0a42d558b3469e2f999e719 153 Pfam PF07080 Protein of unknown function (DUF1348) 5 142 2.0E-69 T 06-07-2017 IPR009783 Protein of unknown function DUF1348 LK06_RS04785 4c60e78f17fcd87acd0b8caeba79ac85 361 SMART SM00331 90 328 9.5E-21 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS04785 4c60e78f17fcd87acd0b8caeba79ac85 361 SUPERFAMILY SSF81606 126 327 6.28E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS04785 4c60e78f17fcd87acd0b8caeba79ac85 361 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 121 327 5.2E-38 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS19435 8dbba61d2ae36db727f76c0e43d90c90 120 Gene3D G3DSA:1.10.260.40 3 68 6.5E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS19435 8dbba61d2ae36db727f76c0e43d90c90 120 SUPERFAMILY SSF47413 7 74 2.96E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS19435 8dbba61d2ae36db727f76c0e43d90c90 120 Pfam PF13560 Helix-turn-helix domain 10 68 5.9E-8 T 06-07-2017 LK06_RS19435 8dbba61d2ae36db727f76c0e43d90c90 120 SMART SM00530 13 69 0.0011 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS12040 0bff6255cb132237221b378e02c79cdb 512 Pfam PF00854 POT family 106 468 2.5E-66 T 06-07-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 LK06_RS12040 0bff6255cb132237221b378e02c79cdb 512 Gene3D G3DSA:1.20.1250.20 42 216 3.3E-10 T 06-07-2017 LK06_RS12040 0bff6255cb132237221b378e02c79cdb 512 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 169 181 - T 06-07-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 LK06_RS12040 0bff6255cb132237221b378e02c79cdb 512 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 508 2.2E-172 T 06-07-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 LK06_RS12040 0bff6255cb132237221b378e02c79cdb 512 SUPERFAMILY SSF103473 18 226 5.36E-29 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS12040 0bff6255cb132237221b378e02c79cdb 512 SUPERFAMILY SSF103473 286 504 5.36E-29 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08825 c8913d385cbb6a5db203e4e887b17235 154 SMART SM00422 36 105 1.8E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS08825 c8913d385cbb6a5db203e4e887b17235 154 Gene3D G3DSA:1.10.1660.10 36 150 2.8E-30 T 06-07-2017 LK06_RS08825 c8913d385cbb6a5db203e4e887b17235 154 SUPERFAMILY SSF46955 36 148 1.03E-27 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS08825 c8913d385cbb6a5db203e4e887b17235 154 Pfam PF13411 MerR HTH family regulatory protein 36 97 1.0E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS08420 7d06063ec21a840b2a95e7f60335b262 467 Gene3D G3DSA:3.30.420.10 3 136 8.0E-21 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS08420 7d06063ec21a840b2a95e7f60335b262 467 SUPERFAMILY SSF53254 263 466 1.66E-53 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS08420 7d06063ec21a840b2a95e7f60335b262 467 Pfam PF13456 Reverse transcriptase-like 9 130 5.0E-18 T 06-07-2017 LK06_RS08420 7d06063ec21a840b2a95e7f60335b262 467 SUPERFAMILY SSF53098 4 129 1.1E-28 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS08420 7d06063ec21a840b2a95e7f60335b262 467 SMART SM00855 264 421 1.5E-14 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS08420 7d06063ec21a840b2a95e7f60335b262 467 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 265 459 1.9E-55 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS08420 7d06063ec21a840b2a95e7f60335b262 467 Gene3D G3DSA:3.40.50.1240 262 466 4.5E-55 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS08420 7d06063ec21a840b2a95e7f60335b262 467 PIRSF PIRSF036922 1 466 7.4E-176 T 06-07-2017 IPR014636 RNase H, phosphoglycerate mutase domain-containing LK06_RS28670 6a4a7f065755d26ac0ee78156ee166fc 164 Pfam PF13581 Histidine kinase-like ATPase domain 38 135 5.0E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS28670 6a4a7f065755d26ac0ee78156ee166fc 164 SUPERFAMILY SSF55874 46 159 1.51E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS28670 6a4a7f065755d26ac0ee78156ee166fc 164 Gene3D G3DSA:3.30.565.10 38 160 2.5E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 Gene3D G3DSA:3.40.630.10 228 437 5.5E-100 T 06-07-2017 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 Gene3D G3DSA:3.40.630.10 11 97 5.5E-100 T 06-07-2017 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 SUPERFAMILY SSF101821 99 219 6.77E-30 T 06-07-2017 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 SUPERFAMILY SSF53187 219 437 3.46E-92 T 06-07-2017 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 SUPERFAMILY SSF53187 10 98 3.46E-92 T 06-07-2017 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 Gene3D G3DSA:2.30.250.10 98 225 3.0E-37 T 06-07-2017 IPR023358 Peptidase M18, domain 2 GO:0004177 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 1 439 57.709 T 06-07-2017 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 272 290 1.0E-36 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 404 419 1.0E-36 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 315 331 1.0E-36 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 87 103 1.0E-36 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 120 140 1.0E-36 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 LK06_RS15330 d6cedc950f549188b2c916a7dbec6ebf 439 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 18 436 9.7E-121 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 LK06_RS29935 2ff32b0b944241bd64ab00cff04c5ffb 242 SMART SM00563 38 152 2.1E-36 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS29935 2ff32b0b944241bd64ab00cff04c5ffb 242 Gene3D G3DSA:3.40.1130.10 27 205 2.3E-22 T 06-07-2017 LK06_RS29935 2ff32b0b944241bd64ab00cff04c5ffb 242 Pfam PF01553 Acyltransferase 23 149 2.6E-29 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS29935 2ff32b0b944241bd64ab00cff04c5ffb 242 SUPERFAMILY SSF69593 16 209 3.27E-38 T 06-07-2017 LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 274 2.5E-59 T 06-07-2017 LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 SUPERFAMILY SSF51735 6 275 8.0E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 6.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 6.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 6.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 237 257 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS03235 958913f52a511ebae99d17b2c75122b7 276 Gene3D G3DSA:3.40.50.720 1 274 1.6E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 SMART SM00331 434 659 3.0E-38 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 Pfam PF01590 GAF domain 309 404 1.1E-7 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 SUPERFAMILY SSF55874 702 772 2.37E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 65 7.7E-7 T 06-07-2017 IPR000014 PAS domain LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 Gene3D G3DSA:3.30.565.10 696 756 2.2E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 Gene3D G3DSA:3.30.450.40 234 411 1.0E-21 T 06-07-2017 IPR029016 GAF domain-like LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 464 659 1.1E-51 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 SUPERFAMILY SSF55781 311 416 4.58E-13 T 06-07-2017 IPR029016 GAF domain-like LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 SUPERFAMILY SSF81606 452 658 3.4E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 SUPERFAMILY SSF55785 120 214 4.01E-6 T 06-07-2017 IPR000014 PAS domain LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 SUPERFAMILY SSF55785 9 97 6.7E-10 T 06-07-2017 IPR000014 PAS domain LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 SMART SM00065 238 416 0.0034 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 Pfam PF08448 PAS fold 120 216 5.2E-9 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 Gene3D G3DSA:3.30.450.20 5 97 2.0E-8 T 06-07-2017 LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 Pfam PF13581 Histidine kinase-like ATPase domain 675 781 6.0E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22685 963c2f74654d84aeeee210cb244889cd 789 Gene3D G3DSA:3.30.450.20 120 204 5.7E-6 T 06-07-2017 LK06_RS24455 830e10f7e480b2d05bb98099132994c7 174 Pfam PF00293 NUDIX domain 17 141 3.1E-20 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS24455 830e10f7e480b2d05bb98099132994c7 174 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS24455 830e10f7e480b2d05bb98099132994c7 174 PRINTS PR00502 NUDIX hydrolase family signature 48 62 8.3E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS24455 830e10f7e480b2d05bb98099132994c7 174 PRINTS PR00502 NUDIX hydrolase family signature 62 77 8.3E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS24455 830e10f7e480b2d05bb98099132994c7 174 Gene3D G3DSA:3.90.79.10 10 161 8.0E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS24455 830e10f7e480b2d05bb98099132994c7 174 SUPERFAMILY SSF55811 14 142 1.25E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS08135 025498f7623638695570eab33148ee76 295 SUPERFAMILY SSF53649 47 280 5.49E-7 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 LK06_RS08135 025498f7623638695570eab33148ee76 295 Pfam PF04185 Phosphoesterase family 66 276 3.2E-30 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 LK06_RS08135 025498f7623638695570eab33148ee76 295 Gene3D G3DSA:3.40.720.10 47 135 3.6E-4 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 LK06_RS19315 561fed56f0a7c286b9f032133308470d 336 Pfam PF03576 Peptidase family S58 1 323 6.6E-74 T 06-07-2017 IPR005321 Peptidase S58, DmpA LK06_RS19315 561fed56f0a7c286b9f032133308470d 336 Gene3D G3DSA:3.60.70.12 1 325 1.7E-89 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LK06_RS19315 561fed56f0a7c286b9f032133308470d 336 SUPERFAMILY SSF56266 1 325 8.24E-70 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LK06_RS05745 5c26e47e64bd81c483499d6201a6d719 378 Gene3D G3DSA:3.40.50.2000 186 350 6.1E-25 T 06-07-2017 LK06_RS05745 5c26e47e64bd81c483499d6201a6d719 378 Pfam PF00534 Glycosyl transferases group 1 190 347 3.9E-25 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS05745 5c26e47e64bd81c483499d6201a6d719 378 Pfam PF13579 Glycosyl transferase 4-like domain 27 171 4.0E-19 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS05745 5c26e47e64bd81c483499d6201a6d719 378 SUPERFAMILY SSF53756 26 371 3.37E-62 T 06-07-2017 LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 397 410 1.1E-10 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 93 105 1.1E-10 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 73 91 1.1E-10 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 206 219 1.1E-10 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 292 311 1.1E-10 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 SUPERFAMILY SSF51419 45 305 7.27E-52 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 244 259 - T 06-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 Gene3D G3DSA:3.20.20.10 47 288 1.9E-58 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 353 414 3.6E-8 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 68 302 1.8E-35 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 Gene3D G3DSA:2.40.37.10 289 443 6.6E-33 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LK06_RS12095 c36de20d808a45cb769e2e1728fdbbf3 461 SUPERFAMILY SSF50621 271 422 5.02E-31 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LK06_RS05160 d04486f881d11780a24e126807592994 351 SUPERFAMILY SSF51679 1 340 2.62E-72 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS05160 d04486f881d11780a24e126807592994 351 Pfam PF00296 Luciferase-like monooxygenase 17 320 3.7E-81 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS05160 d04486f881d11780a24e126807592994 351 Gene3D G3DSA:3.20.20.30 1 339 1.1E-78 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS05160 d04486f881d11780a24e126807592994 351 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 324 1.9E-115 T 06-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c LK06_RS11755 9e92f497879ac0ed998895dfed0ad4a8 305 Gene3D G3DSA:3.40.50.2020 118 225 4.2E-12 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS11755 9e92f497879ac0ed998895dfed0ad4a8 305 SUPERFAMILY SSF53271 118 225 6.36E-10 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS05360 3967c99b11ed5ed17d764ba2521f0917 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 116 3.0E-23 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS05360 3967c99b11ed5ed17d764ba2521f0917 360 Pfam PF00107 Zinc-binding dehydrogenase 190 312 8.5E-28 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS05360 3967c99b11ed5ed17d764ba2521f0917 360 Gene3D G3DSA:3.90.180.10 2 182 3.8E-56 T 06-07-2017 IPR011032 GroES-like LK06_RS05360 3967c99b11ed5ed17d764ba2521f0917 360 Gene3D G3DSA:3.40.50.720 183 302 5.9E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05360 3967c99b11ed5ed17d764ba2521f0917 360 SUPERFAMILY SSF50129 2 186 1.0E-49 T 06-07-2017 IPR011032 GroES-like LK06_RS05360 3967c99b11ed5ed17d764ba2521f0917 360 SUPERFAMILY SSF51735 151 327 2.77E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05360 3967c99b11ed5ed17d764ba2521f0917 360 SMART SM00829 12 358 1.8E-10 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS05360 3967c99b11ed5ed17d764ba2521f0917 360 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LK06_RS32410 6327b41c5fbe0b4365d04ad1d47eea25 405 Pfam PF02371 Transposase IS116/IS110/IS902 family 267 333 1.5E-8 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 LK06_RS32410 6327b41c5fbe0b4365d04ad1d47eea25 405 Pfam PF01548 Transposase 3 158 3.0E-33 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS10670 7d120816ada592b11a659ffb3b796ecd 333 Gene3D G3DSA:1.10.10.60 227 274 2.0E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS10670 7d120816ada592b11a659ffb3b796ecd 333 Pfam PF01965 DJ-1/PfpI family 69 183 5.9E-13 T 06-07-2017 IPR002818 DJ-1/PfpI LK06_RS10670 7d120816ada592b11a659ffb3b796ecd 333 Gene3D G3DSA:3.40.50.880 15 226 5.6E-42 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS10670 7d120816ada592b11a659ffb3b796ecd 333 SUPERFAMILY SSF46689 274 325 7.89E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS10670 7d120816ada592b11a659ffb3b796ecd 333 Pfam PF12833 Helix-turn-helix domain 243 322 8.2E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS10670 7d120816ada592b11a659ffb3b796ecd 333 SMART SM00342 237 320 1.2E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS10670 7d120816ada592b11a659ffb3b796ecd 333 SUPERFAMILY SSF52317 14 204 2.92E-41 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS10670 7d120816ada592b11a659ffb3b796ecd 333 SUPERFAMILY SSF46689 226 271 1.97E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS10670 7d120816ada592b11a659ffb3b796ecd 333 Gene3D G3DSA:1.10.10.60 275 323 1.6E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS21410 d087e065b1bef243ddfa562d5269ae82 78 SUPERFAMILY SSF47598 16 68 3.45E-9 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 LK06_RS21410 d087e065b1bef243ddfa562d5269ae82 78 Gene3D G3DSA:1.10.1220.10 17 60 1.5E-6 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 LK06_RS12895 3de33da12d1ac9789a2fd6b5292795c2 523 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 509 8.0E-178 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12895 3de33da12d1ac9789a2fd6b5292795c2 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 401 427 3.9E-29 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12895 3de33da12d1ac9789a2fd6b5292795c2 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 349 368 3.9E-29 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12895 3de33da12d1ac9789a2fd6b5292795c2 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 186 210 3.9E-29 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12895 3de33da12d1ac9789a2fd6b5292795c2 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 3.9E-29 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12895 3de33da12d1ac9789a2fd6b5292795c2 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 261 285 3.9E-29 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12895 3de33da12d1ac9789a2fd6b5292795c2 523 Pfam PF00361 Proton-conducting membrane transporter 139 443 9.3E-67 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS08450 ae5a52fc2b49ca39d65b3eb5c2cce97a 358 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 146 3.7E-28 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS08450 ae5a52fc2b49ca39d65b3eb5c2cce97a 358 SUPERFAMILY SSF51735 150 324 6.53E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08450 ae5a52fc2b49ca39d65b3eb5c2cce97a 358 SUPERFAMILY SSF50129 314 356 7.3E-5 T 06-07-2017 IPR011032 GroES-like LK06_RS08450 ae5a52fc2b49ca39d65b3eb5c2cce97a 358 Pfam PF00107 Zinc-binding dehydrogenase 189 310 1.2E-24 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS08450 ae5a52fc2b49ca39d65b3eb5c2cce97a 358 SUPERFAMILY SSF50129 1 181 1.43E-49 T 06-07-2017 IPR011032 GroES-like LK06_RS08450 ae5a52fc2b49ca39d65b3eb5c2cce97a 358 SMART SM00829 10 352 5.7E-7 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS08450 ae5a52fc2b49ca39d65b3eb5c2cce97a 358 Gene3D G3DSA:3.40.50.720 183 298 1.7E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08450 ae5a52fc2b49ca39d65b3eb5c2cce97a 358 Gene3D G3DSA:3.90.180.10 1 182 3.3E-57 T 06-07-2017 IPR011032 GroES-like LK06_RS08450 ae5a52fc2b49ca39d65b3eb5c2cce97a 358 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LK06_RS03710 151b658dd465ca8ac7c0c10d8d4417c6 734 SUPERFAMILY SSF51011 576 656 6.04E-20 T 06-07-2017 LK06_RS03710 151b658dd465ca8ac7c0c10d8d4417c6 734 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 387 394 - T 06-07-2017 IPR030458 Glycosyl hydrolases family 31, active site LK06_RS03710 151b658dd465ca8ac7c0c10d8d4417c6 734 SUPERFAMILY SSF51445 229 574 1.99E-80 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS03710 151b658dd465ca8ac7c0c10d8d4417c6 734 Pfam PF01055 Glycosyl hydrolases family 31 219 660 1.7E-126 T 06-07-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 LK06_RS03710 151b658dd465ca8ac7c0c10d8d4417c6 734 Pfam PF13802 Galactose mutarotase-like 121 185 9.6E-10 T 06-07-2017 IPR025887 Glycoside hydrolase family 31, N-terminal domain LK06_RS03710 151b658dd465ca8ac7c0c10d8d4417c6 734 SUPERFAMILY SSF74650 35 222 1.16E-14 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 LK06_RS18810 a7446635fefd3dfdef9c2ba4bcfaf4b2 308 Pfam PF04199 Putative cyclase 84 239 6.0E-24 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 LK06_RS18810 a7446635fefd3dfdef9c2ba4bcfaf4b2 308 SUPERFAMILY SSF102198 91 307 2.62E-25 T 06-07-2017 LK06_RS18810 a7446635fefd3dfdef9c2ba4bcfaf4b2 308 Gene3D G3DSA:3.50.30.50 86 307 2.0E-32 T 06-07-2017 LK06_RS29970 789c51bd78960bda8ff928c491e3581d 317 Gene3D G3DSA:3.30.420.40 5 140 1.2E-37 T 06-07-2017 LK06_RS29970 789c51bd78960bda8ff928c491e3581d 317 Pfam PF00480 ROK family 7 306 5.1E-65 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS29970 789c51bd78960bda8ff928c491e3581d 317 Gene3D G3DSA:3.30.420.40 141 291 1.1E-49 T 06-07-2017 LK06_RS29970 789c51bd78960bda8ff928c491e3581d 317 SUPERFAMILY SSF53067 6 308 7.3E-63 T 06-07-2017 LK06_RS29970 789c51bd78960bda8ff928c491e3581d 317 ProSitePatterns PS01125 ROK family signature. 138 165 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS31275 c0128761fabd8099725b419258d40d1b 381 PIRSF PIRSF005622 1 363 3.6E-156 T 06-07-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 LK06_RS31275 c0128761fabd8099725b419258d40d1b 381 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 5 361 1.0E-144 T 06-07-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 LK06_RS31275 c0128761fabd8099725b419258d40d1b 381 Pfam PF01924 Hydrogenase formation hypA family 13 359 1.2E-153 T 06-07-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 LK06_RS07050 ac240364b9f71359c9d191bd71804949 297 PRINTS PR00990 Ribokinase signature 104 117 5.5E-35 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS07050 ac240364b9f71359c9d191bd71804949 297 PRINTS PR00990 Ribokinase signature 209 220 5.5E-35 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS07050 ac240364b9f71359c9d191bd71804949 297 PRINTS PR00990 Ribokinase signature 6 27 5.5E-35 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS07050 ac240364b9f71359c9d191bd71804949 297 PRINTS PR00990 Ribokinase signature 171 186 5.5E-35 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS07050 ac240364b9f71359c9d191bd71804949 297 PRINTS PR00990 Ribokinase signature 33 52 5.5E-35 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS07050 ac240364b9f71359c9d191bd71804949 297 Gene3D G3DSA:3.40.1190.20 2 296 3.6E-97 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS07050 ac240364b9f71359c9d191bd71804949 297 Hamap MF_01987 Ribokinase [rbsK]. 2 294 26.985 T 06-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 LK06_RS07050 ac240364b9f71359c9d191bd71804949 297 SUPERFAMILY SSF53613 1 294 1.71E-81 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS07050 ac240364b9f71359c9d191bd71804949 297 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 292 5.7E-95 T 06-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 LK06_RS07050 ac240364b9f71359c9d191bd71804949 297 Pfam PF00294 pfkB family carbohydrate kinase 1 287 8.1E-69 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB LK06_RS01890 3ce6816e5f8e2024c5819d249360d8c9 339 Gene3D G3DSA:1.10.600.10 15 307 6.8E-76 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS01890 3ce6816e5f8e2024c5819d249360d8c9 339 SUPERFAMILY SSF48576 19 304 3.02E-73 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS01890 3ce6816e5f8e2024c5819d249360d8c9 339 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 174 199 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LK06_RS01890 3ce6816e5f8e2024c5819d249360d8c9 339 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 142 157 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LK06_RS01890 3ce6816e5f8e2024c5819d249360d8c9 339 Pfam PF00494 Squalene/phytoene synthase 29 291 2.7E-63 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 LK06_RS22600 a74b804a1d6005488d90d1dc5a9b4ba9 354 Gene3D G3DSA:1.10.10.10 4 99 3.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22600 a74b804a1d6005488d90d1dc5a9b4ba9 354 SUPERFAMILY SSF46785 10 116 8.77E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22600 a74b804a1d6005488d90d1dc5a9b4ba9 354 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 2.2E-21 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal LK06_RS32395 00c937cefdf4da89795c4c71ce616970 330 Gene3D G3DSA:1.10.260.40 16 72 1.6E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS32395 00c937cefdf4da89795c4c71ce616970 330 SUPERFAMILY SSF47413 15 71 1.04E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS32395 00c937cefdf4da89795c4c71ce616970 330 SMART SM00530 20 75 4.6E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS32395 00c937cefdf4da89795c4c71ce616970 330 Pfam PF13560 Helix-turn-helix domain 17 77 1.1E-11 T 06-07-2017 LK06_RS28925 85a9b865749b8b197d39bc55a6b6d87f 269 Pfam PF12146 Serine aminopeptidase, S33 25 250 7.9E-61 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 LK06_RS28925 85a9b865749b8b197d39bc55a6b6d87f 269 Gene3D G3DSA:3.40.50.1820 15 263 6.7E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28925 85a9b865749b8b197d39bc55a6b6d87f 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 1.7E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS28925 85a9b865749b8b197d39bc55a6b6d87f 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 1.7E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS28925 85a9b865749b8b197d39bc55a6b6d87f 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 1.7E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS28925 85a9b865749b8b197d39bc55a6b6d87f 269 SUPERFAMILY SSF53474 4 266 3.51E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS09520 df308717cb534774dcd7a55e47b8fff8 596 SUPERFAMILY SSF81606 454 568 4.45E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS09520 df308717cb534774dcd7a55e47b8fff8 596 SUPERFAMILY SSF81606 343 425 4.45E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS09520 df308717cb534774dcd7a55e47b8fff8 596 Gene3D G3DSA:3.30.450.40 152 306 6.9E-6 T 06-07-2017 IPR029016 GAF domain-like LK06_RS09520 df308717cb534774dcd7a55e47b8fff8 596 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 355 568 2.7E-46 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS09520 df308717cb534774dcd7a55e47b8fff8 596 SMART SM00331 329 569 2.4E-39 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS09520 df308717cb534774dcd7a55e47b8fff8 596 SUPERFAMILY SSF55781 181 302 5.15E-6 T 06-07-2017 IPR029016 GAF domain-like LK06_RS09520 df308717cb534774dcd7a55e47b8fff8 596 Pfam PF13581 Histidine kinase-like ATPase domain 6 92 1.5E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS09520 df308717cb534774dcd7a55e47b8fff8 596 SUPERFAMILY SSF55874 17 119 6.91E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11300 5a90f16fa7da9f89d81cc901fcfa9aee 382 Gene3D G3DSA:3.10.180.10 16 188 1.6E-44 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS11300 5a90f16fa7da9f89d81cc901fcfa9aee 382 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 23 382 7.0E-138 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 LK06_RS11300 5a90f16fa7da9f89d81cc901fcfa9aee 382 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 186 336 5.9E-17 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS11300 5a90f16fa7da9f89d81cc901fcfa9aee 382 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 23 138 2.1E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS11300 5a90f16fa7da9f89d81cc901fcfa9aee 382 SUPERFAMILY SSF54593 16 369 1.12E-90 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS11300 5a90f16fa7da9f89d81cc901fcfa9aee 382 Gene3D G3DSA:3.10.180.10 189 382 1.5E-80 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS11300 5a90f16fa7da9f89d81cc901fcfa9aee 382 PIRSF PIRSF009283 9 382 1.8E-137 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 LK06_RS26320 2a4affb15c5b4f809ad268adb2814ef1 347 Gene3D G3DSA:3.40.50.150 148 326 3.2E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26320 2a4affb15c5b4f809ad268adb2814ef1 347 SUPERFAMILY SSF53335 148 335 2.79E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26320 2a4affb15c5b4f809ad268adb2814ef1 347 Gene3D G3DSA:1.10.10.10 17 94 3.9E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25765 a8b70a3334277a910b73d46034f0085d 308 SUPERFAMILY SSF51445 41 283 5.59E-63 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS25765 a8b70a3334277a910b73d46034f0085d 308 ProSitePatterns PS01095 Chitinases family 18 active site. 161 169 - T 06-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 LK06_RS25765 a8b70a3334277a910b73d46034f0085d 308 PIRSF PIRSF001103 1 308 8.1E-137 T 06-07-2017 IPR016289 Endo-beta-N-acetylglucosaminidase GO:0005576|GO:0033925 KEGG: 00511+3.2.1.96 LK06_RS25765 a8b70a3334277a910b73d46034f0085d 308 Pfam PF00704 Glycosyl hydrolases family 18 73 272 3.0E-18 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 LK06_RS25765 a8b70a3334277a910b73d46034f0085d 308 Gene3D G3DSA:3.20.20.80 41 306 6.0E-70 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS22585 5228576f8aa7f9611222e9ff8c421d51 321 Gene3D G3DSA:3.90.180.10 7 157 3.1E-27 T 06-07-2017 IPR011032 GroES-like LK06_RS22585 5228576f8aa7f9611222e9ff8c421d51 321 SUPERFAMILY SSF51735 126 287 2.15E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22585 5228576f8aa7f9611222e9ff8c421d51 321 Gene3D G3DSA:3.40.50.720 158 267 2.2E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22585 5228576f8aa7f9611222e9ff8c421d51 321 SUPERFAMILY SSF50129 6 154 1.17E-29 T 06-07-2017 IPR011032 GroES-like LK06_RS22585 5228576f8aa7f9611222e9ff8c421d51 321 Pfam PF00107 Zinc-binding dehydrogenase 165 283 1.6E-18 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS22585 5228576f8aa7f9611222e9ff8c421d51 321 SMART SM00829 13 318 9.8E-12 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS04230 c47c0d4e79517a0c61fea5043b0a11f4 420 Gene3D G3DSA:3.30.930.10 219 319 5.7E-80 T 06-07-2017 LK06_RS04230 c47c0d4e79517a0c61fea5043b0a11f4 420 Gene3D G3DSA:3.30.930.10 3 185 5.7E-80 T 06-07-2017 LK06_RS04230 c47c0d4e79517a0c61fea5043b0a11f4 420 Gene3D G3DSA:3.40.50.800 326 418 3.9E-27 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS04230 c47c0d4e79517a0c61fea5043b0a11f4 420 SUPERFAMILY SSF55681 4 315 1.17E-79 T 06-07-2017 LK06_RS04230 c47c0d4e79517a0c61fea5043b0a11f4 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 417 30.821 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 LK06_RS04230 c47c0d4e79517a0c61fea5043b0a11f4 420 Pfam PF13393 Histidyl-tRNA synthetase 9 309 1.3E-42 T 06-07-2017 LK06_RS04230 c47c0d4e79517a0c61fea5043b0a11f4 420 SUPERFAMILY SSF52954 327 419 1.64E-22 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS04230 c47c0d4e79517a0c61fea5043b0a11f4 420 PIRSF PIRSF001549 1 419 1.4E-103 T 06-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 LK06_RS04230 c47c0d4e79517a0c61fea5043b0a11f4 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 407 1.0E-132 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 LK06_RS04230 c47c0d4e79517a0c61fea5043b0a11f4 420 Pfam PF03129 Anticodon binding domain 329 417 2.6E-13 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS22025 555cce2ea79a0d4838e9bb372bd9eb78 237 SUPERFAMILY SSF88659 148 208 4.67E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22025 555cce2ea79a0d4838e9bb372bd9eb78 237 Pfam PF08281 Sigma-70, region 4 153 204 1.3E-16 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22025 555cce2ea79a0d4838e9bb372bd9eb78 237 Gene3D G3DSA:1.10.10.10 147 209 4.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22025 555cce2ea79a0d4838e9bb372bd9eb78 237 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 51 208 6.2E-33 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22025 555cce2ea79a0d4838e9bb372bd9eb78 237 Gene3D G3DSA:1.10.1740.10 49 121 2.1E-26 T 06-07-2017 LK06_RS22025 555cce2ea79a0d4838e9bb372bd9eb78 237 Pfam PF04542 Sigma-70 region 2 55 120 1.3E-20 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22025 555cce2ea79a0d4838e9bb372bd9eb78 237 SUPERFAMILY SSF88946 51 132 5.34E-24 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12860 72996b825bc45f964b061c58fbd8c107 481 SUPERFAMILY SSF103473 261 473 1.96E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS12860 72996b825bc45f964b061c58fbd8c107 481 SUPERFAMILY SSF103473 7 206 1.96E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS12860 72996b825bc45f964b061c58fbd8c107 481 Gene3D G3DSA:1.20.1250.20 275 475 5.7E-14 T 06-07-2017 LK06_RS12860 72996b825bc45f964b061c58fbd8c107 481 Gene3D G3DSA:1.20.1250.20 26 201 3.0E-23 T 06-07-2017 LK06_RS12860 72996b825bc45f964b061c58fbd8c107 481 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 433 1.7E-74 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS12860 72996b825bc45f964b061c58fbd8c107 481 Pfam PF07690 Major Facilitator Superfamily 31 422 9.4E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS14120 d7b2c03da7e4467ec38d9f5856d09ad3 234 Gene3D G3DSA:3.90.79.10 52 216 1.7E-35 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS14120 d7b2c03da7e4467ec38d9f5856d09ad3 234 Pfam PF00293 NUDIX domain 55 175 1.8E-12 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS14120 d7b2c03da7e4467ec38d9f5856d09ad3 234 SUPERFAMILY SSF55811 42 213 1.12E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS30565 b9da02ab92b9118a93d9e163fe1e7800 434 Pfam PF00501 AMP-binding enzyme 94 290 9.5E-16 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS30565 b9da02ab92b9118a93d9e163fe1e7800 434 Gene3D G3DSA:3.30.300.30 326 430 1.6E-35 T 06-07-2017 LK06_RS30565 b9da02ab92b9118a93d9e163fe1e7800 434 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 12 429 1.3E-211 T 06-07-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 LK06_RS30565 b9da02ab92b9118a93d9e163fe1e7800 434 Gene3D G3DSA:3.40.50.980 93 246 2.2E-12 T 06-07-2017 LK06_RS30565 b9da02ab92b9118a93d9e163fe1e7800 434 SUPERFAMILY SSF56801 24 425 8.9E-66 T 06-07-2017 LK06_RS30565 b9da02ab92b9118a93d9e163fe1e7800 434 PIRSF PIRSF006444 2 431 6.3E-200 T 06-07-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 LK06_RS30565 b9da02ab92b9118a93d9e163fe1e7800 434 Pfam PF14535 AMP-binding enzyme C-terminal domain 336 429 1.6E-25 T 06-07-2017 IPR028154 AMP-dependent ligase, C-terminal LK06_RS04010 d8597fca024786de122ab8d5ebd85032 361 SUPERFAMILY SSF50331 252 347 2.32E-9 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal LK06_RS04010 d8597fca024786de122ab8d5ebd85032 361 Pfam PF08402 TOBE domain 285 351 6.4E-10 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 LK06_RS04010 d8597fca024786de122ab8d5ebd85032 361 SUPERFAMILY SSF52540 19 256 3.28E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04010 d8597fca024786de122ab8d5ebd85032 361 SMART SM00382 43 226 8.7E-21 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS04010 d8597fca024786de122ab8d5ebd85032 361 Gene3D G3DSA:3.40.50.300 9 251 2.4E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04010 d8597fca024786de122ab8d5ebd85032 361 Pfam PF00005 ABC transporter 34 176 5.4E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS04010 d8597fca024786de122ab8d5ebd85032 361 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS26070 38cc0a449d2ce3ca486e97df8893ab4a 483 Pfam PF13520 Amino acid permease 30 431 2.0E-52 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS26070 38cc0a449d2ce3ca486e97df8893ab4a 483 PIRSF PIRSF006060 7 483 5.2E-90 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS24680 2254cd4083e21ed5f98adf540417e62d 486 Gene3D G3DSA:3.40.605.10 9 282 3.6E-74 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS24680 2254cd4083e21ed5f98adf540417e62d 486 Pfam PF00171 Aldehyde dehydrogenase family 22 476 1.4E-131 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS24680 2254cd4083e21ed5f98adf540417e62d 486 Gene3D G3DSA:3.40.309.10 283 455 1.8E-55 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS24680 2254cd4083e21ed5f98adf540417e62d 486 SUPERFAMILY SSF53720 9 480 2.75E-132 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS20735 9f12d7a8bfd639ab418aac723a74a24e 255 SUPERFAMILY SSF53474 30 214 4.27E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS20735 9f12d7a8bfd639ab418aac723a74a24e 255 Pfam PF12697 Alpha/beta hydrolase family 28 166 3.1E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS20735 9f12d7a8bfd639ab418aac723a74a24e 255 Gene3D G3DSA:3.40.50.1820 57 214 1.7E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02030 b35ba22c16af307859c623e01d372bf1 638 Pfam PF04138 GtrA-like protein 11 138 9.4E-19 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 LK06_RS03280 9cae25e3799be7eb372f839522489ddb 339 Pfam PF08241 Methyltransferase domain 96 192 1.7E-10 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS03280 9cae25e3799be7eb372f839522489ddb 339 SUPERFAMILY SSF53335 69 238 1.24E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03280 9cae25e3799be7eb372f839522489ddb 339 Gene3D G3DSA:3.40.50.150 72 237 6.5E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS17400 5f602d863d4541d55797baf86cbc83a3 204 Gene3D G3DSA:1.10.357.10 8 201 2.5E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS17400 5f602d863d4541d55797baf86cbc83a3 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 5.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17400 5f602d863d4541d55797baf86cbc83a3 204 SUPERFAMILY SSF48498 90 190 1.08E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS17400 5f602d863d4541d55797baf86cbc83a3 204 SUPERFAMILY SSF46689 11 83 1.75E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS17400 5f602d863d4541d55797baf86cbc83a3 204 Pfam PF13305 WHG domain 96 178 2.5E-14 T 06-07-2017 IPR025996 WHG domain LK06_RS20030 3eb0302e03f07c73cfd80519b2a84d03 343 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 81 260 4.6E-22 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS20030 3eb0302e03f07c73cfd80519b2a84d03 343 SUPERFAMILY SSF52266 76 274 3.21E-29 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS20030 3eb0302e03f07c73cfd80519b2a84d03 343 Gene3D G3DSA:3.40.50.1110 77 272 2.4E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS18175 186a6740b626f00d7230ef0d7a6cd817 506 Gene3D G3DSA:1.20.1250.20 22 207 7.1E-29 T 06-07-2017 LK06_RS18175 186a6740b626f00d7230ef0d7a6cd817 506 Pfam PF07690 Major Facilitator Superfamily 31 425 4.5E-52 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS18175 186a6740b626f00d7230ef0d7a6cd817 506 Gene3D G3DSA:1.20.1250.20 277 490 2.1E-14 T 06-07-2017 LK06_RS18175 186a6740b626f00d7230ef0d7a6cd817 506 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 28 439 1.3E-77 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS18175 186a6740b626f00d7230ef0d7a6cd817 506 SUPERFAMILY SSF103473 262 436 8.11E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS18175 186a6740b626f00d7230ef0d7a6cd817 506 SUPERFAMILY SSF103473 22 214 8.11E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS18175 186a6740b626f00d7230ef0d7a6cd817 506 SUPERFAMILY SSF103473 463 489 8.11E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS18175 186a6740b626f00d7230ef0d7a6cd817 506 ProSitePatterns PS00216 Sugar transport proteins signature 1. 81 97 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LK06_RS08795 41e1b61a725f643a111697292965281b 915 PIRSF PIRSF000156 10 910 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LK06_RS08795 41e1b61a725f643a111697292965281b 915 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 19 908 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LK06_RS08795 41e1b61a725f643a111697292965281b 915 SUPERFAMILY SSF52518 70 482 8.35E-127 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS08795 41e1b61a725f643a111697292965281b 915 Gene3D G3DSA:3.40.50.970 488 726 2.6E-109 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS08795 41e1b61a725f643a111697292965281b 915 Gene3D G3DSA:3.40.50.970 70 483 7.5E-148 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS08795 41e1b61a725f643a111697292965281b 915 Gene3D G3DSA:3.40.50.920 730 903 8.7E-67 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS08795 41e1b61a725f643a111697292965281b 915 SUPERFAMILY SSF52922 726 900 3.31E-52 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS08795 41e1b61a725f643a111697292965281b 915 SUPERFAMILY SSF52518 488 722 7.8E-85 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS08795 41e1b61a725f643a111697292965281b 915 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 150 307 4.0E-7 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS04920 90f99383518af5af066d9e54e2f4f2ed 316 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 142 156 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS04920 90f99383518af5af066d9e54e2f4f2ed 316 Pfam PF00849 RNA pseudouridylate synthase 103 249 1.3E-19 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS04920 90f99383518af5af066d9e54e2f4f2ed 316 SUPERFAMILY SSF55120 96 300 5.92E-47 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS17870 94a07b62ce1eb6a67b81fb87a56b7a3d 250 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 114 121 - T 06-07-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 LK06_RS17870 94a07b62ce1eb6a67b81fb87a56b7a3d 250 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 14 242 1.7E-64 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 LK06_RS17870 94a07b62ce1eb6a67b81fb87a56b7a3d 250 SUPERFAMILY SSF53448 14 241 3.25E-52 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS17870 94a07b62ce1eb6a67b81fb87a56b7a3d 250 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 13 244 29.142 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 LK06_RS17870 94a07b62ce1eb6a67b81fb87a56b7a3d 250 Gene3D G3DSA:3.90.550.10 12 245 1.4E-66 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS17870 94a07b62ce1eb6a67b81fb87a56b7a3d 250 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 16 241 1.7E-70 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 262 454 1.2E-96 T 06-07-2017 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 Gene3D G3DSA:3.30.1330.100 122 210 5.7E-55 T 06-07-2017 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 Gene3D G3DSA:3.30.1330.100 7 55 5.7E-55 T 06-07-2017 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 Pfam PF01996 F420-0:Gamma-glutamyl ligase 16 72 6.0E-10 T 06-07-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 Pfam PF01996 F420-0:Gamma-glutamyl ligase 85 207 2.4E-34 T 06-07-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 Gene3D G3DSA:3.40.109.10 257 452 5.0E-39 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 Gene3D G3DSA:3.90.1660.10 58 121 1.2E-22 T 06-07-2017 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 13 454 51.662 T 06-07-2017 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 Pfam PF00881 Nitroreductase family 264 434 1.7E-26 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 10 224 1.3E-74 T 06-07-2017 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 SUPERFAMILY SSF144010 9 220 1.7E-64 T 06-07-2017 LK06_RS11915 856dbd5ba56782cfa29681cfa2da5a94 454 SUPERFAMILY SSF55469 260 452 2.22E-38 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS22310 ffc1f8168625ae6970814f4dbb7ca894 991 Pfam PF03699 Uncharacterised protein family (UPF0182) 26 815 2.2E-281 T 06-07-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 LK06_RS22310 ffc1f8168625ae6970814f4dbb7ca894 991 Hamap MF_01600 UPF0182 protein . 17 890 18.206 T 06-07-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 Gene3D G3DSA:3.40.1380.10 64 196 8.2E-38 T 06-07-2017 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 SUPERFAMILY SSF52943 3 295 6.93E-80 T 06-07-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.2E-30 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 PRINTS PR00126 ATP synthase gamma subunit signature 242 261 1.2E-30 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 PRINTS PR00126 ATP synthase gamma subunit signature 273 294 1.2E-30 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 1.2E-30 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 Pfam PF00231 ATP synthase 5 295 3.0E-84 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 Gene3D G3DSA:1.10.287.80 210 243 1.8E-27 T 06-07-2017 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 Gene3D G3DSA:1.10.287.80 20 61 1.8E-27 T 06-07-2017 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 281 294 - T 06-07-2017 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 Gene3D G3DSA:1.10.287.80 244 290 2.4E-25 T 06-07-2017 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 295 33.087 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23300 3b870de09e4f29a3dc7d253865a4cfe1 304 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 295 3.9E-91 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS08455 9811d319794389d45982bc380dd15ce5 289 SUPERFAMILY SSF54637 164 282 3.23E-30 T 06-07-2017 IPR029069 HotDog domain LK06_RS08455 9811d319794389d45982bc380dd15ce5 289 Gene3D G3DSA:3.10.129.10 1 146 2.1E-50 T 06-07-2017 IPR029069 HotDog domain LK06_RS08455 9811d319794389d45982bc380dd15ce5 289 SUPERFAMILY SSF54637 13 159 2.44E-41 T 06-07-2017 IPR029069 HotDog domain LK06_RS08455 9811d319794389d45982bc380dd15ce5 289 Pfam PF01575 MaoC like domain 164 263 1.0E-31 T 06-07-2017 IPR002539 MaoC-like domain LK06_RS08455 9811d319794389d45982bc380dd15ce5 289 Pfam PF13452 N-terminal half of MaoC dehydratase 16 133 2.0E-17 T 06-07-2017 LK06_RS08455 9811d319794389d45982bc380dd15ce5 289 Gene3D G3DSA:3.10.129.10 147 284 7.9E-45 T 06-07-2017 IPR029069 HotDog domain LK06_RS26905 d24b8e5d668f3908a474fc825a2ae814 750 SUPERFAMILY SSF82866 471 716 2.62E-31 T 06-07-2017 LK06_RS26905 d24b8e5d668f3908a474fc825a2ae814 750 SUPERFAMILY SSF82866 119 349 1.57E-29 T 06-07-2017 LK06_RS26905 d24b8e5d668f3908a474fc825a2ae814 750 Gene3D G3DSA:1.20.1640.10 500 721 1.0E-33 T 06-07-2017 LK06_RS26905 d24b8e5d668f3908a474fc825a2ae814 750 Gene3D G3DSA:1.20.1640.10 153 350 5.4E-28 T 06-07-2017 LK06_RS26905 d24b8e5d668f3908a474fc825a2ae814 750 Pfam PF03176 MMPL family 75 383 9.2E-49 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS26905 d24b8e5d668f3908a474fc825a2ae814 750 Pfam PF03176 MMPL family 419 720 1.1E-35 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 Gene3D G3DSA:1.10.150.20 883 935 9.7E-5 T 06-07-2017 LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 Pfam PF00069 Protein kinase domain 533 804 2.0E-14 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 Pfam PF00069 Protein kinase domain 240 476 1.1E-8 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 Gene3D G3DSA:1.10.510.10 316 490 1.8E-12 T 06-07-2017 LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 SUPERFAMILY SSF47789 877 936 8.89E-10 T 06-07-2017 LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 SMART SM00220 532 816 8.4E-10 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 Gene3D G3DSA:1.10.510.10 645 838 4.8E-17 T 06-07-2017 LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 Gene3D G3DSA:3.30.200.20 529 625 1.3E-6 T 06-07-2017 LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 SUPERFAMILY SSF56112 525 811 4.45E-24 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 SUPERFAMILY SSF56112 210 483 2.05E-20 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 538 566 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 Pfam PF08378 Nuclease-related domain 16 128 5.8E-17 T 06-07-2017 IPR011528 Nuclease-related domain, NERD LK06_RS01870 22b5bf7e92cd484ec036cca584bbbfc5 1565 Gene3D G3DSA:3.30.200.20 237 315 1.9E-4 T 06-07-2017 LK06_RS24260 3d4d3141b7a36a87df9bd35ef491f928 612 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 41 168 2.2E-11 T 06-07-2017 LK06_RS24260 3d4d3141b7a36a87df9bd35ef491f928 612 Pfam PF00183 Hsp90 protein 281 400 2.8E-6 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 LK06_RS24260 3d4d3141b7a36a87df9bd35ef491f928 612 PRINTS PR00775 90kDa heat shock protein signature 190 208 1.7E-6 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal LK06_RS24260 3d4d3141b7a36a87df9bd35ef491f928 612 PRINTS PR00775 90kDa heat shock protein signature 38 60 1.7E-6 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal LK06_RS24260 3d4d3141b7a36a87df9bd35ef491f928 612 PRINTS PR00775 90kDa heat shock protein signature 172 189 1.7E-6 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal LK06_RS24260 3d4d3141b7a36a87df9bd35ef491f928 612 PRINTS PR00775 90kDa heat shock protein signature 17 37 1.7E-6 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal LK06_RS24260 3d4d3141b7a36a87df9bd35ef491f928 612 SUPERFAMILY SSF54211 219 450 9.1E-40 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS24260 3d4d3141b7a36a87df9bd35ef491f928 612 SUPERFAMILY SSF55874 19 215 4.93E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24260 3d4d3141b7a36a87df9bd35ef491f928 612 PIRSF PIRSF002583 1 609 4.2E-89 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 LK06_RS24260 3d4d3141b7a36a87df9bd35ef491f928 612 Gene3D G3DSA:3.30.565.10 18 215 2.0E-46 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22300 30a4cc9a804bd9775672ce7eab8e8ebb 358 Pfam PF13180 PDZ domain 131 190 4.2E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS22300 30a4cc9a804bd9775672ce7eab8e8ebb 358 Gene3D G3DSA:3.30.230.10 245 340 1.1E-20 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS22300 30a4cc9a804bd9775672ce7eab8e8ebb 358 Gene3D G3DSA:2.30.42.10 123 190 2.8E-13 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS22300 30a4cc9a804bd9775672ce7eab8e8ebb 358 SMART SM00228 124 190 2.1E-4 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS22300 30a4cc9a804bd9775672ce7eab8e8ebb 358 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 248 337 3.2E-7 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 LK06_RS22300 30a4cc9a804bd9775672ce7eab8e8ebb 358 SUPERFAMILY SSF50156 133 248 4.73E-13 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS22300 30a4cc9a804bd9775672ce7eab8e8ebb 358 SUPERFAMILY SSF54211 216 340 1.86E-19 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 Gene3D G3DSA:3.50.50.60 102 172 1.7E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 Gene3D G3DSA:3.50.50.60 273 396 1.7E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 Gene3D G3DSA:3.50.50.60 8 48 1.7E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 SUPERFAMILY SSF51395 402 747 5.62E-113 T 06-07-2017 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 Gene3D G3DSA:3.20.20.70 403 744 6.4E-119 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 Pfam PF01494 FAD binding domain 137 342 1.5E-15 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 SUPERFAMILY SSF51905 7 156 1.87E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 SUPERFAMILY SSF51905 270 361 1.87E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 407 738 1.8E-60 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 2.1E-13 T 06-07-2017 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 347 2.1E-13 T 06-07-2017 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 135 150 2.1E-13 T 06-07-2017 LK06_RS26085 5ce38666da93662070cf4c0ccfad6551 779 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.1E-13 T 06-07-2017 LK06_RS27190 b48cda10363edb8033910fa800e233ca 301 SUPERFAMILY SSF48179 174 299 8.84E-24 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS27190 b48cda10363edb8033910fa800e233ca 301 Gene3D G3DSA:3.40.50.720 2 180 2.0E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27190 b48cda10363edb8033910fa800e233ca 301 Pfam PF02153 Prephenate dehydrogenase 70 277 1.1E-20 T 06-07-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 LK06_RS27190 b48cda10363edb8033910fa800e233ca 301 SUPERFAMILY SSF51735 70 172 4.4E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27190 b48cda10363edb8033910fa800e233ca 301 SUPERFAMILY SSF51735 2 41 4.4E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27190 b48cda10363edb8033910fa800e233ca 301 Gene3D G3DSA:1.10.3660.10 183 300 3.1E-24 T 06-07-2017 LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 SUPERFAMILY SSF46894 928 1001 4.42E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 SMART SM00421 937 994 3.3E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 SUPERFAMILY SSF52540 125 248 6.18E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 SUPERFAMILY SSF52540 2 74 6.18E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 Gene3D G3DSA:1.25.40.10 822 900 2.0E-16 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 Gene3D G3DSA:1.25.40.10 540 775 2.0E-16 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 940 954 4.7E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 954 970 4.7E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 970 982 4.7E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 Gene3D G3DSA:3.40.50.300 117 200 4.9E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 Gene3D G3DSA:3.40.50.300 2 71 4.9E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 Pfam PF13191 AAA ATPase domain 2 180 9.5E-29 T 06-07-2017 LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 SUPERFAMILY SSF48452 543 691 2.09E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 Gene3D G3DSA:1.10.10.10 932 999 4.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23925 f60108870fabd62cea26129b8f5573e3 1011 Pfam PF00196 Bacterial regulatory proteins, luxR family 940 994 1.5E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26230 1546936ddd18d3ce6f6055a578cefb46 348 Pfam PF04303 PrpF protein 50 312 1.5E-19 T 06-07-2017 IPR007400 PrpF protein LK06_RS26230 1546936ddd18d3ce6f6055a578cefb46 348 Gene3D G3DSA:3.10.310.10 50 129 2.0E-7 T 06-07-2017 LK06_RS26230 1546936ddd18d3ce6f6055a578cefb46 348 SUPERFAMILY SSF54506 151 314 8.63E-26 T 06-07-2017 LK06_RS26230 1546936ddd18d3ce6f6055a578cefb46 348 Gene3D G3DSA:3.10.310.10 151 307 1.1E-25 T 06-07-2017 LK06_RS26230 1546936ddd18d3ce6f6055a578cefb46 348 SUPERFAMILY SSF54506 47 133 4.47E-12 T 06-07-2017 LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 SUPERFAMILY SSF55785 6 90 1.1E-14 T 06-07-2017 IPR000014 PAS domain LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 SMART SM00091 2 60 15.0 T 06-07-2017 IPR000014 PAS domain LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 SMART SM00091 98 165 0.0037 T 06-07-2017 IPR000014 PAS domain LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 SMART SM00331 430 647 4.9E-31 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 457 646 1.6E-50 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 Gene3D G3DSA:3.30.450.20 101 213 1.3E-9 T 06-07-2017 LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 Pfam PF13581 Histidine kinase-like ATPase domain 661 755 1.2E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 Gene3D G3DSA:3.30.450.20 6 92 1.3E-11 T 06-07-2017 LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 SMART SM00065 219 409 2.0E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 SUPERFAMILY SSF81606 444 646 7.06E-7 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 Pfam PF08448 PAS fold 106 215 2.0E-11 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 SUPERFAMILY SSF55781 275 410 8.94E-12 T 06-07-2017 IPR029016 GAF domain-like LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 SUPERFAMILY SSF55785 101 204 1.17E-10 T 06-07-2017 IPR000014 PAS domain LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 2 92 4.8E-9 T 06-07-2017 IPR000014 PAS domain LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 Pfam PF00989 PAS fold 6 93 1.3E-11 T 06-07-2017 IPR013767 PAS fold GO:0006355 LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 Gene3D G3DSA:3.30.450.40 224 406 4.4E-29 T 06-07-2017 IPR029016 GAF domain-like LK06_RS31040 604c44e3ba518ddf974f1c6a4e673d82 776 Pfam PF01590 GAF domain 304 399 3.0E-7 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS06960 d1785a1fa763a5ca1103a39b86ecd56c 110 Pfam PF01817 Chorismate mutase type II 23 98 7.6E-17 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS06960 d1785a1fa763a5ca1103a39b86ecd56c 110 SUPERFAMILY SSF48600 12 102 2.29E-25 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS06960 d1785a1fa763a5ca1103a39b86ecd56c 110 SMART SM00830 23 103 2.2E-21 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS06960 d1785a1fa763a5ca1103a39b86ecd56c 110 Gene3D G3DSA:1.20.59.10 12 101 8.7E-21 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS06960 d1785a1fa763a5ca1103a39b86ecd56c 110 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 15 106 1.7E-48 T 06-07-2017 IPR010951 Chorismate mutase, bacteria LK06_RS21810 4a0fc7061902aea649597447a2f7d0b6 731 SUPERFAMILY SSF53850 545 717 2.85E-24 T 06-07-2017 LK06_RS21810 4a0fc7061902aea649597447a2f7d0b6 731 Gene3D G3DSA:3.40.190.10 188 337 3.7E-17 T 06-07-2017 LK06_RS21810 4a0fc7061902aea649597447a2f7d0b6 731 SUPERFAMILY SSF53850 55 288 3.8E-48 T 06-07-2017 LK06_RS21810 4a0fc7061902aea649597447a2f7d0b6 731 SUPERFAMILY SSF53850 345 444 3.8E-48 T 06-07-2017 LK06_RS21810 4a0fc7061902aea649597447a2f7d0b6 731 Gene3D G3DSA:3.90.76.10 94 187 2.9E-9 T 06-07-2017 LK06_RS21810 4a0fc7061902aea649597447a2f7d0b6 731 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 342 448 2.2E-12 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS21810 4a0fc7061902aea649597447a2f7d0b6 731 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 117 337 3.5E-24 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS21810 4a0fc7061902aea649597447a2f7d0b6 731 Gene3D G3DSA:3.10.105.10 361 441 8.9E-62 T 06-07-2017 LK06_RS21810 4a0fc7061902aea649597447a2f7d0b6 731 Gene3D G3DSA:3.10.105.10 546 690 8.9E-62 T 06-07-2017 LK06_RS06310 e6e962b4ab8524fe9b37b3a09d14271d 264 SUPERFAMILY SSF52540 6 239 5.2E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06310 e6e962b4ab8524fe9b37b3a09d14271d 264 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS06310 e6e962b4ab8524fe9b37b3a09d14271d 264 SMART SM00382 30 217 4.2E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS06310 e6e962b4ab8524fe9b37b3a09d14271d 264 Pfam PF00005 ABC transporter 21 169 8.4E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS06310 e6e962b4ab8524fe9b37b3a09d14271d 264 PIRSF PIRSF039085 2 245 8.0E-111 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LK06_RS06310 e6e962b4ab8524fe9b37b3a09d14271d 264 Gene3D G3DSA:3.40.50.300 6 240 1.1E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13425 648e9ccebe02a9c7e5adf1ece9ed46b2 577 SUPERFAMILY SSF69742 2 158 2.09E-43 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LK06_RS13425 648e9ccebe02a9c7e5adf1ece9ed46b2 577 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 281 1.1E-77 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LK06_RS13425 648e9ccebe02a9c7e5adf1ece9ed46b2 577 SUPERFAMILY SSF69075 454 556 3.01E-16 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LK06_RS13425 648e9ccebe02a9c7e5adf1ece9ed46b2 577 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 184 281 4.8E-18 T 06-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase LK06_RS13425 648e9ccebe02a9c7e5adf1ece9ed46b2 577 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 5.9E-44 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LK06_RS13425 648e9ccebe02a9c7e5adf1ece9ed46b2 577 SUPERFAMILY SSF51735 182 274 5.31E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13425 648e9ccebe02a9c7e5adf1ece9ed46b2 577 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 553 25.528 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LK06_RS13425 648e9ccebe02a9c7e5adf1ece9ed46b2 577 Gene3D G3DSA:3.40.50.720 183 280 4.5E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13425 648e9ccebe02a9c7e5adf1ece9ed46b2 577 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 06-07-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LK06_RS13425 648e9ccebe02a9c7e5adf1ece9ed46b2 577 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 456 555 4.7E-20 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LK06_RS23260 3028105b287dd6d6b62d9c23e881e8e3 412 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 11 411 45.355 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS23260 3028105b287dd6d6b62d9c23e881e8e3 412 Gene3D G3DSA:3.40.640.10 41 287 5.9E-95 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS23260 3028105b287dd6d6b62d9c23e881e8e3 412 Gene3D G3DSA:3.90.1150.10 288 410 4.2E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS23260 3028105b287dd6d6b62d9c23e881e8e3 412 PIRSF PIRSF000412 3 406 3.6E-142 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS23260 3028105b287dd6d6b62d9c23e881e8e3 412 Pfam PF00464 Serine hydroxymethyltransferase 13 382 5.0E-130 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS23260 3028105b287dd6d6b62d9c23e881e8e3 412 SUPERFAMILY SSF53383 8 411 6.05E-145 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS02830 fc5df90e521d4c460770420fc3d54a2c 181 Gene3D G3DSA:3.40.470.10 17 179 3.7E-56 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS02830 fc5df90e521d4c460770420fc3d54a2c 181 SMART SM00987 18 179 9.3E-9 T 06-07-2017 LK06_RS02830 fc5df90e521d4c460770420fc3d54a2c 181 SMART SM00986 18 179 9.3E-9 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS02830 fc5df90e521d4c460770420fc3d54a2c 181 Pfam PF03167 Uracil DNA glycosylase superfamily 21 169 1.5E-25 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS02830 fc5df90e521d4c460770420fc3d54a2c 181 SUPERFAMILY SSF52141 17 176 2.13E-45 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS29185 17f599f530556c0ce623957a86e672cc 352 Gene3D G3DSA:3.40.50.720 153 305 6.0E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29185 17f599f530556c0ce623957a86e672cc 352 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 28 325 5.3E-29 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LK06_RS29185 17f599f530556c0ce623957a86e672cc 352 PIRSF PIRSF001439 5 334 2.5E-67 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LK06_RS29185 17f599f530556c0ce623957a86e672cc 352 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 11 335 1.7E-117 T 06-07-2017 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB LK06_RS29185 17f599f530556c0ce623957a86e672cc 352 Gene3D G3DSA:3.30.1780.10 12 152 5.5E-39 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 LK06_RS29185 17f599f530556c0ce623957a86e672cc 352 SUPERFAMILY SSF51735 12 334 4.05E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS21855 351eb7a843688ad3ad3142e60f2b429d 246 Pfam PF13649 Methyltransferase domain 38 131 1.5E-16 T 06-07-2017 LK06_RS21855 351eb7a843688ad3ad3142e60f2b429d 246 Gene3D G3DSA:3.40.50.150 198 227 7.6E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS21855 351eb7a843688ad3ad3142e60f2b429d 246 Gene3D G3DSA:3.40.50.150 19 156 7.6E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS21855 351eb7a843688ad3ad3142e60f2b429d 246 SUPERFAMILY SSF53335 12 245 6.44E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS23025 55433503ef1b03a1648dc30b1ecab581 567 SUPERFAMILY SSF52540 122 534 2.71E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23025 55433503ef1b03a1648dc30b1ecab581 567 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 144 542 6.7E-27 T 06-07-2017 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 LK06_RS23025 55433503ef1b03a1648dc30b1ecab581 567 Gene3D G3DSA:3.40.50.300 338 535 7.8E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23025 55433503ef1b03a1648dc30b1ecab581 567 Gene3D G3DSA:3.40.50.300 95 206 7.8E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24230 b816c285393dc3b5c28274297c1780ae 77 Gene3D G3DSA:3.30.70.920 4 75 2.1E-18 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS24230 b816c285393dc3b5c28274297c1780ae 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 2.3E-13 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS24230 b816c285393dc3b5c28274297c1780ae 77 SUPERFAMILY SSF54909 2 75 9.65E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS00370 845297d8198ac9d525b4191717489c91 569 Pfam PF00005 ABC transporter 313 466 1.1E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS00370 845297d8198ac9d525b4191717489c91 569 Pfam PF00005 ABC transporter 36 192 1.6E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS00370 845297d8198ac9d525b4191717489c91 569 ProSitePatterns PS00211 ABC transporters family signature. 438 452 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS00370 845297d8198ac9d525b4191717489c91 569 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS00370 845297d8198ac9d525b4191717489c91 569 SUPERFAMILY SSF52540 15 264 1.33E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00370 845297d8198ac9d525b4191717489c91 569 Gene3D G3DSA:3.40.50.300 14 266 3.1E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00370 845297d8198ac9d525b4191717489c91 569 SUPERFAMILY SSF52540 294 535 3.62E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00370 845297d8198ac9d525b4191717489c91 569 SMART SM00382 44 242 8.9E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS00370 845297d8198ac9d525b4191717489c91 569 SMART SM00382 322 523 4.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS00370 845297d8198ac9d525b4191717489c91 569 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 275 2.2E-4 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS00370 845297d8198ac9d525b4191717489c91 569 Gene3D G3DSA:3.40.50.300 286 545 5.6E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 SUPERFAMILY SSF50465 300 389 9.21E-25 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 Gene3D G3DSA:2.40.30.10 211 295 1.6E-29 T 06-07-2017 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 388 2.1E-169 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 SUPERFAMILY SSF52540 8 225 5.4E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 Pfam PF03143 Elongation factor Tu C-terminal domain 296 388 4.5E-20 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 SUPERFAMILY SSF50447 204 298 1.06E-25 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 Pfam PF00009 Elongation factor Tu GTP binding domain 10 200 3.2E-53 T 06-07-2017 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.3E-23 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.3E-23 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.3E-23 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.3E-23 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.3E-23 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 Gene3D G3DSA:2.40.30.10 298 388 1.1E-30 T 06-07-2017 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 148 1.0E-12 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 Gene3D G3DSA:3.40.50.300 8 210 8.3E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 Pfam PF03144 Elongation factor Tu domain 2 224 290 1.2E-13 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LK06_RS03080 651f2eafc9a13c15ae0ef0fbfba6dadf 390 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 390 52.438 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LK06_RS11675 7dd65e23f778fc454b2b6d45a2009923 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 75 1.7E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS11675 7dd65e23f778fc454b2b6d45a2009923 207 Gene3D G3DSA:1.10.10.60 24 68 2.1E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS11675 7dd65e23f778fc454b2b6d45a2009923 207 Gene3D G3DSA:1.10.357.10 69 206 1.5E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS11675 7dd65e23f778fc454b2b6d45a2009923 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 42 73 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS11675 7dd65e23f778fc454b2b6d45a2009923 207 SUPERFAMILY SSF48498 88 204 2.97E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS11675 7dd65e23f778fc454b2b6d45a2009923 207 SUPERFAMILY SSF46689 24 78 2.29E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS11675 7dd65e23f778fc454b2b6d45a2009923 207 Pfam PF16859 Bacterial transcriptional repressor C-terminal 87 199 9.3E-27 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS31830 e811d7da7f1d76531035d1f566b4aa05 314 SUPERFAMILY SSF53850 109 313 1.0E-38 T 06-07-2017 LK06_RS31830 e811d7da7f1d76531035d1f566b4aa05 314 Gene3D G3DSA:3.40.190.10 109 189 3.5E-17 T 06-07-2017 LK06_RS31830 e811d7da7f1d76531035d1f566b4aa05 314 Pfam PF03466 LysR substrate binding domain 106 312 2.0E-44 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS31830 e811d7da7f1d76531035d1f566b4aa05 314 Gene3D G3DSA:3.40.190.10 190 281 2.5E-19 T 06-07-2017 LK06_RS31830 e811d7da7f1d76531035d1f566b4aa05 314 Gene3D G3DSA:1.10.10.10 19 98 2.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31830 e811d7da7f1d76531035d1f566b4aa05 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 80 1.5E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31830 e811d7da7f1d76531035d1f566b4aa05 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 57 7.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31830 e811d7da7f1d76531035d1f566b4aa05 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 57 68 7.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31830 e811d7da7f1d76531035d1f566b4aa05 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 47 7.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31830 e811d7da7f1d76531035d1f566b4aa05 314 SUPERFAMILY SSF46785 19 129 1.88E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25505 05d80ed0816d483c11ec4b5c0f67fd0d 254 Pfam PF11361 Protein of unknown function (DUF3159) 31 216 1.6E-55 T 06-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 LK06_RS25505 05d80ed0816d483c11ec4b5c0f67fd0d 254 PIRSF PIRSF010219 2 231 3.3E-83 T 06-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 LK06_RS12810 cf08b72f591d7d5cb1e3bed377ef0321 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 317 2.5E-60 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS12810 cf08b72f591d7d5cb1e3bed377ef0321 353 Gene3D G3DSA:3.40.50.1100 59 165 1.7E-27 T 06-07-2017 LK06_RS12810 cf08b72f591d7d5cb1e3bed377ef0321 353 Gene3D G3DSA:3.40.50.1100 21 58 5.5E-49 T 06-07-2017 LK06_RS12810 cf08b72f591d7d5cb1e3bed377ef0321 353 Gene3D G3DSA:3.40.50.1100 171 334 5.5E-49 T 06-07-2017 LK06_RS12810 cf08b72f591d7d5cb1e3bed377ef0321 353 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 25 332 2.8E-120 T 06-07-2017 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA LK06_RS12810 cf08b72f591d7d5cb1e3bed377ef0321 353 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 49 67 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 LK06_RS12810 cf08b72f591d7d5cb1e3bed377ef0321 353 SUPERFAMILY SSF53686 21 336 7.46E-79 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS11420 6fbb41196543eaa1089af45fdbebdd10 190 Gene3D G3DSA:3.40.1740.10 131 176 4.5E-28 T 06-07-2017 LK06_RS11420 6fbb41196543eaa1089af45fdbebdd10 190 Gene3D G3DSA:3.40.1740.10 2 44 4.5E-28 T 06-07-2017 LK06_RS11420 6fbb41196543eaa1089af45fdbebdd10 190 Pfam PF02622 Uncharacterized ACR, COG1678 16 173 2.8E-36 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 LK06_RS11420 6fbb41196543eaa1089af45fdbebdd10 190 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 5 187 26.866 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 LK06_RS11420 6fbb41196543eaa1089af45fdbebdd10 190 SUPERFAMILY SSF143456 4 184 3.92E-47 T 06-07-2017 LK06_RS25510 1d7123395548e4e7146d628b5e4c5bf5 223 Gene3D G3DSA:3.30.70.1450 147 217 1.4E-11 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS25510 1d7123395548e4e7146d628b5e4c5bf5 223 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 5.0E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS25510 1d7123395548e4e7146d628b5e4c5bf5 223 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 5.0E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS25510 1d7123395548e4e7146d628b5e4c5bf5 223 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 5.0E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS25510 1d7123395548e4e7146d628b5e4c5bf5 223 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 5.0E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS25510 1d7123395548e4e7146d628b5e4c5bf5 223 Pfam PF02080 TrkA-C domain 149 216 1.3E-10 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS25510 1d7123395548e4e7146d628b5e4c5bf5 223 SUPERFAMILY SSF51735 1 145 2.05E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25510 1d7123395548e4e7146d628b5e4c5bf5 223 SUPERFAMILY SSF116726 133 216 9.29E-13 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS25510 1d7123395548e4e7146d628b5e4c5bf5 223 Pfam PF02254 TrkA-N domain 3 118 1.8E-24 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LK06_RS25510 1d7123395548e4e7146d628b5e4c5bf5 223 Gene3D G3DSA:3.40.50.720 1 132 2.1E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS10280 94a20c48c4ca29dcc18006718cc14b01 129 Gene3D G3DSA:1.10.10.10 16 85 1.2E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS10280 94a20c48c4ca29dcc18006718cc14b01 129 Pfam PF03965 Penicillinase repressor 15 121 2.0E-19 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 LK06_RS10280 94a20c48c4ca29dcc18006718cc14b01 129 SUPERFAMILY SSF46785 17 122 1.87E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04310 cb20ffdd4991c82c31fca22aeca30ea2 301 ProSitePatterns PS01235 PdxS/SNZ family signature. 212 230 - T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 LK06_RS04310 cb20ffdd4991c82c31fca22aeca30ea2 301 SUPERFAMILY SSF51366 25 271 2.45E-63 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 LK06_RS04310 cb20ffdd4991c82c31fca22aeca30ea2 301 Pfam PF01680 SOR/SNZ family 14 219 1.4E-107 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 LK06_RS04310 cb20ffdd4991c82c31fca22aeca30ea2 301 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 11 301 52.018 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 LK06_RS04310 cb20ffdd4991c82c31fca22aeca30ea2 301 Gene3D G3DSA:3.20.20.70 199 285 1.1E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS04310 cb20ffdd4991c82c31fca22aeca30ea2 301 Gene3D G3DSA:3.20.20.70 31 167 1.1E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS04310 cb20ffdd4991c82c31fca22aeca30ea2 301 PIRSF PIRSF029271 2 301 1.7E-151 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 LK06_RS04310 cb20ffdd4991c82c31fca22aeca30ea2 301 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 16 301 7.0E-143 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 LK06_RS01485 692e1b4fcae36a4277a008daef0e1cc1 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 55 1.4E-17 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS01485 692e1b4fcae36a4277a008daef0e1cc1 333 SUPERFAMILY SSF47413 7 67 4.35E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS01485 692e1b4fcae36a4277a008daef0e1cc1 333 Gene3D G3DSA:1.10.260.40 8 61 1.8E-25 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS01485 692e1b4fcae36a4277a008daef0e1cc1 333 SMART SM00354 7 79 1.1E-20 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS01485 692e1b4fcae36a4277a008daef0e1cc1 333 Gene3D G3DSA:3.40.50.2300 178 332 1.4E-27 T 06-07-2017 LK06_RS01485 692e1b4fcae36a4277a008daef0e1cc1 333 Pfam PF13377 Periplasmic binding protein-like domain 176 333 3.4E-26 T 06-07-2017 LK06_RS01485 692e1b4fcae36a4277a008daef0e1cc1 333 Gene3D G3DSA:3.40.50.2300 62 177 1.3E-10 T 06-07-2017 LK06_RS01485 692e1b4fcae36a4277a008daef0e1cc1 333 SUPERFAMILY SSF53822 67 332 1.28E-26 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS27320 2db9fc1b18917b9113d5036b725a1c59 262 Gene3D G3DSA:2.40.10.10 37 71 6.0E-13 T 06-07-2017 LK06_RS27320 2db9fc1b18917b9113d5036b725a1c59 262 SMART SM00020 36 256 1.5E-66 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 LK06_RS27320 2db9fc1b18917b9113d5036b725a1c59 262 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 64 79 7.2E-13 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 LK06_RS27320 2db9fc1b18917b9113d5036b725a1c59 262 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 120 134 7.2E-13 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 LK06_RS27320 2db9fc1b18917b9113d5036b725a1c59 262 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 210 222 7.2E-13 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 LK06_RS27320 2db9fc1b18917b9113d5036b725a1c59 262 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 74 79 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 LK06_RS27320 2db9fc1b18917b9113d5036b725a1c59 262 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 211 222 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site LK06_RS27320 2db9fc1b18917b9113d5036b725a1c59 262 SUPERFAMILY SSF50494 31 255 1.33E-63 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS27320 2db9fc1b18917b9113d5036b725a1c59 262 Pfam PF00089 Trypsin 37 255 2.7E-54 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 LK06_RS27320 2db9fc1b18917b9113d5036b725a1c59 262 Gene3D G3DSA:2.40.10.10 72 259 2.9E-54 T 06-07-2017 LK06_RS16860 8913f80ef96ebe43a525af3d169e42bf 543 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 133 139 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LK06_RS16860 8913f80ef96ebe43a525af3d169e42bf 543 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 41 55 1.2E-14 T 06-07-2017 LK06_RS16860 8913f80ef96ebe43a525af3d169e42bf 543 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 130 142 1.2E-14 T 06-07-2017 LK06_RS16860 8913f80ef96ebe43a525af3d169e42bf 543 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 165 189 1.2E-14 T 06-07-2017 LK06_RS16860 8913f80ef96ebe43a525af3d169e42bf 543 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 12 28 1.2E-14 T 06-07-2017 LK06_RS16860 8913f80ef96ebe43a525af3d169e42bf 543 Pfam PF07669 Eco57I restriction-modification methylase 130 224 5.7E-10 T 06-07-2017 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 LK06_RS16860 8913f80ef96ebe43a525af3d169e42bf 543 Gene3D G3DSA:3.40.50.150 15 244 1.0E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS16860 8913f80ef96ebe43a525af3d169e42bf 543 SUPERFAMILY SSF53335 10 241 1.28E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 Gene3D G3DSA:1.20.120.140 107 184 2.2E-24 T 06-07-2017 LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 SMART SM00963 104 184 7.1E-25 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 Pfam PF00448 SRP54-type protein, GTPase domain 203 399 7.2E-73 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 SUPERFAMILY SSF52540 199 399 6.16E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 SUPERFAMILY SSF47364 100 178 5.1E-19 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 127 400 58.215 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 SMART SM00382 200 350 6.0E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 Pfam PF02881 SRP54-type protein, helical bundle domain 115 180 8.9E-14 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 128 398 8.1E-103 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 373 386 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 SMART SM00962 201 400 9.3E-104 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LK06_RS24360 a1960480fae646849d9a1bf5549d4b16 401 Gene3D G3DSA:3.40.50.300 195 400 8.4E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12865 23eebd2f204eca86e9553e1d2f188568 331 Gene3D G3DSA:1.10.10.10 264 327 5.7E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12865 23eebd2f204eca86e9553e1d2f188568 331 SMART SM00421 264 321 8.1E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS12865 23eebd2f204eca86e9553e1d2f188568 331 SUPERFAMILY SSF46894 255 327 4.42E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS12865 23eebd2f204eca86e9553e1d2f188568 331 Pfam PF00196 Bacterial regulatory proteins, luxR family 269 319 6.7E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS12865 23eebd2f204eca86e9553e1d2f188568 331 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 267 281 4.9E-5 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS12865 23eebd2f204eca86e9553e1d2f188568 331 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 281 297 4.9E-5 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30955 f77b9728dc0c0c49c001508e7a3b8ed3 362 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 362 79.544 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LK06_RS30955 f77b9728dc0c0c49c001508e7a3b8ed3 362 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 4 283 2.0E-68 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LK06_RS30955 f77b9728dc0c0c49c001508e7a3b8ed3 362 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 3 287 2.4E-103 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LK06_RS30955 f77b9728dc0c0c49c001508e7a3b8ed3 362 SUPERFAMILY SSF55931 2 360 5.3E-96 T 06-07-2017 LK06_RS19675 02b253d8e9d29b0bafd21fcd4d7a01d6 554 Pfam PF00905 Penicillin binding protein transpeptidase domain 278 550 2.1E-33 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS19675 02b253d8e9d29b0bafd21fcd4d7a01d6 554 SUPERFAMILY SSF56601 249 551 2.15E-51 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS19675 02b253d8e9d29b0bafd21fcd4d7a01d6 554 Gene3D G3DSA:3.40.710.10 258 552 1.1E-48 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS25960 76976fd851fb9b9e12d89cf8cc57fe81 221 Gene3D G3DSA:2.30.180.10 90 218 1.3E-32 T 06-07-2017 IPR000782 FAS1 domain LK06_RS25960 76976fd851fb9b9e12d89cf8cc57fe81 221 Pfam PF02469 Fasciclin domain 100 219 2.1E-31 T 06-07-2017 IPR000782 FAS1 domain LK06_RS25960 76976fd851fb9b9e12d89cf8cc57fe81 221 SUPERFAMILY SSF82153 81 220 1.96E-35 T 06-07-2017 IPR000782 FAS1 domain LK06_RS25960 76976fd851fb9b9e12d89cf8cc57fe81 221 SMART SM00554 123 220 8.1E-31 T 06-07-2017 IPR000782 FAS1 domain LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 SUPERFAMILY SSF48264 32 407 6.29E-93 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 Pfam PF00067 Cytochrome P450 279 376 2.1E-16 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 Pfam PF00067 Cytochrome P450 210 270 3.9E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00359 B-class P450 signature 296 323 5.7E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00359 B-class P450 signature 345 354 5.7E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00359 B-class P450 signature 95 106 5.7E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00359 B-class P450 signature 278 289 5.7E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00359 B-class P450 signature 324 339 5.7E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00359 B-class P450 signature 141 157 5.7E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00359 B-class P450 signature 158 173 5.7E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00359 B-class P450 signature 354 365 5.7E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00359 B-class P450 signature 197 219 5.7E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 Gene3D G3DSA:1.10.630.10 24 408 1.7E-117 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00385 P450 superfamily signature 278 289 6.5E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00385 P450 superfamily signature 243 260 6.5E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00385 P450 superfamily signature 354 365 6.5E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29435 3f0e3bc0b7b2da7943915b7967ccd162 414 PRINTS PR00385 P450 superfamily signature 345 354 6.5E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS28560 c0b9aba30af02b2920d5ff9dc212c8cb 263 SUPERFAMILY SSF54593 11 125 1.14E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS28560 c0b9aba30af02b2920d5ff9dc212c8cb 263 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 140 254 4.0E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS28560 c0b9aba30af02b2920d5ff9dc212c8cb 263 Gene3D G3DSA:3.10.180.10 138 257 2.3E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS28560 c0b9aba30af02b2920d5ff9dc212c8cb 263 Gene3D G3DSA:3.10.180.10 11 124 9.3E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS28560 c0b9aba30af02b2920d5ff9dc212c8cb 263 SUPERFAMILY SSF54593 138 257 1.24E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 Pfam PF01411 tRNA synthetases class II (A) 5 564 4.1E-199 T 06-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.4E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 1.4E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.4E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 1.4E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 1.4E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 662 705 3.8E-18 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 Pfam PF02272 DHHA1 domain 813 882 5.2E-11 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 SUPERFAMILY SSF55681 2 248 2.32E-92 T 06-07-2017 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 868 6.6E-263 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 SMART SM00863 662 705 2.3E-21 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 SUPERFAMILY SSF50447 461 561 7.42E-18 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 Gene3D G3DSA:3.30.930.10 1 244 7.2E-98 T 06-07-2017 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 SUPERFAMILY SSF55186 561 720 3.27E-43 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 889 171.573 T 06-07-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 LK06_RS04195 07a415efb0433a3b210fd7c06008c691 890 SUPERFAMILY SSF101353 249 444 3.01E-60 T 06-07-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 LK06_RS05305 ebb71a0e7aa09dd6c09c6c5f4264c6bf 424 Gene3D G3DSA:3.40.50.1820 235 324 4.7E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS05305 ebb71a0e7aa09dd6c09c6c5f4264c6bf 424 SUPERFAMILY SSF53474 240 321 3.1E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS24660 a007e2c2f98fe4e33e57dbff5afa58bd 201 Pfam PF01569 PAP2 superfamily 98 173 3.5E-10 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS24660 a007e2c2f98fe4e33e57dbff5afa58bd 201 SUPERFAMILY SSF48317 4 176 1.57E-19 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS24660 a007e2c2f98fe4e33e57dbff5afa58bd 201 Gene3D G3DSA:1.20.144.10 3 169 6.9E-21 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 Pfam PF13291 ACT domain 664 737 1.9E-11 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 SUPERFAMILY SSF81301 242 400 1.96E-31 T 06-07-2017 LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 SUPERFAMILY SSF55021 663 738 3.36E-7 T 06-07-2017 LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 SUPERFAMILY SSF81271 453 511 5.01E-11 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 Gene3D G3DSA:3.10.20.30 452 515 7.0E-14 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 Gene3D G3DSA:3.30.460.10 228 377 6.7E-22 T 06-07-2017 LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 SUPERFAMILY SSF109604 59 241 8.16E-62 T 06-07-2017 LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 Pfam PF13328 HD domain 78 225 1.3E-40 T 06-07-2017 IPR003607 HD/PDEase domain LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 Gene3D G3DSA:3.30.70.260 674 735 4.9E-7 T 06-07-2017 LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 Pfam PF02824 TGS domain 453 511 4.2E-16 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 Pfam PF04607 Region found in RelA / SpoT proteins 312 392 2.9E-11 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 SMART SM00954 285 405 1.1E-24 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 LK06_RS25140 b0978b1a81973a36e4294f579cfe43cd 745 SMART SM00471 93 203 2.1E-11 T 06-07-2017 IPR003607 HD/PDEase domain LK06_RS17895 d4eeb8ce0ea13b3ace41381398d95d80 552 Pfam PF07681 DoxX 232 332 9.4E-12 T 06-07-2017 IPR032808 DoxX family LK06_RS08675 ca3ea6979b97910916e450c838105cdc 244 Pfam PF14032 PknH-like extracellular domain 53 189 2.8E-7 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 LK06_RS29660 df7aa4f846d2537608698bf1562aa592 303 SUPERFAMILY SSF51735 20 98 7.48E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29660 df7aa4f846d2537608698bf1562aa592 303 Gene3D G3DSA:3.40.50.2000 247 281 6.5E-4 T 06-07-2017 LK06_RS29660 df7aa4f846d2537608698bf1562aa592 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 25 98 1.2E-10 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS29660 df7aa4f846d2537608698bf1562aa592 303 SUPERFAMILY SSF53756 151 282 8.9E-9 T 06-07-2017 LK06_RS29660 df7aa4f846d2537608698bf1562aa592 303 Gene3D G3DSA:3.40.50.720 22 99 1.2E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06360 5ee827a881be24caa772fbac9bb24997 509 SUPERFAMILY SSF53720 8 503 6.28E-83 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS06360 5ee827a881be24caa772fbac9bb24997 509 Gene3D G3DSA:3.40.309.10 256 441 1.2E-51 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS06360 5ee827a881be24caa772fbac9bb24997 509 Pfam PF00171 Aldehyde dehydrogenase family 8 446 2.4E-41 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS06360 5ee827a881be24caa772fbac9bb24997 509 Gene3D G3DSA:3.40.605.10 8 255 3.0E-35 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS02610 0e08b45c0168c08af61d00ab960c4e3c 265 Pfam PF12833 Helix-turn-helix domain 29 108 1.7E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS02610 0e08b45c0168c08af61d00ab960c4e3c 265 SMART SM00342 23 106 2.4E-31 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS02610 0e08b45c0168c08af61d00ab960c4e3c 265 SUPERFAMILY SSF46689 59 109 2.87E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02610 0e08b45c0168c08af61d00ab960c4e3c 265 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 60 102 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LK06_RS02610 0e08b45c0168c08af61d00ab960c4e3c 265 Gene3D G3DSA:1.10.10.60 62 109 2.4E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02610 0e08b45c0168c08af61d00ab960c4e3c 265 SUPERFAMILY SSF46689 7 56 1.43E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02610 0e08b45c0168c08af61d00ab960c4e3c 265 Gene3D G3DSA:1.10.10.60 6 61 3.4E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02610 0e08b45c0168c08af61d00ab960c4e3c 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 75 90 8.1E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LK06_RS02610 0e08b45c0168c08af61d00ab960c4e3c 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 90 106 8.1E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LK06_RS01115 cf6ffdd3b1f120597728e3a9d7b42f5f 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 176 4.7E-21 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01115 cf6ffdd3b1f120597728e3a9d7b42f5f 182 Pfam PF08281 Sigma-70, region 4 139 174 6.7E-8 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01115 cf6ffdd3b1f120597728e3a9d7b42f5f 182 SUPERFAMILY SSF88946 7 106 4.97E-22 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01115 cf6ffdd3b1f120597728e3a9d7b42f5f 182 SUPERFAMILY SSF88659 122 179 1.03E-8 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01115 cf6ffdd3b1f120597728e3a9d7b42f5f 182 Pfam PF04542 Sigma-70 region 2 25 92 4.3E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01115 cf6ffdd3b1f120597728e3a9d7b42f5f 182 Gene3D G3DSA:1.10.10.10 119 179 3.2E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01115 cf6ffdd3b1f120597728e3a9d7b42f5f 182 Gene3D G3DSA:1.10.1740.10 8 104 2.7E-23 T 06-07-2017 LK06_RS32115 8a7fb840fc8129570ae94c4b0e71aa4f 639 Gene3D G3DSA:3.20.20.240 159 569 5.8E-137 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS32115 8a7fb840fc8129570ae94c4b0e71aa4f 639 SUPERFAMILY SSF52242 7 133 9.58E-13 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS32115 8a7fb840fc8129570ae94c4b0e71aa4f 639 Gene3D G3DSA:3.90.970.10 570 636 9.9E-13 T 06-07-2017 IPR014714 Glutamate mutase E subunit, C-terminal domain GO:0016866|GO:0019670|GO:0031419 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 LK06_RS32115 8a7fb840fc8129570ae94c4b0e71aa4f 639 SUPERFAMILY SSF51703 159 611 2.55E-129 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS32115 8a7fb840fc8129570ae94c4b0e71aa4f 639 TIGRFAM TIGR01503 MthylAspMut_E: methylaspartate mutase, E subunit 159 628 3.0E-133 T 06-07-2017 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 LK06_RS32115 8a7fb840fc8129570ae94c4b0e71aa4f 639 Pfam PF02310 B12 binding domain 9 70 2.0E-7 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS32115 8a7fb840fc8129570ae94c4b0e71aa4f 639 Pfam PF06368 Methylaspartate mutase E chain (MutE) 210 630 2.8E-139 T 06-07-2017 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 LK06_RS32115 8a7fb840fc8129570ae94c4b0e71aa4f 639 Gene3D G3DSA:3.40.50.280 6 129 9.2E-10 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS27970 91d000d1712c725b9f8e93812d7aa443 404 Gene3D G3DSA:2.40.110.10 125 234 8.8E-33 T 06-07-2017 LK06_RS27970 91d000d1712c725b9f8e93812d7aa443 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 5.9E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS27970 91d000d1712c725b9f8e93812d7aa443 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 233 2.7E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS27970 91d000d1712c725b9f8e93812d7aa443 404 SUPERFAMILY SSF47203 248 400 2.74E-54 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS27970 91d000d1712c725b9f8e93812d7aa443 404 Gene3D G3DSA:1.10.540.10 9 123 3.9E-38 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS27970 91d000d1712c725b9f8e93812d7aa443 404 SUPERFAMILY SSF56645 9 256 1.83E-71 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS27970 91d000d1712c725b9f8e93812d7aa443 404 Gene3D G3DSA:1.20.140.10 235 401 4.3E-61 T 06-07-2017 LK06_RS27970 91d000d1712c725b9f8e93812d7aa443 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 248 397 1.3E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS04350 5f44598cc6aca977b429a1aababf8efc 218 Pfam PF07885 Ion channel 138 204 1.4E-15 T 06-07-2017 IPR013099 Potassium channel domain LK06_RS04350 5f44598cc6aca977b429a1aababf8efc 218 Gene3D G3DSA:1.20.5.110 169 205 1.6E-14 T 06-07-2017 LK06_RS04350 5f44598cc6aca977b429a1aababf8efc 218 SUPERFAMILY SSF81324 17 203 4.71E-31 T 06-07-2017 LK06_RS04350 5f44598cc6aca977b429a1aababf8efc 218 Gene3D G3DSA:1.10.287.70 113 167 1.5E-14 T 06-07-2017 LK06_RS30770 07045836bc9accb4123714674d157feb 779 SMART SM00240 139 190 9.2E-16 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS30770 07045836bc9accb4123714674d157feb 779 SMART SM00240 29 79 1.6E-6 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS30770 07045836bc9accb4123714674d157feb 779 SUPERFAMILY SSF49879 14 115 8.8E-21 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS30770 07045836bc9accb4123714674d157feb 779 SMART SM00382 252 446 1.6E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS30770 07045836bc9accb4123714674d157feb 779 Pfam PF00498 FHA domain 141 204 4.5E-17 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS30770 07045836bc9accb4123714674d157feb 779 Pfam PF00498 FHA domain 30 93 1.4E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS30770 07045836bc9accb4123714674d157feb 779 Pfam PF01061 ABC-2 type transporter 515 722 1.7E-20 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS30770 07045836bc9accb4123714674d157feb 779 ProSitePatterns PS00211 ABC transporters family signature. 362 376 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS30770 07045836bc9accb4123714674d157feb 779 SUPERFAMILY SSF52540 219 445 2.5E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30770 07045836bc9accb4123714674d157feb 779 Pfam PF00005 ABC transporter 243 390 3.7E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS30770 07045836bc9accb4123714674d157feb 779 Gene3D G3DSA:2.60.200.20 130 211 5.3E-25 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS30770 07045836bc9accb4123714674d157feb 779 Gene3D G3DSA:2.60.200.20 14 97 2.1E-20 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS30770 07045836bc9accb4123714674d157feb 779 SUPERFAMILY SSF49879 115 227 1.4E-26 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS30770 07045836bc9accb4123714674d157feb 779 Gene3D G3DSA:3.40.50.300 220 450 8.7E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24875 12e10089e15d3b052df02e76af711acd 95 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 1.0E-37 T 06-07-2017 LK06_RS24875 12e10089e15d3b052df02e76af711acd 95 SMART SM01387 8 88 1.1E-52 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24875 12e10089e15d3b052df02e76af711acd 95 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24875 12e10089e15d3b052df02e76af711acd 95 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 9.1E-38 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24875 12e10089e15d3b052df02e76af711acd 95 SUPERFAMILY SSF47060 3 89 2.44E-35 T 06-07-2017 IPR009068 S15/NS1, RNA-binding LK06_RS24875 12e10089e15d3b052df02e76af711acd 95 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.349 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24875 12e10089e15d3b052df02e76af711acd 95 Pfam PF00312 Ribosomal protein S15 8 88 2.9E-37 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24875 12e10089e15d3b052df02e76af711acd 95 Gene3D G3DSA:1.10.287.10 3 89 4.2E-39 T 06-07-2017 IPR009068 S15/NS1, RNA-binding LK06_RS17305 35d0519f1d0daafe67e5de87c1c389fb 600 Pfam PF08305 NPCBM/NEW2 domain 462 598 1.0E-28 T 06-07-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module LK06_RS17305 35d0519f1d0daafe67e5de87c1c389fb 600 Gene3D G3DSA:1.10.1740.10 19 117 7.8E-21 T 06-07-2017 LK06_RS17305 35d0519f1d0daafe67e5de87c1c389fb 600 SUPERFAMILY SSF49785 461 598 3.95E-28 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS17305 35d0519f1d0daafe67e5de87c1c389fb 600 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 202 2.2E-17 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS17305 35d0519f1d0daafe67e5de87c1c389fb 600 Gene3D G3DSA:1.10.10.10 143 202 4.2E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17305 35d0519f1d0daafe67e5de87c1c389fb 600 SUPERFAMILY SSF88659 140 201 6.17E-7 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS17305 35d0519f1d0daafe67e5de87c1c389fb 600 SMART SM00776 454 599 4.2E-37 T 06-07-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module LK06_RS17305 35d0519f1d0daafe67e5de87c1c389fb 600 Pfam PF04542 Sigma-70 region 2 38 106 4.9E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS17305 35d0519f1d0daafe67e5de87c1c389fb 600 SUPERFAMILY SSF88946 18 115 9.81E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20235 a1621f028772723c0dfbd26444f443ef 264 SUPERFAMILY SSF53639 27 246 2.75E-67 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal LK06_RS20235 a1621f028772723c0dfbd26444f443ef 264 SMART SM01007 35 215 2.5E-55 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal LK06_RS20235 a1621f028772723c0dfbd26444f443ef 264 Gene3D G3DSA:3.40.225.10 29 239 3.3E-63 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal LK06_RS20235 a1621f028772723c0dfbd26444f443ef 264 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 36 215 8.7E-47 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal LK06_RS11705 2502f7d935bc36088a05e38b3e009572 1647 Gene3D G3DSA:3.40.50.720 979 1090 1.1E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11705 2502f7d935bc36088a05e38b3e009572 1647 Gene3D G3DSA:3.40.50.720 1147 1247 1.1E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11705 2502f7d935bc36088a05e38b3e009572 1647 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 92 1640 0.0 T 06-07-2017 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 LK06_RS11705 2502f7d935bc36088a05e38b3e009572 1647 SUPERFAMILY SSF53223 791 977 6.43E-23 T 06-07-2017 LK06_RS11705 2502f7d935bc36088a05e38b3e009572 1647 SUPERFAMILY SSF51735 1122 1320 1.97E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11705 2502f7d935bc36088a05e38b3e009572 1647 SUPERFAMILY SSF51735 982 1084 1.97E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11705 2502f7d935bc36088a05e38b3e009572 1647 PIRSF PIRSF036761 7 1647 0.0 T 06-07-2017 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 LK06_RS31680 592717d42f390620471eade5140a2597 194 Gene3D G3DSA:1.10.357.10 3 190 9.0E-41 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS31680 592717d42f390620471eade5140a2597 194 SUPERFAMILY SSF48498 81 192 2.31E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS31680 592717d42f390620471eade5140a2597 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS31680 592717d42f390620471eade5140a2597 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS31680 592717d42f390620471eade5140a2597 194 SUPERFAMILY SSF46689 1 85 7.18E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS31680 592717d42f390620471eade5140a2597 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.1E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS31680 592717d42f390620471eade5140a2597 194 Pfam PF13977 Bacterial transcriptional repressor 84 177 9.0E-8 T 06-07-2017 LK06_RS14485 b3075ec359b582e1c50c5b6096bea599 350 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 346 3.3E-112 T 06-07-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS14485 b3075ec359b582e1c50c5b6096bea599 350 Gene3D G3DSA:3.40.50.720 4 143 3.1E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS14485 b3075ec359b582e1c50c5b6096bea599 350 PIRSF PIRSF000148 4 350 3.2E-113 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS14485 b3075ec359b582e1c50c5b6096bea599 350 SMART SM00859 6 121 5.0E-34 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LK06_RS14485 b3075ec359b582e1c50c5b6096bea599 350 Gene3D G3DSA:3.30.360.10 144 328 2.6E-68 T 06-07-2017 LK06_RS14485 b3075ec359b582e1c50c5b6096bea599 350 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 120 1.1E-28 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LK06_RS14485 b3075ec359b582e1c50c5b6096bea599 350 SUPERFAMILY SSF51735 7 158 3.79E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS14485 b3075ec359b582e1c50c5b6096bea599 350 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 140 332 2.0E-42 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS14485 b3075ec359b582e1c50c5b6096bea599 350 SUPERFAMILY SSF55347 131 333 2.33E-61 T 06-07-2017 LK06_RS14485 b3075ec359b582e1c50c5b6096bea599 350 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 346 32.132 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS26160 1793aa96193abaacf9bd330e14d1b273 390 SUPERFAMILY SSF103473 10 385 6.8E-35 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS26160 1793aa96193abaacf9bd330e14d1b273 390 Gene3D G3DSA:1.20.1250.20 211 383 6.4E-10 T 06-07-2017 LK06_RS26160 1793aa96193abaacf9bd330e14d1b273 390 Gene3D G3DSA:1.20.1250.20 13 180 4.9E-14 T 06-07-2017 LK06_RS26160 1793aa96193abaacf9bd330e14d1b273 390 Pfam PF07690 Major Facilitator Superfamily 17 326 3.2E-19 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS05105 dcc2262aa6b3edf158a103a3027827fc 264 Gene3D G3DSA:1.20.1080.10 6 262 4.7E-78 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 LK06_RS05105 dcc2262aa6b3edf158a103a3027827fc 264 ProSitePatterns PS00221 MIP family signature. 65 73 - T 06-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS05105 dcc2262aa6b3edf158a103a3027827fc 264 Pfam PF00230 Major intrinsic protein 6 259 9.4E-43 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS05105 dcc2262aa6b3edf158a103a3027827fc 264 SUPERFAMILY SSF81338 7 263 4.19E-60 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 LK06_RS05105 dcc2262aa6b3edf158a103a3027827fc 264 PRINTS PR00783 Major intrinsic protein family signature 195 217 4.5E-44 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS05105 dcc2262aa6b3edf158a103a3027827fc 264 PRINTS PR00783 Major intrinsic protein family signature 83 102 4.5E-44 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS05105 dcc2262aa6b3edf158a103a3027827fc 264 PRINTS PR00783 Major intrinsic protein family signature 5 24 4.5E-44 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS05105 dcc2262aa6b3edf158a103a3027827fc 264 PRINTS PR00783 Major intrinsic protein family signature 47 71 4.5E-44 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS05105 dcc2262aa6b3edf158a103a3027827fc 264 PRINTS PR00783 Major intrinsic protein family signature 162 180 4.5E-44 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS05105 dcc2262aa6b3edf158a103a3027827fc 264 PRINTS PR00783 Major intrinsic protein family signature 242 262 4.5E-44 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS32005 8e4068173e2791f3d14d9d5ee76651c5 129 Pfam PF05025 RbsD / FucU transport protein family 2 127 3.2E-39 T 06-07-2017 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 LK06_RS32005 8e4068173e2791f3d14d9d5ee76651c5 129 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 129 29.277 T 06-07-2017 IPR023064 D-ribose pyranase GO:0016872 LK06_RS32005 8e4068173e2791f3d14d9d5ee76651c5 129 SUPERFAMILY SSF102546 2 129 1.96E-37 T 06-07-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 LK06_RS32005 8e4068173e2791f3d14d9d5ee76651c5 129 Gene3D G3DSA:3.40.1650.10 2 129 1.4E-25 T 06-07-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 350 366 5.6E-40 T 06-07-2017 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 350 5.6E-40 T 06-07-2017 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 5.6E-40 T 06-07-2017 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 5.6E-40 T 06-07-2017 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 314 5.6E-40 T 06-07-2017 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 330 5.6E-40 T 06-07-2017 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 SUPERFAMILY SSF51905 9 190 7.57E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 SUPERFAMILY SSF51905 286 368 7.57E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 Gene3D G3DSA:3.50.50.60 111 195 9.3E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 Gene3D G3DSA:3.50.50.60 9 74 9.3E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 Gene3D G3DSA:3.50.50.60 287 363 9.3E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07925 5f4c4ac47bab8703531853965cfff6a7 549 Pfam PF01494 FAD binding domain 9 362 1.8E-107 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS05060 dc407bfeba61c06b81e9bb1ec8a4836c 558 Pfam PF02163 Peptidase family M50 315 364 6.0E-8 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 LK06_RS05060 dc407bfeba61c06b81e9bb1ec8a4836c 558 Gene3D G3DSA:3.10.580.10 435 552 1.4E-10 T 06-07-2017 LK06_RS05060 dc407bfeba61c06b81e9bb1ec8a4836c 558 SUPERFAMILY SSF54631 435 552 2.44E-10 T 06-07-2017 LK06_RS31280 0b316a477cb919dab6b89ed21128af50 337 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 151 4.9E-14 T 06-07-2017 IPR016188 PurM-like, N-terminal domain LK06_RS31280 0b316a477cb919dab6b89ed21128af50 337 PIRSF PIRSF005644 3 337 8.2E-117 T 06-07-2017 IPR011854 Hydrogenase expression/formation protein HypE LK06_RS31280 0b316a477cb919dab6b89ed21128af50 337 Gene3D G3DSA:3.90.650.10 160 316 5.1E-26 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS31280 0b316a477cb919dab6b89ed21128af50 337 Gene3D G3DSA:3.30.1330.10 20 153 1.1E-21 T 06-07-2017 IPR016188 PurM-like, N-terminal domain LK06_RS31280 0b316a477cb919dab6b89ed21128af50 337 SUPERFAMILY SSF55326 9 154 2.44E-27 T 06-07-2017 LK06_RS31280 0b316a477cb919dab6b89ed21128af50 337 Pfam PF02769 AIR synthase related protein, C-terminal domain 163 309 9.7E-27 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS31280 0b316a477cb919dab6b89ed21128af50 337 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 7 337 6.8E-131 T 06-07-2017 IPR011854 Hydrogenase expression/formation protein HypE LK06_RS31280 0b316a477cb919dab6b89ed21128af50 337 SUPERFAMILY SSF56042 157 333 1.5E-47 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS22755 ecfe4f55ddc08d1e9649e6b0a2ab8869 494 SUPERFAMILY SSF56601 147 492 1.25E-78 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS22755 ecfe4f55ddc08d1e9649e6b0a2ab8869 494 Pfam PF00905 Penicillin binding protein transpeptidase domain 164 488 9.4E-56 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS22755 ecfe4f55ddc08d1e9649e6b0a2ab8869 494 Gene3D G3DSA:3.40.710.10 152 492 2.4E-86 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS22755 ecfe4f55ddc08d1e9649e6b0a2ab8869 494 Gene3D G3DSA:3.90.1310.10 82 151 9.0E-4 T 06-07-2017 LK06_RS03595 0195b36ffe0ff79144a5dd02666b74bf 286 Gene3D G3DSA:1.10.3720.10 39 275 2.6E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS03595 0195b36ffe0ff79144a5dd02666b74bf 286 SUPERFAMILY SSF161098 32 277 2.88E-55 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS03595 0195b36ffe0ff79144a5dd02666b74bf 286 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 77 279 4.2E-74 T 06-07-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 LK06_RS03595 0195b36ffe0ff79144a5dd02666b74bf 286 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 54 274 1.6E-75 T 06-07-2017 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 LK06_RS03595 0195b36ffe0ff79144a5dd02666b74bf 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 275 8.2E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24045 2efb363f8a70510f9e72d4b70eaf53a2 346 SUPERFAMILY SSF55909 2 345 2.32E-118 T 06-07-2017 LK06_RS24045 2efb363f8a70510f9e72d4b70eaf53a2 346 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 10 344 7.8E-106 T 06-07-2017 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 LK06_RS24045 2efb363f8a70510f9e72d4b70eaf53a2 346 Hamap MF_01841 Agmatine deiminase [aguA]. 2 345 50.37 T 06-07-2017 IPR017754 Agmatine deiminase GO:0009446|GO:0047632 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 LK06_RS24045 2efb363f8a70510f9e72d4b70eaf53a2 346 Gene3D G3DSA:3.75.10.10 2 345 4.7E-119 T 06-07-2017 LK06_RS14610 93bc15b7b25c7e7ca31006fcdddf66ee 343 Gene3D G3DSA:3.20.20.70 2 340 5.9E-118 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS14610 93bc15b7b25c7e7ca31006fcdddf66ee 343 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 339 2.1E-79 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LK06_RS14610 93bc15b7b25c7e7ca31006fcdddf66ee 343 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 339 9.5E-130 T 06-07-2017 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 LK06_RS14610 93bc15b7b25c7e7ca31006fcdddf66ee 343 PIRSF PIRSF001359 5 341 2.4E-63 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LK06_RS14610 93bc15b7b25c7e7ca31006fcdddf66ee 343 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 9 340 3.3E-70 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LK06_RS14610 93bc15b7b25c7e7ca31006fcdddf66ee 343 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LK06_RS14610 93bc15b7b25c7e7ca31006fcdddf66ee 343 SUPERFAMILY SSF51569 4 339 3.81E-96 T 06-07-2017 LK06_RS10115 2da2f3a865230fea14db48d6b3c8f193 447 Gene3D G3DSA:3.40.190.10 161 339 6.1E-34 T 06-07-2017 LK06_RS10115 2da2f3a865230fea14db48d6b3c8f193 447 Pfam PF01547 Bacterial extracellular solute-binding protein 54 353 1.8E-31 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 LK06_RS10115 2da2f3a865230fea14db48d6b3c8f193 447 Gene3D G3DSA:3.40.190.10 44 160 9.5E-34 T 06-07-2017 LK06_RS10115 2da2f3a865230fea14db48d6b3c8f193 447 Gene3D G3DSA:3.40.190.10 340 394 9.5E-34 T 06-07-2017 LK06_RS10115 2da2f3a865230fea14db48d6b3c8f193 447 SUPERFAMILY SSF53850 40 440 4.44E-60 T 06-07-2017 LK06_RS11545 eba4613c05fd8b6bc714468fc79d88c7 325 Pfam PF03466 LysR substrate binding domain 111 297 5.1E-11 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS11545 eba4613c05fd8b6bc714468fc79d88c7 325 SUPERFAMILY SSF46785 8 89 1.36E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11545 eba4613c05fd8b6bc714468fc79d88c7 325 SUPERFAMILY SSF53850 110 301 2.79E-14 T 06-07-2017 LK06_RS11545 eba4613c05fd8b6bc714468fc79d88c7 325 Gene3D G3DSA:3.40.190.10 110 182 5.0E-10 T 06-07-2017 LK06_RS11545 eba4613c05fd8b6bc714468fc79d88c7 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 2.1E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS11545 eba4613c05fd8b6bc714468fc79d88c7 325 Gene3D G3DSA:3.40.190.10 183 224 6.6E-5 T 06-07-2017 LK06_RS11545 eba4613c05fd8b6bc714468fc79d88c7 325 Gene3D G3DSA:1.10.10.10 7 86 9.2E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11545 eba4613c05fd8b6bc714468fc79d88c7 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.4E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS11545 eba4613c05fd8b6bc714468fc79d88c7 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.4E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS11545 eba4613c05fd8b6bc714468fc79d88c7 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.4E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS12270 5c7d63d2d1a5107150479a863a3d2e5c 94 Pfam PF00366 Ribosomal protein S17 21 88 1.6E-30 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12270 5c7d63d2d1a5107150479a863a3d2e5c 94 PRINTS PR00973 Ribosomal protein S17 family signature 35 58 1.3E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12270 5c7d63d2d1a5107150479a863a3d2e5c 94 PRINTS PR00973 Ribosomal protein S17 family signature 77 84 1.3E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12270 5c7d63d2d1a5107150479a863a3d2e5c 94 PRINTS PR00973 Ribosomal protein S17 family signature 67 77 1.3E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12270 5c7d63d2d1a5107150479a863a3d2e5c 94 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 16 87 1.1E-34 T 06-07-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12270 5c7d63d2d1a5107150479a863a3d2e5c 94 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 21 87 2.0E-32 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12270 5c7d63d2d1a5107150479a863a3d2e5c 94 Gene3D G3DSA:2.40.50.140 16 93 1.0E-34 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS12270 5c7d63d2d1a5107150479a863a3d2e5c 94 ProSitePatterns PS00056 Ribosomal protein S17 signature. 67 79 - T 06-07-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12270 5c7d63d2d1a5107150479a863a3d2e5c 94 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 14 92 25.108 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12270 5c7d63d2d1a5107150479a863a3d2e5c 94 SUPERFAMILY SSF50249 16 93 2.06E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS08105 f49db659348620cd5468a7711ab13676 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 293 1.4E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS08105 f49db659348620cd5468a7711ab13676 301 Gene3D G3DSA:1.10.3720.10 24 288 4.5E-63 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS08105 f49db659348620cd5468a7711ab13676 301 SUPERFAMILY SSF161098 29 301 8.24E-65 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS28880 0a8d0f93692b4dcc11ef312d2689af88 435 Pfam PF07690 Major Facilitator Superfamily 59 290 9.8E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS28880 0a8d0f93692b4dcc11ef312d2689af88 435 Gene3D G3DSA:1.20.1250.20 17 204 1.1E-8 T 06-07-2017 LK06_RS28880 0a8d0f93692b4dcc11ef312d2689af88 435 Gene3D G3DSA:1.20.1250.20 240 410 9.2E-7 T 06-07-2017 LK06_RS28880 0a8d0f93692b4dcc11ef312d2689af88 435 SUPERFAMILY SSF103473 17 411 1.4E-22 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS03415 a1860610e52b1bee5a1c79f1e77abe0b 339 SUPERFAMILY SSF52540 90 120 3.14E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03415 a1860610e52b1bee5a1c79f1e77abe0b 339 SUPERFAMILY SSF52540 147 323 3.14E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03415 a1860610e52b1bee5a1c79f1e77abe0b 339 Gene3D G3DSA:3.40.50.300 88 227 3.0E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03415 a1860610e52b1bee5a1c79f1e77abe0b 339 Pfam PF05621 Bacterial TniB protein 82 317 7.1E-30 T 06-07-2017 IPR008868 Bacterial TniB LK06_RS23730 c534a434bd4e66f7af2c1948571d5c40 507 SUPERFAMILY SSF54001 67 175 1.47E-12 T 06-07-2017 LK06_RS23730 c534a434bd4e66f7af2c1948571d5c40 507 Gene3D G3DSA:2.120.10.70 221 490 5.2E-8 T 06-07-2017 LK06_RS23730 c534a434bd4e66f7af2c1948571d5c40 507 SUPERFAMILY SSF50978 186 475 1.83E-8 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 LK06_RS23730 c534a434bd4e66f7af2c1948571d5c40 507 Pfam PF05257 CHAP domain 71 147 2.8E-8 T 06-07-2017 IPR007921 CHAP domain LK06_RS11105 c8b79894017bf579dc0843771d9249e4 200 Gene3D G3DSA:3.90.950.10 1 198 6.0E-80 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like LK06_RS11105 c8b79894017bf579dc0843771d9249e4 200 SUPERFAMILY SSF52972 1 196 7.85E-66 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like LK06_RS11105 c8b79894017bf579dc0843771d9249e4 200 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 197 46.974 T 06-07-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 LK06_RS11105 c8b79894017bf579dc0843771d9249e4 200 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 192 8.1E-53 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 LK06_RS11105 c8b79894017bf579dc0843771d9249e4 200 Pfam PF01725 Ham1 family 4 192 9.6E-54 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 LK06_RS12170 b9e3a34e21d27338edca026b82c9be32 164 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 117 2.9E-41 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12170 b9e3a34e21d27338edca026b82c9be32 164 Gene3D G3DSA:3.90.1030.10 3 117 4.6E-47 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12170 b9e3a34e21d27338edca026b82c9be32 164 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12170 b9e3a34e21d27338edca026b82c9be32 164 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.489 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12170 b9e3a34e21d27338edca026b82c9be32 164 Pfam PF01196 Ribosomal protein L17 20 116 8.1E-38 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12170 b9e3a34e21d27338edca026b82c9be32 164 SUPERFAMILY SSF64263 1 117 4.84E-47 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS13700 056326333846696a446dedb2552be4f4 586 Gene3D G3DSA:4.10.80.40 525 546 1.1E-7 T 06-07-2017 LK06_RS13700 056326333846696a446dedb2552be4f4 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 4.3E-11 T 06-07-2017 LK06_RS13700 056326333846696a446dedb2552be4f4 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 362 384 4.3E-11 T 06-07-2017 LK06_RS13700 056326333846696a446dedb2552be4f4 586 SUPERFAMILY SSF51905 5 271 4.58E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13700 056326333846696a446dedb2552be4f4 586 SUPERFAMILY SSF51905 363 429 4.58E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13700 056326333846696a446dedb2552be4f4 586 Gene3D G3DSA:1.20.58.100 440 524 3.8E-22 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS13700 056326333846696a446dedb2552be4f4 586 Gene3D G3DSA:3.50.50.60 356 415 3.3E-97 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13700 056326333846696a446dedb2552be4f4 586 Gene3D G3DSA:3.50.50.60 14 247 3.3E-97 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13700 056326333846696a446dedb2552be4f4 586 Gene3D G3DSA:3.90.700.10 248 355 1.0E-35 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS13700 056326333846696a446dedb2552be4f4 586 SUPERFAMILY SSF46977 443 549 3.01E-31 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS13700 056326333846696a446dedb2552be4f4 586 PIRSF PIRSF000171 15 559 3.1E-41 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS13700 056326333846696a446dedb2552be4f4 586 Pfam PF02910 Fumarate reductase flavoprotein C-term 448 548 1.0E-21 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS13700 056326333846696a446dedb2552be4f4 586 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 19 530 2.6E-167 T 06-07-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 LK06_RS13700 056326333846696a446dedb2552be4f4 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 384 5.0E-6 T 06-07-2017 LK06_RS13700 056326333846696a446dedb2552be4f4 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 20 42 5.0E-6 T 06-07-2017 LK06_RS13700 056326333846696a446dedb2552be4f4 586 Pfam PF00890 FAD binding domain 20 399 2.5E-97 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS13700 056326333846696a446dedb2552be4f4 586 SUPERFAMILY SSF56425 242 359 1.79E-37 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20135 f02b0a5e53c5554383b6749a8f1e579b 222 Gene3D G3DSA:2.40.33.20 2 219 5.0E-72 T 06-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like LK06_RS20135 f02b0a5e53c5554383b6749a8f1e579b 222 SUPERFAMILY SSF50800 2 201 1.83E-55 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain LK06_RS20135 f02b0a5e53c5554383b6749a8f1e579b 222 Pfam PF03473 MOSC domain 57 170 6.4E-24 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 LK06_RS01900 b8dbee7a77b4879ca25566441e21c473 446 Pfam PF00348 Polyprenyl synthetase 96 344 1.4E-42 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS01900 b8dbee7a77b4879ca25566441e21c473 446 Gene3D G3DSA:1.10.600.10 91 415 2.0E-67 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS01900 b8dbee7a77b4879ca25566441e21c473 446 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 147 161 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS01900 b8dbee7a77b4879ca25566441e21c473 446 SUPERFAMILY SSF48576 90 407 1.11E-62 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS10740 0f28ae6aad02ad12a0e58f8699255ec1 292 Gene3D G3DSA:2.40.30.10 6 151 8.9E-31 T 06-07-2017 LK06_RS10740 0f28ae6aad02ad12a0e58f8699255ec1 292 Pfam PF08021 Siderophore-interacting FAD-binding domain 15 153 2.8E-38 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting LK06_RS10740 0f28ae6aad02ad12a0e58f8699255ec1 292 Gene3D G3DSA:3.40.50.80 161 290 2.2E-46 T 06-07-2017 LK06_RS10740 0f28ae6aad02ad12a0e58f8699255ec1 292 Pfam PF04954 Siderophore-interacting protein 168 282 1.3E-37 T 06-07-2017 IPR007037 Siderophore-interacting protein LK06_RS10740 0f28ae6aad02ad12a0e58f8699255ec1 292 SUPERFAMILY SSF63380 3 150 2.43E-9 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS27675 19bf47a7ecddeda4a606892dc0cb2a77 355 SUPERFAMILY SSF50129 3 172 1.51E-26 T 06-07-2017 IPR011032 GroES-like LK06_RS27675 19bf47a7ecddeda4a606892dc0cb2a77 355 Gene3D G3DSA:3.40.50.720 173 285 2.2E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27675 19bf47a7ecddeda4a606892dc0cb2a77 355 Gene3D G3DSA:3.90.180.10 2 172 1.0E-25 T 06-07-2017 IPR011032 GroES-like LK06_RS27675 19bf47a7ecddeda4a606892dc0cb2a77 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 88 1.6E-11 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS27675 19bf47a7ecddeda4a606892dc0cb2a77 355 SUPERFAMILY SSF51735 141 310 2.91E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08560 8f0efac8ce6c19155ab62943c838b5fa 483 Gene3D G3DSA:3.40.309.10 267 443 3.9E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS08560 8f0efac8ce6c19155ab62943c838b5fa 483 Pfam PF00171 Aldehyde dehydrogenase family 21 476 2.0E-150 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS08560 8f0efac8ce6c19155ab62943c838b5fa 483 SUPERFAMILY SSF53720 5 479 1.11E-154 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS08560 8f0efac8ce6c19155ab62943c838b5fa 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 LK06_RS08560 8f0efac8ce6c19155ab62943c838b5fa 483 Gene3D G3DSA:3.40.605.10 9 266 9.1E-82 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS06565 52923c069d127d5d6cca2631edf90d17 449 SUPERFAMILY SSF161098 302 434 1.31E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06565 52923c069d127d5d6cca2631edf90d17 449 SUPERFAMILY SSF161098 70 159 1.31E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06565 52923c069d127d5d6cca2631edf90d17 449 Pfam PF13620 Carboxypeptidase regulatory-like domain 248 302 2.6E-8 T 06-07-2017 LK06_RS06565 52923c069d127d5d6cca2631edf90d17 449 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 305 439 6.0E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06565 52923c069d127d5d6cca2631edf90d17 449 SUPERFAMILY SSF117074 219 294 3.01E-11 T 06-07-2017 LK06_RS06565 52923c069d127d5d6cca2631edf90d17 449 SUPERFAMILY SSF160964 30 71 9.81E-5 T 06-07-2017 LK06_RS06565 52923c069d127d5d6cca2631edf90d17 449 Gene3D G3DSA:2.60.40.10 244 299 1.8E-15 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS06565 52923c069d127d5d6cca2631edf90d17 449 Gene3D G3DSA:1.10.3720.10 304 440 1.3E-61 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06565 52923c069d127d5d6cca2631edf90d17 449 Gene3D G3DSA:1.10.3720.10 22 152 1.3E-61 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26680 dce94245bee9dad4778a61493190e690 244 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 156 242 7.3E-8 T 06-07-2017 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 LK06_RS26680 dce94245bee9dad4778a61493190e690 244 Gene3D G3DSA:3.40.1490.10 150 242 6.9E-17 T 06-07-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 LK06_RS26680 dce94245bee9dad4778a61493190e690 244 SUPERFAMILY SSF102462 151 241 9.59E-21 T 06-07-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 LK06_RS07495 05a354d9a487ba7bbb0ca161a38cda07 414 Pfam PF07730 Histidine kinase 190 237 2.6E-6 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS07495 05a354d9a487ba7bbb0ca161a38cda07 414 SUPERFAMILY SSF55874 301 400 1.57E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS07495 05a354d9a487ba7bbb0ca161a38cda07 414 Gene3D G3DSA:3.30.565.10 304 401 4.9E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS07495 05a354d9a487ba7bbb0ca161a38cda07 414 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 401 8.8E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16440 bc09f95a4f5f63f8d0426573b5ec3594 69 Pfam PF12728 Helix-turn-helix domain 4 51 3.3E-10 T 06-07-2017 LK06_RS16440 bc09f95a4f5f63f8d0426573b5ec3594 69 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 2.7E-18 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 7.1E-78 T 06-07-2017 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 Pfam PF00406 Adenylate kinase 5 191 1.5E-60 T 06-07-2017 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 PRINTS PR00094 Adenylate kinase signature 4 17 6.0E-36 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 PRINTS PR00094 Adenylate kinase signature 161 176 6.0E-36 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 PRINTS PR00094 Adenylate kinase signature 81 97 6.0E-36 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 PRINTS PR00094 Adenylate kinase signature 178 192 6.0E-36 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 PRINTS PR00094 Adenylate kinase signature 32 46 6.0E-36 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 Pfam PF05191 Adenylate kinase, active site lid 127 163 2.2E-12 T 06-07-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 Hamap MF_00235 Adenylate kinase [adk]. 1 214 52.333 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 06-07-2017 LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 Gene3D G3DSA:3.40.50.300 1 212 9.5E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12205 bdd8c4ce4c43045ecefe536f67bef98a 220 SUPERFAMILY SSF52540 1 215 1.61E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 10 846 0.0 T 06-07-2017 IPR024028 Polynucleotide kinase-phosphatase, bacterial LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 Gene3D G3DSA:3.60.21.10 184 421 5.7E-51 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 SUPERFAMILY SSF52540 17 171 4.57E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 788 846 4.3E-32 T 06-07-2017 IPR032390 Polynucleotide kinase-phosphatase, C-terminal LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 463 783 1.3E-143 T 06-07-2017 IPR032380 Polynucleotide kinase-phosphatase, ligase domain LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 Pfam PF00149 Calcineurin-like phosphoesterase 189 375 1.3E-12 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 SUPERFAMILY SSF56091 465 602 1.26E-11 T 06-07-2017 LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 SUPERFAMILY SSF56091 671 754 1.26E-11 T 06-07-2017 LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 Gene3D G3DSA:3.40.50.300 17 145 2.9E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 SUPERFAMILY SSF56300 118 399 3.28E-45 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS26050 7bc4fe94b97b22585e51f06e25036a94 846 Pfam PF13671 AAA domain 17 147 1.2E-24 T 06-07-2017 LK06_RS13430 56dc51591ddc20cf076306f553339a70 254 Gene3D G3DSA:3.40.50.720 88 221 3.7E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13430 56dc51591ddc20cf076306f553339a70 254 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 11 219 36.744 T 06-07-2017 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 LK06_RS13430 56dc51591ddc20cf076306f553339a70 254 SUPERFAMILY SSF51735 93 214 1.97E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13430 56dc51591ddc20cf076306f553339a70 254 Pfam PF02629 CoA binding domain 91 188 1.2E-21 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS13430 56dc51591ddc20cf076306f553339a70 254 Gene3D G3DSA:1.10.10.10 15 85 2.3E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13430 56dc51591ddc20cf076306f553339a70 254 Pfam PF06971 Putative DNA-binding protein N-terminus 16 63 3.7E-19 T 06-07-2017 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 LK06_RS13430 56dc51591ddc20cf076306f553339a70 254 SMART SM00881 89 190 7.7E-18 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS13430 56dc51591ddc20cf076306f553339a70 254 SUPERFAMILY SSF46785 17 89 1.25E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12240 3cea1ee0da1753ed774cb57dedae7fdf 132 Gene3D G3DSA:3.30.1490.10 76 132 7.5E-29 T 06-07-2017 LK06_RS12240 3cea1ee0da1753ed774cb57dedae7fdf 132 SUPERFAMILY SSF56047 3 132 3.4E-44 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12240 3cea1ee0da1753ed774cb57dedae7fdf 132 Pfam PF00410 Ribosomal protein S8 5 132 1.0E-49 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12240 3cea1ee0da1753ed774cb57dedae7fdf 132 Gene3D G3DSA:3.30.1370.30 2 72 6.6E-28 T 06-07-2017 LK06_RS12240 3cea1ee0da1753ed774cb57dedae7fdf 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.869 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12620 eee6f2cc63520a5e9c1c5159267ef5eb 418 Pfam PF13520 Amino acid permease 12 389 2.0E-38 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS12620 eee6f2cc63520a5e9c1c5159267ef5eb 418 PIRSF PIRSF006060 1 413 4.7E-67 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS27135 93628a6cbe904322a4d04e3390337043 198 SUPERFAMILY SSF47741 120 193 2.36E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LK06_RS27135 93628a6cbe904322a4d04e3390337043 198 Gene3D G3DSA:1.10.150.120 120 195 4.0E-33 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LK06_RS27135 93628a6cbe904322a4d04e3390337043 198 Pfam PF01799 [2Fe-2S] binding domain 121 187 5.2E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LK06_RS27135 93628a6cbe904322a4d04e3390337043 198 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 53 2.6E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS27135 93628a6cbe904322a4d04e3390337043 198 SUPERFAMILY SSF54292 2 79 4.06E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS27135 93628a6cbe904322a4d04e3390337043 198 Gene3D G3DSA:3.10.20.30 2 77 5.5E-27 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS27135 93628a6cbe904322a4d04e3390337043 198 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LK06_RS06920 dfe6d78275e0e1f7e2df0953f0e3b5d4 238 SMART SM00382 29 216 6.6E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS06920 dfe6d78275e0e1f7e2df0953f0e3b5d4 238 Pfam PF00005 ABC transporter 21 165 5.3E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS06920 dfe6d78275e0e1f7e2df0953f0e3b5d4 238 SUPERFAMILY SSF52540 4 236 3.77E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06920 dfe6d78275e0e1f7e2df0953f0e3b5d4 238 Gene3D G3DSA:3.40.50.300 4 232 4.9E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06920 dfe6d78275e0e1f7e2df0953f0e3b5d4 238 PIRSF PIRSF039137 1 238 1.3E-111 T 06-07-2017 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 LK06_RS06920 dfe6d78275e0e1f7e2df0953f0e3b5d4 238 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS32235 e1dbb295147098ead2801e8f61c3934c 240 Gene3D G3DSA:3.40.1410.10 71 226 2.5E-21 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS32235 e1dbb295147098ead2801e8f61c3934c 240 SUPERFAMILY SSF64288 64 230 1.03E-19 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS32235 e1dbb295147098ead2801e8f61c3934c 240 SMART SM00345 10 68 7.7E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS32235 e1dbb295147098ead2801e8f61c3934c 240 SMART SM00866 93 233 1.6E-4 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS32235 e1dbb295147098ead2801e8f61c3934c 240 Pfam PF07702 UTRA domain 97 225 1.9E-13 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS32235 e1dbb295147098ead2801e8f61c3934c 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 67 6.5E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS32235 e1dbb295147098ead2801e8f61c3934c 240 Gene3D G3DSA:1.10.10.10 9 70 2.7E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32235 e1dbb295147098ead2801e8f61c3934c 240 SUPERFAMILY SSF46785 5 82 2.56E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 Gene3D G3DSA:3.40.50.920 468 586 2.9E-22 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 1 587 37.675 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 Gene3D G3DSA:3.40.50.970 8 264 2.6E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 Pfam PF02780 Transketolase, C-terminal domain 468 578 2.5E-17 T 06-07-2017 IPR033248 Transketolase, C-terminal domain LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 SUPERFAMILY SSF52518 19 328 9.47E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 SUPERFAMILY SSF52922 468 586 1.7E-19 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 Pfam PF02779 Transketolase, pyrimidine binding domain 281 443 6.8E-40 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 ProSitePatterns PS00801 Transketolase signature 1. 27 46 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 Gene3D G3DSA:3.40.50.970 265 443 1.2E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 SUPERFAMILY SSF52518 260 442 1.59E-53 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 SMART SM00861 281 445 4.7E-56 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 202 245 1.1E-9 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 7 194 2.3E-81 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS29460 810a0988dbca1f642cda9e73c4333b3b 605 ProSitePatterns PS00802 Transketolase signature 2. 387 403 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS26735 a954612cb41045da841761aceefa2200 464 Pfam PF01225 Mur ligase family, catalytic domain 13 109 4.5E-27 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LK06_RS26735 a954612cb41045da841761aceefa2200 464 Gene3D G3DSA:3.40.1190.10 99 316 3.5E-71 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS26735 a954612cb41045da841761aceefa2200 464 Pfam PF08245 Mur ligase middle domain 115 294 3.1E-22 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS26735 a954612cb41045da841761aceefa2200 464 SUPERFAMILY SSF53623 96 312 6.28E-56 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS26735 a954612cb41045da841761aceefa2200 464 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 401 5.2E-20 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS26735 a954612cb41045da841761aceefa2200 464 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 455 1.5E-137 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS26735 a954612cb41045da841761aceefa2200 464 Gene3D G3DSA:3.90.190.20 317 461 3.8E-49 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS26735 a954612cb41045da841761aceefa2200 464 Gene3D G3DSA:3.40.50.720 12 98 2.9E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26735 a954612cb41045da841761aceefa2200 464 SUPERFAMILY SSF51984 10 98 1.18E-26 T 06-07-2017 LK06_RS26735 a954612cb41045da841761aceefa2200 464 SUPERFAMILY SSF53244 314 459 2.93E-42 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS26735 a954612cb41045da841761aceefa2200 464 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 9 462 38.186 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS16125 f12e5c2eadc0da2b38f9921b6732a0e1 368 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 362 2.9E-87 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LK06_RS16125 f12e5c2eadc0da2b38f9921b6732a0e1 368 SUPERFAMILY SSF53383 29 360 2.18E-77 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS16125 f12e5c2eadc0da2b38f9921b6732a0e1 368 Pfam PF00155 Aminotransferase class I and II 42 356 3.3E-49 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS16125 f12e5c2eadc0da2b38f9921b6732a0e1 368 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 8 366 49.843 T 06-07-2017 IPR024892 Putative phenylalanine aminotransferase LK06_RS16125 f12e5c2eadc0da2b38f9921b6732a0e1 368 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 365 50.083 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LK06_RS16125 f12e5c2eadc0da2b38f9921b6732a0e1 368 Gene3D G3DSA:3.90.1150.10 255 363 1.8E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS16125 f12e5c2eadc0da2b38f9921b6732a0e1 368 Gene3D G3DSA:3.40.640.10 56 254 5.6E-44 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS16125 f12e5c2eadc0da2b38f9921b6732a0e1 368 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 229 238 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 LK06_RS06590 3910bc9b233b781ee40bd990369cb40d 249 Pfam PF00005 ABC transporter 29 176 6.1E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS06590 3910bc9b233b781ee40bd990369cb40d 249 SUPERFAMILY SSF52540 8 231 5.19E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06590 3910bc9b233b781ee40bd990369cb40d 249 Gene3D G3DSA:3.40.50.300 3 229 3.4E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06590 3910bc9b233b781ee40bd990369cb40d 249 SMART SM00382 37 224 3.5E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS06590 3910bc9b233b781ee40bd990369cb40d 249 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS15540 ae5d79f2d75e27337b9d79750d423685 245 Pfam PF03358 NADPH-dependent FMN reductase 21 171 1.9E-13 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 LK06_RS15540 ae5d79f2d75e27337b9d79750d423685 245 Gene3D G3DSA:3.40.50.360 20 175 9.6E-16 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS15540 ae5d79f2d75e27337b9d79750d423685 245 SUPERFAMILY SSF52218 20 212 5.99E-31 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS31495 1f1b3a30b3f8d17924b1ceeb2a44602e 250 SUPERFAMILY SSF47240 8 244 1.03E-71 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS31495 1f1b3a30b3f8d17924b1ceeb2a44602e 250 Pfam PF05138 Phenylacetic acid catabolic protein 7 250 2.1E-83 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 LK06_RS31495 1f1b3a30b3f8d17924b1ceeb2a44602e 250 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 12 250 2.4E-80 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 LK06_RS31495 1f1b3a30b3f8d17924b1ceeb2a44602e 250 PIRSF PIRSF037834 1 250 1.5E-90 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 LK06_RS31495 1f1b3a30b3f8d17924b1ceeb2a44602e 250 Gene3D G3DSA:1.20.1260.10 6 250 3.6E-88 T 06-07-2017 IPR012347 Ferritin-related LK06_RS03355 bf6b0ff1ba7c76392b94df3f9da58953 142 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 137 3.8E-21 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase LK06_RS03355 bf6b0ff1ba7c76392b94df3f9da58953 142 SUPERFAMILY SSF55961 1 140 2.95E-23 T 06-07-2017 LK06_RS03355 bf6b0ff1ba7c76392b94df3f9da58953 142 Gene3D G3DSA:3.30.530.20 1 141 8.1E-17 T 06-07-2017 IPR023393 START-like domain LK06_RS08700 826fe70028653a0ce3f6bc8d1d8568cf 299 Gene3D G3DSA:3.40.50.720 5 188 7.3E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08700 826fe70028653a0ce3f6bc8d1d8568cf 299 Gene3D G3DSA:1.10.1040.10 189 295 7.5E-24 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS08700 826fe70028653a0ce3f6bc8d1d8568cf 299 SUPERFAMILY SSF51735 4 125 5.01E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08700 826fe70028653a0ce3f6bc8d1d8568cf 299 SUPERFAMILY SSF48179 182 295 1.19E-20 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS08700 826fe70028653a0ce3f6bc8d1d8568cf 299 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 182 295 2.4E-16 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 LK06_RS08700 826fe70028653a0ce3f6bc8d1d8568cf 299 Pfam PF02558 Ketopantoate reductase PanE/ApbA 7 143 5.2E-24 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 LK06_RS08700 826fe70028653a0ce3f6bc8d1d8568cf 299 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 6 295 1.8E-50 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 LK06_RS28215 f8e7ed3c11153784388b9c274407a89f 608 Gene3D G3DSA:3.40.50.980 345 406 1.7E-25 T 06-07-2017 LK06_RS28215 f8e7ed3c11153784388b9c274407a89f 608 Gene3D G3DSA:3.40.50.980 190 289 1.7E-25 T 06-07-2017 LK06_RS28215 f8e7ed3c11153784388b9c274407a89f 608 Gene3D G3DSA:2.30.38.10 407 468 2.4E-18 T 06-07-2017 LK06_RS28215 f8e7ed3c11153784388b9c274407a89f 608 Pfam PF00501 AMP-binding enzyme 26 477 3.0E-90 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS28215 f8e7ed3c11153784388b9c274407a89f 608 SUPERFAMILY SSF56801 348 606 8.24E-111 T 06-07-2017 LK06_RS28215 f8e7ed3c11153784388b9c274407a89f 608 SUPERFAMILY SSF56801 18 294 8.24E-111 T 06-07-2017 LK06_RS28215 f8e7ed3c11153784388b9c274407a89f 608 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS28215 f8e7ed3c11153784388b9c274407a89f 608 Gene3D G3DSA:3.30.300.30 475 594 2.8E-6 T 06-07-2017 LK06_RS28215 f8e7ed3c11153784388b9c274407a89f 608 Gene3D G3DSA:3.40.50.980 19 189 1.5E-31 T 06-07-2017 LK06_RS03115 478d62419e0ef98bafdd4f7c92ac5752 303 Gene3D G3DSA:3.30.360.10 127 297 7.7E-57 T 06-07-2017 LK06_RS03115 478d62419e0ef98bafdd4f7c92ac5752 303 Gene3D G3DSA:3.40.50.720 1 126 7.5E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03115 478d62419e0ef98bafdd4f7c92ac5752 303 SUPERFAMILY SSF55347 123 258 1.9E-35 T 06-07-2017 LK06_RS03115 478d62419e0ef98bafdd4f7c92ac5752 303 SUPERFAMILY SSF51735 1 137 4.73E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03115 478d62419e0ef98bafdd4f7c92ac5752 303 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 121 1.8E-14 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 7 484 1.7E-131 T 06-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 68 119 2.0E-11 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 3.4E-50 T 06-07-2017 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 426 445 3.4E-50 T 06-07-2017 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 3.4E-50 T 06-07-2017 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 3.4E-50 T 06-07-2017 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 3.4E-50 T 06-07-2017 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 81 106 3.4E-50 T 06-07-2017 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 156 177 3.4E-50 T 06-07-2017 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 Pfam PF00361 Proton-conducting membrane transporter 132 403 1.2E-73 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 83 103 5.1E-6 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 261 283 5.1E-6 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LK06_RS12645 26e0e5ee1d8dc6e9f7c6ae68724e273d 664 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 425 447 5.1E-6 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LK06_RS27600 565ce9e298916e0dd5c68ac7a7d9e81d 958 SMART SM00487 492 669 4.0E-25 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS27600 565ce9e298916e0dd5c68ac7a7d9e81d 958 Gene3D G3DSA:3.40.50.300 784 933 4.0E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27600 565ce9e298916e0dd5c68ac7a7d9e81d 958 SUPERFAMILY SSF52540 708 955 1.46E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27600 565ce9e298916e0dd5c68ac7a7d9e81d 958 SUPERFAMILY SSF52540 484 700 3.07E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27600 565ce9e298916e0dd5c68ac7a7d9e81d 958 Pfam PF00176 SNF2 family N-terminal domain 515 770 1.9E-46 T 06-07-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 LK06_RS27600 565ce9e298916e0dd5c68ac7a7d9e81d 958 SMART SM00490 816 898 2.9E-23 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS27600 565ce9e298916e0dd5c68ac7a7d9e81d 958 Pfam PF00271 Helicase conserved C-terminal domain 787 898 6.2E-17 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS27600 565ce9e298916e0dd5c68ac7a7d9e81d 958 Gene3D G3DSA:3.40.50.300 490 655 4.0E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27600 565ce9e298916e0dd5c68ac7a7d9e81d 958 Pfam PF12419 SNF2 Helicase protein 324 452 7.1E-35 T 06-07-2017 IPR022138 Helicase SWF/SNF-related LK06_RS07915 7e08ded01143f6a1bb18c45d22cec303 147 PIRSF PIRSF016602 2 142 1.1E-55 T 06-07-2017 IPR016672 Polyketide biosynthesis protein CurC, predicted LK06_RS07915 7e08ded01143f6a1bb18c45d22cec303 147 Gene3D G3DSA:2.60.120.10 21 118 3.2E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS07915 7e08ded01143f6a1bb18c45d22cec303 147 Pfam PF07883 Cupin domain 42 108 1.2E-17 T 06-07-2017 IPR013096 Cupin 2, conserved barrel LK06_RS07915 7e08ded01143f6a1bb18c45d22cec303 147 SUPERFAMILY SSF51182 18 129 6.33E-25 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 Gene3D G3DSA:3.30.420.40 6 163 5.2E-45 T 06-07-2017 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 SUPERFAMILY SSF53067 6 316 1.3E-38 T 06-07-2017 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 06-07-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 321 3.7E-125 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 340 61.691 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 Pfam PF00814 Glycoprotease family 27 314 1.5E-96 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 314 4.2E-97 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 271 280 1.6E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 1.6E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 1.6E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 1.6E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 1.6E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS20085 37982217054f1f9d266f52aeb2cd4412 361 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 1.6E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 06-07-2017 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 Pfam PF08544 GHMP kinases C terminal 282 362 1.2E-12 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 Pfam PF10509 Galactokinase galactose-binding signature 8 56 1.7E-21 T 06-07-2017 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 Gene3D G3DSA:3.30.230.10 4 209 1.5E-73 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 PIRSF PIRSF000530 2 384 1.6E-126 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 Pfam PF00288 GHMP kinases N terminal domain 112 178 1.3E-15 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 Hamap MF_00246 Galactokinase [galK]. 24 382 42.119 T 06-07-2017 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 Gene3D G3DSA:3.30.70.890 210 381 7.8E-52 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 SUPERFAMILY SSF55060 205 382 1.08E-45 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 119 130 - T 06-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 PRINTS PR00959 Mevalonate kinase family signature 24 48 8.3E-40 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 PRINTS PR00959 Mevalonate kinase family signature 160 179 8.3E-40 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 PRINTS PR00959 Mevalonate kinase family signature 329 346 8.3E-40 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 PRINTS PR00959 Mevalonate kinase family signature 117 139 8.3E-40 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 TIGRFAM TIGR00131 gal_kin: galactokinase 4 361 1.5E-92 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 SUPERFAMILY SSF54211 4 200 2.2E-62 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 PRINTS PR00473 Galactokinase signature 110 128 9.8E-23 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 PRINTS PR00473 Galactokinase signature 90 101 9.8E-23 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 PRINTS PR00473 Galactokinase signature 26 44 9.8E-23 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS19755 65fe80447d3c3f5154da8435926c753d 384 PRINTS PR00473 Galactokinase signature 266 280 9.8E-23 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 5 477 49.824 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 Gene3D G3DSA:3.40.50.1480 406 485 6.7E-35 T 06-07-2017 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 243 405 4.0E-84 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 SMART SM00997 243 405 1.0E-112 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 Gene3D G3DSA:3.40.50.720 281 357 3.9E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 Gene3D G3DSA:3.40.50.1480 7 156 1.6E-125 T 06-07-2017 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 Gene3D G3DSA:3.40.50.1480 194 280 1.6E-125 T 06-07-2017 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 9 484 2.9E-148 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 SUPERFAMILY SSF52283 7 157 2.55E-114 T 06-07-2017 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 SUPERFAMILY SSF52283 406 485 2.55E-114 T 06-07-2017 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 SUPERFAMILY SSF52283 195 242 2.55E-114 T 06-07-2017 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 SUPERFAMILY SSF51735 243 405 1.78E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 10 477 1.3E-192 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 SMART SM00996 9 484 0.0 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 81 95 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 PIRSF PIRSF001109 1 485 1.8E-193 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LK06_RS11840 b760555f918f6785136bdbd6aec61058 485 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 265 281 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LK06_RS01020 43f34b53d303ac89567c37461da4d536 615 Gene3D G3DSA:3.40.50.300 379 603 1.5E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01020 43f34b53d303ac89567c37461da4d536 615 SMART SM00382 403 583 4.6E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS01020 43f34b53d303ac89567c37461da4d536 615 Gene3D G3DSA:1.20.1560.10 5 283 5.4E-13 T 06-07-2017 LK06_RS01020 43f34b53d303ac89567c37461da4d536 615 SUPERFAMILY SSF52540 376 603 2.3E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01020 43f34b53d303ac89567c37461da4d536 615 SUPERFAMILY SSF90123 5 288 4.19E-22 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS01020 43f34b53d303ac89567c37461da4d536 615 Pfam PF00005 ABC transporter 394 537 4.6E-17 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS04675 2dc50a78b44bda711587af1fd60752f5 445 SUPERFAMILY SSF63380 220 315 2.46E-14 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS04675 2dc50a78b44bda711587af1fd60752f5 445 Gene3D G3DSA:3.40.50.80 308 439 1.4E-27 T 06-07-2017 LK06_RS04675 2dc50a78b44bda711587af1fd60752f5 445 SUPERFAMILY SSF52343 307 441 9.69E-29 T 06-07-2017 LK06_RS04675 2dc50a78b44bda711587af1fd60752f5 445 Pfam PF00175 Oxidoreductase NAD-binding domain 328 424 2.4E-11 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LK06_RS04675 2dc50a78b44bda711587af1fd60752f5 445 PRINTS PR00410 Phenol hydroxylase reductase family signature 411 419 8.6E-7 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS04675 2dc50a78b44bda711587af1fd60752f5 445 PRINTS PR00410 Phenol hydroxylase reductase family signature 327 346 8.6E-7 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS04675 2dc50a78b44bda711587af1fd60752f5 445 PRINTS PR00410 Phenol hydroxylase reductase family signature 311 320 8.6E-7 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS04675 2dc50a78b44bda711587af1fd60752f5 445 Pfam PF01794 Ferric reductase like transmembrane component 50 175 4.1E-15 T 06-07-2017 IPR013130 Ferric reductase transmembrane component-like domain LK06_RS04675 2dc50a78b44bda711587af1fd60752f5 445 Gene3D G3DSA:2.40.30.10 222 307 4.3E-11 T 06-07-2017 LK06_RS16005 4bfe2cfdafde485a1c1c6319f108b52b 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 2.0E-21 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16005 4bfe2cfdafde485a1c1c6319f108b52b 148 SUPERFAMILY SSF55653 59 147 4.45E-25 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal LK06_RS16005 4bfe2cfdafde485a1c1c6319f108b52b 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16005 4bfe2cfdafde485a1c1c6319f108b52b 148 SUPERFAMILY SSF55658 1 56 1.12E-17 T 06-07-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal LK06_RS16005 4bfe2cfdafde485a1c1c6319f108b52b 148 Gene3D G3DSA:3.10.430.100 61 147 1.6E-29 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal LK06_RS16005 4bfe2cfdafde485a1c1c6319f108b52b 148 Gene3D G3DSA:3.40.5.10 1 51 1.3E-22 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16005 4bfe2cfdafde485a1c1c6319f108b52b 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 147 6.0E-28 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal LK06_RS16005 4bfe2cfdafde485a1c1c6319f108b52b 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 3.8E-40 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS16005 4bfe2cfdafde485a1c1c6319f108b52b 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.592 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS30395 321f26601bcae3a3750bba7fd71bdafd 389 SUPERFAMILY SSF56601 14 386 1.18E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS30395 321f26601bcae3a3750bba7fd71bdafd 389 Pfam PF00144 Beta-lactamase 25 371 7.9E-74 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS30395 321f26601bcae3a3750bba7fd71bdafd 389 Gene3D G3DSA:3.40.710.10 14 388 8.8E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS25145 cc8577233549000d761f5754f8ee3439 521 SUPERFAMILY SSF63737 56 247 1.31E-33 T 06-07-2017 LK06_RS25145 cc8577233549000d761f5754f8ee3439 521 Pfam PF01433 Peptidase family M1 73 393 8.0E-31 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS25145 cc8577233549000d761f5754f8ee3439 521 SUPERFAMILY SSF55486 257 492 4.54E-51 T 06-07-2017 LK06_RS25145 cc8577233549000d761f5754f8ee3439 521 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 184 199 1.1E-10 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS25145 cc8577233549000d761f5754f8ee3439 521 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 339 354 1.1E-10 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS25145 cc8577233549000d761f5754f8ee3439 521 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 358 370 1.1E-10 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS25145 cc8577233549000d761f5754f8ee3439 521 Gene3D G3DSA:1.10.390.10 353 493 2.5E-18 T 06-07-2017 LK06_RS20010 425664699c8dbe98ee1bf97246d813b2 76 Pfam PF14117 Domain of unknown function (DUF4287) 9 67 1.3E-23 T 06-07-2017 IPR025629 Protein of unknown function DUF4287 LK06_RS19730 c7aa826b2443df612a26b1b0a284fd60 230 Gene3D G3DSA:3.40.50.2300 2 153 8.1E-15 T 06-07-2017 LK06_RS19730 c7aa826b2443df612a26b1b0a284fd60 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 6.7E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS19730 c7aa826b2443df612a26b1b0a284fd60 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 6.7E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS19730 c7aa826b2443df612a26b1b0a284fd60 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 6.7E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS19730 c7aa826b2443df612a26b1b0a284fd60 230 SMART SM00421 153 210 2.4E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS19730 c7aa826b2443df612a26b1b0a284fd60 230 Gene3D G3DSA:1.10.10.10 154 215 7.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19730 c7aa826b2443df612a26b1b0a284fd60 230 SUPERFAMILY SSF52172 2 126 2.28E-12 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS19730 c7aa826b2443df612a26b1b0a284fd60 230 Pfam PF00072 Response regulator receiver domain 6 104 9.6E-8 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS19730 c7aa826b2443df612a26b1b0a284fd60 230 SUPERFAMILY SSF46894 139 217 2.55E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS19730 c7aa826b2443df612a26b1b0a284fd60 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.6E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26445 561abb67af2980614dc75a0dfc52f5fb 376 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 107 117 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site LK06_RS26445 561abb67af2980614dc75a0dfc52f5fb 376 PRINTS PR00723 Subtilisin serine protease family (S8) signature 103 116 8.6E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS26445 561abb67af2980614dc75a0dfc52f5fb 376 PRINTS PR00723 Subtilisin serine protease family (S8) signature 261 277 8.6E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS26445 561abb67af2980614dc75a0dfc52f5fb 376 PRINTS PR00723 Subtilisin serine protease family (S8) signature 62 81 8.6E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS26445 561abb67af2980614dc75a0dfc52f5fb 376 Pfam PF00082 Subtilase family 62 312 4.2E-43 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS26445 561abb67af2980614dc75a0dfc52f5fb 376 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 67 78 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site LK06_RS26445 561abb67af2980614dc75a0dfc52f5fb 376 SUPERFAMILY SSF52743 46 323 5.5E-75 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS26445 561abb67af2980614dc75a0dfc52f5fb 376 Gene3D G3DSA:3.40.50.200 42 323 4.0E-75 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS29900 f0decc762afc300b5d759109a43a4c95 192 SUPERFAMILY SSF46785 38 181 1.18E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29900 f0decc762afc300b5d759109a43a4c95 192 SMART SM00347 65 166 1.3E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29900 f0decc762afc300b5d759109a43a4c95 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 142 9.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29900 f0decc762afc300b5d759109a43a4c95 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 122 9.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29900 f0decc762afc300b5d759109a43a4c95 192 Pfam PF12802 MarR family 71 129 1.5E-14 T 06-07-2017 LK06_RS29900 f0decc762afc300b5d759109a43a4c95 192 Gene3D G3DSA:1.10.10.10 31 181 2.3E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 SUPERFAMILY SSF46946 139 228 2.21E-27 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 Gene3D G3DSA:3.20.190.10 2 129 1.1E-36 T 06-07-2017 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 139 226 1.1E-23 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 279 1.0E-88 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 SMART SM00898 2 123 4.1E-44 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 280 41.561 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 SMART SM01232 139 231 3.0E-42 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 Gene3D G3DSA:1.10.8.50 141 280 3.1E-47 T 06-07-2017 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 SUPERFAMILY SSF57716 231 280 1.51E-15 T 06-07-2017 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 SUPERFAMILY SSF81624 2 144 3.01E-34 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 121 2.7E-33 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS24300 157a09f79cbe7acb54d32115aabefba7 294 ProSitePatterns PS01242 Zinc finger FPG-type signature. 255 279 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 PRINTS PR00171 Sugar transporter signature 35 45 9.5E-22 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 PRINTS PR00171 Sugar transporter signature 378 399 9.5E-22 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 PRINTS PR00171 Sugar transporter signature 118 137 9.5E-22 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 PRINTS PR00171 Sugar transporter signature 285 295 9.5E-22 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 PRINTS PR00171 Sugar transporter signature 401 413 9.5E-22 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 ProSitePatterns PS00216 Sugar transport proteins signature 1. 329 346 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 Gene3D G3DSA:1.20.1250.20 273 471 3.1E-22 T 06-07-2017 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 Gene3D G3DSA:1.20.1250.20 31 225 1.2E-22 T 06-07-2017 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 Pfam PF00083 Sugar (and other) transporter 28 472 1.5E-104 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 11 472 1.0E-101 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 LK06_RS24350 95a00e78833594b2e1c1453c665a5091 473 SUPERFAMILY SSF103473 22 472 1.57E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS24275 a8376e88292ff770413790763e3af1de 169 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 12 167 35.322 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 LK06_RS24275 a8376e88292ff770413790763e3af1de 169 Gene3D G3DSA:3.40.50.620 12 165 1.6E-52 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS24275 a8376e88292ff770413790763e3af1de 169 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 21 131 1.0E-4 T 06-07-2017 LK06_RS24275 a8376e88292ff770413790763e3af1de 169 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 13 165 2.6E-60 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 LK06_RS24275 a8376e88292ff770413790763e3af1de 169 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 69 1.5E-15 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LK06_RS24275 a8376e88292ff770413790763e3af1de 169 Pfam PF01467 Cytidylyltransferase-like 16 142 1.3E-18 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LK06_RS24275 a8376e88292ff770413790763e3af1de 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 12 30 1.1E-51 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 LK06_RS24275 a8376e88292ff770413790763e3af1de 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 59 83 1.1E-51 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 LK06_RS24275 a8376e88292ff770413790763e3af1de 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 30 51 1.1E-51 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 LK06_RS24275 a8376e88292ff770413790763e3af1de 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 121 143 1.1E-51 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 LK06_RS24275 a8376e88292ff770413790763e3af1de 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 95 111 1.1E-51 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 LK06_RS24275 a8376e88292ff770413790763e3af1de 169 SUPERFAMILY SSF52374 12 164 2.39E-45 T 06-07-2017 LK06_RS28140 aaf03593c016429c936daf58b4d8eed4 257 Gene3D G3DSA:3.60.15.10 3 254 9.1E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS28140 aaf03593c016429c936daf58b4d8eed4 257 Pfam PF12706 Beta-lactamase superfamily domain 20 206 2.3E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS28140 aaf03593c016429c936daf58b4d8eed4 257 SUPERFAMILY SSF56281 3 74 3.22E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS28140 aaf03593c016429c936daf58b4d8eed4 257 SUPERFAMILY SSF56281 101 213 3.22E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS28910 9aaecac1562803cdbba505ab164f2577 467 Pfam PF00120 Glutamine synthetase, catalytic domain 126 449 1.7E-71 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS28910 9aaecac1562803cdbba505ab164f2577 467 SUPERFAMILY SSF54368 24 121 5.62E-5 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS28910 9aaecac1562803cdbba505ab164f2577 467 SMART SM01230 125 377 9.0E-75 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS28910 9aaecac1562803cdbba505ab164f2577 467 SUPERFAMILY SSF55931 125 453 9.81E-77 T 06-07-2017 LK06_RS28910 9aaecac1562803cdbba505ab164f2577 467 Gene3D G3DSA:3.10.20.70 26 126 6.9E-4 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS28910 9aaecac1562803cdbba505ab164f2577 467 Gene3D G3DSA:3.30.590.10 129 449 5.4E-82 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LK06_RS28910 9aaecac1562803cdbba505ab164f2577 467 Pfam PF16952 Glutamine synthetase N-terminal domain 25 110 3.2E-9 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS14880 83d1a1147e1290e521a82678af0dd1d7 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.6E-31 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS14880 83d1a1147e1290e521a82678af0dd1d7 67 SUPERFAMILY SSF50249 1 65 3.21E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS14880 83d1a1147e1290e521a82678af0dd1d7 67 PRINTS PR00050 Cold shock protein signature 4 19 7.9E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS14880 83d1a1147e1290e521a82678af0dd1d7 67 PRINTS PR00050 Cold shock protein signature 25 34 7.9E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS14880 83d1a1147e1290e521a82678af0dd1d7 67 PRINTS PR00050 Cold shock protein signature 40 58 7.9E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS14880 83d1a1147e1290e521a82678af0dd1d7 67 SMART SM00357 3 67 2.7E-31 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 LK06_RS14880 83d1a1147e1290e521a82678af0dd1d7 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site LK06_RS14880 83d1a1147e1290e521a82678af0dd1d7 67 PIRSF PIRSF002599 1 67 2.9E-26 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 LK06_RS14880 83d1a1147e1290e521a82678af0dd1d7 67 Gene3D G3DSA:2.40.50.140 1 65 1.7E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS06765 d3551bb320165ace671e0476502c8893 495 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 483 3.5E-190 T 06-07-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 465 5.4E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 Gene3D G3DSA:1.10.1060.10 2 147 6.5E-37 T 06-07-2017 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 Gene3D G3DSA:3.40.50.720 148 234 2.2E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06765 d3551bb320165ace671e0476502c8893 495 Gene3D G3DSA:3.40.50.720 415 490 2.2E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06765 d3551bb320165ace671e0476502c8893 495 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 41 131 2.8E-20 T 06-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 Gene3D G3DSA:3.50.50.60 235 409 1.4E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 1.5E-22 T 06-07-2017 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 1.5E-22 T 06-07-2017 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 1.5E-22 T 06-07-2017 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 1.5E-22 T 06-07-2017 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 SUPERFAMILY SSF51971 144 409 6.47E-57 T 06-07-2017 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 SUPERFAMILY SSF46548 5 155 7.85E-37 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 LK06_RS06765 d3551bb320165ace671e0476502c8893 495 SUPERFAMILY SSF51971 382 476 2.94E-12 T 06-07-2017 LK06_RS23085 21270e64356fb606f29480d9a2edfaf3 258 Gene3D G3DSA:3.40.50.150 5 234 1.6E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS23085 21270e64356fb606f29480d9a2edfaf3 258 SUPERFAMILY SSF53335 4 188 5.78E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS23085 21270e64356fb606f29480d9a2edfaf3 258 Pfam PF08241 Methyltransferase domain 49 148 1.3E-11 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS08500 782bb33e047ae2c32f41b1a0d5a93574 255 Gene3D G3DSA:3.40.50.150 7 236 3.0E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS08500 782bb33e047ae2c32f41b1a0d5a93574 255 Pfam PF08241 Methyltransferase domain 18 121 5.0E-23 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS08500 782bb33e047ae2c32f41b1a0d5a93574 255 SUPERFAMILY SSF53335 8 236 6.44E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS05130 903087181050d2f4c365886b441003e2 409 Gene3D G3DSA:3.40.50.620 37 326 4.9E-73 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS05130 903087181050d2f4c365886b441003e2 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 2.1E-18 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LK06_RS05130 903087181050d2f4c365886b441003e2 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 2.1E-18 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LK06_RS05130 903087181050d2f4c365886b441003e2 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 241 262 2.1E-18 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LK06_RS05130 903087181050d2f4c365886b441003e2 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 210 228 2.1E-18 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LK06_RS05130 903087181050d2f4c365886b441003e2 409 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 39 333 7.5E-79 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 LK06_RS05130 903087181050d2f4c365886b441003e2 409 SUPERFAMILY SSF52374 33 332 1.07E-65 T 06-07-2017 LK06_RS05130 903087181050d2f4c365886b441003e2 409 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 409 2.1E-203 T 06-07-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 LK06_RS05130 903087181050d2f4c365886b441003e2 409 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 409 53.31 T 06-07-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 SUPERFAMILY SSF50249 112 179 2.52E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 SUPERFAMILY SSF54814 259 324 9.16E-16 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 Pfam PF13184 NusA-like KH domain 210 278 1.4E-25 T 06-07-2017 IPR025249 KH domain, NusA-like GO:0003723 LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 Gene3D G3DSA:3.30.300.20 179 257 5.2E-33 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 330 25.842 T 06-07-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 Gene3D G3DSA:3.30.300.20 258 327 8.8E-31 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 Pfam PF08529 NusA N-terminal domain 6 103 7.1E-17 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 322 2.9E-105 T 06-07-2017 IPR010213 Transcription termination factor NusA GO:0003723 LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 SMART SM00316 113 178 3.2E-4 T 06-07-2017 IPR022967 RNA-binding domain, S1 LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 Gene3D G3DSA:3.30.1480.10 3 102 1.0E-30 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 SUPERFAMILY SSF54814 180 258 9.81E-28 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 SUPERFAMILY SSF69705 3 102 1.44E-27 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 LK06_RS24755 0dd2beee9d0016e3b61e0f5aa254f4b2 331 Gene3D G3DSA:2.40.50.140 109 178 4.9E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS08950 969b67e9523ad814fbc295c2376aec56 481 ProSitePatterns PS00455 Putative AMP-binding domain signature. 136 147 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS08950 969b67e9523ad814fbc295c2376aec56 481 Gene3D G3DSA:3.40.50.980 145 301 1.4E-34 T 06-07-2017 LK06_RS08950 969b67e9523ad814fbc295c2376aec56 481 SUPERFAMILY SSF56801 9 480 6.02E-123 T 06-07-2017 LK06_RS08950 969b67e9523ad814fbc295c2376aec56 481 Gene3D G3DSA:3.30.300.30 383 480 3.5E-29 T 06-07-2017 LK06_RS08950 969b67e9523ad814fbc295c2376aec56 481 Gene3D G3DSA:3.40.50.980 9 144 1.6E-24 T 06-07-2017 LK06_RS08950 969b67e9523ad814fbc295c2376aec56 481 Gene3D G3DSA:2.30.38.10 302 380 1.7E-25 T 06-07-2017 LK06_RS08950 969b67e9523ad814fbc295c2376aec56 481 Pfam PF13193 AMP-binding enzyme C-terminal domain 396 472 4.1E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS08950 969b67e9523ad814fbc295c2376aec56 481 Pfam PF00501 AMP-binding enzyme 10 386 8.6E-78 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS10850 ee198a993c51b810f8ca6166e1bbcb59 288 Gene3D G3DSA:3.40.50.150 25 276 3.7E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS10850 ee198a993c51b810f8ca6166e1bbcb59 288 Pfam PF01564 Spermine/spermidine synthase 59 186 8.7E-5 T 06-07-2017 LK06_RS10850 ee198a993c51b810f8ca6166e1bbcb59 288 SUPERFAMILY SSF53335 34 245 9.51E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS04300 0511d28fe453e2ef5c0e21a15759f856 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 8.0E-99 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS04300 0511d28fe453e2ef5c0e21a15759f856 250 Gene3D G3DSA:3.30.70.980 138 205 2.9E-24 T 06-07-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS04300 0511d28fe453e2ef5c0e21a15759f856 250 Gene3D G3DSA:3.30.1270.10 213 248 2.1E-40 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS04300 0511d28fe453e2ef5c0e21a15759f856 250 Gene3D G3DSA:3.30.1270.10 83 137 2.1E-40 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS04300 0511d28fe453e2ef5c0e21a15759f856 250 Pfam PF01709 Transcriptional regulator 5 238 4.2E-88 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS04300 0511d28fe453e2ef5c0e21a15759f856 250 SUPERFAMILY SSF75625 3 247 1.57E-89 T 06-07-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS04300 0511d28fe453e2ef5c0e21a15759f856 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.216 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS04300 0511d28fe453e2ef5c0e21a15759f856 250 Gene3D G3DSA:1.10.10.200 1 77 6.5E-31 T 06-07-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like LK06_RS16695 dd53ee59dff1579424769c99d4dde19d 163 Pfam PF14437 MafB19-like deaminase 16 162 9.6E-33 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 LK06_RS16695 dd53ee59dff1579424769c99d4dde19d 163 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 21 163 47.097 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 LK06_RS16695 dd53ee59dff1579424769c99d4dde19d 163 Gene3D G3DSA:3.40.140.10 14 163 1.9E-60 T 06-07-2017 LK06_RS16695 dd53ee59dff1579424769c99d4dde19d 163 SUPERFAMILY SSF53927 14 162 5.02E-53 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 LK06_RS16695 dd53ee59dff1579424769c99d4dde19d 163 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 68 105 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 LK06_RS18820 62c869aec220cb92497fe9a0e4c72a0c 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 221 372 2.3E-20 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS18820 62c869aec220cb92497fe9a0e4c72a0c 382 Gene3D G3DSA:1.10.540.10 2 111 3.5E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18820 62c869aec220cb92497fe9a0e4c72a0c 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 110 8.4E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18820 62c869aec220cb92497fe9a0e4c72a0c 382 SUPERFAMILY SSF56645 2 232 6.02E-64 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS18820 62c869aec220cb92497fe9a0e4c72a0c 382 SUPERFAMILY SSF47203 221 374 6.66E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS18820 62c869aec220cb92497fe9a0e4c72a0c 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 114 207 3.2E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS18820 62c869aec220cb92497fe9a0e4c72a0c 382 Gene3D G3DSA:2.40.110.10 113 209 2.2E-31 T 06-07-2017 LK06_RS18820 62c869aec220cb92497fe9a0e4c72a0c 382 Gene3D G3DSA:1.20.140.10 210 378 1.2E-22 T 06-07-2017 LK06_RS15460 12f1bba30c773e8077209e9ed9f144de 195 SUPERFAMILY SSF46689 2 86 1.13E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS15460 12f1bba30c773e8077209e9ed9f144de 195 SUPERFAMILY SSF48498 82 193 3.86E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS15460 12f1bba30c773e8077209e9ed9f144de 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 9.1E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS15460 12f1bba30c773e8077209e9ed9f144de 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS15460 12f1bba30c773e8077209e9ed9f144de 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS15460 12f1bba30c773e8077209e9ed9f144de 195 Gene3D G3DSA:1.10.10.60 2 59 6.8E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS15460 12f1bba30c773e8077209e9ed9f144de 195 Gene3D G3DSA:1.10.357.10 60 194 2.1E-44 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS02155 035fcb3e1147276fcf05dee349f0c1d0 119 PIRSF PIRSF009151 1 119 2.4E-59 T 06-07-2017 IPR008497 Protein of unknown function DUF779 LK06_RS02155 035fcb3e1147276fcf05dee349f0c1d0 119 Pfam PF05610 Protein of unknown function (DUF779) 17 116 2.1E-46 T 06-07-2017 IPR008497 Protein of unknown function DUF779 LK06_RS30515 e44727819cf0bd6b19aed610d133168c 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 7.7E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30515 e44727819cf0bd6b19aed610d133168c 230 SUPERFAMILY SSF48498 86 177 1.08E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS30515 e44727819cf0bd6b19aed610d133168c 230 Gene3D G3DSA:1.10.357.10 8 209 4.4E-46 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS30515 e44727819cf0bd6b19aed610d133168c 230 SUPERFAMILY SSF46689 7 68 1.55E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS30515 e44727819cf0bd6b19aed610d133168c 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30515 e44727819cf0bd6b19aed610d133168c 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30515 e44727819cf0bd6b19aed610d133168c 230 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 152 207 4.2E-9 T 06-07-2017 LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00448 2 115 4.9E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 194 3.5E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:1.10.10.10 144 201 7.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF46894 128 202 2.79E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00421 139 196 1.2E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF52172 1 127 1.37E-29 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:3.40.50.2300 1 143 5.2E-34 T 06-07-2017 LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS20150 5e671cd532bc3faaca485869e5a8630e 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS15905 9779e8761c670d65316b56f8e747ab63 205 Gene3D G3DSA:3.40.630.30 5 136 2.8E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS15905 9779e8761c670d65316b56f8e747ab63 205 SUPERFAMILY SSF55729 40 146 3.32E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS15905 9779e8761c670d65316b56f8e747ab63 205 Pfam PF00583 Acetyltransferase (GNAT) family 65 141 2.0E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS26025 fb98719b48f90027be0d05a40e0b333a 148 SUPERFAMILY SSF101386 20 123 2.04E-32 T 06-07-2017 LK06_RS26025 fb98719b48f90027be0d05a40e0b333a 148 Pfam PF12643 MazG-like family 51 122 1.4E-10 T 06-07-2017 IPR025984 MazG-like domain KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 LK06_RS26025 fb98719b48f90027be0d05a40e0b333a 148 Gene3D G3DSA:1.10.287.1080 12 114 8.6E-21 T 06-07-2017 LK06_RS22565 b1121a3f4beebe8c6fae7a5f6b570f2a 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 276 1.5E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS22565 b1121a3f4beebe8c6fae7a5f6b570f2a 309 Gene3D G3DSA:1.10.3720.10 62 277 1.5E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS22565 b1121a3f4beebe8c6fae7a5f6b570f2a 309 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 63 171 5.1E-20 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 LK06_RS22565 b1121a3f4beebe8c6fae7a5f6b570f2a 309 SUPERFAMILY SSF161098 62 262 6.67E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS20450 9c1c9187c933dc58ec066a709a7c1023 465 SMART SM00345 26 85 6.2E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS20450 9c1c9187c933dc58ec066a709a7c1023 465 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 1.1E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS20450 9c1c9187c933dc58ec066a709a7c1023 465 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 1.1E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS20450 9c1c9187c933dc58ec066a709a7c1023 465 Pfam PF00155 Aminotransferase class I and II 126 405 5.7E-17 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS20450 9c1c9187c933dc58ec066a709a7c1023 465 SUPERFAMILY SSF53383 93 463 1.9E-68 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS20450 9c1c9187c933dc58ec066a709a7c1023 465 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 85 1.0E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS20450 9c1c9187c933dc58ec066a709a7c1023 465 Gene3D G3DSA:1.10.10.10 26 88 1.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20450 9c1c9187c933dc58ec066a709a7c1023 465 SUPERFAMILY SSF46785 17 88 1.92E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20450 9c1c9187c933dc58ec066a709a7c1023 465 Gene3D G3DSA:3.40.640.10 144 355 4.4E-42 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS05680 724a428a4ef38a58cd1d059322b5ee47 356 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 218 232 - T 06-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 LK06_RS05680 724a428a4ef38a58cd1d059322b5ee47 356 Gene3D G3DSA:3.10.290.10 118 179 6.5E-22 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS05680 724a428a4ef38a58cd1d059322b5ee47 356 Pfam PF01479 S4 domain 120 165 6.1E-13 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS05680 724a428a4ef38a58cd1d059322b5ee47 356 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 185 343 1.2E-43 T 06-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 LK06_RS05680 724a428a4ef38a58cd1d059322b5ee47 356 Pfam PF00849 RNA pseudouridylate synthase 182 312 8.9E-24 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS05680 724a428a4ef38a58cd1d059322b5ee47 356 SUPERFAMILY SSF55174 111 185 9.42E-13 T 06-07-2017 LK06_RS05680 724a428a4ef38a58cd1d059322b5ee47 356 SUPERFAMILY SSF55120 165 354 1.05E-43 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS05680 724a428a4ef38a58cd1d059322b5ee47 356 SMART SM00363 120 180 1.1E-10 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS01325 b8f197c5170f2890a45f97e9d631ab5b 226 Pfam PF08281 Sigma-70, region 4 166 218 4.3E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01325 b8f197c5170f2890a45f97e9d631ab5b 226 SUPERFAMILY SSF88946 67 155 4.71E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01325 b8f197c5170f2890a45f97e9d631ab5b 226 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 86 219 1.5E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01325 b8f197c5170f2890a45f97e9d631ab5b 226 Gene3D G3DSA:1.10.1740.10 68 158 1.1E-11 T 06-07-2017 LK06_RS01325 b8f197c5170f2890a45f97e9d631ab5b 226 SUPERFAMILY SSF88659 147 223 3.36E-18 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01325 b8f197c5170f2890a45f97e9d631ab5b 226 Gene3D G3DSA:1.10.10.10 162 224 5.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01325 b8f197c5170f2890a45f97e9d631ab5b 226 Pfam PF04542 Sigma-70 region 2 75 139 5.3E-7 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01325 b8f197c5170f2890a45f97e9d631ab5b 226 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 70 223 1.0E-42 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 LK06_RS12185 29793109b64d0a72f6885e39788c68ae 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 2.4E-51 T 06-07-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12185 29793109b64d0a72f6885e39788c68ae 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 4.7E-32 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12185 29793109b64d0a72f6885e39788c68ae 126 Gene3D G3DSA:4.10.910.10 73 124 5.0E-26 T 06-07-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12185 29793109b64d0a72f6885e39788c68ae 126 SUPERFAMILY SSF46946 2 122 7.07E-45 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 LK06_RS12185 29793109b64d0a72f6885e39788c68ae 126 PIRSF PIRSF002134 1 125 4.1E-43 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12185 29793109b64d0a72f6885e39788c68ae 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 27.85 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12185 29793109b64d0a72f6885e39788c68ae 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 06-07-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12185 29793109b64d0a72f6885e39788c68ae 126 Gene3D G3DSA:1.10.8.50 1 72 2.6E-30 T 06-07-2017 LK06_RS27905 a6d01228144e9526de7a0a56271e107a 633 Pfam PF00753 Metallo-beta-lactamase superfamily 101 326 2.8E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS27905 a6d01228144e9526de7a0a56271e107a 633 Gene3D G3DSA:3.30.1050.10 538 620 1.4E-5 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS27905 a6d01228144e9526de7a0a56271e107a 633 SUPERFAMILY SSF55718 511 633 8.63E-26 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS27905 a6d01228144e9526de7a0a56271e107a 633 Gene3D G3DSA:3.60.15.10 230 350 1.8E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS27905 a6d01228144e9526de7a0a56271e107a 633 Gene3D G3DSA:3.60.15.10 70 194 1.8E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS27905 a6d01228144e9526de7a0a56271e107a 633 SMART SM00849 105 326 1.1E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS27905 a6d01228144e9526de7a0a56271e107a 633 Pfam PF14863 Alkyl sulfatase dimerisation 364 501 1.0E-62 T 06-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 LK06_RS27905 a6d01228144e9526de7a0a56271e107a 633 SUPERFAMILY SSF56281 7 503 6.94E-155 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS27905 a6d01228144e9526de7a0a56271e107a 633 Pfam PF14864 Alkyl sulfatase C-terminal 509 633 9.9E-37 T 06-07-2017 IPR029229 Alkyl sulfatase, C-terminal LK06_RS29320 83ff238b1c2ca12d56e89455fb437ea7 496 Pfam PF13520 Amino acid permease 17 411 7.4E-59 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS29320 83ff238b1c2ca12d56e89455fb437ea7 496 PIRSF PIRSF006060 4 470 7.1E-69 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 SUPERFAMILY SSF50621 248 385 2.27E-47 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 SUPERFAMILY SSF51419 18 256 2.18E-64 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 Gene3D G3DSA:2.40.37.10 234 385 8.6E-58 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 SMART SM01005 255 382 3.3E-63 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 Gene3D G3DSA:3.20.20.10 20 233 1.7E-71 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 Pfam PF01168 Alanine racemase, N-terminal domain 18 240 1.0E-66 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 41 51 - T 06-07-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 PRINTS PR00992 Alanine racemase signature 72 90 1.3E-59 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 PRINTS PR00992 Alanine racemase signature 309 326 1.3E-59 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 PRINTS PR00992 Alanine racemase signature 36 52 1.3E-59 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 PRINTS PR00992 Alanine racemase signature 271 286 1.3E-59 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 PRINTS PR00992 Alanine racemase signature 133 145 1.3E-59 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 PRINTS PR00992 Alanine racemase signature 170 181 1.3E-59 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 PRINTS PR00992 Alanine racemase signature 288 303 1.3E-59 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 PRINTS PR00992 Alanine racemase signature 213 240 1.3E-59 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 PRINTS PR00992 Alanine racemase signature 364 377 1.3E-59 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 TIGRFAM TIGR00492 alr: alanine racemase 14 382 2.2E-93 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 Pfam PF00842 Alanine racemase, C-terminal domain 255 381 2.2E-38 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS20055 80fa0db0a7f4e3d98bce4dea0046caec 388 Hamap MF_01201 Alanine racemase. 11 382 32.244 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 SUPERFAMILY SSF55124 305 437 2.78E-20 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 SUPERFAMILY SSF56014 173 334 4.19E-46 T 06-07-2017 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 SUPERFAMILY SSF55124 22 172 1.03E-38 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 102 162 1.5E-18 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 349 414 1.1E-15 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 Gene3D G3DSA:3.90.480.10 102 170 8.3E-49 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 Gene3D G3DSA:3.90.480.10 342 418 8.3E-49 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 Gene3D G3DSA:3.30.413.10 173 325 3.4E-44 T 06-07-2017 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 SUPERFAMILY SSF56014 422 563 2.22E-38 T 06-07-2017 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 PRINTS PR00397 Sirohaem Fe-binding site signature 471 489 1.4E-9 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 PRINTS PR00397 Sirohaem Fe-binding site signature 426 444 1.4E-9 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 Gene3D G3DSA:3.30.413.10 424 564 1.2E-38 T 06-07-2017 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 425 563 1.3E-11 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 173 327 2.8E-40 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS26970 eae18fd02dc7509f4a771085b3da34e4 565 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 471 487 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LK06_RS14150 ef69e9a51d455a44fcc20ff3b082a941 154 SUPERFAMILY SSF55298 1 152 2.98E-56 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS14150 ef69e9a51d455a44fcc20ff3b082a941 154 Gene3D G3DSA:3.30.1330.40 1 152 1.4E-68 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS14150 ef69e9a51d455a44fcc20ff3b082a941 154 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 151 3.1E-33 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS20500 fad711d88ae566ef459b1daf79e117cd 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.9E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20500 fad711d88ae566ef459b1daf79e117cd 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.9E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20500 fad711d88ae566ef459b1daf79e117cd 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.9E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20500 fad711d88ae566ef459b1daf79e117cd 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.9E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20500 fad711d88ae566ef459b1daf79e117cd 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.9E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20500 fad711d88ae566ef459b1daf79e117cd 258 Gene3D G3DSA:3.40.50.720 18 254 5.8E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20500 fad711d88ae566ef459b1daf79e117cd 258 SUPERFAMILY SSF51735 18 256 9.13E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20500 fad711d88ae566ef459b1daf79e117cd 258 Pfam PF00106 short chain dehydrogenase 18 204 9.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20500 fad711d88ae566ef459b1daf79e117cd 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS06255 cde2998241b9f5d4056c96778120603d 460 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 263 446 6.2E-26 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 LK06_RS06255 cde2998241b9f5d4056c96778120603d 460 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 194 1.4E-25 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain LK06_RS06255 cde2998241b9f5d4056c96778120603d 460 SUPERFAMILY SSF52317 262 457 5.69E-33 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS06255 cde2998241b9f5d4056c96778120603d 460 Gene3D G3DSA:3.40.50.300 53 195 6.6E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06255 cde2998241b9f5d4056c96778120603d 460 Gene3D G3DSA:3.40.50.300 5 49 4.0E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06255 cde2998241b9f5d4056c96778120603d 460 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 4 447 42.324 T 06-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 LK06_RS06255 cde2998241b9f5d4056c96778120603d 460 SUPERFAMILY SSF52540 5 198 5.32E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06255 cde2998241b9f5d4056c96778120603d 460 Gene3D G3DSA:3.40.50.880 262 459 3.4E-31 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS06255 cde2998241b9f5d4056c96778120603d 460 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 6 456 1.8E-123 T 06-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 LK06_RS04210 a7f2948dc0c2fccb94acca589e5825c7 204 Gene3D G3DSA:1.10.1050.10 1 97 3.5E-28 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 LK06_RS04210 a7f2948dc0c2fccb94acca589e5825c7 204 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 06-07-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS04210 a7f2948dc0c2fccb94acca589e5825c7 204 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 6 204 4.2E-62 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 LK06_RS04210 a7f2948dc0c2fccb94acca589e5825c7 204 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 6 91 5.0E-18 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 LK06_RS04210 a7f2948dc0c2fccb94acca589e5825c7 204 SUPERFAMILY SSF55174 6 204 3.14E-55 T 06-07-2017 LK06_RS04210 a7f2948dc0c2fccb94acca589e5825c7 204 Pfam PF01479 S4 domain 92 139 4.0E-18 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS04210 a7f2948dc0c2fccb94acca589e5825c7 204 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 204 30.05 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 LK06_RS04210 a7f2948dc0c2fccb94acca589e5825c7 204 SMART SM01390 3 91 7.1E-33 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 LK06_RS04210 a7f2948dc0c2fccb94acca589e5825c7 204 Gene3D G3DSA:3.10.290.10 98 188 9.9E-25 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS04210 a7f2948dc0c2fccb94acca589e5825c7 204 SMART SM00363 92 158 1.7E-16 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS30485 063b0e008a92ba3edfea48a92cb06434 330 Gene3D G3DSA:3.30.1180.20 185 329 1.6E-54 T 06-07-2017 LK06_RS30485 063b0e008a92ba3edfea48a92cb06434 330 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 326 2.7E-149 T 06-07-2017 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 LK06_RS30485 063b0e008a92ba3edfea48a92cb06434 330 SUPERFAMILY SSF82549 11 329 2.22E-118 T 06-07-2017 LK06_RS30485 063b0e008a92ba3edfea48a92cb06434 330 Gene3D G3DSA:3.40.50.10440 11 183 5.5E-70 T 06-07-2017 LK06_RS30485 063b0e008a92ba3edfea48a92cb06434 330 Pfam PF02733 Dak1 domain 17 325 2.1E-127 T 06-07-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 LK06_RS18090 b93ba5e714c9175ebd59983010b02439 338 Pfam PF13751 Transposase DDE domain 203 320 7.4E-23 T 06-07-2017 IPR025668 Transposase DDE domain LK06_RS18090 b93ba5e714c9175ebd59983010b02439 338 Pfam PF01609 Transposase DDE domain 82 177 4.7E-8 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS08720 119b5b5d7404f50d9668207081ca554b 187 Pfam PF14325 Domain of unknown function (DUF4383) 31 145 4.9E-11 T 06-07-2017 IPR025492 Protein of unknown function DUF4383 LK06_RS05390 76e75725e24ae3cc21a10598901e336e 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 2.9E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05390 76e75725e24ae3cc21a10598901e336e 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 2.9E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05390 76e75725e24ae3cc21a10598901e336e 249 Gene3D G3DSA:3.40.1410.10 91 245 3.4E-32 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS05390 76e75725e24ae3cc21a10598901e336e 249 Pfam PF07702 UTRA domain 104 240 1.4E-23 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS05390 76e75725e24ae3cc21a10598901e336e 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 2.3E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05390 76e75725e24ae3cc21a10598901e336e 249 SUPERFAMILY SSF64288 68 247 1.02E-30 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS05390 76e75725e24ae3cc21a10598901e336e 249 SMART SM00866 101 241 5.9E-18 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS05390 76e75725e24ae3cc21a10598901e336e 249 SUPERFAMILY SSF46785 13 82 1.56E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05390 76e75725e24ae3cc21a10598901e336e 249 Gene3D G3DSA:1.10.10.10 12 82 3.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05390 76e75725e24ae3cc21a10598901e336e 249 SMART SM00345 21 80 2.2E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS06715 0b58638e641d3be5a513f159ea52ad71 290 Gene3D G3DSA:3.20.20.190 17 287 1.1E-72 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS06715 0b58638e641d3be5a513f159ea52ad71 290 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 40 281 2.9E-39 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 LK06_RS06715 0b58638e641d3be5a513f159ea52ad71 290 SUPERFAMILY SSF51695 34 286 2.56E-68 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 SMART SM00859 2 113 1.3E-38 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 Gene3D G3DSA:3.40.50.720 1 134 4.5E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 Gene3D G3DSA:3.30.360.10 135 315 4.5E-71 T 06-07-2017 LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 236 250 - T 06-07-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 132 319 3.8E-53 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 112 3.6E-29 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 SUPERFAMILY SSF55347 122 320 2.43E-62 T 06-07-2017 LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 333 1.6E-127 T 06-07-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 333 32.752 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 PIRSF PIRSF000148 1 337 7.3E-109 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 LK06_RS10035 33149fb95138982ebca658ab0b7c1028 339 SUPERFAMILY SSF51735 2 149 6.04E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03895 2668355bae799cfb5566ea15687e18fb 513 Pfam PF13520 Amino acid permease 43 479 5.3E-56 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS03895 2668355bae799cfb5566ea15687e18fb 513 PIRSF PIRSF006060 22 511 1.5E-50 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS03895 2668355bae799cfb5566ea15687e18fb 513 ProSitePatterns PS00218 Amino acid permeases signature. 70 101 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 Gene3D G3DSA:3.40.50.1000 5 23 4.9E-40 T 06-07-2017 IPR023214 HAD-like domain LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 Gene3D G3DSA:3.40.50.1000 90 214 4.9E-40 T 06-07-2017 IPR023214 HAD-like domain LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 11 183 5.9E-16 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 SUPERFAMILY SSF56219 218 485 9.55E-33 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 99 112 4.4E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 4.4E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 4.4E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 4.4E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 Gene3D G3DSA:3.60.10.10 218 482 2.2E-17 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 185 1.3E-26 T 06-07-2017 IPR023214 HAD-like domain LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 222 475 3.1E-24 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS04005 bddc490ee69648ef40cdf164ba750242 487 SUPERFAMILY SSF56784 9 215 1.03E-44 T 06-07-2017 IPR023214 HAD-like domain LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 SUPERFAMILY SSF51621 1 75 4.54E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 SUPERFAMILY SSF51621 166 337 4.54E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 Gene3D G3DSA:2.40.33.10 73 167 2.0E-28 T 06-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 PRINTS PR01050 Pyruvate kinase family signature 185 199 1.7E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.7E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 PRINTS PR01050 Pyruvate kinase family signature 242 266 1.7E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 PRINTS PR01050 Pyruvate kinase family signature 311 327 1.7E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 PRINTS PR01050 Pyruvate kinase family signature 267 291 1.7E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 PRINTS PR01050 Pyruvate kinase family signature 292 310 1.7E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 PRINTS PR01050 Pyruvate kinase family signature 215 241 1.7E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 06-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 SUPERFAMILY SSF52935 321 472 1.57E-36 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 SUPERFAMILY SSF50800 70 165 1.4E-25 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 Gene3D G3DSA:3.20.20.60 168 324 1.1E-100 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 Gene3D G3DSA:3.20.20.60 2 72 1.1E-100 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 Gene3D G3DSA:3.40.1380.20 325 471 3.4E-42 T 06-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 357 469 9.9E-28 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 7.3E-124 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS06935 e512f55b152ecee492816b79cbaf2dda 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 471 2.4E-164 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS22570 29b75cd23762a9350bd914f865c0c7b8 318 SMART SM00062 65 306 1.6E-50 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LK06_RS22570 29b75cd23762a9350bd914f865c0c7b8 318 SUPERFAMILY SSF53850 22 303 2.95E-55 T 06-07-2017 LK06_RS22570 29b75cd23762a9350bd914f865c0c7b8 318 Gene3D G3DSA:3.40.190.10 267 304 8.5E-33 T 06-07-2017 LK06_RS22570 29b75cd23762a9350bd914f865c0c7b8 318 Gene3D G3DSA:3.40.190.10 62 156 8.5E-33 T 06-07-2017 LK06_RS22570 29b75cd23762a9350bd914f865c0c7b8 318 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 66 302 1.7E-60 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LK06_RS22570 29b75cd23762a9350bd914f865c0c7b8 318 Gene3D G3DSA:3.40.190.10 157 266 5.4E-22 T 06-07-2017 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 SUPERFAMILY SSF51604 143 413 2.4E-105 T 06-07-2017 IPR029065 Enolase C-terminal domain-like LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 SMART SM01192 142 414 5.5E-163 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 SUPERFAMILY SSF54826 5 139 5.52E-42 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 5 412 1.3E-159 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 Hamap MF_00318 Enolase [eno]. 3 413 39.486 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 Pfam PF03952 Enolase, N-terminal domain 5 135 7.6E-45 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 Gene3D G3DSA:3.30.390.10 4 125 1.2E-41 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 PIRSF PIRSF001400 1 416 1.4E-161 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 PRINTS PR00148 Enolase signature 38 52 3.2E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 PRINTS PR00148 Enolase signature 336 350 3.2E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 PRINTS PR00148 Enolase signature 313 324 3.2E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 PRINTS PR00148 Enolase signature 365 382 3.2E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 PRINTS PR00148 Enolase signature 108 124 3.2E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 PRINTS PR00148 Enolase signature 164 177 3.2E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 Pfam PF00113 Enolase, C-terminal TIM barrel domain 145 412 2.6E-108 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 SMART SM01193 5 135 3.7E-63 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LK06_RS19575 804b1bdfe8d80cd8759e28f285d21f32 423 Gene3D G3DSA:3.20.20.120 131 412 2.3E-111 T 06-07-2017 IPR029065 Enolase C-terminal domain-like LK06_RS17805 fe74594f1785636988edd8ba2ba77813 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 16 95 2.1E-20 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS17805 fe74594f1785636988edd8ba2ba77813 157 Gene3D G3DSA:1.20.1290.10 13 153 1.4E-47 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS17805 fe74594f1785636988edd8ba2ba77813 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 79 8.3E-20 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS17805 fe74594f1785636988edd8ba2ba77813 157 SUPERFAMILY SSF69118 14 153 3.4E-39 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS11080 deeb6cd5819cabfad42e5dba49ecddd4 340 SUPERFAMILY SSF48452 25 131 3.97E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS11080 deeb6cd5819cabfad42e5dba49ecddd4 340 Gene3D G3DSA:1.25.40.10 18 138 3.3E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18690 6e1465a526f46e071a33d1acb12952d9 369 Gene3D G3DSA:1.10.580.10 13 221 8.6E-46 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LK06_RS18690 6e1465a526f46e071a33d1acb12952d9 369 SUPERFAMILY SSF48256 3 354 8.64E-95 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS18690 6e1465a526f46e071a33d1acb12952d9 369 ProSitePatterns PS00480 Citrate synthase signature. 242 254 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LK06_RS18690 6e1465a526f46e071a33d1acb12952d9 369 Pfam PF00285 Citrate synthase, C-terminal domain 7 344 1.6E-84 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS18690 6e1465a526f46e071a33d1acb12952d9 369 PRINTS PR00143 Citrate synthase signature 160 175 4.9E-26 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS18690 6e1465a526f46e071a33d1acb12952d9 369 PRINTS PR00143 Citrate synthase signature 235 255 4.9E-26 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS18690 6e1465a526f46e071a33d1acb12952d9 369 PRINTS PR00143 Citrate synthase signature 294 310 4.9E-26 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS18690 6e1465a526f46e071a33d1acb12952d9 369 PRINTS PR00143 Citrate synthase signature 182 210 4.9E-26 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS18690 6e1465a526f46e071a33d1acb12952d9 369 PRINTS PR00143 Citrate synthase signature 314 328 4.9E-26 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS18690 6e1465a526f46e071a33d1acb12952d9 369 Gene3D G3DSA:1.10.230.10 222 306 1.2E-24 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 LK06_RS14445 e97f1f00e70b0b6c9595b3aacaa765d2 683 SUPERFAMILY SSF56317 11 297 5.36E-50 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS14445 e97f1f00e70b0b6c9595b3aacaa765d2 683 SUPERFAMILY SSF52402 614 645 4.42E-63 T 06-07-2017 LK06_RS14445 e97f1f00e70b0b6c9595b3aacaa765d2 683 SUPERFAMILY SSF52402 325 573 4.42E-63 T 06-07-2017 LK06_RS14445 e97f1f00e70b0b6c9595b3aacaa765d2 683 Pfam PF00795 Carbon-nitrogen hydrolase 13 282 8.0E-17 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS14445 e97f1f00e70b0b6c9595b3aacaa765d2 683 Gene3D G3DSA:3.40.50.620 617 645 1.1E-59 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS14445 e97f1f00e70b0b6c9595b3aacaa765d2 683 Gene3D G3DSA:3.40.50.620 327 576 1.1E-59 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS14445 e97f1f00e70b0b6c9595b3aacaa765d2 683 Gene3D G3DSA:3.60.110.10 13 296 2.4E-54 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS14445 e97f1f00e70b0b6c9595b3aacaa765d2 683 PIRSF PIRSF006630 9 668 7.0E-164 T 06-07-2017 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 LK06_RS14445 e97f1f00e70b0b6c9595b3aacaa765d2 683 Pfam PF02540 NAD synthase 348 521 1.9E-21 T 06-07-2017 IPR022310 NAD/GMP synthase LK06_RS09750 47c2ac31776d95e0031e159809897bbc 291 Gene3D G3DSA:1.10.10.10 84 155 1.0E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09750 47c2ac31776d95e0031e159809897bbc 291 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 7.6E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS09750 47c2ac31776d95e0031e159809897bbc 291 Pfam PF00392 Bacterial regulatory proteins, gntR family 86 134 5.0E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS09750 47c2ac31776d95e0031e159809897bbc 291 SUPERFAMILY SSF46785 11 78 3.3E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09750 47c2ac31776d95e0031e159809897bbc 291 SMART SM00345 16 75 2.7E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS09750 47c2ac31776d95e0031e159809897bbc 291 SMART SM00345 88 150 0.087 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS09750 47c2ac31776d95e0031e159809897bbc 291 Gene3D G3DSA:1.10.10.10 14 78 1.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09750 47c2ac31776d95e0031e159809897bbc 291 SUPERFAMILY SSF46785 84 139 5.92E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00960 0df3932d31a22644c384b9aa2eb51465 284 SUPERFAMILY SSF55447 178 281 1.44E-26 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal LK06_RS00960 0df3932d31a22644c384b9aa2eb51465 284 Gene3D G3DSA:3.30.465.10 58 174 1.3E-38 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS00960 0df3932d31a22644c384b9aa2eb51465 284 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 184 279 4.5E-20 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal LK06_RS00960 0df3932d31a22644c384b9aa2eb51465 284 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 9.2E-52 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 LK06_RS00960 0df3932d31a22644c384b9aa2eb51465 284 Gene3D G3DSA:3.30.43.10 1 54 3.1E-23 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS00960 0df3932d31a22644c384b9aa2eb51465 284 Gene3D G3DSA:3.30.390.50 180 280 9.0E-29 T 06-07-2017 LK06_RS00960 0df3932d31a22644c384b9aa2eb51465 284 SUPERFAMILY SSF56176 1 174 2.49E-59 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS00960 0df3932d31a22644c384b9aa2eb51465 284 SMART SM01092 180 280 1.3E-29 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal LK06_RS22625 61bcb4fc4618e791b4fd67e137e75763 764 Gene3D G3DSA:2.40.10.10 20 48 7.5E-4 T 06-07-2017 LK06_RS22625 61bcb4fc4618e791b4fd67e137e75763 764 Pfam PF13365 Trypsin-like peptidase domain 25 191 9.1E-12 T 06-07-2017 LK06_RS22625 61bcb4fc4618e791b4fd67e137e75763 764 SUPERFAMILY SSF50494 17 78 2.14E-18 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS22625 61bcb4fc4618e791b4fd67e137e75763 764 SUPERFAMILY SSF50494 107 222 2.14E-18 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS28850 9cedf4a1fc572eb1f0bf90b02e60e15c 300 Gene3D G3DSA:3.40.190.10 182 271 1.1E-26 T 06-07-2017 LK06_RS28850 9cedf4a1fc572eb1f0bf90b02e60e15c 300 Pfam PF03466 LysR substrate binding domain 88 298 4.9E-38 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS28850 9cedf4a1fc572eb1f0bf90b02e60e15c 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.6E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS28850 9cedf4a1fc572eb1f0bf90b02e60e15c 300 Gene3D G3DSA:1.10.10.10 2 87 3.1E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28850 9cedf4a1fc572eb1f0bf90b02e60e15c 300 SUPERFAMILY SSF46785 2 111 1.26E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28850 9cedf4a1fc572eb1f0bf90b02e60e15c 300 SUPERFAMILY SSF53850 89 297 3.58E-34 T 06-07-2017 LK06_RS28850 9cedf4a1fc572eb1f0bf90b02e60e15c 300 Gene3D G3DSA:3.40.190.10 89 181 1.4E-14 T 06-07-2017 LK06_RS02780 558793590c0866726e4682d03c083693 591 Gene3D G3DSA:1.10.1200.10 519 583 8.2E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02780 558793590c0866726e4682d03c083693 591 Pfam PF00501 AMP-binding enzyme 10 405 5.2E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS02780 558793590c0866726e4682d03c083693 591 ProSitePatterns PS00455 Putative AMP-binding domain signature. 152 163 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS02780 558793590c0866726e4682d03c083693 591 Gene3D G3DSA:3.30.300.30 402 518 7.0E-36 T 06-07-2017 LK06_RS02780 558793590c0866726e4682d03c083693 591 Gene3D G3DSA:3.40.50.980 157 313 2.2E-32 T 06-07-2017 LK06_RS02780 558793590c0866726e4682d03c083693 591 SMART SM00823 Phosphopantetheine attachment site 513 582 2.2E-10 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS02780 558793590c0866726e4682d03c083693 591 Pfam PF13193 AMP-binding enzyme C-terminal domain 414 488 4.4E-14 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS02780 558793590c0866726e4682d03c083693 591 Gene3D G3DSA:2.30.38.10 315 396 3.5E-25 T 06-07-2017 LK06_RS02780 558793590c0866726e4682d03c083693 591 Gene3D G3DSA:3.40.50.980 5 156 7.2E-44 T 06-07-2017 LK06_RS02780 558793590c0866726e4682d03c083693 591 SUPERFAMILY SSF56801 5 526 2.62E-138 T 06-07-2017 LK06_RS02780 558793590c0866726e4682d03c083693 591 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 33 430 6.2E-119 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS02780 558793590c0866726e4682d03c083693 591 SUPERFAMILY SSF47336 507 578 1.44E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02780 558793590c0866726e4682d03c083693 591 Pfam PF00550 Phosphopantetheine attachment site 514 578 4.7E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS04235 35a9cd7e592383a0387af47b354090e7 238 SUPERFAMILY SSF56281 6 225 1.12E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS04235 35a9cd7e592383a0387af47b354090e7 238 SMART SM00849 12 202 2.3E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS04235 35a9cd7e592383a0387af47b354090e7 238 Pfam PF00753 Metallo-beta-lactamase superfamily 9 202 2.2E-30 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS04235 35a9cd7e592383a0387af47b354090e7 238 Gene3D G3DSA:3.60.15.10 9 220 1.3E-50 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS26750 a2eaeb2221c326132c0c100c008e943f 373 SMART SM00382 24 218 9.8E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS26750 a2eaeb2221c326132c0c100c008e943f 373 SUPERFAMILY SSF52540 2 236 5.46E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26750 a2eaeb2221c326132c0c100c008e943f 373 Gene3D G3DSA:3.40.50.300 1 234 1.9E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26750 a2eaeb2221c326132c0c100c008e943f 373 Pfam PF00005 ABC transporter 16 160 7.8E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS26750 a2eaeb2221c326132c0c100c008e943f 373 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS03810 57f311d06d885f1224f23fdf985f1719 130 Pfam PF12796 Ankyrin repeats (3 copies) 20 105 2.2E-12 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain LK06_RS03810 57f311d06d885f1224f23fdf985f1719 130 SMART SM00248 77 106 0.07 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 LK06_RS03810 57f311d06d885f1224f23fdf985f1719 130 SMART SM00248 44 76 0.085 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 LK06_RS03810 57f311d06d885f1224f23fdf985f1719 130 Gene3D G3DSA:1.25.40.20 14 108 2.5E-21 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain LK06_RS03810 57f311d06d885f1224f23fdf985f1719 130 SUPERFAMILY SSF48403 14 127 1.71E-19 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 Pfam PF00067 Cytochrome P450 275 374 8.7E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 Pfam PF00067 Cytochrome P450 207 267 2.6E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 Gene3D G3DSA:1.10.630.10 9 405 2.9E-110 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 SUPERFAMILY SSF48264 11 405 8.91E-88 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 PRINTS PR00359 B-class P450 signature 91 102 1.4E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 PRINTS PR00359 B-class P450 signature 276 287 1.4E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 PRINTS PR00359 B-class P450 signature 140 156 1.4E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 PRINTS PR00359 B-class P450 signature 294 321 1.4E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 PRINTS PR00359 B-class P450 signature 353 364 1.4E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 PRINTS PR00359 B-class P450 signature 194 216 1.4E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 PRINTS PR00359 B-class P450 signature 344 353 1.4E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02670 7b9dc94aa3e43ef59f1d1767e7cee313 413 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS21965 c40aa71167fb5fa9b529e4067f97a9c6 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS21965 c40aa71167fb5fa9b529e4067f97a9c6 106 SUPERFAMILY SSF54862 3 92 8.38E-22 T 06-07-2017 LK06_RS21965 c40aa71167fb5fa9b529e4067f97a9c6 106 Pfam PF00037 4Fe-4S binding domain 34 55 1.2E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LK06_RS21965 c40aa71167fb5fa9b529e4067f97a9c6 106 Gene3D G3DSA:3.30.70.20 3 77 8.6E-20 T 06-07-2017 LK06_RS21965 c40aa71167fb5fa9b529e4067f97a9c6 106 PRINTS PR00354 7Fe ferredoxin signature 35 52 3.9E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 LK06_RS21965 c40aa71167fb5fa9b529e4067f97a9c6 106 PRINTS PR00354 7Fe ferredoxin signature 19 29 3.9E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 LK06_RS21965 c40aa71167fb5fa9b529e4067f97a9c6 106 PRINTS PR00354 7Fe ferredoxin signature 9 19 3.9E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 LK06_RS18995 8dccdd199d89eca3ca78dbf113611ca3 131 SUPERFAMILY SSF50475 36 109 1.49E-8 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS18995 8dccdd199d89eca3ca78dbf113611ca3 131 Gene3D G3DSA:2.30.110.10 35 104 6.8E-9 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS18995 8dccdd199d89eca3ca78dbf113611ca3 131 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 25 125 2.9E-23 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 LK06_RS18995 8dccdd199d89eca3ca78dbf113611ca3 131 Pfam PF04075 Domain of unknown function (DUF385) 9 128 5.2E-31 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 LK06_RS28350 d4d9743e837dc45112b851061da0c3d0 483 Pfam PF13579 Glycosyl transferase 4-like domain 97 271 2.1E-21 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS28350 d4d9743e837dc45112b851061da0c3d0 483 Pfam PF00534 Glycosyl transferases group 1 288 458 8.5E-27 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS28350 d4d9743e837dc45112b851061da0c3d0 483 Gene3D G3DSA:3.40.50.2000 262 456 7.2E-21 T 06-07-2017 LK06_RS28350 d4d9743e837dc45112b851061da0c3d0 483 SUPERFAMILY SSF53756 82 480 6.73E-67 T 06-07-2017 LK06_RS07350 399f72c3798ad56b73e78d3f4cc63142 346 SUPERFAMILY SSF52540 16 291 3.29E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07350 399f72c3798ad56b73e78d3f4cc63142 346 PIRSF PIRSF002849 2 321 1.8E-130 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted LK06_RS07350 399f72c3798ad56b73e78d3f4cc63142 346 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 47 176 6.5E-65 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 LK06_RS07350 399f72c3798ad56b73e78d3f4cc63142 346 Gene3D G3DSA:3.40.50.300 33 193 2.8E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07350 399f72c3798ad56b73e78d3f4cc63142 346 Gene3D G3DSA:1.10.8.300 210 315 1.4E-35 T 06-07-2017 LK06_RS06050 d2ca6fb94b73fdd3936c141bb85eb452 329 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 06-07-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS06050 d2ca6fb94b73fdd3936c141bb85eb452 329 SMART SM00729 11 207 6.1E-11 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS06050 d2ca6fb94b73fdd3936c141bb85eb452 329 Pfam PF06463 Molybdenum Cofactor Synthesis C 183 309 4.5E-37 T 06-07-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS06050 d2ca6fb94b73fdd3936c141bb85eb452 329 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 2 329 4.5E-111 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS06050 d2ca6fb94b73fdd3936c141bb85eb452 329 SUPERFAMILY SSF102114 3 277 1.16E-72 T 06-07-2017 LK06_RS06050 d2ca6fb94b73fdd3936c141bb85eb452 329 Pfam PF04055 Radical SAM superfamily 16 177 5.4E-31 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS06050 d2ca6fb94b73fdd3936c141bb85eb452 329 Gene3D G3DSA:3.20.20.70 2 306 7.6E-79 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS06050 d2ca6fb94b73fdd3936c141bb85eb452 329 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 2 329 41.183 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS06050 d2ca6fb94b73fdd3936c141bb85eb452 329 Pfam PF13353 4Fe-4S single cluster domain 18 104 1.9E-6 T 06-07-2017 LK06_RS26740 0b4dc6f3a5c334bf38d4cb60bc7ab8d6 135 Gene3D G3DSA:2.170.150.20 2 134 2.0E-60 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 LK06_RS26740 0b4dc6f3a5c334bf38d4cb60bc7ab8d6 135 Pfam PF01641 SelR domain 11 131 1.1E-52 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 LK06_RS26740 0b4dc6f3a5c334bf38d4cb60bc7ab8d6 135 SUPERFAMILY SSF51316 6 134 1.19E-55 T 06-07-2017 IPR011057 Mss4-like LK06_RS26740 0b4dc6f3a5c334bf38d4cb60bc7ab8d6 135 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 134 5.3E-50 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 LK06_RS21065 f6036be9f573f30baafc2e26840b9070 237 Pfam PF01061 ABC-2 type transporter 2 202 9.0E-26 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS21065 f6036be9f573f30baafc2e26840b9070 237 PIRSF PIRSF006648 1 237 2.4E-67 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS19210 be9d8acadd9ae8a7a9e3efecb607df6f 235 SMART SM00849 17 213 2.4E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS19210 be9d8acadd9ae8a7a9e3efecb607df6f 235 Pfam PF00753 Metallo-beta-lactamase superfamily 17 213 2.7E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS19210 be9d8acadd9ae8a7a9e3efecb607df6f 235 SUPERFAMILY SSF56281 1 220 5.28E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS19210 be9d8acadd9ae8a7a9e3efecb607df6f 235 Gene3D G3DSA:3.60.15.10 2 223 4.7E-42 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS12260 c16215a1b1ebdbc86f4559c2ab9ea14d 107 Pfam PF00467 KOW motif 5 36 1.9E-7 T 06-07-2017 IPR005824 KOW LK06_RS12260 c16215a1b1ebdbc86f4559c2ab9ea14d 107 SUPERFAMILY SSF50104 1 105 6.39E-31 T 06-07-2017 IPR008991 Translation protein SH3-like domain LK06_RS12260 c16215a1b1ebdbc86f4559c2ab9ea14d 107 Gene3D G3DSA:2.30.30.30 1 95 5.1E-27 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 LK06_RS12260 c16215a1b1ebdbc86f4559c2ab9ea14d 107 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 06-07-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12260 c16215a1b1ebdbc86f4559c2ab9ea14d 107 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 107 3.7E-24 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12260 c16215a1b1ebdbc86f4559c2ab9ea14d 107 SMART SM00739 2 29 1.0E-5 T 06-07-2017 IPR005824 KOW LK06_RS12260 c16215a1b1ebdbc86f4559c2ab9ea14d 107 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 101 21.516 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12260 c16215a1b1ebdbc86f4559c2ab9ea14d 107 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 107 3.6E-36 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 SUPERFAMILY SSF53633 1 300 3.01E-69 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 Gene3D G3DSA:3.40.1160.10 1 301 1.1E-86 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 Pfam PF00696 Amino acid kinase family 1 276 5.5E-30 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 PIRSF PIRSF000723 1 302 2.9E-102 T 06-07-2017 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 PRINTS PR01469 Bacterial carbamate kinase signature 257 272 3.5E-60 T 06-07-2017 LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 PRINTS PR01469 Bacterial carbamate kinase signature 206 221 3.5E-60 T 06-07-2017 LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 PRINTS PR01469 Bacterial carbamate kinase signature 103 122 3.5E-60 T 06-07-2017 LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 PRINTS PR01469 Bacterial carbamate kinase signature 151 170 3.5E-60 T 06-07-2017 LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 PRINTS PR01469 Bacterial carbamate kinase signature 72 90 3.5E-60 T 06-07-2017 LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 PRINTS PR01469 Bacterial carbamate kinase signature 174 192 3.5E-60 T 06-07-2017 LK06_RS29335 d59c6a89d3f3b53ab253b3a82ea7cc85 307 PRINTS PR01469 Bacterial carbamate kinase signature 41 60 3.5E-60 T 06-07-2017 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 TIGRFAM TIGR00416 sms: DNA repair protein RadA 9 450 4.2E-153 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 SUPERFAMILY SSF54211 293 453 1.4E-34 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 Hamap MF_01498 DNA repair protein RadA [radA]. 27 454 42.168 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 Gene3D G3DSA:3.40.50.300 68 275 8.1E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 Pfam PF13541 Subunit ChlI of Mg-chelatase 370 429 1.6E-8 T 06-07-2017 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 Gene3D G3DSA:3.30.230.10 284 453 1.6E-31 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 SUPERFAMILY SSF52540 71 293 1.07E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 SMART SM00382 90 244 2.1E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 PRINTS PR01874 DNA repair protein radA signature 82 110 8.0E-86 T 06-07-2017 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 PRINTS PR01874 DNA repair protein radA signature 248 274 8.0E-86 T 06-07-2017 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 PRINTS PR01874 DNA repair protein radA signature 124 141 8.0E-86 T 06-07-2017 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 PRINTS PR01874 DNA repair protein radA signature 322 345 8.0E-86 T 06-07-2017 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 PRINTS PR01874 DNA repair protein radA signature 174 198 8.0E-86 T 06-07-2017 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 PRINTS PR01874 DNA repair protein radA signature 16 40 8.0E-86 T 06-07-2017 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 PRINTS PR01874 DNA repair protein radA signature 213 241 8.0E-86 T 06-07-2017 LK06_RS13590 1e8a373a76a72eb662db42fabb3b8cd2 469 Pfam PF13481 AAA domain 77 222 5.9E-15 T 06-07-2017 LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 Gene3D G3DSA:2.60.40.10 6 148 1.9E-54 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 5.3E-18 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 SMART SM00642 155 565 6.5E-10 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 Pfam PF00128 Alpha amylase, catalytic domain 185 277 4.8E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 SUPERFAMILY SSF51445 130 468 2.15E-137 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 SUPERFAMILY SSF51445 497 573 2.15E-137 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 698 6.2E-302 T 06-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 Gene3D G3DSA:3.20.20.80 149 573 6.2E-128 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 Gene3D G3DSA:2.60.40.1180 589 699 3.2E-31 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 SUPERFAMILY SSF81296 6 144 1.01E-42 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS30990 f9fc2dcdbbd984ef517852c505db2b5e 710 SUPERFAMILY SSF51011 589 697 2.37E-23 T 06-07-2017 LK06_RS12800 787af541af7a69ca44903f93e8eb6b8c 392 Gene3D G3DSA:3.90.1150.10 267 388 6.9E-12 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS12800 787af541af7a69ca44903f93e8eb6b8c 392 SUPERFAMILY SSF53383 9 387 6.05E-93 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS12800 787af541af7a69ca44903f93e8eb6b8c 392 Gene3D G3DSA:3.40.640.10 51 266 2.4E-63 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS12800 787af541af7a69ca44903f93e8eb6b8c 392 Pfam PF00155 Aminotransferase class I and II 38 382 1.1E-34 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 Pfam PF00067 Cytochrome P450 16 440 1.2E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 Gene3D G3DSA:1.10.630.10 12 456 4.3E-113 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 PRINTS PR00465 E-class P450 group IV signature 405 423 1.2E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 PRINTS PR00465 E-class P450 group IV signature 260 286 1.2E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 PRINTS PR00465 E-class P450 group IV signature 316 332 1.2E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 PRINTS PR00465 E-class P450 group IV signature 349 363 1.2E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 PRINTS PR00465 E-class P450 group IV signature 365 383 1.2E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 PRINTS PR00465 E-class P450 group IV signature 389 405 1.2E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 398 407 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 SUPERFAMILY SSF48264 12 454 6.55E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 PRINTS PR00385 P450 superfamily signature 269 286 4.9E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 PRINTS PR00385 P450 superfamily signature 405 416 4.9E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 PRINTS PR00385 P450 superfamily signature 321 332 4.9E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02465 6ae46cf5316e66c77f7138f49c82b1da 457 PRINTS PR00385 P450 superfamily signature 396 405 4.9E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22190 e7fd9baa5c99dae782ead84e573aafc3 960 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 659 947 4.7E-33 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD LK06_RS22190 e7fd9baa5c99dae782ead84e573aafc3 960 SUPERFAMILY SSF56112 389 491 1.92E-6 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS22190 e7fd9baa5c99dae782ead84e573aafc3 960 Gene3D G3DSA:1.10.510.10 428 493 1.2E-4 T 06-07-2017 LK06_RS28815 1f68659f2ba241dab303e342df40b98a 785 SUPERFAMILY SSF55874 213 356 1.11E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS28815 1f68659f2ba241dab303e342df40b98a 785 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 251 356 3.1E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS28815 1f68659f2ba241dab303e342df40b98a 785 Gene3D G3DSA:3.30.565.10 213 357 1.0E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS28815 1f68659f2ba241dab303e342df40b98a 785 SMART SM00387 246 359 0.0015 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25000 8eb410089d3e9927eb9aac4b801c27e0 124 SUPERFAMILY SSF47413 3 72 1.46E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS25000 8eb410089d3e9927eb9aac4b801c27e0 124 Pfam PF13560 Helix-turn-helix domain 8 65 3.4E-11 T 06-07-2017 LK06_RS25000 8eb410089d3e9927eb9aac4b801c27e0 124 SMART SM00530 11 66 1.4E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS25000 8eb410089d3e9927eb9aac4b801c27e0 124 Gene3D G3DSA:1.10.260.40 8 75 5.5E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS15810 f16870db830345652066843c4c42778e 385 Gene3D G3DSA:1.10.150.130 68 169 5.5E-19 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS15810 f16870db830345652066843c4c42778e 385 Gene3D G3DSA:1.10.443.10 177 372 1.1E-33 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS15810 f16870db830345652066843c4c42778e 385 Pfam PF00589 Phage integrase family 183 363 6.2E-20 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS15810 f16870db830345652066843c4c42778e 385 SUPERFAMILY SSF56349 68 372 1.59E-61 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS15810 f16870db830345652066843c4c42778e 385 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 69 124 2.4E-11 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS30280 bc35fad06d6a8978c767f4b8685231c8 376 Gene3D G3DSA:3.40.50.1100 66 163 8.3E-20 T 06-07-2017 LK06_RS30280 bc35fad06d6a8978c767f4b8685231c8 376 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 36 319 4.2E-47 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS30280 bc35fad06d6a8978c767f4b8685231c8 376 Gene3D G3DSA:3.40.50.1100 164 332 6.0E-39 T 06-07-2017 LK06_RS30280 bc35fad06d6a8978c767f4b8685231c8 376 SUPERFAMILY SSF53686 34 338 2.1E-62 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS26850 c2ab18a67e91d5f501d40341ab79ce10 189 SUPERFAMILY SSF49879 101 180 1.76E-24 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS26850 c2ab18a67e91d5f501d40341ab79ce10 189 Gene3D G3DSA:2.60.200.20 102 181 5.2E-24 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS26850 c2ab18a67e91d5f501d40341ab79ce10 189 Pfam PF08044 Domain of unknown function (DUF1707) 13 64 7.3E-17 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 LK06_RS26850 c2ab18a67e91d5f501d40341ab79ce10 189 SMART SM00240 109 159 2.7E-13 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS26850 c2ab18a67e91d5f501d40341ab79ce10 189 Pfam PF00498 FHA domain 111 174 4.5E-17 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 11 644 50.734 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 Pfam PF13193 AMP-binding enzyme C-terminal domain 532 610 7.3E-26 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 Gene3D G3DSA:3.40.50.980 267 425 7.1E-28 T 06-07-2017 LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 26 642 7.5E-297 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 31 83 4.9E-20 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 Pfam PF00501 AMP-binding enzyme 90 523 8.9E-91 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 Gene3D G3DSA:3.40.50.980 81 266 2.1E-42 T 06-07-2017 LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 Gene3D G3DSA:2.30.38.10 440 516 7.1E-7 T 06-07-2017 LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 Gene3D G3DSA:3.30.300.30 520 641 1.9E-28 T 06-07-2017 LK06_RS14090 f9ea70331611a32fd3b91e2827372b8b 651 SUPERFAMILY SSF56801 32 640 1.05E-176 T 06-07-2017 LK06_RS16255 0ecf9160ff1784d20107e1be376e2ad7 151 SUPERFAMILY SSF110087 10 143 2.22E-30 T 06-07-2017 IPR007410 DR1885-like metal-binding protein LK06_RS16255 0ecf9160ff1784d20107e1be376e2ad7 151 Pfam PF04314 Protein of unknown function (DUF461) 34 135 5.1E-26 T 06-07-2017 IPR007410 DR1885-like metal-binding protein LK06_RS28235 c86c2d18a8cb127563e25953f9394796 282 Pfam PF02634 FdhD/NarQ family 26 273 5.4E-80 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 LK06_RS28235 c86c2d18a8cb127563e25953f9394796 282 Gene3D G3DSA:3.40.140.10 138 276 9.6E-56 T 06-07-2017 LK06_RS28235 c86c2d18a8cb127563e25953f9394796 282 Gene3D G3DSA:3.10.20.10 28 120 4.1E-26 T 06-07-2017 LK06_RS28235 c86c2d18a8cb127563e25953f9394796 282 PIRSF PIRSF015626 1 277 1.8E-92 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 LK06_RS28235 c86c2d18a8cb127563e25953f9394796 282 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 274 6.7E-51 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 LK06_RS28235 c86c2d18a8cb127563e25953f9394796 282 SUPERFAMILY SSF53927 4 273 9.02E-80 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 LK06_RS28235 c86c2d18a8cb127563e25953f9394796 282 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 274 34.366 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 SUPERFAMILY SSF47323 583 820 3.92E-51 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 SUPERFAMILY SSF52374 352 581 3.33E-135 T 06-07-2017 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 SUPERFAMILY SSF52374 15 206 3.33E-135 T 06-07-2017 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 TIGRFAM TIGR00422 valS: valine--tRNA ligase 17 852 0.0 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 807 871 1.8E-15 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 SUPERFAMILY SSF46589 807 871 3.45E-14 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 Gene3D G3DSA:3.90.740.10 205 345 1.3E-44 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 Gene3D G3DSA:1.10.730.10 572 746 7.8E-56 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 567 1.4E-190 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 Pfam PF08264 Anticodon-binding domain of tRNA 613 754 1.1E-36 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 PRINTS PR00986 Valyl-tRNA synthetase signature 242 259 1.9E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 PRINTS PR00986 Valyl-tRNA synthetase signature 50 61 1.9E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 PRINTS PR00986 Valyl-tRNA synthetase signature 451 472 1.9E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 PRINTS PR00986 Valyl-tRNA synthetase signature 357 370 1.9E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 PRINTS PR00986 Valyl-tRNA synthetase signature 482 500 1.9E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 Hamap MF_02004 Valine--tRNA ligase [valS]. 16 872 15.276 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 SUPERFAMILY SSF50677 206 345 2.09E-53 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 Gene3D G3DSA:3.40.50.620 352 569 8.5E-138 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 Gene3D G3DSA:3.40.50.620 19 204 8.5E-138 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS09895 08ea3513d6ce97f3b5e80dfd2dd2ad32 874 Gene3D G3DSA:1.10.287.380 800 871 2.5E-8 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 LK06_RS29725 3856e26b49901750143611b215031374 200 SUPERFAMILY SSF52833 76 169 1.63E-13 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS29725 3856e26b49901750143611b215031374 200 Gene3D G3DSA:3.40.30.10 75 193 2.5E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS29725 3856e26b49901750143611b215031374 200 Pfam PF13899 Thioredoxin-like 77 162 2.7E-16 T 06-07-2017 LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 SUPERFAMILY SSF47781 93 155 9.89E-10 T 06-07-2017 IPR010994 RuvA domain 2-like LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 SMART SM00382 366 547 0.0089 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 Gene3D G3DSA:3.40.50.300 318 529 4.5E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 Pfam PF14520 Helix-hairpin-helix domain 104 153 2.0E-6 T 06-07-2017 LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 SUPERFAMILY SSF52540 194 277 1.99E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 SUPERFAMILY SSF52540 349 505 1.99E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 Gene3D G3DSA:1.10.150.20 104 148 0.001 T 06-07-2017 LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 Pfam PF13604 AAA domain 353 531 2.4E-44 T 06-07-2017 LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 SUPERFAMILY SSF52540 462 529 5.11E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 SUPERFAMILY SSF52540 570 736 5.11E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 Pfam PF13538 UvrD-like helicase C-terminal domain 675 723 1.4E-19 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 18 746 1.1E-198 T 06-07-2017 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 Gene3D G3DSA:3.40.50.300 662 727 1.7E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 14 759 28.916 T 06-07-2017 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 LK06_RS10615 8378bc07f0a9f69225c59c6101c320ad 767 Pfam PF14490 Helix-hairpin-helix containing domain 154 244 1.3E-30 T 06-07-2017 IPR029493 RecD helicase-like helix-hairpin-helix domain LK06_RS29945 1dcf7392c553c51241426be830caf4f2 169 SUPERFAMILY SSF50475 14 165 1.18E-42 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS29945 1dcf7392c553c51241426be830caf4f2 169 Pfam PF01613 Flavin reductase like domain 22 167 1.7E-36 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS29945 1dcf7392c553c51241426be830caf4f2 169 SMART SM00903 22 166 4.7E-49 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS29945 1dcf7392c553c51241426be830caf4f2 169 Gene3D G3DSA:2.30.110.10 13 164 1.9E-53 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS02840 5696180ef99871049097001c83300b76 385 SUPERFAMILY SSF53067 86 371 1.43E-43 T 06-07-2017 LK06_RS02840 5696180ef99871049097001c83300b76 385 Gene3D G3DSA:3.30.420.40 226 350 1.9E-23 T 06-07-2017 LK06_RS02840 5696180ef99871049097001c83300b76 385 Gene3D G3DSA:1.10.10.10 11 81 5.1E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02840 5696180ef99871049097001c83300b76 385 Pfam PF00480 ROK family 89 367 3.8E-33 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS02840 5696180ef99871049097001c83300b76 385 Pfam PF12802 MarR family 20 66 2.5E-7 T 06-07-2017 LK06_RS02840 5696180ef99871049097001c83300b76 385 SUPERFAMILY SSF46785 11 72 1.22E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02840 5696180ef99871049097001c83300b76 385 Gene3D G3DSA:3.30.420.40 84 225 7.3E-39 T 06-07-2017 LK06_RS23935 e3d4e93f23da63ae9c57605d83205fef 389 Pfam PF07995 Glucose / Sorbosone dehydrogenase 73 373 2.7E-71 T 06-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 LK06_RS23935 e3d4e93f23da63ae9c57605d83205fef 389 Gene3D G3DSA:2.120.10.30 58 387 4.8E-85 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like LK06_RS23935 e3d4e93f23da63ae9c57605d83205fef 389 SUPERFAMILY SSF50952 65 373 1.57E-47 T 06-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 LK06_RS00385 955c248aba1e7f840bc0515ed4af0e20 603 Gene3D G3DSA:3.90.76.10 78 166 7.4E-11 T 06-07-2017 LK06_RS00385 955c248aba1e7f840bc0515ed4af0e20 603 Gene3D G3DSA:3.40.190.10 167 341 1.1E-34 T 06-07-2017 LK06_RS00385 955c248aba1e7f840bc0515ed4af0e20 603 Gene3D G3DSA:3.10.105.10 342 568 1.6E-29 T 06-07-2017 LK06_RS00385 955c248aba1e7f840bc0515ed4af0e20 603 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 509 5.3E-45 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS00385 955c248aba1e7f840bc0515ed4af0e20 603 SUPERFAMILY SSF53850 235 600 8.32E-67 T 06-07-2017 LK06_RS00385 955c248aba1e7f840bc0515ed4af0e20 603 SUPERFAMILY SSF53850 63 207 8.32E-67 T 06-07-2017 LK06_RS11800 0f7f448c716f308104ac580dd86602ff 436 Pfam PF01345 Domain of unknown function DUF11 27 96 1.4E-9 T 06-07-2017 IPR001434 Domain of unknown function DUF11 LK06_RS11800 0f7f448c716f308104ac580dd86602ff 436 Pfam PF01882 Protein of unknown function DUF58 192 277 1.5E-19 T 06-07-2017 IPR002881 Domain of unknown function DUF58 LK06_RS17950 773b5a60c4ee819073a0e2e5608592d5 206 Pfam PF10935 Protein of unknown function (DUF2637) 6 117 2.9E-19 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 LK06_RS08855 d7a015a8102c457a2dfb27e5e2bd755f 355 SUPERFAMILY SSF53901 10 353 4.53E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08855 d7a015a8102c457a2dfb27e5e2bd755f 355 Gene3D G3DSA:3.40.47.10 13 181 3.0E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08855 d7a015a8102c457a2dfb27e5e2bd755f 355 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 8.5E-25 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS08855 d7a015a8102c457a2dfb27e5e2bd755f 355 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 354 60.466 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS08855 d7a015a8102c457a2dfb27e5e2bd755f 355 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 264 353 6.8E-31 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS08855 d7a015a8102c457a2dfb27e5e2bd755f 355 Gene3D G3DSA:3.40.47.10 216 352 7.3E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 SMART SM00387 358 486 1.5E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 SUPERFAMILY SSF47384 231 318 6.87E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 Pfam PF00672 HAMP domain 168 235 5.9E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 426 7.9E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 464 7.9E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 7.9E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 440 7.9E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 318 4.9E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 SUPERFAMILY SSF55874 308 484 4.98E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 SMART SM00304 187 239 1.6E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 SUPERFAMILY SSF158472 189 236 9.42E-7 T 06-07-2017 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 Gene3D G3DSA:3.30.565.10 306 485 2.6E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 485 1.4E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 SMART SM00388 247 318 1.5E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS20765 ea200c430103464f9e85cd3807d5d1a4 513 Gene3D G3DSA:1.10.287.130 239 305 6.8E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS07470 136d727994168c9847fcc46aa9f5a668 450 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 11 450 1.6E-237 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 LK06_RS07470 136d727994168c9847fcc46aa9f5a668 450 SUPERFAMILY SSF51569 12 448 3.44E-197 T 06-07-2017 LK06_RS07470 136d727994168c9847fcc46aa9f5a668 450 Pfam PF01474 Class-II DAHP synthetase family 13 444 3.5E-200 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 LK06_RS23415 78be294016c5504569e94cc0f62f78b3 319 SUPERFAMILY SSF52540 2 225 7.44E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23415 78be294016c5504569e94cc0f62f78b3 319 SMART SM00382 26 204 4.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS23415 78be294016c5504569e94cc0f62f78b3 319 Gene3D G3DSA:3.40.50.300 1 224 9.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23415 78be294016c5504569e94cc0f62f78b3 319 Pfam PF00005 ABC transporter 18 156 2.3E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS00025 8806a8e5d9a368bb31a3cbfe274f4fa2 413 SUPERFAMILY SSF103473 25 408 2.49E-36 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS00025 8806a8e5d9a368bb31a3cbfe274f4fa2 413 Gene3D G3DSA:1.20.1250.20 28 204 3.5E-15 T 06-07-2017 LK06_RS00025 8806a8e5d9a368bb31a3cbfe274f4fa2 413 Gene3D G3DSA:1.20.1250.20 237 409 6.4E-13 T 06-07-2017 LK06_RS00025 8806a8e5d9a368bb31a3cbfe274f4fa2 413 Pfam PF07690 Major Facilitator Superfamily 274 409 6.5E-9 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS00025 8806a8e5d9a368bb31a3cbfe274f4fa2 413 Pfam PF07690 Major Facilitator Superfamily 52 261 4.6E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS00860 733ac7726e99fdb988c3980582c12793 780 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 327 696 3.7E-141 T 06-07-2017 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 LK06_RS00860 733ac7726e99fdb988c3980582c12793 780 SUPERFAMILY SSF48208 278 748 2.21E-120 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS00860 733ac7726e99fdb988c3980582c12793 780 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 700 750 1.6E-16 T 06-07-2017 IPR005194 Glycoside hydrolase family 65, C-terminal LK06_RS00860 733ac7726e99fdb988c3980582c12793 780 Gene3D G3DSA:2.60.420.10 682 751 1.4E-24 T 06-07-2017 LK06_RS00860 733ac7726e99fdb988c3980582c12793 780 PIRSF PIRSF036289 1 760 3.0E-225 T 06-07-2017 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase LK06_RS00860 733ac7726e99fdb988c3980582c12793 780 SUPERFAMILY SSF74650 5 270 4.08E-67 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 LK06_RS00860 733ac7726e99fdb988c3980582c12793 780 Gene3D G3DSA:1.50.10.10 321 681 2.3E-129 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 LK06_RS00860 733ac7726e99fdb988c3980582c12793 780 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 270 2.5E-61 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 LK06_RS00860 733ac7726e99fdb988c3980582c12793 780 Gene3D G3DSA:2.70.98.40 5 270 1.4E-73 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 SUPERFAMILY SSF63882 68 235 6.67E-31 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 Pfam PF00994 Probable molybdopterin binding domain 240 374 8.0E-22 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 Gene3D G3DSA:3.90.105.10 201 220 9.2E-11 T 06-07-2017 LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 Gene3D G3DSA:3.90.105.10 77 98 9.2E-11 T 06-07-2017 LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 SMART SM00852 239 375 5.9E-23 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 SUPERFAMILY SSF63867 384 447 8.34E-5 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 Pfam PF03453 MoeA N-terminal region (domain I and II) 59 226 3.5E-29 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 SUPERFAMILY SSF53218 236 377 1.57E-27 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 Gene3D G3DSA:2.40.340.10 388 438 9.6E-4 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 Gene3D G3DSA:3.40.980.10 221 387 4.7E-41 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 Pfam PF03454 MoeA C-terminal region (domain IV) 387 449 2.2E-6 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS15430 78d4852b25f9c96a53d915ad1ec229e2 463 Gene3D G3DSA:2.170.190.11 99 199 4.3E-15 T 06-07-2017 LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 3.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 3.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 3.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 Gene3D G3DSA:3.40.50.720 19 259 1.5E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 259 9.1E-56 T 06-07-2017 LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 2.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 2.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 2.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 2.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 SUPERFAMILY SSF51735 20 259 2.76E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27700 c5415297edadcaa2cc374b4d05b17b12 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 21 199 1.3E-5 T 06-07-2017 LK06_RS12580 e1c5a34352add4156d1148546b3b67d4 194 Gene3D G3DSA:1.20.120.450 8 161 1.2E-30 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase LK06_RS12580 e1c5a34352add4156d1148546b3b67d4 194 Pfam PF04978 Protein of unknown function (DUF664) 9 158 1.0E-42 T 06-07-2017 IPR007061 Protein of unknown function DUF664 LK06_RS12580 e1c5a34352add4156d1148546b3b67d4 194 SUPERFAMILY SSF109854 8 157 3.66E-35 T 06-07-2017 LK06_RS20985 e42b41de3b7489ee2242c8c16e840e63 335 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS20985 e42b41de3b7489ee2242c8c16e840e63 335 SMART SM00382 29 218 1.9E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS20985 e42b41de3b7489ee2242c8c16e840e63 335 Pfam PF00005 ABC transporter 20 163 2.8E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS20985 e42b41de3b7489ee2242c8c16e840e63 335 Gene3D G3DSA:3.40.50.300 3 234 7.6E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20985 e42b41de3b7489ee2242c8c16e840e63 335 SUPERFAMILY SSF52540 3 231 6.29E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20985 e42b41de3b7489ee2242c8c16e840e63 335 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 4.0E-9 T 06-07-2017 IPR025302 Domain of unknown function DUF4162 LK06_RS20985 e42b41de3b7489ee2242c8c16e840e63 335 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 5.9E-111 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 205 4.9E-16 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 Gene3D G3DSA:1.10.357.10 2 210 1.1E-60 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 7.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 7.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 PRINTS PR00400 Tetracycline repressor protein signature 26 49 5.5E-11 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 PRINTS PR00400 Tetracycline repressor protein signature 188 202 5.5E-11 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 PRINTS PR00400 Tetracycline repressor protein signature 79 98 5.5E-11 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 SUPERFAMILY SSF46689 2 65 3.14E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.6E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS05345 a430a7f85fd4d44a5790ec1904c2dfb9 213 SUPERFAMILY SSF48498 78 207 1.24E-27 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS07780 3700c9d07a76c4ac72de04a1041c3a79 506 Pfam PF13692 Glycosyl transferases group 1 293 435 3.8E-27 T 06-07-2017 LK06_RS07780 3700c9d07a76c4ac72de04a1041c3a79 506 Pfam PF11997 Domain of unknown function (DUF3492) 6 268 7.3E-58 T 06-07-2017 IPR022622 Domain of unknown function DUF3492 LK06_RS07780 3700c9d07a76c4ac72de04a1041c3a79 506 SUPERFAMILY SSF53756 175 470 7.18E-68 T 06-07-2017 LK06_RS07780 3700c9d07a76c4ac72de04a1041c3a79 506 SUPERFAMILY SSF53756 7 88 7.18E-68 T 06-07-2017 LK06_RS07780 3700c9d07a76c4ac72de04a1041c3a79 506 Gene3D G3DSA:3.40.50.2000 268 449 5.8E-23 T 06-07-2017 LK06_RS17580 658b2e26d25b27ca3d7aeac99c2bd3d6 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 51 7.6E-15 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS17580 658b2e26d25b27ca3d7aeac99c2bd3d6 341 SUPERFAMILY SSF53822 64 338 2.16E-59 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS17580 658b2e26d25b27ca3d7aeac99c2bd3d6 341 SMART SM00354 3 74 7.4E-27 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS17580 658b2e26d25b27ca3d7aeac99c2bd3d6 341 Gene3D G3DSA:3.40.50.2300 57 173 7.1E-37 T 06-07-2017 LK06_RS17580 658b2e26d25b27ca3d7aeac99c2bd3d6 341 Gene3D G3DSA:3.40.50.2300 174 339 1.2E-48 T 06-07-2017 LK06_RS17580 658b2e26d25b27ca3d7aeac99c2bd3d6 341 Gene3D G3DSA:1.10.260.40 4 56 1.6E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS17580 658b2e26d25b27ca3d7aeac99c2bd3d6 341 SUPERFAMILY SSF47413 3 62 1.13E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS17580 658b2e26d25b27ca3d7aeac99c2bd3d6 341 Pfam PF13377 Periplasmic binding protein-like domain 171 337 2.4E-29 T 06-07-2017 LK06_RS30050 2855e067d9c2baf517c97f40de925184 82 Pfam PF02126 Phosphotriesterase family 2 80 1.5E-4 T 06-07-2017 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 LK06_RS30050 2855e067d9c2baf517c97f40de925184 82 Gene3D G3DSA:3.20.20.140 1 80 1.6E-14 T 06-07-2017 LK06_RS30050 2855e067d9c2baf517c97f40de925184 82 SUPERFAMILY SSF51556 3 78 2.61E-10 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS07740 5766c1bdeeec067153230be9f9452243 400 Gene3D G3DSA:3.60.15.10 2 75 7.2E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS07740 5766c1bdeeec067153230be9f9452243 400 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 225 397 3.0E-51 T 06-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS07740 5766c1bdeeec067153230be9f9452243 400 Gene3D G3DSA:3.40.50.300 225 398 1.4E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07740 5766c1bdeeec067153230be9f9452243 400 SUPERFAMILY SSF56281 2 184 6.29E-7 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS07740 5766c1bdeeec067153230be9f9452243 400 SUPERFAMILY SSF52540 225 398 9.56E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22935 9f84b345c7ff97321ae0618169077d80 490 SUPERFAMILY SSF52540 25 406 4.25E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11265 e6df4c35cf8c2be87d398d3eadefdce8 784 Pfam PF05547 Immune inhibitor A peptidase M6 101 775 4.8E-240 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 LK06_RS11265 e6df4c35cf8c2be87d398d3eadefdce8 784 PIRSF PIRSF007519 1 784 5.2E-239 T 06-07-2017 IPR012300 Peptidase M6, InhA LK06_RS11265 e6df4c35cf8c2be87d398d3eadefdce8 784 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 151 457 1.9E-86 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 LK06_RS11265 e6df4c35cf8c2be87d398d3eadefdce8 784 SUPERFAMILY SSF55486 327 405 1.32E-16 T 06-07-2017 LK06_RS11265 e6df4c35cf8c2be87d398d3eadefdce8 784 SUPERFAMILY SSF55486 214 273 1.32E-16 T 06-07-2017 LK06_RS11265 e6df4c35cf8c2be87d398d3eadefdce8 784 Gene3D G3DSA:3.40.390.10 214 264 1.4E-27 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 LK06_RS11265 e6df4c35cf8c2be87d398d3eadefdce8 784 Gene3D G3DSA:3.40.390.10 327 405 1.4E-27 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 Gene3D G3DSA:3.90.700.10 250 383 1.1E-34 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 Gene3D G3DSA:3.50.50.60 5 249 4.0E-105 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 Gene3D G3DSA:3.50.50.60 385 451 4.0E-105 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 PIRSF PIRSF000171 1 595 8.5E-38 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 SUPERFAMILY SSF56425 243 389 8.67E-33 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 394 416 7.2E-7 T 06-07-2017 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 7.2E-7 T 06-07-2017 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 Pfam PF00890 FAD binding domain 10 430 2.2E-93 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 SUPERFAMILY SSF51905 6 270 7.62E-73 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 SUPERFAMILY SSF51905 395 462 7.62E-73 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 Gene3D G3DSA:1.20.58.100 483 579 6.4E-31 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 SUPERFAMILY SSF46977 484 646 1.44E-35 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS21795 9c4940aea96a904bc9a260b3e4deaa85 651 Pfam PF02910 Fumarate reductase flavoprotein C-term 491 588 4.4E-23 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20810 07d65483fa001abf017997e5346da032 555 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 327 434 7.3E-16 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 Gene3D G3DSA:3.40.120.10 313 442 1.0E-33 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 230 319 4.8E-22 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 Gene3D G3DSA:3.40.120.10 234 312 1.2E-20 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 SUPERFAMILY SSF53738 215 320 1.81E-20 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 SUPERFAMILY SSF55957 441 541 1.57E-16 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 SUPERFAMILY SSF53738 35 190 1.53E-41 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 45 182 3.9E-40 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 472 536 3.2E-10 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 SUPERFAMILY SSF53738 307 439 1.02E-26 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 Gene3D G3DSA:3.30.310.50 464 541 9.6E-22 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS20810 07d65483fa001abf017997e5346da032 555 Gene3D G3DSA:3.40.120.10 19 220 1.1E-59 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 SMART SM00382 30 210 4.8E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 SMART SM00382 315 491 1.2E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 SUPERFAMILY SSF52540 295 488 4.71E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 Gene3D G3DSA:3.40.50.300 7 251 3.6E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 Pfam PF16326 ABC transporter C-terminal domain 539 600 3.6E-8 T 06-07-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 Pfam PF12848 ABC transporter 198 256 2.8E-8 T 06-07-2017 IPR032781 ABC-transporter extension domain LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 SUPERFAMILY SSF52540 5 208 2.46E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 Gene3D G3DSA:3.40.50.300 289 530 1.1E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 Pfam PF00005 ABC transporter 306 447 1.8E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS19720 3775284bc5038f9b1ddd4c5c19935d5a 602 Pfam PF00005 ABC transporter 21 159 1.0E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS28840 4a7545468794e7ca42bd88d14064ce48 342 SMART SM00829 12 338 0.0074 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS28840 4a7545468794e7ca42bd88d14064ce48 342 SUPERFAMILY SSF50129 2 173 1.32E-51 T 06-07-2017 IPR011032 GroES-like LK06_RS28840 4a7545468794e7ca42bd88d14064ce48 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LK06_RS28840 4a7545468794e7ca42bd88d14064ce48 342 Gene3D G3DSA:3.40.50.720 173 287 1.8E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28840 4a7545468794e7ca42bd88d14064ce48 342 SUPERFAMILY SSF51735 142 297 1.23E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28840 4a7545468794e7ca42bd88d14064ce48 342 Pfam PF00107 Zinc-binding dehydrogenase 174 301 1.9E-23 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS28840 4a7545468794e7ca42bd88d14064ce48 342 Gene3D G3DSA:3.90.180.10 2 172 1.1E-47 T 06-07-2017 IPR011032 GroES-like LK06_RS28840 4a7545468794e7ca42bd88d14064ce48 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 133 1.6E-32 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS28840 4a7545468794e7ca42bd88d14064ce48 342 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 340 57.222 T 06-07-2017 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 LK06_RS01805 556c2cfb2de4ac6a64e3198fc3b2f808 732 Gene3D G3DSA:3.40.50.300 32 208 1.7E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01805 556c2cfb2de4ac6a64e3198fc3b2f808 732 Pfam PF00271 Helicase conserved C-terminal domain 275 376 2.4E-18 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS01805 556c2cfb2de4ac6a64e3198fc3b2f808 732 SMART SM00487 36 239 1.4E-35 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS01805 556c2cfb2de4ac6a64e3198fc3b2f808 732 Gene3D G3DSA:3.40.50.300 270 392 1.1E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01805 556c2cfb2de4ac6a64e3198fc3b2f808 732 SMART SM00490 297 378 8.1E-23 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS01805 556c2cfb2de4ac6a64e3198fc3b2f808 732 SUPERFAMILY SSF52540 251 389 7.41E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01805 556c2cfb2de4ac6a64e3198fc3b2f808 732 SUPERFAMILY SSF52540 51 212 7.41E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01805 556c2cfb2de4ac6a64e3198fc3b2f808 732 Pfam PF00270 DEAD/DEAH box helicase 42 210 2.4E-27 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS09585 72a069afd4a660109610468fad7da551 536 SUPERFAMILY SSF140490 322 418 9.02E-18 T 06-07-2017 LK06_RS09585 72a069afd4a660109610468fad7da551 536 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 330 409 1.6E-16 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS09585 72a069afd4a660109610468fad7da551 536 SUPERFAMILY SSF142019 32 239 7.59E-33 T 06-07-2017 LK06_RS09585 72a069afd4a660109610468fad7da551 536 Gene3D G3DSA:3.30.70.20 450 513 1.5E-12 T 06-07-2017 LK06_RS09585 72a069afd4a660109610468fad7da551 536 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 55 217 2.1E-30 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS09585 72a069afd4a660109610468fad7da551 536 SUPERFAMILY SSF142984 242 316 2.62E-8 T 06-07-2017 LK06_RS09585 72a069afd4a660109610468fad7da551 536 SUPERFAMILY SSF54862 450 510 1.76E-7 T 06-07-2017 LK06_RS09585 72a069afd4a660109610468fad7da551 536 SMART SM00928 325 369 5.6E-5 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS09585 72a069afd4a660109610468fad7da551 536 Pfam PF13459 4Fe-4S single cluster domain 451 509 1.9E-13 T 06-07-2017 LK06_RS01395 8805e1a3949aae9fa486afc31b381e29 115 SUPERFAMILY SSF54593 6 113 2.61E-25 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS01395 8805e1a3949aae9fa486afc31b381e29 115 Gene3D G3DSA:3.10.180.10 1 114 4.1E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS01395 8805e1a3949aae9fa486afc31b381e29 115 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 106 3.3E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS25855 ffac37f796c4d567a1c2d4bbc22bde2f 449 Pfam PF16221 winged helix-turn-helix 373 448 3.7E-32 T 06-07-2017 IPR032622 UCP01524, winged helix-turn-helix domain LK06_RS25855 ffac37f796c4d567a1c2d4bbc22bde2f 449 Gene3D G3DSA:3.40.630.10 163 361 1.3E-9 T 06-07-2017 LK06_RS25855 ffac37f796c4d567a1c2d4bbc22bde2f 449 Pfam PF09940 Domain of unknown function (DUF2172) 59 150 2.7E-39 T 06-07-2017 IPR032610 Domain of unknown function DUF2172 LK06_RS25855 ffac37f796c4d567a1c2d4bbc22bde2f 449 Pfam PF16254 Domain of unknown function (DUF4910) 9 234 1.2E-62 T 06-07-2017 IPR032589 Domain of unknown function DUF4910 LK06_RS25855 ffac37f796c4d567a1c2d4bbc22bde2f 449 Pfam PF16254 Domain of unknown function (DUF4910) 258 371 2.0E-45 T 06-07-2017 IPR032589 Domain of unknown function DUF4910 LK06_RS25855 ffac37f796c4d567a1c2d4bbc22bde2f 449 SUPERFAMILY SSF53187 83 368 5.54E-35 T 06-07-2017 LK06_RS19705 92efc1b055f3cc18f55919344b19601b 487 Pfam PF06737 Transglycosylase-like domain 408 481 2.6E-22 T 06-07-2017 IPR010618 Transglycosylase-like LK06_RS19705 92efc1b055f3cc18f55919344b19601b 487 Pfam PF07501 G5 domain 326 399 4.3E-20 T 06-07-2017 IPR011098 G5 domain LK06_RS19705 92efc1b055f3cc18f55919344b19601b 487 Gene3D G3DSA:1.10.530.10 385 485 2.8E-29 T 06-07-2017 LK06_RS19705 92efc1b055f3cc18f55919344b19601b 487 SUPERFAMILY SSF53955 408 484 7.29E-23 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS19705 92efc1b055f3cc18f55919344b19601b 487 Pfam PF03990 Domain of unknown function (DUF348) 212 242 4.1E-8 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 LK06_RS19705 92efc1b055f3cc18f55919344b19601b 487 Pfam PF03990 Domain of unknown function (DUF348) 155 195 1.1E-11 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 LK06_RS19705 92efc1b055f3cc18f55919344b19601b 487 Pfam PF03990 Domain of unknown function (DUF348) 269 307 2.2E-10 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 LK06_RS19705 92efc1b055f3cc18f55919344b19601b 487 SMART SM01208 322 400 4.6E-23 T 06-07-2017 IPR011098 G5 domain LK06_RS23835 9cd35efa0614e1e00951a936ef2ff3b8 389 Pfam PF00266 Aminotransferase class-V 3 372 5.0E-61 T 06-07-2017 IPR000192 Aminotransferase class V domain LK06_RS23835 9cd35efa0614e1e00951a936ef2ff3b8 389 SUPERFAMILY SSF53383 2 381 1.28E-93 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS23835 9cd35efa0614e1e00951a936ef2ff3b8 389 Gene3D G3DSA:3.40.640.10 17 250 1.7E-72 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS23835 9cd35efa0614e1e00951a936ef2ff3b8 389 Gene3D G3DSA:3.90.1150.10 251 376 6.6E-39 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS23835 9cd35efa0614e1e00951a936ef2ff3b8 389 PIRSF PIRSF005572 1 386 2.3E-109 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 LK06_RS28375 71ac667983065dac750a416bd0653b51 230 SUPERFAMILY SSF46689 12 92 4.26E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS28375 71ac667983065dac750a416bd0653b51 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 1.5E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS28375 71ac667983065dac750a416bd0653b51 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS28375 71ac667983065dac750a416bd0653b51 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS28375 71ac667983065dac750a416bd0653b51 230 SUPERFAMILY SSF48498 90 215 1.25E-34 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS28375 71ac667983065dac750a416bd0653b51 230 Gene3D G3DSA:1.10.357.10 7 216 4.4E-46 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS00060 cc30baa0ff7b7acc1c9c1620882e9e12 412 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 50 66 1.4E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LK06_RS00060 cc30baa0ff7b7acc1c9c1620882e9e12 412 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 113 123 1.4E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LK06_RS00060 cc30baa0ff7b7acc1c9c1620882e9e12 412 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 92 110 1.4E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LK06_RS00060 cc30baa0ff7b7acc1c9c1620882e9e12 412 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 302 315 1.4E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LK06_RS00060 cc30baa0ff7b7acc1c9c1620882e9e12 412 Gene3D G3DSA:3.40.50.2300 316 374 1.1E-5 T 06-07-2017 LK06_RS00060 cc30baa0ff7b7acc1c9c1620882e9e12 412 Pfam PF13458 Periplasmic binding protein 50 385 3.9E-61 T 06-07-2017 IPR028081 Leucine-binding protein domain LK06_RS00060 cc30baa0ff7b7acc1c9c1620882e9e12 412 SUPERFAMILY SSF53822 50 388 2.76E-61 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS00060 cc30baa0ff7b7acc1c9c1620882e9e12 412 Gene3D G3DSA:3.40.50.2300 50 244 7.5E-40 T 06-07-2017 LK06_RS11945 ca6be41d844b357f8f661a6164108867 587 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 188 350 1.0E-47 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS11945 ca6be41d844b357f8f661a6164108867 587 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 466 559 2.9E-11 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain LK06_RS11945 ca6be41d844b357f8f661a6164108867 587 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 188 351 9.9E-40 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 SMART SM00304 229 291 1.2E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 Gene3D G3DSA:3.30.565.10 352 520 1.7E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 Gene3D G3DSA:1.10.287.130 292 351 1.4E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 Pfam PF00512 His Kinase A (phospho-acceptor) domain 301 366 2.0E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 SMART SM00388 299 366 2.0E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 474 8.6E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 499 8.6E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 517 8.6E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 460 8.6E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 SUPERFAMILY SSF55874 355 519 1.44E-42 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 Pfam PF00672 HAMP domain 212 287 6.1E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 410 517 1.2E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 SMART SM00387 409 520 1.5E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16620 583e8f5fa9fe36add564dfedcd83e4d5 550 SUPERFAMILY SSF47384 285 367 1.67E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS05760 de996d46a29e00371999d8217c8b0c0c 301 Gene3D G3DSA:3.40.50.10330 7 152 3.0E-33 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 LK06_RS05760 de996d46a29e00371999d8217c8b0c0c 301 SUPERFAMILY SSF111331 8 297 5.49E-80 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain LK06_RS05760 de996d46a29e00371999d8217c8b0c0c 301 Hamap MF_00361 NAD kinase [nadK]. 7 291 29.819 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 LK06_RS05760 de996d46a29e00371999d8217c8b0c0c 301 Gene3D G3DSA:2.60.200.30 153 265 1.4E-37 T 06-07-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 LK06_RS05760 de996d46a29e00371999d8217c8b0c0c 301 Pfam PF01513 ATP-NAD kinase 56 275 5.1E-58 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 LK06_RS22175 d4de5fa36c22d0e59f5a64a8e3247b6b 392 SUPERFAMILY SSF69572 7 357 4.45E-107 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 LK06_RS22175 d4de5fa36c22d0e59f5a64a8e3247b6b 392 Pfam PF00899 ThiF family 21 254 1.2E-66 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 LK06_RS22175 d4de5fa36c22d0e59f5a64a8e3247b6b 392 SMART SM00450 290 387 1.6E-23 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS22175 d4de5fa36c22d0e59f5a64a8e3247b6b 392 Gene3D G3DSA:3.40.50.720 12 258 4.8E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22175 d4de5fa36c22d0e59f5a64a8e3247b6b 392 Pfam PF00581 Rhodanese-like domain 290 383 2.6E-13 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS22175 d4de5fa36c22d0e59f5a64a8e3247b6b 392 Gene3D G3DSA:3.40.250.10 274 387 4.7E-28 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS23660 19e4059deb50dc11b2eb1581ab609afb 618 ProSitePatterns PS00211 ABC transporters family signature. 515 529 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS23660 19e4059deb50dc11b2eb1581ab609afb 618 Gene3D G3DSA:1.20.1560.10 42 358 1.3E-74 T 06-07-2017 LK06_RS23660 19e4059deb50dc11b2eb1581ab609afb 618 SUPERFAMILY SSF90123 42 360 2.88E-62 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS23660 19e4059deb50dc11b2eb1581ab609afb 618 SUPERFAMILY SSF52540 375 612 9.37E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23660 19e4059deb50dc11b2eb1581ab609afb 618 Gene3D G3DSA:3.40.50.300 378 605 2.6E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23660 19e4059deb50dc11b2eb1581ab609afb 618 Pfam PF00005 ABC transporter 397 543 4.5E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS23660 19e4059deb50dc11b2eb1581ab609afb 618 SMART SM00382 403 589 6.3E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS23660 19e4059deb50dc11b2eb1581ab609afb 618 Pfam PF00664 ABC transporter transmembrane region 54 321 2.1E-30 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS31370 1744389cd355352063be978ac674ea66 289 Pfam PF13230 Glutamine amidotransferases class-II 28 254 2.7E-20 T 06-07-2017 IPR026869 Putative glutamine amidotransferase type 2 LK06_RS31370 1744389cd355352063be978ac674ea66 289 Gene3D G3DSA:3.60.20.10 2 255 5.7E-49 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS31370 1744389cd355352063be978ac674ea66 289 SUPERFAMILY SSF56235 2 256 5.92E-34 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 SUPERFAMILY SSF48452 796 940 6.17E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 Gene3D G3DSA:1.25.40.10 266 267 1.7E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 Gene3D G3DSA:1.25.40.10 109 219 1.7E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 SUPERFAMILY SSF52540 251 526 3.32E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 SMART SM00862 19 91 9.0E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 Pfam PF00486 Transcriptional regulatory protein, C terminal 30 91 8.2E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 PRINTS PR00364 Disease resistance protein signature 282 297 2.7E-5 T 06-07-2017 LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 PRINTS PR00364 Disease resistance protein signature 366 380 2.7E-5 T 06-07-2017 LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 PRINTS PR00364 Disease resistance protein signature 459 473 2.7E-5 T 06-07-2017 LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 Pfam PF03704 Bacterial transcriptional activator domain 98 240 3.5E-37 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 SUPERFAMILY SSF48452 95 256 9.87E-30 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 SUPERFAMILY SSF46894 15 91 8.79E-11 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 SMART SM01043 98 240 2.0E-40 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 Gene3D G3DSA:1.10.10.10 14 93 1.2E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08240 bd7e8705ce6bd0055b8537f9ba95277a 1085 Gene3D G3DSA:1.25.40.10 818 992 1.1E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 76 92 1.8E-5 T 06-07-2017 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 1.8E-5 T 06-07-2017 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 Gene3D G3DSA:3.60.120.10 211 689 1.7E-143 T 06-07-2017 IPR005801 ADC synthase GO:0009058 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 3.5E-12 T 06-07-2017 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 3.5E-12 T 06-07-2017 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00096 Glutamine amidotransferase superfamily signature 76 87 3.5E-12 T 06-07-2017 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 323 684 8.5E-106 T 06-07-2017 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 Pfam PF04715 Anthranilate synthase component I, N terminal region 226 367 4.1E-16 T 06-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 Pfam PF00425 chorismate binding enzyme 427 681 1.8E-88 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 SUPERFAMILY SSF52317 1 190 3.55E-52 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 Pfam PF00117 Glutamine amidotransferase class-I 4 184 3.4E-42 T 06-07-2017 IPR017926 Glutamine amidotransferase LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 SUPERFAMILY SSF56322 213 689 4.19E-124 T 06-07-2017 IPR005801 ADC synthase GO:0009058 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 184 1.2E-48 T 06-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 Gene3D G3DSA:3.40.50.880 1 188 1.6E-62 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00097 Anthranilate synthase component II signature 164 177 8.8E-31 T 06-07-2017 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00097 Anthranilate synthase component II signature 76 87 8.8E-31 T 06-07-2017 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00097 Anthranilate synthase component II signature 3 17 8.8E-31 T 06-07-2017 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00097 Anthranilate synthase component II signature 121 133 8.8E-31 T 06-07-2017 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00097 Anthranilate synthase component II signature 101 109 8.8E-31 T 06-07-2017 LK06_RS27185 8bca0986da3bf825403d1ee817498042 724 PRINTS PR00097 Anthranilate synthase component II signature 48 57 8.8E-31 T 06-07-2017 LK06_RS18635 0140f4e38d59d8ca3f1973be0dc43f9d 118 SUPERFAMILY SSF158560 1 110 6.8E-28 T 06-07-2017 LK06_RS18635 0140f4e38d59d8ca3f1973be0dc43f9d 118 Gene3D G3DSA:1.10.1900.10 17 115 1.0E-28 T 06-07-2017 IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein GO:0003723 LK06_RS18635 0140f4e38d59d8ca3f1973be0dc43f9d 118 Pfam PF06304 Protein of unknown function (DUF1048) 10 109 1.1E-28 T 06-07-2017 IPR008316 Uncharacterised conserved protein UCP029876 LK06_RS18825 bd74103c7487fbd38e872b9ece00129e 349 Gene3D G3DSA:3.40.50.720 178 284 3.4E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS18825 bd74103c7487fbd38e872b9ece00129e 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 141 7.1E-27 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS18825 bd74103c7487fbd38e872b9ece00129e 349 Gene3D G3DSA:3.90.180.10 1 177 2.5E-57 T 06-07-2017 IPR011032 GroES-like LK06_RS18825 bd74103c7487fbd38e872b9ece00129e 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LK06_RS18825 bd74103c7487fbd38e872b9ece00129e 349 SUPERFAMILY SSF51735 147 314 6.76E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS18825 bd74103c7487fbd38e872b9ece00129e 349 SUPERFAMILY SSF50129 12 180 2.43E-50 T 06-07-2017 IPR011032 GroES-like LK06_RS18825 bd74103c7487fbd38e872b9ece00129e 349 Pfam PF00107 Zinc-binding dehydrogenase 185 305 8.4E-18 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS18825 bd74103c7487fbd38e872b9ece00129e 349 SMART SM00829 12 347 3.9E-7 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS22220 873dfe4f46461535e1727e570aa5c190 248 SUPERFAMILY SSF53335 45 173 1.19E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS22220 873dfe4f46461535e1727e570aa5c190 248 Pfam PF08241 Methyltransferase domain 68 164 2.4E-17 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS22220 873dfe4f46461535e1727e570aa5c190 248 Gene3D G3DSA:3.40.50.150 60 172 2.7E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS15890 de9b0c43218ac7a6e69afaa49de97ccc 238 Pfam PF02527 rRNA small subunit methyltransferase G 24 197 1.5E-54 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 LK06_RS15890 de9b0c43218ac7a6e69afaa49de97ccc 238 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 194 23.57 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 LK06_RS15890 de9b0c43218ac7a6e69afaa49de97ccc 238 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 27 184 1.9E-36 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 LK06_RS15890 de9b0c43218ac7a6e69afaa49de97ccc 238 Gene3D G3DSA:3.40.50.150 26 212 1.8E-58 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS15890 de9b0c43218ac7a6e69afaa49de97ccc 238 SUPERFAMILY SSF53335 26 202 5.1E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS06605 8b58b9a4541e4780422e32093944aebd 111 Pfam PF13397 RNA polymerase-binding protein 5 108 3.9E-43 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 LK06_RS06605 8b58b9a4541e4780422e32093944aebd 111 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 110 23.856 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 LK06_RS06605 8b58b9a4541e4780422e32093944aebd 111 ProSitePatterns PS00202 Rubredoxin signature. 51 61 - T 06-07-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 Pfam PF00005 ABC transporter 302 449 3.4E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 SUPERFAMILY SSF49879 9 86 1.47E-21 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 SMART SM00382 311 505 7.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 SUPERFAMILY SSF52540 279 517 1.61E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 Gene3D G3DSA:2.60.200.20 9 86 5.9E-23 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 ProSitePatterns PS00211 ABC transporters family signature. 421 435 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 SMART SM00240 196 247 9.9E-16 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 SMART SM00240 20 70 7.9E-13 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 Gene3D G3DSA:3.40.50.300 288 510 1.3E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 Pfam PF00498 FHA domain 21 84 9.8E-16 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 Pfam PF00498 FHA domain 198 264 8.1E-18 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 Gene3D G3DSA:2.60.200.20 138 287 1.2E-24 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 Pfam PF01061 ABC-2 type transporter 575 793 2.3E-16 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS05935 0720ae6e0a65cac41070fea725122ae0 856 SUPERFAMILY SSF49879 142 291 4.21E-30 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS24400 c8f6aaea26506b7a74a93ad004c8160c 285 Gene3D G3DSA:3.40.50.720 61 169 2.5E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS24400 c8f6aaea26506b7a74a93ad004c8160c 285 SUPERFAMILY SSF53335 7 213 9.7E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS24400 c8f6aaea26506b7a74a93ad004c8160c 285 Gene3D G3DSA:3.40.50.150 8 60 2.3E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS06725 1a16dd3df8aeb1c3b63336d17e33dc46 143 Gene3D G3DSA:3.10.180.10 5 139 7.2E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS06725 1a16dd3df8aeb1c3b63336d17e33dc46 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 138 6.2E-8 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS06725 1a16dd3df8aeb1c3b63336d17e33dc46 143 SUPERFAMILY SSF54593 4 142 6.04E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30745 a6b193991126566d0728687ba6003698 171 Gene3D G3DSA:1.20.120.450 1 167 5.7E-69 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase LK06_RS30745 a6b193991126566d0728687ba6003698 171 Pfam PF04978 Protein of unknown function (DUF664) 14 166 1.9E-19 T 06-07-2017 IPR007061 Protein of unknown function DUF664 LK06_RS30745 a6b193991126566d0728687ba6003698 171 SUPERFAMILY SSF109854 4 166 4.43E-31 T 06-07-2017 LK06_RS19420 bd858cbb4a91557f8752e0471453932c 468 Gene3D G3DSA:1.10.150.130 70 168 2.4E-17 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS19420 bd858cbb4a91557f8752e0471453932c 468 Pfam PF00589 Phage integrase family 177 361 2.0E-20 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS19420 bd858cbb4a91557f8752e0471453932c 468 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 71 123 1.9E-7 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS19420 bd858cbb4a91557f8752e0471453932c 468 Gene3D G3DSA:1.10.443.10 173 368 7.2E-39 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS19420 bd858cbb4a91557f8752e0471453932c 468 SUPERFAMILY SSF56349 70 369 1.21E-63 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS30545 0dbb1866540e236d09d88813c8811897 520 Pfam PF01593 Flavin containing amine oxidoreductase 21 300 5.8E-10 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 LK06_RS30545 0dbb1866540e236d09d88813c8811897 520 Gene3D G3DSA:3.50.50.60 9 76 1.3E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30545 0dbb1866540e236d09d88813c8811897 520 Gene3D G3DSA:3.50.50.60 211 305 1.3E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30545 0dbb1866540e236d09d88813c8811897 520 SUPERFAMILY SSF51905 10 323 2.96E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02785 b934be71c4d13b0ab000742fa3de2eb9 507 Gene3D G3DSA:1.10.3140.10 6 146 4.8E-55 T 06-07-2017 LK06_RS02785 b934be71c4d13b0ab000742fa3de2eb9 507 Gene3D G3DSA:2.40.110.10 147 266 1.1E-47 T 06-07-2017 LK06_RS02785 b934be71c4d13b0ab000742fa3de2eb9 507 PIRSF PIRSF500125 2 504 1.6E-256 T 06-07-2017 IPR024677 4-HPA 3-monooxygenase large component/Pyoverdin chromophore biosynthetic protein LK06_RS02785 b934be71c4d13b0ab000742fa3de2eb9 507 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 9 274 3.2E-96 T 06-07-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal LK06_RS02785 b934be71c4d13b0ab000742fa3de2eb9 507 PIRSF PIRSF000331 5 494 4.7E-203 T 06-07-2017 IPR004925 HpaB/PvcC/4-BUDH LK06_RS02785 b934be71c4d13b0ab000742fa3de2eb9 507 Gene3D G3DSA:1.20.140.10 267 467 2.2E-36 T 06-07-2017 LK06_RS02785 b934be71c4d13b0ab000742fa3de2eb9 507 SUPERFAMILY SSF56645 7 275 9.16E-84 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS02785 b934be71c4d13b0ab000742fa3de2eb9 507 SUPERFAMILY SSF47203 265 486 2.09E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS02785 b934be71c4d13b0ab000742fa3de2eb9 507 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 283 482 2.3E-65 T 06-07-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 SUPERFAMILY SSF51658 2 386 4.98E-114 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 Pfam PF01261 Xylose isomerase-like TIM barrel 41 265 6.3E-27 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 Hamap MF_00455 Xylose isomerase [xylA]. 1 383 37.574 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 3 384 2.6E-220 T 06-07-2017 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 Gene3D G3DSA:3.20.20.150 4 386 4.5E-138 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 PRINTS PR00688 Xylose isomerase signature 220 247 8.6E-75 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 PRINTS PR00688 Xylose isomerase signature 281 292 8.6E-75 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 PRINTS PR00688 Xylose isomerase signature 82 102 8.6E-75 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 PRINTS PR00688 Xylose isomerase signature 105 124 8.6E-75 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 PRINTS PR00688 Xylose isomerase signature 248 259 8.6E-75 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 PRINTS PR00688 Xylose isomerase signature 129 150 8.6E-75 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 PRINTS PR00688 Xylose isomerase signature 156 175 8.6E-75 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 PRINTS PR00688 Xylose isomerase signature 45 67 8.6E-75 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS29620 5493476dcedd82a435478ca41aba61af 388 PRINTS PR00688 Xylose isomerase signature 178 202 8.6E-75 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 LK06_RS30110 62ca101a3d9a3e0e7ccacf5f23eaa521 275 Pfam PF03476 MOSC N-terminal beta barrel domain 4 115 1.6E-23 T 06-07-2017 IPR005303 MOSC, N-terminal beta barrel LK06_RS30110 62ca101a3d9a3e0e7ccacf5f23eaa521 275 SUPERFAMILY SSF141673 6 134 2.62E-26 T 06-07-2017 LK06_RS30110 62ca101a3d9a3e0e7ccacf5f23eaa521 275 Pfam PF03473 MOSC domain 144 271 3.4E-30 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 LK06_RS30110 62ca101a3d9a3e0e7ccacf5f23eaa521 275 SUPERFAMILY SSF50800 4 52 7.64E-18 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain LK06_RS30110 62ca101a3d9a3e0e7ccacf5f23eaa521 275 SUPERFAMILY SSF50800 153 273 7.64E-18 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain LK06_RS00755 471d5dc5f41783e419bfcd613ce504d9 393 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 170 369 2.5E-40 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS00755 471d5dc5f41783e419bfcd613ce504d9 393 SMART SM00331 143 369 1.9E-33 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS00755 471d5dc5f41783e419bfcd613ce504d9 393 SUPERFAMILY SSF81606 158 365 1.23E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS19835 27001702ee9776a47ba6b624cd2963e0 482 SUPERFAMILY SSF53448 8 261 8.05E-62 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS19835 27001702ee9776a47ba6b624cd2963e0 482 Gene3D G3DSA:3.90.550.10 7 259 3.3E-73 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS19835 27001702ee9776a47ba6b624cd2963e0 482 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 402 437 3.2E-5 T 06-07-2017 IPR001451 Hexapeptide repeat LK06_RS19835 27001702ee9776a47ba6b624cd2963e0 482 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 462 4.2E-166 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 LK06_RS19835 27001702ee9776a47ba6b624cd2963e0 482 SUPERFAMILY SSF51161 257 472 4.42E-42 T 06-07-2017 IPR011004 Trimeric LpxA-like LK06_RS19835 27001702ee9776a47ba6b624cd2963e0 482 Gene3D G3DSA:2.160.10.10 265 446 1.5E-40 T 06-07-2017 LK06_RS19835 27001702ee9776a47ba6b624cd2963e0 482 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 460 39.822 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 LK06_RS19835 27001702ee9776a47ba6b624cd2963e0 482 Pfam PF12804 MobA-like NTP transferase domain 9 139 9.1E-23 T 06-07-2017 IPR025877 MobA-like NTP transferase LK06_RS01120 3ab2e8cd0952e8dec9715aca3a1c930a 463 Gene3D G3DSA:3.30.200.20 7 86 1.0E-20 T 06-07-2017 LK06_RS01120 3ab2e8cd0952e8dec9715aca3a1c930a 463 SMART SM00220 10 260 4.0E-44 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS01120 3ab2e8cd0952e8dec9715aca3a1c930a 463 Pfam PF00069 Protein kinase domain 10 213 4.6E-35 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS01120 3ab2e8cd0952e8dec9715aca3a1c930a 463 SUPERFAMILY SSF56112 6 259 1.18E-57 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS01120 3ab2e8cd0952e8dec9715aca3a1c930a 463 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS01120 3ab2e8cd0952e8dec9715aca3a1c930a 463 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS01120 3ab2e8cd0952e8dec9715aca3a1c930a 463 Gene3D G3DSA:1.10.510.10 87 212 9.1E-32 T 06-07-2017 LK06_RS22400 f5824baa1f29cb53571811335313ac86 335 Gene3D G3DSA:1.25.40.10 21 110 2.2E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22400 f5824baa1f29cb53571811335313ac86 335 SUPERFAMILY SSF48452 19 110 5.06E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS06465 2f5f68c93c02dbfaf887a4e5b20ed387 254 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 245 1.3E-104 T 06-07-2017 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 LK06_RS06465 2f5f68c93c02dbfaf887a4e5b20ed387 254 Pfam PF00005 ABC transporter 23 174 9.6E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS06465 2f5f68c93c02dbfaf887a4e5b20ed387 254 SMART SM00382 32 225 3.9E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS06465 2f5f68c93c02dbfaf887a4e5b20ed387 254 Gene3D G3DSA:3.40.50.300 3 236 1.4E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06465 2f5f68c93c02dbfaf887a4e5b20ed387 254 SUPERFAMILY SSF52540 4 234 1.09E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09565 7d7c89a98a82734f265e1f35fbe4876c 281 Gene3D G3DSA:3.30.1180.10 155 279 5.9E-42 T 06-07-2017 LK06_RS09565 7d7c89a98a82734f265e1f35fbe4876c 281 SUPERFAMILY SSF82549 5 280 2.62E-76 T 06-07-2017 LK06_RS09565 7d7c89a98a82734f265e1f35fbe4876c 281 Gene3D G3DSA:3.40.50.10170 5 150 2.1E-44 T 06-07-2017 LK06_RS09565 7d7c89a98a82734f265e1f35fbe4876c 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 278 2.2E-86 T 06-07-2017 IPR003797 DegV LK06_RS09565 7d7c89a98a82734f265e1f35fbe4876c 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 280 1.5E-86 T 06-07-2017 IPR003797 DegV LK06_RS02330 a914f2313c3f5f132d85e1b391ec934a 211 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 9 201 34.438 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS02330 a914f2313c3f5f132d85e1b391ec934a 211 SUPERFAMILY SSF52096 17 201 2.71E-50 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS02330 a914f2313c3f5f132d85e1b391ec934a 211 Gene3D G3DSA:3.90.226.10 10 198 5.7E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS02330 a914f2313c3f5f132d85e1b391ec934a 211 Pfam PF00574 Clp protease 20 198 1.8E-59 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA LK06_RS02330 a914f2313c3f5f132d85e1b391ec934a 211 PRINTS PR00127 Clp protease catalytic subunit P signature 96 113 1.0E-34 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS02330 a914f2313c3f5f132d85e1b391ec934a 211 PRINTS PR00127 Clp protease catalytic subunit P signature 65 85 1.0E-34 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS02330 a914f2313c3f5f132d85e1b391ec934a 211 PRINTS PR00127 Clp protease catalytic subunit P signature 25 40 1.0E-34 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS02330 a914f2313c3f5f132d85e1b391ec934a 211 PRINTS PR00127 Clp protease catalytic subunit P signature 117 136 1.0E-34 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS02330 a914f2313c3f5f132d85e1b391ec934a 211 PRINTS PR00127 Clp protease catalytic subunit P signature 176 195 1.0E-34 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS03075 05034ee73be2cb0cabe8d967c5fe6ab1 281 SUPERFAMILY SSF53335 27 238 1.1E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03075 05034ee73be2cb0cabe8d967c5fe6ab1 281 Gene3D G3DSA:3.40.50.150 10 265 1.4E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 SUPERFAMILY SSF51735 9 248 2.47E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 5.4E-56 T 06-07-2017 LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 6.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 6.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 6.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 6.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 Gene3D G3DSA:3.40.50.720 5 249 1.1E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 8.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03140 cb393d2202e02b5ec4c6ae22890c0646 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 8.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19620 888abb33af2ee7e64c9ee927f4f51fdb 200 SUPERFAMILY SSF48498 82 193 1.46E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS19620 888abb33af2ee7e64c9ee927f4f51fdb 200 Gene3D G3DSA:1.10.10.60 8 62 2.4E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS19620 888abb33af2ee7e64c9ee927f4f51fdb 200 SUPERFAMILY SSF46689 9 77 2.0E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS19620 888abb33af2ee7e64c9ee927f4f51fdb 200 Gene3D G3DSA:1.10.357.10 63 194 1.7E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS19620 888abb33af2ee7e64c9ee927f4f51fdb 200 Pfam PF16859 Bacterial transcriptional repressor C-terminal 79 190 5.4E-29 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS19620 888abb33af2ee7e64c9ee927f4f51fdb 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 65 1.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS14630 7ebddebe053aa6a91c724c0d3b2dfca0 545 SUPERFAMILY SSF103473 30 225 4.71E-5 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS14630 7ebddebe053aa6a91c724c0d3b2dfca0 545 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 323 336 - T 06-07-2017 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 LK06_RS14630 7ebddebe053aa6a91c724c0d3b2dfca0 545 Pfam PF01564 Spermine/spermidine synthase 271 465 3.8E-28 T 06-07-2017 LK06_RS14630 7ebddebe053aa6a91c724c0d3b2dfca0 545 Gene3D G3DSA:3.40.50.150 301 505 5.9E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS14630 7ebddebe053aa6a91c724c0d3b2dfca0 545 SUPERFAMILY SSF53335 257 468 2.5E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS14630 7ebddebe053aa6a91c724c0d3b2dfca0 545 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 229 536 20.136 T 06-07-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 LK06_RS15445 55ecab6cd4ad294c89328a42b5d9eeaa 334 Pfam PF02779 Transketolase, pyrimidine binding domain 9 182 7.3E-47 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS15445 55ecab6cd4ad294c89328a42b5d9eeaa 334 Gene3D G3DSA:3.40.50.970 7 201 4.4E-74 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS15445 55ecab6cd4ad294c89328a42b5d9eeaa 334 Pfam PF02780 Transketolase, C-terminal domain 200 321 1.4E-37 T 06-07-2017 IPR033248 Transketolase, C-terminal domain LK06_RS15445 55ecab6cd4ad294c89328a42b5d9eeaa 334 SMART SM00861 9 184 8.8E-67 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS15445 55ecab6cd4ad294c89328a42b5d9eeaa 334 Gene3D G3DSA:3.40.50.920 204 325 9.8E-41 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS15445 55ecab6cd4ad294c89328a42b5d9eeaa 334 SUPERFAMILY SSF52922 197 327 3.53E-38 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS15445 55ecab6cd4ad294c89328a42b5d9eeaa 334 SUPERFAMILY SSF52518 8 192 1.61E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS13025 6b5b69060af2f43842fddbeb6cbcb09b 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 55 1.3E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13025 6b5b69060af2f43842fddbeb6cbcb09b 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 11 22 8.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13025 6b5b69060af2f43842fddbeb6cbcb09b 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 8.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13025 6b5b69060af2f43842fddbeb6cbcb09b 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 32 8.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13025 6b5b69060af2f43842fddbeb6cbcb09b 304 Gene3D G3DSA:1.10.10.10 1 77 1.2E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13025 6b5b69060af2f43842fddbeb6cbcb09b 304 Gene3D G3DSA:3.40.190.10 170 254 1.0E-14 T 06-07-2017 LK06_RS13025 6b5b69060af2f43842fddbeb6cbcb09b 304 SUPERFAMILY SSF53850 80 287 4.35E-35 T 06-07-2017 LK06_RS13025 6b5b69060af2f43842fddbeb6cbcb09b 304 SUPERFAMILY SSF46785 2 102 1.13E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13025 6b5b69060af2f43842fddbeb6cbcb09b 304 Pfam PF03466 LysR substrate binding domain 81 283 1.5E-31 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS13025 6b5b69060af2f43842fddbeb6cbcb09b 304 Gene3D G3DSA:3.40.190.10 81 169 9.2E-16 T 06-07-2017 LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 Gene3D G3DSA:3.40.50.1820 455 703 5.6E-79 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 637 659 3.0E-6 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 508 532 3.0E-6 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 566 586 3.0E-6 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 114 407 3.5E-35 T 06-07-2017 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 Pfam PF00326 Prolyl oligopeptidase family 502 704 4.0E-45 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 SUPERFAMILY SSF53474 459 703 2.68E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 SUPERFAMILY SSF82171 20 67 1.96E-30 T 06-07-2017 LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 SUPERFAMILY SSF82171 129 354 1.96E-30 T 06-07-2017 LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 543 573 - T 06-07-2017 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 LK06_RS21910 3c08c00490822c4c9c5054c69a4bd8ad 710 Gene3D G3DSA:2.140.10.30 21 439 1.4E-68 T 06-07-2017 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 PRINTS PR00690 Adhesin family signature 70 83 1.9E-7 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 PRINTS PR00690 Adhesin family signature 204 225 1.9E-7 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 PRINTS PR00690 Adhesin family signature 257 275 1.9E-7 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 Gene3D G3DSA:3.40.50.1980 198 317 3.8E-31 T 06-07-2017 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 Gene3D G3DSA:3.40.50.1980 26 197 5.9E-43 T 06-07-2017 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 SUPERFAMILY SSF53807 38 317 1.28E-68 T 06-07-2017 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 PRINTS PR00691 Adhesin B signature 148 167 1.2E-6 T 06-07-2017 IPR006129 Adhesin B GO:0007155 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 PRINTS PR00691 Adhesin B signature 204 221 1.2E-6 T 06-07-2017 IPR006129 Adhesin B GO:0007155 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 PRINTS PR00691 Adhesin B signature 295 313 1.2E-6 T 06-07-2017 IPR006129 Adhesin B GO:0007155 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 PRINTS PR00691 Adhesin B signature 253 270 1.2E-6 T 06-07-2017 IPR006129 Adhesin B GO:0007155 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 PRINTS PR00691 Adhesin B signature 64 82 1.2E-6 T 06-07-2017 IPR006129 Adhesin B GO:0007155 LK06_RS09295 b80852b741046973b8447cdc60965a61 319 Pfam PF01297 Zinc-uptake complex component A periplasmic 42 315 8.8E-69 T 06-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 LK06_RS05905 b8856e89bfe61512834eb4b159d50a77 262 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 10 247 8.0E-80 T 06-07-2017 LK06_RS06070 92a37dec6f895c365151dd639dea575f 505 SUPERFAMILY SSF52743 148 327 1.44E-76 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS06070 92a37dec6f895c365151dd639dea575f 505 SUPERFAMILY SSF52743 354 504 1.44E-76 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS06070 92a37dec6f895c365151dd639dea575f 505 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 220 230 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site LK06_RS06070 92a37dec6f895c365151dd639dea575f 505 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 426 436 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site LK06_RS06070 92a37dec6f895c365151dd639dea575f 505 Gene3D G3DSA:3.40.50.200 142 504 4.5E-80 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS06070 92a37dec6f895c365151dd639dea575f 505 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 173 184 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site LK06_RS06070 92a37dec6f895c365151dd639dea575f 505 PRINTS PR00723 Subtilisin serine protease family (S8) signature 425 441 1.1E-20 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS06070 92a37dec6f895c365151dd639dea575f 505 PRINTS PR00723 Subtilisin serine protease family (S8) signature 216 229 1.1E-20 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS06070 92a37dec6f895c365151dd639dea575f 505 PRINTS PR00723 Subtilisin serine protease family (S8) signature 168 187 1.1E-20 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS06070 92a37dec6f895c365151dd639dea575f 505 Pfam PF00082 Subtilase family 169 494 5.6E-46 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS06035 075141de4a3a95180dce7239c3ce6db9 94 Pfam PF04226 Transglycosylase associated protein 33 80 1.5E-9 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 LK06_RS15930 9d1fd15d8160b47ee9e19ac0ef9f23b9 573 SUPERFAMILY SSF56112 87 250 1.36E-13 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS15930 9d1fd15d8160b47ee9e19ac0ef9f23b9 573 Gene3D G3DSA:3.30.200.20 64 135 0.001 T 06-07-2017 LK06_RS15930 9d1fd15d8160b47ee9e19ac0ef9f23b9 573 Gene3D G3DSA:2.60.120.260 434 550 1.7E-9 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS15930 9d1fd15d8160b47ee9e19ac0ef9f23b9 573 SUPERFAMILY SSF49785 429 554 1.42E-7 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS15930 9d1fd15d8160b47ee9e19ac0ef9f23b9 573 Gene3D G3DSA:1.10.510.10 136 208 2.3E-8 T 06-07-2017 LK06_RS01105 fd8cda506ac135d4e7459cf2417e8c85 330 Gene3D G3DSA:1.10.10.60 230 276 1.9E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01105 fd8cda506ac135d4e7459cf2417e8c85 330 Pfam PF01965 DJ-1/PfpI family 78 184 2.6E-10 T 06-07-2017 IPR002818 DJ-1/PfpI LK06_RS01105 fd8cda506ac135d4e7459cf2417e8c85 330 SUPERFAMILY SSF46689 223 272 1.97E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01105 fd8cda506ac135d4e7459cf2417e8c85 330 SMART SM00342 239 322 4.6E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS01105 fd8cda506ac135d4e7459cf2417e8c85 330 Pfam PF12833 Helix-turn-helix domain 245 324 1.9E-16 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS01105 fd8cda506ac135d4e7459cf2417e8c85 330 SUPERFAMILY SSF46689 276 325 5.73E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01105 fd8cda506ac135d4e7459cf2417e8c85 330 Gene3D G3DSA:3.40.50.880 16 229 6.0E-41 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS01105 fd8cda506ac135d4e7459cf2417e8c85 330 SUPERFAMILY SSF52317 14 205 5.0E-42 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS01105 fd8cda506ac135d4e7459cf2417e8c85 330 Gene3D G3DSA:1.10.10.60 277 324 2.9E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS17715 06c0f5b4bb652c760d1790a47845e46c 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 6.1E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17715 06c0f5b4bb652c760d1790a47845e46c 206 SUPERFAMILY SSF46689 7 79 1.31E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS17715 06c0f5b4bb652c760d1790a47845e46c 206 Gene3D G3DSA:1.10.10.60 7 59 1.2E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS17715 06c0f5b4bb652c760d1790a47845e46c 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.6E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17715 06c0f5b4bb652c760d1790a47845e46c 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.6E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17715 06c0f5b4bb652c760d1790a47845e46c 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS17715 06c0f5b4bb652c760d1790a47845e46c 206 Gene3D G3DSA:1.10.357.10 60 189 4.2E-8 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS18520 b56008edfbe8c9b4dba87f7759e6bd0d 145 Pfam PF11208 Protein of unknown function (DUF2992) 7 145 9.6E-37 T 06-07-2017 IPR016787 Uncharacterised conserved protein UCP021328 LK06_RS18520 b56008edfbe8c9b4dba87f7759e6bd0d 145 PIRSF PIRSF021328 2 145 4.1E-33 T 06-07-2017 IPR016787 Uncharacterised conserved protein UCP021328 LK06_RS20220 849bd6fab34a806128657f7d7f996a86 101 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 26 99 1.9E-16 T 06-07-2017 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal LK06_RS20220 849bd6fab34a806128657f7d7f996a86 101 SUPERFAMILY SSF48600 24 86 3.51E-10 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS20220 849bd6fab34a806128657f7d7f996a86 101 Gene3D G3DSA:1.20.59.10 17 84 7.3E-11 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS20220 849bd6fab34a806128657f7d7f996a86 101 Pfam PF01817 Chorismate mutase type II 30 82 9.8E-8 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS20220 849bd6fab34a806128657f7d7f996a86 101 SMART SM00830 30 98 1.8E-4 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS25385 602b4c970aa094af8a10367ac0707a55 228 Pfam PF07729 FCD domain 76 197 3.4E-24 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS25385 602b4c970aa094af8a10367ac0707a55 228 Gene3D G3DSA:1.10.10.10 6 67 6.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25385 602b4c970aa094af8a10367ac0707a55 228 SMART SM00895 76 198 1.8E-20 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS25385 602b4c970aa094af8a10367ac0707a55 228 SMART SM00345 8 66 1.3E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS25385 602b4c970aa094af8a10367ac0707a55 228 SUPERFAMILY SSF46785 7 70 1.42E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25385 602b4c970aa094af8a10367ac0707a55 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 5.1E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS25385 602b4c970aa094af8a10367ac0707a55 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 5.1E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS25385 602b4c970aa094af8a10367ac0707a55 228 Gene3D G3DSA:1.20.120.530 69 200 3.0E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS25385 602b4c970aa094af8a10367ac0707a55 228 SUPERFAMILY SSF48008 72 200 1.33E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS25385 602b4c970aa094af8a10367ac0707a55 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 2.8E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS08510 b54a7ff0f749ba0ff1509f4fdf6e1f6a 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 3.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS08510 b54a7ff0f749ba0ff1509f4fdf6e1f6a 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 3.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS08510 b54a7ff0f749ba0ff1509f4fdf6e1f6a 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 4.0E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS08510 b54a7ff0f749ba0ff1509f4fdf6e1f6a 217 Gene3D G3DSA:1.10.357.10 18 201 8.1E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS08510 b54a7ff0f749ba0ff1509f4fdf6e1f6a 217 SUPERFAMILY SSF46689 17 100 1.95E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01990 70ac5a016d29e62b45260607beb36d18 455 Gene3D G3DSA:3.60.15.10 38 276 4.0E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS01990 70ac5a016d29e62b45260607beb36d18 455 SMART SM00849 49 247 2.3E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS01990 70ac5a016d29e62b45260607beb36d18 455 Pfam PF14863 Alkyl sulfatase dimerisation 286 419 3.7E-29 T 06-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 LK06_RS01990 70ac5a016d29e62b45260607beb36d18 455 Pfam PF00753 Metallo-beta-lactamase superfamily 49 247 1.9E-17 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS01990 70ac5a016d29e62b45260607beb36d18 455 SUPERFAMILY SSF56281 34 418 3.93E-84 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS24475 6e85ffa9712a1480361b0fb5fbc5cc8a 391 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 85 299 5.4E-63 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 LK06_RS24475 6e85ffa9712a1480361b0fb5fbc5cc8a 391 SUPERFAMILY SSF102405 93 300 4.43E-37 T 06-07-2017 LK06_RS24475 6e85ffa9712a1480361b0fb5fbc5cc8a 391 Gene3D G3DSA:3.40.50.450 127 269 7.3E-14 T 06-07-2017 LK06_RS24475 6e85ffa9712a1480361b0fb5fbc5cc8a 391 Pfam PF02481 DNA recombination-mediator protein A 86 292 5.8E-69 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 LK06_RS00785 1269eb592785298707ba0c2a01a22a33 323 Gene3D G3DSA:3.90.1720.10 206 310 6.4E-32 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS00785 1269eb592785298707ba0c2a01a22a33 323 Pfam PF00877 NlpC/P60 family 220 308 8.0E-17 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS00785 1269eb592785298707ba0c2a01a22a33 323 SUPERFAMILY SSF54001 203 309 7.36E-31 T 06-07-2017 LK06_RS06490 764fc9cb6d9eb2b45ea84c2625300250 271 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 32 256 4.9E-76 T 06-07-2017 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 LK06_RS06490 764fc9cb6d9eb2b45ea84c2625300250 271 SUPERFAMILY SSF110710 9 260 9.68E-84 T 06-07-2017 LK06_RS01710 51eec3a69196ee16bfc5b0bfc730f473 412 Gene3D G3DSA:3.20.20.80 18 296 6.8E-17 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS01710 51eec3a69196ee16bfc5b0bfc730f473 412 SUPERFAMILY SSF51445 16 326 7.38E-33 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS28130 ede27b295d3be79e90e6596077dce85e 385 Pfam PF12706 Beta-lactamase superfamily domain 149 339 1.1E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS28130 ede27b295d3be79e90e6596077dce85e 385 Gene3D G3DSA:3.60.15.10 116 362 2.6E-74 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS28130 ede27b295d3be79e90e6596077dce85e 385 SUPERFAMILY SSF56281 129 355 3.01E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS15495 8ac80cf4a538bd6291dc5ee25afae315 95 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 6 94 7.5E-44 T 06-07-2017 IPR009359 Phenylacetic acid degradation B LK06_RS15495 8ac80cf4a538bd6291dc5ee25afae315 95 PIRSF PIRSF030200 1 95 9.8E-44 T 06-07-2017 IPR009359 Phenylacetic acid degradation B LK06_RS15495 8ac80cf4a538bd6291dc5ee25afae315 95 Pfam PF06243 Phenylacetic acid degradation B 5 92 4.9E-40 T 06-07-2017 IPR009359 Phenylacetic acid degradation B LK06_RS11880 7d5fc9a1b7c77cda99e39e6cf554b902 128 Pfam PF06262 Zinicin-like metallopeptidase 64 123 1.3E-6 T 06-07-2017 IPR010428 Zinicin-like metallopeptidase LK06_RS11880 7d5fc9a1b7c77cda99e39e6cf554b902 128 SUPERFAMILY SSF55486 14 125 7.32E-23 T 06-07-2017 LK06_RS04765 619956e2e876e8a53eb5541f529609d0 303 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 24 203 1.3E-57 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS04765 619956e2e876e8a53eb5541f529609d0 303 SUPERFAMILY SSF51735 21 203 9.64E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS04765 619956e2e876e8a53eb5541f529609d0 303 PIRSF PIRSF000105 19 303 2.6E-76 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 LK06_RS04765 619956e2e876e8a53eb5541f529609d0 303 SUPERFAMILY SSF48179 206 302 2.47E-30 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS04765 619956e2e876e8a53eb5541f529609d0 303 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 206 302 8.5E-33 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS04765 619956e2e876e8a53eb5541f529609d0 303 Gene3D G3DSA:3.40.50.720 20 207 1.6E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS04765 619956e2e876e8a53eb5541f529609d0 303 Gene3D G3DSA:1.10.1040.10 208 302 2.6E-33 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS29300 e4d4410a740d3a7eeb07d13e78e7c9e0 304 Pfam PF00582 Universal stress protein family 164 302 2.8E-15 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS29300 e4d4410a740d3a7eeb07d13e78e7c9e0 304 Pfam PF00582 Universal stress protein family 3 143 4.1E-25 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS29300 e4d4410a740d3a7eeb07d13e78e7c9e0 304 SUPERFAMILY SSF52402 3 146 4.52E-31 T 06-07-2017 LK06_RS29300 e4d4410a740d3a7eeb07d13e78e7c9e0 304 SUPERFAMILY SSF52402 164 303 4.19E-19 T 06-07-2017 LK06_RS29300 e4d4410a740d3a7eeb07d13e78e7c9e0 304 Gene3D G3DSA:3.40.50.620 1 144 7.9E-34 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS29300 e4d4410a740d3a7eeb07d13e78e7c9e0 304 PRINTS PR01438 Universal stress protein signature 2 20 8.0E-11 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS29300 e4d4410a740d3a7eeb07d13e78e7c9e0 304 PRINTS PR01438 Universal stress protein signature 121 143 8.0E-11 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS29300 e4d4410a740d3a7eeb07d13e78e7c9e0 304 PRINTS PR01438 Universal stress protein signature 103 115 8.0E-11 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS29300 e4d4410a740d3a7eeb07d13e78e7c9e0 304 Gene3D G3DSA:3.40.50.620 162 302 4.1E-21 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS15500 1e5882d0b5b7b594afcb499f68c3e795 239 Pfam PF05138 Phenylacetic acid catabolic protein 9 239 3.7E-72 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 LK06_RS15500 1e5882d0b5b7b594afcb499f68c3e795 239 PIRSF PIRSF037834 2 239 2.8E-88 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 LK06_RS15500 1e5882d0b5b7b594afcb499f68c3e795 239 SUPERFAMILY SSF47240 11 233 3.97E-61 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS15500 1e5882d0b5b7b594afcb499f68c3e795 239 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 13 239 8.9E-74 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 LK06_RS15500 1e5882d0b5b7b594afcb499f68c3e795 239 Gene3D G3DSA:1.20.1260.10 10 239 4.6E-79 T 06-07-2017 IPR012347 Ferritin-related LK06_RS14480 83a91e490ad91a0adcaca0884884e849 223 SUPERFAMILY SSF88659 146 221 3.55E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14480 83a91e490ad91a0adcaca0884884e849 223 SUPERFAMILY SSF88946 64 136 1.02E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14480 83a91e490ad91a0adcaca0884884e849 223 Pfam PF04542 Sigma-70 region 2 71 135 3.2E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14480 83a91e490ad91a0adcaca0884884e849 223 Gene3D G3DSA:1.10.10.10 158 220 2.3E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14480 83a91e490ad91a0adcaca0884884e849 223 Gene3D G3DSA:1.10.1740.10 66 135 1.3E-14 T 06-07-2017 LK06_RS14480 83a91e490ad91a0adcaca0884884e849 223 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 62 221 3.1E-56 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 LK06_RS14480 83a91e490ad91a0adcaca0884884e849 223 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 67 219 4.8E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14480 83a91e490ad91a0adcaca0884884e849 223 Pfam PF08281 Sigma-70, region 4 162 215 2.6E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS11350 f55db639bdefb35531ff2654c48b24b0 599 Gene3D G3DSA:3.40.50.300 28 183 6.7E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11350 f55db639bdefb35531ff2654c48b24b0 599 Pfam PF04851 Type III restriction enzyme, res subunit 29 99 5.9E-7 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 LK06_RS11350 f55db639bdefb35531ff2654c48b24b0 599 Pfam PF04851 Type III restriction enzyme, res subunit 138 180 3.0E-5 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 LK06_RS11350 f55db639bdefb35531ff2654c48b24b0 599 SUPERFAMILY SSF52540 24 184 1.18E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11350 f55db639bdefb35531ff2654c48b24b0 599 SMART SM00487 26 202 9.6E-17 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS11350 f55db639bdefb35531ff2654c48b24b0 599 SUPERFAMILY SSF52540 142 202 7.68E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11350 f55db639bdefb35531ff2654c48b24b0 599 SUPERFAMILY SSF52540 273 392 7.68E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11350 f55db639bdefb35531ff2654c48b24b0 599 Gene3D G3DSA:3.40.50.300 290 415 3.1E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 1.6E-6 T 06-07-2017 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 1.6E-6 T 06-07-2017 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 357 377 1.6E-6 T 06-07-2017 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 201 219 1.6E-6 T 06-07-2017 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 1.6E-6 T 06-07-2017 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 1.6E-6 T 06-07-2017 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 Gene3D G3DSA:1.20.1250.20 261 416 2.8E-24 T 06-07-2017 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 Gene3D G3DSA:1.20.1250.20 3 194 4.3E-32 T 06-07-2017 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 Gene3D G3DSA:1.20.1250.20 466 504 2.8E-24 T 06-07-2017 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 Pfam PF07690 Major Facilitator Superfamily 12 408 7.7E-54 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 417 4.9E-81 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 SUPERFAMILY SSF103473 470 498 5.75E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 SUPERFAMILY SSF103473 247 418 5.75E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08220 426a0ab0cee4265746588780695cdb97 515 SUPERFAMILY SSF103473 2 198 5.75E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS30525 ea597063fb1f8453951a403fb196412b 225 SUPERFAMILY SSF46689 15 80 5.49E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS30525 ea597063fb1f8453951a403fb196412b 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 3.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30525 ea597063fb1f8453951a403fb196412b 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 3.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30525 ea597063fb1f8453951a403fb196412b 225 SUPERFAMILY SSF48498 98 188 2.78E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS30525 ea597063fb1f8453951a403fb196412b 225 Gene3D G3DSA:1.10.357.10 96 219 8.7E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS30525 ea597063fb1f8453951a403fb196412b 225 Gene3D G3DSA:1.10.10.60 15 79 2.0E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS30525 ea597063fb1f8453951a403fb196412b 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 1.0E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30525 ea597063fb1f8453951a403fb196412b 225 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 163 218 6.3E-13 T 06-07-2017 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 PRINTS PR00359 B-class P450 signature 184 206 1.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 PRINTS PR00359 B-class P450 signature 284 311 1.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 PRINTS PR00359 B-class P450 signature 84 95 1.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 PRINTS PR00359 B-class P450 signature 130 146 1.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 PRINTS PR00359 B-class P450 signature 312 327 1.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 PRINTS PR00359 B-class P450 signature 333 342 1.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 PRINTS PR00359 B-class P450 signature 147 162 1.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 PRINTS PR00359 B-class P450 signature 342 353 1.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 PRINTS PR00359 B-class P450 signature 266 277 1.9E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 Pfam PF00067 Cytochrome P450 179 362 3.8E-22 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 SUPERFAMILY SSF48264 7 391 1.44E-96 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 Gene3D G3DSA:1.10.630.10 3 391 1.4E-130 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS27560 3cda0c0be5f81727cc2aa4f8c60c64d7 391 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 335 344 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS08800 0ab876df15607985fc74cac42acb2c4f 247 Gene3D G3DSA:1.10.287.70 120 167 4.9E-15 T 06-07-2017 LK06_RS08800 0ab876df15607985fc74cac42acb2c4f 247 Pfam PF07885 Ion channel 128 204 9.3E-17 T 06-07-2017 IPR013099 Potassium channel domain LK06_RS08800 0ab876df15607985fc74cac42acb2c4f 247 Gene3D G3DSA:1.20.5.110 169 210 5.8E-19 T 06-07-2017 LK06_RS08800 0ab876df15607985fc74cac42acb2c4f 247 SUPERFAMILY SSF81324 38 204 1.93E-37 T 06-07-2017 LK06_RS08800 0ab876df15607985fc74cac42acb2c4f 247 Gene3D G3DSA:1.20.120.350 47 119 1.4E-5 T 06-07-2017 IPR027359 Voltage-dependent channel, four helix bundle domain LK06_RS24580 7718da287c58fe732fdf8ed1a5224c46 479 SUPERFAMILY SSF53720 5 475 1.57E-159 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS24580 7718da287c58fe732fdf8ed1a5224c46 479 Gene3D G3DSA:3.40.605.10 7 263 3.7E-91 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS24580 7718da287c58fe732fdf8ed1a5224c46 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 LK06_RS24580 7718da287c58fe732fdf8ed1a5224c46 479 Gene3D G3DSA:3.40.309.10 264 448 1.8E-63 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS24580 7718da287c58fe732fdf8ed1a5224c46 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 LK06_RS24580 7718da287c58fe732fdf8ed1a5224c46 479 Pfam PF00171 Aldehyde dehydrogenase family 19 473 2.2E-163 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS25200 b5a3d69b6f4191d4044c43c392869303 183 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 76.837 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 LK06_RS25200 b5a3d69b6f4191d4044c43c392869303 183 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 7.2E-45 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 LK06_RS25200 b5a3d69b6f4191d4044c43c392869303 183 Pfam PF03477 ATP cone domain 47 132 2.2E-13 T 06-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 LK06_RS25865 2a2c6b9f3094099094fa2e0da9f4d585 215 SUPERFAMILY SSF102588 11 209 7.06E-32 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 LK06_RS25865 2a2c6b9f3094099094fa2e0da9f4d585 215 Pfam PF02585 GlcNAc-PI de-N-acetylase 14 128 4.6E-13 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 LK06_RS25865 2a2c6b9f3094099094fa2e0da9f4d585 215 Gene3D G3DSA:3.40.50.10320 11 209 3.9E-35 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 LK06_RS19365 9d83dcb6ccef115e13c6190b77fd5dd7 222 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 28 213 1.6E-42 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase LK06_RS19365 9d83dcb6ccef115e13c6190b77fd5dd7 222 SUPERFAMILY SSF100950 27 219 4.05E-42 T 06-07-2017 LK06_RS19365 9d83dcb6ccef115e13c6190b77fd5dd7 222 PIRSF PIRSF006806 25 216 5.8E-32 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase LK06_RS19365 9d83dcb6ccef115e13c6190b77fd5dd7 222 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 28 213 1.1E-37 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase LK06_RS19365 9d83dcb6ccef115e13c6190b77fd5dd7 222 Gene3D G3DSA:3.40.50.10420 27 219 6.1E-51 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 SUPERFAMILY SSF88659 131 189 1.44E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 Gene3D G3DSA:1.10.10.10 129 189 4.1E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 5 322 1.7E-147 T 06-07-2017 IPR014305 RNA polymerase sigma-G type, actinobacteria LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 SUPERFAMILY SSF54427 206 318 1.15E-19 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 Pfam PF02136 Nuclear transport factor 2 (NTF2) domain 207 316 4.9E-9 T 06-07-2017 IPR002075 Nuclear transport factor 2 GO:0005622|GO:0006810 LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 189 2.7E-25 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 Gene3D G3DSA:1.10.1740.10 12 91 4.3E-23 T 06-07-2017 LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 Gene3D G3DSA:3.10.450.50 206 319 4.5E-19 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 Pfam PF08281 Sigma-70, region 4 134 186 8.9E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 SUPERFAMILY SSF88946 11 91 1.69E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20720 150d831f46f27627f83cd5d8b7dbb9dd 337 Pfam PF04542 Sigma-70 region 2 14 77 2.8E-19 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14645 50d5d3150c25eecacc54188c1f3071d2 257 SUPERFAMILY SSF53383 11 257 2.53E-76 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS14645 50d5d3150c25eecacc54188c1f3071d2 257 Gene3D G3DSA:3.40.640.10 49 257 5.8E-72 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS14645 50d5d3150c25eecacc54188c1f3071d2 257 Pfam PF00155 Aminotransferase class I and II 37 257 7.9E-49 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS19940 f580bf2de1281734926c464c32a48ebc 232 Pfam PF06737 Transglycosylase-like domain 41 117 3.3E-35 T 06-07-2017 IPR010618 Transglycosylase-like LK06_RS19940 f580bf2de1281734926c464c32a48ebc 232 Pfam PF01476 LysM domain 185 231 3.5E-10 T 06-07-2017 IPR018392 LysM domain LK06_RS19940 f580bf2de1281734926c464c32a48ebc 232 SUPERFAMILY SSF54106 184 231 4.45E-7 T 06-07-2017 IPR018392 LysM domain LK06_RS19940 f580bf2de1281734926c464c32a48ebc 232 SMART SM00257 184 232 7.1E-10 T 06-07-2017 IPR018392 LysM domain LK06_RS19940 f580bf2de1281734926c464c32a48ebc 232 SUPERFAMILY SSF53955 42 119 9.19E-33 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS19940 f580bf2de1281734926c464c32a48ebc 232 Gene3D G3DSA:3.10.350.10 184 231 1.4E-12 T 06-07-2017 IPR018392 LysM domain LK06_RS19940 f580bf2de1281734926c464c32a48ebc 232 Gene3D G3DSA:1.10.530.10 20 121 3.4E-43 T 06-07-2017 LK06_RS00890 27cc6c4f89bbce7100d431ac0f35c1d6 171 Pfam PF01613 Flavin reductase like domain 27 151 2.0E-18 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS00890 27cc6c4f89bbce7100d431ac0f35c1d6 171 SUPERFAMILY SSF50475 16 156 1.03E-30 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS00890 27cc6c4f89bbce7100d431ac0f35c1d6 171 SMART SM00903 26 164 3.9E-16 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS00890 27cc6c4f89bbce7100d431ac0f35c1d6 171 Gene3D G3DSA:2.30.110.10 19 155 9.9E-35 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS02405 88686405df7bd4307a3824bc719ea8c8 447 SUPERFAMILY SSF56176 363 440 8.72E-16 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS02405 88686405df7bd4307a3824bc719ea8c8 447 Pfam PF03471 Transporter associated domain 364 431 5.8E-16 T 06-07-2017 IPR005170 Transporter-associated domain LK06_RS02405 88686405df7bd4307a3824bc719ea8c8 447 SUPERFAMILY SSF54631 213 347 4.04E-25 T 06-07-2017 LK06_RS02405 88686405df7bd4307a3824bc719ea8c8 447 Pfam PF01595 Domain of unknown function DUF21 9 201 9.3E-32 T 06-07-2017 IPR002550 Domain of unknown function DUF21 LK06_RS02405 88686405df7bd4307a3824bc719ea8c8 447 Gene3D G3DSA:3.10.580.10 209 330 1.6E-15 T 06-07-2017 LK06_RS02405 88686405df7bd4307a3824bc719ea8c8 447 SMART SM01091 357 434 2.9E-17 T 06-07-2017 IPR005170 Transporter-associated domain LK06_RS02405 88686405df7bd4307a3824bc719ea8c8 447 Pfam PF00571 CBS domain 283 335 8.1E-5 T 06-07-2017 IPR000644 CBS domain LK06_RS02405 88686405df7bd4307a3824bc719ea8c8 447 Gene3D G3DSA:3.30.465.10 331 431 1.6E-20 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS30975 a9c37493f19567999dd227833939352d 663 SUPERFAMILY SSF51011 569 631 3.93E-6 T 06-07-2017 LK06_RS30975 a9c37493f19567999dd227833939352d 663 Pfam PF11896 Domain of unknown function (DUF3416) 8 195 7.6E-59 T 06-07-2017 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 LK06_RS30975 a9c37493f19567999dd227833939352d 663 SMART SM00642 201 552 0.0049 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS30975 a9c37493f19567999dd227833939352d 663 SUPERFAMILY SSF51445 202 559 4.65E-79 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS30975 a9c37493f19567999dd227833939352d 663 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 6 652 46.568 T 06-07-2017 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 LK06_RS30975 a9c37493f19567999dd227833939352d 663 Gene3D G3DSA:3.20.20.80 202 557 5.4E-63 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS30975 a9c37493f19567999dd227833939352d 663 Gene3D G3DSA:2.60.40.1180 563 640 4.0E-12 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS04560 6d39ac2f610efb9bf72a5c0c3d0995bb 272 SUPERFAMILY SSF75217 104 266 4.12E-38 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases LK06_RS04560 6d39ac2f610efb9bf72a5c0c3d0995bb 272 Gene3D G3DSA:3.40.1280.10 116 266 1.0E-50 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LK06_RS04560 6d39ac2f610efb9bf72a5c0c3d0995bb 272 Pfam PF00588 SpoU rRNA Methylase family 121 263 1.2E-33 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 LK06_RS04560 6d39ac2f610efb9bf72a5c0c3d0995bb 272 Gene3D G3DSA:3.30.1330.30 7 105 7.0E-16 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like LK06_RS04560 6d39ac2f610efb9bf72a5c0c3d0995bb 272 SUPERFAMILY SSF55315 6 106 5.41E-16 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like LK06_RS30225 6cd4af31fb616c6973043317359d5921 229 Pfam PF01381 Helix-turn-helix 26 81 4.7E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS30225 6cd4af31fb616c6973043317359d5921 229 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 106 225 7.0E-26 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related LK06_RS30225 6cd4af31fb616c6973043317359d5921 229 Gene3D G3DSA:1.10.260.40 22 87 1.2E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS30225 6cd4af31fb616c6973043317359d5921 229 SUPERFAMILY SSF50475 101 225 2.36E-26 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS30225 6cd4af31fb616c6973043317359d5921 229 Gene3D G3DSA:2.30.110.10 96 226 2.4E-42 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS30225 6cd4af31fb616c6973043317359d5921 229 SMART SM00530 25 81 2.3E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS30225 6cd4af31fb616c6973043317359d5921 229 SUPERFAMILY SSF47413 21 81 4.5E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS26045 fd7382095637b44bc1d854b9296e7892 488 Gene3D G3DSA:3.40.50.150 287 459 3.0E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26045 fd7382095637b44bc1d854b9296e7892 488 SUPERFAMILY SSF53335 288 448 3.19E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26045 fd7382095637b44bc1d854b9296e7892 488 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 249 1.2E-109 T 06-07-2017 IPR024740 Hen1, N-terminal LK06_RS26045 fd7382095637b44bc1d854b9296e7892 488 Pfam PF08242 Methyltransferase domain 304 393 9.1E-12 T 06-07-2017 IPR013217 Methyltransferase type 12 LK06_RS26045 fd7382095637b44bc1d854b9296e7892 488 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 3 478 4.7E-201 T 06-07-2017 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial LK06_RS06990 342b14e9586259b3284fc36ab0e71612 283 Pfam PF01144 Coenzyme A transferase 5 209 2.7E-39 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 LK06_RS06990 342b14e9586259b3284fc36ab0e71612 283 Gene3D G3DSA:3.40.1080.10 156 262 3.5E-71 T 06-07-2017 LK06_RS06990 342b14e9586259b3284fc36ab0e71612 283 Gene3D G3DSA:3.40.1080.10 3 117 3.5E-71 T 06-07-2017 LK06_RS06990 342b14e9586259b3284fc36ab0e71612 283 SMART SM00882 5 227 8.3E-39 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 LK06_RS06990 342b14e9586259b3284fc36ab0e71612 283 SUPERFAMILY SSF100950 3 257 8.37E-70 T 06-07-2017 LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 620 40.232 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 SMART SM00861 316 480 3.4E-48 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 SUPERFAMILY SSF52518 309 478 2.06E-49 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 SUPERFAMILY SSF52518 3 345 1.27E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 SUPERFAMILY SSF52922 496 617 1.09E-25 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 Gene3D G3DSA:3.40.50.970 4 188 2.9E-49 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 Gene3D G3DSA:3.40.50.970 236 296 2.9E-49 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 Gene3D G3DSA:3.40.50.920 498 618 7.0E-28 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 7.5E-108 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 Pfam PF02780 Transketolase, C-terminal domain 496 611 5.1E-28 T 06-07-2017 IPR033248 Transketolase, C-terminal domain LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 619 7.9E-183 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 Gene3D G3DSA:3.40.50.970 297 482 5.3E-51 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 Pfam PF02779 Transketolase, pyrimidine binding domain 316 478 1.8E-35 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS28760 b79c7a1136b37b9711feb9057db40395 632 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS32055 3e0a3aa5b4d926c4aa0f26f73ed0f47f 419 Gene3D G3DSA:3.90.1150.10 317 411 1.7E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS32055 3e0a3aa5b4d926c4aa0f26f73ed0f47f 419 Gene3D G3DSA:3.90.1150.10 12 54 1.7E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS32055 3e0a3aa5b4d926c4aa0f26f73ed0f47f 419 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 268 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS32055 3e0a3aa5b4d926c4aa0f26f73ed0f47f 419 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 418 9.4E-138 T 06-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 LK06_RS32055 3e0a3aa5b4d926c4aa0f26f73ed0f47f 419 Pfam PF00202 Aminotransferase class-III 18 410 5.5E-71 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS32055 3e0a3aa5b4d926c4aa0f26f73ed0f47f 419 SUPERFAMILY SSF53383 11 411 1.18E-100 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS32055 3e0a3aa5b4d926c4aa0f26f73ed0f47f 419 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 3 411 1.1E-180 T 06-07-2017 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 LK06_RS32055 3e0a3aa5b4d926c4aa0f26f73ed0f47f 419 Gene3D G3DSA:3.40.640.10 59 309 1.7E-57 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 Gene3D G3DSA:3.40.228.10 145 324 6.0E-51 T 06-07-2017 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 SUPERFAMILY SSF50692 616 740 2.71E-33 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 Gene3D G3DSA:2.40.40.20 605 740 1.2E-30 T 06-07-2017 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 Pfam PF00384 Molybdopterin oxidoreductase 59 436 2.3E-34 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 Gene3D G3DSA:2.20.25.90 7 60 4.4E-12 T 06-07-2017 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 Gene3D G3DSA:3.40.50.740 525 594 4.5E-47 T 06-07-2017 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 Gene3D G3DSA:3.40.50.740 61 136 4.5E-47 T 06-07-2017 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 Gene3D G3DSA:3.40.50.740 325 487 4.5E-47 T 06-07-2017 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 8 49 2.5E-7 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 Pfam PF01568 Molydopterin dinucleotide binding domain 616 735 7.6E-24 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 SMART SM00926 2 55 2.0E-11 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 SUPERFAMILY SSF53706 7 487 7.85E-115 T 06-07-2017 LK06_RS05370 5a714d9f1ec0c280d48334a021b06c87 745 SUPERFAMILY SSF53706 525 624 7.85E-115 T 06-07-2017 LK06_RS23200 3c045af3d3a0efe889824010cb4a5064 381 Gene3D G3DSA:1.10.730.10 276 381 6.5E-22 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS23200 3c045af3d3a0efe889824010cb4a5064 381 Gene3D G3DSA:1.10.730.10 204 224 6.5E-22 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS23200 3c045af3d3a0efe889824010cb4a5064 381 SUPERFAMILY SSF47323 294 381 4.05E-13 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS23200 3c045af3d3a0efe889824010cb4a5064 381 Pfam PF05746 DALR anticodon binding domain 297 381 8.5E-14 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 LK06_RS23200 3c045af3d3a0efe889824010cb4a5064 381 SMART SM01016 4 92 8.4E-16 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS23200 3c045af3d3a0efe889824010cb4a5064 381 Gene3D G3DSA:3.30.1360.70 3 96 1.3E-17 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS23200 3c045af3d3a0efe889824010cb4a5064 381 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 25 92 2.1E-11 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS23200 3c045af3d3a0efe889824010cb4a5064 381 SMART SM00836 210 381 6.0E-13 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 LK06_RS23200 3c045af3d3a0efe889824010cb4a5064 381 SUPERFAMILY SSF55190 24 95 2.35E-13 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 LK06_RS05355 1da916b1ce2ab6b5c6fa4a1d7a940547 308 Pfam PF00892 EamA-like transporter family 15 142 5.6E-16 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS05355 1da916b1ce2ab6b5c6fa4a1d7a940547 308 Pfam PF00892 EamA-like transporter family 155 288 1.0E-22 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS05355 1da916b1ce2ab6b5c6fa4a1d7a940547 308 SUPERFAMILY SSF103481 194 291 7.98E-13 T 06-07-2017 LK06_RS05355 1da916b1ce2ab6b5c6fa4a1d7a940547 308 SUPERFAMILY SSF103481 54 144 4.32E-13 T 06-07-2017 LK06_RS02270 aafda3814c3c5cff8fc37fda16523e34 269 SUPERFAMILY SSF55909 4 269 4.82E-63 T 06-07-2017 LK06_RS02270 aafda3814c3c5cff8fc37fda16523e34 269 Gene3D G3DSA:3.75.10.10 8 268 1.6E-69 T 06-07-2017 LK06_RS02270 aafda3814c3c5cff8fc37fda16523e34 269 Pfam PF02274 Amidinotransferase 15 268 7.5E-22 T 06-07-2017 LK06_RS16165 97f306029bb9e96513ad0f4483c1d3cd 965 Pfam PF12419 SNF2 Helicase protein 327 456 1.3E-38 T 06-07-2017 IPR022138 Helicase SWF/SNF-related LK06_RS16165 97f306029bb9e96513ad0f4483c1d3cd 965 Pfam PF00176 SNF2 family N-terminal domain 520 778 2.3E-49 T 06-07-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 LK06_RS16165 97f306029bb9e96513ad0f4483c1d3cd 965 Gene3D G3DSA:3.40.50.300 494 665 9.6E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16165 97f306029bb9e96513ad0f4483c1d3cd 965 SMART SM00490 823 905 3.5E-26 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS16165 97f306029bb9e96513ad0f4483c1d3cd 965 Pfam PF00271 Helicase conserved C-terminal domain 796 905 1.5E-19 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS16165 97f306029bb9e96513ad0f4483c1d3cd 965 SUPERFAMILY SSF52540 718 961 1.4E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16165 97f306029bb9e96513ad0f4483c1d3cd 965 SMART SM00487 497 679 3.1E-31 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS16165 97f306029bb9e96513ad0f4483c1d3cd 965 SUPERFAMILY SSF52540 481 710 1.18E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16165 97f306029bb9e96513ad0f4483c1d3cd 965 Gene3D G3DSA:3.40.50.300 786 939 6.2E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13110 8e7807aa8daf3c86b67bdbedd39a51d4 184 Gene3D G3DSA:3.40.30.10 2 183 8.4E-45 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS13110 8e7807aa8daf3c86b67bdbedd39a51d4 184 Pfam PF08534 Redoxin 43 169 2.7E-25 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 LK06_RS13110 8e7807aa8daf3c86b67bdbedd39a51d4 184 ProSitePatterns PS00194 Thioredoxin family active site. 68 86 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 LK06_RS13110 8e7807aa8daf3c86b67bdbedd39a51d4 184 SUPERFAMILY SSF52833 42 183 1.26E-36 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS29550 295cce169b9c43dcde6d9bcf4f3064b1 268 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 40 256 1.1E-22 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS29550 295cce169b9c43dcde6d9bcf4f3064b1 268 SUPERFAMILY SSF52266 36 256 7.5E-61 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS29550 295cce169b9c43dcde6d9bcf4f3064b1 268 Gene3D G3DSA:3.40.50.1110 35 257 3.8E-65 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 Gene3D G3DSA:3.40.50.1270 185 391 2.6E-78 T 06-07-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 Gene3D G3DSA:3.40.50.1260 2 184 9.0E-63 T 06-07-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 Pfam PF00162 Phosphoglycerate kinase 12 393 6.0E-143 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 16 26 - T 06-07-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 403 40.521 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 PIRSF PIRSF000724 1 403 1.2E-129 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 PRINTS PR00477 Phosphoglycerate kinase family signature 322 347 1.0E-79 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 PRINTS PR00477 Phosphoglycerate kinase family signature 355 366 1.0E-79 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 1.0E-79 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 1.0E-79 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 1.0E-79 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 1.0E-79 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 PRINTS PR00477 Phosphoglycerate kinase family signature 379 396 1.0E-79 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 1.0E-79 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 1.0E-79 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS06620 e106c8f2399ceb6b05df0e401361e36d 403 SUPERFAMILY SSF53748 4 403 3.77E-140 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS19645 1df3babdce6219f9f5222d569f5ca5bf 148 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 15 145 4.9E-51 T 06-07-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 LK06_RS19645 1df3babdce6219f9f5222d569f5ca5bf 148 Gene3D G3DSA:2.20.25.10 12 55 1.5E-19 T 06-07-2017 LK06_RS19645 1df3babdce6219f9f5222d569f5ca5bf 148 Pfam PF02566 OsmC-like protein 49 145 2.7E-16 T 06-07-2017 IPR003718 OsmC/Ohr family LK06_RS19645 1df3babdce6219f9f5222d569f5ca5bf 148 SUPERFAMILY SSF82784 9 145 1.7E-41 T 06-07-2017 IPR003718 OsmC/Ohr family LK06_RS19645 1df3babdce6219f9f5222d569f5ca5bf 148 Gene3D G3DSA:3.30.300.20 56 145 6.9E-32 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM00823 Phosphopantetheine attachment site 3299 3371 1.2E-25 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM00823 Phosphopantetheine attachment site 1623 1695 1.0E-30 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF00698 Acyl transferase domain 567 876 6.1E-55 T 06-07-2017 IPR014043 Acyl transferase LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF00698 Acyl transferase domain 2240 2549 3.2E-54 T 06-07-2017 IPR014043 Acyl transferase LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.40.47.10 1713 1966 8.4E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.40.47.10 29 296 6.1E-93 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1650 1665 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF52151 566 691 3.66E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF52151 755 852 3.66E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF47336 3292 3377 1.2E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3326 3341 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM00826 2589 2750 2.5E-63 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM00826 923 1089 1.8E-71 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.40.50.720 3026 3204 1.0E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.40.50.720 1351 1552 2.2E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 533 2.2E-12 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2080 2206 6.0E-9 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1867 1883 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF08990 Erythronolide synthase docking 2 27 6.7E-10 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF47336 1617 1730 1.07E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF55048 2363 2427 1.7E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.30.70.250 690 753 2.0E-6 T 06-07-2017 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.30.70.250 2363 2426 2.0E-6 T 06-07-2017 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF101173 3 31 1.83E-5 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:1.10.1200.10 3296 3371 2.4E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:1.10.1200.10 1621 1695 4.1E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1962 2077 3.6E-45 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 5.1E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1351 1527 1.4E-48 T 06-07-2017 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3026 3202 1.2E-48 T 06-07-2017 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF52151 2428 2525 1.57E-60 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF52151 2239 2364 1.57E-60 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF51735 1350 1554 2.58E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF51735 1203 1338 1.33E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF14765 Polyketide synthase dehydratase 2589 2858 2.5E-45 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF14765 Polyketide synthase dehydratase 923 1194 2.6E-54 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF08659 KR domain 3027 3200 2.3E-54 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF08659 KR domain 1351 1525 5.8E-54 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF53901 1711 2076 1.92E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM00825 Beta-ketoacyl synthase 1717 2129 6.5E-220 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM00825 Beta-ketoacyl synthase 36 460 1.3E-219 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1715 1954 9.1E-85 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.0E-90 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF00550 Phosphopantetheine attachment site 1625 1691 4.8E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Pfam PF00550 Phosphopantetheine attachment site 3302 3367 3.7E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF53901 29 404 4.93E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2241 2532 4.6E-96 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 568 859 3.8E-97 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF51735 3024 3228 2.76E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF51735 2890 3010 2.44E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SUPERFAMILY SSF55048 690 754 1.7E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.40.366.10 2427 2536 4.4E-64 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.40.366.10 565 685 1.1E-64 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.40.366.10 754 863 1.1E-64 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.40.366.10 2238 2358 4.4E-64 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.40.47.10 1967 2128 5.2E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 Gene3D G3DSA:3.40.47.10 297 459 6.2E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM01294 3300 3367 4.0E-4 T 06-07-2017 LK06_RS29415 8d83a5c40b9eeefccfc64bfd3aae3e82 3449 SMART SM01294 1624 1691 4.2E-6 T 06-07-2017 LK06_RS27690 f1eb25854e3aec9a89219abb10f8b554 355 SMART SM00421 284 344 0.0016 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS27690 f1eb25854e3aec9a89219abb10f8b554 355 SUPERFAMILY SSF46894 296 351 3.74E-8 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS27690 f1eb25854e3aec9a89219abb10f8b554 355 Gene3D G3DSA:1.10.10.10 289 351 4.8E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27690 f1eb25854e3aec9a89219abb10f8b554 355 Pfam PF13384 Homeodomain-like domain 290 326 2.7E-6 T 06-07-2017 LK06_RS12435 df58545c2f5a1325eb7cb6f0df0cab3d 129 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 63 129 1.5E-27 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12435 df58545c2f5a1325eb7cb6f0df0cab3d 129 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 129 2.3E-44 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12435 df58545c2f5a1325eb7cb6f0df0cab3d 129 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 129 22.681 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12435 df58545c2f5a1325eb7cb6f0df0cab3d 129 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 54 3.8E-17 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12435 df58545c2f5a1325eb7cb6f0df0cab3d 129 SUPERFAMILY SSF54736 58 129 1.46E-22 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like LK06_RS12435 df58545c2f5a1325eb7cb6f0df0cab3d 129 Gene3D G3DSA:1.20.5.710 3 56 1.6E-17 T 06-07-2017 LK06_RS12435 df58545c2f5a1325eb7cb6f0df0cab3d 129 SUPERFAMILY SSF48300 5 65 1.07E-13 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12435 df58545c2f5a1325eb7cb6f0df0cab3d 129 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 102 9.0E-15 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12435 df58545c2f5a1325eb7cb6f0df0cab3d 129 Gene3D G3DSA:3.30.1390.10 57 129 2.3E-30 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like LK06_RS16290 a3a69b8728bdba49277005470ea379d0 486 Gene3D G3DSA:3.40.350.10 55 222 1.6E-36 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal LK06_RS16290 a3a69b8728bdba49277005470ea379d0 486 Gene3D G3DSA:3.90.230.10 223 481 7.5E-69 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS16290 a3a69b8728bdba49277005470ea379d0 486 SUPERFAMILY SSF53092 52 218 2.35E-26 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal LK06_RS16290 a3a69b8728bdba49277005470ea379d0 486 Pfam PF05195 Aminopeptidase P, N-terminal domain 59 177 3.1E-19 T 06-07-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 LK06_RS16290 a3a69b8728bdba49277005470ea379d0 486 SUPERFAMILY SSF55920 219 482 4.45E-68 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS16290 a3a69b8728bdba49277005470ea379d0 486 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 394 406 - T 06-07-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site LK06_RS16290 a3a69b8728bdba49277005470ea379d0 486 Pfam PF00557 Metallopeptidase family M24 226 460 8.0E-50 T 06-07-2017 IPR000994 Peptidase M24, structural domain LK06_RS16290 a3a69b8728bdba49277005470ea379d0 486 SMART SM01011 52 192 3.4E-37 T 06-07-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 LK06_RS06655 e3700e2ad810e95d3e781e9a51705895 140 Pfam PF00355 Rieske [2Fe-2S] domain 45 126 1.7E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS06655 e3700e2ad810e95d3e781e9a51705895 140 SUPERFAMILY SSF50022 4 136 7.59E-28 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS06655 e3700e2ad810e95d3e781e9a51705895 140 PRINTS PR00162 Rieske 2Fe-2S subunit signature 97 109 2.4E-5 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 LK06_RS06655 e3700e2ad810e95d3e781e9a51705895 140 PRINTS PR00162 Rieske 2Fe-2S subunit signature 77 88 2.4E-5 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 LK06_RS06655 e3700e2ad810e95d3e781e9a51705895 140 PRINTS PR00162 Rieske 2Fe-2S subunit signature 110 122 2.4E-5 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 LK06_RS06655 e3700e2ad810e95d3e781e9a51705895 140 Gene3D G3DSA:2.102.10.10 5 135 1.0E-27 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS20620 81fb3961c4b43f022fe9c01ac32a20cb 417 SUPERFAMILY SSF53448 14 240 3.07E-51 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS20620 81fb3961c4b43f022fe9c01ac32a20cb 417 Pfam PF02348 Cytidylyltransferase 17 146 1.9E-23 T 06-07-2017 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 LK06_RS20620 81fb3961c4b43f022fe9c01ac32a20cb 417 Pfam PF08282 haloacid dehalogenase-like hydrolase 332 395 2.6E-8 T 06-07-2017 IPR023214 HAD-like domain LK06_RS20620 81fb3961c4b43f022fe9c01ac32a20cb 417 Gene3D G3DSA:3.90.550.10 13 240 5.5E-75 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS20620 81fb3961c4b43f022fe9c01ac32a20cb 417 SUPERFAMILY SSF56784 256 405 9.11E-33 T 06-07-2017 IPR023214 HAD-like domain LK06_RS20620 81fb3961c4b43f022fe9c01ac32a20cb 417 Gene3D G3DSA:3.40.50.1000 251 404 2.4E-33 T 06-07-2017 IPR023214 HAD-like domain LK06_RS01735 da0f9f6419c58b480e7736f6b7294d4a 450 Pfam PF01425 Amidase 25 428 9.6E-81 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS01735 da0f9f6419c58b480e7736f6b7294d4a 450 Gene3D G3DSA:3.90.1300.10 7 443 3.0E-105 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS01735 da0f9f6419c58b480e7736f6b7294d4a 450 SUPERFAMILY SSF75304 5 437 1.23E-105 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS20725 1967c2698d15f6673fad698d4447520e 427 ProSitePatterns PS00216 Sugar transport proteins signature 1. 91 107 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LK06_RS20725 1967c2698d15f6673fad698d4447520e 427 SUPERFAMILY SSF103473 20 413 3.53E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS20725 1967c2698d15f6673fad698d4447520e 427 Gene3D G3DSA:1.20.1250.20 38 216 6.0E-27 T 06-07-2017 LK06_RS20725 1967c2698d15f6673fad698d4447520e 427 Gene3D G3DSA:1.20.1250.20 240 410 7.9E-11 T 06-07-2017 LK06_RS20725 1967c2698d15f6673fad698d4447520e 427 Pfam PF07690 Major Facilitator Superfamily 41 377 3.1E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS27725 ef930d0a1a27fe6c980e8047aad050f4 606 Gene3D G3DSA:1.20.1560.10 16 325 1.2E-49 T 06-07-2017 LK06_RS27725 ef930d0a1a27fe6c980e8047aad050f4 606 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS27725 ef930d0a1a27fe6c980e8047aad050f4 606 Gene3D G3DSA:3.40.50.300 360 590 4.9E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27725 ef930d0a1a27fe6c980e8047aad050f4 606 SMART SM00382 386 571 4.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS27725 ef930d0a1a27fe6c980e8047aad050f4 606 SUPERFAMILY SSF52540 359 596 3.79E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27725 ef930d0a1a27fe6c980e8047aad050f4 606 Pfam PF00664 ABC transporter transmembrane region 32 296 3.6E-31 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS27725 ef930d0a1a27fe6c980e8047aad050f4 606 Pfam PF00005 ABC transporter 378 526 1.9E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS27725 ef930d0a1a27fe6c980e8047aad050f4 606 SUPERFAMILY SSF90123 9 325 4.19E-52 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS29830 27c7d90915df23c438e47883226d4567 226 Gene3D G3DSA:3.40.470.10 73 225 7.1E-40 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS29830 27c7d90915df23c438e47883226d4567 226 SUPERFAMILY SSF52141 72 225 6.54E-37 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS30850 5c1bafcac1208d560e301c41322c9724 538 SUPERFAMILY SSF56112 65 257 1.33E-31 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS30850 5c1bafcac1208d560e301c41322c9724 538 Gene3D G3DSA:1.10.510.10 81 263 4.6E-28 T 06-07-2017 LK06_RS30850 5c1bafcac1208d560e301c41322c9724 538 SMART SM00220 18 270 1.2E-9 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS30850 5c1bafcac1208d560e301c41322c9724 538 Pfam PF00069 Protein kinase domain 72 229 1.4E-17 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS24815 aa042089840482e2e61954ade8ed0416 415 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 281 291 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site LK06_RS24815 aa042089840482e2e61954ade8ed0416 415 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 57 406 2.1E-93 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 LK06_RS24815 aa042089840482e2e61954ade8ed0416 415 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 72 83 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site LK06_RS24815 aa042089840482e2e61954ade8ed0416 415 SUPERFAMILY SSF52743 49 339 7.59E-78 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS24815 aa042089840482e2e61954ade8ed0416 415 PRINTS PR00723 Subtilisin serine protease family (S8) signature 119 132 3.2E-19 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS24815 aa042089840482e2e61954ade8ed0416 415 PRINTS PR00723 Subtilisin serine protease family (S8) signature 67 86 3.2E-19 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS24815 aa042089840482e2e61954ade8ed0416 415 PRINTS PR00723 Subtilisin serine protease family (S8) signature 280 296 3.2E-19 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS24815 aa042089840482e2e61954ade8ed0416 415 Pfam PF00082 Subtilase family 67 330 3.1E-45 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS24815 aa042089840482e2e61954ade8ed0416 415 Gene3D G3DSA:3.40.50.200 40 338 1.7E-78 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS24815 aa042089840482e2e61954ade8ed0416 415 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 123 133 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site LK06_RS00475 28bc20dcd8de5c978a5e5963c41bb662 492 PIRSF PIRSF012666 1 492 8.3E-230 T 06-07-2017 IPR016602 Uncharacterised conserved protein UCP012666 LK06_RS00475 28bc20dcd8de5c978a5e5963c41bb662 492 SUPERFAMILY SSF55931 37 455 2.75E-57 T 06-07-2017 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 Gene3D G3DSA:1.10.630.10 12 408 6.0E-111 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 Pfam PF00067 Cytochrome P450 209 378 3.4E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 SUPERFAMILY SSF48264 15 408 7.99E-85 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 PRINTS PR00359 B-class P450 signature 298 325 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 PRINTS PR00359 B-class P450 signature 162 177 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 PRINTS PR00359 B-class P450 signature 280 291 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 PRINTS PR00359 B-class P450 signature 348 357 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 PRINTS PR00359 B-class P450 signature 99 110 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 PRINTS PR00359 B-class P450 signature 357 368 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 PRINTS PR00359 B-class P450 signature 200 222 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS07995 259438b7b0e87186737fbe824e917be9 413 PRINTS PR00359 B-class P450 signature 145 161 1.3E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS13140 495ddb1c31d47087c0702ca41219abbc 243 Gene3D G3DSA:1.10.443.10 5 199 2.8E-29 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS13140 495ddb1c31d47087c0702ca41219abbc 243 Pfam PF00589 Phage integrase family 5 185 4.3E-16 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS13140 495ddb1c31d47087c0702ca41219abbc 243 SUPERFAMILY SSF56349 6 194 6.18E-25 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS30025 24559cef9c241ddf596aa50d99415858 294 Gene3D G3DSA:3.20.20.70 3 289 1.9E-80 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS30025 24559cef9c241ddf596aa50d99415858 294 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 289 6.5E-77 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LK06_RS30025 24559cef9c241ddf596aa50d99415858 294 SUPERFAMILY SSF51569 2 290 3.08E-76 T 06-07-2017 LK06_RS30025 24559cef9c241ddf596aa50d99415858 294 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 285 1.4E-66 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LK06_RS30025 24559cef9c241ddf596aa50d99415858 294 PIRSF PIRSF001359 1 293 5.7E-68 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 SUPERFAMILY SSF55785 115 238 3.84E-14 T 06-07-2017 IPR000014 PAS domain LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 SUPERFAMILY SSF55785 15 121 1.15E-21 T 06-07-2017 IPR000014 PAS domain LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 Gene3D G3DSA:3.30.450.40 258 441 1.7E-35 T 06-07-2017 IPR029016 GAF domain-like LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 SMART SM00091 1 68 1.9E-8 T 06-07-2017 IPR000014 PAS domain LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 SMART SM00091 123 189 8.6E-4 T 06-07-2017 IPR000014 PAS domain LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 120 1.9E-15 T 06-07-2017 IPR000014 PAS domain LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 127 243 1.1E-9 T 06-07-2017 IPR000014 PAS domain LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 Pfam PF08448 PAS fold 130 242 1.2E-24 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 SUPERFAMILY SSF81606 474 672 2.07E-11 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 SMART SM00331 462 673 7.3E-35 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 492 673 7.4E-46 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 SMART SM00065 289 444 1.4E-5 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 SUPERFAMILY SSF55781 339 446 6.98E-18 T 06-07-2017 IPR029016 GAF domain-like LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 Gene3D G3DSA:3.30.450.20 117 240 1.3E-20 T 06-07-2017 LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 Pfam PF00989 PAS fold 7 108 1.5E-12 T 06-07-2017 IPR013767 PAS fold GO:0006355 LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 Pfam PF01590 GAF domain 332 434 3.5E-12 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS30435 49265cde429d4f87fba3f04076470bac 677 Gene3D G3DSA:3.30.450.20 6 111 3.8E-20 T 06-07-2017 LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 SMART SM00642 183 594 7.7E-9 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 Pfam PF00128 Alpha amylase, catalytic domain 213 323 2.4E-7 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 Gene3D G3DSA:3.20.20.80 178 603 1.8E-123 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 Gene3D G3DSA:2.60.40.1180 614 725 4.1E-22 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 SUPERFAMILY SSF51445 524 602 2.15E-134 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 SUPERFAMILY SSF51445 158 495 2.15E-134 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 SUPERFAMILY SSF51011 615 725 3.31E-17 T 06-07-2017 LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 SUPERFAMILY SSF81296 16 172 1.08E-36 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 17 725 0.0 T 06-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 22 112 2.6E-19 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS23685 b4c4e7d6856f598405807601e2f44d9e 727 Gene3D G3DSA:2.60.40.10 16 177 1.5E-47 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS08280 eeeec5fca7930609a5e0cbb555b7b40d 215 PIRSF PIRSF000343 1 215 1.8E-67 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 LK06_RS08280 eeeec5fca7930609a5e0cbb555b7b40d 215 Gene3D G3DSA:1.20.910.10 2 208 5.2E-62 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 LK06_RS08280 eeeec5fca7930609a5e0cbb555b7b40d 215 PRINTS PR00088 Haem oxygenase signature 3 28 1.3E-30 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 LK06_RS08280 eeeec5fca7930609a5e0cbb555b7b40d 215 PRINTS PR00088 Haem oxygenase signature 38 63 1.3E-30 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 LK06_RS08280 eeeec5fca7930609a5e0cbb555b7b40d 215 PRINTS PR00088 Haem oxygenase signature 63 88 1.3E-30 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 LK06_RS08280 eeeec5fca7930609a5e0cbb555b7b40d 215 PRINTS PR00088 Haem oxygenase signature 160 181 1.3E-30 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 LK06_RS08280 eeeec5fca7930609a5e0cbb555b7b40d 215 PRINTS PR00088 Haem oxygenase signature 116 137 1.3E-30 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 LK06_RS08280 eeeec5fca7930609a5e0cbb555b7b40d 215 PRINTS PR00088 Haem oxygenase signature 192 210 1.3E-30 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 LK06_RS08280 eeeec5fca7930609a5e0cbb555b7b40d 215 Pfam PF01126 Heme oxygenase 3 205 1.3E-63 T 06-07-2017 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 LK06_RS08280 eeeec5fca7930609a5e0cbb555b7b40d 215 SUPERFAMILY SSF48613 3 209 3.66E-57 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 LK06_RS26315 9df04d7f265edf55419d006025c957c0 131 SUPERFAMILY SSF51182 10 114 6.53E-9 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS26315 9df04d7f265edf55419d006025c957c0 131 Gene3D G3DSA:2.60.120.10 60 112 4.5E-6 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 2.5E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 Pfam PF00072 Response regulator receiver domain 26 116 2.2E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 SUPERFAMILY SSF52172 18 122 1.85E-11 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 SUPERFAMILY SSF46894 144 218 1.46E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 SMART SM00421 155 212 1.0E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 Gene3D G3DSA:3.40.50.2300 20 117 3.0E-9 T 06-07-2017 LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26610 51ea9db2477355186660c15eb71158b7 219 Gene3D G3DSA:1.10.10.10 141 217 1.2E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS10220 13b5ca19a5f7d47eab232b9fc4019ecd 636 Pfam PF01926 50S ribosome-binding GTPase 151 273 2.9E-7 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS10220 13b5ca19a5f7d47eab232b9fc4019ecd 636 Gene3D G3DSA:3.40.50.300 138 348 6.8E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10220 13b5ca19a5f7d47eab232b9fc4019ecd 636 SUPERFAMILY SSF52540 142 349 5.72E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.6E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.6E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.6E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.8E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 3.8E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.8E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 3.8E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.8E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 194 2.1E-5 T 06-07-2017 LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 SUPERFAMILY SSF51735 11 270 1.33E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 Gene3D G3DSA:3.40.50.720 9 231 4.7E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS01920 3e4411d00f6e27f5e888de120b110e58 307 Pfam PF00106 short chain dehydrogenase 16 200 6.6E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28470 e7d0ec421579881748415be34b96e5d5 361 SUPERFAMILY SSF54001 26 177 4.58E-23 T 06-07-2017 LK06_RS28470 e7d0ec421579881748415be34b96e5d5 361 Pfam PF00877 NlpC/P60 family 44 167 6.7E-16 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS28470 e7d0ec421579881748415be34b96e5d5 361 Gene3D G3DSA:3.90.1720.10 28 177 4.8E-29 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS30535 3bdcbd0c901f6a5740211866cf145bc4 634 Gene3D G3DSA:2.30.38.10 425 501 1.2E-11 T 06-07-2017 LK06_RS30535 3bdcbd0c901f6a5740211866cf145bc4 634 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 11 65 2.8E-20 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 LK06_RS30535 3bdcbd0c901f6a5740211866cf145bc4 634 Gene3D G3DSA:3.30.300.30 503 606 1.6E-21 T 06-07-2017 LK06_RS30535 3bdcbd0c901f6a5740211866cf145bc4 634 Gene3D G3DSA:3.40.50.980 249 413 6.4E-26 T 06-07-2017 LK06_RS30535 3bdcbd0c901f6a5740211866cf145bc4 634 SUPERFAMILY SSF56801 11 630 3.14E-155 T 06-07-2017 LK06_RS30535 3bdcbd0c901f6a5740211866cf145bc4 634 Pfam PF13193 AMP-binding enzyme C-terminal domain 518 596 4.8E-23 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS30535 3bdcbd0c901f6a5740211866cf145bc4 634 Gene3D G3DSA:3.40.50.980 61 248 9.7E-38 T 06-07-2017 LK06_RS30535 3bdcbd0c901f6a5740211866cf145bc4 634 ProSitePatterns PS00455 Putative AMP-binding domain signature. 244 255 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS30535 3bdcbd0c901f6a5740211866cf145bc4 634 Pfam PF00501 AMP-binding enzyme 71 508 8.1E-82 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS20685 c44a3d0241e4dc71d265a2ebaab6b961 519 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS20685 c44a3d0241e4dc71d265a2ebaab6b961 519 Pfam PF00005 ABC transporter 27 171 2.7E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS20685 c44a3d0241e4dc71d265a2ebaab6b961 519 Pfam PF00005 ABC transporter 279 435 6.6E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS20685 c44a3d0241e4dc71d265a2ebaab6b961 519 SUPERFAMILY SSF52540 10 228 1.16E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20685 c44a3d0241e4dc71d265a2ebaab6b961 519 SUPERFAMILY SSF52540 259 495 3.16E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20685 c44a3d0241e4dc71d265a2ebaab6b961 519 Gene3D G3DSA:3.40.50.300 8 230 1.9E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20685 c44a3d0241e4dc71d265a2ebaab6b961 519 Gene3D G3DSA:3.40.50.300 258 500 4.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20685 c44a3d0241e4dc71d265a2ebaab6b961 519 SMART SM00382 288 484 3.9 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS20685 c44a3d0241e4dc71d265a2ebaab6b961 519 SMART SM00382 34 219 7.4E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS22010 c47ff7c3d6adff15455893ce66cafb0f 267 SUPERFAMILY SSF52096 2 266 7.01E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS22010 c47ff7c3d6adff15455893ce66cafb0f 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 LK06_RS22010 c47ff7c3d6adff15455893ce66cafb0f 267 Gene3D G3DSA:3.90.226.10 2 264 1.1E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS22010 c47ff7c3d6adff15455893ce66cafb0f 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 265 5.1E-55 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS03860 85ef397777dcbd6e246a66c466fd20f1 535 Gene3D G3DSA:3.20.20.140 191 464 1.4E-35 T 06-07-2017 LK06_RS03860 85ef397777dcbd6e246a66c466fd20f1 535 Pfam PF07969 Amidohydrolase family 55 530 9.9E-104 T 06-07-2017 IPR013108 Amidohydrolase 3 LK06_RS03860 85ef397777dcbd6e246a66c466fd20f1 535 SUPERFAMILY SSF51556 66 127 3.94E-40 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS03860 85ef397777dcbd6e246a66c466fd20f1 535 SUPERFAMILY SSF51556 189 464 3.94E-40 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS03860 85ef397777dcbd6e246a66c466fd20f1 535 Gene3D G3DSA:2.30.40.10 7 108 1.7E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS03860 85ef397777dcbd6e246a66c466fd20f1 535 SUPERFAMILY SSF51338 11 67 5.28E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS03860 85ef397777dcbd6e246a66c466fd20f1 535 SUPERFAMILY SSF51338 466 505 5.28E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS05945 e1407460c0d051a8cced41f510b69a4d 407 Gene3D G3DSA:3.30.70.260 16 92 9.8E-15 T 06-07-2017 LK06_RS05945 e1407460c0d051a8cced41f510b69a4d 407 Gene3D G3DSA:3.30.70.260 119 187 6.5E-4 T 06-07-2017 LK06_RS05945 e1407460c0d051a8cced41f510b69a4d 407 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 174 391 4.2E-77 T 06-07-2017 LK06_RS05945 e1407460c0d051a8cced41f510b69a4d 407 Gene3D G3DSA:3.40.50.1000 250 381 2.1E-46 T 06-07-2017 IPR023214 HAD-like domain LK06_RS05945 e1407460c0d051a8cced41f510b69a4d 407 Gene3D G3DSA:1.10.150.210 198 249 8.6E-25 T 06-07-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 LK06_RS05945 e1407460c0d051a8cced41f510b69a4d 407 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 188 358 1.2E-28 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 LK06_RS05945 e1407460c0d051a8cced41f510b69a4d 407 Pfam PF13740 ACT domain 16 89 1.0E-15 T 06-07-2017 LK06_RS05945 e1407460c0d051a8cced41f510b69a4d 407 Pfam PF12710 haloacid dehalogenase-like hydrolase 189 356 2.2E-22 T 06-07-2017 LK06_RS05945 e1407460c0d051a8cced41f510b69a4d 407 SUPERFAMILY SSF56784 187 394 2.13E-48 T 06-07-2017 IPR023214 HAD-like domain LK06_RS05945 e1407460c0d051a8cced41f510b69a4d 407 SUPERFAMILY SSF55021 16 88 3.79E-8 T 06-07-2017 LK06_RS13900 4e5fe06353e6722c923f473f6a713102 256 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 109 159 6.0E-9 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS13900 4e5fe06353e6722c923f473f6a713102 256 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 185 229 1.7E-11 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS13900 4e5fe06353e6722c923f473f6a713102 256 SUPERFAMILY SSF81923 97 231 4.61E-25 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS13900 4e5fe06353e6722c923f473f6a713102 256 Gene3D G3DSA:1.10.1780.10 95 231 1.1E-35 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS24605 de96cf22bd0aa53b808cd8b9e2ccebe6 356 Pfam PF00962 Adenosine/AMP deaminase 24 343 3.3E-95 T 06-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 LK06_RS24605 de96cf22bd0aa53b808cd8b9e2ccebe6 356 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 24 345 1.4E-81 T 06-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 LK06_RS24605 de96cf22bd0aa53b808cd8b9e2ccebe6 356 SUPERFAMILY SSF51556 19 349 5.3E-76 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS24605 de96cf22bd0aa53b808cd8b9e2ccebe6 356 Gene3D G3DSA:3.20.20.140 20 348 7.9E-96 T 06-07-2017 LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 Pfam PF00270 DEAD/DEAH box helicase 88 234 8.1E-6 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 SMART SM00847 466 561 1.9E-37 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 623 708 5.8E-15 T 06-07-2017 IPR011709 Domain of unknown function DUF1605 LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 15 1314 0.0 T 06-07-2017 IPR010222 RNA helicase HrpA GO:0004004 LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 Pfam PF11898 Domain of unknown function (DUF3418) 722 1314 3.2E-229 T 06-07-2017 IPR024590 RNA helicase HrpA, C-terminal LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 Gene3D G3DSA:3.40.50.300 76 234 1.3E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 Pfam PF04408 Helicase associated domain (HA2) 468 559 1.5E-17 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 Gene3D G3DSA:3.40.50.300 274 418 1.4E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 SMART SM00490 306 406 8.3E-14 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 Pfam PF00271 Helicase conserved C-terminal domain 289 405 2.0E-9 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 SUPERFAMILY SSF52540 74 603 6.99E-111 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 SMART SM00487 68 260 6.3E-26 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS17080 25e9ab462766c04997acfc4aa49a559c 1318 SMART SM00382 92 386 2.5E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 Pfam PF00455 DeoR C terminal sensor domain 93 248 7.6E-43 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 54 72 2.9E-6 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 54 2.9E-6 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 SUPERFAMILY SSF46785 19 78 7.02E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 Pfam PF08220 DeoR-like helix-turn-helix domain 22 74 1.6E-11 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 SMART SM00420 22 74 1.9E-10 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 Gene3D G3DSA:1.10.10.10 17 72 8.5E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 SMART SM01134 89 249 1.8E-52 T 06-07-2017 LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 Gene3D G3DSA:3.40.50.1360 92 231 4.3E-6 T 06-07-2017 LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 SUPERFAMILY SSF100950 93 250 4.5E-22 T 06-07-2017 LK06_RS31635 7f2fecf5576b5f8ca3a92798596f0d46 273 ProSitePatterns PS00894 DeoR-type HTH domain signature. 22 56 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 LK06_RS15880 0dbae9ffeb7bf71024d9022d68e8c76d 421 Pfam PF02096 60Kd inner membrane protein 38 254 2.2E-58 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 LK06_RS15880 0dbae9ffeb7bf71024d9022d68e8c76d 421 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 38 254 7.0E-63 T 06-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 SUPERFAMILY SSF56235 37 589 1.45E-149 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 46 582 7.6E-119 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 Pfam PF01019 Gamma-glutamyltranspeptidase 60 587 5.6E-153 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 141 159 3.8E-65 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 298 317 3.8E-65 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 494 511 3.8E-65 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 469 484 3.8E-65 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 409 427 3.8E-65 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 159 178 3.8E-65 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 268 284 3.8E-65 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 433 451 3.8E-65 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS27815 a95032f9d530677ecf1a1640c649c676 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 67 92 3.8E-65 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 LK06_RS05430 3cd22e6a1431cd683940e5f12c16e260 530 Pfam PF03824 High-affinity nickel-transport protein 245 521 8.8E-12 T 06-07-2017 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 LK06_RS18130 a02bc081385c949fb7365aaf675d1d83 269 Gene3D G3DSA:3.20.20.370 43 238 9.1E-50 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS18130 a02bc081385c949fb7365aaf675d1d83 269 SUPERFAMILY SSF88713 40 238 8.9E-54 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS18130 a02bc081385c949fb7365aaf675d1d83 269 Pfam PF01522 Polysaccharide deacetylase 45 164 1.1E-28 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS21365 bf023213bbdb37387428017cc69691f8 180 SUPERFAMILY SSF69118 3 171 2.74E-48 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS21365 bf023213bbdb37387428017cc69691f8 180 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 180 85.396 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS21365 bf023213bbdb37387428017cc69691f8 180 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 112 160 7.4E-20 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS21365 bf023213bbdb37387428017cc69691f8 180 Gene3D G3DSA:1.20.1290.10 2 174 3.4E-56 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS21365 bf023213bbdb37387428017cc69691f8 180 Pfam PF02627 Carboxymuconolactone decarboxylase family 97 176 7.7E-14 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS21365 bf023213bbdb37387428017cc69691f8 180 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 176 1.4E-95 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS06105 526cda679ad022d4e1e51b792a31d929 265 Pfam PF06314 Acetoacetate decarboxylase (ADC) 23 222 4.7E-42 T 06-07-2017 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 LK06_RS06105 526cda679ad022d4e1e51b792a31d929 265 SUPERFAMILY SSF160104 28 224 1.83E-41 T 06-07-2017 LK06_RS06105 526cda679ad022d4e1e51b792a31d929 265 Gene3D G3DSA:2.40.400.10 30 252 3.3E-50 T 06-07-2017 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 LK06_RS06090 9ed322eba870e602dd6df8ecbb2792dc 412 Pfam PF04909 Amidohydrolase 46 368 9.0E-42 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS06090 9ed322eba870e602dd6df8ecbb2792dc 412 Gene3D G3DSA:3.20.20.140 8 369 1.7E-55 T 06-07-2017 LK06_RS06090 9ed322eba870e602dd6df8ecbb2792dc 412 SUPERFAMILY SSF51556 6 369 1.57E-62 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 PRINTS PR00149 Fumarate lyase superfamily signature 109 127 5.4E-20 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 5.4E-20 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 PRINTS PR00149 Fumarate lyase superfamily signature 154 172 5.4E-20 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 PRINTS PR00149 Fumarate lyase superfamily signature 296 312 5.4E-20 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 SMART SM00998 384 463 3.8E-9 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 Pfam PF00206 Lyase 29 319 3.6E-38 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 Gene3D G3DSA:1.20.200.10 112 388 2.2E-90 T 06-07-2017 LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 Pfam PF10397 Adenylosuccinate lyase C-terminus 385 462 5.0E-10 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 Gene3D G3DSA:1.10.275.10 20 111 1.6E-29 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 21 369 2.9E-111 T 06-07-2017 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 ProSitePatterns PS00163 Fumarate lyases signature. 296 305 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 Gene3D G3DSA:1.10.40.30 389 463 2.9E-16 T 06-07-2017 LK06_RS26365 92479db8c35132e5eb4cdd2e60a539ad 465 SUPERFAMILY SSF48557 28 463 4.71E-91 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 LK06_RS03340 c8b02731df84523eae01c8eff4f296f7 334 Pfam PF00892 EamA-like transporter family 159 304 1.0E-10 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS03340 c8b02731df84523eae01c8eff4f296f7 334 Pfam PF00892 EamA-like transporter family 18 147 1.3E-14 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS03340 c8b02731df84523eae01c8eff4f296f7 334 SUPERFAMILY SSF103481 52 148 6.93E-12 T 06-07-2017 LK06_RS03340 c8b02731df84523eae01c8eff4f296f7 334 SUPERFAMILY SSF103481 235 307 1.96E-9 T 06-07-2017 LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 502 5.6E-82 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 PRINTS PR01036 Tetracycline resistance protein TetB signature 412 431 4.3E-6 T 06-07-2017 LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 4.3E-6 T 06-07-2017 LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 4.3E-6 T 06-07-2017 LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 4.3E-6 T 06-07-2017 LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 Gene3D G3DSA:1.20.1250.20 276 437 2.1E-20 T 06-07-2017 LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 Gene3D G3DSA:1.20.1250.20 484 507 2.1E-20 T 06-07-2017 LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 Gene3D G3DSA:1.20.1250.20 26 202 3.1E-36 T 06-07-2017 LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 SUPERFAMILY SSF46785 557 647 2.15E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 Pfam PF07690 Major Facilitator Superfamily 29 421 6.4E-54 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 Gene3D G3DSA:1.10.10.10 551 658 2.3E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 SUPERFAMILY SSF103473 479 506 1.05E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 SUPERFAMILY SSF103473 260 431 1.05E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08645 929285346c3fdf174d0a218f1246432d 679 SUPERFAMILY SSF103473 26 213 1.05E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 Gene3D G3DSA:1.20.1110.10 87 148 3.4E-101 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 Gene3D G3DSA:1.20.1110.10 633 934 3.4E-101 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 Pfam PF12710 haloacid dehalogenase-like hydrolase 568 675 4.3E-6 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 Pfam PF00689 Cation transporting ATPase, C-terminus 750 930 2.4E-45 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 364 370 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 SUPERFAMILY SSF81653 153 261 1.57E-26 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 SUPERFAMILY SSF81660 368 571 4.58E-54 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 Gene3D G3DSA:3.40.1110.10 352 566 3.6E-59 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 Pfam PF00122 E1-E2 ATPase 122 353 1.1E-61 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 Pfam PF00690 Cation transporter/ATPase, N-terminus 37 101 6.8E-15 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 SMART SM00831 34 107 3.0E-17 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 Gene3D G3DSA:2.70.150.10 149 261 3.0E-37 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 Gene3D G3DSA:2.70.150.10 52 86 3.0E-37 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 362 376 2.2E-36 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 688 700 2.2E-36 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 201 215 2.2E-36 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 581 591 2.2E-36 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 664 683 2.2E-36 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 559 570 2.2E-36 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 SUPERFAMILY SSF81665 37 154 7.32E-113 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 SUPERFAMILY SSF81665 714 936 7.32E-113 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 SUPERFAMILY SSF81665 263 356 7.32E-113 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 267 384 6.6E-23 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 638 745 3.5E-31 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 282 304 2.6E-14 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 355 376 2.6E-14 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 486 504 2.6E-14 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 94 108 2.6E-14 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 Pfam PF13246 Cation transport ATPase (P-type) 414 501 7.0E-22 T 06-07-2017 LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 SUPERFAMILY SSF56784 516 770 3.96E-58 T 06-07-2017 IPR023214 HAD-like domain LK06_RS00280 4f7a95a1a5e00877c016c584f3c20a0e 945 SUPERFAMILY SSF56784 360 380 3.96E-58 T 06-07-2017 IPR023214 HAD-like domain LK06_RS04990 1dbf18eceda30cbe0c5cdff87fc227aa 334 SUPERFAMILY SSF54534 210 331 3.93E-25 T 06-07-2017 LK06_RS04990 1dbf18eceda30cbe0c5cdff87fc227aa 334 Gene3D G3DSA:3.10.50.40 58 183 1.9E-27 T 06-07-2017 LK06_RS04990 1dbf18eceda30cbe0c5cdff87fc227aa 334 SUPERFAMILY SSF54534 55 187 2.75E-27 T 06-07-2017 LK06_RS04990 1dbf18eceda30cbe0c5cdff87fc227aa 334 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 238 331 8.5E-17 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 LK06_RS04990 1dbf18eceda30cbe0c5cdff87fc227aa 334 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 90 181 7.2E-19 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 LK06_RS04990 1dbf18eceda30cbe0c5cdff87fc227aa 334 Gene3D G3DSA:3.10.50.40 220 331 4.4E-22 T 06-07-2017 LK06_RS16730 e5b7bd9c75ac44770d1caff22a951d51 197 SUPERFAMILY SSF48150 17 148 3.84E-13 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS16730 e5b7bd9c75ac44770d1caff22a951d51 197 Gene3D G3DSA:1.10.340.30 18 137 2.4E-10 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS16730 e5b7bd9c75ac44770d1caff22a951d51 197 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 191 1.0E-12 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LK06_RS16730 e5b7bd9c75ac44770d1caff22a951d51 197 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 4 193 1.8E-99 T 06-07-2017 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD LK06_RS05880 76ba6d610c1ab83e5ddb1a147a5a4968 179 SUPERFAMILY SSF49777 8 167 3.53E-50 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein LK06_RS05880 76ba6d610c1ab83e5ddb1a147a5a4968 179 Gene3D G3DSA:3.90.280.10 19 175 1.6E-53 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein LK06_RS05880 76ba6d610c1ab83e5ddb1a147a5a4968 179 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 40 170 2.1E-40 T 06-07-2017 IPR005247 YbhB/YbcL LK06_RS05880 76ba6d610c1ab83e5ddb1a147a5a4968 179 Pfam PF01161 Phosphatidylethanolamine-binding protein 40 173 1.3E-37 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein LK06_RS21480 da37851cdd57054b347b7cd1f452fd9d 124 Pfam PF02467 Transcription factor WhiB 30 98 1.2E-21 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS21480 da37851cdd57054b347b7cd1f452fd9d 124 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 9 106 18.464 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS19095 6af131dde44e2781fa8d2040e02c4120 223 Gene3D G3DSA:1.10.10.10 123 221 9.8E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19095 6af131dde44e2781fa8d2040e02c4120 223 SMART SM00862 144 219 1.3E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS19095 6af131dde44e2781fa8d2040e02c4120 223 Pfam PF00072 Response regulator receiver domain 4 112 4.9E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS19095 6af131dde44e2781fa8d2040e02c4120 223 SUPERFAMILY SSF46894 120 220 3.4E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS19095 6af131dde44e2781fa8d2040e02c4120 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 219 1.9E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS19095 6af131dde44e2781fa8d2040e02c4120 223 Gene3D G3DSA:3.40.50.2300 4 119 3.8E-34 T 06-07-2017 LK06_RS19095 6af131dde44e2781fa8d2040e02c4120 223 SUPERFAMILY SSF52172 1 118 9.11E-37 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS19095 6af131dde44e2781fa8d2040e02c4120 223 SMART SM00448 1 112 1.4E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS24105 a1d51ab1d4ea6fd3a91f7c2274b1e662 132 Pfam PF05331 Protein of unknown function (DUF742) 20 132 2.6E-39 T 06-07-2017 IPR007995 Protein of unknown function DUF742 LK06_RS04625 e65239bebb9deed2e3bb4704e13ac6d5 223 SMART SM00563 35 154 5.7E-33 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS04625 e65239bebb9deed2e3bb4704e13ac6d5 223 Pfam PF01553 Acyltransferase 21 151 1.4E-22 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS04625 e65239bebb9deed2e3bb4704e13ac6d5 223 Gene3D G3DSA:3.40.1130.10 8 207 2.9E-34 T 06-07-2017 LK06_RS04625 e65239bebb9deed2e3bb4704e13ac6d5 223 SUPERFAMILY SSF69593 6 221 1.57E-48 T 06-07-2017 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 Gene3D G3DSA:3.30.300.50 59 109 6.9E-10 T 06-07-2017 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 249 260 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 Pfam PF00089 Trypsin 115 290 3.3E-13 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 Gene3D G3DSA:2.40.10.10 199 286 4.2E-29 T 06-07-2017 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 PIRSF PIRSF001134 10 299 1.9E-95 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 Gene3D G3DSA:2.40.10.10 115 198 3.3E-30 T 06-07-2017 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 264 278 2.5E-45 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 199 219 2.5E-45 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 220 237 2.5E-45 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 240 263 2.5E-45 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 141 155 2.5E-45 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 143 148 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 SUPERFAMILY SSF50494 121 293 7.7E-39 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS05570 401fcc7b460523bc5101a69f0935f2b2 299 Pfam PF02983 Alpha-lytic protease prodomain 44 98 5.5E-13 T 06-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 LK06_RS31000 8d724e86ec24646c3564d6840ab82564 104 SMART SM01012 15 70 4.6E-16 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 LK06_RS31000 8d724e86ec24646c3564d6840ab82564 104 SUPERFAMILY SSF52172 8 70 4.97E-7 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS31000 8d724e86ec24646c3564d6840ab82564 104 Pfam PF03861 ANTAR domain 17 70 3.7E-15 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 LK06_RS31000 8d724e86ec24646c3564d6840ab82564 104 PIRSF PIRSF010636 3 104 6.3E-44 T 06-07-2017 IPR024189 ANTAR transcription anti-termination regulator LK06_RS31000 8d724e86ec24646c3564d6840ab82564 104 Gene3D G3DSA:1.10.10.10 18 70 1.4E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31210 0b32dbf4e0999df38687e3e2835e3e22 237 SUPERFAMILY SSF53448 1 228 2.25E-59 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS31210 0b32dbf4e0999df38687e3e2835e3e22 237 Gene3D G3DSA:3.90.550.10 1 230 2.9E-57 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS31210 0b32dbf4e0999df38687e3e2835e3e22 237 Pfam PF00483 Nucleotidyl transferase 3 226 2.1E-35 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LK06_RS30020 4f49d8bf60d46c4ef48adb418604b727 293 Gene3D G3DSA:3.40.50.10490 33 147 1.3E-15 T 06-07-2017 LK06_RS30020 4f49d8bf60d46c4ef48adb418604b727 293 Pfam PF01380 SIS domain 34 132 5.0E-6 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 LK06_RS30020 4f49d8bf60d46c4ef48adb418604b727 293 SUPERFAMILY SSF53697 4 289 5.07E-42 T 06-07-2017 LK06_RS30020 4f49d8bf60d46c4ef48adb418604b727 293 Gene3D G3DSA:3.40.50.10490 253 289 1.5E-7 T 06-07-2017 LK06_RS30020 4f49d8bf60d46c4ef48adb418604b727 293 Gene3D G3DSA:3.40.50.10490 174 248 2.5E-20 T 06-07-2017 LK06_RS10660 1066b82a980a1f1e1ffece6623a1134b 347 Gene3D G3DSA:2.130.10.10 66 238 8.1E-7 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS10660 1066b82a980a1f1e1ffece6623a1134b 347 SUPERFAMILY SSF63829 59 252 2.29E-8 T 06-07-2017 LK06_RS10660 1066b82a980a1f1e1ffece6623a1134b 347 Pfam PF13449 Esterase-like activity of phytase 64 331 4.9E-66 T 06-07-2017 IPR027372 Phytase-like domain LK06_RS27475 3ac9806dca50fc5aa99f18f13c23997a 227 Gene3D G3DSA:3.40.50.720 1 211 1.2E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27475 3ac9806dca50fc5aa99f18f13c23997a 227 Pfam PF13460 NAD(P)H-binding 3 200 8.5E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27475 3ac9806dca50fc5aa99f18f13c23997a 227 SUPERFAMILY SSF51735 1 211 1.1E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26325 2ed4fa3518d957b109febe44bffd2cc4 372 Gene3D G3DSA:3.50.50.60 3 85 9.9E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26325 2ed4fa3518d957b109febe44bffd2cc4 372 Gene3D G3DSA:3.50.50.60 144 219 9.9E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26325 2ed4fa3518d957b109febe44bffd2cc4 372 Gene3D G3DSA:3.50.50.60 308 364 9.9E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26325 2ed4fa3518d957b109febe44bffd2cc4 372 SUPERFAMILY SSF51905 10 220 1.08E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26325 2ed4fa3518d957b109febe44bffd2cc4 372 SUPERFAMILY SSF51905 308 364 1.08E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26325 2ed4fa3518d957b109febe44bffd2cc4 372 Gene3D G3DSA:3.30.9.10 91 143 4.1E-12 T 06-07-2017 LK06_RS26325 2ed4fa3518d957b109febe44bffd2cc4 372 Gene3D G3DSA:3.30.9.10 220 307 4.1E-12 T 06-07-2017 LK06_RS26325 2ed4fa3518d957b109febe44bffd2cc4 372 Pfam PF01266 FAD dependent oxidoreductase 10 347 1.6E-50 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS30315 7e07020ba0b84e16601b053cc98e28cd 332 SUPERFAMILY SSF63829 262 313 5.4E-43 T 06-07-2017 LK06_RS30315 7e07020ba0b84e16601b053cc98e28cd 332 SUPERFAMILY SSF63829 9 230 5.4E-43 T 06-07-2017 LK06_RS30315 7e07020ba0b84e16601b053cc98e28cd 332 Gene3D G3DSA:2.120.10.30 5 313 1.7E-51 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like LK06_RS30315 7e07020ba0b84e16601b053cc98e28cd 332 Pfam PF03088 Strictosidine synthase 117 195 2.5E-17 T 06-07-2017 IPR018119 Strictosidine synthase, conserved region GO:0009058|GO:0016844 LK06_RS21900 eeae54d1638511ec96f604aacfe79f43 327 Pfam PF00005 ABC transporter 23 181 1.4E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS21900 eeae54d1638511ec96f604aacfe79f43 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 1.8E-20 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21900 eeae54d1638511ec96f604aacfe79f43 327 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS21900 eeae54d1638511ec96f604aacfe79f43 327 SMART SM00382 31 231 2.8E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS21900 eeae54d1638511ec96f604aacfe79f43 327 SUPERFAMILY SSF52540 2 252 6.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21900 eeae54d1638511ec96f604aacfe79f43 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 317 1.6E-28 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21900 eeae54d1638511ec96f604aacfe79f43 327 Gene3D G3DSA:3.40.50.300 2 255 1.4E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 Gene3D G3DSA:3.40.50.720 1 203 1.0E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 405 1.9E-116 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 SUPERFAMILY SSF52413 311 428 3.79E-20 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 SUPERFAMILY SSF51735 1 199 3.6E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 SMART SM00984 320 427 1.8E-18 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 Gene3D G3DSA:3.40.50.720 238 427 4.7E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 406 4.7E-11 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 Gene3D G3DSA:1.20.5.100 207 235 9.9E-11 T 06-07-2017 LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 208 301 1.8E-27 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 SUPERFAMILY SSF48179 207 301 1.98E-25 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 PIRSF PIRSF000124 1 441 1.1E-132 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 190 2.9E-54 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LK06_RS25925 94b52e1c9b4441a37be7c2b375d1f520 441 PIRSF PIRSF500135 1 441 1.5E-212 T 06-07-2017 IPR028358 GDP-mannose 6-dehydrogenase GO:0042121|GO:0047919 KEGG: 00040+1.1.1.13|KEGG: 00051+1.1.1.132|KEGG: 00520+1.1.1.132|MetaCyc: PWY-6073|MetaCyc: PWY-6082 LK06_RS23810 18114a16f998309aa5193c0da6da3cf0 200 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 15 194 1.9E-49 T 06-07-2017 IPR017520 Conserved hypothetical protein CHP03086 LK06_RS23810 18114a16f998309aa5193c0da6da3cf0 200 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 15 194 4.0E-23 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type LK06_RS23810 18114a16f998309aa5193c0da6da3cf0 200 SUPERFAMILY SSF109854 1 140 4.88E-20 T 06-07-2017 LK06_RS23810 18114a16f998309aa5193c0da6da3cf0 200 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 16 134 3.0E-10 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 LK06_RS01595 6dbe7b4976e487eef3dfe7ededfc7b9c 235 Gene3D G3DSA:1.20.950.10 27 225 7.1E-12 T 06-07-2017 LK06_RS01595 6dbe7b4976e487eef3dfe7ededfc7b9c 235 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 20 234 7.2E-79 T 06-07-2017 IPR011138 Succinate dehydrogenase cytochrome b558 subunit LK06_RS01595 6dbe7b4976e487eef3dfe7ededfc7b9c 235 SUPERFAMILY SSF81343 6 234 3.66E-51 T 06-07-2017 LK06_RS21200 70215cb70005402f21880c2d808c212d 568 Pfam PF07969 Amidohydrolase family 51 517 1.3E-60 T 06-07-2017 IPR013108 Amidohydrolase 3 LK06_RS21200 70215cb70005402f21880c2d808c212d 568 SUPERFAMILY SSF51556 62 299 1.87E-78 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS21200 70215cb70005402f21880c2d808c212d 568 SUPERFAMILY SSF51556 344 472 1.87E-78 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS21200 70215cb70005402f21880c2d808c212d 568 Gene3D G3DSA:2.30.40.10 4 75 2.6E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS21200 70215cb70005402f21880c2d808c212d 568 Gene3D G3DSA:3.20.20.140 76 291 4.8E-116 T 06-07-2017 LK06_RS21200 70215cb70005402f21880c2d808c212d 568 Gene3D G3DSA:3.20.20.140 396 456 4.8E-116 T 06-07-2017 LK06_RS21200 70215cb70005402f21880c2d808c212d 568 Gene3D G3DSA:2.30.40.10 457 522 1.1E-9 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS21200 70215cb70005402f21880c2d808c212d 568 SUPERFAMILY SSF51338 472 523 3.77E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS21200 70215cb70005402f21880c2d808c212d 568 SUPERFAMILY SSF51338 3 62 3.77E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS05055 f31cd500ffee3f7861a3bc83ce8b9b15 300 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 80 243 2.8E-22 T 06-07-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 LK06_RS05055 f31cd500ffee3f7861a3bc83ce8b9b15 300 Gene3D G3DSA:3.10.330.20 2 75 8.4E-33 T 06-07-2017 LK06_RS05055 f31cd500ffee3f7861a3bc83ce8b9b15 300 Gene3D G3DSA:3.40.50.150 77 283 6.9E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS05055 f31cd500ffee3f7861a3bc83ce8b9b15 300 PIRSF PIRSF017269 7 277 3.3E-86 T 06-07-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 LK06_RS05055 f31cd500ffee3f7861a3bc83ce8b9b15 300 SUPERFAMILY SSF53335 13 266 2.31E-71 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS05055 f31cd500ffee3f7861a3bc83ce8b9b15 300 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 11 61 2.9E-28 T 06-07-2017 LK06_RS18355 bf3a4fcd0022bf09f6fa617d8b5643bd 301 SUPERFAMILY SSF53697 109 276 1.44E-37 T 06-07-2017 LK06_RS18355 bf3a4fcd0022bf09f6fa617d8b5643bd 301 Pfam PF01418 Helix-turn-helix domain, rpiR family 16 89 5.9E-13 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 LK06_RS18355 bf3a4fcd0022bf09f6fa617d8b5643bd 301 Pfam PF01380 SIS domain 142 271 8.3E-22 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 LK06_RS18355 bf3a4fcd0022bf09f6fa617d8b5643bd 301 SUPERFAMILY SSF46689 15 88 4.48E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS18355 bf3a4fcd0022bf09f6fa617d8b5643bd 301 Gene3D G3DSA:3.40.50.10490 112 280 4.0E-39 T 06-07-2017 LK06_RS18355 bf3a4fcd0022bf09f6fa617d8b5643bd 301 Gene3D G3DSA:1.10.10.10 15 90 3.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23310 fc8b8cb42d7d72c91eabe1a7fafbf688 124 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 120 18.645 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23310 fc8b8cb42d7d72c91eabe1a7fafbf688 124 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 18 78 3.0E-27 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23310 fc8b8cb42d7d72c91eabe1a7fafbf688 124 SUPERFAMILY SSF51344 5 86 6.54E-22 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23310 fc8b8cb42d7d72c91eabe1a7fafbf688 124 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 3.1E-24 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23310 fc8b8cb42d7d72c91eabe1a7fafbf688 124 Gene3D G3DSA:2.60.15.10 4 91 1.1E-25 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS23310 fc8b8cb42d7d72c91eabe1a7fafbf688 124 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 115 2.0E-26 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 LK06_RS29940 0732fbe5088722ce48a91f4495d8b3a8 108 SUPERFAMILY SSF52833 21 104 1.29E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS29940 0732fbe5088722ce48a91f4495d8b3a8 108 Gene3D G3DSA:3.40.30.10 22 106 3.1E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS29940 0732fbe5088722ce48a91f4495d8b3a8 108 Pfam PF00085 Thioredoxin 22 101 3.0E-9 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 LK06_RS07905 ad7912c49ca988199c0863117a960a2b 414 SMART SM00825 Beta-ketoacyl synthase 9 413 3.8E-5 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS07905 ad7912c49ca988199c0863117a960a2b 414 Gene3D G3DSA:3.40.47.10 273 410 1.5E-31 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07905 ad7912c49ca988199c0863117a960a2b 414 Gene3D G3DSA:3.40.47.10 5 263 2.0E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07905 ad7912c49ca988199c0863117a960a2b 414 SUPERFAMILY SSF53901 5 255 1.15E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07905 ad7912c49ca988199c0863117a960a2b 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 368 7.7E-23 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS07905 ad7912c49ca988199c0863117a960a2b 414 SUPERFAMILY SSF53901 218 410 5.77E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS07905 ad7912c49ca988199c0863117a960a2b 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 249 1.2E-32 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS10520 9e3d2898ce3ec5e7ea80322c750cfc7f 435 Gene3D G3DSA:1.10.150.130 78 201 2.0E-17 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS10520 9e3d2898ce3ec5e7ea80322c750cfc7f 435 Pfam PF00589 Phage integrase family 212 395 1.5E-30 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS10520 9e3d2898ce3ec5e7ea80322c750cfc7f 435 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 78 135 2.4E-9 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS10520 9e3d2898ce3ec5e7ea80322c750cfc7f 435 SUPERFAMILY SSF56349 164 404 2.77E-68 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS10520 9e3d2898ce3ec5e7ea80322c750cfc7f 435 SUPERFAMILY SSF56349 78 136 2.77E-68 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS10520 9e3d2898ce3ec5e7ea80322c750cfc7f 435 Gene3D G3DSA:1.10.443.10 211 404 1.0E-45 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 PRINTS PR00046 Major sigma-70 factor signature 60 73 4.2E-5 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 PRINTS PR00046 Major sigma-70 factor signature 146 158 4.2E-5 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 PRINTS PR00046 Major sigma-70 factor signature 163 178 4.2E-5 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 PRINTS PR00046 Major sigma-70 factor signature 178 189 4.2E-5 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 Pfam PF04542 Sigma-70 region 2 31 102 1.3E-10 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 Gene3D G3DSA:1.10.10.10 136 193 9.8E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 SUPERFAMILY SSF88659 120 193 9.35E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 190 4.1E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 SUPERFAMILY SSF88946 15 116 5.69E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 Gene3D G3DSA:1.10.1740.10 15 129 2.3E-16 T 06-07-2017 LK06_RS20155 8ae61dac5e472db5560ffc341aba1f4d 195 Pfam PF04545 Sigma-70, region 4 142 191 7.7E-12 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31740 c788f8a72fd4d8e0a815c2cc28988601 247 Pfam PF13489 Methyltransferase domain 89 201 1.9E-9 T 06-07-2017 LK06_RS31740 c788f8a72fd4d8e0a815c2cc28988601 247 SUPERFAMILY SSF53335 173 209 4.02E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS31740 c788f8a72fd4d8e0a815c2cc28988601 247 SUPERFAMILY SSF53335 75 136 4.02E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS31740 c788f8a72fd4d8e0a815c2cc28988601 247 Gene3D G3DSA:3.40.50.150 76 214 8.3E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS23625 e8f9dccc31309d4b63aabd1873853062 467 Gene3D G3DSA:3.90.1200.10 258 411 2.5E-4 T 06-07-2017 LK06_RS23625 e8f9dccc31309d4b63aabd1873853062 467 SUPERFAMILY SSF56112 161 428 4.42E-20 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 9.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 9.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 9.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 9.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 9.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 9.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.9E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.9E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.9E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 Pfam PF00106 short chain dehydrogenase 1 187 1.1E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 Gene3D G3DSA:3.40.50.720 1 242 6.1E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29755 21e3093ecc80fed6a302c21f55ffe23a 254 SUPERFAMILY SSF51735 1 239 2.58E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01635 8c01b209e97264c185d1ab10c20ec203 282 SUPERFAMILY SSF88713 86 274 8.53E-61 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS01635 8c01b209e97264c185d1ab10c20ec203 282 Gene3D G3DSA:3.20.20.370 79 274 4.0E-62 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS01635 8c01b209e97264c185d1ab10c20ec203 282 Pfam PF01522 Polysaccharide deacetylase 93 211 2.1E-35 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS14420 87f3e65b48ac2140165ae577818c4767 195 ProSitePatterns PS00380 Rhodanese signature 1. 33 44 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 LK06_RS14420 87f3e65b48ac2140165ae577818c4767 195 Gene3D G3DSA:3.40.250.10 13 109 1.1E-24 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14420 87f3e65b48ac2140165ae577818c4767 195 SMART SM00450 8 105 4.5E-18 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14420 87f3e65b48ac2140165ae577818c4767 195 Pfam PF00581 Rhodanese-like domain 13 101 1.8E-9 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14420 87f3e65b48ac2140165ae577818c4767 195 SUPERFAMILY SSF52821 12 108 1.44E-25 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS14420 87f3e65b48ac2140165ae577818c4767 195 Pfam PF11127 Protein of unknown function (DUF2892) 119 177 1.2E-10 T 06-07-2017 IPR021309 Protein of unknown function DUF2892 LK06_RS23890 5c8cd9c3673e0e3c67ed25e2320f769d 499 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 17 484 3.2E-186 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS23890 5c8cd9c3673e0e3c67ed25e2320f769d 499 SUPERFAMILY SSF75304 3 483 5.49E-159 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS23890 5c8cd9c3673e0e3c67ed25e2320f769d 499 Pfam PF01425 Amidase 27 473 8.5E-157 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS23890 5c8cd9c3673e0e3c67ed25e2320f769d 499 Gene3D G3DSA:3.90.1300.10 3 486 3.3E-174 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS23890 5c8cd9c3673e0e3c67ed25e2320f769d 499 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 14 485 90.347 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS23890 5c8cd9c3673e0e3c67ed25e2320f769d 499 ProSitePatterns PS00571 Amidases signature. 155 186 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Gene3D G3DSA:3.40.47.10 309 471 5.4E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Gene3D G3DSA:3.40.50.720 1229 1445 2.5E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Gene3D G3DSA:1.10.1200.10 951 1022 2.5E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SMART SM00826 1475 1630 1.4E-4 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SUPERFAMILY SSF52151 762 862 4.19E-47 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SUPERFAMILY SSF52151 587 699 4.19E-47 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SUPERFAMILY SSF55048 699 760 3.27E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SUPERFAMILY SSF53901 7 129 9.56E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SUPERFAMILY SSF53901 193 417 9.56E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 296 1.3E-55 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Gene3D G3DSA:3.30.70.250 697 753 2.7E-9 T 06-07-2017 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Gene3D G3DSA:3.40.366.10 583 693 1.2E-42 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Gene3D G3DSA:3.40.366.10 760 861 1.2E-42 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 430 542 7.8E-8 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Gene3D G3DSA:3.40.47.10 12 133 3.8E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Gene3D G3DSA:3.40.47.10 166 308 3.8E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Pfam PF08659 KR domain 1230 1409 1.1E-27 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1228 1411 1.6E-11 T 06-07-2017 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Gene3D G3DSA:3.10.129.10 1476 1538 7.1E-4 T 06-07-2017 IPR029069 HotDog domain LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SUPERFAMILY SSF47336 950 1036 1.57E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Pfam PF14765 Polyketide synthase dehydratase 1484 1755 6.7E-46 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SMART SM00825 Beta-ketoacyl synthase 12 472 1.5E-58 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 304 418 2.6E-30 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 591 887 8.7E-40 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Pfam PF00550 Phosphopantetheine attachment site 952 1019 5.0E-7 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 Pfam PF00698 Acyl transferase domain 626 840 9.9E-28 T 06-07-2017 IPR014043 Acyl transferase LK06_RS02495 c907ad35ea5620be6752eb60401d4a3c 1963 SUPERFAMILY SSF51735 1227 1457 2.02E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS14620 fa5e92a693bcbcf93fdba302ad51658d 262 Pfam PF01263 Aldose 1-epimerase 6 180 8.9E-18 T 06-07-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 LK06_RS14620 fa5e92a693bcbcf93fdba302ad51658d 262 Gene3D G3DSA:2.70.98.10 34 238 2.3E-12 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 LK06_RS14620 fa5e92a693bcbcf93fdba302ad51658d 262 SUPERFAMILY SSF74650 6 252 1.19E-39 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 LK06_RS05555 12f16d232fc2c166f7c9b2f7ab499c8d 322 Pfam PF11799 impB/mucB/samB family C-terminal domain 173 278 3.5E-10 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS05555 12f16d232fc2c166f7c9b2f7ab499c8d 322 Gene3D G3DSA:3.30.70.270 17 89 2.4E-9 T 06-07-2017 LK06_RS05555 12f16d232fc2c166f7c9b2f7ab499c8d 322 Pfam PF00817 impB/mucB/samB family 17 87 2.1E-8 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS05555 12f16d232fc2c166f7c9b2f7ab499c8d 322 Gene3D G3DSA:1.10.150.20 102 175 6.4E-18 T 06-07-2017 LK06_RS05555 12f16d232fc2c166f7c9b2f7ab499c8d 322 SUPERFAMILY SSF100879 176 267 2.55E-11 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS05555 12f16d232fc2c166f7c9b2f7ab499c8d 322 Gene3D G3DSA:3.30.1490.100 178 281 6.6E-9 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS05555 12f16d232fc2c166f7c9b2f7ab499c8d 322 SUPERFAMILY SSF56672 13 170 2.05E-31 T 06-07-2017 LK06_RS18700 dbfb8dbea995ebac1427cb05c98a9d01 141 Gene3D G3DSA:3.40.630.30 14 120 1.5E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS18700 dbfb8dbea995ebac1427cb05c98a9d01 141 Pfam PF00583 Acetyltransferase (GNAT) family 36 112 2.8E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS18700 dbfb8dbea995ebac1427cb05c98a9d01 141 SUPERFAMILY SSF55729 17 129 5.06E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS15315 e205e184d02fa1558217b4f74c8ca264 325 PIRSF PIRSF006232 22 318 4.2E-92 T 06-07-2017 IPR012093 Pirin LK06_RS15315 e205e184d02fa1558217b4f74c8ca264 325 Pfam PF05726 Pirin C-terminal cupin domain 201 309 6.6E-33 T 06-07-2017 IPR008778 Pirin, C-terminal domain LK06_RS15315 e205e184d02fa1558217b4f74c8ca264 325 Gene3D G3DSA:2.60.120.10 24 282 4.0E-76 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS15315 e205e184d02fa1558217b4f74c8ca264 325 SUPERFAMILY SSF51182 24 316 2.05E-82 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS15315 e205e184d02fa1558217b4f74c8ca264 325 Pfam PF02678 Pirin 42 146 1.1E-31 T 06-07-2017 IPR003829 Pirin, N-terminal domain LK06_RS02615 ec57fd4979ef91d23e9835d047623253 393 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 371 1.5E-23 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain LK06_RS02615 ec57fd4979ef91d23e9835d047623253 393 Gene3D G3DSA:2.40.110.10 116 202 1.1E-23 T 06-07-2017 LK06_RS02615 ec57fd4979ef91d23e9835d047623253 393 Gene3D G3DSA:1.10.540.10 7 111 3.5E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS02615 ec57fd4979ef91d23e9835d047623253 393 PIRSF PIRSF016578 2 393 2.3E-123 T 06-07-2017 LK06_RS02615 ec57fd4979ef91d23e9835d047623253 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 88 1.1E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS02615 ec57fd4979ef91d23e9835d047623253 393 SUPERFAMILY SSF56645 10 208 1.31E-33 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS02615 ec57fd4979ef91d23e9835d047623253 393 SUPERFAMILY SSF47203 232 381 7.99E-9 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS02615 ec57fd4979ef91d23e9835d047623253 393 Gene3D G3DSA:1.20.140.10 203 392 3.0E-41 T 06-07-2017 LK06_RS30500 5c39ac496a577f0f76223bd694436660 392 Gene3D G3DSA:1.10.540.10 5 120 5.0E-29 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS30500 5c39ac496a577f0f76223bd694436660 392 Gene3D G3DSA:2.40.110.10 122 216 1.9E-34 T 06-07-2017 LK06_RS30500 5c39ac496a577f0f76223bd694436660 392 Gene3D G3DSA:1.20.140.10 217 389 9.5E-36 T 06-07-2017 LK06_RS30500 5c39ac496a577f0f76223bd694436660 392 SUPERFAMILY SSF47203 228 388 2.26E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS30500 5c39ac496a577f0f76223bd694436660 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 381 3.6E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS30500 5c39ac496a577f0f76223bd694436660 392 SUPERFAMILY SSF56645 4 241 2.09E-71 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS30500 5c39ac496a577f0f76223bd694436660 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 206 3.7E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS30500 5c39ac496a577f0f76223bd694436660 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 4.0E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS03555 5c518e3b5f479a43765c0dfbd1146633 270 Pfam PF02567 Phenazine biosynthesis-like protein 6 266 6.4E-57 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LK06_RS03555 5c518e3b5f479a43765c0dfbd1146633 270 Gene3D G3DSA:3.10.310.10 127 258 2.1E-37 T 06-07-2017 LK06_RS03555 5c518e3b5f479a43765c0dfbd1146633 270 PIRSF PIRSF016184 1 270 9.6E-43 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LK06_RS03555 5c518e3b5f479a43765c0dfbd1146633 270 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 227 1.5E-32 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LK06_RS03555 5c518e3b5f479a43765c0dfbd1146633 270 Gene3D G3DSA:3.10.310.10 1 126 4.9E-40 T 06-07-2017 LK06_RS03555 5c518e3b5f479a43765c0dfbd1146633 270 SUPERFAMILY SSF54506 2 268 4.62E-70 T 06-07-2017 LK06_RS18260 448a9463521e87233492462680f9a39b 78 Pfam PF11662 Protein of unknown function (DUF3263) 6 78 1.2E-30 T 06-07-2017 IPR021678 Protein of unknown function DUF3263 LK06_RS06840 22b6b25be2e6d970a8ff205cbedec750 209 Gene3D G3DSA:3.40.50.300 1 197 1.3E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06840 22b6b25be2e6d970a8ff205cbedec750 209 SUPERFAMILY SSF52540 1 191 8.41E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06840 22b6b25be2e6d970a8ff205cbedec750 209 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 186 8.4E-50 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 LK06_RS06840 22b6b25be2e6d970a8ff205cbedec750 209 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 27.144 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 LK06_RS06840 22b6b25be2e6d970a8ff205cbedec750 209 Pfam PF01121 Dephospho-CoA kinase 4 177 3.6E-57 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 LK06_RS30695 2314d6b89448f85283a2d1ae11f54af4 487 SUPERFAMILY SSF52317 90 312 1.65E-17 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS04815 4bb01229dc40d77e1bc44cf6912dff7c 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.0E-16 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 LK06_RS04815 4bb01229dc40d77e1bc44cf6912dff7c 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.0E-16 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 LK06_RS04815 4bb01229dc40d77e1bc44cf6912dff7c 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.0E-16 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 LK06_RS04815 4bb01229dc40d77e1bc44cf6912dff7c 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 06-07-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS04815 4bb01229dc40d77e1bc44cf6912dff7c 64 Pfam PF01632 Ribosomal protein L35 2 62 1.5E-23 T 06-07-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS04815 4bb01229dc40d77e1bc44cf6912dff7c 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.567 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 LK06_RS04815 4bb01229dc40d77e1bc44cf6912dff7c 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 4.8E-25 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 LK06_RS04815 4bb01229dc40d77e1bc44cf6912dff7c 64 SUPERFAMILY SSF143034 2 63 1.31E-20 T 06-07-2017 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 SUPERFAMILY SSF54849 136 202 1.58E-24 T 06-07-2017 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 Gene3D G3DSA:1.10.560.10 366 518 1.3E-39 T 06-07-2017 IPR027413 GroEL-like equatorial domain LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 41.236 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 525 9.4E-93 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 Gene3D G3DSA:3.50.7.10 187 365 1.3E-96 T 06-07-2017 IPR027409 GroEL-like apical domain LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 SUPERFAMILY SSF52029 184 376 1.59E-80 T 06-07-2017 IPR027409 GroEL-like apical domain LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 SUPERFAMILY SSF48592 6 133 1.25E-72 T 06-07-2017 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 SUPERFAMILY SSF48592 406 521 1.25E-72 T 06-07-2017 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 PRINTS PR00298 60kDa chaperonin signature 268 291 5.2E-72 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 PRINTS PR00298 60kDa chaperonin signature 26 52 5.2E-72 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 PRINTS PR00298 60kDa chaperonin signature 350 375 5.2E-72 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 PRINTS PR00298 60kDa chaperonin signature 82 109 5.2E-72 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 PRINTS PR00298 60kDa chaperonin signature 398 419 5.2E-72 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 Gene3D G3DSA:1.10.560.10 6 186 8.2E-44 T 06-07-2017 IPR027413 GroEL-like equatorial domain LK06_RS20120 125431079c789c8cca8edc8cefd5e218 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 527 7.7E-246 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 LK06_RS03000 d3ae45a0481fcf1cfb746b81e8c67485 190 Pfam PF01381 Helix-turn-helix 15 67 8.6E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS03000 d3ae45a0481fcf1cfb746b81e8c67485 190 Gene3D G3DSA:1.10.260.40 11 110 6.7E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS03000 d3ae45a0481fcf1cfb746b81e8c67485 190 Pfam PF07883 Cupin domain 115 182 7.5E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel LK06_RS03000 d3ae45a0481fcf1cfb746b81e8c67485 190 SMART SM00530 14 69 5.6E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS03000 d3ae45a0481fcf1cfb746b81e8c67485 190 SUPERFAMILY SSF47413 7 75 1.88E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS03000 d3ae45a0481fcf1cfb746b81e8c67485 190 SUPERFAMILY SSF51182 62 184 1.62E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS03000 d3ae45a0481fcf1cfb746b81e8c67485 190 Gene3D G3DSA:2.60.120.10 111 188 1.1E-22 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS32200 9dab6ca84de2c443639f03a7c86a1f48 2141 Gene3D G3DSA:2.170.16.10 1983 2140 3.4E-17 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain LK06_RS32200 9dab6ca84de2c443639f03a7c86a1f48 2141 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1714 1793 1.2E-18 T 06-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 LK06_RS32200 9dab6ca84de2c443639f03a7c86a1f48 2141 SMART SM00306 1986 2097 0.0017 T 06-07-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 LK06_RS32200 9dab6ca84de2c443639f03a7c86a1f48 2141 Pfam PF05593 RHS Repeat 1207 1244 1.0E-4 T 06-07-2017 IPR031325 RHS repeat LK06_RS32200 9dab6ca84de2c443639f03a7c86a1f48 2141 Pfam PF05593 RHS Repeat 1249 1284 9.8E-5 T 06-07-2017 IPR031325 RHS repeat LK06_RS32200 9dab6ca84de2c443639f03a7c86a1f48 2141 Pfam PF07591 Pretoxin HINT domain 1996 2139 2.6E-12 T 06-07-2017 LK06_RS32200 9dab6ca84de2c443639f03a7c86a1f48 2141 SUPERFAMILY SSF51294 1988 2140 3.92E-14 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain LK06_RS32200 9dab6ca84de2c443639f03a7c86a1f48 2141 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1249 1285 3.0E-7 T 06-07-2017 IPR006530 YD repeat LK06_RS32200 9dab6ca84de2c443639f03a7c86a1f48 2141 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1207 1244 1.6E-4 T 06-07-2017 IPR006530 YD repeat LK06_RS20400 448c2e7fe6f7f1f8713263de6f9fb1ed 468 Pfam PF07690 Major Facilitator Superfamily 15 404 8.4E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS20400 448c2e7fe6f7f1f8713263de6f9fb1ed 468 Gene3D G3DSA:1.20.1250.20 6 194 4.3E-24 T 06-07-2017 LK06_RS20400 448c2e7fe6f7f1f8713263de6f9fb1ed 468 Gene3D G3DSA:1.20.1250.20 263 441 4.5E-11 T 06-07-2017 LK06_RS20400 448c2e7fe6f7f1f8713263de6f9fb1ed 468 SUPERFAMILY SSF103473 245 441 1.03E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS20400 448c2e7fe6f7f1f8713263de6f9fb1ed 468 SUPERFAMILY SSF103473 5 197 1.03E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS12920 ba922ef0a76fb9171e28b3132077aeb8 455 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 17 354 24.149 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12920 ba922ef0a76fb9171e28b3132077aeb8 455 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 230 243 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12920 ba922ef0a76fb9171e28b3132077aeb8 455 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 63 78 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12920 ba922ef0a76fb9171e28b3132077aeb8 455 Pfam PF00146 NADH dehydrogenase 24 347 6.9E-123 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS31520 77e82090f36ac2a7811f7d8725f6d06b 387 Gene3D G3DSA:3.90.180.10 8 188 5.1E-33 T 06-07-2017 IPR011032 GroES-like LK06_RS31520 77e82090f36ac2a7811f7d8725f6d06b 387 SUPERFAMILY SSF51735 158 357 5.78E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31520 77e82090f36ac2a7811f7d8725f6d06b 387 SMART SM00829 13 381 2.3E-9 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS31520 77e82090f36ac2a7811f7d8725f6d06b 387 Gene3D G3DSA:3.40.50.720 189 330 4.6E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31520 77e82090f36ac2a7811f7d8725f6d06b 387 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 183 204 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 LK06_RS31520 77e82090f36ac2a7811f7d8725f6d06b 387 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 147 5.6E-9 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS31520 77e82090f36ac2a7811f7d8725f6d06b 387 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 1 387 9.4E-175 T 06-07-2017 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 LK06_RS31520 77e82090f36ac2a7811f7d8725f6d06b 387 Pfam PF00107 Zinc-binding dehydrogenase 194 344 7.3E-32 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS31520 77e82090f36ac2a7811f7d8725f6d06b 387 SUPERFAMILY SSF50129 10 176 8.83E-28 T 06-07-2017 IPR011032 GroES-like LK06_RS10275 0e8fa69bb937a67e312e13ca459dc303 418 Pfam PF13439 Glycosyltransferase Family 4 13 187 6.7E-8 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS10275 0e8fa69bb937a67e312e13ca459dc303 418 SUPERFAMILY SSF53756 2 375 1.49E-67 T 06-07-2017 LK06_RS10275 0e8fa69bb937a67e312e13ca459dc303 418 Gene3D G3DSA:3.40.50.2000 196 354 1.8E-26 T 06-07-2017 LK06_RS10275 0e8fa69bb937a67e312e13ca459dc303 418 Pfam PF00534 Glycosyl transferases group 1 198 354 1.1E-36 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS17460 4b260c865ec516a5145430dfd3a8e6f1 232 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 192 6.3E-29 T 06-07-2017 LK06_RS17460 4b260c865ec516a5145430dfd3a8e6f1 232 Gene3D G3DSA:3.40.50.1000 6 106 5.5E-5 T 06-07-2017 IPR023214 HAD-like domain LK06_RS17460 4b260c865ec516a5145430dfd3a8e6f1 232 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 8 193 1.4E-17 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 LK06_RS17460 4b260c865ec516a5145430dfd3a8e6f1 232 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 8 205 6.6E-37 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial LK06_RS17460 4b260c865ec516a5145430dfd3a8e6f1 232 SUPERFAMILY SSF56784 5 208 6.36E-23 T 06-07-2017 IPR023214 HAD-like domain LK06_RS17460 4b260c865ec516a5145430dfd3a8e6f1 232 Gene3D G3DSA:3.40.50.1000 107 220 2.0E-32 T 06-07-2017 IPR023214 HAD-like domain LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 256 3.1E-70 T 06-07-2017 LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 SUPERFAMILY SSF51735 15 255 5.72E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.7E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.7E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.7E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.7E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.7E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.7E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS04860 1e1ce41866654c7f56f328e34f1e5f18 263 Gene3D G3DSA:3.40.50.720 11 256 1.0E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00200 9ccad99b4ab41f3152eb62ee42c20b10 294 Gene3D G3DSA:3.20.20.70 74 283 3.0E-25 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS00200 9ccad99b4ab41f3152eb62ee42c20b10 294 SUPERFAMILY SSF54631 86 224 4.3E-25 T 06-07-2017 LK06_RS00200 9ccad99b4ab41f3152eb62ee42c20b10 294 SMART SM00116 177 225 0.073 T 06-07-2017 IPR000644 CBS domain LK06_RS00200 9ccad99b4ab41f3152eb62ee42c20b10 294 SMART SM00116 94 142 3.2E-6 T 06-07-2017 IPR000644 CBS domain LK06_RS00200 9ccad99b4ab41f3152eb62ee42c20b10 294 Pfam PF04972 BON domain 227 292 3.8E-7 T 06-07-2017 IPR007055 BON domain LK06_RS00200 9ccad99b4ab41f3152eb62ee42c20b10 294 Pfam PF00571 CBS domain 87 140 1.1E-9 T 06-07-2017 IPR000644 CBS domain LK06_RS00200 9ccad99b4ab41f3152eb62ee42c20b10 294 Pfam PF00571 CBS domain 171 224 1.6E-7 T 06-07-2017 IPR000644 CBS domain LK06_RS19250 dcf5595b0bed7c9075603eb85d60b5de 324 SUPERFAMILY SSF53335 110 294 5.02E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19250 dcf5595b0bed7c9075603eb85d60b5de 324 Pfam PF01170 Putative RNA methylase family UPF0020 112 238 1.0E-7 T 06-07-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS19250 dcf5595b0bed7c9075603eb85d60b5de 324 Gene3D G3DSA:3.40.50.150 106 161 1.2E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19250 dcf5595b0bed7c9075603eb85d60b5de 324 Gene3D G3DSA:3.40.50.150 200 284 1.2E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS13020 8ce0667fef60c01ca6dbe4ad95d15f9d 209 Pfam PF13649 Methyltransferase domain 46 136 2.6E-19 T 06-07-2017 LK06_RS13020 8ce0667fef60c01ca6dbe4ad95d15f9d 209 Gene3D G3DSA:3.40.50.150 4 183 2.2E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS13020 8ce0667fef60c01ca6dbe4ad95d15f9d 209 SUPERFAMILY SSF53335 5 207 5.93E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS02005 ebd51cc7436e988958468a03da03ad17 832 Gene3D G3DSA:1.25.20.10 384 534 2.0E-4 T 06-07-2017 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 LK06_RS02005 ebd51cc7436e988958468a03da03ad17 832 SMART SM00530 57 113 9.3E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS02005 ebd51cc7436e988958468a03da03ad17 832 Gene3D G3DSA:1.10.260.40 49 108 1.5E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS02005 ebd51cc7436e988958468a03da03ad17 832 Pfam PF13560 Helix-turn-helix domain 53 115 1.9E-12 T 06-07-2017 LK06_RS02005 ebd51cc7436e988958468a03da03ad17 832 SUPERFAMILY SSF47413 51 109 1.8E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS07105 74d969bf4e67874a41738f28cb742134 495 Pfam PF00425 chorismate binding enzyme 227 479 1.7E-99 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal LK06_RS07105 74d969bf4e67874a41738f28cb742134 495 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 168 8.4E-30 T 06-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS07105 74d969bf4e67874a41738f28cb742134 495 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 25 488 2.0E-174 T 06-07-2017 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS07105 74d969bf4e67874a41738f28cb742134 495 PRINTS PR00095 Anthranilate synthase component I signature 341 354 1.0E-23 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS07105 74d969bf4e67874a41738f28cb742134 495 PRINTS PR00095 Anthranilate synthase component I signature 421 435 1.0E-23 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS07105 74d969bf4e67874a41738f28cb742134 495 PRINTS PR00095 Anthranilate synthase component I signature 436 450 1.0E-23 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS07105 74d969bf4e67874a41738f28cb742134 495 PRINTS PR00095 Anthranilate synthase component I signature 327 340 1.0E-23 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS07105 74d969bf4e67874a41738f28cb742134 495 Gene3D G3DSA:3.60.120.10 13 490 4.4E-174 T 06-07-2017 IPR005801 ADC synthase GO:0009058 LK06_RS07105 74d969bf4e67874a41738f28cb742134 495 SUPERFAMILY SSF56322 14 488 2.88E-156 T 06-07-2017 IPR005801 ADC synthase GO:0009058 LK06_RS16950 534e21effe7e451c27b773f5901f396d 775 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 236 364 4.1E-13 T 06-07-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 LK06_RS16950 534e21effe7e451c27b773f5901f396d 775 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 5 363 6.0E-116 T 06-07-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 LK06_RS16950 534e21effe7e451c27b773f5901f396d 775 Gene3D G3DSA:1.10.8.60 168 245 4.4E-20 T 06-07-2017 LK06_RS16950 534e21effe7e451c27b773f5901f396d 775 SUPERFAMILY SSF48019 247 365 1.45E-21 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 LK06_RS16950 534e21effe7e451c27b773f5901f396d 775 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.8E-38 T 06-07-2017 LK06_RS16950 534e21effe7e451c27b773f5901f396d 775 Gene3D G3DSA:1.20.272.10 246 364 3.7E-14 T 06-07-2017 LK06_RS16950 534e21effe7e451c27b773f5901f396d 775 SMART SM00382 37 181 8.7E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS16950 534e21effe7e451c27b773f5901f396d 775 SUPERFAMILY SSF52540 32 222 4.91E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16950 534e21effe7e451c27b773f5901f396d 775 Gene3D G3DSA:3.40.50.300 15 167 1.3E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28370 66adbd904da7068b933353ac5212b241 734 SUPERFAMILY SSF53756 24 391 7.85E-17 T 06-07-2017 LK06_RS28370 66adbd904da7068b933353ac5212b241 734 SUPERFAMILY SSF53756 414 731 1.26E-27 T 06-07-2017 LK06_RS28370 66adbd904da7068b933353ac5212b241 734 Pfam PF13439 Glycosyltransferase Family 4 442 540 2.3E-8 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS10170 61b1c52192e20320fedc4837d1003f10 548 SMART SM00240 459 519 5.7E-5 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS10170 61b1c52192e20320fedc4837d1003f10 548 Pfam PF00498 FHA domain 460 538 1.6E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS10170 61b1c52192e20320fedc4837d1003f10 548 SUPERFAMILY SSF49879 400 543 1.68E-22 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS10170 61b1c52192e20320fedc4837d1003f10 548 Gene3D G3DSA:2.60.200.20 454 542 3.5E-20 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS13625 85324bc2ab40f0ca403e0ec19c96ad1c 451 SMART SM00388 225 283 3.9E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13625 85324bc2ab40f0ca403e0ec19c96ad1c 451 Pfam PF00672 HAMP domain 149 221 9.7E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS13625 85324bc2ab40f0ca403e0ec19c96ad1c 451 SMART SM00387 321 434 1.3E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13625 85324bc2ab40f0ca403e0ec19c96ad1c 451 SMART SM00304 168 224 6.3E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS13625 85324bc2ab40f0ca403e0ec19c96ad1c 451 Gene3D G3DSA:3.30.565.10 271 431 5.8E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13625 85324bc2ab40f0ca403e0ec19c96ad1c 451 Gene3D G3DSA:1.10.287.130 215 270 1.7E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13625 85324bc2ab40f0ca403e0ec19c96ad1c 451 SUPERFAMILY SSF47384 208 281 1.75E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13625 85324bc2ab40f0ca403e0ec19c96ad1c 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 432 1.2E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13625 85324bc2ab40f0ca403e0ec19c96ad1c 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 226 282 2.5E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS13625 85324bc2ab40f0ca403e0ec19c96ad1c 451 SUPERFAMILY SSF55874 273 432 9.43E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01770 b21ab8eeb773344de3151dcbe5bba061 403 SMART SM00257 190 239 1.9E-4 T 06-07-2017 IPR018392 LysM domain LK06_RS01770 b21ab8eeb773344de3151dcbe5bba061 403 SUPERFAMILY SSF54106 189 238 2.22E-5 T 06-07-2017 IPR018392 LysM domain LK06_RS01770 b21ab8eeb773344de3151dcbe5bba061 403 SUPERFAMILY SSF51261 265 396 1.26E-40 T 06-07-2017 IPR011055 Duplicated hybrid motif LK06_RS01770 b21ab8eeb773344de3151dcbe5bba061 403 Gene3D G3DSA:2.70.70.10 253 397 1.4E-40 T 06-07-2017 LK06_RS01770 b21ab8eeb773344de3151dcbe5bba061 403 Gene3D G3DSA:1.10.530.10 22 123 1.5E-43 T 06-07-2017 LK06_RS01770 b21ab8eeb773344de3151dcbe5bba061 403 SUPERFAMILY SSF53955 42 123 7.43E-34 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS01770 b21ab8eeb773344de3151dcbe5bba061 403 Pfam PF06737 Transglycosylase-like domain 41 117 5.5E-36 T 06-07-2017 IPR010618 Transglycosylase-like LK06_RS01770 b21ab8eeb773344de3151dcbe5bba061 403 Pfam PF01551 Peptidase family M23 295 382 8.0E-30 T 06-07-2017 IPR016047 Peptidase M23 LK06_RS01770 b21ab8eeb773344de3151dcbe5bba061 403 Pfam PF01476 LysM domain 191 238 1.2E-4 T 06-07-2017 IPR018392 LysM domain LK06_RS01770 b21ab8eeb773344de3151dcbe5bba061 403 Gene3D G3DSA:3.10.350.10 189 238 4.2E-8 T 06-07-2017 IPR018392 LysM domain LK06_RS29105 422282703f6e61dc9b7f64f589bad584 311 Pfam PF00171 Aldehyde dehydrogenase family 29 269 4.9E-70 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS29105 422282703f6e61dc9b7f64f589bad584 311 Gene3D G3DSA:3.40.605.10 29 60 7.5E-7 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS29105 422282703f6e61dc9b7f64f589bad584 311 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 47 54 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 LK06_RS29105 422282703f6e61dc9b7f64f589bad584 311 Gene3D G3DSA:3.40.309.10 61 245 1.4E-52 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS29105 422282703f6e61dc9b7f64f589bad584 311 SUPERFAMILY SSF53720 29 272 6.81E-71 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS05830 f75d1937869df410fe8a94e7a86696bd 190 Gene3D G3DSA:3.10.300.10 58 185 6.5E-30 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 LK06_RS05830 f75d1937869df410fe8a94e7a86696bd 190 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 54 175 2.4E-27 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 LK06_RS05830 f75d1937869df410fe8a94e7a86696bd 190 SUPERFAMILY SSF50486 55 183 3.37E-24 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 LK06_RS20330 794d373d495568db0290722e98c8c096 392 Pfam PF00549 CoA-ligase 257 377 4.1E-14 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS20330 794d373d495568db0290722e98c8c096 392 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 389 1.3E-123 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LK06_RS20330 794d373d495568db0290722e98c8c096 392 PIRSF PIRSF001554 1 392 4.1E-136 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LK06_RS20330 794d373d495568db0290722e98c8c096 392 Pfam PF08442 ATP-grasp domain 2 195 1.4E-66 T 06-07-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LK06_RS20330 794d373d495568db0290722e98c8c096 392 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 250 274 - T 06-07-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS20330 794d373d495568db0290722e98c8c096 392 Gene3D G3DSA:3.40.50.261 233 389 1.2E-52 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS20330 794d373d495568db0290722e98c8c096 392 Gene3D G3DSA:3.30.1490.20 22 85 3.2E-17 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS20330 794d373d495568db0290722e98c8c096 392 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 390 41.121 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LK06_RS20330 794d373d495568db0290722e98c8c096 392 Gene3D G3DSA:3.30.470.20 86 229 1.8E-49 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS20330 794d373d495568db0290722e98c8c096 392 SUPERFAMILY SSF56059 3 228 9.03E-63 T 06-07-2017 LK06_RS20330 794d373d495568db0290722e98c8c096 392 SUPERFAMILY SSF52210 232 389 5.36E-42 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS04925 45546b7965d988fb6a06d38e597aaa25 496 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 362 371 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS04925 45546b7965d988fb6a06d38e597aaa25 496 Gene3D G3DSA:1.10.630.10 28 425 7.4E-86 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS04925 45546b7965d988fb6a06d38e597aaa25 496 SUPERFAMILY SSF48264 31 423 2.23E-61 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS04925 45546b7965d988fb6a06d38e597aaa25 496 PRINTS PR00359 B-class P450 signature 360 369 2.1E-20 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS04925 45546b7965d988fb6a06d38e597aaa25 496 PRINTS PR00359 B-class P450 signature 313 340 2.1E-20 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS04925 45546b7965d988fb6a06d38e597aaa25 496 PRINTS PR00359 B-class P450 signature 166 182 2.1E-20 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS04925 45546b7965d988fb6a06d38e597aaa25 496 PRINTS PR00359 B-class P450 signature 120 131 2.1E-20 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS04925 45546b7965d988fb6a06d38e597aaa25 496 PRINTS PR00359 B-class P450 signature 217 239 2.1E-20 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS23740 fffbf07de14306d4b06e88cd166366d5 421 Gene3D G3DSA:3.40.640.10 37 283 1.3E-104 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS23740 fffbf07de14306d4b06e88cd166366d5 421 Gene3D G3DSA:3.90.1150.10 284 417 1.7E-46 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS23740 fffbf07de14306d4b06e88cd166366d5 421 SUPERFAMILY SSF53383 3 418 2.88E-170 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS23740 fffbf07de14306d4b06e88cd166366d5 421 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 49.83 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS23740 fffbf07de14306d4b06e88cd166366d5 421 PIRSF PIRSF000412 1 414 3.1E-155 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS23740 fffbf07de14306d4b06e88cd166366d5 421 Pfam PF00464 Serine hydroxymethyltransferase 9 389 1.4E-159 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS23740 fffbf07de14306d4b06e88cd166366d5 421 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 06-07-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LK06_RS23745 10407b4e3dbcb414bc8c880793f91514 125 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 LK06_RS23745 10407b4e3dbcb414bc8c880793f91514 125 SUPERFAMILY SSF51230 4 122 1.44E-38 T 06-07-2017 IPR011053 Single hybrid motif LK06_RS23745 10407b4e3dbcb414bc8c880793f91514 125 Pfam PF01597 Glycine cleavage H-protein 7 121 3.9E-41 T 06-07-2017 IPR002930 Glycine cleavage system H-protein LK06_RS23745 10407b4e3dbcb414bc8c880793f91514 125 Gene3D G3DSA:2.40.50.100 6 123 1.8E-44 T 06-07-2017 LK06_RS23745 10407b4e3dbcb414bc8c880793f91514 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 121 1.1E-43 T 06-07-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 LK06_RS23745 10407b4e3dbcb414bc8c880793f91514 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 29.186 T 06-07-2017 IPR002930 Glycine cleavage system H-protein LK06_RS12935 1e8a6f3aaeccb18244f50bcc0d6163b8 306 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 35 177 2.6E-49 T 06-07-2017 LK06_RS12935 1e8a6f3aaeccb18244f50bcc0d6163b8 306 SUPERFAMILY SSF52833 33 187 2.12E-47 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS12935 1e8a6f3aaeccb18244f50bcc0d6163b8 306 Gene3D G3DSA:3.40.30.10 98 184 8.8E-9 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS12935 1e8a6f3aaeccb18244f50bcc0d6163b8 306 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 35 177 1.7E-44 T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS21995 81af2f0808cf69e868be706d8a757e92 286 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS21995 81af2f0808cf69e868be706d8a757e92 286 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS21995 81af2f0808cf69e868be706d8a757e92 286 SUPERFAMILY SSF51717 4 276 8.5E-82 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS21995 81af2f0808cf69e868be706d8a757e92 286 Pfam PF00809 Pterin binding enzyme 17 257 6.6E-65 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS21995 81af2f0808cf69e868be706d8a757e92 286 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 271 9.4E-82 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 LK06_RS21995 81af2f0808cf69e868be706d8a757e92 286 Gene3D G3DSA:3.20.20.20 13 274 1.4E-84 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS22430 4505a475a1f4b02cc9c3ae076ac5c541 168 Gene3D G3DSA:3.40.630.30 1 148 2.1E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS22430 4505a475a1f4b02cc9c3ae076ac5c541 168 SUPERFAMILY SSF55729 1 147 2.44E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS22430 4505a475a1f4b02cc9c3ae076ac5c541 168 Pfam PF00583 Acetyltransferase (GNAT) family 58 142 4.6E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 Pfam PF02839 Carbohydrate binding domain 412 454 1.8E-8 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 SMART SM00495 411 457 1.4E-12 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 Gene3D G3DSA:2.40.10.10 294 382 2.1E-31 T 06-07-2017 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 SUPERFAMILY SSF50494 210 391 1.5E-35 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 Pfam PF02983 Alpha-lytic protease prodomain 134 191 5.3E-18 T 06-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 345 356 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 Gene3D G3DSA:3.30.300.50 134 202 2.3E-18 T 06-07-2017 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 SUPERFAMILY SSF51055 414 456 1.83E-15 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 Gene3D G3DSA:2.40.10.10 210 293 1.6E-27 T 06-07-2017 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 Gene3D G3DSA:2.10.10.20 413 457 7.4E-23 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 Gene3D G3DSA:3.30.300.50 52 132 6.3E-29 T 06-07-2017 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 236 250 3.4E-44 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 336 359 3.4E-44 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 296 316 3.4E-44 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 360 374 3.4E-44 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS12375 ffcc54b98186acf3b164df9b8b575b30 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 317 334 3.4E-44 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 LK06_RS11570 eda40deb15736bea87cfd69b49c38213 372 Gene3D G3DSA:2.30.42.10 93 179 8.1E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS11570 eda40deb15736bea87cfd69b49c38213 372 Gene3D G3DSA:3.90.226.10 180 354 6.2E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS11570 eda40deb15736bea87cfd69b49c38213 372 SMART SM00228 70 170 2.5E-6 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS11570 eda40deb15736bea87cfd69b49c38213 372 SUPERFAMILY SSF52096 171 354 1.36E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS11570 eda40deb15736bea87cfd69b49c38213 372 SUPERFAMILY SSF52096 51 86 1.36E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS11570 eda40deb15736bea87cfd69b49c38213 372 SUPERFAMILY SSF50156 69 184 3.68E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS11570 eda40deb15736bea87cfd69b49c38213 372 SMART SM00245 170 354 7.0E-39 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LK06_RS11570 eda40deb15736bea87cfd69b49c38213 372 Pfam PF13180 PDZ domain 96 171 1.4E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS11570 eda40deb15736bea87cfd69b49c38213 372 Pfam PF03572 Peptidase family S41 198 352 1.2E-38 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LK06_RS03740 80cbc9979bd6eb211f975e7f70b58c48 201 Gene3D G3DSA:3.40.50.300 15 188 2.7E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03740 80cbc9979bd6eb211f975e7f70b58c48 201 SUPERFAMILY SSF52540 19 175 7.43E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03740 80cbc9979bd6eb211f975e7f70b58c48 201 PRINTS PR00449 Transforming protein P21 ras signature 76 98 6.1E-5 T 06-07-2017 LK06_RS03740 80cbc9979bd6eb211f975e7f70b58c48 201 PRINTS PR00449 Transforming protein P21 ras signature 18 39 6.1E-5 T 06-07-2017 LK06_RS03740 80cbc9979bd6eb211f975e7f70b58c48 201 PRINTS PR00449 Transforming protein P21 ras signature 166 188 6.1E-5 T 06-07-2017 LK06_RS03740 80cbc9979bd6eb211f975e7f70b58c48 201 Pfam PF03029 Conserved hypothetical ATP binding protein 22 189 1.2E-26 T 06-07-2017 IPR004130 GPN-loop GTPase LK06_RS17240 cb4c7516b620af4f87ef2b0c725cd902 251 SUPERFAMILY SSF47413 3 42 1.13E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS17240 cb4c7516b620af4f87ef2b0c725cd902 251 Gene3D G3DSA:1.10.260.40 3 54 2.3E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS22390 5f69815b146f1a6674dca672d53c66e1 437 Gene3D G3DSA:1.10.3210.10 244 404 2.3E-23 T 06-07-2017 IPR006674 HD domain LK06_RS22390 5f69815b146f1a6674dca672d53c66e1 437 TIGRFAM TIGR00277 HDIG: HDIG domain 246 335 1.1E-8 T 06-07-2017 IPR006675 HDIG domain LK06_RS22390 5f69815b146f1a6674dca672d53c66e1 437 Pfam PF01966 HD domain 247 367 2.2E-21 T 06-07-2017 IPR006674 HD domain LK06_RS22390 5f69815b146f1a6674dca672d53c66e1 437 SMART SM00471 241 376 2.5E-12 T 06-07-2017 IPR003607 HD/PDEase domain LK06_RS22390 5f69815b146f1a6674dca672d53c66e1 437 SUPERFAMILY SSF109604 229 404 1.23E-39 T 06-07-2017 LK06_RS11170 1aef30b4d07bd24f916911e9c3d3b98a 433 Pfam PF02378 Phosphotransferase system, EIIC 26 355 1.1E-65 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 LK06_RS13265 4eca61d5ba9a56e1ae011a7e53935572 338 SUPERFAMILY SSF103481 65 155 3.79E-13 T 06-07-2017 LK06_RS13265 4eca61d5ba9a56e1ae011a7e53935572 338 SUPERFAMILY SSF103481 198 299 8.11E-12 T 06-07-2017 LK06_RS13265 4eca61d5ba9a56e1ae011a7e53935572 338 Pfam PF00892 EamA-like transporter family 163 294 6.6E-17 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS13265 4eca61d5ba9a56e1ae011a7e53935572 338 Pfam PF00892 EamA-like transporter family 28 152 4.1E-13 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS21495 d22d0cfc4327b3a147159493a5eb35a6 196 SUPERFAMILY SSF55469 13 195 4.71E-37 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS21495 d22d0cfc4327b3a147159493a5eb35a6 196 Gene3D G3DSA:3.40.109.10 13 194 4.9E-37 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS21495 d22d0cfc4327b3a147159493a5eb35a6 196 Pfam PF00881 Nitroreductase family 15 173 9.0E-17 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 LK06_RS01905 248f561857a6e44c3de22459825c5dae 432 Gene3D G3DSA:3.50.50.60 37 196 5.3E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01905 248f561857a6e44c3de22459825c5dae 432 Gene3D G3DSA:3.50.50.60 271 343 5.3E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01905 248f561857a6e44c3de22459825c5dae 432 Pfam PF05834 Lycopene cyclase protein 38 417 5.2E-96 T 06-07-2017 LK06_RS01905 248f561857a6e44c3de22459825c5dae 432 SUPERFAMILY SSF51905 36 208 3.0E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01905 248f561857a6e44c3de22459825c5dae 432 SUPERFAMILY SSF51905 293 360 3.0E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS23390 1cad4fc921479510fe1f4705913b9707 342 SUPERFAMILY SSF51679 1 342 1.88E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS23390 1cad4fc921479510fe1f4705913b9707 342 Gene3D G3DSA:3.20.20.30 1 342 4.9E-88 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS23390 1cad4fc921479510fe1f4705913b9707 342 Pfam PF00296 Luciferase-like monooxygenase 1 311 5.3E-53 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS16800 daee5393ef37c61133552f9b5b0aa530 149 SUPERFAMILY SSF56349 17 125 5.59E-18 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS16800 daee5393ef37c61133552f9b5b0aa530 149 Pfam PF00589 Phage integrase family 34 102 1.8E-8 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS16800 daee5393ef37c61133552f9b5b0aa530 149 Gene3D G3DSA:1.10.443.10 12 125 1.0E-16 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS29100 915e9e997ab27fdca28abc5919de0dc0 415 Pfam PF01610 Transposase 160 400 2.0E-74 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain LK06_RS29100 915e9e997ab27fdca28abc5919de0dc0 415 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 94 142 1.7E-7 T 06-07-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain LK06_RS14860 7ac2aeda52da4123147477726d0a8688 266 Gene3D G3DSA:1.20.1260.10 140 263 1.2E-28 T 06-07-2017 IPR012347 Ferritin-related LK06_RS14860 7ac2aeda52da4123147477726d0a8688 266 SUPERFAMILY SSF47240 142 264 1.02E-24 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS14860 7ac2aeda52da4123147477726d0a8688 266 SUPERFAMILY SSF47240 2 116 2.18E-24 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS14860 7ac2aeda52da4123147477726d0a8688 266 Gene3D G3DSA:1.20.1260.10 2 117 1.9E-28 T 06-07-2017 IPR012347 Ferritin-related LK06_RS14860 7ac2aeda52da4123147477726d0a8688 266 Pfam PF02915 Rubrerythrin 187 261 4.6E-9 T 06-07-2017 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 LK06_RS14860 7ac2aeda52da4123147477726d0a8688 266 Pfam PF02915 Rubrerythrin 37 110 2.5E-10 T 06-07-2017 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 Pfam PF07690 Major Facilitator Superfamily 27 422 4.6E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 435 3.2E-76 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 Gene3D G3DSA:1.20.1250.20 20 207 1.6E-29 T 06-07-2017 LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 Gene3D G3DSA:1.20.1250.20 274 489 6.4E-16 T 06-07-2017 LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 26 50 2.5E-6 T 06-07-2017 LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 2.5E-6 T 06-07-2017 LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 214 232 2.5E-6 T 06-07-2017 LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 SUPERFAMILY SSF103473 18 207 1.44E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 SUPERFAMILY SSF103473 259 432 1.44E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS19265 e08a1babd886a60da6264e02c714da59 512 SUPERFAMILY SSF103473 461 490 1.44E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS23795 3472876b06c4f97864462529a361d072 219 Pfam PF03458 UPF0126 domain 14 88 5.4E-20 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 LK06_RS23795 3472876b06c4f97864462529a361d072 219 Pfam PF03458 UPF0126 domain 100 174 2.0E-19 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 SUPERFAMILY SSF54373 177 275 1.47E-7 T 06-07-2017 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 Gene3D G3DSA:3.50.50.60 3 178 1.0E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 Gene3D G3DSA:3.50.50.60 270 349 1.0E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 SUPERFAMILY SSF51905 270 362 3.31E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 SUPERFAMILY SSF51905 3 172 3.31E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 1.2E-12 T 06-07-2017 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.2E-12 T 06-07-2017 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.2E-12 T 06-07-2017 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 1.2E-12 T 06-07-2017 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 Pfam PF01494 FAD binding domain 266 343 6.7E-6 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS26375 694b5d3f1a222ef5c4c44c73e4bb3c16 404 Pfam PF01494 FAD binding domain 3 169 2.1E-12 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS03245 a87b2d2621a2873115a8e1941d901a00 381 Pfam PF00067 Cytochrome P450 247 348 2.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS03245 a87b2d2621a2873115a8e1941d901a00 381 Gene3D G3DSA:1.10.630.10 4 370 2.5E-53 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS03245 a87b2d2621a2873115a8e1941d901a00 381 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 316 325 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS03245 a87b2d2621a2873115a8e1941d901a00 381 PRINTS PR00359 B-class P450 signature 247 258 5.3E-18 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS03245 a87b2d2621a2873115a8e1941d901a00 381 PRINTS PR00359 B-class P450 signature 264 291 5.3E-18 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS03245 a87b2d2621a2873115a8e1941d901a00 381 PRINTS PR00359 B-class P450 signature 323 334 5.3E-18 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS03245 a87b2d2621a2873115a8e1941d901a00 381 PRINTS PR00359 B-class P450 signature 71 82 5.3E-18 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS03245 a87b2d2621a2873115a8e1941d901a00 381 PRINTS PR00359 B-class P450 signature 134 149 5.3E-18 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS03245 a87b2d2621a2873115a8e1941d901a00 381 PRINTS PR00359 B-class P450 signature 314 323 5.3E-18 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS03245 a87b2d2621a2873115a8e1941d901a00 381 SUPERFAMILY SSF48264 12 368 5.11E-45 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02310 a643fd37725d5ad2356d77e864199d4b 103 SUPERFAMILY SSF51278 1 102 3.92E-43 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02310 a643fd37725d5ad2356d77e864199d4b 103 Gene3D G3DSA:2.10.150.10 1 102 3.3E-45 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02310 a643fd37725d5ad2356d77e864199d4b 103 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 30.028 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02310 a643fd37725d5ad2356d77e864199d4b 103 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 2.1E-37 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02310 a643fd37725d5ad2356d77e864199d4b 103 Pfam PF00699 Urease beta subunit 3 99 1.0E-39 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS30905 fa71a76c390734fdebfa351d6b0e98a5 557 Gene3D G3DSA:3.50.50.60 2 274 5.8E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30905 fa71a76c390734fdebfa351d6b0e98a5 557 Gene3D G3DSA:3.50.50.60 490 555 5.8E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30905 fa71a76c390734fdebfa351d6b0e98a5 557 Pfam PF00890 FAD binding domain 4 538 1.7E-111 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS30905 fa71a76c390734fdebfa351d6b0e98a5 557 SUPERFAMILY SSF51905 2 279 1.37E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30905 fa71a76c390734fdebfa351d6b0e98a5 557 SUPERFAMILY SSF51905 493 555 1.37E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30905 fa71a76c390734fdebfa351d6b0e98a5 557 PIRSF PIRSF036654 1 556 2.7E-298 T 06-07-2017 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 LK06_RS09515 8fc60a78ff93f249be35163337114aa8 410 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 32 367 3.1E-73 T 06-07-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 LK06_RS09515 8fc60a78ff93f249be35163337114aa8 410 SMART SM00729 29 259 6.0E-61 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS09515 8fc60a78ff93f249be35163337114aa8 410 Gene3D G3DSA:3.80.30.20 32 274 1.9E-37 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe LK06_RS09515 8fc60a78ff93f249be35163337114aa8 410 Pfam PF04055 Radical SAM superfamily 35 213 5.2E-19 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS09515 8fc60a78ff93f249be35163337114aa8 410 SUPERFAMILY SSF102114 20 408 4.45E-108 T 06-07-2017 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 Pfam PF03129 Anticodon binding domain 366 453 6.5E-24 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 458 49.514 T 06-07-2017 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 SUPERFAMILY SSF52954 353 457 1.3E-34 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 SUPERFAMILY SSF55681 5 369 6.49E-122 T 06-07-2017 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 Gene3D G3DSA:3.40.50.800 363 455 8.2E-40 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 403 422 2.2E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 2.2E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 317 329 2.2E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 190 207 2.2E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 137 149 2.2E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 207 217 2.2E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 158 175 2.2E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 157 333 4.2E-9 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 Gene3D G3DSA:3.30.930.10 7 362 1.2E-143 T 06-07-2017 LK06_RS09290 e44b4b12b4705da97f4573fcf3e720ae 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 230 1.5E-82 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LK06_RS26125 74c8ce19510a8bf9bd3f9094c566b4d3 332 SUPERFAMILY SSF161098 88 317 7.19E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26125 74c8ce19510a8bf9bd3f9094c566b4d3 332 Gene3D G3DSA:1.10.3720.10 38 318 1.3E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26125 74c8ce19510a8bf9bd3f9094c566b4d3 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 319 1.2E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS28330 8764608391915a95f140e750a23c0693 219 Pfam PF00925 GTP cyclohydrolase II 19 185 1.2E-64 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS28330 8764608391915a95f140e750a23c0693 219 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 16 211 41.228 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS28330 8764608391915a95f140e750a23c0693 219 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 19 209 3.1E-69 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS28330 8764608391915a95f140e750a23c0693 219 SUPERFAMILY SSF142695 19 188 3.92E-60 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS01915 a8e81c9d2a1378c8304a9d6845f0544b 168 PIRSF PIRSF005859 14 168 1.3E-36 T 06-07-2017 IPR004307 TspO/MBR-related protein GO:0016021 LK06_RS01915 a8e81c9d2a1378c8304a9d6845f0544b 168 Pfam PF03073 TspO/MBR family 23 164 2.7E-36 T 06-07-2017 IPR004307 TspO/MBR-related protein GO:0016021 LK06_RS27940 0007516e53b2368d5dd6e528131e179c 275 Pfam PF03631 Virulence factor BrkB 2 225 3.6E-9 T 06-07-2017 IPR017039 Virulence factor BrkB LK06_RS13060 cb22a621cdb93876a5bc70a1fbebad79 224 Pfam PF02441 Flavoprotein 11 156 2.4E-22 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS13060 cb22a621cdb93876a5bc70a1fbebad79 224 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 9 215 30.139 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 LK06_RS13060 cb22a621cdb93876a5bc70a1fbebad79 224 SUPERFAMILY SSF52507 12 215 2.75E-43 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS13060 cb22a621cdb93876a5bc70a1fbebad79 224 Gene3D G3DSA:3.40.50.1950 11 216 6.0E-62 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS13060 cb22a621cdb93876a5bc70a1fbebad79 224 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 90 213 2.8E-33 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 LK06_RS19660 f609afdf8e4c2edf0b9bb33f7701414c 253 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 21 214 6.3E-51 T 06-07-2017 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 LK06_RS19660 f609afdf8e4c2edf0b9bb33f7701414c 253 Pfam PF02361 Cobalt transport protein 15 218 9.5E-33 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component LK06_RS10815 bab810223149070feb048d13d4321a2e 341 Gene3D G3DSA:1.10.3720.10 50 329 1.0E-56 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10815 bab810223149070feb048d13d4321a2e 341 SUPERFAMILY SSF161098 97 327 1.31E-58 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10815 bab810223149070feb048d13d4321a2e 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 337 5.6E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS03270 bb808cf7314b3b2b481a9868ae2b7552 415 Pfam PF00668 Condensation domain 2 286 7.0E-39 T 06-07-2017 IPR001242 Condensation domain LK06_RS03270 bb808cf7314b3b2b481a9868ae2b7552 415 SUPERFAMILY SSF52777 176 412 7.45E-34 T 06-07-2017 LK06_RS03270 bb808cf7314b3b2b481a9868ae2b7552 415 SUPERFAMILY SSF52777 7 175 5.56E-32 T 06-07-2017 LK06_RS17875 2d133871d673899d470403500059d697 177 Pfam PF02542 YgbB family 23 173 2.6E-44 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LK06_RS17875 2d133871d673899d470403500059d697 177 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 22 175 30.724 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LK06_RS17875 2d133871d673899d470403500059d697 177 SUPERFAMILY SSF69765 21 175 1.57E-48 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LK06_RS17875 2d133871d673899d470403500059d697 177 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 23 174 6.1E-42 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LK06_RS17875 2d133871d673899d470403500059d697 177 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 57 72 - T 06-07-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LK06_RS17875 2d133871d673899d470403500059d697 177 Gene3D G3DSA:3.30.1330.50 22 175 2.4E-52 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LK06_RS06235 5a9316b4290f779f66321740f2ad8e66 502 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 479 1.0E-134 T 06-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 LK06_RS06235 5a9316b4290f779f66321740f2ad8e66 502 Gene3D G3DSA:3.40.50.300 5 237 6.0E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06235 5a9316b4290f779f66321740f2ad8e66 502 SUPERFAMILY SSF52540 5 241 8.58E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06235 5a9316b4290f779f66321740f2ad8e66 502 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 226 1.4E-25 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain LK06_RS06235 5a9316b4290f779f66321740f2ad8e66 502 SUPERFAMILY SSF52317 261 428 6.45E-34 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS06235 5a9316b4290f779f66321740f2ad8e66 502 Gene3D G3DSA:3.40.50.880 262 444 1.0E-37 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS06235 5a9316b4290f779f66321740f2ad8e66 502 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 488 170.371 T 06-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 LK06_RS06235 5a9316b4290f779f66321740f2ad8e66 502 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 262 431 4.7E-42 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 LK06_RS00185 e54b7f3448a103937748cd4ce8f847d6 301 Gene3D G3DSA:3.40.50.620 1 138 2.2E-34 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS00185 e54b7f3448a103937748cd4ce8f847d6 301 Gene3D G3DSA:3.40.50.620 157 298 4.4E-24 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS00185 e54b7f3448a103937748cd4ce8f847d6 301 Pfam PF00582 Universal stress protein family 161 298 6.1E-19 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS00185 e54b7f3448a103937748cd4ce8f847d6 301 Pfam PF00582 Universal stress protein family 2 138 5.8E-27 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS00185 e54b7f3448a103937748cd4ce8f847d6 301 SUPERFAMILY SSF52402 3 140 3.43E-31 T 06-07-2017 LK06_RS00185 e54b7f3448a103937748cd4ce8f847d6 301 SUPERFAMILY SSF52402 161 298 8.04E-20 T 06-07-2017 LK06_RS00185 e54b7f3448a103937748cd4ce8f847d6 301 PRINTS PR01438 Universal stress protein signature 2 20 5.0E-14 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00185 e54b7f3448a103937748cd4ce8f847d6 301 PRINTS PR01438 Universal stress protein signature 98 110 5.0E-14 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00185 e54b7f3448a103937748cd4ce8f847d6 301 PRINTS PR01438 Universal stress protein signature 116 138 5.0E-14 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS01520 7889c8b9c54374963145fac9c566dddf 148 SUPERFAMILY SSF50118 41 147 2.62E-9 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor LK06_RS01520 7889c8b9c54374963145fac9c566dddf 148 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 43 143 1.3E-11 T 06-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 LK06_RS01520 7889c8b9c54374963145fac9c566dddf 148 Gene3D G3DSA:2.30.30.110 41 142 1.8E-4 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor LK06_RS14465 d7fd968fd659c3d595d04145e6187c15 597 Pfam PF00326 Prolyl oligopeptidase family 387 589 6.1E-40 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 LK06_RS14465 d7fd968fd659c3d595d04145e6187c15 597 SUPERFAMILY SSF53474 342 588 2.27E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS14465 d7fd968fd659c3d595d04145e6187c15 597 Gene3D G3DSA:3.40.50.1820 34 73 2.7E-70 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS14465 d7fd968fd659c3d595d04145e6187c15 597 Gene3D G3DSA:3.40.50.1820 327 588 2.7E-70 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS14465 d7fd968fd659c3d595d04145e6187c15 597 SUPERFAMILY SSF82171 26 316 3.33E-25 T 06-07-2017 LK06_RS14465 d7fd968fd659c3d595d04145e6187c15 597 Gene3D G3DSA:2.120.10.30 103 305 1.9E-15 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like LK06_RS28310 a8883e03ff12e279a202b405eb72f19c 385 Pfam PF00534 Glycosyl transferases group 1 196 355 9.8E-31 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS28310 a8883e03ff12e279a202b405eb72f19c 385 SUPERFAMILY SSF53756 34 377 1.61E-56 T 06-07-2017 LK06_RS28310 a8883e03ff12e279a202b405eb72f19c 385 Gene3D G3DSA:3.40.50.2000 191 354 3.0E-25 T 06-07-2017 LK06_RS28845 ffca3e582a5ab60ea9e9287940e3604b 397 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 6 394 9.8E-194 T 06-07-2017 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 LK06_RS28845 ffca3e582a5ab60ea9e9287940e3604b 397 Gene3D G3DSA:3.90.1150.10 280 391 4.5E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS28845 ffca3e582a5ab60ea9e9287940e3604b 397 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 242 251 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 LK06_RS28845 ffca3e582a5ab60ea9e9287940e3604b 397 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 396 54.439 T 06-07-2017 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 LK06_RS28845 ffca3e582a5ab60ea9e9287940e3604b 397 SUPERFAMILY SSF53383 7 392 7.58E-118 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS28845 ffca3e582a5ab60ea9e9287940e3604b 397 Pfam PF00155 Aminotransferase class I and II 46 388 1.6E-68 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS28845 ffca3e582a5ab60ea9e9287940e3604b 397 Gene3D G3DSA:3.40.640.10 63 279 9.5E-88 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS22780 53ed7468095b80746fbb45667c6d8217 168 SUPERFAMILY SSF52799 13 154 1.29E-19 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like LK06_RS22780 53ed7468095b80746fbb45667c6d8217 168 Pfam PF00782 Dual specificity phosphatase, catalytic domain 97 151 2.9E-7 T 06-07-2017 IPR000340 Dual specificity phosphatase, catalytic domain GO:0006470|GO:0008138 LK06_RS22780 53ed7468095b80746fbb45667c6d8217 168 Gene3D G3DSA:3.90.190.10 12 154 3.3E-15 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 Pfam PF00128 Alpha amylase, catalytic domain 189 277 2.0E-6 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 Gene3D G3DSA:2.60.40.1180 587 700 9.6E-32 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 SUPERFAMILY SSF81296 5 147 9.52E-42 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 Gene3D G3DSA:3.20.20.80 152 573 3.7E-118 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 SUPERFAMILY SSF51445 499 573 3.55E-130 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 SUPERFAMILY SSF51445 133 470 3.55E-130 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 3.0E-16 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 SMART SM00642 177 565 2.0E-7 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 699 4.4E-299 T 06-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 Gene3D G3DSA:2.60.40.10 5 151 1.5E-52 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS26875 fdfcc6651109f65029a3d787981fb49b 702 SUPERFAMILY SSF51011 588 699 1.15E-23 T 06-07-2017 LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 SMART SM00052 1 215 1.1E-8 T 06-07-2017 IPR001633 EAL domain LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 Pfam PF00571 CBS domain 314 363 0.0027 T 06-07-2017 IPR000644 CBS domain LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 SUPERFAMILY SSF141868 6 215 6.02E-32 T 06-07-2017 IPR001633 EAL domain LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 383 468 7.1E-15 T 06-07-2017 IPR000160 GGDEF domain LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 SUPERFAMILY SSF55073 376 498 5.49E-19 T 06-07-2017 IPR029787 Nucleotide cyclase LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 Gene3D G3DSA:3.20.20.450 7 214 1.2E-23 T 06-07-2017 IPR001633 EAL domain LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 SMART SM00267 360 520 5.3E-9 T 06-07-2017 IPR000160 GGDEF domain LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 Pfam PF00563 EAL domain 6 210 2.2E-27 T 06-07-2017 IPR001633 EAL domain LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 Gene3D G3DSA:3.10.580.10 248 364 2.6E-5 T 06-07-2017 LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 Pfam PF00990 Diguanylate cyclase, GGDEF domain 375 460 7.6E-14 T 06-07-2017 IPR000160 GGDEF domain LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 Gene3D G3DSA:3.30.70.270 375 465 3.0E-20 T 06-07-2017 LK06_RS03730 04e9708e4b02bb46583931435e224ce1 550 SUPERFAMILY SSF54631 243 379 6.74E-8 T 06-07-2017 LK06_RS11445 15370541c0abe9d13d081fb4c0218da9 770 Pfam PF13538 UvrD-like helicase C-terminal domain 710 752 3.3E-8 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain LK06_RS11445 15370541c0abe9d13d081fb4c0218da9 770 Gene3D G3DSA:3.40.50.300 614 754 9.1E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11445 15370541c0abe9d13d081fb4c0218da9 770 Pfam PF00580 UvrD/REP helicase N-terminal domain 538 588 1.2E-6 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 LK06_RS11445 15370541c0abe9d13d081fb4c0218da9 770 Pfam PF13245 Part of AAA domain 237 293 1.9E-13 T 06-07-2017 LK06_RS11445 15370541c0abe9d13d081fb4c0218da9 770 SUPERFAMILY SSF52540 494 757 6.43E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11445 15370541c0abe9d13d081fb4c0218da9 770 SUPERFAMILY SSF52540 223 301 6.43E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11445 15370541c0abe9d13d081fb4c0218da9 770 SUPERFAMILY SSF52540 384 441 6.43E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11445 15370541c0abe9d13d081fb4c0218da9 770 Gene3D G3DSA:3.40.50.300 433 590 3.9E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11445 15370541c0abe9d13d081fb4c0218da9 770 Gene3D G3DSA:3.40.50.300 229 297 3.9E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08230 25c6c9a0a908e4fdbc571c9c054b766d 341 SUPERFAMILY SSF52540 6 234 4.05E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08230 25c6c9a0a908e4fdbc571c9c054b766d 341 Pfam PF13732 Domain of unknown function (DUF4162) 227 319 3.4E-7 T 06-07-2017 IPR025302 Domain of unknown function DUF4162 LK06_RS08230 25c6c9a0a908e4fdbc571c9c054b766d 341 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS08230 25c6c9a0a908e4fdbc571c9c054b766d 341 Gene3D G3DSA:3.40.50.300 12 237 1.0E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08230 25c6c9a0a908e4fdbc571c9c054b766d 341 Pfam PF00005 ABC transporter 30 173 6.4E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS08230 25c6c9a0a908e4fdbc571c9c054b766d 341 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 22 321 4.3E-122 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 LK06_RS08230 25c6c9a0a908e4fdbc571c9c054b766d 341 SMART SM00382 39 222 7.2E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS14060 c3e451562e275fde94a44d19c88db270 365 Gene3D G3DSA:3.40.50.300 129 337 4.4E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14060 c3e451562e275fde94a44d19c88db270 365 SUPERFAMILY SSF52540 130 330 1.43E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14060 c3e451562e275fde94a44d19c88db270 365 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 133 288 1.5E-10 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain LK06_RS14060 c3e451562e275fde94a44d19c88db270 365 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 20 352 1.0E-102 T 06-07-2017 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like LK06_RS00365 cfad054f96a5c4ee49813bbdbca18507 304 ProSitePatterns PS01125 ROK family signature. 134 161 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS00365 cfad054f96a5c4ee49813bbdbca18507 304 Gene3D G3DSA:3.30.420.40 139 280 9.7E-42 T 06-07-2017 LK06_RS00365 cfad054f96a5c4ee49813bbdbca18507 304 Pfam PF00480 ROK family 3 296 5.2E-56 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS00365 cfad054f96a5c4ee49813bbdbca18507 304 Gene3D G3DSA:3.30.420.40 2 138 2.3E-37 T 06-07-2017 LK06_RS00365 cfad054f96a5c4ee49813bbdbca18507 304 SUPERFAMILY SSF53067 2 296 1.06E-58 T 06-07-2017 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 Pfam PF00009 Elongation factor Tu GTP binding domain 9 214 3.3E-52 T 06-07-2017 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 SUPERFAMILY SSF50447 165 187 1.85E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 SUPERFAMILY SSF50447 214 318 1.85E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 Pfam PF00679 Elongation factor G C-terminus 428 509 3.0E-20 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 155 1.9E-21 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 Pfam PF03144 Elongation factor Tu domain 2 238 308 4.1E-10 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 Gene3D G3DSA:3.40.50.300 6 224 2.5E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 10 630 1.3E-288 T 06-07-2017 IPR006298 GTP-binding protein TypA GO:0005525 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 Gene3D G3DSA:2.40.30.10 225 322 5.8E-29 T 06-07-2017 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 SUPERFAMILY SSF54980 323 419 2.09E-9 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 Gene3D G3DSA:3.30.70.870 323 433 1.2E-33 T 06-07-2017 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 Gene3D G3DSA:3.30.70.240 434 512 7.1E-30 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 Gene3D G3DSA:2.40.50.250 514 608 3.1E-39 T 06-07-2017 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 SUPERFAMILY SSF52540 7 224 4.28E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 SMART SM00838 427 515 0.01 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 PRINTS PR00315 GTP-binding elongation factor signature 136 145 4.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 PRINTS PR00315 GTP-binding elongation factor signature 100 111 4.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 PRINTS PR00315 GTP-binding elongation factor signature 84 94 4.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS21815 56bfc878a7412d1254545a555f9f9de1 638 SUPERFAMILY SSF54980 430 544 3.98E-27 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 194 301 1.0E-55 T 06-07-2017 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 SUPERFAMILY SSF55620 11 147 1.51E-41 T 06-07-2017 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 PRINTS PR00093 Uricase signature 19 30 1.7E-17 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 PRINTS PR00093 Uricase signature 164 180 1.7E-17 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 PRINTS PR00093 Uricase signature 58 72 1.7E-17 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 PRINTS PR00093 Uricase signature 94 107 1.7E-17 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 PRINTS PR00093 Uricase signature 180 192 1.7E-17 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 TIGRFAM TIGR03383 urate_oxi: urate oxidase 13 301 5.3E-110 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 Gene3D G3DSA:3.10.270.10 11 306 1.2E-113 T 06-07-2017 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 Pfam PF01014 Uricase 17 149 1.9E-18 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 Pfam PF01014 Uricase 159 296 6.8E-34 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 SUPERFAMILY SSF55620 155 305 1.11E-57 T 06-07-2017 LK06_RS27405 02b539f3b01e3957c62defa969f9e7da 315 PIRSF PIRSF000241 1 308 6.0E-112 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 Pfam PF00106 short chain dehydrogenase 3 188 2.3E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 8.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 8.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 8.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 8.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 8.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 SUPERFAMILY SSF51735 3 231 7.83E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 PIRSF PIRSF000126 1 251 4.7E-66 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 179 0.0022 T 06-07-2017 LK06_RS20130 0c45927b5b87e42c31e05d6e2d1bc0f3 257 Gene3D G3DSA:3.40.50.720 3 217 4.9E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS17680 3ac1bf2c2d9ef72868e6819c6915bafa 145 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 6 144 1.5E-49 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 LK06_RS17680 3ac1bf2c2d9ef72868e6819c6915bafa 145 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 5 145 30.758 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 LK06_RS17680 3ac1bf2c2d9ef72868e6819c6915bafa 145 Gene3D G3DSA:3.50.80.10 5 144 5.7E-53 T 06-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain LK06_RS17680 3ac1bf2c2d9ef72868e6819c6915bafa 145 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 5 144 1.0E-40 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 LK06_RS17680 3ac1bf2c2d9ef72868e6819c6915bafa 145 SUPERFAMILY SSF69500 5 144 7.98E-46 T 06-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain LK06_RS11095 11fd2e69367e006b3e492a74b5266774 420 Pfam PF04286 Protein of unknown function (DUF445) 55 415 1.4E-99 T 06-07-2017 IPR007383 Protein of unknown function DUF445 LK06_RS05150 6b2c7ab01f6f214a1eed0540771bfe3d 331 SUPERFAMILY SSF144083 266 328 8.63E-19 T 06-07-2017 LK06_RS05150 6b2c7ab01f6f214a1eed0540771bfe3d 331 SUPERFAMILY SSF143865 2 264 2.22E-63 T 06-07-2017 LK06_RS05150 6b2c7ab01f6f214a1eed0540771bfe3d 331 Gene3D G3DSA:3.30.460.20 2 132 1.7E-41 T 06-07-2017 LK06_RS05150 6b2c7ab01f6f214a1eed0540771bfe3d 331 Pfam PF01544 CorA-like Mg2+ transporter protein 32 326 3.5E-60 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 LK06_RS05150 6b2c7ab01f6f214a1eed0540771bfe3d 331 Gene3D G3DSA:1.20.58.340 133 253 2.0E-35 T 06-07-2017 LK06_RS05150 6b2c7ab01f6f214a1eed0540771bfe3d 331 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 33 331 2.4E-61 T 06-07-2017 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 LK06_RS05150 6b2c7ab01f6f214a1eed0540771bfe3d 331 Gene3D G3DSA:1.20.58.340 255 331 2.8E-26 T 06-07-2017 LK06_RS01225 6ab0bc335d1e8a1ee27fc66c4c488bae 343 SUPERFAMILY SSF51735 6 327 1.36E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01225 6ab0bc335d1e8a1ee27fc66c4c488bae 343 Gene3D G3DSA:3.90.25.10 226 324 8.7E-6 T 06-07-2017 LK06_RS01225 6ab0bc335d1e8a1ee27fc66c4c488bae 343 Gene3D G3DSA:3.40.50.720 3 225 1.9E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01225 6ab0bc335d1e8a1ee27fc66c4c488bae 343 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 177 1.0E-17 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 Pfam PF02018 Carbohydrate binding domain 42 156 1.3E-15 T 06-07-2017 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 SMART SM00636 286 557 1.2E-7 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 ProSitePatterns PS01095 Chitinases family 18 active site. 394 402 - T 06-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 Gene3D G3DSA:2.60.120.260 42 173 4.8E-11 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 SMART SM00060 186 256 1.3E-13 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 Pfam PF00704 Glycosyl hydrolases family 18 288 557 2.5E-30 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 SUPERFAMILY SSF49265 183 269 7.77E-20 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 SUPERFAMILY SSF51445 283 563 6.22E-58 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 Gene3D G3DSA:2.60.40.10 184 264 6.5E-22 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 Gene3D G3DSA:3.20.20.80 285 564 1.5E-63 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 Pfam PF00041 Fibronectin type III domain 187 259 1.0E-8 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 LK06_RS21245 0c88eae3f1160bd1aed546130606d866 576 SUPERFAMILY SSF49785 40 174 7.48E-13 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS25060 598e753f6a9fa317bf01f92d34658a7d 311 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 63 161 5.2E-15 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 LK06_RS25060 598e753f6a9fa317bf01f92d34658a7d 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 269 8.0E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS25060 598e753f6a9fa317bf01f92d34658a7d 311 Gene3D G3DSA:1.10.3720.10 60 269 1.6E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS25060 598e753f6a9fa317bf01f92d34658a7d 311 SUPERFAMILY SSF161098 62 268 1.74E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26855 8008569662dba17b1d86ec06e923fef1 416 SUPERFAMILY SSF53187 8 191 6.29E-22 T 06-07-2017 LK06_RS26855 8008569662dba17b1d86ec06e923fef1 416 SMART SM00631 9 244 0.0063 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 LK06_RS26855 8008569662dba17b1d86ec06e923fef1 416 Gene3D G3DSA:3.40.630.10 13 188 1.4E-14 T 06-07-2017 LK06_RS26855 8008569662dba17b1d86ec06e923fef1 416 Pfam PF00246 Zinc carboxypeptidase 17 175 1.5E-11 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 Gene3D G3DSA:3.40.50.300 319 528 2.9E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 SMART SM00382 30 233 3.9E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 SMART SM00382 346 516 1.1E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 SUPERFAMILY SSF52540 304 507 1.22E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 551 1.9E-274 T 06-07-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 Pfam PF12848 ABC transporter 227 301 1.5E-12 T 06-07-2017 IPR032781 ABC-transporter extension domain LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 Pfam PF00005 ABC transporter 338 471 5.0E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 Pfam PF00005 ABC transporter 21 188 1.4E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 SUPERFAMILY SSF52540 11 241 5.98E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 Gene3D G3DSA:3.40.50.300 8 105 4.4E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10195 1629ca73c77e9772e4eeb1e4c29615fe 554 Gene3D G3DSA:3.40.50.300 138 285 4.4E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20845 c8daddeb49a727c36aee4e5a1cea82b3 205 PIRSF PIRSF006305 1 198 1.1E-43 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 LK06_RS20845 c8daddeb49a727c36aee4e5a1cea82b3 205 Gene3D G3DSA:3.90.950.10 7 195 3.0E-60 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like LK06_RS20845 c8daddeb49a727c36aee4e5a1cea82b3 205 SUPERFAMILY SSF52972 7 192 1.77E-53 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like LK06_RS20845 c8daddeb49a727c36aee4e5a1cea82b3 205 Pfam PF02545 Maf-like protein 8 192 5.8E-46 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 LK06_RS20845 c8daddeb49a727c36aee4e5a1cea82b3 205 Hamap MF_00528 Septum formation protein Maf [maf]. 8 197 28.012 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 LK06_RS20845 c8daddeb49a727c36aee4e5a1cea82b3 205 TIGRFAM TIGR00172 maf: septum formation protein Maf 8 190 7.4E-45 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 LK06_RS01255 1d3cc2e0a7332239bec33ca1ea9691b8 241 Pfam PF10615 Protein of unknown function (DUF2470) 142 216 5.3E-8 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 LK06_RS01255 1d3cc2e0a7332239bec33ca1ea9691b8 241 SUPERFAMILY SSF50475 67 224 1.61E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS01255 1d3cc2e0a7332239bec33ca1ea9691b8 241 Gene3D G3DSA:3.20.180.10 135 226 1.3E-7 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 LK06_RS27845 1e1307be60287a43ac667afb2688ea32 427 Gene3D G3DSA:3.90.1150.10 309 424 1.2E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS27845 1e1307be60287a43ac667afb2688ea32 427 Pfam PF00202 Aminotransferase class-III 24 423 3.5E-82 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS27845 1e1307be60287a43ac667afb2688ea32 427 SUPERFAMILY SSF53383 14 423 7.01E-102 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS27845 1e1307be60287a43ac667afb2688ea32 427 Gene3D G3DSA:3.40.640.10 59 308 1.6E-65 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS12995 22aaea5d001c3592303931165136ea5b 261 Pfam PF01478 Type IV leader peptidase family 115 225 7.1E-18 T 06-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 LK06_RS12995 22aaea5d001c3592303931165136ea5b 261 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 180 190 3.8E-7 T 06-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial LK06_RS12995 22aaea5d001c3592303931165136ea5b 261 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 191 202 3.8E-7 T 06-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial LK06_RS12995 22aaea5d001c3592303931165136ea5b 261 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 123 140 3.8E-7 T 06-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial LK06_RS25310 d05edcf693821fbc8b1444635d0557a7 385 SMART SM00387 295 385 0.0054 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25310 d05edcf693821fbc8b1444635d0557a7 385 Pfam PF07730 Histidine kinase 196 262 7.7E-14 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS25310 d05edcf693821fbc8b1444635d0557a7 385 Gene3D G3DSA:3.30.565.10 289 384 2.9E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25310 d05edcf693821fbc8b1444635d0557a7 385 SUPERFAMILY SSF55874 283 384 1.05E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11190 eb537d0641c937ecde6ddcf27bba1b71 250 SUPERFAMILY SSF56281 1 250 1.06E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS11190 eb537d0641c937ecde6ddcf27bba1b71 250 SMART SM00849 18 217 0.0088 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS11190 eb537d0641c937ecde6ddcf27bba1b71 250 Pfam PF12706 Beta-lactamase superfamily domain 30 218 2.5E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS11190 eb537d0641c937ecde6ddcf27bba1b71 250 Gene3D G3DSA:3.60.15.10 1 249 8.5E-59 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS02720 ceaa1cc1b5b1f6dad8e9dfd014d7b2af 494 SUPERFAMILY SSF55103 191 466 2.29E-59 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LK06_RS02720 ceaa1cc1b5b1f6dad8e9dfd014d7b2af 494 Pfam PF02913 FAD linked oxidases, C-terminal domain 218 463 2.8E-65 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LK06_RS02720 ceaa1cc1b5b1f6dad8e9dfd014d7b2af 494 Gene3D G3DSA:3.30.43.10 2 95 1.7E-24 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS02720 ceaa1cc1b5b1f6dad8e9dfd014d7b2af 494 Pfam PF01565 FAD binding domain 40 179 4.6E-44 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LK06_RS02720 ceaa1cc1b5b1f6dad8e9dfd014d7b2af 494 SUPERFAMILY SSF56176 2 214 7.94E-74 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS02720 ceaa1cc1b5b1f6dad8e9dfd014d7b2af 494 Gene3D G3DSA:1.10.45.10 424 464 9.9E-17 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 LK06_RS02720 ceaa1cc1b5b1f6dad8e9dfd014d7b2af 494 Gene3D G3DSA:3.30.465.10 96 215 1.6E-46 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS21235 271ca5cc9cf29c302727c6c331e3bb35 283 Pfam PF13560 Helix-turn-helix domain 13 70 1.2E-11 T 06-07-2017 LK06_RS21235 271ca5cc9cf29c302727c6c331e3bb35 283 Gene3D G3DSA:1.10.260.40 6 73 5.3E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS21235 271ca5cc9cf29c302727c6c331e3bb35 283 SMART SM00530 17 72 1.2E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS21235 271ca5cc9cf29c302727c6c331e3bb35 283 SUPERFAMILY SSF47413 9 73 2.25E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS03915 3c3e779ce118106bc11ce2c1c51ee4e5 362 Pfam PF00571 CBS domain 282 331 9.4E-5 T 06-07-2017 IPR000644 CBS domain LK06_RS03915 3c3e779ce118106bc11ce2c1c51ee4e5 362 Pfam PF00571 CBS domain 220 268 1.8E-4 T 06-07-2017 IPR000644 CBS domain LK06_RS03915 3c3e779ce118106bc11ce2c1c51ee4e5 362 SUPERFAMILY SSF54631 203 340 2.15E-23 T 06-07-2017 LK06_RS03915 3c3e779ce118106bc11ce2c1c51ee4e5 362 SMART SM00116 222 271 0.26 T 06-07-2017 IPR000644 CBS domain LK06_RS03915 3c3e779ce118106bc11ce2c1c51ee4e5 362 SMART SM00116 283 331 1.3 T 06-07-2017 IPR000644 CBS domain LK06_RS03915 3c3e779ce118106bc11ce2c1c51ee4e5 362 Gene3D G3DSA:3.10.580.10 220 331 1.8E-16 T 06-07-2017 LK06_RS03915 3c3e779ce118106bc11ce2c1c51ee4e5 362 Pfam PF01595 Domain of unknown function DUF21 8 198 1.4E-38 T 06-07-2017 IPR002550 Domain of unknown function DUF21 LK06_RS30215 5f9512535c1db8c62ff3a94ef2af19f8 241 Gene3D G3DSA:3.20.20.70 2 149 6.7E-38 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS30215 5f9512535c1db8c62ff3a94ef2af19f8 241 PIRSF PIRSF036990 4 230 2.2E-64 T 06-07-2017 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON LK06_RS30215 5f9512535c1db8c62ff3a94ef2af19f8 241 SMART SM00116 13 61 2.0E-8 T 06-07-2017 IPR000644 CBS domain LK06_RS30215 5f9512535c1db8c62ff3a94ef2af19f8 241 SMART SM00116 99 147 9.4E-17 T 06-07-2017 IPR000644 CBS domain LK06_RS30215 5f9512535c1db8c62ff3a94ef2af19f8 241 Pfam PF00571 CBS domain 6 58 8.8E-14 T 06-07-2017 IPR000644 CBS domain LK06_RS30215 5f9512535c1db8c62ff3a94ef2af19f8 241 Pfam PF00571 CBS domain 93 146 3.9E-17 T 06-07-2017 IPR000644 CBS domain LK06_RS30215 5f9512535c1db8c62ff3a94ef2af19f8 241 Pfam PF04972 BON domain 149 217 7.5E-12 T 06-07-2017 IPR007055 BON domain LK06_RS30215 5f9512535c1db8c62ff3a94ef2af19f8 241 SUPERFAMILY SSF54631 2 152 7.33E-39 T 06-07-2017 LK06_RS02885 7e58029a635d8f30bf8c9ef36c6f8a28 563 Pfam PF05960 Bacterial protein of unknown function (DUF885) 25 558 1.4E-149 T 06-07-2017 IPR010281 Protein of unknown function DUF885 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 Gene3D G3DSA:1.10.520.10 437 592 4.9E-65 T 06-07-2017 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 Gene3D G3DSA:1.10.520.10 55 209 2.1E-73 T 06-07-2017 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 Gene3D G3DSA:1.10.520.10 718 739 4.9E-65 T 06-07-2017 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 Gene3D G3DSA:1.10.520.10 242 254 2.1E-73 T 06-07-2017 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 262 272 - T 06-07-2017 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 SUPERFAMILY SSF48113 27 435 2.36E-157 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 Gene3D G3DSA:1.10.420.10 593 715 2.7E-44 T 06-07-2017 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 Gene3D G3DSA:1.10.420.10 255 277 2.2E-47 T 06-07-2017 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 Gene3D G3DSA:1.10.420.10 313 412 2.2E-47 T 06-07-2017 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 Hamap MF_01961 Catalase-peroxidase [katG]. 13 740 42.566 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 Pfam PF00141 Peroxidase 92 400 8.8E-48 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 Pfam PF00141 Peroxidase 407 713 4.1E-37 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 PRINTS PR00458 Haem peroxidase superfamily signature 262 277 1.3E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 PRINTS PR00458 Haem peroxidase superfamily signature 158 175 1.3E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 PRINTS PR00458 Haem peroxidase superfamily signature 176 188 1.3E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 PRINTS PR00458 Haem peroxidase superfamily signature 321 336 1.3E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 PRINTS PR00458 Haem peroxidase superfamily signature 98 112 1.3E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 ProSitePatterns PS00436 Peroxidases active site signature. 98 109 - T 06-07-2017 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 SUPERFAMILY SSF48113 435 739 6.04E-111 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 75 100 1.7E-51 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 270 293 1.7E-51 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 60 73 1.7E-51 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 34 56 1.7E-51 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 485 511 1.7E-51 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 LK06_RS00600 92a17f27a77106cbb8b4ae54457f9762 740 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 31 740 0.0 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 LK06_RS25440 699e37a1548a6945c0ea1e5ba50982cd 375 Hamap MF_00323 Ferrochelatase [hemH]. 9 330 30.008 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 LK06_RS25440 699e37a1548a6945c0ea1e5ba50982cd 375 Pfam PF00762 Ferrochelatase 11 329 1.8E-90 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 LK06_RS25440 699e37a1548a6945c0ea1e5ba50982cd 375 Gene3D G3DSA:3.40.50.1400 8 164 3.7E-39 T 06-07-2017 LK06_RS25440 699e37a1548a6945c0ea1e5ba50982cd 375 Gene3D G3DSA:3.40.50.1400 165 309 3.3E-44 T 06-07-2017 LK06_RS25440 699e37a1548a6945c0ea1e5ba50982cd 375 SUPERFAMILY SSF53800 9 335 9.81E-81 T 06-07-2017 LK06_RS16700 7cf1dd593b875477c64d134c839663c2 175 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 2 173 6.9E-30 T 06-07-2017 IPR023869 tRNA adenosine deaminase-associated protein, putative LK06_RS07820 71c67f08a06f1a0ecd2ce3c0f2997a5e 173 Pfam PF14024 Protein of unknown function (DUF4240) 2 129 1.6E-45 T 06-07-2017 IPR025334 Domain of unknown function (DUF4240 LK06_RS05470 41ac229df482f880c49d70892b92f375 471 Gene3D G3DSA:3.20.20.80 106 375 5.9E-38 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS05470 41ac229df482f880c49d70892b92f375 471 Pfam PF01229 Glycosyl hydrolases family 39 120 244 1.6E-7 T 06-07-2017 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 LK06_RS05470 41ac229df482f880c49d70892b92f375 471 SUPERFAMILY SSF51445 106 384 2.21E-34 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS23855 e61845fcc5e2f793aa649c0730c91d70 107 Pfam PF04248 Domain of unknown function (DUF427) 16 103 5.3E-32 T 06-07-2017 IPR007361 Domain of unknown function DUF427 LK06_RS02880 ca095a6cebc86b7e8da00896967c7f2a 161 Gene3D G3DSA:3.30.70.920 59 148 4.7E-21 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS02880 ca095a6cebc86b7e8da00896967c7f2a 161 SMART SM00344 7 116 4.1E-33 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS02880 ca095a6cebc86b7e8da00896967c7f2a 161 Gene3D G3DSA:1.10.10.10 6 55 1.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02880 ca095a6cebc86b7e8da00896967c7f2a 161 SUPERFAMILY SSF46785 6 66 1.73E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02880 ca095a6cebc86b7e8da00896967c7f2a 161 SUPERFAMILY SSF54909 69 153 2.28E-14 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS02880 ca095a6cebc86b7e8da00896967c7f2a 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.1E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS02880 ca095a6cebc86b7e8da00896967c7f2a 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.1E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS02880 ca095a6cebc86b7e8da00896967c7f2a 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.1E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS02880 ca095a6cebc86b7e8da00896967c7f2a 161 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 1.2E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS02880 ca095a6cebc86b7e8da00896967c7f2a 161 Pfam PF01037 Lrp/AsnC ligand binding domain 75 146 2.8E-16 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 453 470 6.5E-20 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 401 417 6.5E-20 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 252 266 6.5E-20 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 285 295 6.5E-20 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 351 363 6.5E-20 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 SUPERFAMILY SSF53335 168 470 1.88E-52 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 Gene3D G3DSA:3.40.50.150 262 470 8.7E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 Gene3D G3DSA:1.10.940.10 20 182 3.3E-47 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 Pfam PF01029 NusB family 23 148 9.6E-26 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 SUPERFAMILY SSF48013 23 180 3.79E-35 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 350 361 - T 06-07-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS04055 9fb730286fb0c908be4019639e22f848 472 Pfam PF01189 16S rRNA methyltransferase RsmB/F 281 468 1.0E-46 T 06-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS31750 1b3fd8e68dc44be22393df5ccc6ab7b5 468 Gene3D G3DSA:3.40.50.980 33 156 9.4E-10 T 06-07-2017 LK06_RS31750 1b3fd8e68dc44be22393df5ccc6ab7b5 468 Pfam PF00501 AMP-binding enzyme 35 377 3.5E-31 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS31750 1b3fd8e68dc44be22393df5ccc6ab7b5 468 SUPERFAMILY SSF56801 16 456 4.45E-71 T 06-07-2017 LK06_RS31750 1b3fd8e68dc44be22393df5ccc6ab7b5 468 Pfam PF13193 AMP-binding enzyme C-terminal domain 386 453 2.6E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS31750 1b3fd8e68dc44be22393df5ccc6ab7b5 468 Gene3D G3DSA:3.40.50.980 157 302 2.4E-22 T 06-07-2017 LK06_RS31750 1b3fd8e68dc44be22393df5ccc6ab7b5 468 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS31750 1b3fd8e68dc44be22393df5ccc6ab7b5 468 Gene3D G3DSA:3.30.300.30 372 457 4.9E-15 T 06-07-2017 LK06_RS32385 239c7762b18cf9dc18db9ebac6214e0c 1277 Gene3D G3DSA:3.40.50.300 517 741 3.5E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32385 239c7762b18cf9dc18db9ebac6214e0c 1277 Pfam PF03796 DnaB-like helicase C terminal domain 518 684 3.4E-16 T 06-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 LK06_RS32385 239c7762b18cf9dc18db9ebac6214e0c 1277 SUPERFAMILY SSF52540 513 602 1.67E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32385 239c7762b18cf9dc18db9ebac6214e0c 1277 SUPERFAMILY SSF52540 638 689 1.67E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05780 43f3921b5ad5e353b52e66cb3bbbd3b6 267 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS05780 43f3921b5ad5e353b52e66cb3bbbd3b6 267 SMART SM00382 28 217 2.0E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS05780 43f3921b5ad5e353b52e66cb3bbbd3b6 267 Gene3D G3DSA:3.40.50.300 3 236 2.7E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05780 43f3921b5ad5e353b52e66cb3bbbd3b6 267 Pfam PF00005 ABC transporter 21 167 1.3E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS05780 43f3921b5ad5e353b52e66cb3bbbd3b6 267 SUPERFAMILY SSF52540 4 229 3.59E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19385 ae520f20a0141b06e1b39a9da68c138f 166 Gene3D G3DSA:3.40.980.10 3 154 3.0E-49 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS19385 ae520f20a0141b06e1b39a9da68c138f 166 SMART SM00852 6 148 5.3E-21 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS19385 ae520f20a0141b06e1b39a9da68c138f 166 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 140 2.5E-30 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS19385 ae520f20a0141b06e1b39a9da68c138f 166 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 64 77 - T 06-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 LK06_RS19385 ae520f20a0141b06e1b39a9da68c138f 166 SUPERFAMILY SSF53218 2 153 2.62E-40 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS19385 ae520f20a0141b06e1b39a9da68c138f 166 Pfam PF00994 Probable molybdopterin binding domain 7 145 1.3E-27 T 06-07-2017 IPR001453 MoaB/Mog domain LK06_RS13460 4bbd3863ecb0af10801342eb9182e542 353 Gene3D G3DSA:3.40.50.720 3 213 2.8E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13460 4bbd3863ecb0af10801342eb9182e542 353 SUPERFAMILY SSF51735 2 316 6.15E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13460 4bbd3863ecb0af10801342eb9182e542 353 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 236 5.2E-21 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS28730 701f4dd53e07ac0f3de4457166caf0ad 475 Pfam PF01593 Flavin containing amine oxidoreductase 29 456 4.9E-44 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 LK06_RS28730 701f4dd53e07ac0f3de4457166caf0ad 475 SUPERFAMILY SSF51905 19 329 1.42E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS28730 701f4dd53e07ac0f3de4457166caf0ad 475 SUPERFAMILY SSF51905 417 460 1.42E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS28730 701f4dd53e07ac0f3de4457166caf0ad 475 Gene3D G3DSA:3.50.50.60 22 109 1.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS28730 701f4dd53e07ac0f3de4457166caf0ad 475 Gene3D G3DSA:3.50.50.60 241 296 1.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS28730 701f4dd53e07ac0f3de4457166caf0ad 475 Gene3D G3DSA:3.50.50.60 395 457 1.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS28730 701f4dd53e07ac0f3de4457166caf0ad 475 Gene3D G3DSA:3.50.50.60 171 187 1.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS28730 701f4dd53e07ac0f3de4457166caf0ad 475 PRINTS PR00757 Flavin-containing amine oxidase signature 438 455 8.9E-5 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 LK06_RS28730 701f4dd53e07ac0f3de4457166caf0ad 475 PRINTS PR00757 Flavin-containing amine oxidase signature 21 40 8.9E-5 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 LK06_RS28730 701f4dd53e07ac0f3de4457166caf0ad 475 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 23 457 2.6E-139 T 06-07-2017 IPR017830 Squalene-associated FAD-dependent desaturase LK06_RS27165 73d96a52489beec0114b5773e3a20753 369 Gene3D G3DSA:3.40.50.1820 54 215 6.0E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27165 73d96a52489beec0114b5773e3a20753 369 Gene3D G3DSA:3.40.50.1820 267 362 6.0E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27165 73d96a52489beec0114b5773e3a20753 369 Pfam PF00756 Putative esterase 78 358 2.7E-29 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 LK06_RS27165 73d96a52489beec0114b5773e3a20753 369 SUPERFAMILY SSF53474 61 212 4.36E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27165 73d96a52489beec0114b5773e3a20753 369 SUPERFAMILY SSF53474 269 336 4.36E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS11795 df4d1314205aeedf4964d727d990dc17 329 PIRSF PIRSF002849 2 329 3.6E-133 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted LK06_RS11795 df4d1314205aeedf4964d727d990dc17 329 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 51 181 2.5E-64 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 LK06_RS11795 df4d1314205aeedf4964d727d990dc17 329 Gene3D G3DSA:3.40.50.300 33 197 8.4E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11795 df4d1314205aeedf4964d727d990dc17 329 SMART SM00382 48 189 2.7E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS11795 df4d1314205aeedf4964d727d990dc17 329 SUPERFAMILY SSF52540 20 304 1.91E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11795 df4d1314205aeedf4964d727d990dc17 329 Gene3D G3DSA:1.10.8.300 219 325 4.9E-38 T 06-07-2017 LK06_RS19155 e6ac5f87019dc240350e742969d8c426 251 SUPERFAMILY SSF52172 4 127 3.98E-39 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS19155 e6ac5f87019dc240350e742969d8c426 251 SMART SM00448 3 113 6.1E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS19155 e6ac5f87019dc240350e742969d8c426 251 Pfam PF00072 Response regulator receiver domain 5 114 2.8E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS19155 e6ac5f87019dc240350e742969d8c426 251 SUPERFAMILY SSF46894 131 231 1.05E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS19155 e6ac5f87019dc240350e742969d8c426 251 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 230 2.6E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS19155 e6ac5f87019dc240350e742969d8c426 251 Gene3D G3DSA:3.40.50.2300 3 125 1.1E-38 T 06-07-2017 LK06_RS19155 e6ac5f87019dc240350e742969d8c426 251 Gene3D G3DSA:1.10.10.10 131 231 2.4E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19155 e6ac5f87019dc240350e742969d8c426 251 SMART SM00862 154 230 1.1E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS25005 a363f0dc1fbbfea9db449128f4141e3e 156 SUPERFAMILY SSF47240 2 153 4.51E-46 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS25005 a363f0dc1fbbfea9db449128f4141e3e 156 PIRSF PIRSF005900 1 156 1.2E-42 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 LK06_RS25005 a363f0dc1fbbfea9db449128f4141e3e 156 Gene3D G3DSA:1.20.1260.10 3 153 4.4E-44 T 06-07-2017 IPR012347 Ferritin-related LK06_RS25005 a363f0dc1fbbfea9db449128f4141e3e 156 Pfam PF00210 Ferritin-like domain 18 153 1.1E-20 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 LK06_RS25005 a363f0dc1fbbfea9db449128f4141e3e 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 4.0E-12 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 LK06_RS25005 a363f0dc1fbbfea9db449128f4141e3e 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 4.0E-12 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 LK06_RS25005 a363f0dc1fbbfea9db449128f4141e3e 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 4.0E-12 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 LK06_RS01220 af3e5021cb0918c34d678180ba07a912 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 3.3E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS01220 af3e5021cb0918c34d678180ba07a912 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 219 233 3.3E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS01220 af3e5021cb0918c34d678180ba07a912 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 3.3E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS01220 af3e5021cb0918c34d678180ba07a912 294 Pfam PF12697 Alpha/beta hydrolase family 28 266 6.8E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS01220 af3e5021cb0918c34d678180ba07a912 294 SUPERFAMILY SSF53474 7 275 9.21E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS01220 af3e5021cb0918c34d678180ba07a912 294 Gene3D G3DSA:3.40.50.1820 8 274 5.2E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS17445 df64accf40b64cbdb37c289aa08dfd7f 529 Gene3D G3DSA:3.90.100.10 449 495 9.5E-8 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 LK06_RS17445 df64accf40b64cbdb37c289aa08dfd7f 529 Gene3D G3DSA:3.40.640.10 28 330 1.7E-61 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS17445 df64accf40b64cbdb37c289aa08dfd7f 529 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 28 351 9.4E-53 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 LK06_RS17445 df64accf40b64cbdb37c289aa08dfd7f 529 SUPERFAMILY SSF53383 28 438 3.39E-45 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS06345 c8918a110d3df6d96319c1992ff55b39 353 Pfam PF00266 Aminotransferase class-V 56 347 5.9E-18 T 06-07-2017 IPR000192 Aminotransferase class V domain LK06_RS06345 c8918a110d3df6d96319c1992ff55b39 353 Gene3D G3DSA:3.40.640.10 55 261 2.8E-30 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS06345 c8918a110d3df6d96319c1992ff55b39 353 SUPERFAMILY SSF53383 11 352 1.3E-48 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS06345 c8918a110d3df6d96319c1992ff55b39 353 Gene3D G3DSA:3.90.1150.10 262 352 2.0E-6 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 SUPERFAMILY SSF158472 79 127 1.57E-10 T 06-07-2017 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 255 367 8.9E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 Pfam PF00512 His Kinase A (phospho-acceptor) domain 132 195 4.4E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 SMART SM00304 78 130 1.7E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 367 1.8E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 307 1.8E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 349 1.8E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 Gene3D G3DSA:1.10.287.130 121 181 1.6E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 SMART SM00388 131 195 6.3E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 SUPERFAMILY SSF55874 185 367 2.49E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 Gene3D G3DSA:3.30.565.10 247 367 1.3E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 Gene3D G3DSA:3.30.565.10 182 214 1.3E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 Pfam PF00672 HAMP domain 61 126 6.3E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 SUPERFAMILY SSF47384 115 195 5.89E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS22660 2f66ce9c2c8b78bd2f3cc94e112db943 374 SMART SM00387 254 370 7.1E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS26195 64193f8481224dee7713c7c1b727ede1 417 Gene3D G3DSA:1.20.1250.20 21 211 9.3E-9 T 06-07-2017 LK06_RS26195 64193f8481224dee7713c7c1b727ede1 417 Pfam PF07690 Major Facilitator Superfamily 44 361 7.2E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS26195 64193f8481224dee7713c7c1b727ede1 417 Gene3D G3DSA:1.20.1250.20 225 390 5.0E-13 T 06-07-2017 LK06_RS26195 64193f8481224dee7713c7c1b727ede1 417 SUPERFAMILY SSF103473 13 398 8.24E-34 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS11670 0f07b86884ba8864f7a6e1186ed4b54b 326 Gene3D G3DSA:3.90.25.10 171 218 1.5E-37 T 06-07-2017 LK06_RS11670 0f07b86884ba8864f7a6e1186ed4b54b 326 Gene3D G3DSA:3.90.25.10 251 322 1.5E-37 T 06-07-2017 LK06_RS11670 0f07b86884ba8864f7a6e1186ed4b54b 326 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 175 0.0073 T 06-07-2017 LK06_RS11670 0f07b86884ba8864f7a6e1186ed4b54b 326 Gene3D G3DSA:3.40.50.720 1 170 1.1E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11670 0f07b86884ba8864f7a6e1186ed4b54b 326 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 320 1.6E-99 T 06-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 LK06_RS11670 0f07b86884ba8864f7a6e1186ed4b54b 326 SUPERFAMILY SSF51735 1 317 8.47E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11670 0f07b86884ba8864f7a6e1186ed4b54b 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 249 1.8E-53 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 SUPERFAMILY SSF51905 14 187 1.13E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 SUPERFAMILY SSF51905 276 379 1.13E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 Gene3D G3DSA:3.50.50.60 277 361 9.7E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 Gene3D G3DSA:3.50.50.60 15 192 9.7E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 1.0E-35 T 06-07-2017 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 322 340 1.0E-35 T 06-07-2017 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 1.0E-35 T 06-07-2017 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 356 1.0E-35 T 06-07-2017 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 1.0E-35 T 06-07-2017 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 15 37 1.0E-35 T 06-07-2017 LK06_RS31915 5c912afda71d5f86cd3f03f2036f01cf 547 Pfam PF01494 FAD binding domain 14 355 1.4E-59 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS23150 07b024b3e8beb2854f2f054c03ad2504 331 Gene3D G3DSA:3.40.50.150 105 227 2.9E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS23150 07b024b3e8beb2854f2f054c03ad2504 331 Gene3D G3DSA:3.40.50.150 6 98 1.5E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS23150 07b024b3e8beb2854f2f054c03ad2504 331 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 130 135 - T 06-07-2017 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 LK06_RS23150 07b024b3e8beb2854f2f054c03ad2504 331 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 73 93 1.8E-8 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS23150 07b024b3e8beb2854f2f054c03ad2504 331 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 50 68 1.8E-8 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS23150 07b024b3e8beb2854f2f054c03ad2504 331 SUPERFAMILY SSF53335 15 201 1.2E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS23150 07b024b3e8beb2854f2f054c03ad2504 331 Pfam PF01555 DNA methylase 8 89 5.4E-13 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 LK06_RS26665 e817a0317a6e4c7b6b3e5efc10505126 518 Gene3D G3DSA:3.20.20.150 3 271 1.3E-80 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS26665 e817a0317a6e4c7b6b3e5efc10505126 518 SUPERFAMILY SSF51658 23 220 4.97E-11 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS26665 e817a0317a6e4c7b6b3e5efc10505126 518 Pfam PF05114 Protein of unknown function (DUF692) 6 270 1.1E-77 T 06-07-2017 IPR007801 Uncharacterised protein family UPF0276 LK06_RS18240 5732559f7fdde359e930724b990259c9 309 PIRSF PIRSF000535 1 305 5.8E-82 T 06-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 LK06_RS18240 5732559f7fdde359e930724b990259c9 309 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 302 2.0E-93 T 06-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 LK06_RS18240 5732559f7fdde359e930724b990259c9 309 Pfam PF00294 pfkB family carbohydrate kinase 14 285 2.2E-42 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB LK06_RS18240 5732559f7fdde359e930724b990259c9 309 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 LK06_RS18240 5732559f7fdde359e930724b990259c9 309 SUPERFAMILY SSF53613 2 282 7.64E-62 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS18240 5732559f7fdde359e930724b990259c9 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 LK06_RS18240 5732559f7fdde359e930724b990259c9 309 Gene3D G3DSA:3.40.1190.20 34 304 1.2E-82 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS13775 cd14b7dac46127825d520c97add47a4c 177 SUPERFAMILY SSF54427 5 153 8.6E-42 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS13775 cd14b7dac46127825d520c97add47a4c 177 Pfam PF13474 SnoaL-like domain 11 153 5.4E-30 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain LK06_RS13775 cd14b7dac46127825d520c97add47a4c 177 Gene3D G3DSA:3.10.450.50 4 160 1.0E-56 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS06675 6befbcd78fc3b046d8d7fc9248f9adbc 218 SMART SM00849 32 197 6.3E-29 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS06675 6befbcd78fc3b046d8d7fc9248f9adbc 218 Gene3D G3DSA:3.60.15.10 18 216 5.7E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS06675 6befbcd78fc3b046d8d7fc9248f9adbc 218 Pfam PF00753 Metallo-beta-lactamase superfamily 29 167 9.8E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS06675 6befbcd78fc3b046d8d7fc9248f9adbc 218 SUPERFAMILY SSF56281 21 214 1.3E-42 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS00965 d7b58fb7f04a0dbcb8589973865dc00f 291 Pfam PF07728 AAA domain (dynein-related subfamily) 37 187 4.3E-12 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 LK06_RS00965 d7b58fb7f04a0dbcb8589973865dc00f 291 SMART SM00382 32 202 1.2E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS00965 d7b58fb7f04a0dbcb8589973865dc00f 291 SUPERFAMILY SSF52540 110 251 6.36E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00965 d7b58fb7f04a0dbcb8589973865dc00f 291 SUPERFAMILY SSF52540 30 83 6.36E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00965 d7b58fb7f04a0dbcb8589973865dc00f 291 Gene3D G3DSA:3.40.50.300 31 218 8.6E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10595 ab95688aa17ed57617d589d5afe3ba0a 2308 SUPERFAMILY SSF51294 2049 2192 1.18E-16 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain LK06_RS10595 ab95688aa17ed57617d589d5afe3ba0a 2308 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1818 1898 3.9E-19 T 06-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 LK06_RS10595 ab95688aa17ed57617d589d5afe3ba0a 2308 Pfam PF07591 Pretoxin HINT domain 2064 2191 3.1E-16 T 06-07-2017 LK06_RS10595 ab95688aa17ed57617d589d5afe3ba0a 2308 Pfam PF14412 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH 2202 2291 1.2E-17 T 06-07-2017 IPR032871 AHH domain-containing protein LK06_RS10595 ab95688aa17ed57617d589d5afe3ba0a 2308 Gene3D G3DSA:2.170.16.10 2049 2197 3.2E-21 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain LK06_RS10595 ab95688aa17ed57617d589d5afe3ba0a 2308 SMART SM00306 2047 2149 0.0051 T 06-07-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 LK06_RS25650 9792568ec6182d94f2f85eb5b770c06d 250 Pfam PF00975 Thioesterase domain 21 240 4.5E-42 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS25650 9792568ec6182d94f2f85eb5b770c06d 250 SUPERFAMILY SSF53474 5 239 1.38E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS25650 9792568ec6182d94f2f85eb5b770c06d 250 Gene3D G3DSA:3.40.50.1820 12 239 2.4E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 PRINTS PR00415 Aconitase family signature 343 354 2.3E-46 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 PRINTS PR00415 Aconitase family signature 108 116 2.3E-46 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 PRINTS PR00415 Aconitase family signature 209 222 2.3E-46 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 PRINTS PR00415 Aconitase family signature 119 132 2.3E-46 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 PRINTS PR00415 Aconitase family signature 82 95 2.3E-46 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 PRINTS PR00415 Aconitase family signature 133 148 2.3E-46 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 PRINTS PR00415 Aconitase family signature 399 412 2.3E-46 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 PRINTS PR00415 Aconitase family signature 286 300 2.3E-46 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 PRINTS PR00415 Aconitase family signature 195 208 2.3E-46 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 SUPERFAMILY SSF53732 1 465 1.96E-161 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 8.7E-225 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 58.989 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 3.3E-149 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 Gene3D G3DSA:3.40.1060.10 155 288 4.5E-41 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 Gene3D G3DSA:3.30.499.10 330 466 7.9E-57 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24180 49480adb25336d190062a0a00a103a6b 478 Gene3D G3DSA:3.30.499.10 2 154 3.4E-22 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS29525 4fbf8ff81461e915c8baf2f9c79000ae 335 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 240 8.4E-45 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS29525 4fbf8ff81461e915c8baf2f9c79000ae 335 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 328 1.7E-86 T 06-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 LK06_RS29525 4fbf8ff81461e915c8baf2f9c79000ae 335 Gene3D G3DSA:3.90.25.10 201 329 1.1E-23 T 06-07-2017 LK06_RS29525 4fbf8ff81461e915c8baf2f9c79000ae 335 SUPERFAMILY SSF51735 1 326 6.41E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29525 4fbf8ff81461e915c8baf2f9c79000ae 335 Gene3D G3DSA:3.40.50.720 2 200 1.4E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS19910 eee5a813eb76050a85d59cf187789848 511 Gene3D G3DSA:3.30.200.20 4 81 3.7E-24 T 06-07-2017 LK06_RS19910 eee5a813eb76050a85d59cf187789848 511 SUPERFAMILY SSF48452 367 482 1.21E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS19910 eee5a813eb76050a85d59cf187789848 511 SUPERFAMILY SSF56112 4 294 1.28E-74 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS19910 eee5a813eb76050a85d59cf187789848 511 SMART SM00220 13 275 5.9E-54 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS19910 eee5a813eb76050a85d59cf187789848 511 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS19910 eee5a813eb76050a85d59cf187789848 511 Pfam PF00069 Protein kinase domain 13 269 7.4E-44 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS19910 eee5a813eb76050a85d59cf187789848 511 Gene3D G3DSA:1.25.40.10 338 487 1.1E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS19910 eee5a813eb76050a85d59cf187789848 511 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS19910 eee5a813eb76050a85d59cf187789848 511 Gene3D G3DSA:1.10.510.10 82 272 9.2E-47 T 06-07-2017 LK06_RS13400 f9d5f92fa007303aa1d210cba36c9054 331 Pfam PF13091 PLD-like domain 194 323 7.1E-12 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 LK06_RS13400 f9d5f92fa007303aa1d210cba36c9054 331 Pfam PF13091 PLD-like domain 48 169 9.1E-16 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 LK06_RS13400 f9d5f92fa007303aa1d210cba36c9054 331 Gene3D G3DSA:3.30.870.10 36 172 3.9E-22 T 06-07-2017 LK06_RS13400 f9d5f92fa007303aa1d210cba36c9054 331 Gene3D G3DSA:3.30.870.10 183 325 5.1E-22 T 06-07-2017 LK06_RS13400 f9d5f92fa007303aa1d210cba36c9054 331 SUPERFAMILY SSF56024 172 321 4.49E-20 T 06-07-2017 LK06_RS13400 f9d5f92fa007303aa1d210cba36c9054 331 SUPERFAMILY SSF56024 42 172 1.07E-19 T 06-07-2017 LK06_RS01070 f8955435817b9cd0ded6515f3ed74bda 143 Pfam PF00720 Subtilisin inhibitor-like 39 130 4.1E-37 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 LK06_RS01070 f8955435817b9cd0ded6515f3ed74bda 143 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 102 118 3.1E-27 T 06-07-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 LK06_RS01070 f8955435817b9cd0ded6515f3ed74bda 143 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 119 135 3.1E-27 T 06-07-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 LK06_RS01070 f8955435817b9cd0ded6515f3ed74bda 143 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 40 66 3.1E-27 T 06-07-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 LK06_RS01070 f8955435817b9cd0ded6515f3ed74bda 143 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 66 84 - T 06-07-2017 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 LK06_RS01070 f8955435817b9cd0ded6515f3ed74bda 143 Hamap MF_00778 Probable subtilase-type protease inhibitor [sti]. 38 143 29.814 T 06-07-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 LK06_RS01070 f8955435817b9cd0ded6515f3ed74bda 143 SUPERFAMILY SSF55399 38 140 7.72E-39 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 LK06_RS01070 f8955435817b9cd0ded6515f3ed74bda 143 Gene3D G3DSA:3.30.350.10 39 143 1.1E-34 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 LK06_RS01070 f8955435817b9cd0ded6515f3ed74bda 143 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 46 132 3.0E-35 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 LK06_RS17105 efa523936fcb9b82e63a2c390f4416a5 116 SUPERFAMILY SSF55486 2 115 6.29E-39 T 06-07-2017 LK06_RS17105 efa523936fcb9b82e63a2c390f4416a5 116 Gene3D G3DSA:3.40.390.10 35 108 3.5E-4 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 LK06_RS17105 efa523936fcb9b82e63a2c390f4416a5 116 Pfam PF06262 Zinicin-like metallopeptidase 28 115 4.6E-33 T 06-07-2017 IPR010428 Zinicin-like metallopeptidase LK06_RS07455 a4bb749fac7319c645492dab0812337e 210 Gene3D G3DSA:3.90.420.10 14 199 5.0E-46 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS07455 a4bb749fac7319c645492dab0812337e 210 SUPERFAMILY SSF56524 9 203 7.46E-55 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS07455 a4bb749fac7319c645492dab0812337e 210 Pfam PF00174 Oxidoreductase molybdopterin binding domain 33 181 2.4E-28 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS17285 606fa1f886918d9dad7af12319811ee0 274 SUPERFAMILY SSF53335 46 269 1.58E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS17285 606fa1f886918d9dad7af12319811ee0 274 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 88 269 6.6E-49 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 LK06_RS17285 606fa1f886918d9dad7af12319811ee0 274 Gene3D G3DSA:3.40.50.150 90 225 3.9E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS17285 606fa1f886918d9dad7af12319811ee0 274 Pfam PF02390 Putative methyltransferase 94 263 4.8E-53 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 LK06_RS17285 606fa1f886918d9dad7af12319811ee0 274 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 54 269 29.564 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 7.4E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 7.4E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 253 7.4E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 7.4E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 7.4E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 42 7.4E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 7.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 7.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 7.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 Gene3D G3DSA:3.40.50.720 23 270 4.4E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 24 272 4.2E-101 T 06-07-2017 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 SUPERFAMILY SSF51735 23 271 6.93E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS30155 c820562c3d035d65bfbeb8ecbc38a4ac 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 30 270 8.3E-48 T 06-07-2017 LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 Pfam PF00270 DEAD/DEAH box helicase 34 191 4.2E-16 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 Pfam PF00570 HRDC domain 558 621 7.2E-20 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 SUPERFAMILY SSF52540 16 203 4.24E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 SUPERFAMILY SSF47819 554 624 8.29E-21 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 SMART SM00956 418 524 7.4E-45 T 06-07-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 SUPERFAMILY SSF52540 212 469 3.19E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 Gene3D G3DSA:3.40.50.300 15 207 1.3E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 Gene3D G3DSA:1.10.10.10 350 527 1.5E-54 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 21 474 1.9E-149 T 06-07-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 Pfam PF09382 RQC domain 413 527 3.7E-35 T 06-07-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 Pfam PF00271 Helicase conserved C-terminal domain 229 336 4.4E-15 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 20 622 2.1E-227 T 06-07-2017 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 SMART SM00487 26 222 9.5E-29 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 Gene3D G3DSA:3.40.50.300 211 349 1.6E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 SMART SM00490 255 336 1.0E-23 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 SMART SM00341 552 631 9.0E-9 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 Gene3D G3DSA:1.10.150.80 558 626 5.6E-16 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 LK06_RS12885 9b5a9b4ff026b77f7ab2a4c3b2c9e8e7 670 Pfam PF16124 RecQ zinc-binding 348 411 2.3E-16 T 06-07-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain LK06_RS12005 21cd919c5a518cbaca65869dd6d36f77 372 Gene3D G3DSA:3.20.20.140 36 358 3.5E-88 T 06-07-2017 LK06_RS12005 21cd919c5a518cbaca65869dd6d36f77 372 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 44 343 2.2E-80 T 06-07-2017 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 LK06_RS12005 21cd919c5a518cbaca65869dd6d36f77 372 SUPERFAMILY SSF51556 37 349 1.43E-63 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS14715 ba0c2a440f83d9f656c55e4ef4adcaf4 111 SUPERFAMILY SSF50022 6 87 1.54E-14 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS14715 ba0c2a440f83d9f656c55e4ef4adcaf4 111 Gene3D G3DSA:2.102.10.10 20 61 3.6E-7 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS26135 5fe9269b39f674076408a440baf02515 498 Gene3D G3DSA:3.20.20.300 19 332 6.3E-91 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 LK06_RS26135 5fe9269b39f674076408a440baf02515 498 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 39 329 1.4E-71 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 LK06_RS26135 5fe9269b39f674076408a440baf02515 498 SUPERFAMILY SSF51445 23 333 1.26E-79 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS07170 6668150bec2f2331a135bce4516e9da8 166 Pfam PF04073 Aminoacyl-tRNA editing domain 42 155 9.6E-25 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 LK06_RS07170 6668150bec2f2331a135bce4516e9da8 166 SUPERFAMILY SSF55826 13 163 3.66E-41 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 LK06_RS07170 6668150bec2f2331a135bce4516e9da8 166 Gene3D G3DSA:3.90.960.10 7 164 1.6E-55 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 LK06_RS07170 6668150bec2f2331a135bce4516e9da8 166 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 13 163 2.0E-53 T 06-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC LK06_RS07170 6668150bec2f2331a135bce4516e9da8 166 PIRSF PIRSF006181 8 166 5.4E-51 T 06-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC LK06_RS11985 449a031471478d2133e01d7769cdbf48 385 Gene3D G3DSA:2.40.110.10 128 223 6.3E-42 T 06-07-2017 LK06_RS11985 449a031471478d2133e01d7769cdbf48 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 223 7.8E-28 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS11985 449a031471478d2133e01d7769cdbf48 385 SUPERFAMILY SSF56645 13 247 1.26E-80 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS11985 449a031471478d2133e01d7769cdbf48 385 Gene3D G3DSA:1.20.140.10 224 384 9.8E-72 T 06-07-2017 LK06_RS11985 449a031471478d2133e01d7769cdbf48 385 SUPERFAMILY SSF47203 233 384 1.02E-59 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS11985 449a031471478d2133e01d7769cdbf48 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 124 1.4E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS11985 449a031471478d2133e01d7769cdbf48 385 Gene3D G3DSA:1.10.540.10 14 124 1.1E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS11985 449a031471478d2133e01d7769cdbf48 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS11985 449a031471478d2133e01d7769cdbf48 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS11985 449a031471478d2133e01d7769cdbf48 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 384 3.7E-52 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 Pfam PF13581 Histidine kinase-like ATPase domain 750 857 1.4E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 Pfam PF08448 PAS fold 171 282 3.4E-26 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 SUPERFAMILY SSF55874 776 862 1.62E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 41 160 2.7E-6 T 06-07-2017 IPR000014 PAS domain LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 168 286 1.6E-9 T 06-07-2017 IPR000014 PAS domain LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 SMART SM00091 37 104 0.0048 T 06-07-2017 IPR000014 PAS domain LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 SMART SM00091 164 230 3.5E-6 T 06-07-2017 IPR000014 PAS domain LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 514 737 1.5E-46 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 SUPERFAMILY SSF55785 42 153 8.52E-9 T 06-07-2017 IPR000014 PAS domain LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 SUPERFAMILY SSF55781 292 474 2.75E-13 T 06-07-2017 IPR029016 GAF domain-like LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 SMART SM00065 342 467 4.5E-9 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 Pfam PF01590 GAF domain 387 457 1.1E-5 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 SMART SM00331 488 736 1.4E-42 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 SUPERFAMILY SSF55785 164 278 2.09E-15 T 06-07-2017 IPR000014 PAS domain LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 SUPERFAMILY SSF81606 501 737 8.63E-8 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 Gene3D G3DSA:3.30.450.20 164 280 4.2E-18 T 06-07-2017 LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 Gene3D G3DSA:3.30.450.20 41 153 1.2E-11 T 06-07-2017 LK06_RS21770 37872ea8f7237dae331bb5032a8b7a3e 880 Gene3D G3DSA:3.30.450.40 297 465 6.2E-36 T 06-07-2017 IPR029016 GAF domain-like LK06_RS24780 1ea020a9c93cec37f533b8099fe842b6 302 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 244 301 3.7E-14 T 06-07-2017 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS24780 1ea020a9c93cec37f533b8099fe842b6 302 SUPERFAMILY SSF88697 244 301 5.96E-7 T 06-07-2017 IPR015947 PUA-like domain LK06_RS24780 1ea020a9c93cec37f533b8099fe842b6 302 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 227 6.0E-65 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS24780 1ea020a9c93cec37f533b8099fe842b6 302 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 9 301 16.907 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS24780 1ea020a9c93cec37f533b8099fe842b6 302 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 188 2.0E-47 T 06-07-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 LK06_RS24780 1ea020a9c93cec37f533b8099fe842b6 302 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 189 232 8.1E-13 T 06-07-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 LK06_RS24780 1ea020a9c93cec37f533b8099fe842b6 302 SUPERFAMILY SSF55120 9 232 2.4E-70 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS31975 80c9b5b07db472851caef7c94a1ac971 263 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 77 9.2E-22 T 06-07-2017 IPR025161 Putative transposase IS4/IS5 family LK06_RS31975 80c9b5b07db472851caef7c94a1ac971 263 Pfam PF01609 Transposase DDE domain 96 228 1.1E-16 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS14245 80c9b5b07db472851caef7c94a1ac971 263 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 77 9.2E-22 T 06-07-2017 IPR025161 Putative transposase IS4/IS5 family LK06_RS14245 80c9b5b07db472851caef7c94a1ac971 263 Pfam PF01609 Transposase DDE domain 96 228 1.1E-16 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS28980 80c9b5b07db472851caef7c94a1ac971 263 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 77 9.2E-22 T 06-07-2017 IPR025161 Putative transposase IS4/IS5 family LK06_RS28980 80c9b5b07db472851caef7c94a1ac971 263 Pfam PF01609 Transposase DDE domain 96 228 1.1E-16 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS03495 80c9b5b07db472851caef7c94a1ac971 263 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 77 9.2E-22 T 06-07-2017 IPR025161 Putative transposase IS4/IS5 family LK06_RS03495 80c9b5b07db472851caef7c94a1ac971 263 Pfam PF01609 Transposase DDE domain 96 228 1.1E-16 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS13815 94ef274322c827d7817d66dcc9ce9628 377 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 13 372 4.6E-143 T 06-07-2017 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated LK06_RS13815 94ef274322c827d7817d66dcc9ce9628 377 Pfam PF10103 Zinicin-like metallopeptidase 13 368 9.1E-121 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 LK06_RS13815 94ef274322c827d7817d66dcc9ce9628 377 SUPERFAMILY SSF55486 12 371 1.17E-105 T 06-07-2017 LK06_RS13815 94ef274322c827d7817d66dcc9ce9628 377 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 13 372 6.9E-126 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 LK06_RS13125 13448e76d32c891b838ba92134fdac17 438 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 13 427 1.6E-180 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 LK06_RS13125 13448e76d32c891b838ba92134fdac17 438 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 12 433 96.432 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 LK06_RS13125 13448e76d32c891b838ba92134fdac17 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 243 279 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS13125 13448e76d32c891b838ba92134fdac17 438 Gene3D G3DSA:3.40.640.10 79 325 1.0E-77 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS13125 13448e76d32c891b838ba92134fdac17 438 Gene3D G3DSA:3.90.1150.10 10 78 1.6E-37 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS13125 13448e76d32c891b838ba92134fdac17 438 Gene3D G3DSA:3.90.1150.10 327 429 1.6E-37 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS13125 13448e76d32c891b838ba92134fdac17 438 Pfam PF00202 Aminotransferase class-III 42 426 5.0E-84 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS13125 13448e76d32c891b838ba92134fdac17 438 SUPERFAMILY SSF53383 10 429 3.7E-118 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS07635 4713c05ae7125d0f8c6a2a525a83d618 133 SMART SM00448 5 121 0.0018 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS07635 4713c05ae7125d0f8c6a2a525a83d618 133 SUPERFAMILY SSF52172 4 130 7.54E-11 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS07635 4713c05ae7125d0f8c6a2a525a83d618 133 Gene3D G3DSA:3.40.50.2300 4 129 1.4E-12 T 06-07-2017 LK06_RS11035 20586c6cbcc1b329a651210e963ebc89 357 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 125 6.8E-21 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 LK06_RS11035 20586c6cbcc1b329a651210e963ebc89 357 Gene3D G3DSA:3.30.360.10 309 352 2.4E-37 T 06-07-2017 LK06_RS11035 20586c6cbcc1b329a651210e963ebc89 357 Gene3D G3DSA:3.30.360.10 136 277 2.4E-37 T 06-07-2017 LK06_RS11035 20586c6cbcc1b329a651210e963ebc89 357 SUPERFAMILY SSF51735 5 162 5.21E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11035 20586c6cbcc1b329a651210e963ebc89 357 SUPERFAMILY SSF55347 134 274 5.07E-28 T 06-07-2017 LK06_RS11035 20586c6cbcc1b329a651210e963ebc89 357 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 225 1.3E-10 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 LK06_RS11035 20586c6cbcc1b329a651210e963ebc89 357 Gene3D G3DSA:3.40.50.720 4 135 4.5E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS10995 6bc232263a67f94b4f2fed100a2a3f38 227 Gene3D G3DSA:2.40.260.10 78 208 1.7E-4 T 06-07-2017 IPR023365 Sortase domain LK06_RS10995 6bc232263a67f94b4f2fed100a2a3f38 227 Pfam PF04203 Sortase family 78 220 2.6E-14 T 06-07-2017 IPR005754 Sortase family LK06_RS10995 6bc232263a67f94b4f2fed100a2a3f38 227 SUPERFAMILY SSF63817 72 222 3.61E-11 T 06-07-2017 IPR023365 Sortase domain LK06_RS07430 aefa8f4407c4a40f7a523a12327dab14 386 Gene3D G3DSA:3.30.9.10 93 146 1.2E-9 T 06-07-2017 LK06_RS07430 aefa8f4407c4a40f7a523a12327dab14 386 Gene3D G3DSA:3.30.9.10 226 317 1.2E-9 T 06-07-2017 LK06_RS07430 aefa8f4407c4a40f7a523a12327dab14 386 Gene3D G3DSA:3.50.50.60 147 225 9.3E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07430 aefa8f4407c4a40f7a523a12327dab14 386 Gene3D G3DSA:3.50.50.60 321 377 9.3E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07430 aefa8f4407c4a40f7a523a12327dab14 386 Gene3D G3DSA:3.50.50.60 4 85 9.3E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07430 aefa8f4407c4a40f7a523a12327dab14 386 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 8 363 6.4E-125 T 06-07-2017 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 LK06_RS07430 aefa8f4407c4a40f7a523a12327dab14 386 Pfam PF01266 FAD dependent oxidoreductase 7 358 5.4E-66 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS07430 aefa8f4407c4a40f7a523a12327dab14 386 SUPERFAMILY SSF54373 227 319 3.66E-21 T 06-07-2017 LK06_RS07430 aefa8f4407c4a40f7a523a12327dab14 386 SUPERFAMILY SSF51905 6 226 3.63E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07430 aefa8f4407c4a40f7a523a12327dab14 386 SUPERFAMILY SSF51905 321 378 3.63E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13090 657238d4d8ed88d5267865270d46c47a 135 Gene3D G3DSA:3.30.530.20 10 130 6.5E-17 T 06-07-2017 IPR023393 START-like domain LK06_RS13090 657238d4d8ed88d5267865270d46c47a 135 SUPERFAMILY SSF55961 8 130 2.64E-15 T 06-07-2017 LK06_RS13090 657238d4d8ed88d5267865270d46c47a 135 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 23 126 1.6E-7 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase LK06_RS05515 807ae92a8c07e7feaa1e097dc3623079 286 Pfam PF01674 Lipase (class 2) 51 225 4.5E-14 T 06-07-2017 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 LK06_RS05515 807ae92a8c07e7feaa1e097dc3623079 286 Gene3D G3DSA:3.40.50.1820 32 282 2.6E-78 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS05515 807ae92a8c07e7feaa1e097dc3623079 286 SUPERFAMILY SSF53474 47 185 6.34E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS15870 778fe0a87e1d0c9d0b837def39582628 123 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 60 74 - T 06-07-2017 IPR020539 Ribonuclease P, conserved site GO:0004526 LK06_RS15870 778fe0a87e1d0c9d0b837def39582628 123 Pfam PF00825 Ribonuclease P 2 117 3.4E-29 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 LK06_RS15870 778fe0a87e1d0c9d0b837def39582628 123 SUPERFAMILY SSF54211 2 118 8.6E-26 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS15870 778fe0a87e1d0c9d0b837def39582628 123 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 41 92 3.0E-4 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 LK06_RS15870 778fe0a87e1d0c9d0b837def39582628 123 Gene3D G3DSA:3.30.230.10 2 117 1.5E-33 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS15870 778fe0a87e1d0c9d0b837def39582628 123 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 120 17.154 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 LK06_RS15870 778fe0a87e1d0c9d0b837def39582628 123 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 116 5.3E-17 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 414 2.1E-133 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 1.2E-23 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 Gene3D G3DSA:3.30.930.10 104 418 4.7E-123 T 06-07-2017 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 PIRSF PIRSF001529 1 422 4.5E-141 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 Gene3D G3DSA:1.10.287.40 2 102 4.1E-27 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 397 6.1E-30 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 SUPERFAMILY SSF46589 2 111 9.94E-24 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 SUPERFAMILY SSF55681 132 416 3.51E-84 T 06-07-2017 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 419 38.871 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 1.1E-29 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 1.1E-29 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 1.1E-29 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 1.1E-29 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LK06_RS16235 706094af4029f8e4e04d8a2c56c30239 425 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 1.1E-29 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LK06_RS31435 1335c32081fa6e81958f408aa1f1f4e1 243 SUPERFAMILY SSF52172 14 139 1.41E-45 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS31435 1335c32081fa6e81958f408aa1f1f4e1 243 SMART SM00448 17 127 1.1E-48 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS31435 1335c32081fa6e81958f408aa1f1f4e1 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 236 2.1E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS31435 1335c32081fa6e81958f408aa1f1f4e1 243 SMART SM00862 161 236 2.1E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS31435 1335c32081fa6e81958f408aa1f1f4e1 243 Gene3D G3DSA:1.10.10.10 141 239 5.4E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31435 1335c32081fa6e81958f408aa1f1f4e1 243 SUPERFAMILY SSF46894 143 237 2.66E-28 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS31435 1335c32081fa6e81958f408aa1f1f4e1 243 Pfam PF00072 Response regulator receiver domain 19 127 6.1E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS31435 1335c32081fa6e81958f408aa1f1f4e1 243 Gene3D G3DSA:3.40.50.2300 14 137 4.9E-43 T 06-07-2017 LK06_RS28725 6ebaecb50792f460707aa5c0dc2b046f 320 Gene3D G3DSA:1.10.600.10 16 304 5.1E-81 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS28725 6ebaecb50792f460707aa5c0dc2b046f 320 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 176 201 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LK06_RS28725 6ebaecb50792f460707aa5c0dc2b046f 320 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 141 156 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LK06_RS28725 6ebaecb50792f460707aa5c0dc2b046f 320 Pfam PF00494 Squalene/phytoene synthase 28 287 7.8E-73 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 LK06_RS28725 6ebaecb50792f460707aa5c0dc2b046f 320 SUPERFAMILY SSF48576 18 303 2.59E-72 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS28725 6ebaecb50792f460707aa5c0dc2b046f 320 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 26 298 1.6E-94 T 06-07-2017 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 Gene3D G3DSA:3.90.110.10 164 439 3.4E-88 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 135 165 - T 06-07-2017 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 1.6E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 1.6E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 1.6E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 1.6E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 186 198 1.6E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 1.6E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 160 171 1.6E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 421 1.1E-43 T 06-07-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 Gene3D G3DSA:3.40.50.720 1 163 3.8E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 Pfam PF02056 Family 4 glycosyl hydrolase 2 180 2.7E-42 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 SUPERFAMILY SSF56327 164 440 2.73E-60 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 LK06_RS28435 ed751f86b4160fed3176f44ace2319ed 445 SUPERFAMILY SSF51735 2 163 1.41E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 273 327 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 Gene3D G3DSA:1.20.210.10 33 559 7.5E-195 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 52 496 2.7E-144 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 SUPERFAMILY SSF81442 40 551 7.33E-177 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 339 360 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 317 332 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 160 172 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 210 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 374 392 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 221 240 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 452 473 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 43 68 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 271 292 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 117 141 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 402 421 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 90 113 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 250 271 9.4E-103 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS29350 13131bbe9c3ff934db44faecac7441be 570 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 44 548 3.9E-212 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 LK06_RS19510 ed79970202e233619d1e751cd15c1ace 221 SUPERFAMILY SSF55874 39 145 4.52E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS19510 ed79970202e233619d1e751cd15c1ace 221 Pfam PF13581 Histidine kinase-like ATPase domain 20 142 1.1E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS19510 ed79970202e233619d1e751cd15c1ace 221 Gene3D G3DSA:3.30.565.10 41 149 5.8E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01795 178cd447090708aab786a2de0d3e87ae 190 SUPERFAMILY SSF46689 3 80 1.95E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01795 178cd447090708aab786a2de0d3e87ae 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01795 178cd447090708aab786a2de0d3e87ae 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01795 178cd447090708aab786a2de0d3e87ae 190 SUPERFAMILY SSF48498 81 185 1.19E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS01795 178cd447090708aab786a2de0d3e87ae 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 4.4E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01795 178cd447090708aab786a2de0d3e87ae 190 Gene3D G3DSA:1.10.357.10 6 178 9.8E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS20075 86dedb774db4a5506be915328c792133 218 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 202 3.3E-56 T 06-07-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 LK06_RS20075 86dedb774db4a5506be915328c792133 218 SUPERFAMILY SSF53067 2 102 1.51E-22 T 06-07-2017 LK06_RS20075 86dedb774db4a5506be915328c792133 218 Pfam PF00814 Glycoprotease family 32 156 3.5E-30 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 LK06_RS20075 86dedb774db4a5506be915328c792133 218 Gene3D G3DSA:3.30.420.40 2 127 2.1E-36 T 06-07-2017 LK06_RS20075 86dedb774db4a5506be915328c792133 218 SUPERFAMILY SSF53067 108 200 4.4E-12 T 06-07-2017 LK06_RS31625 5b788f65541ffd8b3293c43fc5e6096e 272 Gene3D G3DSA:3.40.50.300 11 227 3.2E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31625 5b788f65541ffd8b3293c43fc5e6096e 272 Pfam PF00005 ABC transporter 28 178 5.6E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS31625 5b788f65541ffd8b3293c43fc5e6096e 272 SMART SM00382 37 226 1.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS31625 5b788f65541ffd8b3293c43fc5e6096e 272 SUPERFAMILY SSF52540 11 235 2.88E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22385 96bfe29d3e42232a68eec372c9164c42 100 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 10 84 1.4E-30 T 06-07-2017 IPR024020 Anti sigma-R factor, mycothiol system,RsrA LK06_RS22385 96bfe29d3e42232a68eec372c9164c42 100 Pfam PF13490 Putative zinc-finger 11 44 1.0E-8 T 06-07-2017 IPR027383 Putative zinc-finger LK06_RS22385 96bfe29d3e42232a68eec372c9164c42 100 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 4 85 3.8E-35 T 06-07-2017 IPR014295 Anti-sigma factor LK06_RS13320 78cba2e657c07059615df290105603e7 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS13320 78cba2e657c07059615df290105603e7 258 Pfam PF00106 short chain dehydrogenase 12 192 5.2E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13320 78cba2e657c07059615df290105603e7 258 SUPERFAMILY SSF51735 11 234 4.77E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13320 78cba2e657c07059615df290105603e7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 8.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13320 78cba2e657c07059615df290105603e7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 8.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13320 78cba2e657c07059615df290105603e7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13320 78cba2e657c07059615df290105603e7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13320 78cba2e657c07059615df290105603e7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 8.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13320 78cba2e657c07059615df290105603e7 258 Gene3D G3DSA:3.40.50.720 10 235 3.1E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS18380 f5f8d29ed87fcbb01eeb6e6b8abfa928 132 SUPERFAMILY SSF47090 56 128 2.2E-16 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18380 f5f8d29ed87fcbb01eeb6e6b8abfa928 132 Pfam PF01471 Putative peptidoglycan binding domain 91 126 1.1E-12 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18380 f5f8d29ed87fcbb01eeb6e6b8abfa928 132 Gene3D G3DSA:1.10.101.10 56 129 5.5E-20 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS11330 ffcaa404a7e48eca8d0110a80e146c7a 196 Gene3D G3DSA:1.10.10.10 17 90 1.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11330 ffcaa404a7e48eca8d0110a80e146c7a 196 SUPERFAMILY SSF46785 16 131 2.1E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11330 ffcaa404a7e48eca8d0110a80e146c7a 196 SMART SM00418 16 112 1.0E-7 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS11330 ffcaa404a7e48eca8d0110a80e146c7a 196 Pfam PF12840 Helix-turn-helix domain 21 72 1.5E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06010 4ec1313166bebdb8156366f3f25c280d 393 Gene3D G3DSA:1.10.260.40 5 131 2.0E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS06010 4ec1313166bebdb8156366f3f25c280d 393 SMART SM00530 8 64 9.6E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS06010 4ec1313166bebdb8156366f3f25c280d 393 SUPERFAMILY SSF47413 3 71 6.7E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS06010 4ec1313166bebdb8156366f3f25c280d 393 Pfam PF13560 Helix-turn-helix domain 5 61 4.0E-12 T 06-07-2017 LK06_RS06135 d1aa91f060151c5f2144ed5930b24edd 597 Pfam PF00723 Glycosyl hydrolases family 15 217 587 6.8E-69 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 LK06_RS06135 d1aa91f060151c5f2144ed5930b24edd 597 SUPERFAMILY SSF48208 190 590 1.85E-103 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS06135 d1aa91f060151c5f2144ed5930b24edd 597 Gene3D G3DSA:1.50.10.10 213 588 1.5E-82 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 LK06_RS25655 39693ecdce23fa8ef1b1840159f1e72e 527 Gene3D G3DSA:2.30.38.10 352 422 3.1E-24 T 06-07-2017 LK06_RS25655 39693ecdce23fa8ef1b1840159f1e72e 527 Pfam PF00501 AMP-binding enzyme 24 432 1.6E-63 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS25655 39693ecdce23fa8ef1b1840159f1e72e 527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS25655 39693ecdce23fa8ef1b1840159f1e72e 527 SUPERFAMILY SSF56801 18 526 2.88E-106 T 06-07-2017 LK06_RS25655 39693ecdce23fa8ef1b1840159f1e72e 527 Gene3D G3DSA:3.30.300.30 429 525 2.3E-21 T 06-07-2017 LK06_RS25655 39693ecdce23fa8ef1b1840159f1e72e 527 Gene3D G3DSA:3.40.50.980 181 351 7.4E-21 T 06-07-2017 LK06_RS25655 39693ecdce23fa8ef1b1840159f1e72e 527 Gene3D G3DSA:3.40.50.980 23 180 2.9E-21 T 06-07-2017 LK06_RS25655 39693ecdce23fa8ef1b1840159f1e72e 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 516 1.8E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS26210 f0d4d87f69f4656e38dfda1205cc9f51 244 Gene3D G3DSA:3.40.50.150 7 224 2.2E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26210 f0d4d87f69f4656e38dfda1205cc9f51 244 Pfam PF13649 Methyltransferase domain 43 139 1.2E-21 T 06-07-2017 LK06_RS26210 f0d4d87f69f4656e38dfda1205cc9f51 244 SUPERFAMILY SSF53335 197 223 1.89E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26210 f0d4d87f69f4656e38dfda1205cc9f51 244 SUPERFAMILY SSF53335 7 154 1.89E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19985 a4b89f9aa538d5b8f34d6660ee32a981 429 SUPERFAMILY SSF53335 146 411 2.97E-75 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19985 a4b89f9aa538d5b8f34d6660ee32a981 429 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 155 369 0.0071 T 06-07-2017 IPR020803 Polyketide synthase, methyltransferase domain LK06_RS19985 a4b89f9aa538d5b8f34d6660ee32a981 429 PIRSF PIRSF003085 4 428 4.1E-131 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 LK06_RS19985 a4b89f9aa538d5b8f34d6660ee32a981 429 Pfam PF02353 Mycolic acid cyclopropane synthetase 138 407 2.8E-92 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19985 a4b89f9aa538d5b8f34d6660ee32a981 429 Gene3D G3DSA:3.40.50.150 136 409 1.5E-91 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS12765 5782dec4ca3162bd25a7a3e54f75df53 437 Gene3D G3DSA:3.30.1490.20 135 219 1.1E-6 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS12765 5782dec4ca3162bd25a7a3e54f75df53 437 SUPERFAMILY SSF56059 140 348 2.47E-20 T 06-07-2017 LK06_RS12765 5782dec4ca3162bd25a7a3e54f75df53 437 Gene3D G3DSA:3.30.470.20 246 339 5.5E-11 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS04590 38d6561c97215422046cc79cdca9a272 240 SUPERFAMILY SSF161098 3 197 3.4E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS04590 38d6561c97215422046cc79cdca9a272 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 213 1.3E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS04590 38d6561c97215422046cc79cdca9a272 240 Gene3D G3DSA:1.10.3720.10 3 210 1.4E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS00340 c76c64dd6e0f9999aa7ebe278862ba36 423 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 386 397 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS00340 c76c64dd6e0f9999aa7ebe278862ba36 423 Gene3D G3DSA:3.30.70.20 292 327 8.6E-10 T 06-07-2017 LK06_RS00340 c76c64dd6e0f9999aa7ebe278862ba36 423 Gene3D G3DSA:3.30.70.20 377 402 8.6E-10 T 06-07-2017 LK06_RS00340 c76c64dd6e0f9999aa7ebe278862ba36 423 Pfam PF17179 4Fe-4S dicluster domain 306 400 3.1E-34 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LK06_RS00340 c76c64dd6e0f9999aa7ebe278862ba36 423 SUPERFAMILY SSF46548 297 410 6.8E-16 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 LK06_RS00340 c76c64dd6e0f9999aa7ebe278862ba36 423 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 307 318 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS10155 adb371a281e45413eab3a0c5dab8ad07 821 Pfam PF16918 Protein kinase G tetratricopeptide repeat 512 819 1.1E-88 T 06-07-2017 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 LK06_RS10155 adb371a281e45413eab3a0c5dab8ad07 821 SUPERFAMILY SSF48452 584 685 1.95E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS10155 adb371a281e45413eab3a0c5dab8ad07 821 Gene3D G3DSA:3.30.200.20 183 275 1.1E-12 T 06-07-2017 LK06_RS10155 adb371a281e45413eab3a0c5dab8ad07 821 SMART SM00220 188 443 2.6E-13 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS10155 adb371a281e45413eab3a0c5dab8ad07 821 Pfam PF00069 Protein kinase domain 192 389 1.6E-24 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS10155 adb371a281e45413eab3a0c5dab8ad07 821 Gene3D G3DSA:1.25.40.10 559 689 3.7E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS10155 adb371a281e45413eab3a0c5dab8ad07 821 SUPERFAMILY SSF56112 179 447 1.12E-39 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS10155 adb371a281e45413eab3a0c5dab8ad07 821 Gene3D G3DSA:1.10.510.10 276 388 2.1E-20 T 06-07-2017 LK06_RS10155 adb371a281e45413eab3a0c5dab8ad07 821 Pfam PF16919 Protein kinase G rubredoxin domain 52 187 3.9E-40 T 06-07-2017 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 LK06_RS17430 92fb5a10a4346b6ca1a8d51259cd9b56 256 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 86 91 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 LK06_RS17430 92fb5a10a4346b6ca1a8d51259cd9b56 256 Pfam PF13365 Trypsin-like peptidase domain 76 221 3.6E-9 T 06-07-2017 LK06_RS17430 92fb5a10a4346b6ca1a8d51259cd9b56 256 Gene3D G3DSA:2.40.10.10 67 142 1.3E-10 T 06-07-2017 LK06_RS17430 92fb5a10a4346b6ca1a8d51259cd9b56 256 Gene3D G3DSA:2.40.10.10 166 231 8.7E-7 T 06-07-2017 LK06_RS17430 92fb5a10a4346b6ca1a8d51259cd9b56 256 SUPERFAMILY SSF50494 67 229 1.21E-23 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS04275 054dcbc585bfbe2f45e6cfa17340bc2a 171 SMART SM01323 2 82 1.4E-24 T 06-07-2017 IPR003849 Preprotein translocase YajC LK06_RS04275 054dcbc585bfbe2f45e6cfa17340bc2a 171 Pfam PF02699 Preprotein translocase subunit 5 79 4.5E-18 T 06-07-2017 IPR003849 Preprotein translocase YajC LK06_RS04275 054dcbc585bfbe2f45e6cfa17340bc2a 171 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 4 82 2.9E-16 T 06-07-2017 IPR003849 Preprotein translocase YajC LK06_RS17475 8373163a105b1ac14e91d4a97364565e 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 44 8.5E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17475 8373163a105b1ac14e91d4a97364565e 178 SUPERFAMILY SSF46689 2 70 1.69E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS17475 8373163a105b1ac14e91d4a97364565e 178 SUPERFAMILY SSF48498 64 176 6.23E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS17475 8373163a105b1ac14e91d4a97364565e 178 Gene3D G3DSA:1.10.357.10 2 177 5.3E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS18140 0c2bd61900f5dc1f4ef6d43ebe8bcabc 312 Pfam PF00005 ABC transporter 18 156 6.2E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS18140 0c2bd61900f5dc1f4ef6d43ebe8bcabc 312 Gene3D G3DSA:3.40.50.300 1 224 1.0E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18140 0c2bd61900f5dc1f4ef6d43ebe8bcabc 312 SUPERFAMILY SSF52540 2 222 2.98E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18140 0c2bd61900f5dc1f4ef6d43ebe8bcabc 312 SMART SM00382 26 204 6.6E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS11185 8e5547eb5445ed0d11241110a97e7fc3 432 Pfam PF13704 Glycosyl transferase family 2 68 155 4.5E-7 T 06-07-2017 LK06_RS11185 8e5547eb5445ed0d11241110a97e7fc3 432 SUPERFAMILY SSF53448 59 179 3.83E-12 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11185 8e5547eb5445ed0d11241110a97e7fc3 432 Gene3D G3DSA:3.90.550.10 60 157 2.7E-6 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS27565 c9f0a627a15e8ab8eddb344b9fc6446b 334 SUPERFAMILY SSF51735 2 147 3.72E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27565 c9f0a627a15e8ab8eddb344b9fc6446b 334 Gene3D G3DSA:3.30.360.10 131 327 5.9E-48 T 06-07-2017 LK06_RS27565 c9f0a627a15e8ab8eddb344b9fc6446b 334 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 118 5.9E-19 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 LK06_RS27565 c9f0a627a15e8ab8eddb344b9fc6446b 334 SUPERFAMILY SSF55347 129 291 2.13E-24 T 06-07-2017 LK06_RS27565 c9f0a627a15e8ab8eddb344b9fc6446b 334 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 130 236 1.5E-9 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 LK06_RS27565 c9f0a627a15e8ab8eddb344b9fc6446b 334 Gene3D G3DSA:3.40.50.720 1 130 7.0E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05495 db9fb1e78bfa564c46497de10b8461c2 166 Pfam PF04167 Protein of unknown function (DUF402) 62 129 1.0E-19 T 06-07-2017 IPR007295 Domain of unknown function DUF402 LK06_RS05495 db9fb1e78bfa564c46497de10b8461c2 166 Gene3D G3DSA:2.40.380.10 10 155 1.3E-35 T 06-07-2017 IPR007295 Domain of unknown function DUF402 LK06_RS05495 db9fb1e78bfa564c46497de10b8461c2 166 SUPERFAMILY SSF159234 30 134 1.7E-13 T 06-07-2017 LK06_RS01640 a585a0772fb39a2e0f6ebe7046f07721 514 SUPERFAMILY SSF103473 36 227 1.96E-29 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS01640 a585a0772fb39a2e0f6ebe7046f07721 514 SUPERFAMILY SSF103473 273 484 1.96E-29 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS01640 a585a0772fb39a2e0f6ebe7046f07721 514 Gene3D G3DSA:1.20.1250.20 37 216 7.5E-15 T 06-07-2017 LK06_RS01640 a585a0772fb39a2e0f6ebe7046f07721 514 Pfam PF07690 Major Facilitator Superfamily 40 404 2.6E-19 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS01640 a585a0772fb39a2e0f6ebe7046f07721 514 Gene3D G3DSA:1.20.1250.20 296 487 2.4E-4 T 06-07-2017 LK06_RS10675 80c248ad2d9ee06ce427ba0e9966e636 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 348 4.8E-32 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LK06_RS10675 80c248ad2d9ee06ce427ba0e9966e636 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 440 459 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 LK06_RS10675 80c248ad2d9ee06ce427ba0e9966e636 562 SUPERFAMILY SSF52518 384 549 1.32E-44 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS10675 80c248ad2d9ee06ce427ba0e9966e636 562 Gene3D G3DSA:3.40.50.1220 210 362 6.1E-44 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS10675 80c248ad2d9ee06ce427ba0e9966e636 562 SUPERFAMILY SSF52518 27 203 3.93E-40 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS10675 80c248ad2d9ee06ce427ba0e9966e636 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 408 547 1.4E-33 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LK06_RS10675 80c248ad2d9ee06ce427ba0e9966e636 562 Gene3D G3DSA:3.40.50.970 383 547 1.5E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS10675 80c248ad2d9ee06ce427ba0e9966e636 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 27 196 1.2E-44 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LK06_RS10675 80c248ad2d9ee06ce427ba0e9966e636 562 Gene3D G3DSA:3.40.50.970 26 200 1.4E-49 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS10675 80c248ad2d9ee06ce427ba0e9966e636 562 SUPERFAMILY SSF52467 181 374 4.73E-37 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS01270 563567a5e456b05d7e538cdb88607447 247 Pfam PF02585 GlcNAc-PI de-N-acetylase 20 148 1.8E-27 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 LK06_RS01270 563567a5e456b05d7e538cdb88607447 247 Gene3D G3DSA:3.40.50.10320 15 245 2.2E-52 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 LK06_RS01270 563567a5e456b05d7e538cdb88607447 247 SUPERFAMILY SSF102588 16 226 6.54E-45 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 LK06_RS13175 77c0badd6e8d097ca158ee3dc04dd74c 324 Pfam PF13560 Helix-turn-helix domain 16 71 3.1E-9 T 06-07-2017 LK06_RS13175 77c0badd6e8d097ca158ee3dc04dd74c 324 SMART SM00530 20 75 6.4E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS13175 77c0badd6e8d097ca158ee3dc04dd74c 324 SUPERFAMILY SSF47413 16 69 2.62E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS13175 77c0badd6e8d097ca158ee3dc04dd74c 324 Gene3D G3DSA:1.10.260.40 10 62 2.6E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS09690 7220c47e13f1eb25c8b0e863032de305 153 Pfam PF00872 Transposase, Mutator family 2 118 8.7E-34 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 7.9E-34 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 7.9E-34 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 7.9E-34 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 7.9E-34 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 292 3.1E-126 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 SMART SM00881 4 104 2.1E-30 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 Pfam PF00549 CoA-ligase 158 275 6.2E-14 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 SUPERFAMILY SSF51735 1 128 2.4E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 06-07-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 SUPERFAMILY SSF52210 129 289 9.42E-48 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 Pfam PF02629 CoA binding domain 6 103 1.2E-25 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 PIRSF PIRSF001553 1 294 1.1E-115 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 Gene3D G3DSA:3.40.50.261 126 291 3.0E-67 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 LK06_RS20335 6025287d4be783c6b90d35c195b5d753 294 Gene3D G3DSA:3.40.50.720 3 125 3.4E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02490 1e774d22029b023245a2851a9733239a 157 Gene3D G3DSA:3.10.129.10 2 140 4.0E-27 T 06-07-2017 IPR029069 HotDog domain LK06_RS02490 1e774d22029b023245a2851a9733239a 157 SUPERFAMILY SSF54637 4 140 5.48E-25 T 06-07-2017 IPR029069 HotDog domain LK06_RS02490 1e774d22029b023245a2851a9733239a 157 PIRSF PIRSF003230 1 145 1.4E-19 T 06-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 LK06_RS02490 1e774d22029b023245a2851a9733239a 157 Pfam PF13279 Thioesterase-like superfamily 11 136 1.4E-6 T 06-07-2017 LK06_RS06455 d8e4990f82f42078db077840eab30f1d 155 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 140 5.4E-49 T 06-07-2017 LK06_RS06455 d8e4990f82f42078db077840eab30f1d 155 Gene3D G3DSA:3.90.1010.10 5 147 6.8E-46 T 06-07-2017 LK06_RS06455 d8e4990f82f42078db077840eab30f1d 155 Pfam PF01592 NifU-like N terminal domain 6 129 2.2E-27 T 06-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 LK06_RS06455 d8e4990f82f42078db077840eab30f1d 155 SUPERFAMILY SSF82649 2 142 1.44E-44 T 06-07-2017 LK06_RS29995 fa107022bbe147a2691a1019652f3efe 413 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 15 310 8.1E-83 T 06-07-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 LK06_RS29995 fa107022bbe147a2691a1019652f3efe 413 SUPERFAMILY SSF51905 272 351 1.13E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29995 fa107022bbe147a2691a1019652f3efe 413 SUPERFAMILY SSF51905 15 183 1.13E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29995 fa107022bbe147a2691a1019652f3efe 413 Pfam PF12831 FAD dependent oxidoreductase 16 166 3.8E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29995 fa107022bbe147a2691a1019652f3efe 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 1.4E-12 T 06-07-2017 LK06_RS29995 fa107022bbe147a2691a1019652f3efe 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.4E-12 T 06-07-2017 LK06_RS29995 fa107022bbe147a2691a1019652f3efe 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 1.4E-12 T 06-07-2017 LK06_RS29995 fa107022bbe147a2691a1019652f3efe 413 Gene3D G3DSA:3.30.9.10 169 319 4.2E-25 T 06-07-2017 LK06_RS29995 fa107022bbe147a2691a1019652f3efe 413 Gene3D G3DSA:3.50.50.60 14 168 1.3E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29665 3f5b3cf5d5481c8fe48a3f3c5bcb777a 289 Gene3D G3DSA:3.10.129.10 4 114 6.9E-50 T 06-07-2017 IPR029069 HotDog domain LK06_RS29665 3f5b3cf5d5481c8fe48a3f3c5bcb777a 289 Gene3D G3DSA:3.10.129.10 126 287 7.6E-53 T 06-07-2017 IPR029069 HotDog domain LK06_RS29665 3f5b3cf5d5481c8fe48a3f3c5bcb777a 289 SUPERFAMILY SSF54637 117 287 2.91E-48 T 06-07-2017 IPR029069 HotDog domain LK06_RS29665 3f5b3cf5d5481c8fe48a3f3c5bcb777a 289 Pfam PF13622 Thioesterase-like superfamily 33 284 9.7E-60 T 06-07-2017 LK06_RS29665 3f5b3cf5d5481c8fe48a3f3c5bcb777a 289 SUPERFAMILY SSF54637 6 114 2.87E-43 T 06-07-2017 IPR029069 HotDog domain LK06_RS30875 cb4cddcc10ac849172cb13dcfdc75cd6 600 Gene3D G3DSA:3.10.170.10 251 407 1.6E-40 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS30875 cb4cddcc10ac849172cb13dcfdc75cd6 600 Gene3D G3DSA:1.10.390.10 421 590 8.0E-43 T 06-07-2017 LK06_RS30875 cb4cddcc10ac849172cb13dcfdc75cd6 600 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 251 403 2.2E-43 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS30875 cb4cddcc10ac849172cb13dcfdc75cd6 600 SUPERFAMILY SSF55486 247 590 3.66E-65 T 06-07-2017 LK06_RS30875 cb4cddcc10ac849172cb13dcfdc75cd6 600 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 74 111 5.4E-9 T 06-07-2017 IPR011096 FTP domain LK06_RS30875 cb4cddcc10ac849172cb13dcfdc75cd6 600 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 357 377 2.1E-7 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS30875 cb4cddcc10ac849172cb13dcfdc75cd6 600 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 395 411 2.1E-7 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS30875 cb4cddcc10ac849172cb13dcfdc75cd6 600 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 492 508 2.1E-7 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS30875 cb4cddcc10ac849172cb13dcfdc75cd6 600 Pfam PF03413 Peptidase propeptide and YPEB domain 143 195 5.3E-7 T 06-07-2017 IPR025711 PepSY domain LK06_RS30875 cb4cddcc10ac849172cb13dcfdc75cd6 600 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 422 590 1.4E-42 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 LK06_RS20935 16b2386102fe931752bc9e536319bb9b 346 SUPERFAMILY SSF50129 7 171 8.37E-55 T 06-07-2017 IPR011032 GroES-like LK06_RS20935 16b2386102fe931752bc9e536319bb9b 346 Pfam PF00107 Zinc-binding dehydrogenase 185 307 1.8E-20 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS20935 16b2386102fe931752bc9e536319bb9b 346 SUPERFAMILY SSF51735 148 311 1.08E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20935 16b2386102fe931752bc9e536319bb9b 346 Gene3D G3DSA:3.40.50.720 180 288 2.8E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20935 16b2386102fe931752bc9e536319bb9b 346 Gene3D G3DSA:3.90.180.10 2 179 4.3E-66 T 06-07-2017 IPR011032 GroES-like LK06_RS20935 16b2386102fe931752bc9e536319bb9b 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LK06_RS20935 16b2386102fe931752bc9e536319bb9b 346 SMART SM00829 14 341 3.9E-6 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS20935 16b2386102fe931752bc9e536319bb9b 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 144 5.0E-30 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS27835 d3fc53506a79d176b279dea2497bef35 52 Gene3D G3DSA:1.10.1220.10 2 41 3.3E-12 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 LK06_RS27835 d3fc53506a79d176b279dea2497bef35 52 SUPERFAMILY SSF47598 2 40 3.34E-10 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 LK06_RS27835 d3fc53506a79d176b279dea2497bef35 52 Pfam PF03869 Arc-like DNA binding domain 6 39 6.4E-7 T 06-07-2017 IPR005569 Arc-like DNA binding domain GO:0003677 LK06_RS16785 0beb74a78ab404845581e08838195438 231 SUPERFAMILY SSF52980 99 211 3.27E-13 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LK06_RS16785 0beb74a78ab404845581e08838195438 231 Gene3D G3DSA:3.40.1350.10 86 209 2.5E-19 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 LK06_RS16785 0beb74a78ab404845581e08838195438 231 Pfam PF04471 Restriction endonuclease 92 207 3.4E-18 T 06-07-2017 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 LK06_RS05995 f847fb5f4308feecada2738e784ecf52 225 SUPERFAMILY SSF56349 10 182 5.0E-23 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS05995 f847fb5f4308feecada2738e784ecf52 225 Gene3D G3DSA:1.10.443.10 11 183 4.0E-22 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS05995 f847fb5f4308feecada2738e784ecf52 225 Pfam PF00589 Phage integrase family 17 179 7.6E-10 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 Gene3D G3DSA:1.20.1260.10 1 156 2.9E-54 T 06-07-2017 IPR012347 Ferritin-related LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 1.5E-65 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 Pfam PF00210 Ferritin-like domain 8 143 1.6E-33 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 PIRSF PIRSF002560 1 157 8.4E-66 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 SUPERFAMILY SSF47240 1 155 3.48E-46 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 PRINTS PR00601 Bacterioferritin signature 3 22 1.3E-57 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 PRINTS PR00601 Bacterioferritin signature 107 127 1.3E-57 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 PRINTS PR00601 Bacterioferritin signature 23 43 1.3E-57 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 PRINTS PR00601 Bacterioferritin signature 65 85 1.3E-57 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 PRINTS PR00601 Bacterioferritin signature 44 64 1.3E-57 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 PRINTS PR00601 Bacterioferritin signature 86 106 1.3E-57 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LK06_RS07460 95f40159c56649b4dcd33657d827067f 159 PRINTS PR00601 Bacterioferritin signature 128 149 1.3E-57 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LK06_RS17690 85a05021830967c75ec44bb3d4e5c57d 413 Gene3D G3DSA:3.40.630.30 3 133 2.8E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS17690 85a05021830967c75ec44bb3d4e5c57d 413 SUPERFAMILY SSF55718 307 413 5.1E-21 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS17690 85a05021830967c75ec44bb3d4e5c57d 413 Pfam PF13527 Acetyltransferase (GNAT) domain 3 130 8.7E-28 T 06-07-2017 LK06_RS17690 85a05021830967c75ec44bb3d4e5c57d 413 Hamap MF_01812 UPF0256 protein . 1 413 47.628 T 06-07-2017 IPR022902 Uncharacterised protein family UPF0256 LK06_RS17690 85a05021830967c75ec44bb3d4e5c57d 413 SUPERFAMILY SSF55729 1 306 9.3E-58 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS17690 85a05021830967c75ec44bb3d4e5c57d 413 Pfam PF13530 Sterol carrier protein domain 182 410 2.2E-47 T 06-07-2017 IPR025559 Enhanced intracellular survival protein domain LK06_RS17690 85a05021830967c75ec44bb3d4e5c57d 413 Gene3D G3DSA:3.30.1050.10 308 402 1.6E-15 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS17690 85a05021830967c75ec44bb3d4e5c57d 413 Gene3D G3DSA:3.40.630.30 137 295 7.6E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS31600 27bb386b070c6f0ef57645a5f37dd2d5 355 Gene3D G3DSA:3.40.50.720 55 131 1.3E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31600 27bb386b070c6f0ef57645a5f37dd2d5 355 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 248 264 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LK06_RS31600 27bb386b070c6f0ef57645a5f37dd2d5 355 Gene3D G3DSA:3.40.50.720 132 310 1.9E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31600 27bb386b070c6f0ef57645a5f37dd2d5 355 SUPERFAMILY SSF51735 126 310 1.5E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31600 27bb386b070c6f0ef57645a5f37dd2d5 355 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 132 309 5.8E-55 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LK06_RS31600 27bb386b070c6f0ef57645a5f37dd2d5 355 SUPERFAMILY SSF52283 42 159 6.38E-22 T 06-07-2017 LK06_RS31600 27bb386b070c6f0ef57645a5f37dd2d5 355 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 52 341 1.1E-17 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 LK06_RS03650 49286ef54ac3b3318d9ec8f378eded3d 110 PIRSF PIRSF018579 1 110 4.1E-47 T 06-07-2017 IPR009709 Protein of unknown function DUF1290 LK06_RS03650 49286ef54ac3b3318d9ec8f378eded3d 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 8.1E-35 T 06-07-2017 IPR009709 Protein of unknown function DUF1290 LK06_RS10125 5bf6fbdb7dd61b4f986447f9f5c4c901 297 Gene3D G3DSA:1.10.3720.10 22 284 8.3E-69 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10125 5bf6fbdb7dd61b4f986447f9f5c4c901 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 290 4.8E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10125 5bf6fbdb7dd61b4f986447f9f5c4c901 297 SUPERFAMILY SSF161098 25 297 1.12E-71 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS00180 1e0f884b3fd606f18d17362c647a933f 340 Gene3D G3DSA:3.40.50.720 169 284 4.1E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00180 1e0f884b3fd606f18d17362c647a933f 340 SMART SM00829 10 334 6.7E-7 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS00180 1e0f884b3fd606f18d17362c647a933f 340 Gene3D G3DSA:3.90.180.10 1 168 2.2E-64 T 06-07-2017 IPR011032 GroES-like LK06_RS00180 1e0f884b3fd606f18d17362c647a933f 340 SUPERFAMILY SSF51735 139 303 8.55E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00180 1e0f884b3fd606f18d17362c647a933f 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 128 8.9E-32 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS00180 1e0f884b3fd606f18d17362c647a933f 340 SUPERFAMILY SSF50129 1 161 6.09E-55 T 06-07-2017 IPR011032 GroES-like LK06_RS00180 1e0f884b3fd606f18d17362c647a933f 340 Pfam PF00107 Zinc-binding dehydrogenase 175 298 3.8E-26 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS00180 1e0f884b3fd606f18d17362c647a933f 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LK06_RS32310 61a6acc67c89e578fb8eedad422a1772 258 Pfam PF00872 Transposase, Mutator family 102 223 1.8E-40 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 LK06_RS19915 7bad03a439026a2e9ecfffeb063af384 275 Gene3D G3DSA:3.20.20.80 47 268 2.6E-44 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS19915 7bad03a439026a2e9ecfffeb063af384 275 SUPERFAMILY SSF51445 47 268 2.11E-39 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS19915 7bad03a439026a2e9ecfffeb063af384 275 Pfam PF08924 Domain of unknown function (DUF1906) 60 194 5.8E-36 T 06-07-2017 IPR015020 Protein of unknown function DUF1906 LK06_RS11345 f9b79441b5a25aa24328c4771aabed46 213 Gene3D G3DSA:1.10.10.10 5 76 2.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11345 f9b79441b5a25aa24328c4771aabed46 213 Pfam PF09339 IclR helix-turn-helix domain 8 58 2.1E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS11345 f9b79441b5a25aa24328c4771aabed46 213 SMART SM00346 6 93 3.7E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS11345 f9b79441b5a25aa24328c4771aabed46 213 Gene3D G3DSA:3.30.450.40 157 212 1.1E-4 T 06-07-2017 IPR029016 GAF domain-like LK06_RS11345 f9b79441b5a25aa24328c4771aabed46 213 SUPERFAMILY SSF55781 77 212 1.77E-18 T 06-07-2017 IPR029016 GAF domain-like LK06_RS11345 f9b79441b5a25aa24328c4771aabed46 213 Gene3D G3DSA:3.30.450.40 80 154 1.1E-14 T 06-07-2017 IPR029016 GAF domain-like LK06_RS11345 f9b79441b5a25aa24328c4771aabed46 213 SUPERFAMILY SSF46785 7 76 1.04E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23790 cd47fc0184e2583852c8f53962127726 443 ProSitePatterns PS00211 ABC transporters family signature. 190 204 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS23790 cd47fc0184e2583852c8f53962127726 443 Gene3D G3DSA:3.40.50.300 38 291 2.8E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23790 cd47fc0184e2583852c8f53962127726 443 SUPERFAMILY SSF52540 39 289 4.13E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23790 cd47fc0184e2583852c8f53962127726 443 SMART SM00382 75 267 7.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS23790 cd47fc0184e2583852c8f53962127726 443 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 269 337 2.0E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS23790 cd47fc0184e2583852c8f53962127726 443 Pfam PF00005 ABC transporter 67 217 1.2E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS23790 cd47fc0184e2583852c8f53962127726 443 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 267 356 1.0E-27 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS03655 d3dcad945e4f74798ecc5636c94521a1 308 Pfam PF05949 Bacterial protein of unknown function (DUF881) 141 285 5.2E-39 T 06-07-2017 IPR010273 Protein of unknown function DUF881 LK06_RS13250 3eb1e2582f95764eb945ef467dac1f4a 87 Pfam PF13560 Helix-turn-helix domain 4 71 6.4E-7 T 06-07-2017 LK06_RS13250 3eb1e2582f95764eb945ef467dac1f4a 87 Gene3D G3DSA:1.10.260.40 7 41 2.1E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS13250 3eb1e2582f95764eb945ef467dac1f4a 87 SUPERFAMILY SSF47413 4 43 1.47E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS02930 fb6e1249c162f87888a9db27b6e00d63 376 SUPERFAMILY SSF48452 171 271 5.14E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS02930 fb6e1249c162f87888a9db27b6e00d63 376 Gene3D G3DSA:3.90.550.10 2 86 3.0E-7 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS02930 fb6e1249c162f87888a9db27b6e00d63 376 SUPERFAMILY SSF53448 1 94 3.19E-13 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS02930 fb6e1249c162f87888a9db27b6e00d63 376 Pfam PF00535 Glycosyl transferase family 2 1 88 1.3E-9 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS02930 fb6e1249c162f87888a9db27b6e00d63 376 Gene3D G3DSA:1.25.40.10 171 268 1.0E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS10840 9725003bb58467afe8ef08ed3e379eaa 242 Gene3D G3DSA:1.10.10.10 130 231 6.8E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS10840 9725003bb58467afe8ef08ed3e379eaa 242 Pfam PF00072 Response regulator receiver domain 7 115 2.8E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS10840 9725003bb58467afe8ef08ed3e379eaa 242 Gene3D G3DSA:3.40.50.2300 3 126 1.8E-36 T 06-07-2017 LK06_RS10840 9725003bb58467afe8ef08ed3e379eaa 242 SMART SM00862 153 228 4.4E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS10840 9725003bb58467afe8ef08ed3e379eaa 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 226 2.4E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS10840 9725003bb58467afe8ef08ed3e379eaa 242 SUPERFAMILY SSF52172 3 170 3.27E-38 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS10840 9725003bb58467afe8ef08ed3e379eaa 242 SMART SM00448 5 115 3.7E-36 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS16120 930f05055d09b1e55923f922a28a7c35 370 Gene3D G3DSA:3.40.50.2300 80 190 1.6E-9 T 06-07-2017 LK06_RS16120 930f05055d09b1e55923f922a28a7c35 370 SMART SM00354 23 93 2.0E-20 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS16120 930f05055d09b1e55923f922a28a7c35 370 SUPERFAMILY SSF47413 23 81 2.39E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS16120 930f05055d09b1e55923f922a28a7c35 370 Pfam PF00356 Bacterial regulatory proteins, lacI family 26 70 7.5E-14 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS16120 930f05055d09b1e55923f922a28a7c35 370 Pfam PF13377 Periplasmic binding protein-like domain 193 352 5.3E-30 T 06-07-2017 LK06_RS16120 930f05055d09b1e55923f922a28a7c35 370 Gene3D G3DSA:3.40.50.2300 191 353 1.0E-32 T 06-07-2017 LK06_RS16120 930f05055d09b1e55923f922a28a7c35 370 ProSitePatterns PS00356 LacI-type HTH domain signature. 26 44 - T 06-07-2017 LK06_RS16120 930f05055d09b1e55923f922a28a7c35 370 SUPERFAMILY SSF53822 102 357 2.72E-35 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS16120 930f05055d09b1e55923f922a28a7c35 370 Gene3D G3DSA:1.10.260.40 25 79 1.8E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS08890 ea89b202790f0951d6b62c833bc1c719 340 Pfam PF16884 N-terminal domain of oxidoreductase 12 118 4.1E-41 T 06-07-2017 LK06_RS08890 ea89b202790f0951d6b62c833bc1c719 340 SMART SM00829 25 338 1.0E-8 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS08890 ea89b202790f0951d6b62c833bc1c719 340 Gene3D G3DSA:3.90.180.10 9 146 1.0E-54 T 06-07-2017 IPR011032 GroES-like LK06_RS08890 ea89b202790f0951d6b62c833bc1c719 340 SUPERFAMILY SSF51735 129 306 6.73E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08890 ea89b202790f0951d6b62c833bc1c719 340 Gene3D G3DSA:3.40.50.720 147 308 6.5E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08890 ea89b202790f0951d6b62c833bc1c719 340 SUPERFAMILY SSF50129 11 145 1.38E-40 T 06-07-2017 IPR011032 GroES-like LK06_RS08890 ea89b202790f0951d6b62c833bc1c719 340 Pfam PF00107 Zinc-binding dehydrogenase 164 292 8.9E-25 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 SUPERFAMILY SSF55486 233 558 9.16E-83 T 06-07-2017 LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 95 135 6.2E-13 T 06-07-2017 IPR011096 FTP domain LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 SUPERFAMILY SSF49785 578 683 1.4E-26 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 460 476 2.4E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 336 356 2.4E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 372 388 2.4E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 393 404 2.4E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 384 558 2.7E-55 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 Gene3D G3DSA:1.10.390.10 386 558 3.3E-53 T 06-07-2017 LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 Gene3D G3DSA:2.60.120.260 584 683 3.9E-18 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 Pfam PF01483 Proprotein convertase P-domain 603 683 5.1E-22 T 06-07-2017 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 Gene3D G3DSA:3.10.170.10 233 385 6.6E-45 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS23650 df0f98f191d5372e00f205faae14341c 684 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 234 381 4.8E-47 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS04845 49938e2bef73af02af4b1b3203a81ed1 395 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 49 393 3.6E-101 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 LK06_RS04845 49938e2bef73af02af4b1b3203a81ed1 395 Gene3D G3DSA:3.40.50.200 35 334 2.4E-81 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS04845 49938e2bef73af02af4b1b3203a81ed1 395 PRINTS PR00723 Subtilisin serine protease family (S8) signature 272 288 7.6E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS04845 49938e2bef73af02af4b1b3203a81ed1 395 PRINTS PR00723 Subtilisin serine protease family (S8) signature 100 113 7.6E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS04845 49938e2bef73af02af4b1b3203a81ed1 395 PRINTS PR00723 Subtilisin serine protease family (S8) signature 60 79 7.6E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS04845 49938e2bef73af02af4b1b3203a81ed1 395 SUPERFAMILY SSF52743 42 336 6.94E-83 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS04845 49938e2bef73af02af4b1b3203a81ed1 395 Pfam PF00082 Subtilase family 60 323 2.0E-49 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS04845 49938e2bef73af02af4b1b3203a81ed1 395 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 65 76 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 413 3.2E-197 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 Gene3D G3DSA:1.10.8.60 317 416 2.7E-35 T 06-07-2017 LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 318 395 4.2E-15 T 06-07-2017 IPR019489 Clp ATPase, C-terminal LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 Pfam PF07724 AAA domain (Cdc48 subfamily) 115 312 1.8E-50 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 SUPERFAMILY SSF57716 11 46 1.37E-11 T 06-07-2017 LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 Gene3D G3DSA:3.40.50.300 62 256 7.6E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 Gene3D G3DSA:3.40.50.300 295 312 7.6E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 SMART SM01086 318 412 1.1E-28 T 06-07-2017 IPR019489 Clp ATPase, C-terminal LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 Pfam PF06689 ClpX C4-type zinc finger 11 48 8.9E-21 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 SUPERFAMILY SSF52540 58 403 1.39E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 SMART SM00994 10 49 1.1E-23 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 SMART SM00382 114 267 1.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS09905 9e825b671a144994991fd529fe0c7016 428 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 416 52.463 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 LK06_RS13030 26ea8119e92226bde35a0e2d6c167831 663 Gene3D G3DSA:3.40.50.980 399 460 1.0E-29 T 06-07-2017 LK06_RS13030 26ea8119e92226bde35a0e2d6c167831 663 Gene3D G3DSA:3.40.50.980 245 343 1.0E-29 T 06-07-2017 LK06_RS13030 26ea8119e92226bde35a0e2d6c167831 663 Gene3D G3DSA:3.40.50.980 79 244 1.3E-30 T 06-07-2017 LK06_RS13030 26ea8119e92226bde35a0e2d6c167831 663 Gene3D G3DSA:3.30.300.30 530 649 6.3E-5 T 06-07-2017 LK06_RS13030 26ea8119e92226bde35a0e2d6c167831 663 SUPERFAMILY SSF56801 71 348 1.07E-105 T 06-07-2017 LK06_RS13030 26ea8119e92226bde35a0e2d6c167831 663 SUPERFAMILY SSF56801 402 662 1.07E-105 T 06-07-2017 LK06_RS13030 26ea8119e92226bde35a0e2d6c167831 663 Pfam PF00501 AMP-binding enzyme 80 532 2.3E-87 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS13030 26ea8119e92226bde35a0e2d6c167831 663 Gene3D G3DSA:2.30.38.10 461 526 5.2E-14 T 06-07-2017 LK06_RS13030 26ea8119e92226bde35a0e2d6c167831 663 ProSitePatterns PS00455 Putative AMP-binding domain signature. 239 250 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS15275 4cf56112bd991e59336b4052828c2aaa 302 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 86 289 3.7E-18 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS15275 4cf56112bd991e59336b4052828c2aaa 302 SUPERFAMILY SSF56219 82 296 1.1E-26 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS15275 4cf56112bd991e59336b4052828c2aaa 302 Gene3D G3DSA:3.60.10.10 82 296 1.5E-15 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS03820 87345478e7020cfce2b41249754782ad 543 Gene3D G3DSA:3.40.50.300 235 485 7.2E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03820 87345478e7020cfce2b41249754782ad 543 SUPERFAMILY SSF52540 250 487 1.82E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15380 f67329d77363b565390601a72cd8ed4a 325 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 2.1E-47 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS15380 f67329d77363b565390601a72cd8ed4a 325 SUPERFAMILY SSF52518 4 183 3.93E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS15380 f67329d77363b565390601a72cd8ed4a 325 SMART SM00861 5 180 7.6E-70 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS15380 f67329d77363b565390601a72cd8ed4a 325 Pfam PF02780 Transketolase, C-terminal domain 195 315 3.4E-38 T 06-07-2017 IPR033248 Transketolase, C-terminal domain LK06_RS15380 f67329d77363b565390601a72cd8ed4a 325 Gene3D G3DSA:3.40.50.920 198 319 4.9E-43 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS15380 f67329d77363b565390601a72cd8ed4a 325 Gene3D G3DSA:3.40.50.970 3 194 3.7E-76 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS15380 f67329d77363b565390601a72cd8ed4a 325 SUPERFAMILY SSF52922 190 323 1.44E-38 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 SUPERFAMILY SSF51905 5 346 2.33E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 Gene3D G3DSA:3.50.50.60 126 338 3.5E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 Gene3D G3DSA:3.50.50.60 5 125 3.1E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 4.6E-22 T 06-07-2017 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 286 4.6E-22 T 06-07-2017 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.6E-22 T 06-07-2017 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 4.6E-22 T 06-07-2017 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 138 4.6E-22 T 06-07-2017 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 Pfam PF04324 BFD-like [2Fe-2S] binding domain 387 435 3.6E-10 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 PIRSF PIRSF037495 1 463 1.9E-136 T 06-07-2017 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 320 3.5E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 123 132 2.3E-14 T 06-07-2017 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 164 189 2.3E-14 T 06-07-2017 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.3E-14 T 06-07-2017 LK06_RS02125 2d60d53d67b94b761ea83b3c1926de2c 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 2.3E-14 T 06-07-2017 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Pfam PF00550 Phosphopantetheine attachment site 921 981 7.8E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Pfam PF00698 Acyl transferase domain 538 822 7.0E-42 T 06-07-2017 IPR014043 Acyl transferase LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Gene3D G3DSA:3.40.366.10 718 827 9.7E-60 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Gene3D G3DSA:3.40.366.10 532 655 9.7E-60 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 540 827 1.6E-72 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 ProSitePatterns PS00012 Phosphopantetheine attachment site. 943 958 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 SUPERFAMILY SSF53901 14 129 1.24E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 SUPERFAMILY SSF53901 160 386 1.24E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 SUPERFAMILY SSF53901 418 439 1.24E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 SUPERFAMILY SSF52151 536 661 1.02E-52 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 SUPERFAMILY SSF52151 720 823 1.02E-52 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Gene3D G3DSA:3.40.47.10 15 276 4.0E-71 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 273 390 1.4E-40 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Gene3D G3DSA:1.10.1200.10 909 982 1.6E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 177 193 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Gene3D G3DSA:3.40.47.10 277 443 1.9E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 SUPERFAMILY SSF47336 912 981 3.53E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 SMART SM00825 Beta-ketoacyl synthase 15 443 1.5E-177 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 SUPERFAMILY SSF55048 660 717 3.92E-6 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 14 264 1.9E-61 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 393 505 2.6E-22 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Pfam PF00975 Thioesterase domain 1008 1241 1.2E-28 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Gene3D G3DSA:3.40.50.1820 993 1111 1.9E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 Gene3D G3DSA:3.40.50.1820 1181 1255 1.9E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS31525 0ec08fe0e8d266c3b6fa25860a83a2c7 1259 SUPERFAMILY SSF53474 990 1254 3.3E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 Gene3D G3DSA:3.50.50.60 2 95 4.7E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 Gene3D G3DSA:3.50.50.60 96 298 1.1E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 230 244 2.8E-7 T 06-07-2017 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 276 2.8E-7 T 06-07-2017 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.8E-7 T 06-07-2017 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 SUPERFAMILY SSF51905 1 301 2.8E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 293 5.5E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 5.2E-23 T 06-07-2017 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 92 110 5.2E-23 T 06-07-2017 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.2E-23 T 06-07-2017 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 5.2E-23 T 06-07-2017 LK06_RS09225 f84ea6c6032c8745adb2fced7d00f0dc 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 5.2E-23 T 06-07-2017 LK06_RS10215 54f7a50031d8fa6993da3e679b82848e 158 Pfam PF00436 Single-strand binding protein family 5 102 2.1E-18 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 LK06_RS10215 54f7a50031d8fa6993da3e679b82848e 158 Gene3D G3DSA:2.40.50.140 4 116 1.1E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS10215 54f7a50031d8fa6993da3e679b82848e 158 SUPERFAMILY SSF50249 5 136 4.9E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 SUPERFAMILY SSF53223 87 236 4.39E-57 T 06-07-2017 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 SMART SM01274 93 226 3.2E-85 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 SMART SM00919 238 465 2.1E-107 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 PIRSF PIRSF000106 66 471 2.5E-83 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 PRINTS PR00072 Malic enzyme signature 265 281 3.1E-11 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 PRINTS PR00072 Malic enzyme signature 155 177 3.1E-11 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 PRINTS PR00072 Malic enzyme signature 358 374 3.1E-11 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 PRINTS PR00072 Malic enzyme signature 234 250 3.1E-11 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 Pfam PF03949 Malic enzyme, NAD binding domain 240 464 5.6E-22 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 Gene3D G3DSA:3.40.50.10380 93 235 1.8E-55 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 Gene3D G3DSA:3.40.50.720 236 464 1.8E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 Gene3D G3DSA:3.30.70.260 12 79 8.6E-4 T 06-07-2017 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 Pfam PF00390 Malic enzyme, N-terminal domain 94 226 6.0E-31 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LK06_RS11440 193a61fe9e856728287f0d0ba6928daa 471 SUPERFAMILY SSF51735 238 469 6.03E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS10270 77bf0a750415c33e4a803e76b199bb45 74 SUPERFAMILY SSF50249 7 73 1.25E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS10270 77bf0a750415c33e4a803e76b199bb45 74 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 1.9E-26 T 06-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 LK06_RS10270 77bf0a750415c33e4a803e76b199bb45 74 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 73 24.738 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 LK06_RS10270 77bf0a750415c33e4a803e76b199bb45 74 Gene3D G3DSA:2.40.50.140 3 73 3.2E-36 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS10270 77bf0a750415c33e4a803e76b199bb45 74 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 8 72 3.3E-34 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 LK06_RS10270 77bf0a750415c33e4a803e76b199bb45 74 SMART SM00316 5 73 2.4E-7 T 06-07-2017 IPR022967 RNA-binding domain, S1 LK06_RS17410 2bcdad25230651d4ce815ecec55bb630 662 SUPERFAMILY SSF101898 528 645 4.45E-23 T 06-07-2017 LK06_RS17410 2bcdad25230651d4ce815ecec55bb630 662 SUPERFAMILY SSF101898 393 501 4.45E-23 T 06-07-2017 LK06_RS17410 2bcdad25230651d4ce815ecec55bb630 662 Gene3D G3DSA:2.120.10.30 373 628 1.5E-24 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like LK06_RS32110 11cace8ac59697a2b9687bfbfa740684 287 SUPERFAMILY SSF51197 65 278 7.78E-30 T 06-07-2017 LK06_RS32110 11cace8ac59697a2b9687bfbfa740684 287 Gene3D G3DSA:3.60.130.10 55 281 4.5E-27 T 06-07-2017 LK06_RS32110 11cace8ac59697a2b9687bfbfa740684 287 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 93 278 2.1E-16 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 LK06_RS24865 422763486eb7cb1d7102709fdcc13c46 500 PIRSF PIRSF017804 15 499 1.1E-140 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD LK06_RS24865 422763486eb7cb1d7102709fdcc13c46 500 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 23 97 5.1E-19 T 06-07-2017 IPR024962 YukD-like LK06_RS24865 422763486eb7cb1d7102709fdcc13c46 500 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 26 495 5.4E-46 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD LK06_RS11475 d928b5eefc03d543824d703fc5055eb1 118 Pfam PF01740 STAS domain 4 89 6.6E-10 T 06-07-2017 IPR002645 STAS domain LK06_RS11475 d928b5eefc03d543824d703fc5055eb1 118 Gene3D G3DSA:3.30.750.24 3 89 7.9E-13 T 06-07-2017 IPR002645 STAS domain LK06_RS11475 d928b5eefc03d543824d703fc5055eb1 118 SUPERFAMILY SSF52091 2 107 1.86E-16 T 06-07-2017 IPR002645 STAS domain LK06_RS21315 cbdeb233cc31644411d91a6e985cd5f6 210 PRINTS PR01021 OMPA domain signature 104 126 7.3E-5 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LK06_RS21315 cbdeb233cc31644411d91a6e985cd5f6 210 PRINTS PR01021 OMPA domain signature 134 149 7.3E-5 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LK06_RS21315 cbdeb233cc31644411d91a6e985cd5f6 210 PRINTS PR01021 OMPA domain signature 149 165 7.3E-5 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LK06_RS21315 cbdeb233cc31644411d91a6e985cd5f6 210 SUPERFAMILY SSF103088 93 205 3.92E-27 T 06-07-2017 IPR006665 OmpA-like domain LK06_RS21315 cbdeb233cc31644411d91a6e985cd5f6 210 Gene3D G3DSA:3.30.1330.60 93 205 5.0E-28 T 06-07-2017 IPR006665 OmpA-like domain LK06_RS21315 cbdeb233cc31644411d91a6e985cd5f6 210 Pfam PF00691 OmpA family 104 199 2.0E-15 T 06-07-2017 IPR006665 OmpA-like domain LK06_RS09435 ef6ac0c76232ed4ae6c2a225b8990c27 118 Pfam PF04237 YjbR 11 102 1.3E-27 T 06-07-2017 IPR007351 Uncharacterised protein YjbR LK06_RS09435 ef6ac0c76232ed4ae6c2a225b8990c27 118 SUPERFAMILY SSF142906 2 115 8.5E-38 T 06-07-2017 LK06_RS00835 3f0ac04962cf176c604e1c23701e075f 383 Pfam PF03824 High-affinity nickel-transport protein 73 362 1.6E-88 T 06-07-2017 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 LK06_RS00835 3f0ac04962cf176c604e1c23701e075f 383 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 76 357 1.1E-120 T 06-07-2017 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 LK06_RS13605 7d8585d8190a79174feda8e005f2b239 291 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 148 2.8E-10 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LK06_RS13605 7d8585d8190a79174feda8e005f2b239 291 Pfam PF00633 Helix-hairpin-helix motif 98 127 7.6E-8 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 LK06_RS13605 7d8585d8190a79174feda8e005f2b239 291 SMART SM00525 191 211 0.0022 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 LK06_RS13605 7d8585d8190a79174feda8e005f2b239 291 ProSitePatterns PS01155 Endonuclease III family signature. 101 130 - T 06-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 LK06_RS13605 7d8585d8190a79174feda8e005f2b239 291 SMART SM00478 38 190 6.8E-32 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LK06_RS13605 7d8585d8190a79174feda8e005f2b239 291 Gene3D G3DSA:1.10.1670.10 122 219 4.6E-34 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 LK06_RS13605 7d8585d8190a79174feda8e005f2b239 291 Gene3D G3DSA:1.10.340.30 21 121 8.2E-34 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS13605 7d8585d8190a79174feda8e005f2b239 291 SUPERFAMILY SSF48150 2 218 3.61E-61 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS30780 16618bfd59b3fd7dfe0e12015864feeb 323 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 142 154 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS30780 16618bfd59b3fd7dfe0e12015864feeb 323 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 29 52 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS30780 16618bfd59b3fd7dfe0e12015864feeb 323 Gene3D G3DSA:1.10.510.10 89 277 1.1E-45 T 06-07-2017 LK06_RS30780 16618bfd59b3fd7dfe0e12015864feeb 323 Pfam PF00069 Protein kinase domain 25 237 8.0E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS30780 16618bfd59b3fd7dfe0e12015864feeb 323 SUPERFAMILY SSF56112 21 288 1.89E-71 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS30780 16618bfd59b3fd7dfe0e12015864feeb 323 SMART SM00220 23 289 8.2E-59 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS30780 16618bfd59b3fd7dfe0e12015864feeb 323 Gene3D G3DSA:3.30.200.20 21 88 3.5E-22 T 06-07-2017 LK06_RS28615 b9517c86dde7766d2f04019a99d5cc98 386 Gene3D G3DSA:3.40.50.10540 12 217 1.4E-99 T 06-07-2017 IPR023606 CoA-transferase family III domain LK06_RS28615 b9517c86dde7766d2f04019a99d5cc98 386 Gene3D G3DSA:3.40.50.10540 302 374 1.4E-99 T 06-07-2017 IPR023606 CoA-transferase family III domain LK06_RS28615 b9517c86dde7766d2f04019a99d5cc98 386 SUPERFAMILY SSF89796 9 375 1.57E-117 T 06-07-2017 IPR023606 CoA-transferase family III domain LK06_RS28615 b9517c86dde7766d2f04019a99d5cc98 386 Gene3D G3DSA:3.30.1540.10 233 301 2.0E-10 T 06-07-2017 LK06_RS28615 b9517c86dde7766d2f04019a99d5cc98 386 Pfam PF02515 CoA-transferase family III 15 364 1.5E-87 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 LK06_RS00020 1b231d075e9724dcbd4b5453f35cc927 339 Pfam PF00155 Aminotransferase class I and II 9 326 2.3E-50 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS00020 1b231d075e9724dcbd4b5453f35cc927 339 Gene3D G3DSA:3.90.1150.10 228 328 4.1E-23 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS00020 1b231d075e9724dcbd4b5453f35cc927 339 Gene3D G3DSA:3.40.640.10 19 227 3.0E-63 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS00020 1b231d075e9724dcbd4b5453f35cc927 339 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 195 204 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 LK06_RS00020 1b231d075e9724dcbd4b5453f35cc927 339 SUPERFAMILY SSF53383 8 329 1.34E-72 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS06195 11ae3db59099865412deb7412516bad2 137 Gene3D G3DSA:3.10.180.10 10 131 1.0E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS06195 11ae3db59099865412deb7412516bad2 137 SUPERFAMILY SSF54593 15 131 3.62E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS06195 11ae3db59099865412deb7412516bad2 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 128 4.3E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS10915 3ddb4c4ba914e9ccb5657ca3d794cefe 353 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 9 347 1.9E-128 T 06-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 LK06_RS10915 3ddb4c4ba914e9ccb5657ca3d794cefe 353 SUPERFAMILY SSF51679 8 346 3.66E-79 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS10915 3ddb4c4ba914e9ccb5657ca3d794cefe 353 Pfam PF00296 Luciferase-like monooxygenase 10 323 5.3E-41 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS10915 3ddb4c4ba914e9ccb5657ca3d794cefe 353 Gene3D G3DSA:3.20.20.30 8 346 3.3E-92 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS02925 e8c1e711b4aec3d4dececf9efe8d275a 293 SUPERFAMILY SSF50891 124 278 6.43E-34 T 06-07-2017 IPR029000 Cyclophilin-like domain LK06_RS02925 e8c1e711b4aec3d4dececf9efe8d275a 293 Gene3D G3DSA:2.40.100.10 124 277 4.4E-33 T 06-07-2017 IPR029000 Cyclophilin-like domain LK06_RS02925 e8c1e711b4aec3d4dececf9efe8d275a 293 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 125 277 2.3E-23 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 LK06_RS24535 dba3feffbb245fb85d71a04a2518703f 533 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 67 243 1.5E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24535 dba3feffbb245fb85d71a04a2518703f 533 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 343 521 9.0E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24535 dba3feffbb245fb85d71a04a2518703f 533 SUPERFAMILY SSF161098 3 248 3.53E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24535 dba3feffbb245fb85d71a04a2518703f 533 Gene3D G3DSA:1.10.3720.10 277 528 6.6E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24535 dba3feffbb245fb85d71a04a2518703f 533 Gene3D G3DSA:1.10.3720.10 4 254 2.1E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24535 dba3feffbb245fb85d71a04a2518703f 533 SUPERFAMILY SSF161098 271 528 1.96E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS22630 52be19f139ff3767f03c886c296da247 337 Pfam PF07728 AAA domain (dynein-related subfamily) 79 233 5.9E-9 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 LK06_RS22630 52be19f139ff3767f03c886c296da247 337 SUPERFAMILY SSF52540 49 294 2.79E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22630 52be19f139ff3767f03c886c296da247 337 SMART SM00382 75 263 6.9E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS22630 52be19f139ff3767f03c886c296da247 337 Gene3D G3DSA:3.40.50.300 51 277 6.0E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20580 2f61b47e7ff86a48fba6e15979afc036 559 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS20580 2f61b47e7ff86a48fba6e15979afc036 559 Gene3D G3DSA:3.30.200.20 9 79 2.9E-19 T 06-07-2017 LK06_RS20580 2f61b47e7ff86a48fba6e15979afc036 559 SUPERFAMILY SSF56112 9 270 9.2E-67 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS20580 2f61b47e7ff86a48fba6e15979afc036 559 SMART SM00220 11 269 5.2E-53 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20580 2f61b47e7ff86a48fba6e15979afc036 559 Pfam PF00069 Protein kinase domain 11 264 9.7E-44 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20580 2f61b47e7ff86a48fba6e15979afc036 559 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS20580 2f61b47e7ff86a48fba6e15979afc036 559 Gene3D G3DSA:1.10.510.10 80 261 2.8E-40 T 06-07-2017 LK06_RS31780 0131533e2ca88b74a42ddcb64d6a375b 425 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 258 370 1.2E-32 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS31780 0131533e2ca88b74a42ddcb64d6a375b 425 Gene3D G3DSA:3.40.47.10 9 260 1.1E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31780 0131533e2ca88b74a42ddcb64d6a375b 425 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9 250 2.9E-44 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS31780 0131533e2ca88b74a42ddcb64d6a375b 425 Gene3D G3DSA:3.40.47.10 266 410 2.0E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31780 0131533e2ca88b74a42ddcb64d6a375b 425 SUPERFAMILY SSF53901 8 255 2.41E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31780 0131533e2ca88b74a42ddcb64d6a375b 425 SMART SM00825 Beta-ketoacyl synthase 8 403 2.8E-13 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS31780 0131533e2ca88b74a42ddcb64d6a375b 425 SUPERFAMILY SSF53901 218 411 2.37E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31780 0131533e2ca88b74a42ddcb64d6a375b 425 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 158 174 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 Pfam PF05593 RHS Repeat 877 910 4.0E-5 T 06-07-2017 IPR031325 RHS repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 Pfam PF05593 RHS Repeat 625 662 1.1E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 Pfam PF05593 RHS Repeat 455 491 2.7E-6 T 06-07-2017 IPR031325 RHS repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 Pfam PF05593 RHS Repeat 1092 1124 2.3E-5 T 06-07-2017 IPR031325 RHS repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 Pfam PF05593 RHS Repeat 689 746 1.2E-6 T 06-07-2017 IPR031325 RHS repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 Pfam PF05593 RHS Repeat 604 640 5.2E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 Pfam PF05593 RHS Repeat 772 809 1.9E-9 T 06-07-2017 IPR031325 RHS repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 Pfam PF05593 RHS Repeat 667 702 7.4E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 Pfam PF05593 RHS Repeat 561 599 3.6E-6 T 06-07-2017 IPR031325 RHS repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 SUPERFAMILY SSF69304 1058 1170 8.11E-10 T 06-07-2017 LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 SUPERFAMILY SSF69304 762 849 8.11E-10 T 06-07-2017 LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 SUPERFAMILY SSF69304 887 938 8.11E-10 T 06-07-2017 LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 604 645 1.1E-6 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 721 748 6.8E-5 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 917 947 8.6E-4 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 772 812 1.3E-10 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 647 685 1.3E-7 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 814 855 0.001 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 440 467 0.0012 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 519 560 2.5E-5 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 567 597 4.1E-4 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 689 728 5.7E-4 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 455 490 6.0E-8 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 540 565 2.8E-5 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 476 505 0.0028 T 06-07-2017 IPR006530 YD repeat LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1227 1303 8.7E-18 T 06-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 LK06_RS14225 156485faabdd2f983769235c2399ea08 1420 SUPERFAMILY SSF101898 524 743 3.14E-6 T 06-07-2017 LK06_RS04370 2621eed840412f41780dbfc0f541871b 241 Pfam PF00929 Exonuclease 11 179 7.3E-14 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III LK06_RS04370 2621eed840412f41780dbfc0f541871b 241 SUPERFAMILY SSF53098 4 200 1.68E-39 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS04370 2621eed840412f41780dbfc0f541871b 241 Gene3D G3DSA:3.30.420.10 3 188 1.3E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS04370 2621eed840412f41780dbfc0f541871b 241 SMART SM00479 8 189 1.4E-21 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III LK06_RS09845 01d59005025b5a26971bd6460550e952 653 Gene3D G3DSA:3.80.30.20 263 492 4.3E-44 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe LK06_RS09845 01d59005025b5a26971bd6460550e952 653 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 12 618 9.0E-214 T 06-07-2017 IPR023862 Conserved hypothetical protein CHP03960, radical SAM LK06_RS09845 01d59005025b5a26971bd6460550e952 653 SUPERFAMILY SSF102114 232 635 3.92E-51 T 06-07-2017 LK06_RS09845 01d59005025b5a26971bd6460550e952 653 SMART SM00729 264 487 7.9E-29 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS09845 01d59005025b5a26971bd6460550e952 653 Pfam PF04055 Radical SAM superfamily 268 433 4.1E-15 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS05900 88661d2d855e3e1a24ff61b51eff43c8 265 SUPERFAMILY SSF52540 4 232 1.95E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05900 88661d2d855e3e1a24ff61b51eff43c8 265 Pfam PF00005 ABC transporter 21 173 2.5E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS05900 88661d2d855e3e1a24ff61b51eff43c8 265 Gene3D G3DSA:3.40.50.300 2 232 2.6E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05900 88661d2d855e3e1a24ff61b51eff43c8 265 SMART SM00382 29 224 6.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS10135 410e4802d4088b5a3a315da86fc6d33e 342 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 14 306 6.1E-19 T 06-07-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 LK06_RS10135 410e4802d4088b5a3a315da86fc6d33e 342 SUPERFAMILY SSF53067 122 312 6.76E-32 T 06-07-2017 LK06_RS10135 410e4802d4088b5a3a315da86fc6d33e 342 SUPERFAMILY SSF53067 11 116 1.84E-14 T 06-07-2017 LK06_RS10135 410e4802d4088b5a3a315da86fc6d33e 342 Gene3D G3DSA:3.30.420.40 182 297 5.0E-5 T 06-07-2017 LK06_RS24245 201ec27b0be840425f718d84ed3869db 61 Gene3D G3DSA:4.10.1160.10 19 61 1.7E-23 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24245 201ec27b0be840425f718d84ed3869db 61 SUPERFAMILY SSF143800 2 59 2.55E-23 T 06-07-2017 LK06_RS24245 201ec27b0be840425f718d84ed3869db 61 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 61 17.092 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24245 201ec27b0be840425f718d84ed3869db 61 Pfam PF00830 Ribosomal L28 family 4 58 3.3E-24 T 06-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24245 201ec27b0be840425f718d84ed3869db 61 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 56 1.3E-23 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS25905 dea9557a0f6b4a85e4c8c16e3bdc5868 644 Pfam PF00733 Asparagine synthase 242 630 1.3E-92 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 LK06_RS25905 dea9557a0f6b4a85e4c8c16e3bdc5868 644 SUPERFAMILY SSF56235 1 223 7.03E-62 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS25905 dea9557a0f6b4a85e4c8c16e3bdc5868 644 Gene3D G3DSA:3.40.50.620 222 383 1.9E-76 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS25905 dea9557a0f6b4a85e4c8c16e3bdc5868 644 Gene3D G3DSA:3.40.50.620 480 630 1.9E-76 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS25905 dea9557a0f6b4a85e4c8c16e3bdc5868 644 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 563 1.2E-126 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 LK06_RS25905 dea9557a0f6b4a85e4c8c16e3bdc5868 644 Gene3D G3DSA:3.60.20.10 17 221 6.5E-78 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS25905 dea9557a0f6b4a85e4c8c16e3bdc5868 644 PIRSF PIRSF001589 1 643 5.8E-151 T 06-07-2017 LK06_RS25905 dea9557a0f6b4a85e4c8c16e3bdc5868 644 SUPERFAMILY SSF52402 242 387 1.02E-69 T 06-07-2017 LK06_RS25905 dea9557a0f6b4a85e4c8c16e3bdc5868 644 SUPERFAMILY SSF52402 485 624 1.02E-69 T 06-07-2017 LK06_RS25905 dea9557a0f6b4a85e4c8c16e3bdc5868 644 Pfam PF13537 Glutamine amidotransferase domain 48 165 2.3E-43 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain LK06_RS24325 fab722fffe6051f75a2b80e3f9c7cc92 93 Pfam PF00708 Acylphosphatase 6 93 1.9E-20 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LK06_RS24325 fab722fffe6051f75a2b80e3f9c7cc92 93 SUPERFAMILY SSF54975 4 93 1.07E-22 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LK06_RS24325 fab722fffe6051f75a2b80e3f9c7cc92 93 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LK06_RS24325 fab722fffe6051f75a2b80e3f9c7cc92 93 Gene3D G3DSA:3.30.70.100 5 93 4.3E-25 T 06-07-2017 LK06_RS28520 e4c276da63c599ec82cac2cd5bd507ef 204 Pfam PF16859 Bacterial transcriptional repressor C-terminal 86 196 1.7E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS28520 e4c276da63c599ec82cac2cd5bd507ef 204 SUPERFAMILY SSF46689 17 80 1.2E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS28520 e4c276da63c599ec82cac2cd5bd507ef 204 Gene3D G3DSA:1.10.357.10 71 200 1.1E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS28520 e4c276da63c599ec82cac2cd5bd507ef 204 SUPERFAMILY SSF48498 89 199 4.71E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS28520 e4c276da63c599ec82cac2cd5bd507ef 204 Gene3D G3DSA:1.10.10.60 15 70 8.6E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS28520 e4c276da63c599ec82cac2cd5bd507ef 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 1.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS03580 9a67f5888323122e154e760758ed4a98 176 PRINTS PR01438 Universal stress protein signature 9 27 6.8E-5 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS03580 9a67f5888323122e154e760758ed4a98 176 PRINTS PR01438 Universal stress protein signature 111 123 6.8E-5 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS03580 9a67f5888323122e154e760758ed4a98 176 PRINTS PR01438 Universal stress protein signature 128 150 6.8E-5 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS03580 9a67f5888323122e154e760758ed4a98 176 Pfam PF00582 Universal stress protein family 11 150 3.2E-19 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS03580 9a67f5888323122e154e760758ed4a98 176 Gene3D G3DSA:3.40.50.620 9 152 7.6E-24 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS03580 9a67f5888323122e154e760758ed4a98 176 SUPERFAMILY SSF52402 11 153 4.94E-23 T 06-07-2017 LK06_RS14885 bdb3addbc45258a23884a9a9cef9ce12 510 SMART SM00487 96 296 1.2E-52 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS14885 bdb3addbc45258a23884a9a9cef9ce12 510 Pfam PF00270 DEAD/DEAH box helicase 101 268 2.9E-44 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS14885 bdb3addbc45258a23884a9a9cef9ce12 510 SMART SM00490 330 411 6.0E-29 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS14885 bdb3addbc45258a23884a9a9cef9ce12 510 SUPERFAMILY SSF52540 148 426 1.4E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14885 bdb3addbc45258a23884a9a9cef9ce12 510 Gene3D G3DSA:3.40.50.300 286 444 2.9E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14885 bdb3addbc45258a23884a9a9cef9ce12 510 Pfam PF00271 Helicase conserved C-terminal domain 313 411 7.2E-24 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS14885 bdb3addbc45258a23884a9a9cef9ce12 510 Gene3D G3DSA:3.40.50.300 73 285 5.1E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30750 ea4866db243d58da0e32f8ecbff17c3d 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS30750 ea4866db243d58da0e32f8ecbff17c3d 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS30750 ea4866db243d58da0e32f8ecbff17c3d 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS30750 ea4866db243d58da0e32f8ecbff17c3d 304 Gene3D G3DSA:1.10.10.10 1 86 1.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30750 ea4866db243d58da0e32f8ecbff17c3d 304 Gene3D G3DSA:3.40.190.10 174 260 1.2E-19 T 06-07-2017 LK06_RS30750 ea4866db243d58da0e32f8ecbff17c3d 304 Gene3D G3DSA:3.40.190.10 90 173 8.0E-17 T 06-07-2017 LK06_RS30750 ea4866db243d58da0e32f8ecbff17c3d 304 Pfam PF03466 LysR substrate binding domain 88 291 2.6E-45 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS30750 ea4866db243d58da0e32f8ecbff17c3d 304 SUPERFAMILY SSF46785 1 85 3.71E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30750 ea4866db243d58da0e32f8ecbff17c3d 304 SUPERFAMILY SSF53850 89 292 5.43E-41 T 06-07-2017 LK06_RS30750 ea4866db243d58da0e32f8ecbff17c3d 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.4E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS24540 35998b7ab209e7d27468e0f90653693f 339 Pfam PF00005 ABC transporter 18 160 4.5E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS24540 35998b7ab209e7d27468e0f90653693f 339 SMART SM00382 27 210 4.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS24540 35998b7ab209e7d27468e0f90653693f 339 SUPERFAMILY SSF50331 237 339 4.25E-7 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal LK06_RS24540 35998b7ab209e7d27468e0f90653693f 339 Gene3D G3DSA:3.40.50.300 2 233 2.4E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24540 35998b7ab209e7d27468e0f90653693f 339 Pfam PF08402 TOBE domain 268 338 1.0E-9 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 LK06_RS24540 35998b7ab209e7d27468e0f90653693f 339 SUPERFAMILY SSF52540 3 240 2.49E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24540 35998b7ab209e7d27468e0f90653693f 339 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 60 254 8.4E-37 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 Pfam PF00717 Peptidase S24-like 81 184 2.4E-15 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 ProSitePatterns PS00761 Signal peptidases I signature 3. 213 226 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 159 171 8.9E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 208 227 8.9E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 74 90 8.9E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 SUPERFAMILY SSF51306 73 121 1.67E-46 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 SUPERFAMILY SSF51306 154 260 1.67E-46 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 Gene3D G3DSA:2.10.109.10 208 266 2.8E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 Gene3D G3DSA:2.10.109.10 153 169 2.8E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS24440 a988ac5a49ea818074a73688262fdafe 363 Gene3D G3DSA:2.10.109.10 71 120 2.8E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS16310 ffed3e48fe3e93a90630ef8ece2b23bd 321 SUPERFAMILY SSF103642 24 43 1.06E-6 T 06-07-2017 LK06_RS16310 ffed3e48fe3e93a90630ef8ece2b23bd 321 Pfam PF02810 SEC-C motif 27 43 5.4E-8 T 06-07-2017 IPR004027 SEC-C motif LK06_RS16310 ffed3e48fe3e93a90630ef8ece2b23bd 321 Gene3D G3DSA:3.10.450.50 7 43 1.5E-8 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS01335 f0bea5c7bef8317b3567223f48cc935e 321 SUPERFAMILY SSF51182 35 302 6.08E-67 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS01335 f0bea5c7bef8317b3567223f48cc935e 321 Pfam PF05726 Pirin C-terminal cupin domain 193 292 3.9E-19 T 06-07-2017 IPR008778 Pirin, C-terminal domain LK06_RS01335 f0bea5c7bef8317b3567223f48cc935e 321 PIRSF PIRSF006232 20 301 1.6E-78 T 06-07-2017 IPR012093 Pirin LK06_RS01335 f0bea5c7bef8317b3567223f48cc935e 321 Gene3D G3DSA:2.60.120.10 27 265 1.4E-57 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS01335 f0bea5c7bef8317b3567223f48cc935e 321 Pfam PF02678 Pirin 41 141 1.4E-23 T 06-07-2017 IPR003829 Pirin, N-terminal domain LK06_RS26825 9b3fdeb49d5819929f46a16628e7f7f9 720 SUPERFAMILY SSF48576 377 697 2.88E-60 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS26825 9b3fdeb49d5819929f46a16628e7f7f9 720 SUPERFAMILY SSF48576 3 331 5.47E-68 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS26825 9b3fdeb49d5819929f46a16628e7f7f9 720 Gene3D G3DSA:1.10.600.10 5 323 8.2E-106 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS26825 9b3fdeb49d5819929f46a16628e7f7f9 720 Gene3D G3DSA:1.10.600.10 377 690 3.7E-89 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS11435 6b744b231765a492346ee832a88627a9 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.7E-28 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 LK06_RS11435 6b744b231765a492346ee832a88627a9 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 LK06_RS11435 6b744b231765a492346ee832a88627a9 93 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 3.2E-8 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 LK06_RS11435 6b744b231765a492346ee832a88627a9 93 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 3.2E-8 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 LK06_RS11435 6b744b231765a492346ee832a88627a9 93 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 3.2E-8 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 LK06_RS11435 6b744b231765a492346ee832a88627a9 93 SUPERFAMILY SSF47729 1 91 8.68E-27 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 LK06_RS11435 6b744b231765a492346ee832a88627a9 93 SMART SM00411 1 91 4.3E-39 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 LK06_RS11435 6b744b231765a492346ee832a88627a9 93 Gene3D G3DSA:4.10.520.10 1 91 2.3E-29 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 LK06_RS08965 8fb1e8096c4b3cc9e6238fa521fde196 324 SUPERFAMILY SSF53474 17 262 2.22E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08965 8fb1e8096c4b3cc9e6238fa521fde196 324 Gene3D G3DSA:3.40.50.1820 25 262 2.8E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08965 8fb1e8096c4b3cc9e6238fa521fde196 324 Pfam PF12697 Alpha/beta hydrolase family 53 311 1.8E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 6 470 2.9E-201 T 06-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 SUPERFAMILY SSF51735 5 175 3.63E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 256 268 - T 06-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 Gene3D G3DSA:3.40.50.720 2 182 9.9E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 SMART SM01350 181 471 1.1E-197 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 SUPERFAMILY SSF48179 179 473 1.74E-115 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 176 1.0E-49 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 252 279 1.4E-80 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 121 146 1.4E-80 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 5 28 1.4E-80 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 360 382 1.4E-80 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 68 97 1.4E-80 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 170 198 1.4E-80 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 181 470 3.3E-119 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 Gene3D G3DSA:1.10.1040.10 183 437 3.3E-102 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 PIRSF PIRSF000109 1 479 1.2E-197 T 06-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS01775 ece6376cd945bc32e4d1c57c31422937 479 Gene3D G3DSA:1.20.5.320 439 478 1.7E-19 T 06-07-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS20200 aaa32d162f0d5382ed35a2f89d475f32 601 Pfam PF00069 Protein kinase domain 15 262 8.1E-50 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20200 aaa32d162f0d5382ed35a2f89d475f32 601 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS20200 aaa32d162f0d5382ed35a2f89d475f32 601 SMART SM00220 15 274 5.5E-68 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20200 aaa32d162f0d5382ed35a2f89d475f32 601 Gene3D G3DSA:3.30.200.20 10 84 2.1E-25 T 06-07-2017 LK06_RS20200 aaa32d162f0d5382ed35a2f89d475f32 601 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS20200 aaa32d162f0d5382ed35a2f89d475f32 601 Gene3D G3DSA:1.10.510.10 85 270 4.0E-48 T 06-07-2017 LK06_RS20200 aaa32d162f0d5382ed35a2f89d475f32 601 SUPERFAMILY SSF56112 8 281 1.35E-70 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS29765 2669ce7dc09d9d54745bcf00a78ad923 721 SUPERFAMILY SSF55874 634 707 9.03E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS29765 2669ce7dc09d9d54745bcf00a78ad923 721 Pfam PF08448 PAS fold 66 149 2.0E-8 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS29765 2669ce7dc09d9d54745bcf00a78ad923 721 SUPERFAMILY SSF55785 62 150 1.33E-8 T 06-07-2017 IPR000014 PAS domain LK06_RS29765 2669ce7dc09d9d54745bcf00a78ad923 721 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 396 594 1.4E-43 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS29765 2669ce7dc09d9d54745bcf00a78ad923 721 Pfam PF13581 Histidine kinase-like ATPase domain 609 703 8.9E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS29765 2669ce7dc09d9d54745bcf00a78ad923 721 Gene3D G3DSA:3.30.450.20 64 152 9.6E-8 T 06-07-2017 LK06_RS29765 2669ce7dc09d9d54745bcf00a78ad923 721 SMART SM00331 369 594 4.0E-29 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS29765 2669ce7dc09d9d54745bcf00a78ad923 721 Gene3D G3DSA:3.30.450.40 165 347 2.1E-7 T 06-07-2017 IPR029016 GAF domain-like LK06_RS29765 2669ce7dc09d9d54745bcf00a78ad923 721 SUPERFAMILY SSF81606 386 593 5.89E-11 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS00070 9e63729fe9676e0e212d927b4e7837d8 133 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS00070 9e63729fe9676e0e212d927b4e7837d8 133 SUPERFAMILY SSF46955 1 118 5.86E-28 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS00070 9e63729fe9676e0e212d927b4e7837d8 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 6.2E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS00070 9e63729fe9676e0e212d927b4e7837d8 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.2E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS00070 9e63729fe9676e0e212d927b4e7837d8 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.2E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS00070 9e63729fe9676e0e212d927b4e7837d8 133 SMART SM00422 1 70 6.6E-32 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS00070 9e63729fe9676e0e212d927b4e7837d8 133 Gene3D G3DSA:1.10.1660.10 55 124 3.0E-11 T 06-07-2017 LK06_RS00070 9e63729fe9676e0e212d927b4e7837d8 133 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.0E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS00070 9e63729fe9676e0e212d927b4e7837d8 133 Gene3D G3DSA:1.10.1660.10 1 54 2.3E-25 T 06-07-2017 LK06_RS00150 3fb2733e8131c0fe21b18d9278e5767d 131 Pfam PF13466 STAS domain 32 110 2.1E-15 T 06-07-2017 IPR002645 STAS domain LK06_RS00150 3fb2733e8131c0fe21b18d9278e5767d 131 Gene3D G3DSA:3.30.750.24 23 120 7.7E-24 T 06-07-2017 IPR002645 STAS domain LK06_RS00150 3fb2733e8131c0fe21b18d9278e5767d 131 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 25 118 8.0E-20 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 LK06_RS00150 3fb2733e8131c0fe21b18d9278e5767d 131 SUPERFAMILY SSF52091 25 119 9.81E-20 T 06-07-2017 IPR002645 STAS domain LK06_RS08575 ac32be8d47c9539204ccd298bbf3c575 409 SUPERFAMILY SSF48239 38 204 1.05E-21 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS08575 ac32be8d47c9539204ccd298bbf3c575 409 Gene3D G3DSA:1.50.10.20 40 222 7.9E-20 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS08575 ac32be8d47c9539204ccd298bbf3c575 409 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 71 120 2.3 T 06-07-2017 IPR001330 PFTB repeat GO:0003824 LK06_RS08575 ac32be8d47c9539204ccd298bbf3c575 409 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 126 167 1.0E-9 T 06-07-2017 IPR001330 PFTB repeat GO:0003824 LK06_RS06770 cb156f2b83f33d5fab4c4ca4463c05d1 84 Pfam PF04149 Domain of unknown function (DUF397) 23 75 6.4E-14 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS29670 3a38c84205d3280f034bc31aa49fce15 856 SMART SM00487 46 227 2.2E-17 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS29670 3a38c84205d3280f034bc31aa49fce15 856 Pfam PF00271 Helicase conserved C-terminal domain 300 382 6.6E-6 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS29670 3a38c84205d3280f034bc31aa49fce15 856 Pfam PF00270 DEAD/DEAH box helicase 52 197 5.5E-11 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS29670 3a38c84205d3280f034bc31aa49fce15 856 SMART SM00490 296 382 1.1E-12 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS29670 3a38c84205d3280f034bc31aa49fce15 856 Gene3D G3DSA:3.40.50.300 235 396 4.3E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29670 3a38c84205d3280f034bc31aa49fce15 856 SUPERFAMILY SSF52540 302 394 4.68E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29670 3a38c84205d3280f034bc31aa49fce15 856 SUPERFAMILY SSF52540 63 269 4.68E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29670 3a38c84205d3280f034bc31aa49fce15 856 Pfam PF12029 Domain of unknown function (DUF3516) 393 853 2.8E-219 T 06-07-2017 IPR021904 Protein of unknown function DUF3516 LK06_RS29670 3a38c84205d3280f034bc31aa49fce15 856 Gene3D G3DSA:3.40.50.300 37 211 3.7E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28100 97a403c4f86d0fac80471932bcb95398 218 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 LK06_RS28100 97a403c4f86d0fac80471932bcb95398 218 SMART SM00855 2 157 1.2E-16 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS28100 97a403c4f86d0fac80471932bcb95398 218 Gene3D G3DSA:3.40.50.1240 1 189 2.2E-34 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS28100 97a403c4f86d0fac80471932bcb95398 218 SUPERFAMILY SSF53254 1 197 1.22E-36 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS28100 97a403c4f86d0fac80471932bcb95398 218 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 196 4.0E-39 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 PIRSF PIRSF000429 1 406 2.5E-130 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 8.4E-141 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 1.3E-60 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 Gene3D G3DSA:3.40.47.10 171 209 3.9E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 Gene3D G3DSA:3.40.47.10 289 404 3.9E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 SUPERFAMILY SSF53901 283 404 3.93E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 Pfam PF02803 Thiolase, C-terminal domain 282 404 1.4E-48 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 Gene3D G3DSA:3.40.47.10 4 125 7.6E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 Gene3D G3DSA:3.40.47.10 210 288 7.6E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS20025 264b609f5bf369f50e6c3c6a7299e26f 406 SUPERFAMILY SSF53901 3 282 5.76E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 7 827 0.0 T 06-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 SUPERFAMILY SSF55486 199 449 7.81E-71 T 06-07-2017 LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 Gene3D G3DSA:1.10.390.10 303 449 2.6E-40 T 06-07-2017 LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 Pfam PF11838 ERAP1-like C-terminal domain 512 822 4.3E-49 T 06-07-2017 IPR024571 ERAP1-like C-terminal domain LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 SUPERFAMILY SSF63737 5 192 1.09E-36 T 06-07-2017 LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 256 266 2.6E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 309 321 2.6E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 290 305 2.6E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 2.6E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 132 147 2.6E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS06955 e23070ef1e42f2ffc863ab4994c6369f 861 Pfam PF01433 Peptidase family M1 22 383 5.7E-67 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS22695 fc3df0ff9abfeb43c261529b6b22f229 163 SUPERFAMILY SSF46785 26 162 2.16E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22695 fc3df0ff9abfeb43c261529b6b22f229 163 SMART SM00347 47 147 1.6E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS22695 fc3df0ff9abfeb43c261529b6b22f229 163 Pfam PF01047 MarR family 57 111 6.4E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS22695 fc3df0ff9abfeb43c261529b6b22f229 163 Gene3D G3DSA:1.10.10.10 16 161 1.3E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22695 fc3df0ff9abfeb43c261529b6b22f229 163 ProSitePatterns PS01117 MarR-type HTH domain signature. 86 120 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site LK06_RS31710 df457251a8b1b41127fafc1d933a765f 310 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 220 309 2.2E-14 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS31710 df457251a8b1b41127fafc1d933a765f 310 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 183 8.4E-5 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS31710 df457251a8b1b41127fafc1d933a765f 310 SUPERFAMILY SSF53901 6 309 1.35E-26 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31710 df457251a8b1b41127fafc1d933a765f 310 Gene3D G3DSA:3.40.47.10 3 166 1.9E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31710 df457251a8b1b41127fafc1d933a765f 310 Gene3D G3DSA:3.40.47.10 167 309 6.6E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18605 96130211b585824a34cdbea55973c281 372 Pfam PF00266 Aminotransferase class-V 18 331 1.2E-21 T 06-07-2017 IPR000192 Aminotransferase class V domain LK06_RS18605 96130211b585824a34cdbea55973c281 372 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 372 23.648 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 LK06_RS18605 96130211b585824a34cdbea55973c281 372 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 11 372 1.2E-217 T 06-07-2017 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 LK06_RS18605 96130211b585824a34cdbea55973c281 372 Gene3D G3DSA:3.90.1150.10 268 370 5.6E-4 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS18605 96130211b585824a34cdbea55973c281 372 PIRSF PIRSF000525 1 372 4.0E-77 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 LK06_RS18605 96130211b585824a34cdbea55973c281 372 Gene3D G3DSA:3.40.640.10 20 266 8.7E-52 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS18605 96130211b585824a34cdbea55973c281 372 SUPERFAMILY SSF53383 12 370 2.96E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS07500 408da76f0b5f1a07243259a53efb5b11 259 SMART SM00563 33 154 5.2E-34 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS07500 408da76f0b5f1a07243259a53efb5b11 259 SUPERFAMILY SSF69593 7 222 1.57E-50 T 06-07-2017 LK06_RS07500 408da76f0b5f1a07243259a53efb5b11 259 Gene3D G3DSA:3.40.1130.10 17 207 3.4E-32 T 06-07-2017 LK06_RS07500 408da76f0b5f1a07243259a53efb5b11 259 Pfam PF01553 Acyltransferase 21 151 2.9E-21 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS13375 404c7f935901368080650a6d4f613ff3 341 Pfam PF08279 HTH domain 7 62 2.2E-13 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 LK06_RS13375 404c7f935901368080650a6d4f613ff3 341 Gene3D G3DSA:1.10.10.10 3 65 1.1E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13375 404c7f935901368080650a6d4f613ff3 341 SUPERFAMILY SSF46785 5 61 3.82E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13375 404c7f935901368080650a6d4f613ff3 341 Pfam PF13280 WYL domain 143 311 2.6E-23 T 06-07-2017 IPR026881 WYL domain LK06_RS13375 404c7f935901368080650a6d4f613ff3 341 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 LK06_RS13375 404c7f935901368080650a6d4f613ff3 341 SMART SM00420 7 53 0.006 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 Pfam PF00732 GMC oxidoreductase 8 293 2.4E-60 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 SUPERFAMILY SSF54373 287 451 3.04E-38 T 06-07-2017 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 251 265 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 Pfam PF05199 GMC oxidoreductase 364 503 5.7E-38 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.9E-5 T 06-07-2017 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 493 508 1.9E-5 T 06-07-2017 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 Gene3D G3DSA:3.50.50.60 5 128 3.4E-105 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 Gene3D G3DSA:3.50.50.60 444 508 3.4E-105 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 Gene3D G3DSA:3.50.50.60 180 310 3.4E-105 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 SUPERFAMILY SSF51905 447 509 6.36E-70 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20415 f22ba9923b316183a71f349d5b45cf98 516 SUPERFAMILY SSF51905 5 280 6.36E-70 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS24975 5fc13282ce76d67707768e9470b9b5da 927 Pfam PF01580 FtsK/SpoIIIE family 550 748 1.1E-55 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS24975 5fc13282ce76d67707768e9470b9b5da 927 SUPERFAMILY SSF52540 521 820 2.78E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24975 5fc13282ce76d67707768e9470b9b5da 927 Pfam PF09397 Ftsk gamma domain 852 909 1.3E-21 T 06-07-2017 IPR018541 FtsK gamma domain LK06_RS24975 5fc13282ce76d67707768e9470b9b5da 927 SMART SM00382 583 781 1.9E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS24975 5fc13282ce76d67707768e9470b9b5da 927 SUPERFAMILY SSF46785 849 914 5.17E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS24975 5fc13282ce76d67707768e9470b9b5da 927 Gene3D G3DSA:3.40.50.300 522 815 3.9E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24975 5fc13282ce76d67707768e9470b9b5da 927 SMART SM00843 848 912 1.6E-28 T 06-07-2017 IPR018541 FtsK gamma domain LK06_RS20730 f4bb340304382a7a36dd7e869885e376 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 30 87 2.7E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS20730 f4bb340304382a7a36dd7e869885e376 319 SUPERFAMILY SSF53850 114 317 3.14E-43 T 06-07-2017 LK06_RS20730 f4bb340304382a7a36dd7e869885e376 319 Gene3D G3DSA:3.40.190.10 201 288 8.3E-31 T 06-07-2017 LK06_RS20730 f4bb340304382a7a36dd7e869885e376 319 Gene3D G3DSA:3.40.190.10 115 200 5.8E-21 T 06-07-2017 LK06_RS20730 f4bb340304382a7a36dd7e869885e376 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 64 75 3.6E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS20730 f4bb340304382a7a36dd7e869885e376 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.6E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS20730 f4bb340304382a7a36dd7e869885e376 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 64 3.6E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS20730 f4bb340304382a7a36dd7e869885e376 319 Gene3D G3DSA:1.10.10.10 30 110 2.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20730 f4bb340304382a7a36dd7e869885e376 319 Pfam PF03466 LysR substrate binding domain 113 313 3.2E-49 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS20730 f4bb340304382a7a36dd7e869885e376 319 SUPERFAMILY SSF46785 31 109 9.35E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00175 c578ac7947723ee8fa36647396ff5318 290 PRINTS PR01438 Universal stress protein signature 2 20 6.5E-13 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00175 c578ac7947723ee8fa36647396ff5318 290 PRINTS PR01438 Universal stress protein signature 99 111 6.5E-13 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00175 c578ac7947723ee8fa36647396ff5318 290 PRINTS PR01438 Universal stress protein signature 117 139 6.5E-13 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00175 c578ac7947723ee8fa36647396ff5318 290 SUPERFAMILY SSF52402 153 289 2.51E-23 T 06-07-2017 LK06_RS00175 c578ac7947723ee8fa36647396ff5318 290 Gene3D G3DSA:3.40.50.620 4 139 1.4E-29 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS00175 c578ac7947723ee8fa36647396ff5318 290 Gene3D G3DSA:3.40.50.620 150 287 5.0E-25 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS00175 c578ac7947723ee8fa36647396ff5318 290 Pfam PF00582 Universal stress protein family 5 139 7.1E-23 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS00175 c578ac7947723ee8fa36647396ff5318 290 Pfam PF00582 Universal stress protein family 152 287 1.9E-18 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS00175 c578ac7947723ee8fa36647396ff5318 290 SUPERFAMILY SSF52402 4 141 7.37E-27 T 06-07-2017 LK06_RS08620 13709d6d3f783cf2464e92fa2b350334 679 Pfam PF14378 PAP2 superfamily 467 647 8.3E-47 T 06-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 LK06_RS08620 13709d6d3f783cf2464e92fa2b350334 679 Pfam PF09594 Protein of unknown function (DUF2029) 79 314 8.3E-32 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 LK06_RS18615 461ec0f7f8c1185a199d06fbb1b605a4 373 Pfam PF02388 FemAB family 268 366 7.3E-18 T 06-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 LK06_RS18615 461ec0f7f8c1185a199d06fbb1b605a4 373 Pfam PF02388 FemAB family 8 250 9.0E-30 T 06-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 LK06_RS18615 461ec0f7f8c1185a199d06fbb1b605a4 373 Gene3D G3DSA:3.40.630.30 186 346 7.0E-53 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS18615 461ec0f7f8c1185a199d06fbb1b605a4 373 Gene3D G3DSA:3.40.630.30 2 116 7.9E-52 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS18615 461ec0f7f8c1185a199d06fbb1b605a4 373 Gene3D G3DSA:3.40.630.30 148 185 7.9E-52 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS18615 461ec0f7f8c1185a199d06fbb1b605a4 373 SUPERFAMILY SSF55729 184 366 1.06E-41 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS18615 461ec0f7f8c1185a199d06fbb1b605a4 373 SUPERFAMILY SSF55729 143 188 4.24E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS18615 461ec0f7f8c1185a199d06fbb1b605a4 373 SUPERFAMILY SSF55729 3 114 4.24E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS31505 7e839d06a30e1ae48fe3c5315e766ce5 339 Gene3D G3DSA:1.20.1260.10 38 302 2.4E-92 T 06-07-2017 IPR012347 Ferritin-related LK06_RS31505 7e839d06a30e1ae48fe3c5315e766ce5 339 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 28 329 3.6E-128 T 06-07-2017 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 LK06_RS31505 7e839d06a30e1ae48fe3c5315e766ce5 339 SUPERFAMILY SSF47240 48 298 2.07E-70 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS31505 7e839d06a30e1ae48fe3c5315e766ce5 339 Pfam PF05138 Phenylacetic acid catabolic protein 38 325 1.1E-94 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 SUPERFAMILY SSF55486 216 460 5.42E-72 T 06-07-2017 LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 Pfam PF11838 ERAP1-like C-terminal domain 535 846 6.3E-60 T 06-07-2017 IPR024571 ERAP1-like C-terminal domain LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 852 0.0 T 06-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 SUPERFAMILY SSF63737 8 198 5.89E-36 T 06-07-2017 LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 Pfam PF01433 Peptidase family M1 39 395 5.5E-63 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 139 154 4.2E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 181 196 4.2E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 269 279 4.2E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 303 318 4.2E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 322 334 4.2E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS10005 197a9e5eef30575064dd9457177d788f 860 Gene3D G3DSA:1.10.390.10 316 462 1.3E-39 T 06-07-2017 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 518 6.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 532 6.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 576 6.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 557 6.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 SMART SM00388 355 422 6.1E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 SUPERFAMILY SSF55874 412 581 9.43E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 SMART SM00387 468 579 9.0E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 SUPERFAMILY SSF158472 295 343 1.7E-7 T 06-07-2017 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 Pfam PF00672 HAMP domain 276 343 3.4E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 Pfam PF00512 His Kinase A (phospho-acceptor) domain 355 422 5.1E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 Gene3D G3DSA:3.30.565.10 425 580 1.2E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 Gene3D G3DSA:1.10.287.130 346 418 6.4E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 SUPERFAMILY SSF47384 338 422 7.85E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 578 1.0E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11765 b4dde746195218497ec394b984eb27e9 704 SMART SM00304 295 347 2.1E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 433 446 9.9E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 302 319 9.9E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 341 357 9.9E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 407 422 9.9E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 SUPERFAMILY SSF51338 1 184 6.01E-57 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 ProSitePatterns PS00145 Urease active site. 324 340 - T 06-07-2017 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 Pfam PF01979 Amidohydrolase family 132 457 1.5E-69 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 Hamap MF_01953 Urease subunit alpha [ureC]. 2 573 55.417 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 Gene3D G3DSA:3.20.20.140 494 571 3.3E-194 T 06-07-2017 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 Gene3D G3DSA:3.20.20.140 143 435 3.3E-194 T 06-07-2017 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 ProSitePatterns PS01120 Urease nickel ligands signature. 134 147 - T 06-07-2017 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 3 573 2.4E-266 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 Gene3D G3DSA:2.30.40.10 72 142 1.0E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 126 2.6E-53 T 06-07-2017 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 SUPERFAMILY SSF51556 487 573 3.23E-187 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS02305 eb4c327e5cdd83e25480174a20fffd8d 573 SUPERFAMILY SSF51556 136 438 3.23E-187 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS07440 5e76a3fab85421adf4eafa63c2cc92b2 263 SUPERFAMILY SSF110399 4 242 9.94E-82 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 LK06_RS07440 5e76a3fab85421adf4eafa63c2cc92b2 263 Pfam PF05690 Thiazole biosynthesis protein ThiG 8 250 6.2E-107 T 06-07-2017 LK06_RS07440 5e76a3fab85421adf4eafa63c2cc92b2 263 Hamap MF_00443 Thiazole synthase [thiG]. 5 256 42.54 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 LK06_RS07440 5e76a3fab85421adf4eafa63c2cc92b2 263 Gene3D G3DSA:3.20.20.70 7 256 1.1E-56 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 SUPERFAMILY SSF46894 188 250 2.24E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 SUPERFAMILY SSF52172 20 144 3.7E-28 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 Gene3D G3DSA:3.40.50.2300 20 137 7.1E-30 T 06-07-2017 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 Gene3D G3DSA:3.40.50.2300 182 198 7.1E-30 T 06-07-2017 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 ProSitePatterns PS00622 LuxR-type HTH domain signature. 209 236 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 Pfam PF00072 Response regulator receiver domain 24 119 1.6E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 SMART SM00448 21 132 1.2E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 Pfam PF00196 Bacterial regulatory proteins, luxR family 195 246 3.2E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 SMART SM00421 192 249 1.5E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 209 4.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 225 237 4.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 209 225 4.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 Gene3D G3DSA:1.10.10.10 199 247 8.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21295 4ca6493e0f1ce83d6f27fa8ab2d2b795 253 Gene3D G3DSA:1.10.10.10 138 159 8.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06065 fa30459f24bbf1b05ed07e47f632fde6 516 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 437 447 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site LK06_RS06065 fa30459f24bbf1b05ed07e47f632fde6 516 Pfam PF00082 Subtilase family 180 473 6.6E-45 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS06065 fa30459f24bbf1b05ed07e47f632fde6 516 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 231 241 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site LK06_RS06065 fa30459f24bbf1b05ed07e47f632fde6 516 Gene3D G3DSA:3.40.50.200 154 515 4.2E-79 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS06065 fa30459f24bbf1b05ed07e47f632fde6 516 SUPERFAMILY SSF52743 367 515 8.77E-72 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS06065 fa30459f24bbf1b05ed07e47f632fde6 516 SUPERFAMILY SSF52743 160 340 8.77E-72 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS06065 fa30459f24bbf1b05ed07e47f632fde6 516 PRINTS PR00723 Subtilisin serine protease family (S8) signature 227 240 3.1E-18 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS06065 fa30459f24bbf1b05ed07e47f632fde6 516 PRINTS PR00723 Subtilisin serine protease family (S8) signature 436 452 3.1E-18 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS06065 fa30459f24bbf1b05ed07e47f632fde6 516 PRINTS PR00723 Subtilisin serine protease family (S8) signature 179 198 3.1E-18 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS06065 fa30459f24bbf1b05ed07e47f632fde6 516 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 184 195 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site LK06_RS32095 250a35a114e9ef08811c50ce087d59c9 421 Pfam PF13535 ATP-grasp domain 139 285 3.1E-17 T 06-07-2017 LK06_RS32095 250a35a114e9ef08811c50ce087d59c9 421 SUPERFAMILY SSF56059 101 314 6.73E-32 T 06-07-2017 LK06_RS32095 250a35a114e9ef08811c50ce087d59c9 421 Gene3D G3DSA:3.30.470.20 104 318 1.5E-22 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS23845 dd41ffb7c40149fc7f57e3f05813d252 376 Pfam PF03054 tRNA methyl transferase 12 365 8.7E-118 T 06-07-2017 LK06_RS23845 dd41ffb7c40149fc7f57e3f05813d252 376 Gene3D G3DSA:3.40.50.620 8 222 6.5E-76 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS23845 dd41ffb7c40149fc7f57e3f05813d252 376 Gene3D G3DSA:2.30.30.280 225 285 2.0E-15 T 06-07-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 LK06_RS23845 dd41ffb7c40149fc7f57e3f05813d252 376 Gene3D G3DSA:2.40.30.10 292 371 5.9E-19 T 06-07-2017 LK06_RS23845 dd41ffb7c40149fc7f57e3f05813d252 376 SUPERFAMILY SSF52402 12 255 2.14E-46 T 06-07-2017 LK06_RS23845 dd41ffb7c40149fc7f57e3f05813d252 376 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 13 365 9.5E-86 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 LK06_RS23845 dd41ffb7c40149fc7f57e3f05813d252 376 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 11 366 35.975 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 LK06_RS29545 bd2f30aca2a025ddc568fc00ae668749 146 Pfam PF03771 Domain of unknown function (DUF317) 54 107 1.3E-12 T 06-07-2017 IPR005523 Domain of unknown function DUF317 LK06_RS23775 26e026485c02e4ec88e7821ee96195fb 596 Gene3D G3DSA:3.10.105.10 348 559 1.4E-31 T 06-07-2017 LK06_RS23775 26e026485c02e4ec88e7821ee96195fb 596 Gene3D G3DSA:3.90.76.10 72 241 1.0E-33 T 06-07-2017 LK06_RS23775 26e026485c02e4ec88e7821ee96195fb 596 Gene3D G3DSA:3.40.190.10 242 347 2.5E-19 T 06-07-2017 LK06_RS23775 26e026485c02e4ec88e7821ee96195fb 596 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 504 3.2E-72 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS23775 26e026485c02e4ec88e7821ee96195fb 596 PIRSF PIRSF002741 11 586 2.1E-57 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LK06_RS23775 26e026485c02e4ec88e7821ee96195fb 596 SUPERFAMILY SSF53850 60 590 6.65E-93 T 06-07-2017 LK06_RS27465 dabb8a6095a4b31a013a8304b8cfbee5 509 Pfam PF06276 Ferric iron reductase FhuF-like transporter 362 495 5.9E-24 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain LK06_RS27465 dabb8a6095a4b31a013a8304b8cfbee5 509 Pfam PF04183 IucA / IucC family 136 346 6.4E-36 T 06-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 LK06_RS27685 3aeba6b1ac29a97541c40b75260978bc 324 SMART SM00470 18 101 5.5E-11 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS27685 3aeba6b1ac29a97541c40b75260978bc 324 Pfam PF02195 ParB-like nuclease domain 41 100 4.5E-8 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS27685 3aeba6b1ac29a97541c40b75260978bc 324 SUPERFAMILY SSF110849 41 102 5.23E-9 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS27685 3aeba6b1ac29a97541c40b75260978bc 324 Gene3D G3DSA:3.90.1530.10 48 103 5.7E-7 T 06-07-2017 LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 57 176 2.6E-24 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 230 396 4.6E-21 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 SUPERFAMILY SSF52540 56 217 6.95E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 Hamap MF_00195 GTPase Der [der]. 54 486 35.447 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 Gene3D G3DSA:3.30.300.20 411 485 8.9E-27 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 55 483 1.0E-156 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 SMART SM00382 53 217 1.0 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 SMART SM00382 228 371 0.0069 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 Pfam PF01926 50S ribosome-binding GTPase 57 171 9.1E-25 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 Pfam PF01926 50S ribosome-binding GTPase 231 349 3.7E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 SUPERFAMILY SSF52540 189 487 1.64E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 281 296 6.7E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 232 252 6.7E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 405 483 4.5E-24 T 06-07-2017 IPR032859 GTPase Der, C-terminal KH-domain-like LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 PIRSF PIRSF006485 53 491 6.0E-157 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 Gene3D G3DSA:3.40.50.300 55 218 1.1E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05635 2b3e907725cff7dbf1114028efefae89 493 Gene3D G3DSA:3.40.50.300 230 410 5.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27590 b22af35a93cb92fbd81c0645ab37113a 381 Gene3D G3DSA:3.30.420.40 38 172 2.8E-44 T 06-07-2017 LK06_RS27590 b22af35a93cb92fbd81c0645ab37113a 381 Gene3D G3DSA:3.30.420.40 173 321 7.3E-51 T 06-07-2017 LK06_RS27590 b22af35a93cb92fbd81c0645ab37113a 381 Pfam PF00480 ROK family 38 348 5.8E-80 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS27590 b22af35a93cb92fbd81c0645ab37113a 381 ProSitePatterns PS01125 ROK family signature. 167 194 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS27590 b22af35a93cb92fbd81c0645ab37113a 381 SUPERFAMILY SSF53067 38 349 7.26E-69 T 06-07-2017 LK06_RS27590 b22af35a93cb92fbd81c0645ab37113a 381 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 39 348 1.9E-92 T 06-07-2017 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 LK06_RS30895 f39a2c1a7f2ab57b248de124cbf38191 209 SUPERFAMILY SSF51197 33 204 8.51E-43 T 06-07-2017 LK06_RS30895 f39a2c1a7f2ab57b248de124cbf38191 209 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 100 204 4.2E-14 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like LK06_RS30895 f39a2c1a7f2ab57b248de124cbf38191 209 Gene3D G3DSA:2.60.120.590 103 204 2.4E-17 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like LK06_RS15205 8c3e09aecdd34dc0beb592794332d733 548 SUPERFAMILY SSF51445 8 481 7.15E-124 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS15205 8c3e09aecdd34dc0beb592794332d733 548 Pfam PF00128 Alpha amylase, catalytic domain 34 399 5.2E-74 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS15205 8c3e09aecdd34dc0beb592794332d733 548 Gene3D G3DSA:3.90.400.10 111 183 2.5E-30 T 06-07-2017 LK06_RS15205 8c3e09aecdd34dc0beb592794332d733 548 Pfam PF11941 Domain of unknown function (DUF3459) 472 547 4.0E-6 T 06-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) LK06_RS15205 8c3e09aecdd34dc0beb592794332d733 548 Gene3D G3DSA:3.20.20.80 8 110 4.8E-102 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS15205 8c3e09aecdd34dc0beb592794332d733 548 Gene3D G3DSA:3.20.20.80 184 481 4.8E-102 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS15205 8c3e09aecdd34dc0beb592794332d733 548 SMART SM00642 19 427 1.5E-119 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS29400 042757ac6adaff410f4c42e7266e2e15 559 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 184 6.0E-19 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS29400 042757ac6adaff410f4c42e7266e2e15 559 Gene3D G3DSA:3.40.33.10 435 549 1.8E-15 T 06-07-2017 IPR014044 CAP domain LK06_RS29400 042757ac6adaff410f4c42e7266e2e15 559 SUPERFAMILY SSF88946 1 104 1.04E-21 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS29400 042757ac6adaff410f4c42e7266e2e15 559 Pfam PF00188 Cysteine-rich secretory protein family 441 555 1.9E-23 T 06-07-2017 IPR014044 CAP domain LK06_RS29400 042757ac6adaff410f4c42e7266e2e15 559 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 49 80 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS29400 042757ac6adaff410f4c42e7266e2e15 559 Gene3D G3DSA:1.10.1740.10 7 107 6.0E-22 T 06-07-2017 LK06_RS29400 042757ac6adaff410f4c42e7266e2e15 559 SUPERFAMILY SSF55797 435 556 7.06E-26 T 06-07-2017 IPR014044 CAP domain LK06_RS29400 042757ac6adaff410f4c42e7266e2e15 559 Pfam PF04542 Sigma-70 region 2 27 92 2.2E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS06405 73121dc21306b8bd3a34855f3e56d8f3 483 Pfam PF05787 Bacterial protein of unknown function (DUF839) 154 468 3.5E-64 T 06-07-2017 IPR008557 Protein of unknown function DUF839 LK06_RS06405 73121dc21306b8bd3a34855f3e56d8f3 483 SUPERFAMILY SSF63829 220 466 1.11E-11 T 06-07-2017 LK06_RS06405 73121dc21306b8bd3a34855f3e56d8f3 483 Gene3D G3DSA:2.130.10.10 224 462 1.8E-8 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS10300 75642ec855b40e7ebcdcbff91cf9a96d 185 Pfam PF06236 Tyrosinase co-factor MelC1 38 138 6.4E-30 T 06-07-2017 IPR010928 Tyrosinase co-factor MelC1 GO:0005507|GO:0042438 LK06_RS29235 c938e1cb169e97c81f324b032869b7ba 247 SMART SM00342 163 245 2.2E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS29235 c938e1cb169e97c81f324b032869b7ba 247 Pfam PF12833 Helix-turn-helix domain 171 242 3.3E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS29235 c938e1cb169e97c81f324b032869b7ba 247 Gene3D G3DSA:1.10.10.60 201 243 1.7E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS29235 c938e1cb169e97c81f324b032869b7ba 247 SUPERFAMILY SSF51182 14 169 4.27E-16 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS29235 c938e1cb169e97c81f324b032869b7ba 247 SUPERFAMILY SSF46689 199 243 9.86E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS29235 c938e1cb169e97c81f324b032869b7ba 247 Gene3D G3DSA:2.60.120.10 15 87 4.3E-9 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS29235 c938e1cb169e97c81f324b032869b7ba 247 Gene3D G3DSA:1.10.10.60 142 200 2.2E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS29235 c938e1cb169e97c81f324b032869b7ba 247 Pfam PF02311 AraC-like ligand binding domain 18 114 4.6E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 SUPERFAMILY SSF55874 264 390 9.69E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 371 3.9E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 348 3.9E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 390 3.9E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 Pfam PF13185 GAF domain 23 177 1.6E-19 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 SUPERFAMILY SSF55781 9 190 1.83E-28 T 06-07-2017 IPR029016 GAF domain-like LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 Gene3D G3DSA:3.30.450.40 18 185 2.4E-28 T 06-07-2017 IPR029016 GAF domain-like LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 SMART SM00065 24 187 1.8E-20 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 Gene3D G3DSA:3.30.565.10 279 390 3.8E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 390 1.7E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 Pfam PF07730 Histidine kinase 194 261 2.1E-17 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS05925 9d07eb9187a0ab1ffff4d1acd6cbfc78 392 SMART SM00387 298 392 8.4E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS06435 47f536c21be3ded5c93823c79204c3e7 328 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 120 160 1.1E-16 T 06-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 LK06_RS06435 47f536c21be3ded5c93823c79204c3e7 328 Gene3D G3DSA:3.30.60.70 120 160 1.9E-13 T 06-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 LK06_RS06435 47f536c21be3ded5c93823c79204c3e7 328 Gene3D G3DSA:2.160.10.10 161 315 3.3E-32 T 06-07-2017 LK06_RS06435 47f536c21be3ded5c93823c79204c3e7 328 SUPERFAMILY SSF51161 80 306 6.79E-37 T 06-07-2017 IPR011004 Trimeric LpxA-like LK06_RS06435 47f536c21be3ded5c93823c79204c3e7 328 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 10 327 4.3E-152 T 06-07-2017 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 LK06_RS06435 47f536c21be3ded5c93823c79204c3e7 328 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 8 325 43.461 T 06-07-2017 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 LK06_RS06435 47f536c21be3ded5c93823c79204c3e7 328 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 242 274 2.7E-14 T 06-07-2017 IPR001451 Hexapeptide repeat LK06_RS12340 fada9105e7a950409cd7910c93e1ae39 439 SUPERFAMILY SSF53300 65 106 1.34E-9 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS12340 fada9105e7a950409cd7910c93e1ae39 439 SUPERFAMILY SSF53300 148 201 1.34E-9 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS12340 fada9105e7a950409cd7910c93e1ae39 439 PRINTS PR01021 OMPA domain signature 329 351 1.7E-7 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LK06_RS12340 fada9105e7a950409cd7910c93e1ae39 439 PRINTS PR01021 OMPA domain signature 360 375 1.7E-7 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LK06_RS12340 fada9105e7a950409cd7910c93e1ae39 439 PRINTS PR01021 OMPA domain signature 375 391 1.7E-7 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LK06_RS12340 fada9105e7a950409cd7910c93e1ae39 439 Pfam PF00691 OmpA family 328 406 4.1E-13 T 06-07-2017 IPR006665 OmpA-like domain LK06_RS12340 fada9105e7a950409cd7910c93e1ae39 439 Gene3D G3DSA:3.30.1330.60 320 436 4.2E-23 T 06-07-2017 IPR006665 OmpA-like domain LK06_RS12340 fada9105e7a950409cd7910c93e1ae39 439 SUPERFAMILY SSF103088 321 436 6.8E-20 T 06-07-2017 IPR006665 OmpA-like domain LK06_RS02430 f071d20706c33d4c415d7ad716fd9cb4 181 Gene3D G3DSA:3.30.420.10 17 167 9.3E-27 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS02430 f071d20706c33d4c415d7ad716fd9cb4 181 Pfam PF00665 Integrase core domain 22 136 8.9E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 LK06_RS02430 f071d20706c33d4c415d7ad716fd9cb4 181 SUPERFAMILY SSF53098 16 178 5.16E-27 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS14115 81b25506081ebba17ffffbe278684936 399 Pfam PF13365 Trypsin-like peptidase domain 220 358 1.8E-19 T 06-07-2017 LK06_RS14115 81b25506081ebba17ffffbe278684936 399 Gene3D G3DSA:2.40.10.10 287 385 8.0E-12 T 06-07-2017 LK06_RS14115 81b25506081ebba17ffffbe278684936 399 SUPERFAMILY SSF50494 193 384 9.37E-34 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS14115 81b25506081ebba17ffffbe278684936 399 PRINTS PR00834 HtrA/DegQ protease family signature 250 270 1.5E-7 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS14115 81b25506081ebba17ffffbe278684936 399 PRINTS PR00834 HtrA/DegQ protease family signature 329 346 1.5E-7 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS14115 81b25506081ebba17ffffbe278684936 399 PRINTS PR00834 HtrA/DegQ protease family signature 228 240 1.5E-7 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS14115 81b25506081ebba17ffffbe278684936 399 Gene3D G3DSA:2.40.10.10 193 274 1.4E-13 T 06-07-2017 LK06_RS14115 81b25506081ebba17ffffbe278684936 399 Pfam PF02674 Colicin V production protein 4 143 5.7E-18 T 06-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 LK06_RS06085 e3f7a8764ab2532d6148017517b1567f 236 Pfam PF01988 VIT family 21 228 1.8E-57 T 06-07-2017 IPR008217 Ccc1 family LK06_RS24450 eb8a2f2f345b737336e669d0f5342dbb 262 SUPERFAMILY SSF51306 53 200 4.45E-36 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C LK06_RS24450 eb8a2f2f345b737336e669d0f5342dbb 262 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 103 115 5.1E-18 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24450 eb8a2f2f345b737336e669d0f5342dbb 262 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 151 170 5.1E-18 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24450 eb8a2f2f345b737336e669d0f5342dbb 262 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 52 68 5.1E-18 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24450 eb8a2f2f345b737336e669d0f5342dbb 262 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 40 197 7.4E-39 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LK06_RS24450 eb8a2f2f345b737336e669d0f5342dbb 262 Gene3D G3DSA:2.10.109.10 52 113 7.5E-26 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS24450 eb8a2f2f345b737336e669d0f5342dbb 262 Gene3D G3DSA:2.10.109.10 151 200 7.5E-26 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS24450 eb8a2f2f345b737336e669d0f5342dbb 262 Pfam PF00717 Peptidase S24-like 58 128 1.9E-11 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B LK06_RS18215 c5427b2c6154f16e9861ae2dfc95106d 142 Pfam PF00472 RF-1 domain 10 134 3.2E-21 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LK06_RS18215 c5427b2c6154f16e9861ae2dfc95106d 142 SUPERFAMILY SSF75620 11 102 1.29E-11 T 06-07-2017 LK06_RS18215 c5427b2c6154f16e9861ae2dfc95106d 142 Gene3D G3DSA:3.30.160.200 10 109 7.4E-27 T 06-07-2017 LK06_RS19460 4887092b954e94104308db010e9db7f3 184 Gene3D G3DSA:3.40.50.150 17 143 1.4E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19460 4887092b954e94104308db010e9db7f3 184 Pfam PF05063 MT-A70 19 177 3.4E-30 T 06-07-2017 IPR007757 MT-A70-like GO:0006139|GO:0008168 LK06_RS19460 4887092b954e94104308db010e9db7f3 184 SUPERFAMILY SSF53335 18 156 4.93E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS01200 4ce5136d6e08c5365364af12796fc71c 318 Gene3D G3DSA:3.40.50.720 157 241 7.4E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01200 4ce5136d6e08c5365364af12796fc71c 318 SMART SM00829 18 315 4.2E-51 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS01200 4ce5136d6e08c5365364af12796fc71c 318 SUPERFAMILY SSF51735 123 282 1.53E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01200 4ce5136d6e08c5365364af12796fc71c 318 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 151 172 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 LK06_RS01200 4ce5136d6e08c5365364af12796fc71c 318 Pfam PF13602 Zinc-binding dehydrogenase 194 315 9.0E-26 T 06-07-2017 LK06_RS01200 4ce5136d6e08c5365364af12796fc71c 318 Gene3D G3DSA:3.90.180.10 8 156 1.1E-47 T 06-07-2017 IPR011032 GroES-like LK06_RS01200 4ce5136d6e08c5365364af12796fc71c 318 SUPERFAMILY SSF50129 7 156 4.26E-40 T 06-07-2017 IPR011032 GroES-like LK06_RS01200 4ce5136d6e08c5365364af12796fc71c 318 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 97 2.0E-9 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS14380 30f117cfa9795b8e9cdbaa0e94c85fc4 70 Gene3D G3DSA:3.30.70.20 7 65 8.0E-9 T 06-07-2017 LK06_RS14380 30f117cfa9795b8e9cdbaa0e94c85fc4 70 SUPERFAMILY SSF54862 8 64 3.95E-7 T 06-07-2017 LK06_RS14380 30f117cfa9795b8e9cdbaa0e94c85fc4 70 Pfam PF13459 4Fe-4S single cluster domain 8 64 1.8E-13 T 06-07-2017 LK06_RS27075 bf220ac29ab25a20c1e332eba486cbbb 382 SUPERFAMILY SSF52540 112 345 6.08E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27075 bf220ac29ab25a20c1e332eba486cbbb 382 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 74 341 1.6E-41 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 LK06_RS27075 bf220ac29ab25a20c1e332eba486cbbb 382 Pfam PF03193 Protein of unknown function, DUF258 94 284 1.5E-37 T 06-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 LK06_RS27075 bf220ac29ab25a20c1e332eba486cbbb 382 Gene3D G3DSA:3.40.50.300 112 282 1.2E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27075 bf220ac29ab25a20c1e332eba486cbbb 382 Gene3D G3DSA:1.10.40.50 290 349 4.3E-21 T 06-07-2017 LK06_RS27075 bf220ac29ab25a20c1e332eba486cbbb 382 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 35 348 28.309 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 96 1.6E-7 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 124 195 6.3E-8 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 SUPERFAMILY SSF46946 123 202 3.01E-18 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 SUPERFAMILY SSF81624 2 125 9.94E-26 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 SMART SM00898 2 110 1.8E-20 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 SMART SM01232 124 214 3.2E-21 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 Gene3D G3DSA:3.20.190.10 2 124 1.7E-13 T 06-07-2017 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 SUPERFAMILY SSF57716 211 259 5.42E-9 T 06-07-2017 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 Gene3D G3DSA:1.10.8.50 125 259 1.4E-32 T 06-07-2017 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 ProSitePatterns PS01242 Zinc finger FPG-type signature. 231 259 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 LK06_RS25020 a89a0a22d73e88086f0ff24e7c6c8464 284 Pfam PF06827 Zinc finger found in FPG and IleRS 230 259 1.0E-4 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 LK06_RS05640 96c42c28659872f2a07a1e1fb3454689 222 Pfam PF01553 Acyltransferase 36 155 7.1E-16 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS05640 96c42c28659872f2a07a1e1fb3454689 222 SMART SM00563 48 158 4.2E-22 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS05640 96c42c28659872f2a07a1e1fb3454689 222 SUPERFAMILY SSF69593 26 211 4.32E-31 T 06-07-2017 LK06_RS05640 96c42c28659872f2a07a1e1fb3454689 222 Gene3D G3DSA:3.40.1130.10 33 214 1.3E-14 T 06-07-2017 LK06_RS31035 38e09fa47ccf4790d06e34b823f0dc49 156 Pfam PF00578 AhpC/TSA family 7 129 5.5E-29 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LK06_RS31035 38e09fa47ccf4790d06e34b823f0dc49 156 SUPERFAMILY SSF52833 4 151 6.77E-41 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS31035 38e09fa47ccf4790d06e34b823f0dc49 156 Gene3D G3DSA:3.40.30.10 4 151 1.1E-36 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS31035 38e09fa47ccf4790d06e34b823f0dc49 156 PIRSF PIRSF000239 2 152 8.6E-19 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 475 1.6E-203 T 06-07-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 2.3E-24 T 06-07-2017 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 2.3E-24 T 06-07-2017 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 2.3E-24 T 06-07-2017 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 2.3E-24 T 06-07-2017 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 SUPERFAMILY SSF46548 11 154 9.42E-35 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 457 1.4E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 Gene3D G3DSA:1.10.1060.10 2 147 2.6E-36 T 06-07-2017 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 Gene3D G3DSA:3.40.50.720 401 482 1.3E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 Gene3D G3DSA:3.40.50.720 148 234 1.3E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 SUPERFAMILY SSF51971 362 468 6.71E-10 T 06-07-2017 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 SUPERFAMILY SSF51971 144 401 8.63E-67 T 06-07-2017 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 Gene3D G3DSA:3.50.50.60 235 400 2.4E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07035 9fc205bb8aafaefd6a50a8e6de6c821a 487 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 40 131 1.1E-21 T 06-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 LK06_RS29050 f4255a5145a285bfd5f8cf198c927889 334 SUPERFAMILY SSF51735 2 147 9.22E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29050 f4255a5145a285bfd5f8cf198c927889 334 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 130 234 2.9E-9 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 LK06_RS29050 f4255a5145a285bfd5f8cf198c927889 334 Gene3D G3DSA:3.40.50.720 1 130 1.5E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29050 f4255a5145a285bfd5f8cf198c927889 334 Gene3D G3DSA:3.30.360.10 131 328 1.6E-50 T 06-07-2017 LK06_RS29050 f4255a5145a285bfd5f8cf198c927889 334 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 118 1.0E-19 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 LK06_RS29050 f4255a5145a285bfd5f8cf198c927889 334 SUPERFAMILY SSF55347 126 284 7.36E-26 T 06-07-2017 LK06_RS31235 f827646f611133b6e8afdb8cfd484a41 390 Pfam PF01594 Domain of unknown function DUF20 64 385 8.9E-47 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 SUPERFAMILY SSF50692 587 712 1.85E-28 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 Pfam PF00384 Molybdopterin oxidoreductase 61 430 1.1E-34 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 Gene3D G3DSA:2.40.40.20 584 712 6.1E-25 T 06-07-2017 LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 SUPERFAMILY SSF53706 5 496 3.66E-112 T 06-07-2017 LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 Gene3D G3DSA:2.20.25.90 3 62 4.5E-15 T 06-07-2017 LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 Gene3D G3DSA:3.40.50.740 323 509 8.7E-46 T 06-07-2017 LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 Gene3D G3DSA:3.40.50.740 63 138 8.7E-46 T 06-07-2017 LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 Pfam PF01568 Molydopterin dinucleotide binding domain 588 705 5.2E-20 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 53 1.8E-9 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 Gene3D G3DSA:3.40.228.10 141 322 1.1E-38 T 06-07-2017 LK06_RS02735 bc322633a4b21fd84bbc738feb5c6043 715 SMART SM00926 3 57 5.5E-14 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS31540 8983fb2a25497f69be9eab4ec5c37e0d 173 SUPERFAMILY SSF88659 110 168 2.16E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31540 8983fb2a25497f69be9eab4ec5c37e0d 173 Pfam PF08281 Sigma-70, region 4 117 163 2.3E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31540 8983fb2a25497f69be9eab4ec5c37e0d 173 Pfam PF04542 Sigma-70 region 2 33 93 5.2E-6 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31540 8983fb2a25497f69be9eab4ec5c37e0d 173 Gene3D G3DSA:1.10.1740.10 12 103 2.3E-17 T 06-07-2017 LK06_RS31540 8983fb2a25497f69be9eab4ec5c37e0d 173 Gene3D G3DSA:1.10.10.10 108 170 1.4E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31540 8983fb2a25497f69be9eab4ec5c37e0d 173 SUPERFAMILY SSF88946 9 93 6.47E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS31540 8983fb2a25497f69be9eab4ec5c37e0d 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 167 1.3E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15270 cfe33cd52f986a7b95f69a309b413844 267 Gene3D G3DSA:3.40.50.1820 25 265 1.5E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS15270 cfe33cd52f986a7b95f69a309b413844 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 9.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS15270 cfe33cd52f986a7b95f69a309b413844 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 9.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS15270 cfe33cd52f986a7b95f69a309b413844 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 9.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS15270 cfe33cd52f986a7b95f69a309b413844 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 208 222 9.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS15270 cfe33cd52f986a7b95f69a309b413844 267 SUPERFAMILY SSF53474 25 264 1.61E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS15270 cfe33cd52f986a7b95f69a309b413844 267 Pfam PF12697 Alpha/beta hydrolase family 27 256 5.9E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS11660 b7c6ee4a5fa544b6a663cbf6767969ed 423 Pfam PF09594 Protein of unknown function (DUF2029) 69 316 4.3E-13 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 LK06_RS11660 b7c6ee4a5fa544b6a663cbf6767969ed 423 PIRSF PIRSF010361 1 419 3.0E-74 T 06-07-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 Gene3D G3DSA:3.30.379.10 83 191 9.5E-17 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 208 514 6.7E-39 T 06-07-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 85 201 5.9E-13 T 06-07-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 SUPERFAMILY SSF55545 78 203 6.41E-15 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 SUPERFAMILY SSF51445 206 544 2.19E-75 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 496 512 3.4E-21 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 199 216 3.4E-21 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 276 293 3.4E-21 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 167 187 3.4E-21 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 318 336 3.4E-21 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 340 353 3.4E-21 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS20560 d03d70afafa41f8be0600da0f5cf3ff2 552 Gene3D G3DSA:3.20.20.80 192 536 2.7E-69 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS21330 b265daceacaf2a337cc532c2dd8bbb85 264 Gene3D G3DSA:3.40.50.150 54 261 8.5E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS21330 b265daceacaf2a337cc532c2dd8bbb85 264 Pfam PF08241 Methyltransferase domain 58 150 1.5E-7 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS21330 b265daceacaf2a337cc532c2dd8bbb85 264 SUPERFAMILY SSF53335 43 194 1.26E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28095 94f0133c0615a63a4fc38a299e6ebe6b 273 SUPERFAMILY SSF53335 10 262 1.16E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28095 94f0133c0615a63a4fc38a299e6ebe6b 273 Pfam PF13847 Methyltransferase domain 39 152 4.1E-29 T 06-07-2017 IPR025714 Methyltransferase domain LK06_RS28095 94f0133c0615a63a4fc38a299e6ebe6b 273 Gene3D G3DSA:3.40.50.150 9 265 1.8E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS11255 6ab5487336cfcb055c5532f820ef6bee 197 Pfam PF00857 Isochorismatase family 4 190 1.8E-32 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS11255 6ab5487336cfcb055c5532f820ef6bee 197 Gene3D G3DSA:3.40.50.850 1 190 7.0E-58 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS11255 6ab5487336cfcb055c5532f820ef6bee 197 SUPERFAMILY SSF52499 2 190 2.88E-48 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS22500 7a6811e9878c3e0beb710c140af4a141 468 Pfam PF00027 Cyclic nucleotide-binding domain 114 201 5.2E-16 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain LK06_RS22500 7a6811e9878c3e0beb710c140af4a141 468 SUPERFAMILY SSF51206 77 214 1.11E-23 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like LK06_RS22500 7a6811e9878c3e0beb710c140af4a141 468 Gene3D G3DSA:2.60.120.10 90 212 3.1E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS22500 7a6811e9878c3e0beb710c140af4a141 468 SMART SM00100 94 217 1.6E-11 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 Gene3D G3DSA:1.20.120.520 638 774 1.1E-12 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 541 553 1.4E-24 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 321 335 1.4E-24 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 442 453 1.4E-24 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 179 193 1.4E-24 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 517 536 1.4E-24 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 465 475 1.4E-24 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 Gene3D G3DSA:2.70.150.10 84 230 7.8E-19 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 Pfam PF00702 haloacid dehalogenase-like hydrolase 318 531 3.6E-34 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 SUPERFAMILY SSF81653 132 228 1.7E-20 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 79 619 1.5E-160 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 Pfam PF00122 E1-E2 ATPase 100 312 2.9E-51 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 323 329 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 428 597 1.2E-31 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 102 341 9.9E-30 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 Pfam PF01814 Hemerythrin HHE cation binding domain 638 775 1.2E-18 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 Gene3D G3DSA:3.40.1110.10 348 408 8.8E-9 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 SUPERFAMILY SSF81665 230 315 1.02E-10 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 SUPERFAMILY SSF81665 85 133 1.02E-10 T 06-07-2017 LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 Gene3D G3DSA:3.40.50.1000 437 578 9.0E-34 T 06-07-2017 IPR023214 HAD-like domain LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 SUPERFAMILY SSF56784 378 618 1.02E-43 T 06-07-2017 IPR023214 HAD-like domain LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 SUPERFAMILY SSF56784 320 339 1.02E-43 T 06-07-2017 IPR023214 HAD-like domain LK06_RS14385 6ff741347716662a4dcb17f7d37713da 776 Gene3D G3DSA:1.20.1110.10 266 347 4.7E-4 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 LK06_RS19585 b071f32beda878f26f1dcf51a2bf36d2 267 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 258 3.2E-29 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS19585 b071f32beda878f26f1dcf51a2bf36d2 267 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 265 7.5E-75 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 LK06_RS19585 b071f32beda878f26f1dcf51a2bf36d2 267 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 4 265 1.7E-73 T 06-07-2017 LK06_RS19585 b071f32beda878f26f1dcf51a2bf36d2 267 SUPERFAMILY SSF56219 2 266 1.83E-75 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS19585 b071f32beda878f26f1dcf51a2bf36d2 267 Gene3D G3DSA:3.60.10.10 2 265 5.3E-92 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS22375 3a8e71bd29d8e75fdcd64d0acf9fb902 208 Gene3D G3DSA:3.40.50.1820 21 188 4.1E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22375 3a8e71bd29d8e75fdcd64d0acf9fb902 208 SUPERFAMILY SSF53474 6 188 7.58E-15 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS14770 78d193721d0b13d843627db65775357c 755 Pfam PF02754 Cysteine-rich domain 616 703 4.1E-19 T 06-07-2017 IPR004017 Cysteine-rich domain LK06_RS14770 78d193721d0b13d843627db65775357c 755 Pfam PF02754 Cysteine-rich domain 478 577 4.2E-13 T 06-07-2017 IPR004017 Cysteine-rich domain LK06_RS14770 78d193721d0b13d843627db65775357c 755 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 302 313 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS14770 78d193721d0b13d843627db65775357c 755 Pfam PF13183 4Fe-4S dicluster domain 299 407 2.4E-14 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LK06_RS14770 78d193721d0b13d843627db65775357c 755 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 393 404 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS14770 78d193721d0b13d843627db65775357c 755 SUPERFAMILY SSF46548 285 338 8.89E-22 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 LK06_RS14770 78d193721d0b13d843627db65775357c 755 SUPERFAMILY SSF46548 375 421 8.89E-22 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 LK06_RS14770 78d193721d0b13d843627db65775357c 755 Gene3D G3DSA:1.10.1060.10 372 422 5.2E-32 T 06-07-2017 LK06_RS14770 78d193721d0b13d843627db65775357c 755 Gene3D G3DSA:1.10.1060.10 280 335 5.2E-32 T 06-07-2017 LK06_RS13470 284980e90b032ade8e3d6d180c37acf5 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 14 61 9.7E-21 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 LK06_RS13470 284980e90b032ade8e3d6d180c37acf5 70 SUPERFAMILY SSF46955 14 62 5.31E-5 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS13470 284980e90b032ade8e3d6d180c37acf5 70 Gene3D G3DSA:1.10.10.10 15 62 6.4E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13470 284980e90b032ade8e3d6d180c37acf5 70 Pfam PF12728 Helix-turn-helix domain 14 61 4.7E-14 T 06-07-2017 LK06_RS20430 790c65e6adb6cfe3495ae3815c3c5e2a 321 Gene3D G3DSA:3.40.190.10 39 118 1.9E-24 T 06-07-2017 LK06_RS20430 790c65e6adb6cfe3495ae3815c3c5e2a 321 Gene3D G3DSA:3.40.190.10 254 321 1.9E-24 T 06-07-2017 LK06_RS20430 790c65e6adb6cfe3495ae3815c3c5e2a 321 Gene3D G3DSA:3.40.190.100 127 248 1.3E-26 T 06-07-2017 LK06_RS20430 790c65e6adb6cfe3495ae3815c3c5e2a 321 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 42 309 1.9E-49 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 LK06_RS20430 790c65e6adb6cfe3495ae3815c3c5e2a 321 SUPERFAMILY SSF53850 39 320 9.77E-57 T 06-07-2017 LK06_RS13155 de69b240c1184c5d3f06230f5ec9a34d 290 Pfam PF13704 Glycosyl transferase family 2 16 110 1.6E-6 T 06-07-2017 LK06_RS29180 bbca3c09c048dc04c9428bd856c1afbb 323 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 280 7.7E-49 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS29180 bbca3c09c048dc04c9428bd856c1afbb 323 Gene3D G3DSA:3.40.50.1100 35 138 8.9E-24 T 06-07-2017 LK06_RS29180 bbca3c09c048dc04c9428bd856c1afbb 323 Gene3D G3DSA:3.40.50.1100 139 306 5.0E-47 T 06-07-2017 LK06_RS29180 bbca3c09c048dc04c9428bd856c1afbb 323 SUPERFAMILY SSF53686 20 311 7.6E-70 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS29180 bbca3c09c048dc04c9428bd856c1afbb 323 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 15 307 6.4E-113 T 06-07-2017 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA LK06_RS27245 f9e3231a9055f9474da478bb136df9a7 422 Pfam PF13535 ATP-grasp domain 143 292 4.6E-24 T 06-07-2017 LK06_RS27245 f9e3231a9055f9474da478bb136df9a7 422 Gene3D G3DSA:3.30.470.20 103 308 3.0E-16 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS27245 f9e3231a9055f9474da478bb136df9a7 422 SUPERFAMILY SSF56059 97 313 4.42E-30 T 06-07-2017 LK06_RS16735 d50bcd0813bcb8008ebb59552e50cce6 810 Pfam PF13625 Helicase conserved C-terminal domain 506 625 1.4E-28 T 06-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 LK06_RS05225 b61509db73c6265bfc1d34459ecb679a 143 SUPERFAMILY SSF54427 42 138 2.83E-31 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS05225 b61509db73c6265bfc1d34459ecb679a 143 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 5 137 26.882 T 06-07-2017 IPR023006 Uncharacterised protein family UPF0225 LK06_RS05225 b61509db73c6265bfc1d34459ecb679a 143 Gene3D G3DSA:3.10.450.50 8 138 5.9E-34 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 SUPERFAMILY SSF51735 58 185 6.19E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 Pfam PF13380 CoA binding domain 65 185 2.4E-16 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 SUPERFAMILY SSF52210 342 499 7.33E-26 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 SUPERFAMILY SSF56059 532 743 4.77E-43 T 06-07-2017 LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 Gene3D G3DSA:3.40.50.720 53 180 2.0E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 Gene3D G3DSA:3.40.50.261 181 334 1.0E-14 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 202 336 3.7E-43 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 Pfam PF13549 ATP-grasp domain 524 742 1.9E-65 T 06-07-2017 LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 SMART SM00881 60 155 1.2E-19 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 Gene3D G3DSA:3.30.470.20 536 578 3.4E-7 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS18855 0b3b252331bcfb7c259b62601d5d425a 745 SUPERFAMILY SSF52210 193 338 1.19E-31 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS01085 dac532f36c2482f027190bc2ddee5459 584 Pfam PF00652 Ricin-type beta-trefoil lectin domain 429 552 2.8E-16 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS01085 dac532f36c2482f027190bc2ddee5459 584 SUPERFAMILY SSF50370 427 554 1.35E-18 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS01085 dac532f36c2482f027190bc2ddee5459 584 SMART SM00458 427 555 1.7E-6 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS01085 dac532f36c2482f027190bc2ddee5459 584 Gene3D G3DSA:2.80.10.50 424 555 6.8E-15 T 06-07-2017 LK06_RS24640 b7512e47c2382e33758c6868c0d14a4a 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 258 9.8E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24640 b7512e47c2382e33758c6868c0d14a4a 266 Gene3D G3DSA:1.10.3720.10 8 264 5.3E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24640 b7512e47c2382e33758c6868c0d14a4a 266 SUPERFAMILY SSF161098 6 256 1.96E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS09610 b10401bb1f19d11fb1179b77faa2da4c 147 Pfam PF02410 Ribosomal silencing factor during starvation 14 109 3.3E-22 T 06-07-2017 LK06_RS09610 b10401bb1f19d11fb1179b77faa2da4c 147 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 11 109 9.7E-30 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS LK06_RS09610 b10401bb1f19d11fb1179b77faa2da4c 147 Gene3D G3DSA:3.30.460.10 8 113 6.1E-33 T 06-07-2017 LK06_RS09610 b10401bb1f19d11fb1179b77faa2da4c 147 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 110 23.012 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS LK06_RS09610 b10401bb1f19d11fb1179b77faa2da4c 147 SUPERFAMILY SSF81301 7 118 1.29E-35 T 06-07-2017 LK06_RS31855 4a02efbbacfff02c6f98c91dfce4f9e5 279 SMART SM00849 53 266 4.6E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS31855 4a02efbbacfff02c6f98c91dfce4f9e5 279 Pfam PF00753 Metallo-beta-lactamase superfamily 52 255 5.2E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS31855 4a02efbbacfff02c6f98c91dfce4f9e5 279 Gene3D G3DSA:3.60.15.10 49 272 1.7E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS31855 4a02efbbacfff02c6f98c91dfce4f9e5 279 SUPERFAMILY SSF56281 21 269 1.44E-24 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS22265 579dd0072a2d7df14c99ed98d2e9e45c 556 Pfam PF02342 TerD domain 1 170 8.7E-36 T 06-07-2017 IPR003325 TerD domain GO:0006950 LK06_RS22265 579dd0072a2d7df14c99ed98d2e9e45c 556 SUPERFAMILY SSF51219 359 555 3.66E-33 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain LK06_RS22265 579dd0072a2d7df14c99ed98d2e9e45c 556 Gene3D G3DSA:3.60.160.10 359 549 1.5E-27 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS22265 579dd0072a2d7df14c99ed98d2e9e45c 556 Pfam PF01987 Mitochondrial biogenesis AIM24 361 552 8.5E-22 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS22265 579dd0072a2d7df14c99ed98d2e9e45c 556 Gene3D G3DSA:2.60.60.30 34 167 1.1E-26 T 06-07-2017 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 49 524 40.986 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 Gene3D G3DSA:3.40.50.10490 16 101 1.4E-128 T 06-07-2017 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 Gene3D G3DSA:3.40.50.10490 297 506 1.4E-128 T 06-07-2017 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 Gene3D G3DSA:3.40.50.10490 102 294 1.8E-84 T 06-07-2017 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 Pfam PF00342 Phosphoglucose isomerase 55 541 1.2E-218 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 Gene3D G3DSA:1.10.1390.10 507 548 8.8E-20 T 06-07-2017 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 SUPERFAMILY SSF53697 11 548 6.12E-207 T 06-07-2017 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 06-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 342 363 1.6E-53 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 153 172 1.6E-53 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 1.6E-53 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 1.6E-53 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 265 283 1.6E-53 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS28385 9690f4e3cc6da501c6ade6337788d945 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 1.6E-53 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 1.1E-30 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 PRINTS PR00101 Aspartate carbamoyltransferase signature 267 272 1.1E-30 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.1E-30 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 1.1E-30 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 PRINTS PR00101 Aspartate carbamoyltransferase signature 291 305 1.1E-30 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 1.1E-30 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 4.4E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 4.4E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 4.4E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 4.4E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 Gene3D G3DSA:3.40.50.1370 2 142 1.9E-49 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 SUPERFAMILY SSF53671 2 312 2.36E-92 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 Gene3D G3DSA:3.40.50.1370 143 288 2.2E-48 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 147 1.3E-39 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 310 3.1E-91 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 312 41.115 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04130 417f2bfa02539857ba9031fd082c889e 318 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 309 2.8E-23 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 LK06_RS12165 ebed81cda659d4f7f5d188031d4d2ba4 288 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 260 31.448 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS12165 ebed81cda659d4f7f5d188031d4d2ba4 288 PIRSF PIRSF001430 9 277 8.7E-75 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS12165 ebed81cda659d4f7f5d188031d4d2ba4 288 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 12 254 4.6E-49 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS12165 ebed81cda659d4f7f5d188031d4d2ba4 288 Pfam PF01416 tRNA pseudouridine synthase 159 261 2.3E-22 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS12165 ebed81cda659d4f7f5d188031d4d2ba4 288 Pfam PF01416 tRNA pseudouridine synthase 17 78 1.0E-5 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS12165 ebed81cda659d4f7f5d188031d4d2ba4 288 SUPERFAMILY SSF55120 9 267 8.49E-71 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS12165 ebed81cda659d4f7f5d188031d4d2ba4 288 Gene3D G3DSA:3.30.70.580 11 120 8.4E-33 T 06-07-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS12165 ebed81cda659d4f7f5d188031d4d2ba4 288 Gene3D G3DSA:3.30.70.660 122 258 1.4E-36 T 06-07-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 LK06_RS14425 06ad5458ea4b3f9737382a562751e125 123 Gene3D G3DSA:3.40.30.10 3 102 1.1E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS14425 06ad5458ea4b3f9737382a562751e125 123 SUPERFAMILY SSF52833 3 103 5.08E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS14425 06ad5458ea4b3f9737382a562751e125 123 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 6.6E-29 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LK06_RS14425 06ad5458ea4b3f9737382a562751e125 123 Pfam PF00085 Thioredoxin 4 101 6.9E-25 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 LK06_RS14425 06ad5458ea4b3f9737382a562751e125 123 PRINTS PR00421 Thioredoxin family signature 21 29 2.2E-6 T 06-07-2017 LK06_RS14425 06ad5458ea4b3f9737382a562751e125 123 PRINTS PR00421 Thioredoxin family signature 68 79 2.2E-6 T 06-07-2017 LK06_RS14425 06ad5458ea4b3f9737382a562751e125 123 PRINTS PR00421 Thioredoxin family signature 29 38 2.2E-6 T 06-07-2017 LK06_RS14425 06ad5458ea4b3f9737382a562751e125 123 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 LK06_RS14425 06ad5458ea4b3f9737382a562751e125 123 PIRSF PIRSF000077 1 104 6.8E-26 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LK06_RS22075 b0de505594dca97deada7a275b0fd460 374 Pfam PF01544 CorA-like Mg2+ transporter protein 70 368 3.4E-60 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 LK06_RS22075 b0de505594dca97deada7a275b0fd460 374 SUPERFAMILY SSF143865 37 307 1.96E-63 T 06-07-2017 LK06_RS22075 b0de505594dca97deada7a275b0fd460 374 SUPERFAMILY SSF144083 310 371 1.09E-19 T 06-07-2017 LK06_RS22075 b0de505594dca97deada7a275b0fd460 374 Gene3D G3DSA:1.20.58.340 298 374 1.2E-26 T 06-07-2017 LK06_RS22075 b0de505594dca97deada7a275b0fd460 374 Gene3D G3DSA:3.30.460.20 28 178 2.0E-43 T 06-07-2017 LK06_RS22075 b0de505594dca97deada7a275b0fd460 374 Gene3D G3DSA:1.20.58.340 179 296 8.2E-40 T 06-07-2017 LK06_RS05885 17d67c89a995e7572b9828663b5a7ad0 168 SMART SM00507 71 120 2.0E-13 T 06-07-2017 IPR003615 HNH nuclease LK06_RS05885 17d67c89a995e7572b9828663b5a7ad0 168 Pfam PF14279 HNH endonuclease 84 134 9.9E-11 T 06-07-2017 IPR029471 HNH endonuclease 5 LK06_RS06365 64cd7463b66f49866b499c7375b2011a 257 SUPERFAMILY SSF46785 12 84 2.73E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06365 64cd7463b66f49866b499c7375b2011a 257 SUPERFAMILY SSF55781 79 253 1.44E-44 T 06-07-2017 IPR029016 GAF domain-like LK06_RS06365 64cd7463b66f49866b499c7375b2011a 257 Pfam PF09339 IclR helix-turn-helix domain 14 64 9.2E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS06365 64cd7463b66f49866b499c7375b2011a 257 Gene3D G3DSA:1.10.10.10 12 75 1.2E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06365 64cd7463b66f49866b499c7375b2011a 257 Pfam PF01614 Bacterial transcriptional regulator 134 243 1.6E-25 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal LK06_RS06365 64cd7463b66f49866b499c7375b2011a 257 SMART SM00346 12 102 1.0E-19 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS06365 64cd7463b66f49866b499c7375b2011a 257 Gene3D G3DSA:3.30.450.40 87 251 5.5E-50 T 06-07-2017 IPR029016 GAF domain-like LK06_RS10505 10c8c1b622b66c52747b42d18ff574d2 351 Gene3D G3DSA:1.25.40.10 113 314 1.1E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS10505 10c8c1b622b66c52747b42d18ff574d2 351 SUPERFAMILY SSF48452 113 308 6.21E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS14440 948e5470492f9450fb60f1ad61e2f9d6 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 1.6E-6 T 06-07-2017 LK06_RS14440 948e5470492f9450fb60f1ad61e2f9d6 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 1.6E-6 T 06-07-2017 LK06_RS14440 948e5470492f9450fb60f1ad61e2f9d6 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 407 426 1.6E-6 T 06-07-2017 LK06_RS14440 948e5470492f9450fb60f1ad61e2f9d6 463 SUPERFAMILY SSF103473 10 203 7.06E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS14440 948e5470492f9450fb60f1ad61e2f9d6 463 SUPERFAMILY SSF103473 257 459 7.06E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS14440 948e5470492f9450fb60f1ad61e2f9d6 463 Gene3D G3DSA:1.20.1250.20 271 461 2.5E-11 T 06-07-2017 LK06_RS14440 948e5470492f9450fb60f1ad61e2f9d6 463 Gene3D G3DSA:1.20.1250.20 10 203 4.1E-29 T 06-07-2017 LK06_RS14440 948e5470492f9450fb60f1ad61e2f9d6 463 Pfam PF07690 Major Facilitator Superfamily 26 416 5.7E-43 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS11390 eeba15ff88dd9b15009b129ddb0fb3d5 385 Pfam PF14435 SUKH-4 immunity protein 197 379 9.9E-44 T 06-07-2017 IPR025851 SUKH-4 immunity protein LK06_RS11390 eeba15ff88dd9b15009b129ddb0fb3d5 385 Pfam PF14435 SUKH-4 immunity protein 10 141 3.1E-7 T 06-07-2017 IPR025851 SUKH-4 immunity protein LK06_RS29295 c5b5f1da4ebfd65346262baa4de431ee 247 Gene3D G3DSA:3.80.30.10 74 245 9.0E-60 T 06-07-2017 LK06_RS29295 c5b5f1da4ebfd65346262baa4de431ee 247 Pfam PF13353 4Fe-4S single cluster domain 20 114 1.8E-17 T 06-07-2017 LK06_RS29295 c5b5f1da4ebfd65346262baa4de431ee 247 ProSitePatterns PS01087 Radical activating enzymes signature. 22 43 - T 06-07-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 LK06_RS29295 c5b5f1da4ebfd65346262baa4de431ee 247 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 10 242 1.0E-90 T 06-07-2017 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 LK06_RS29295 c5b5f1da4ebfd65346262baa4de431ee 247 Pfam PF04055 Radical SAM superfamily 30 179 1.8E-26 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS29295 c5b5f1da4ebfd65346262baa4de431ee 247 SUPERFAMILY SSF102114 27 217 2.09E-27 T 06-07-2017 LK06_RS25175 1eb22c0551526334047bac5f09f60187 497 Gene3D G3DSA:3.40.640.10 72 313 1.4E-61 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS25175 1eb22c0551526334047bac5f09f60187 497 Pfam PF00202 Aminotransferase class-III 32 472 9.4E-85 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS25175 1eb22c0551526334047bac5f09f60187 497 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 16 385 3.3E-126 T 06-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 LK06_RS25175 1eb22c0551526334047bac5f09f60187 497 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS25175 1eb22c0551526334047bac5f09f60187 497 SUPERFAMILY SSF53383 422 472 1.7E-106 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS25175 1eb22c0551526334047bac5f09f60187 497 SUPERFAMILY SSF53383 24 381 1.7E-106 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS25175 1eb22c0551526334047bac5f09f60187 497 Gene3D G3DSA:3.90.1150.10 314 379 1.0E-51 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS25175 1eb22c0551526334047bac5f09f60187 497 Gene3D G3DSA:3.90.1150.10 419 476 1.0E-51 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS18030 4a72e1ac07e33984a77457f2d36183b4 264 Pfam PF00589 Phage integrase family 19 185 4.2E-19 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS18030 4a72e1ac07e33984a77457f2d36183b4 264 SUPERFAMILY SSF56349 2 194 5.0E-37 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS18030 4a72e1ac07e33984a77457f2d36183b4 264 Gene3D G3DSA:1.10.443.10 2 193 2.8E-40 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 Pfam PF00931 NB-ARC domain 24 199 3.7E-7 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 Pfam PF13424 Tetratricopeptide repeat 631 697 7.0E-12 T 06-07-2017 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 Pfam PF13424 Tetratricopeptide repeat 464 529 3.1E-12 T 06-07-2017 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 Pfam PF13424 Tetratricopeptide repeat 547 613 4.3E-12 T 06-07-2017 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 SUPERFAMILY SSF48452 578 698 2.92E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 PRINTS PR00364 Disease resistance protein signature 29 44 2.6E-5 T 06-07-2017 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 PRINTS PR00364 Disease resistance protein signature 186 200 2.6E-5 T 06-07-2017 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 PRINTS PR00364 Disease resistance protein signature 101 115 2.6E-5 T 06-07-2017 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 Gene3D G3DSA:1.25.40.10 359 390 3.6E-25 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 Gene3D G3DSA:1.25.40.10 463 698 3.6E-25 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 SUPERFAMILY SSF52540 4 247 2.32E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08570 e95d475c416cc147b6fd9caa17bc707f 732 SUPERFAMILY SSF48452 494 613 8.85E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS03540 3e16bf1bae8ddb6e35fa49751f589319 283 Gene3D G3DSA:3.40.50.150 21 199 7.3E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03540 3e16bf1bae8ddb6e35fa49751f589319 283 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 15 262 1.0E-82 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 LK06_RS03540 3e16bf1bae8ddb6e35fa49751f589319 283 Pfam PF04072 Leucine carboxyl methyltransferase 17 193 7.7E-56 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 LK06_RS03540 3e16bf1bae8ddb6e35fa49751f589319 283 SUPERFAMILY SSF53335 13 271 1.66E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03735 df851fbd3afa4d51cf583339bdff883f 404 Pfam PF02371 Transposase IS116/IS110/IS902 family 274 357 7.7E-24 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 LK06_RS03735 df851fbd3afa4d51cf583339bdff883f 404 Pfam PF01548 Transposase 11 166 1.4E-45 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS12610 df851fbd3afa4d51cf583339bdff883f 404 Pfam PF02371 Transposase IS116/IS110/IS902 family 274 357 7.7E-24 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 LK06_RS12610 df851fbd3afa4d51cf583339bdff883f 404 Pfam PF01548 Transposase 11 166 1.4E-45 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS24420 c01d32577896d2a2dbbb2293aec5cd21 186 SUPERFAMILY SSF50447 3 85 2.08E-19 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS24420 c01d32577896d2a2dbbb2293aec5cd21 186 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 166 23.872 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 LK06_RS24420 c01d32577896d2a2dbbb2293aec5cd21 186 Pfam PF05239 PRC-barrel domain 93 166 7.2E-10 T 06-07-2017 IPR027275 PRC-barrel domain LK06_RS24420 c01d32577896d2a2dbbb2293aec5cd21 186 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 166 1.5E-45 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 LK06_RS24420 c01d32577896d2a2dbbb2293aec5cd21 186 Gene3D G3DSA:2.30.30.240 96 166 8.0E-20 T 06-07-2017 LK06_RS24420 c01d32577896d2a2dbbb2293aec5cd21 186 Pfam PF01782 RimM N-terminal domain 5 83 5.3E-24 T 06-07-2017 IPR002676 RimM protein GO:0006364 LK06_RS24420 c01d32577896d2a2dbbb2293aec5cd21 186 SUPERFAMILY SSF50346 96 166 8.44E-18 T 06-07-2017 IPR011033 PRC-barrel-like LK06_RS24420 c01d32577896d2a2dbbb2293aec5cd21 186 Gene3D G3DSA:2.40.30.60 3 90 1.9E-22 T 06-07-2017 IPR002676 RimM protein GO:0006364 LK06_RS12295 7031bdb31d2d8ccdb287f0cbabd8e04a 93 PIRSF PIRSF002144 1 93 3.6E-32 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12295 7031bdb31d2d8ccdb287f0cbabd8e04a 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 06-07-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12295 7031bdb31d2d8ccdb287f0cbabd8e04a 93 Pfam PF00203 Ribosomal protein S19 3 83 1.6E-37 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12295 7031bdb31d2d8ccdb287f0cbabd8e04a 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.199 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12295 7031bdb31d2d8ccdb287f0cbabd8e04a 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.1E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12295 7031bdb31d2d8ccdb287f0cbabd8e04a 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.1E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12295 7031bdb31d2d8ccdb287f0cbabd8e04a 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.1E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12295 7031bdb31d2d8ccdb287f0cbabd8e04a 93 SUPERFAMILY SSF54570 3 84 2.88E-35 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12295 7031bdb31d2d8ccdb287f0cbabd8e04a 93 Gene3D G3DSA:3.30.860.10 1 92 1.4E-41 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12295 7031bdb31d2d8ccdb287f0cbabd8e04a 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 3.2E-47 T 06-07-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 LK06_RS12085 5f8edbe0e68d21ededf08cc6acc42ef4 408 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 13 401 1.5E-85 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 LK06_RS12085 5f8edbe0e68d21ededf08cc6acc42ef4 408 SUPERFAMILY SSF55031 211 320 4.36E-21 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS12085 5f8edbe0e68d21ededf08cc6acc42ef4 408 Gene3D G3DSA:3.40.630.10 348 406 3.4E-91 T 06-07-2017 LK06_RS12085 5f8edbe0e68d21ededf08cc6acc42ef4 408 Gene3D G3DSA:3.40.630.10 5 221 3.4E-91 T 06-07-2017 LK06_RS12085 5f8edbe0e68d21ededf08cc6acc42ef4 408 PIRSF PIRSF001235 2 408 2.0E-125 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 LK06_RS12085 5f8edbe0e68d21ededf08cc6acc42ef4 408 Pfam PF01546 Peptidase family M20/M25/M40 72 403 1.3E-24 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 LK06_RS12085 5f8edbe0e68d21ededf08cc6acc42ef4 408 SUPERFAMILY SSF53187 333 406 1.18E-69 T 06-07-2017 LK06_RS12085 5f8edbe0e68d21ededf08cc6acc42ef4 408 SUPERFAMILY SSF53187 11 218 1.18E-69 T 06-07-2017 LK06_RS12085 5f8edbe0e68d21ededf08cc6acc42ef4 408 Gene3D G3DSA:3.30.70.360 222 322 3.9E-29 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS12000 ad800c9fd35c24c498aa44dea3f310a7 129 Gene3D G3DSA:3.10.180.10 5 128 3.4E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS12000 ad800c9fd35c24c498aa44dea3f310a7 129 SUPERFAMILY SSF54593 2 128 1.65E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS04890 7ec0b07fd1bd23acfb7a28c66298ba87 385 Pfam PF03595 Voltage-dependent anion channel 19 353 5.6E-59 T 06-07-2017 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 LK06_RS28780 d932fee4004044cd1acf2606a1ad5abc 265 Gene3D G3DSA:3.90.190.10 132 192 5.7E-19 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like LK06_RS28780 d932fee4004044cd1acf2606a1ad5abc 265 Gene3D G3DSA:3.90.190.10 13 97 5.7E-19 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like LK06_RS28780 d932fee4004044cd1acf2606a1ad5abc 265 SUPERFAMILY SSF52799 11 264 2.95E-48 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like LK06_RS28780 d932fee4004044cd1acf2606a1ad5abc 265 Pfam PF13350 Tyrosine phosphatase family 11 264 1.8E-64 T 06-07-2017 IPR026893 Tyrosine/serine-protein phosphatase IphP-type LK06_RS04260 247281a315e55fcbc3caccfc924d780f 182 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 12 171 1.7E-59 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 LK06_RS04260 247281a315e55fcbc3caccfc924d780f 182 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 11 182 35.855 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 LK06_RS04260 247281a315e55fcbc3caccfc924d780f 182 Pfam PF00156 Phosphoribosyl transferase domain 34 157 1.8E-15 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 LK06_RS04260 247281a315e55fcbc3caccfc924d780f 182 Gene3D G3DSA:3.40.50.2020 9 169 2.6E-61 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS04260 247281a315e55fcbc3caccfc924d780f 182 SUPERFAMILY SSF53271 13 169 7.08E-48 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 SUPERFAMILY SSF47384 139 220 4.12E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 SUPERFAMILY SSF55874 209 374 8.38E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 Gene3D G3DSA:3.30.565.10 205 374 2.5E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 SMART SM00388 151 219 2.5E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 Gene3D G3DSA:1.10.287.130 143 204 1.2E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 265 374 5.6E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 334 2.3E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 373 2.3E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 354 2.3E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 320 2.3E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 Pfam PF00512 His Kinase A (phospho-acceptor) domain 153 219 2.3E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 SUPERFAMILY SSF55785 36 125 4.19E-10 T 06-07-2017 IPR000014 PAS domain LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 SMART SM00387 264 376 4.6E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 Gene3D G3DSA:3.30.450.20 36 89 3.5E-11 T 06-07-2017 LK06_RS04800 cb7092b667da5b1b14296a6160f7b011 381 Pfam PF08448 PAS fold 36 147 5.2E-8 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS11460 fe74f5cc619c69ced74c056e6e16bdfe 199 SUPERFAMILY SSF160904 13 193 3.14E-40 T 06-07-2017 LK06_RS11460 fe74f5cc619c69ced74c056e6e16bdfe 199 Gene3D G3DSA:1.10.3300.10 14 194 1.3E-42 T 06-07-2017 IPR023286 ABATE domain LK06_RS11460 fe74f5cc619c69ced74c056e6e16bdfe 199 Pfam PF11706 CGNR zinc finger 152 194 7.8E-17 T 06-07-2017 IPR021005 Zinc finger, CGNR LK06_RS11460 fe74f5cc619c69ced74c056e6e16bdfe 199 Pfam PF07336 Putative stress-induced transcription regulator 18 146 1.0E-24 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator LK06_RS03310 4a122f16391a4c895da65b5e0818daa5 156 SUPERFAMILY SSF50475 8 151 8.57E-32 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS03310 4a122f16391a4c895da65b5e0818daa5 156 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 101 2.2E-19 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS03310 4a122f16391a4c895da65b5e0818daa5 156 Gene3D G3DSA:2.30.110.10 11 152 2.1E-37 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS00630 334c5a636d6b3f0787974740657ba8fa 385 SUPERFAMILY SSF51905 272 355 4.05E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS00630 334c5a636d6b3f0787974740657ba8fa 385 SUPERFAMILY SSF51905 1 164 4.05E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS00630 334c5a636d6b3f0787974740657ba8fa 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 2.0E-12 T 06-07-2017 LK06_RS00630 334c5a636d6b3f0787974740657ba8fa 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 2.0E-12 T 06-07-2017 LK06_RS00630 334c5a636d6b3f0787974740657ba8fa 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 2.0E-12 T 06-07-2017 LK06_RS00630 334c5a636d6b3f0787974740657ba8fa 385 Pfam PF01494 FAD binding domain 1 337 8.5E-22 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS00630 334c5a636d6b3f0787974740657ba8fa 385 Gene3D G3DSA:3.50.50.60 1 169 3.0E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS00630 334c5a636d6b3f0787974740657ba8fa 385 Gene3D G3DSA:3.50.50.60 265 343 3.0E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS23230 91651a75c71ca48f4b94b240a7b69ff9 378 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 115 272 5.9E-55 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS23230 91651a75c71ca48f4b94b240a7b69ff9 378 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 116 272 2.0E-49 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS05215 5fce76a947b50a21f852c2730282785e 433 Gene3D G3DSA:3.40.50.2020 2 60 2.4E-39 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS05215 5fce76a947b50a21f852c2730282785e 433 Gene3D G3DSA:3.40.50.2020 92 203 2.4E-39 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS05215 5fce76a947b50a21f852c2730282785e 433 Gene3D G3DSA:3.40.50.1820 223 428 7.7E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS05215 5fce76a947b50a21f852c2730282785e 433 Pfam PF01738 Dienelactone hydrolase family 301 417 2.5E-4 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 LK06_RS05215 5fce76a947b50a21f852c2730282785e 433 Pfam PF00156 Phosphoribosyl transferase domain 11 193 9.8E-24 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 LK06_RS05215 5fce76a947b50a21f852c2730282785e 433 SUPERFAMILY SSF53474 196 428 7.65E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS05215 5fce76a947b50a21f852c2730282785e 433 SUPERFAMILY SSF53271 1 208 6.39E-50 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS27720 6bbefab8767484477d119d5a8dd18e6e 454 Gene3D G3DSA:3.30.830.10 12 233 8.6E-37 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 LK06_RS27720 6bbefab8767484477d119d5a8dd18e6e 454 Gene3D G3DSA:3.30.830.10 267 438 7.4E-5 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 LK06_RS27720 6bbefab8767484477d119d5a8dd18e6e 454 Pfam PF00675 Insulinase (Peptidase family M16) 27 141 2.2E-9 T 06-07-2017 IPR011765 Peptidase M16, N-terminal LK06_RS27720 6bbefab8767484477d119d5a8dd18e6e 454 Pfam PF05193 Peptidase M16 inactive domain 181 372 3.5E-15 T 06-07-2017 IPR007863 Peptidase M16, C-terminal LK06_RS27720 6bbefab8767484477d119d5a8dd18e6e 454 SUPERFAMILY SSF63411 16 231 1.01E-36 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LK06_RS27720 6bbefab8767484477d119d5a8dd18e6e 454 SUPERFAMILY SSF63411 260 439 5.24E-11 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LK06_RS15605 809e00166cd45f47713df641abaea853 212 Gene3D G3DSA:3.40.50.880 4 191 5.2E-66 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS15605 809e00166cd45f47713df641abaea853 212 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 188 4.8E-61 T 06-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 2.1E-8 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 2.1E-8 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00097 Anthranilate synthase component II signature 122 134 8.9E-34 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00097 Anthranilate synthase component II signature 167 180 8.9E-34 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00097 Anthranilate synthase component II signature 49 58 8.9E-34 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00097 Anthranilate synthase component II signature 5 19 8.9E-34 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00097 Anthranilate synthase component II signature 102 110 8.9E-34 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00097 Anthranilate synthase component II signature 77 88 8.9E-34 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 SUPERFAMILY SSF52317 4 191 2.07E-55 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 2.3E-13 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 2.3E-13 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 2.3E-13 T 06-07-2017 LK06_RS15605 809e00166cd45f47713df641abaea853 212 Pfam PF00117 Glutamine amidotransferase class-I 7 189 6.0E-52 T 06-07-2017 IPR017926 Glutamine amidotransferase LK06_RS15190 8217ba369542f7b4eb743f198b06be00 224 Gene3D G3DSA:3.40.50.720 7 182 6.5E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15190 8217ba369542f7b4eb743f198b06be00 224 Pfam PF00106 short chain dehydrogenase 7 181 1.2E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS15190 8217ba369542f7b4eb743f198b06be00 224 SUPERFAMILY SSF51735 7 190 1.82E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00100 11ac2a06b41da4a10fac39697303f1fb 731 Pfam PF03176 MMPL family 43 366 6.1E-67 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS00100 11ac2a06b41da4a10fac39697303f1fb 731 Pfam PF03176 MMPL family 399 696 1.4E-53 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS00100 11ac2a06b41da4a10fac39697303f1fb 731 SUPERFAMILY SSF82866 132 341 1.57E-31 T 06-07-2017 LK06_RS00100 11ac2a06b41da4a10fac39697303f1fb 731 SUPERFAMILY SSF82866 454 690 2.35E-34 T 06-07-2017 LK06_RS00100 11ac2a06b41da4a10fac39697303f1fb 731 Gene3D G3DSA:1.20.1640.10 477 693 1.8E-31 T 06-07-2017 LK06_RS00100 11ac2a06b41da4a10fac39697303f1fb 731 Gene3D G3DSA:1.20.1640.10 132 345 3.8E-34 T 06-07-2017 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00385 P450 superfamily signature 350 359 7.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00385 P450 superfamily signature 359 370 7.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00385 P450 superfamily signature 285 296 7.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00385 P450 superfamily signature 250 267 7.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00359 B-class P450 signature 93 104 4.3E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00359 B-class P450 signature 158 173 4.3E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00359 B-class P450 signature 330 345 4.3E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00359 B-class P450 signature 141 157 4.3E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00359 B-class P450 signature 201 223 4.3E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00359 B-class P450 signature 285 296 4.3E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00359 B-class P450 signature 302 329 4.3E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00359 B-class P450 signature 350 359 4.3E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 PRINTS PR00359 B-class P450 signature 359 370 4.3E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 SUPERFAMILY SSF48264 19 406 1.14E-64 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 Pfam PF00067 Cytochrome P450 282 379 5.9E-20 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 Gene3D G3DSA:1.10.630.10 16 407 1.8E-81 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14910 0161ebe84b802a8ea1d600c1afcf8c63 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS04575 018851aca8b6491a1918972a58584130 402 Pfam PF13649 Methyltransferase domain 257 320 8.5E-7 T 06-07-2017 LK06_RS04575 018851aca8b6491a1918972a58584130 402 Gene3D G3DSA:3.40.50.150 244 369 2.8E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS04575 018851aca8b6491a1918972a58584130 402 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 9 196 2.4E-36 T 06-07-2017 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 LK06_RS04575 018851aca8b6491a1918972a58584130 402 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 183 7.3E-18 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS04575 018851aca8b6491a1918972a58584130 402 Gene3D G3DSA:3.40.1010.10 5 103 9.5E-17 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS04575 018851aca8b6491a1918972a58584130 402 SUPERFAMILY SSF53335 235 373 8.27E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS04575 018851aca8b6491a1918972a58584130 402 Gene3D G3DSA:3.30.950.10 104 197 1.0E-17 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS04575 018851aca8b6491a1918972a58584130 402 PIRSF PIRSF036428 1 395 9.7E-93 T 06-07-2017 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 LK06_RS04575 018851aca8b6491a1918972a58584130 402 SUPERFAMILY SSF53790 8 197 2.09E-31 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 33 435 4.6E-117 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 Gene3D G3DSA:3.40.50.980 165 323 2.7E-44 T 06-07-2017 LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 Gene3D G3DSA:3.30.300.30 749 811 8.7E-31 T 06-07-2017 LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 Gene3D G3DSA:3.30.300.30 406 460 8.7E-31 T 06-07-2017 LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 ProSitePatterns PS00012 Phosphopantetheine attachment site. 225 240 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 Pfam PF00501 AMP-binding enzyme 15 411 7.2E-93 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 ProSitePatterns PS00012 Phosphopantetheine attachment site. 831 846 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 Pfam PF00550 Phosphopantetheine attachment site 808 870 3.3E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 Gene3D G3DSA:2.30.38.10 324 400 8.0E-22 T 06-07-2017 LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 508 684 7.3E-31 T 06-07-2017 IPR006342 Methyltransferase FkbM LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 Gene3D G3DSA:3.40.50.150 491 717 5.6E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 SUPERFAMILY SSF53335 480 590 3.16E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 SUPERFAMILY SSF53335 630 712 3.16E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 SUPERFAMILY SSF47336 802 871 7.98E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 Pfam PF05050 Methyltransferase FkbM domain 511 704 1.1E-15 T 06-07-2017 IPR006342 Methyltransferase FkbM LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 Gene3D G3DSA:1.10.1200.10 812 872 2.4E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 SUPERFAMILY SSF56801 744 820 8.82E-145 T 06-07-2017 LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 SUPERFAMILY SSF56801 5 465 8.82E-145 T 06-07-2017 LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS03275 dd3987bc18234ba89538103d23c32a4b 881 Gene3D G3DSA:3.40.50.980 12 164 5.3E-34 T 06-07-2017 LK06_RS04190 ed0672b9d308556593aec5a467392068 154 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 140 22.94 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 LK06_RS04190 ed0672b9d308556593aec5a467392068 154 Gene3D G3DSA:3.30.420.140 3 142 3.8E-47 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 LK06_RS04190 ed0672b9d308556593aec5a467392068 154 Pfam PF03652 Holliday junction resolvase 5 137 4.0E-43 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 LK06_RS04190 ed0672b9d308556593aec5a467392068 154 SMART SM00732 4 105 2.4E-32 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 LK06_RS04190 ed0672b9d308556593aec5a467392068 154 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 8 137 6.2E-32 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 LK06_RS04190 ed0672b9d308556593aec5a467392068 154 SUPERFAMILY SSF53098 4 138 2.12E-35 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 SMART SM00632 401 478 2.5E-14 T 06-07-2017 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 SMART SM01065 493 585 3.3E-26 T 06-07-2017 IPR002044 Carbohydrate binding module family 20 GO:2001070 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 SMART SM01065 593 685 2.1E-27 T 06-07-2017 IPR002044 Carbohydrate binding module family 20 GO:2001070 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 Gene3D G3DSA:3.20.20.80 40 395 1.1E-82 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 SUPERFAMILY SSF49452 595 687 1.15E-27 T 06-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 SMART SM00642 44 392 8.5E-51 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 Gene3D G3DSA:2.60.40.10 492 578 2.6E-27 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 406 474 6.1E-9 T 06-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 Pfam PF00686 Starch binding domain 594 683 2.1E-27 T 06-07-2017 IPR002044 Carbohydrate binding module family 20 GO:2001070 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 Pfam PF00686 Starch binding domain 494 578 3.9E-26 T 06-07-2017 IPR002044 Carbohydrate binding module family 20 GO:2001070 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 Pfam PF00128 Alpha amylase, catalytic domain 72 325 1.0E-20 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 SUPERFAMILY SSF49452 492 578 4.66E-27 T 06-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 PRINTS PR00110 Alpha-amylase signature 216 227 2.9E-16 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 PRINTS PR00110 Alpha-amylase signature 303 315 2.9E-16 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 PRINTS PR00110 Alpha-amylase signature 89 106 2.9E-16 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 PRINTS PR00110 Alpha-amylase signature 121 132 2.9E-16 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 SUPERFAMILY SSF51445 41 381 5.28E-70 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 SUPERFAMILY SSF51011 399 474 3.77E-17 T 06-07-2017 LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 Gene3D G3DSA:2.60.40.10 593 688 8.6E-28 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS08095 a6e1932db119ae144e1898c26e5e245f 688 Gene3D G3DSA:2.60.40.1180 399 474 1.2E-22 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS16655 25adb5b1845ae9cd06e864325896776b 164 Gene3D G3DSA:1.10.10.10 30 138 1.4E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16655 25adb5b1845ae9cd06e864325896776b 164 SMART SM00347 26 125 1.0E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS16655 25adb5b1845ae9cd06e864325896776b 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 9.6E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS16655 25adb5b1845ae9cd06e864325896776b 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 9.6E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS16655 25adb5b1845ae9cd06e864325896776b 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 9.6E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS16655 25adb5b1845ae9cd06e864325896776b 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 9.6E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS16655 25adb5b1845ae9cd06e864325896776b 164 SUPERFAMILY SSF46785 31 141 2.68E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16655 25adb5b1845ae9cd06e864325896776b 164 Pfam PF01047 MarR family 38 89 1.6E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29840 c0d0a00972e5b86e6bc004f67e9082d7 364 Gene3D G3DSA:2.130.10.10 9 361 1.7E-81 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS29840 c0d0a00972e5b86e6bc004f67e9082d7 364 SUPERFAMILY SSF110296 7 361 5.62E-60 T 06-07-2017 LK06_RS24375 610048fd1edac28203ccc5ae2039a5de 446 SUPERFAMILY SSF111352 15 399 3.01E-122 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 LK06_RS24375 610048fd1edac28203ccc5ae2039a5de 446 ProSitePatterns PS01219 Ammonium transporters signature. 172 197 - T 06-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 LK06_RS24375 610048fd1edac28203ccc5ae2039a5de 446 Pfam PF00909 Ammonium Transporter Family 21 418 5.4E-126 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 LK06_RS24375 610048fd1edac28203ccc5ae2039a5de 446 TIGRFAM TIGR00836 amt: ammonium transporter 18 418 3.4E-135 T 06-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 LK06_RS24375 610048fd1edac28203ccc5ae2039a5de 446 Gene3D G3DSA:1.10.3430.10 14 399 3.6E-131 T 06-07-2017 IPR029020 Ammonium/urea transporter LK06_RS04870 e2ba0d34c6c4c8a5359e5c7fa482f013 456 SMART SM01230 120 374 6.0E-100 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS04870 e2ba0d34c6c4c8a5359e5c7fa482f013 456 Pfam PF00120 Glutamine synthetase, catalytic domain 122 451 2.5E-102 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS04870 e2ba0d34c6c4c8a5359e5c7fa482f013 456 SUPERFAMILY SSF54368 10 119 5.89E-18 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS04870 e2ba0d34c6c4c8a5359e5c7fa482f013 456 Gene3D G3DSA:3.30.590.10 123 443 8.7E-98 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LK06_RS04870 e2ba0d34c6c4c8a5359e5c7fa482f013 456 SUPERFAMILY SSF55931 122 454 9.12E-101 T 06-07-2017 LK06_RS04870 e2ba0d34c6c4c8a5359e5c7fa482f013 456 Gene3D G3DSA:3.10.20.70 10 122 1.8E-10 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08650 d2b5c6a87fdd59484cf4cb7f652add3c 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 16 188 5.1E-20 T 06-07-2017 IPR023214 HAD-like domain LK06_RS08650 d2b5c6a87fdd59484cf4cb7f652add3c 222 Gene3D G3DSA:1.10.150.240 29 68 6.5E-5 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 LK06_RS08650 d2b5c6a87fdd59484cf4cb7f652add3c 222 Gene3D G3DSA:3.40.50.1000 80 215 5.7E-38 T 06-07-2017 IPR023214 HAD-like domain LK06_RS08650 d2b5c6a87fdd59484cf4cb7f652add3c 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 95 188 4.5E-17 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS08650 d2b5c6a87fdd59484cf4cb7f652add3c 222 ProSitePatterns PS01228 Hypothetical cof family signature 1. 14 25 - T 06-07-2017 IPR000150 Cof protein GO:0016787 LK06_RS08650 d2b5c6a87fdd59484cf4cb7f652add3c 222 SUPERFAMILY SSF56784 13 207 1.2E-40 T 06-07-2017 IPR023214 HAD-like domain LK06_RS06670 cb716d4d50e8d4bb30e661b62b2abfd8 229 Pfam PF07398 MDMPI C-terminal domain 147 217 1.2E-7 T 06-07-2017 IPR010872 MDMPI C-terminal LK06_RS06670 cb716d4d50e8d4bb30e661b62b2abfd8 229 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 140 1.8E-19 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 LK06_RS06670 cb716d4d50e8d4bb30e661b62b2abfd8 229 SUPERFAMILY SSF55718 148 228 1.09E-18 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS06670 cb716d4d50e8d4bb30e661b62b2abfd8 229 SUPERFAMILY SSF109854 1 146 1.74E-37 T 06-07-2017 LK06_RS06670 cb716d4d50e8d4bb30e661b62b2abfd8 229 Gene3D G3DSA:1.20.120.450 12 113 8.1E-5 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase LK06_RS06670 cb716d4d50e8d4bb30e661b62b2abfd8 229 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 210 1.8E-39 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 SUPERFAMILY SSF81296 939 1062 9.66E-35 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 1071 1149 3.4E-9 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 SUPERFAMILY SSF51011 1705 1795 7.55E-26 T 06-07-2017 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 SMART SM00642 66 523 4.0E-94 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Gene3D G3DSA:2.60.40.1180 534 614 1.2E-10 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Pfam PF00128 Alpha amylase, catalytic domain 104 471 9.3E-98 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Pfam PF11852 Domain of unknown function (DUF3372) 1647 1794 6.4E-43 T 06-07-2017 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Gene3D G3DSA:3.20.20.80 250 533 5.8E-96 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Gene3D G3DSA:3.20.20.80 64 68 5.8E-96 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Gene3D G3DSA:3.20.20.80 103 218 5.8E-96 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 SUPERFAMILY SSF49452 835 936 8.5E-32 T 06-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 944 1795 1.8E-304 T 06-07-2017 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Gene3D G3DSA:2.60.40.10 1072 1163 6.6E-15 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 SUPERFAMILY SSF51011 538 613 8.39E-6 T 06-07-2017 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Pfam PF03714 Bacterial pullanase-associated domain 840 930 1.7E-22 T 06-07-2017 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Pfam PF03714 Bacterial pullanase-associated domain 731 826 1.5E-23 T 06-07-2017 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 SUPERFAMILY SSF51445 58 192 1.79E-92 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 SUPERFAMILY SSF51445 238 532 1.79E-92 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 SUPERFAMILY SSF51445 1161 1704 1.63E-121 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Gene3D G3DSA:3.20.20.80 1526 1643 4.0E-81 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Gene3D G3DSA:3.20.20.80 1677 1704 4.0E-81 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Gene3D G3DSA:3.20.20.80 1178 1479 4.0E-81 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 SUPERFAMILY SSF81296 1070 1166 5.8E-19 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 SUPERFAMILY SSF49452 728 830 2.39E-30 T 06-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 LK06_RS08090 a2406f67aa06f5134ec8c1078e061273 1798 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 542 615 4.0E-4 T 06-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 LK06_RS13570 2942f0b0b9298e4f660faf49a8df4508 272 Pfam PF01261 Xylose isomerase-like TIM barrel 19 206 6.4E-18 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS13570 2942f0b0b9298e4f660faf49a8df4508 272 Gene3D G3DSA:3.20.20.150 1 255 1.4E-46 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS13570 2942f0b0b9298e4f660faf49a8df4508 272 SUPERFAMILY SSF51658 2 259 3.27E-45 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS31260 f79339e75805fa48975b00b7a6ddb07d 241 Gene3D G3DSA:3.40.50.300 31 150 2.0E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31260 f79339e75805fa48975b00b7a6ddb07d 241 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 33 195 5.3E-21 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain LK06_RS31260 f79339e75805fa48975b00b7a6ddb07d 241 SUPERFAMILY SSF52540 7 213 5.11E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31260 f79339e75805fa48975b00b7a6ddb07d 241 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 3 210 1.3E-65 T 06-07-2017 IPR004392 Hydrogenase accessory protein HypB GO:0006461|GO:0016151 LK06_RS31260 f79339e75805fa48975b00b7a6ddb07d 241 PIRSF PIRSF005624 2 223 4.3E-77 T 06-07-2017 LK06_RS18410 784b5f4ab171742d82225dacbd7c49c4 239 Pfam PF03932 CutC family 7 202 4.5E-25 T 06-07-2017 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 LK06_RS18410 784b5f4ab171742d82225dacbd7c49c4 239 Gene3D G3DSA:3.20.20.380 5 211 4.1E-47 T 06-07-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 LK06_RS18410 784b5f4ab171742d82225dacbd7c49c4 239 SUPERFAMILY SSF110395 6 228 3.66E-42 T 06-07-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 LK06_RS24250 5de81d9850e08b3c8994d9eb8157e84c 560 SUPERFAMILY SSF101473 10 217 2.75E-31 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 LK06_RS24250 5de81d9850e08b3c8994d9eb8157e84c 560 Pfam PF13684 Dihydroxyacetone kinase family 257 560 5.2E-78 T 06-07-2017 IPR033470 Uncharacterised protein, DhaK domain LK06_RS24250 5de81d9850e08b3c8994d9eb8157e84c 560 Pfam PF02734 DAK2 domain 39 214 1.3E-27 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 LK06_RS24250 5de81d9850e08b3c8994d9eb8157e84c 560 SMART SM01120 39 215 4.0E-42 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 LK06_RS24250 5de81d9850e08b3c8994d9eb8157e84c 560 SMART SM01121 255 560 1.9E-99 T 06-07-2017 IPR033470 Uncharacterised protein, DhaK domain LK06_RS24250 5de81d9850e08b3c8994d9eb8157e84c 560 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 15 560 2.6E-134 T 06-07-2017 IPR019986 DAK2 domain-containing protein YloV LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 Pfam PF00067 Cytochrome P450 282 403 1.8E-22 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 Pfam PF00067 Cytochrome P450 86 275 1.8E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 Gene3D G3DSA:1.10.630.10 14 408 8.5E-118 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00385 P450 superfamily signature 282 293 1.5E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00385 P450 superfamily signature 349 358 1.5E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00385 P450 superfamily signature 358 369 1.5E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00385 P450 superfamily signature 247 264 1.5E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00359 B-class P450 signature 201 223 5.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00359 B-class P450 signature 154 169 5.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00359 B-class P450 signature 358 369 5.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00359 B-class P450 signature 87 98 5.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00359 B-class P450 signature 282 293 5.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00359 B-class P450 signature 300 327 5.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00359 B-class P450 signature 328 343 5.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00359 B-class P450 signature 349 358 5.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 PRINTS PR00359 B-class P450 signature 137 153 5.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02905 4b624f997af3683ee57ad771b6df7df1 411 SUPERFAMILY SSF48264 14 407 3.93E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 SUPERFAMILY SSF49785 78 198 8.51E-16 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 Pfam PF07971 Glycosyl hydrolase family 92 588 1109 3.2E-140 T 06-07-2017 IPR012939 Glycosyl hydrolase family 92 LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 381 1112 7.4E-140 T 06-07-2017 IPR005887 Alpha-1,2-mannosidase, putative LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 Pfam PF00754 F5/8 type C domain 73 194 1.7E-12 T 06-07-2017 IPR000421 Coagulation factor 5/8 C-terminal domain LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 Gene3D G3DSA:1.20.1050.60 710 797 3.6E-28 T 06-07-2017 LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 Gene3D G3DSA:2.60.120.260 72 198 2.9E-16 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 Gene3D G3DSA:2.70.98.10 382 669 2.5E-75 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 Gene3D G3DSA:3.30.2080.10 972 1120 1.3E-58 T 06-07-2017 LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 SUPERFAMILY SSF48208 703 1093 4.25E-14 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 SUPERFAMILY SSF48208 614 666 4.25E-14 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS26525 6294156d64d925d44831509b984b33f2 1247 Gene3D G3DSA:1.20.1610.10 802 971 1.1E-47 T 06-07-2017 LK06_RS28500 f80f3220e80349e304413f6f1b368922 682 Pfam PF05506 Domain of unknown function (DUF756) 596 666 4.8E-13 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 LK06_RS28500 f80f3220e80349e304413f6f1b368922 682 Pfam PF05506 Domain of unknown function (DUF756) 495 582 1.2E-19 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 LK06_RS28500 f80f3220e80349e304413f6f1b368922 682 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 680 2.9E-254 T 06-07-2017 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 LK06_RS28500 f80f3220e80349e304413f6f1b368922 682 Pfam PF04185 Phosphoesterase family 44 427 1.4E-116 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 LK06_RS01310 6d24b345393ec963821cbb2565375d4f 288 Gene3D G3DSA:3.40.50.300 32 212 1.4E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01310 6d24b345393ec963821cbb2565375d4f 288 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 37 186 9.4E-11 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS01310 6d24b345393ec963821cbb2565375d4f 288 SUPERFAMILY SSF52540 28 272 4.88E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01310 6d24b345393ec963821cbb2565375d4f 288 SMART SM00382 33 197 6.6E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 5.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 5.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 Gene3D G3DSA:3.40.50.720 4 250 1.0E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 SUPERFAMILY SSF51735 5 250 7.16E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 1.5E-63 T 06-07-2017 LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 2.9E-6 T 06-07-2017 LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS03145 c0a995335e21c1a615e391e28c05ddfe 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS00945 5c8cc0cca0f2c44e0693f803a4e371ef 122 SUPERFAMILY SSF54427 26 115 4.12E-11 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS00945 5c8cc0cca0f2c44e0693f803a4e371ef 122 Gene3D G3DSA:3.10.450.50 26 113 4.1E-8 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS00945 5c8cc0cca0f2c44e0693f803a4e371ef 122 Pfam PF12680 SnoaL-like domain 26 113 5.6E-9 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain LK06_RS11640 fc792d44896172a2b524f64dfbcec797 750 SUPERFAMILY SSF53756 517 723 2.2E-15 T 06-07-2017 LK06_RS11640 fc792d44896172a2b524f64dfbcec797 750 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 360 724 4.3E-107 T 06-07-2017 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 LK06_RS11640 fc792d44896172a2b524f64dfbcec797 750 SUPERFAMILY SSF53448 2 243 1.22E-49 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11640 fc792d44896172a2b524f64dfbcec797 750 Pfam PF00535 Glycosyl transferase family 2 5 110 1.7E-33 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS11640 fc792d44896172a2b524f64dfbcec797 750 Gene3D G3DSA:3.90.550.10 2 247 1.3E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS27440 42e03a54e901ecd93b21147d6aebc825 402 Pfam PF00155 Aminotransferase class I and II 34 390 3.4E-49 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS27440 42e03a54e901ecd93b21147d6aebc825 402 Gene3D G3DSA:3.90.1150.10 278 401 3.1E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS27440 42e03a54e901ecd93b21147d6aebc825 402 Gene3D G3DSA:3.40.640.10 50 277 1.6E-67 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS27440 42e03a54e901ecd93b21147d6aebc825 402 SUPERFAMILY SSF53383 4 398 4.71E-94 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS12695 ac9dfb6bcb2588867554375174d13e96 223 Pfam PF00072 Response regulator receiver domain 7 117 1.2E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS12695 ac9dfb6bcb2588867554375174d13e96 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 204 6.7E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS12695 ac9dfb6bcb2588867554375174d13e96 223 SUPERFAMILY SSF52172 2 177 5.47E-15 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS12695 ac9dfb6bcb2588867554375174d13e96 223 SMART SM00421 157 219 4.8E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS12695 ac9dfb6bcb2588867554375174d13e96 223 Gene3D G3DSA:3.40.50.2300 2 157 1.3E-23 T 06-07-2017 LK06_RS12695 ac9dfb6bcb2588867554375174d13e96 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 3.4E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS12695 ac9dfb6bcb2588867554375174d13e96 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 3.4E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS12695 ac9dfb6bcb2588867554375174d13e96 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 3.4E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS12695 ac9dfb6bcb2588867554375174d13e96 223 SMART SM00448 5 129 1.9E-7 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS12695 ac9dfb6bcb2588867554375174d13e96 223 Gene3D G3DSA:1.10.10.10 158 222 9.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11275 4a4c2ccfaf53b83689fa6329c700e703 249 Pfam PF06271 RDD family 106 242 3.5E-26 T 06-07-2017 IPR010432 RDD LK06_RS11275 4a4c2ccfaf53b83689fa6329c700e703 249 SUPERFAMILY SSF81995 24 95 9.94E-5 T 06-07-2017 LK06_RS11290 0173964fe6db4997d6464d42e74f8ba0 468 SUPERFAMILY SSF56176 16 229 1.45E-70 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS11290 0173964fe6db4997d6464d42e74f8ba0 468 SUPERFAMILY SSF55103 204 467 1.42E-63 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LK06_RS11290 0173964fe6db4997d6464d42e74f8ba0 468 Gene3D G3DSA:1.10.45.10 428 467 7.2E-16 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 LK06_RS11290 0173964fe6db4997d6464d42e74f8ba0 468 Pfam PF02913 FAD linked oxidases, C-terminal domain 229 467 1.4E-67 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LK06_RS11290 0173964fe6db4997d6464d42e74f8ba0 468 Pfam PF01565 FAD binding domain 53 192 2.8E-40 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LK06_RS11290 0173964fe6db4997d6464d42e74f8ba0 468 Gene3D G3DSA:3.30.465.10 109 229 4.2E-43 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS11290 0173964fe6db4997d6464d42e74f8ba0 468 Gene3D G3DSA:3.30.43.10 11 108 1.8E-26 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS02560 6d46370c40165659b37688691ec12f76 285 Pfam PF12833 Helix-turn-helix domain 30 108 1.2E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS02560 6d46370c40165659b37688691ec12f76 285 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 61 103 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LK06_RS02560 6d46370c40165659b37688691ec12f76 285 SUPERFAMILY SSF46689 10 57 4.48E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02560 6d46370c40165659b37688691ec12f76 285 SMART SM00342 24 107 3.3E-32 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS02560 6d46370c40165659b37688691ec12f76 285 Gene3D G3DSA:1.10.10.60 10 61 2.7E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02560 6d46370c40165659b37688691ec12f76 285 SUPERFAMILY SSF46689 60 108 2.06E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02560 6d46370c40165659b37688691ec12f76 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 91 107 5.2E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LK06_RS02560 6d46370c40165659b37688691ec12f76 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 76 91 5.2E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LK06_RS02560 6d46370c40165659b37688691ec12f76 285 Gene3D G3DSA:1.10.10.60 62 108 3.3E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS07575 3757e658295e870c382abb900d381f17 313 Gene3D G3DSA:3.90.1720.10 196 303 5.6E-42 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS07575 3757e658295e870c382abb900d381f17 313 Pfam PF00877 NlpC/P60 family 214 301 3.2E-26 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS07575 3757e658295e870c382abb900d381f17 313 SUPERFAMILY SSF54001 196 303 5.4E-39 T 06-07-2017 LK06_RS06095 1b2d474874d1fd304569e67d1f7b19b4 428 Gene3D G3DSA:3.20.20.140 10 375 2.4E-52 T 06-07-2017 LK06_RS06095 1b2d474874d1fd304569e67d1f7b19b4 428 SUPERFAMILY SSF51556 8 37 8.32E-57 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS06095 1b2d474874d1fd304569e67d1f7b19b4 428 SUPERFAMILY SSF51556 68 374 8.32E-57 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS06095 1b2d474874d1fd304569e67d1f7b19b4 428 Pfam PF04909 Amidohydrolase 14 373 9.3E-24 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS21790 ff5df78b0a1fdf2d345c804c7ed9efa0 256 Pfam PF13183 4Fe-4S dicluster domain 141 222 1.5E-14 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LK06_RS21790 ff5df78b0a1fdf2d345c804c7ed9efa0 256 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 105 1.1E-25 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS21790 ff5df78b0a1fdf2d345c804c7ed9efa0 256 SUPERFAMILY SSF54292 7 104 1.07E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS21790 ff5df78b0a1fdf2d345c804c7ed9efa0 256 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 54 62 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LK06_RS21790 ff5df78b0a1fdf2d345c804c7ed9efa0 256 SUPERFAMILY SSF46548 122 235 5.58E-18 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 LK06_RS21790 ff5df78b0a1fdf2d345c804c7ed9efa0 256 Gene3D G3DSA:3.10.20.30 5 96 6.5E-29 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS21790 ff5df78b0a1fdf2d345c804c7ed9efa0 256 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 18 225 6.2E-41 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS21790 ff5df78b0a1fdf2d345c804c7ed9efa0 256 Gene3D G3DSA:1.10.1060.10 97 244 1.9E-18 T 06-07-2017 LK06_RS10745 1efb21e059e9809f1f0c47c533680aff 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 341 356 3.0E-7 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 LK06_RS10745 1efb21e059e9809f1f0c47c533680aff 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 80 99 3.0E-7 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 LK06_RS10745 1efb21e059e9809f1f0c47c533680aff 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 384 403 3.0E-7 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 LK06_RS10745 1efb21e059e9809f1f0c47c533680aff 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 120 139 3.0E-7 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 LK06_RS10745 1efb21e059e9809f1f0c47c533680aff 480 Gene3D G3DSA:3.40.640.10 90 355 3.8E-92 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS10745 1efb21e059e9809f1f0c47c533680aff 480 SUPERFAMILY SSF53383 33 471 1.33E-116 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS10745 1efb21e059e9809f1f0c47c533680aff 480 Gene3D G3DSA:3.90.1150.10 356 471 9.5E-42 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS10745 1efb21e059e9809f1f0c47c533680aff 480 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 59 402 1.0E-59 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 LK06_RS10745 1efb21e059e9809f1f0c47c533680aff 480 Gene3D G3DSA:1.20.1650.10 4 79 2.5E-23 T 06-07-2017 LK06_RS03250 0d1761aa91df9b6c6985d9cd4a08abc7 436 Pfam PF05977 Transmembrane secretion effector 15 417 2.1E-27 T 06-07-2017 IPR010290 Transmembrane secretion effector LK06_RS03250 0d1761aa91df9b6c6985d9cd4a08abc7 436 Gene3D G3DSA:1.20.1250.20 21 209 4.5E-16 T 06-07-2017 LK06_RS03250 0d1761aa91df9b6c6985d9cd4a08abc7 436 Gene3D G3DSA:1.20.1250.20 231 413 1.8E-15 T 06-07-2017 LK06_RS03250 0d1761aa91df9b6c6985d9cd4a08abc7 436 SUPERFAMILY SSF103473 21 411 1.57E-45 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS03345 2a2b56e0935667cb360c27a8df54c654 162 SUPERFAMILY SSF81923 88 152 1.31E-5 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS03345 2a2b56e0935667cb360c27a8df54c654 162 Gene3D G3DSA:1.10.1780.10 87 155 8.0E-8 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS03345 2a2b56e0935667cb360c27a8df54c654 162 Gene3D G3DSA:1.10.1780.10 1 34 4.9E-4 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS03345 2a2b56e0935667cb360c27a8df54c654 162 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 4 27 0.0086 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS03345 2a2b56e0935667cb360c27a8df54c654 162 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 117 150 0.0026 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS07020 db80578fb07c34a2d37bb2c66280c2d4 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 372 2.2E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS07020 db80578fb07c34a2d37bb2c66280c2d4 379 Gene3D G3DSA:2.40.110.10 123 221 6.4E-24 T 06-07-2017 LK06_RS07020 db80578fb07c34a2d37bb2c66280c2d4 379 SUPERFAMILY SSF56645 2 242 2.23E-57 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS07020 db80578fb07c34a2d37bb2c66280c2d4 379 Gene3D G3DSA:1.10.540.10 2 121 8.5E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS07020 db80578fb07c34a2d37bb2c66280c2d4 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 1.4E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS07020 db80578fb07c34a2d37bb2c66280c2d4 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 219 7.1E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS07020 db80578fb07c34a2d37bb2c66280c2d4 379 Gene3D G3DSA:1.20.140.10 222 377 3.8E-30 T 06-07-2017 LK06_RS07020 db80578fb07c34a2d37bb2c66280c2d4 379 SUPERFAMILY SSF47203 231 374 1.77E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS17795 d0189809eb626a3155d54207d1c45737 445 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 27 434 7.1E-201 T 06-07-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 LK06_RS17795 d0189809eb626a3155d54207d1c45737 445 Pfam PF00534 Glycosyl transferases group 1 238 410 1.2E-31 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS17795 d0189809eb626a3155d54207d1c45737 445 Gene3D G3DSA:3.40.50.2000 207 410 2.0E-38 T 06-07-2017 LK06_RS17795 d0189809eb626a3155d54207d1c45737 445 Pfam PF13439 Glycosyltransferase Family 4 46 227 3.1E-31 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS17795 d0189809eb626a3155d54207d1c45737 445 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 26 437 51.605 T 06-07-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 LK06_RS17795 d0189809eb626a3155d54207d1c45737 445 SUPERFAMILY SSF53756 27 430 2.44E-82 T 06-07-2017 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 57 64 2.8E-8 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 116 135 2.8E-8 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 37 47 2.8E-8 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 140 149 2.8E-8 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 SUPERFAMILY SSF63380 3 106 1.55E-25 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 Pfam PF00175 Oxidoreductase NAD-binding domain 117 213 1.3E-11 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 Gene3D G3DSA:2.40.30.10 4 98 1.3E-26 T 06-07-2017 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 SUPERFAMILY SSF52343 97 230 1.31E-31 T 06-07-2017 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 PRINTS PR00410 Phenol hydroxylase reductase family signature 200 208 2.9E-12 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 PRINTS PR00410 Phenol hydroxylase reductase family signature 116 135 2.9E-12 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 PRINTS PR00410 Phenol hydroxylase reductase family signature 37 49 2.9E-12 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 Pfam PF00970 Oxidoreductase FAD-binding domain 9 106 2.2E-11 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 LK06_RS26290 f52b97ef21ae37eaf5c03c65234d1ce4 265 Gene3D G3DSA:3.40.50.80 99 228 1.9E-31 T 06-07-2017 LK06_RS05070 c09dd2919215ff3474e2445526095ae8 282 Gene3D G3DSA:3.90.320.10 36 170 1.9E-4 T 06-07-2017 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 LK06_RS05070 c09dd2919215ff3474e2445526095ae8 282 Pfam PF12705 PD-(D/E)XK nuclease superfamily 5 253 3.1E-40 T 06-07-2017 LK06_RS05070 c09dd2919215ff3474e2445526095ae8 282 SUPERFAMILY SSF52980 30 198 2.52E-11 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LK06_RS13675 a9234f0c884b44f633b2cdc4abc45e64 131 Pfam PF03965 Penicillinase repressor 1 102 7.8E-21 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 LK06_RS13675 a9234f0c884b44f633b2cdc4abc45e64 131 Gene3D G3DSA:1.10.10.10 1 68 4.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13675 a9234f0c884b44f633b2cdc4abc45e64 131 SUPERFAMILY SSF46785 1 102 6.73E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05740 003383de26d84222dadc6bb885462256 548 Pfam PF07905 Purine catabolism regulatory protein-like family 21 141 3.4E-37 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain LK06_RS05740 003383de26d84222dadc6bb885462256 548 Gene3D G3DSA:1.10.10.60 489 521 1.4E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS05740 003383de26d84222dadc6bb885462256 548 Pfam PF13556 PucR C-terminal helix-turn-helix domain 485 543 1.5E-20 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS07065 9b9ec770a8aec9192874b44bfbecddc2 272 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 267 34.066 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LK06_RS07065 9b9ec770a8aec9192874b44bfbecddc2 272 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 15 264 4.8E-67 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LK06_RS07065 9b9ec770a8aec9192874b44bfbecddc2 272 Pfam PF00290 Tryptophan synthase alpha chain 13 266 1.2E-75 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LK06_RS07065 9b9ec770a8aec9192874b44bfbecddc2 272 SUPERFAMILY SSF51366 8 248 3.3E-78 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 LK06_RS07065 9b9ec770a8aec9192874b44bfbecddc2 272 Gene3D G3DSA:3.20.20.70 9 270 2.8E-92 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS07065 9b9ec770a8aec9192874b44bfbecddc2 272 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 52 65 - T 06-07-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LK06_RS10780 c1264da93e92d49803debbb620c94ad3 175 PRINTS PR01438 Universal stress protein signature 39 57 8.5E-7 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS10780 c1264da93e92d49803debbb620c94ad3 175 PRINTS PR01438 Universal stress protein signature 153 175 8.5E-7 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS10780 c1264da93e92d49803debbb620c94ad3 175 Gene3D G3DSA:3.40.50.620 41 175 2.3E-32 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS10780 c1264da93e92d49803debbb620c94ad3 175 Pfam PF00582 Universal stress protein family 42 175 8.6E-23 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS10780 c1264da93e92d49803debbb620c94ad3 175 SUPERFAMILY SSF52402 42 175 3.27E-21 T 06-07-2017 LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 SUPERFAMILY SSF52172 12 142 3.42E-28 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 Gene3D G3DSA:1.10.10.10 165 221 1.2E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 Pfam PF00072 Response regulator receiver domain 15 126 2.5E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 219 9.6E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 4.3E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 4.3E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 4.3E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 SMART SM00421 162 219 1.9E-26 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 SUPERFAMILY SSF46894 152 222 3.4E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 Gene3D G3DSA:3.40.50.2300 11 164 1.2E-34 T 06-07-2017 LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS00195 5c595d371ef0c4767782a2b7bf5f9f5a 233 SMART SM00448 13 126 9.0E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25160 b1e3194f6cc2fb62f0fbabc30ad7026e 635 Pfam PF05425 Copper resistance protein D 360 497 5.3E-18 T 06-07-2017 IPR008457 Copper resistance protein D GO:0016021 LK06_RS25160 b1e3194f6cc2fb62f0fbabc30ad7026e 635 Pfam PF04234 CopC domain 59 155 4.3E-23 T 06-07-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 LK06_RS25160 b1e3194f6cc2fb62f0fbabc30ad7026e 635 Gene3D G3DSA:2.60.40.1220 58 156 9.6E-26 T 06-07-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like LK06_RS25160 b1e3194f6cc2fb62f0fbabc30ad7026e 635 SUPERFAMILY SSF81296 58 156 2.38E-23 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS17275 50dfb8c745ff5992219f8a2b648f1c4a 343 Pfam PF01551 Peptidase family M23 236 328 2.8E-26 T 06-07-2017 IPR016047 Peptidase M23 LK06_RS17275 50dfb8c745ff5992219f8a2b648f1c4a 343 Gene3D G3DSA:2.70.70.10 187 337 7.0E-45 T 06-07-2017 LK06_RS17275 50dfb8c745ff5992219f8a2b648f1c4a 343 SUPERFAMILY SSF51261 147 336 3.82E-46 T 06-07-2017 IPR011055 Duplicated hybrid motif LK06_RS20550 b4a2a3fee9d4f22880e48f91f13b76d2 126 SUPERFAMILY SSF81343 2 113 5.67E-29 T 06-07-2017 LK06_RS20550 b4a2a3fee9d4f22880e48f91f13b76d2 126 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 6 110 2.5E-29 T 06-07-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20550 b4a2a3fee9d4f22880e48f91f13b76d2 126 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 5 108 5.6E-25 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20550 b4a2a3fee9d4f22880e48f91f13b76d2 126 Gene3D G3DSA:1.20.1300.10 3 113 1.6E-30 T 06-07-2017 LK06_RS25575 2d51161647ef53999a29aa7284a506e5 1067 SUPERFAMILY SSF52540 143 372 6.53E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25575 2d51161647ef53999a29aa7284a506e5 1067 Pfam PF00176 SNF2 family N-terminal domain 152 350 3.2E-10 T 06-07-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 LK06_RS25575 2d51161647ef53999a29aa7284a506e5 1067 Gene3D G3DSA:3.40.50.300 513 644 5.9E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25575 2d51161647ef53999a29aa7284a506e5 1067 SMART SM00490 553 641 3.9E-16 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS25575 2d51161647ef53999a29aa7284a506e5 1067 Gene3D G3DSA:3.40.50.300 144 334 3.8E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25575 2d51161647ef53999a29aa7284a506e5 1067 Pfam PF00271 Helicase conserved C-terminal domain 538 641 1.8E-16 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS25575 2d51161647ef53999a29aa7284a506e5 1067 SUPERFAMILY SSF52540 508 684 3.49E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25575 2d51161647ef53999a29aa7284a506e5 1067 SUPERFAMILY SSF52540 275 349 3.49E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25575 2d51161647ef53999a29aa7284a506e5 1067 SMART SM00487 137 365 5.2E-13 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS26475 9207eb571da96a4e858c77263461bf7e 227 Pfam PF05593 RHS Repeat 192 226 5.5E-8 T 06-07-2017 IPR031325 RHS repeat LK06_RS26475 9207eb571da96a4e858c77263461bf7e 227 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 192 220 5.9E-8 T 06-07-2017 IPR006530 YD repeat LK06_RS26475 9207eb571da96a4e858c77263461bf7e 227 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 60 98 5.5E-4 T 06-07-2017 IPR006530 YD repeat LK06_RS07110 dc0e745730f0bcd6ab72a246fac35c76 138 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 43 115 1.0E-33 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 LK06_RS07110 dc0e745730f0bcd6ab72a246fac35c76 138 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 66 120 1.0E-22 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 LK06_RS07110 dc0e745730f0bcd6ab72a246fac35c76 138 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 17 120 31.802 T 06-07-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 LK06_RS07110 dc0e745730f0bcd6ab72a246fac35c76 138 SUPERFAMILY SSF141734 19 123 7.85E-47 T 06-07-2017 LK06_RS24570 ad582447720092a2cbafcb2dbcf28c4f 454 Gene3D G3DSA:3.40.640.10 66 340 2.7E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS24570 ad582447720092a2cbafcb2dbcf28c4f 454 SUPERFAMILY SSF53383 10 449 1.57E-126 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS24570 ad582447720092a2cbafcb2dbcf28c4f 454 Pfam PF00202 Aminotransferase class-III 30 446 7.2E-103 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS24570 ad582447720092a2cbafcb2dbcf28c4f 454 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 289 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS24570 ad582447720092a2cbafcb2dbcf28c4f 454 PIRSF PIRSF000521 29 449 1.0E-21 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS24570 ad582447720092a2cbafcb2dbcf28c4f 454 Gene3D G3DSA:3.90.1150.10 341 449 1.2E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS24570 ad582447720092a2cbafcb2dbcf28c4f 454 Gene3D G3DSA:3.90.1150.10 4 64 1.2E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS29930 d98537b7e5d0b975fd3de1d3925cd22b 356 Gene3D G3DSA:3.90.1150.10 266 352 4.7E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS29930 d98537b7e5d0b975fd3de1d3925cd22b 356 Gene3D G3DSA:3.40.640.10 10 262 1.8E-62 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS29930 d98537b7e5d0b975fd3de1d3925cd22b 356 Pfam PF01212 Beta-eliminating lyase 19 304 1.2E-56 T 06-07-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 LK06_RS29930 d98537b7e5d0b975fd3de1d3925cd22b 356 SUPERFAMILY SSF53383 17 353 2.61E-95 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 Gene3D G3DSA:1.10.1040.10 644 721 4.8E-8 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 SUPERFAMILY SSF51735 319 501 1.93E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 Gene3D G3DSA:3.40.50.720 310 504 9.6E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 323 500 4.3E-65 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 SUPERFAMILY SSF48179 631 721 5.19E-16 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 503 603 6.1E-17 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 Gene3D G3DSA:1.10.1040.10 505 603 3.9E-11 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 SUPERFAMILY SSF48179 502 644 3.06E-15 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 SUPERFAMILY SSF52096 2 308 1.19E-60 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 Gene3D G3DSA:3.90.226.10 3 206 2.2E-53 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 Gene3D G3DSA:3.90.226.10 240 299 2.2E-53 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS28625 03de54afb678e23e5afe91f70c209dd6 725 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 206 1.1E-29 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS03995 0fe2fce7c7c8f529a2f60c417a4a4583 145 Gene3D G3DSA:3.30.450.30 21 140 1.9E-24 T 06-07-2017 LK06_RS03995 0fe2fce7c7c8f529a2f60c417a4a4583 145 SUPERFAMILY SSF103196 20 142 1.31E-30 T 06-07-2017 LK06_RS03995 0fe2fce7c7c8f529a2f60c417a4a4583 145 SMART SM00960 23 113 2.8E-27 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS03995 0fe2fce7c7c8f529a2f60c417a4a4583 145 Pfam PF03259 Roadblock/LC7 domain 23 112 1.1E-21 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS00565 631ce4df1bf0f5cc2ff73fe9a8d8a1b0 249 Gene3D G3DSA:3.20.20.370 57 244 2.2E-49 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS00565 631ce4df1bf0f5cc2ff73fe9a8d8a1b0 249 SUPERFAMILY SSF88713 58 244 6.92E-50 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS00565 631ce4df1bf0f5cc2ff73fe9a8d8a1b0 249 Pfam PF01522 Polysaccharide deacetylase 59 181 1.3E-25 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS28245 6ed1a589d995955d1eb3ff617563f13f 225 SMART SM00345 24 82 7.4E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS28245 6ed1a589d995955d1eb3ff617563f13f 225 Gene3D G3DSA:1.10.10.10 11 83 1.4E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28245 6ed1a589d995955d1eb3ff617563f13f 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 3.4E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS28245 6ed1a589d995955d1eb3ff617563f13f 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 3.4E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS28245 6ed1a589d995955d1eb3ff617563f13f 225 Pfam PF07729 FCD domain 92 213 3.7E-23 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS28245 6ed1a589d995955d1eb3ff617563f13f 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 82 2.8E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS28245 6ed1a589d995955d1eb3ff617563f13f 225 SUPERFAMILY SSF46785 14 108 4.43E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28245 6ed1a589d995955d1eb3ff617563f13f 225 SUPERFAMILY SSF48008 89 217 2.88E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS28245 6ed1a589d995955d1eb3ff617563f13f 225 SMART SM00895 92 214 3.4E-16 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS28245 6ed1a589d995955d1eb3ff617563f13f 225 Gene3D G3DSA:1.20.120.530 85 217 4.2E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS25805 d482f42c2c683b160236515526f66168 401 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 308 7.4E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25805 d482f42c2c683b160236515526f66168 401 Gene3D G3DSA:3.50.50.60 7 127 2.2E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25805 d482f42c2c683b160236515526f66168 401 Gene3D G3DSA:3.50.50.60 176 332 1.5E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25805 d482f42c2c683b160236515526f66168 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 4.1E-7 T 06-07-2017 LK06_RS25805 d482f42c2c683b160236515526f66168 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 4.1E-7 T 06-07-2017 LK06_RS25805 d482f42c2c683b160236515526f66168 401 SUPERFAMILY SSF51905 119 259 1.13E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25805 d482f42c2c683b160236515526f66168 401 SUPERFAMILY SSF51905 8 89 8.05E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25805 d482f42c2c683b160236515526f66168 401 SUPERFAMILY SSF51905 179 395 8.05E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS22410 b97a3d20bef96f8b84a38f42bd0b366f 361 Gene3D G3DSA:1.10.600.10 21 337 6.5E-85 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS22410 b97a3d20bef96f8b84a38f42bd0b366f 361 SUPERFAMILY SSF48576 30 337 1.9E-50 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS08815 80b0ff94579e9b4cc76f15c61619b92b 405 SUPERFAMILY SSF53474 141 161 1.46E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08815 80b0ff94579e9b4cc76f15c61619b92b 405 SUPERFAMILY SSF53474 246 330 1.46E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08815 80b0ff94579e9b4cc76f15c61619b92b 405 Gene3D G3DSA:3.40.50.1820 240 329 1.5E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08815 80b0ff94579e9b4cc76f15c61619b92b 405 Gene3D G3DSA:3.40.50.1820 145 169 1.5E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08815 80b0ff94579e9b4cc76f15c61619b92b 405 Pfam PF06259 Alpha/beta hydrolase 157 330 9.1E-56 T 06-07-2017 IPR010427 Protein of unknown function DUF1023 LK06_RS06470 0e9f41140db5ca6392687d8af8ddc8d7 105 Gene3D G3DSA:2.102.10.10 1 103 2.2E-34 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS06470 0e9f41140db5ca6392687d8af8ddc8d7 105 SUPERFAMILY SSF50022 2 102 1.1E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS06470 0e9f41140db5ca6392687d8af8ddc8d7 105 Pfam PF00355 Rieske [2Fe-2S] domain 4 89 3.2E-21 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS27745 4278027bb3954218ca81be19235b01dc 236 Pfam PF02441 Flavoprotein 40 163 1.8E-12 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS27745 4278027bb3954218ca81be19235b01dc 236 SUPERFAMILY SSF52507 39 214 4.58E-23 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS27745 4278027bb3954218ca81be19235b01dc 236 Gene3D G3DSA:3.40.50.1950 37 201 6.7E-22 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS27340 220efff2e860a4bab4dece022865b274 557 Gene3D G3DSA:3.40.50.980 51 205 1.1E-26 T 06-07-2017 LK06_RS27340 220efff2e860a4bab4dece022865b274 557 SUPERFAMILY SSF56801 15 545 1.31E-130 T 06-07-2017 LK06_RS27340 220efff2e860a4bab4dece022865b274 557 Gene3D G3DSA:2.30.38.10 365 441 1.3E-18 T 06-07-2017 LK06_RS27340 220efff2e860a4bab4dece022865b274 557 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 533 1.5E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS27340 220efff2e860a4bab4dece022865b274 557 Pfam PF00501 AMP-binding enzyme 50 447 1.3E-75 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS27340 220efff2e860a4bab4dece022865b274 557 Gene3D G3DSA:3.30.300.30 446 549 7.9E-23 T 06-07-2017 LK06_RS27340 220efff2e860a4bab4dece022865b274 557 Gene3D G3DSA:3.40.50.980 206 364 2.7E-26 T 06-07-2017 LK06_RS18925 872ca7329cda1ffea6143aa894330582 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 58 8.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS18925 872ca7329cda1ffea6143aa894330582 211 Gene3D G3DSA:1.10.357.10 8 181 8.5E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS18925 872ca7329cda1ffea6143aa894330582 211 SUPERFAMILY SSF48498 88 195 8.9E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS18925 872ca7329cda1ffea6143aa894330582 211 SUPERFAMILY SSF46689 11 72 1.61E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 SUPERFAMILY SSF48452 326 355 2.69E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 SUPERFAMILY SSF48452 382 468 2.69E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 SUPERFAMILY SSF48452 86 346 6.83E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 Pfam PF13432 Tetratricopeptide repeat 260 322 4.6E-9 T 06-07-2017 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 Gene3D G3DSA:1.25.40.10 365 466 2.7E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 Gene3D G3DSA:1.25.40.10 90 350 6.9E-30 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 SMART SM00028 430 463 29.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 SMART SM00028 101 141 230.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 SMART SM00028 146 179 16.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 SMART SM00028 288 321 0.36 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS11295 e0e8c34249f611e4112db8a7174a6656 492 SMART SM00028 254 287 0.053 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS17545 9e18c057efabb92f18a101a66e6be4d2 371 Pfam PF05235 CHAD domain 47 323 8.8E-24 T 06-07-2017 IPR007899 CHAD domain LK06_RS17545 9e18c057efabb92f18a101a66e6be4d2 371 SMART SM00880 21 357 5.3E-7 T 06-07-2017 IPR007899 CHAD domain LK06_RS09775 6eae521354ba3114534c8ccf41ed4a16 422 SUPERFAMILY SSF56349 74 398 2.69E-70 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS09775 6eae521354ba3114534c8ccf41ed4a16 422 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 74 131 1.1E-7 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS09775 6eae521354ba3114534c8ccf41ed4a16 422 Pfam PF00589 Phage integrase family 206 389 6.3E-29 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS09775 6eae521354ba3114534c8ccf41ed4a16 422 Gene3D G3DSA:1.10.443.10 204 398 2.3E-46 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS09775 6eae521354ba3114534c8ccf41ed4a16 422 Gene3D G3DSA:1.10.150.130 74 200 3.5E-18 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS02955 608043ab6a8dc7b87eaf9eeed6ddc744 1002 Pfam PF13558 Putative exonuclease SbcCD, C subunit 889 954 2.4E-13 T 06-07-2017 LK06_RS02955 608043ab6a8dc7b87eaf9eeed6ddc744 1002 SUPERFAMILY SSF52540 773 985 3.21E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02955 608043ab6a8dc7b87eaf9eeed6ddc744 1002 SUPERFAMILY SSF52540 287 323 3.21E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02955 608043ab6a8dc7b87eaf9eeed6ddc744 1002 SUPERFAMILY SSF52540 2 189 3.21E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02955 608043ab6a8dc7b87eaf9eeed6ddc744 1002 Pfam PF13476 AAA domain 5 304 8.0E-26 T 06-07-2017 LK06_RS02955 608043ab6a8dc7b87eaf9eeed6ddc744 1002 Gene3D G3DSA:3.40.50.300 854 991 6.9E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02955 608043ab6a8dc7b87eaf9eeed6ddc744 1002 Gene3D G3DSA:3.40.50.300 444 445 6.9E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02955 608043ab6a8dc7b87eaf9eeed6ddc744 1002 Gene3D G3DSA:3.40.50.300 2 182 6.9E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26095 4e0fd52dcf71f2ab9ab6a71aa591a9be 530 Gene3D G3DSA:3.30.300.30 428 526 1.5E-34 T 06-07-2017 LK06_RS26095 4e0fd52dcf71f2ab9ab6a71aa591a9be 530 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS26095 4e0fd52dcf71f2ab9ab6a71aa591a9be 530 Gene3D G3DSA:2.30.38.10 356 427 8.2E-13 T 06-07-2017 LK06_RS26095 4e0fd52dcf71f2ab9ab6a71aa591a9be 530 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 517 1.4E-24 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS26095 4e0fd52dcf71f2ab9ab6a71aa591a9be 530 SUPERFAMILY SSF56801 58 525 3.4E-130 T 06-07-2017 LK06_RS26095 4e0fd52dcf71f2ab9ab6a71aa591a9be 530 Gene3D G3DSA:3.40.50.980 57 197 6.9E-29 T 06-07-2017 LK06_RS26095 4e0fd52dcf71f2ab9ab6a71aa591a9be 530 Gene3D G3DSA:3.40.50.980 198 348 4.9E-35 T 06-07-2017 LK06_RS26095 4e0fd52dcf71f2ab9ab6a71aa591a9be 530 Pfam PF00501 AMP-binding enzyme 57 433 2.1E-75 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS02100 23bc021bfca9a8f89af96cec1e367584 613 Gene3D G3DSA:3.40.50.300 23 135 4.2E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02100 23bc021bfca9a8f89af96cec1e367584 613 Pfam PF00196 Bacterial regulatory proteins, luxR family 551 601 4.3E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS02100 23bc021bfca9a8f89af96cec1e367584 613 SUPERFAMILY SSF46894 545 603 1.94E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS02100 23bc021bfca9a8f89af96cec1e367584 613 Gene3D G3DSA:1.10.10.10 549 601 7.9E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02100 23bc021bfca9a8f89af96cec1e367584 613 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 581 593 3.0E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS02100 23bc021bfca9a8f89af96cec1e367584 613 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 551 565 3.0E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS02100 23bc021bfca9a8f89af96cec1e367584 613 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 565 581 3.0E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS02100 23bc021bfca9a8f89af96cec1e367584 613 SUPERFAMILY SSF52540 17 207 9.38E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02100 23bc021bfca9a8f89af96cec1e367584 613 SMART SM00421 548 605 1.2E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 SUPERFAMILY SSF55785 212 312 6.28E-6 T 06-07-2017 IPR000014 PAS domain LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 Gene3D G3DSA:3.30.450.20 36 173 7.5E-45 T 06-07-2017 LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 Gene3D G3DSA:3.30.450.40 334 507 1.4E-37 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 SUPERFAMILY SSF81606 540 746 8.37E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 Pfam PF17203 Single cache domain 3 44 168 1.4E-27 T 06-07-2017 IPR033463 Single cache domain 3 LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 SMART SM00331 527 747 1.4E-38 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 SUPERFAMILY SSF55781 350 509 4.36E-15 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 Gene3D G3DSA:3.30.450.20 216 312 4.3E-6 T 06-07-2017 LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 Pfam PF01590 GAF domain 406 499 3.0E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 SUPERFAMILY SSF103190 46 170 4.32E-34 T 06-07-2017 IPR029151 Periplasmic sensor domain-like LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 Pfam PF13581 Histidine kinase-like ATPase domain 761 868 5.5E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 Pfam PF13188 PAS domain 217 256 2.1E-4 T 06-07-2017 IPR000014 PAS domain LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 SMART SM00091 215 280 0.0034 T 06-07-2017 IPR000014 PAS domain LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 SUPERFAMILY SSF55874 792 868 6.22E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 SMART SM00065 345 509 1.0E-5 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS00820 b3d10d89d5d11f67f97f396cf80b8912 874 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 555 747 1.2E-55 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS13105 9f639f1f6aa8950c2ddd6ae38de22e23 251 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 23 230 1.6E-48 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 LK06_RS08535 d637ace6200dedab9dc5466bff5334c6 377 Pfam PF07690 Major Facilitator Superfamily 3 330 1.2E-32 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS08535 d637ace6200dedab9dc5466bff5334c6 377 Gene3D G3DSA:1.20.1250.20 193 363 6.0E-6 T 06-07-2017 LK06_RS08535 d637ace6200dedab9dc5466bff5334c6 377 Gene3D G3DSA:1.20.1250.20 3 175 3.7E-25 T 06-07-2017 LK06_RS08535 d637ace6200dedab9dc5466bff5334c6 377 ProSitePatterns PS00216 Sugar transport proteins signature 1. 43 59 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LK06_RS08535 d637ace6200dedab9dc5466bff5334c6 377 SUPERFAMILY SSF103473 2 362 2.75E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 SUPERFAMILY SSF90123 598 910 4.19E-39 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 16 540 7.3E-218 T 06-07-2017 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 ProSitePatterns PS00211 ABC transporters family signature. 1066 1080 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 Pfam PF00664 ABC transporter transmembrane region 22 282 2.4E-28 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 Pfam PF00664 ABC transporter transmembrane region 649 864 8.7E-6 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 SMART SM00382 358 544 2.2E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 SMART SM00382 954 1140 1.4E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 597 1124 4.8E-195 T 06-07-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 Gene3D G3DSA:3.40.50.300 929 1153 5.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 Gene3D G3DSA:3.40.50.300 332 542 1.3E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 SUPERFAMILY SSF52540 327 541 6.19E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 SUPERFAMILY SSF52540 922 1162 1.1E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 SUPERFAMILY SSF90123 2 320 6.67E-55 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 Pfam PF00005 ABC transporter 350 498 6.4E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 Pfam PF00005 ABC transporter 947 1093 3.6E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 Gene3D G3DSA:1.20.1560.10 598 911 4.8E-29 T 06-07-2017 LK06_RS16145 672144bbcbfabd2c9d07c18af1e9ca3b 1174 Gene3D G3DSA:1.20.1560.10 6 320 1.2E-46 T 06-07-2017 LK06_RS25150 5235e0cb5918da6cce74c8482c53c38c 496 SUPERFAMILY SSF52540 275 460 4.6E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25150 5235e0cb5918da6cce74c8482c53c38c 496 Gene3D G3DSA:3.40.50.300 273 436 1.6E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25150 5235e0cb5918da6cce74c8482c53c38c 496 Pfam PF01926 50S ribosome-binding GTPase 276 394 1.7E-20 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS25150 5235e0cb5918da6cce74c8482c53c38c 496 Pfam PF13167 GTP-binding GTPase N-terminal 97 184 1.2E-31 T 06-07-2017 IPR025121 GTPase HflX, N-terminal LK06_RS25150 5235e0cb5918da6cce74c8482c53c38c 496 Hamap MF_00900 GTPase HflX [hflX]. 99 464 47.63 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 LK06_RS25150 5235e0cb5918da6cce74c8482c53c38c 496 PIRSF PIRSF006809 71 492 1.1E-157 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 LK06_RS25150 5235e0cb5918da6cce74c8482c53c38c 496 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 343 361 5.0E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS25150 5235e0cb5918da6cce74c8482c53c38c 496 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 276 296 5.0E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS25150 5235e0cb5918da6cce74c8482c53c38c 496 Pfam PF16360 GTP-binding GTPase Middle Region 186 268 2.8E-28 T 06-07-2017 IPR032305 GTP-binding protein, middle domain LK06_RS25150 5235e0cb5918da6cce74c8482c53c38c 496 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 80 434 1.3E-131 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 LK06_RS20315 9b73667813199fe33cfa656a3c6d2e4b 376 SUPERFAMILY SSF52540 72 356 3.79E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20315 9b73667813199fe33cfa656a3c6d2e4b 376 Pfam PF07728 AAA domain (dynein-related subfamily) 94 232 1.0E-35 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 LK06_RS20315 9b73667813199fe33cfa656a3c6d2e4b 376 Gene3D G3DSA:3.40.50.300 76 245 5.3E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13560 90a85807b2b54348df9ae48c7fe4b2f2 617 SUPERFAMILY SSF52016 427 613 5.96E-62 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel LK06_RS13560 90a85807b2b54348df9ae48c7fe4b2f2 617 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LK06_RS13560 90a85807b2b54348df9ae48c7fe4b2f2 617 SUPERFAMILY SSF143975 4 426 1.83E-130 T 06-07-2017 LK06_RS13560 90a85807b2b54348df9ae48c7fe4b2f2 617 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 612 44.755 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LK06_RS13560 90a85807b2b54348df9ae48c7fe4b2f2 617 Pfam PF00920 Dehydratase family 35 609 9.2E-215 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LK06_RS13560 90a85807b2b54348df9ae48c7fe4b2f2 617 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 515 526 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LK06_RS13560 90a85807b2b54348df9ae48c7fe4b2f2 617 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 612 4.6E-234 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LK06_RS23275 206100453ff113bc5b03f6e219302242 236 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 13 230 1.0E-41 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 LK06_RS23275 206100453ff113bc5b03f6e219302242 236 PRINTS PR00123 ATP synthase A subunit signature 215 230 1.3E-16 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 LK06_RS23275 206100453ff113bc5b03f6e219302242 236 PRINTS PR00123 ATP synthase A subunit signature 72 88 1.3E-16 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 LK06_RS23275 206100453ff113bc5b03f6e219302242 236 PRINTS PR00123 ATP synthase A subunit signature 157 179 1.3E-16 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 LK06_RS23275 206100453ff113bc5b03f6e219302242 236 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 235 12.864 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 LK06_RS23275 206100453ff113bc5b03f6e219302242 236 ProSitePatterns PS00449 ATP synthase a subunit signature. 160 169 - T 06-07-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 LK06_RS23275 206100453ff113bc5b03f6e219302242 236 SUPERFAMILY SSF81336 65 228 1.22E-33 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 LK06_RS23275 206100453ff113bc5b03f6e219302242 236 Gene3D G3DSA:1.20.120.220 65 235 4.1E-38 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 LK06_RS23275 206100453ff113bc5b03f6e219302242 236 Pfam PF00119 ATP synthase A chain 14 228 7.4E-48 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 LK06_RS00275 880fe85964b419a506d2c5fa67a39acd 152 SMART SM00116 74 121 0.25 T 06-07-2017 IPR000644 CBS domain LK06_RS00275 880fe85964b419a506d2c5fa67a39acd 152 SMART SM00116 10 57 1.0E-5 T 06-07-2017 IPR000644 CBS domain LK06_RS00275 880fe85964b419a506d2c5fa67a39acd 152 SUPERFAMILY SSF54631 2 117 2.53E-30 T 06-07-2017 LK06_RS00275 880fe85964b419a506d2c5fa67a39acd 152 Gene3D G3DSA:3.10.580.10 2 117 3.1E-30 T 06-07-2017 LK06_RS00275 880fe85964b419a506d2c5fa67a39acd 152 Pfam PF00571 CBS domain 67 117 1.5E-8 T 06-07-2017 IPR000644 CBS domain LK06_RS00275 880fe85964b419a506d2c5fa67a39acd 152 Pfam PF00571 CBS domain 3 53 8.3E-12 T 06-07-2017 IPR000644 CBS domain LK06_RS26105 5f7c4452e37bf29feee106715568899d 132 SUPERFAMILY SSF55298 6 132 1.16E-24 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS26105 5f7c4452e37bf29feee106715568899d 132 Gene3D G3DSA:3.30.1330.40 3 132 6.9E-28 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS26105 5f7c4452e37bf29feee106715568899d 132 Pfam PF01042 Endoribonuclease L-PSP 12 130 1.1E-15 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family LK06_RS21740 abe41ae26c5c5c4743b9faf9b146b458 146 Gene3D G3DSA:1.10.10.10 2 141 5.1E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21740 abe41ae26c5c5c4743b9faf9b146b458 146 SMART SM00347 24 124 1.0E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS21740 abe41ae26c5c5c4743b9faf9b146b458 146 Pfam PF12802 MarR family 30 82 4.2E-12 T 06-07-2017 LK06_RS21740 abe41ae26c5c5c4743b9faf9b146b458 146 SUPERFAMILY SSF46785 4 139 8.38E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17575 fdde3ff4743742dd6be46efe3c418fab 372 SUPERFAMILY SSF50494 297 368 2.66E-53 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS17575 fdde3ff4743742dd6be46efe3c418fab 372 SUPERFAMILY SSF50494 138 266 2.66E-53 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS17575 fdde3ff4743742dd6be46efe3c418fab 372 Gene3D G3DSA:2.40.10.10 159 234 3.5E-30 T 06-07-2017 LK06_RS17575 fdde3ff4743742dd6be46efe3c418fab 372 Pfam PF13365 Trypsin-like peptidase domain 163 328 4.3E-32 T 06-07-2017 LK06_RS17575 fdde3ff4743742dd6be46efe3c418fab 372 PRINTS PR00834 HtrA/DegQ protease family signature 193 213 2.6E-25 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS17575 fdde3ff4743742dd6be46efe3c418fab 372 PRINTS PR00834 HtrA/DegQ protease family signature 299 316 2.6E-25 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS17575 fdde3ff4743742dd6be46efe3c418fab 372 PRINTS PR00834 HtrA/DegQ protease family signature 321 338 2.6E-25 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS17575 fdde3ff4743742dd6be46efe3c418fab 372 PRINTS PR00834 HtrA/DegQ protease family signature 172 184 2.6E-25 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS17575 fdde3ff4743742dd6be46efe3c418fab 372 Gene3D G3DSA:2.40.10.10 235 368 3.5E-39 T 06-07-2017 LK06_RS05240 52806a30f39de71dc3f382ce04f95fb3 483 Pfam PF02447 GntP family permease 28 118 2.5E-22 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 LK06_RS05240 52806a30f39de71dc3f382ce04f95fb3 483 Pfam PF02447 GntP family permease 134 482 1.1E-112 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 LK06_RS05240 52806a30f39de71dc3f382ce04f95fb3 483 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 29 483 1.3E-126 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 LK06_RS30035 cb5c1da7149b476da3c60a7ea8cee1b0 216 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 16 212 3.2E-44 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like LK06_RS30035 cb5c1da7149b476da3c60a7ea8cee1b0 216 Gene3D G3DSA:2.60.120.590 12 212 1.7E-52 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like LK06_RS30035 cb5c1da7149b476da3c60a7ea8cee1b0 216 SUPERFAMILY SSF51197 14 213 1.79E-44 T 06-07-2017 LK06_RS07200 b4208947167f1528cc0bc5811f47c204 441 Gene3D G3DSA:3.90.1200.10 58 235 6.7E-9 T 06-07-2017 LK06_RS07200 b4208947167f1528cc0bc5811f47c204 441 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 30 431 1.6E-118 T 06-07-2017 IPR018721 Protein of unknown function DUF2252 LK06_RS07200 b4208947167f1528cc0bc5811f47c204 441 SUPERFAMILY SSF56112 69 149 4.59E-8 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS30705 5496d087bea555e56a908a9d842bdd8f 708 Gene3D G3DSA:1.20.1640.10 132 339 2.4E-27 T 06-07-2017 LK06_RS30705 5496d087bea555e56a908a9d842bdd8f 708 Gene3D G3DSA:1.20.1640.10 475 687 5.0E-26 T 06-07-2017 LK06_RS30705 5496d087bea555e56a908a9d842bdd8f 708 SUPERFAMILY SSF82866 469 685 9.29E-29 T 06-07-2017 LK06_RS30705 5496d087bea555e56a908a9d842bdd8f 708 SUPERFAMILY SSF82866 141 335 1.96E-28 T 06-07-2017 LK06_RS30705 5496d087bea555e56a908a9d842bdd8f 708 Pfam PF03176 MMPL family 397 691 1.9E-52 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS30705 5496d087bea555e56a908a9d842bdd8f 708 Pfam PF03176 MMPL family 46 365 1.5E-63 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 SMART SM00487 47 232 1.9E-31 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 Pfam PF00270 DEAD/DEAH box helicase 53 201 1.0E-18 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 Pfam PF13234 rRNA-processing arch domain 510 611 3.7E-5 T 06-07-2017 IPR025696 rRNA-processing arch domain LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 Pfam PF00271 Helicase conserved C-terminal domain 375 454 8.6E-5 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 SUPERFAMILY SSF52540 374 468 7.57E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 SUPERFAMILY SSF52540 61 202 7.57E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 SUPERFAMILY SSF52540 280 332 7.57E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 Pfam PF08148 DSHCT (NUC185) domain 774 944 1.9E-36 T 06-07-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 SMART SM00490 365 454 5.0E-13 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 Gene3D G3DSA:3.40.50.300 377 464 5.4E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 Gene3D G3DSA:3.40.50.300 303 335 5.4E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 SMART SM01142 771 949 3.1E-61 T 06-07-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal LK06_RS04950 ca4413387637aea15b19a33f95a51be0 950 Gene3D G3DSA:3.40.50.300 46 231 2.5E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19955 daff54a365ce8c27c1f6900e795df1cc 176 Pfam PF04417 Protein of unknown function (DUF501) 36 156 5.2E-37 T 06-07-2017 IPR007511 Protein of unknown function DUF501 LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 Pfam PF06071 Protein of unknown function (DUF933) 278 361 2.5E-38 T 06-07-2017 IPR013029 Domain of unknown function DUF933 LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 Gene3D G3DSA:1.10.150.300 132 201 2.5E-18 T 06-07-2017 IPR023192 TGS-like domain LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 Gene3D G3DSA:3.10.20.30 262 362 7.0E-45 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 SUPERFAMILY SSF52540 3 300 7.1E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 Pfam PF01926 50S ribosome-binding GTPase 5 128 1.1E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 362 5.4E-131 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.2E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.2E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.2E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.2E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 362 41.906 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 Gene3D G3DSA:3.40.50.300 202 261 1.7E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 Gene3D G3DSA:3.40.50.300 3 131 1.7E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 SUPERFAMILY SSF81271 278 362 1.83E-34 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 LK06_RS21525 99f92122eb1044c0cc767eb53d363a6b 362 PIRSF PIRSF006641 1 362 3.0E-141 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 LK06_RS16490 093f94848aeec6598759510d2b358132 185 Pfam PF04542 Sigma-70 region 2 29 94 2.4E-8 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16490 093f94848aeec6598759510d2b358132 185 SUPERFAMILY SSF88946 24 110 8.63E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16490 093f94848aeec6598759510d2b358132 185 Gene3D G3DSA:1.10.10.10 117 177 1.8E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16490 093f94848aeec6598759510d2b358132 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 177 3.8E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16490 093f94848aeec6598759510d2b358132 185 SUPERFAMILY SSF88659 115 177 1.27E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16490 093f94848aeec6598759510d2b358132 185 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 24 180 4.2E-63 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 LK06_RS16490 093f94848aeec6598759510d2b358132 185 Pfam PF08281 Sigma-70, region 4 123 175 1.5E-18 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16490 093f94848aeec6598759510d2b358132 185 Gene3D G3DSA:1.10.1740.10 23 95 9.0E-14 T 06-07-2017 LK06_RS32010 6c092551d533c11cc02e2bc9cc8f1bc2 300 Gene3D G3DSA:3.40.1190.20 4 299 1.4E-92 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS32010 6c092551d533c11cc02e2bc9cc8f1bc2 300 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 245 258 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 LK06_RS32010 6c092551d533c11cc02e2bc9cc8f1bc2 300 SUPERFAMILY SSF53613 1 296 4.99E-77 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS32010 6c092551d533c11cc02e2bc9cc8f1bc2 300 Hamap MF_01987 Ribokinase [rbsK]. 4 300 25.207 T 06-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 LK06_RS32010 6c092551d533c11cc02e2bc9cc8f1bc2 300 PRINTS PR00990 Ribokinase signature 173 188 9.6E-32 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS32010 6c092551d533c11cc02e2bc9cc8f1bc2 300 PRINTS PR00990 Ribokinase signature 216 227 9.6E-32 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS32010 6c092551d533c11cc02e2bc9cc8f1bc2 300 PRINTS PR00990 Ribokinase signature 8 29 9.6E-32 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS32010 6c092551d533c11cc02e2bc9cc8f1bc2 300 PRINTS PR00990 Ribokinase signature 106 119 9.6E-32 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS32010 6c092551d533c11cc02e2bc9cc8f1bc2 300 PRINTS PR00990 Ribokinase signature 35 54 9.6E-32 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 LK06_RS32010 6c092551d533c11cc02e2bc9cc8f1bc2 300 Pfam PF00294 pfkB family carbohydrate kinase 6 293 1.6E-61 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB LK06_RS11790 dfa0ae99554e8f12dfb4e0230a3550df 399 Pfam PF14258 Domain of unknown function (DUF4350) 57 127 2.0E-11 T 06-07-2017 IPR025646 Domain of unknown function DUF4350 LK06_RS08430 fd1634340859a408513ad2b0fd1c9f75 278 Gene3D G3DSA:3.40.1390.30 115 221 8.8E-33 T 06-07-2017 LK06_RS08430 fd1634340859a408513ad2b0fd1c9f75 278 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 4 266 1.4E-48 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 LK06_RS08430 fd1634340859a408513ad2b0fd1c9f75 278 SUPERFAMILY SSF102705 3 269 1.96E-82 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 LK06_RS08430 fd1634340859a408513ad2b0fd1c9f75 278 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 247 5.7E-71 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 LK06_RS08430 fd1634340859a408513ad2b0fd1c9f75 278 Gene3D G3DSA:3.40.1390.30 3 114 1.6E-42 T 06-07-2017 LK06_RS08885 209be58eabbcbc6b6dcd70a6c12ee28a 154 SUPERFAMILY SSF46785 15 153 2.56E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08885 209be58eabbcbc6b6dcd70a6c12ee28a 154 Gene3D G3DSA:1.10.10.10 13 153 8.4E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08885 209be58eabbcbc6b6dcd70a6c12ee28a 154 Pfam PF01047 MarR family 51 106 4.1E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS08885 209be58eabbcbc6b6dcd70a6c12ee28a 154 SMART SM00347 43 141 5.5E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS08885 209be58eabbcbc6b6dcd70a6c12ee28a 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 131 151 1.0E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS08885 209be58eabbcbc6b6dcd70a6c12ee28a 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 98 1.0E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS08885 209be58eabbcbc6b6dcd70a6c12ee28a 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 118 1.0E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS08885 209be58eabbcbc6b6dcd70a6c12ee28a 154 ProSitePatterns PS01117 MarR-type HTH domain signature. 81 115 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site LK06_RS12255 afa3bbb9270d0f8e2d14ec0e1abcc5b1 185 Pfam PF00281 Ribosomal protein L5 29 85 1.5E-28 T 06-07-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12255 afa3bbb9270d0f8e2d14ec0e1abcc5b1 185 Pfam PF00673 ribosomal L5P family C-terminus 89 182 3.4E-39 T 06-07-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12255 afa3bbb9270d0f8e2d14ec0e1abcc5b1 185 Gene3D G3DSA:3.30.1440.10 7 183 3.2E-76 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12255 afa3bbb9270d0f8e2d14ec0e1abcc5b1 185 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 6 184 43.489 T 06-07-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12255 afa3bbb9270d0f8e2d14ec0e1abcc5b1 185 PIRSF PIRSF002161 1 185 1.5E-63 T 06-07-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12255 afa3bbb9270d0f8e2d14ec0e1abcc5b1 185 ProSitePatterns PS00358 Ribosomal protein L5 signature. 62 78 - T 06-07-2017 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12255 afa3bbb9270d0f8e2d14ec0e1abcc5b1 185 SUPERFAMILY SSF55282 8 183 2.59E-75 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS19275 bf29382c8b0bb449fea215083378da65 255 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 22 236 5.5E-40 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 LK06_RS19275 bf29382c8b0bb449fea215083378da65 255 SUPERFAMILY SSF53213 1 255 2.49E-79 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 LK06_RS19275 bf29382c8b0bb449fea215083378da65 255 Gene3D G3DSA:3.40.830.10 1 254 1.8E-81 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 LK06_RS19275 bf29382c8b0bb449fea215083378da65 255 PIRSF PIRSF006157 1 255 1.5E-82 T 06-07-2017 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 LK06_RS21705 97a02c98e8c239306e8552ee1c9c7a9a 89 SUPERFAMILY SSF143120 7 57 2.62E-11 T 06-07-2017 LK06_RS21705 97a02c98e8c239306e8552ee1c9c7a9a 89 Gene3D G3DSA:3.40.1620.10 9 55 5.4E-16 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LK06_RS21705 97a02c98e8c239306e8552ee1c9c7a9a 89 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 54 3.2E-11 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LK06_RS21705 97a02c98e8c239306e8552ee1c9c7a9a 89 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 9 57 5.0E-13 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 SUPERFAMILY SSF55979 249 374 1.62E-29 T 06-07-2017 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 SUPERFAMILY SSF55979 126 249 5.02E-18 T 06-07-2017 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 SUPERFAMILY SSF55979 2 119 6.52E-24 T 06-07-2017 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 118 2.3E-38 T 06-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 Gene3D G3DSA:3.10.150.10 252 374 1.9E-38 T 06-07-2017 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 PIRSF PIRSF000804 1 375 1.2E-93 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 246 5.2E-31 T 06-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 Gene3D G3DSA:3.10.150.10 126 250 1.4E-28 T 06-07-2017 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 Gene3D G3DSA:3.10.150.10 2 120 1.3E-31 T 06-07-2017 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 1.9E-88 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 SMART SM00480 17 370 5.3E-143 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS15850 50fdee3f00c3361e2cb7192d4e74c50f 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 372 1.1E-36 T 06-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS25350 dd9b362aeddb26d60df19bdd643ecce5 418 Gene3D G3DSA:1.10.580.10 81 280 1.1E-38 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LK06_RS25350 dd9b362aeddb26d60df19bdd643ecce5 418 Pfam PF12728 Helix-turn-helix domain 15 47 2.1E-6 T 06-07-2017 LK06_RS25350 dd9b362aeddb26d60df19bdd643ecce5 418 Pfam PF00285 Citrate synthase, C-terminal domain 80 403 1.2E-62 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25350 dd9b362aeddb26d60df19bdd643ecce5 418 SUPERFAMILY SSF48256 47 417 1.96E-70 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25350 dd9b362aeddb26d60df19bdd643ecce5 418 PRINTS PR00143 Citrate synthase signature 224 239 1.0E-22 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25350 dd9b362aeddb26d60df19bdd643ecce5 418 PRINTS PR00143 Citrate synthase signature 299 319 1.0E-22 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25350 dd9b362aeddb26d60df19bdd643ecce5 418 PRINTS PR00143 Citrate synthase signature 353 369 1.0E-22 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25350 dd9b362aeddb26d60df19bdd643ecce5 418 PRINTS PR00143 Citrate synthase signature 246 274 1.0E-22 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25350 dd9b362aeddb26d60df19bdd643ecce5 418 PRINTS PR00143 Citrate synthase signature 373 387 1.0E-22 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25350 dd9b362aeddb26d60df19bdd643ecce5 418 Gene3D G3DSA:1.10.230.10 281 371 3.1E-14 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 LK06_RS16315 ef7315ea6a587c730576897b8b00f47b 227 Pfam PF13581 Histidine kinase-like ATPase domain 50 166 2.8E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16315 ef7315ea6a587c730576897b8b00f47b 227 Gene3D G3DSA:3.30.565.10 52 170 1.3E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16315 ef7315ea6a587c730576897b8b00f47b 227 SUPERFAMILY SSF55874 69 170 6.71E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS18835 e9060a32d8e57aa2629655cb33551287 449 Pfam PF07690 Major Facilitator Superfamily 45 302 2.0E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS18835 e9060a32d8e57aa2629655cb33551287 449 Gene3D G3DSA:1.20.1250.20 253 440 1.4E-18 T 06-07-2017 LK06_RS18835 e9060a32d8e57aa2629655cb33551287 449 Gene3D G3DSA:1.20.1250.20 31 223 4.1E-26 T 06-07-2017 LK06_RS18835 e9060a32d8e57aa2629655cb33551287 449 SUPERFAMILY SSF103473 21 438 7.85E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 Gene3D G3DSA:1.10.10.10 92 173 5.3E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 SUPERFAMILY SSF46894 83 173 4.82E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 SMART SM01043 180 324 1.9E-45 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 SMART SM00862 98 173 3.6E-5 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 PRINTS PR00364 Disease resistance protein signature 452 466 1.2E-6 T 06-07-2017 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 PRINTS PR00364 Disease resistance protein signature 536 550 1.2E-6 T 06-07-2017 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 PRINTS PR00364 Disease resistance protein signature 380 395 1.2E-6 T 06-07-2017 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 PRINTS PR00364 Disease resistance protein signature 699 708 1.2E-6 T 06-07-2017 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 Pfam PF13191 AAA ATPase domain 355 509 1.9E-10 T 06-07-2017 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 Gene3D G3DSA:3.40.50.300 355 390 7.1E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 Pfam PF00486 Transcriptional regulatory protein, C terminal 104 171 1.1E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 Pfam PF03704 Bacterial transcriptional activator domain 180 324 6.3E-38 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 Gene3D G3DSA:1.25.40.10 516 607 5.4E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 Gene3D G3DSA:1.25.40.10 184 300 5.4E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 SUPERFAMILY SSF48452 178 343 3.52E-34 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 Gene3D G3DSA:3.40.50.300 391 456 3.3E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21130 9e20e06cfa3baa40898aa4fb33f4226e 708 SUPERFAMILY SSF52540 352 595 4.23E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20940 0b638543aef9d9b89d558616e8b4b99d 445 Pfam PF07690 Major Facilitator Superfamily 8 381 7.1E-51 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS20940 0b638543aef9d9b89d558616e8b4b99d 445 Gene3D G3DSA:1.20.1250.20 251 443 1.2E-19 T 06-07-2017 LK06_RS20940 0b638543aef9d9b89d558616e8b4b99d 445 SUPERFAMILY SSF103473 236 443 7.85E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS20940 0b638543aef9d9b89d558616e8b4b99d 445 SUPERFAMILY SSF103473 3 192 7.85E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS20940 0b638543aef9d9b89d558616e8b4b99d 445 Gene3D G3DSA:1.20.1250.20 3 182 1.5E-29 T 06-07-2017 LK06_RS07265 9eb816f9ec3d86c19c973b4c0ffd0c5e 378 Pfam PF05103 DivIVA protein 3 64 6.8E-14 T 06-07-2017 IPR007793 DivIVA family LK06_RS07265 9eb816f9ec3d86c19c973b4c0ffd0c5e 378 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 38 1.3E-16 T 06-07-2017 IPR019933 DivIVA domain LK06_RS25975 ffe42c4f6ce35e0ce923d2c23d4c5ae8 194 Pfam PF04542 Sigma-70 region 2 41 100 2.8E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25975 ffe42c4f6ce35e0ce923d2c23d4c5ae8 194 SUPERFAMILY SSF88659 126 190 5.45E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25975 ffe42c4f6ce35e0ce923d2c23d4c5ae8 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 190 1.4E-20 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25975 ffe42c4f6ce35e0ce923d2c23d4c5ae8 194 SUPERFAMILY SSF88946 11 118 9.42E-18 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25975 ffe42c4f6ce35e0ce923d2c23d4c5ae8 194 Gene3D G3DSA:1.10.1740.10 16 126 4.7E-18 T 06-07-2017 LK06_RS25975 ffe42c4f6ce35e0ce923d2c23d4c5ae8 194 Pfam PF08281 Sigma-70, region 4 133 186 1.3E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS25975 ffe42c4f6ce35e0ce923d2c23d4c5ae8 194 Gene3D G3DSA:1.10.10.10 127 191 2.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12390 34671d8fb90e3df6f38de552b6aa11a2 539 Pfam PF13556 PucR C-terminal helix-turn-helix domain 467 524 2.2E-16 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS12390 34671d8fb90e3df6f38de552b6aa11a2 539 Gene3D G3DSA:3.40.50.720 43 95 2.6E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12390 34671d8fb90e3df6f38de552b6aa11a2 539 SUPERFAMILY SSF51735 45 153 2.59E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12390 34671d8fb90e3df6f38de552b6aa11a2 539 Gene3D G3DSA:1.10.10.60 479 502 3.7E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS06055 13ad8d82af9314a13c02a1c1e2bddc29 539 Pfam PF00474 Sodium:solute symporter family 47 462 2.2E-91 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS06055 13ad8d82af9314a13c02a1c1e2bddc29 539 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 47 461 1.8E-57 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS31225 b0b1e739b0fd588dbe3bc954bf3bb121 617 Pfam PF05547 Immune inhibitor A peptidase M6 78 192 6.2E-6 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 LK06_RS31225 b0b1e739b0fd588dbe3bc954bf3bb121 617 SUPERFAMILY SSF55486 407 611 9.82E-33 T 06-07-2017 LK06_RS31225 b0b1e739b0fd588dbe3bc954bf3bb121 617 Pfam PF01433 Peptidase family M1 350 521 5.3E-10 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS31225 b0b1e739b0fd588dbe3bc954bf3bb121 617 Gene3D G3DSA:1.10.390.10 495 610 8.4E-9 T 06-07-2017 LK06_RS02575 13d2465cc8562ba04a2c4b0c6ecb3376 99 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS02575 13d2465cc8562ba04a2c4b0c6ecb3376 99 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS02575 13d2465cc8562ba04a2c4b0c6ecb3376 99 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 3.3E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS02575 13d2465cc8562ba04a2c4b0c6ecb3376 99 SUPERFAMILY SSF46689 3 84 1.15E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02575 13d2465cc8562ba04a2c4b0c6ecb3376 99 Gene3D G3DSA:1.10.357.10 2 98 3.4E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS12815 f0c3406f618603494ad9fec58f96ec8a 342 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 51 316 9.8E-22 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LK06_RS12815 f0c3406f618603494ad9fec58f96ec8a 342 PIRSF PIRSF001439 1 326 1.3E-54 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LK06_RS12815 f0c3406f618603494ad9fec58f96ec8a 342 Gene3D G3DSA:3.30.1780.10 2 141 1.3E-34 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 LK06_RS12815 f0c3406f618603494ad9fec58f96ec8a 342 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 2 326 8.8E-104 T 06-07-2017 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB LK06_RS12815 f0c3406f618603494ad9fec58f96ec8a 342 SUPERFAMILY SSF51735 2 325 2.46E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12815 f0c3406f618603494ad9fec58f96ec8a 342 Gene3D G3DSA:3.40.50.720 142 295 1.2E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11210 9f33a26aff8724da394b3199d7912ef1 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 298 2.0E-111 T 06-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 LK06_RS11210 9f33a26aff8724da394b3199d7912ef1 316 SUPERFAMILY SSF53686 5 295 2.23E-88 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS11210 9f33a26aff8724da394b3199d7912ef1 316 Gene3D G3DSA:3.40.50.1100 42 143 8.1E-39 T 06-07-2017 LK06_RS11210 9f33a26aff8724da394b3199d7912ef1 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 4.4E-69 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS11210 9f33a26aff8724da394b3199d7912ef1 316 Gene3D G3DSA:3.40.50.1100 1 41 2.0E-67 T 06-07-2017 LK06_RS11210 9f33a26aff8724da394b3199d7912ef1 316 Gene3D G3DSA:3.40.50.1100 149 301 2.0E-67 T 06-07-2017 LK06_RS11210 9f33a26aff8724da394b3199d7912ef1 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 LK06_RS11620 d8d4c87339293ca6c7ce2d7315e31216 426 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 284 414 3.5E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS11620 d8d4c87339293ca6c7ce2d7315e31216 426 SUPERFAMILY SSF161098 279 414 6.47E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS11620 d8d4c87339293ca6c7ce2d7315e31216 426 SUPERFAMILY SSF161098 48 137 6.47E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS11620 d8d4c87339293ca6c7ce2d7315e31216 426 SUPERFAMILY SSF160964 3 46 1.18E-5 T 06-07-2017 LK06_RS11620 d8d4c87339293ca6c7ce2d7315e31216 426 Gene3D G3DSA:1.10.3720.10 282 417 1.8E-70 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS11620 d8d4c87339293ca6c7ce2d7315e31216 426 Gene3D G3DSA:1.10.3720.10 5 130 1.8E-70 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS19245 653b472d2354023fd5021f4e50610fda 304 Pfam PF03466 LysR substrate binding domain 95 279 1.1E-18 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS19245 653b472d2354023fd5021f4e50610fda 304 Gene3D G3DSA:3.40.190.10 98 174 7.8E-13 T 06-07-2017 LK06_RS19245 653b472d2354023fd5021f4e50610fda 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS19245 653b472d2354023fd5021f4e50610fda 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS19245 653b472d2354023fd5021f4e50610fda 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS19245 653b472d2354023fd5021f4e50610fda 304 Gene3D G3DSA:1.10.10.10 2 85 2.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19245 653b472d2354023fd5021f4e50610fda 304 Gene3D G3DSA:3.40.190.10 175 267 4.5E-18 T 06-07-2017 LK06_RS19245 653b472d2354023fd5021f4e50610fda 304 SUPERFAMILY SSF46785 2 83 2.03E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19245 653b472d2354023fd5021f4e50610fda 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.9E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS19245 653b472d2354023fd5021f4e50610fda 304 SUPERFAMILY SSF53850 93 279 1.01E-17 T 06-07-2017 LK06_RS29605 b42d634724f57e252ba67c72d4aae833 201 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 66 187 2.5E-22 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS29605 b42d634724f57e252ba67c72d4aae833 201 Gene3D G3DSA:3.40.80.10 56 198 7.0E-42 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS29605 b42d634724f57e252ba67c72d4aae833 201 SMART SM00644 56 186 4.6E-41 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS29605 b42d634724f57e252ba67c72d4aae833 201 SUPERFAMILY SSF55846 56 199 1.96E-40 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS20990 4fb798997a860d0c895a098fca0bdb5c 266 Pfam PF01061 ABC-2 type transporter 9 219 5.5E-28 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS20990 4fb798997a860d0c895a098fca0bdb5c 266 PIRSF PIRSF006648 1 266 2.8E-75 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS29705 8527aa53bb942036ba62f142f26b439e 298 Pfam PF02618 YceG-like family 48 267 5.8E-60 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like LK06_RS29705 8527aa53bb942036ba62f142f26b439e 298 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 97 269 3.1E-44 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like LK06_RS29705 8527aa53bb942036ba62f142f26b439e 298 Gene3D G3DSA:3.30.160.60 243 270 1.7E-4 T 06-07-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 LK06_RS21725 98125aac6339bc1a72a9fec19aa55fa0 228 Gene3D G3DSA:1.20.810.10 45 213 6.0E-25 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 LK06_RS21725 98125aac6339bc1a72a9fec19aa55fa0 228 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 98 209 1.6E-15 T 06-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 LK06_RS21725 98125aac6339bc1a72a9fec19aa55fa0 228 SUPERFAMILY SSF81342 43 214 1.57E-22 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 Pfam PF00072 Response regulator receiver domain 5 119 6.7E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 1.6E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 SUPERFAMILY SSF46894 154 221 1.77E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 SMART SM00448 3 118 4.1E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 Gene3D G3DSA:3.40.50.2300 1 124 2.2E-34 T 06-07-2017 LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 7.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 7.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 7.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 Gene3D G3DSA:1.10.10.10 125 222 2.0E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 SUPERFAMILY SSF52172 3 129 1.38E-31 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS07705 d896ff128ba91ce411ecd859918c2525 226 SMART SM00421 158 215 2.1E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS19290 c206d55f89f810d1684c0bc5bdb89173 294 SUPERFAMILY SSF46689 24 100 5.2E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS19290 c206d55f89f810d1684c0bc5bdb89173 294 Gene3D G3DSA:1.10.357.10 232 286 6.9E-15 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS19290 c206d55f89f810d1684c0bc5bdb89173 294 Gene3D G3DSA:1.10.357.10 80 163 6.9E-15 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS19290 c206d55f89f810d1684c0bc5bdb89173 294 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 57 80 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS19290 c206d55f89f810d1684c0bc5bdb89173 294 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS19290 c206d55f89f810d1684c0bc5bdb89173 294 Gene3D G3DSA:1.10.10.60 25 79 1.1E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS19290 c206d55f89f810d1684c0bc5bdb89173 294 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 77 5.6E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23355 c97c6bc13d541d3c5badec03ce302991 261 SMART SM00382 33 217 7.4E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS23355 c97c6bc13d541d3c5badec03ce302991 261 SUPERFAMILY SSF52540 14 229 3.92E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23355 c97c6bc13d541d3c5badec03ce302991 261 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS23355 c97c6bc13d541d3c5badec03ce302991 261 Pfam PF00005 ABC transporter 25 167 1.0E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS23355 c97c6bc13d541d3c5badec03ce302991 261 Gene3D G3DSA:3.40.50.300 4 234 5.4E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07840 dd8e893e0689092836e0502e939c8719 162 Gene3D G3DSA:3.40.630.30 5 161 2.5E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS07840 dd8e893e0689092836e0502e939c8719 162 Pfam PF00583 Acetyltransferase (GNAT) family 55 136 6.8E-19 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS07840 dd8e893e0689092836e0502e939c8719 162 SUPERFAMILY SSF55729 3 160 2.99E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS07545 d22e31bea4010714a848919aaae98cc6 265 Gene3D G3DSA:3.60.21.10 3 265 4.3E-21 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS07545 d22e31bea4010714a848919aaae98cc6 265 Pfam PF00149 Calcineurin-like phosphoesterase 12 236 7.4E-9 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 LK06_RS07545 d22e31bea4010714a848919aaae98cc6 265 SUPERFAMILY SSF56300 95 262 5.43E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS07545 d22e31bea4010714a848919aaae98cc6 265 SUPERFAMILY SSF56300 11 56 5.43E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS04495 fc74bc5849ba8c25dc8e46deae882019 174 Pfam PF01323 DSBA-like thioredoxin domain 14 161 2.2E-22 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 LK06_RS04495 fc74bc5849ba8c25dc8e46deae882019 174 Gene3D G3DSA:3.40.30.10 11 165 3.4E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS04495 fc74bc5849ba8c25dc8e46deae882019 174 SUPERFAMILY SSF52833 12 162 5.93E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS16460 8e57197420d6c81f1d76d155831ce606 300 SMART SM00942 236 298 1.7E-8 T 06-07-2017 IPR014820 Primase, C-terminal 1 LK06_RS16460 8e57197420d6c81f1d76d155831ce606 300 SMART SM00943 16 200 3.1E-38 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal LK06_RS16460 8e57197420d6c81f1d76d155831ce606 300 SUPERFAMILY SSF56747 13 212 4.84E-33 T 06-07-2017 LK06_RS16460 8e57197420d6c81f1d76d155831ce606 300 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 16 197 5.5E-42 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal LK06_RS16715 f7ca3e1cc3760144573579c895a1d6a8 218 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 90 181 8.5E-14 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain LK06_RS22060 fa18b5e0ce7f33fa8b1e4b0a5e69f3b2 433 Pfam PF00571 CBS domain 284 345 0.0023 T 06-07-2017 IPR000644 CBS domain LK06_RS22060 fa18b5e0ce7f33fa8b1e4b0a5e69f3b2 433 Pfam PF00571 CBS domain 353 406 0.0011 T 06-07-2017 IPR000644 CBS domain LK06_RS22060 fa18b5e0ce7f33fa8b1e4b0a5e69f3b2 433 SMART SM00924 180 283 2.3E-34 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain LK06_RS22060 fa18b5e0ce7f33fa8b1e4b0a5e69f3b2 433 Gene3D G3DSA:3.10.580.10 283 407 3.8E-18 T 06-07-2017 LK06_RS22060 fa18b5e0ce7f33fa8b1e4b0a5e69f3b2 433 SUPERFAMILY SSF158791 168 280 3.27E-31 T 06-07-2017 LK06_RS22060 fa18b5e0ce7f33fa8b1e4b0a5e69f3b2 433 SUPERFAMILY SSF54631 283 415 3.92E-22 T 06-07-2017 LK06_RS22060 fa18b5e0ce7f33fa8b1e4b0a5e69f3b2 433 SUPERFAMILY SSF50346 11 74 1.14E-6 T 06-07-2017 IPR011033 PRC-barrel-like LK06_RS22060 fa18b5e0ce7f33fa8b1e4b0a5e69f3b2 433 Gene3D G3DSA:1.25.60.10 166 278 3.9E-40 T 06-07-2017 LK06_RS22060 fa18b5e0ce7f33fa8b1e4b0a5e69f3b2 433 Pfam PF03448 MgtE intracellular N domain 180 280 2.7E-27 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain LK06_RS25830 265d8b3311b34baa441ee04474f5fa2f 463 Gene3D G3DSA:3.40.640.10 86 339 2.1E-46 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS25830 265d8b3311b34baa441ee04474f5fa2f 463 Gene3D G3DSA:3.90.1150.10 341 435 7.0E-20 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS25830 265d8b3311b34baa441ee04474f5fa2f 463 Gene3D G3DSA:3.90.1150.10 19 85 7.0E-20 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS25830 265d8b3311b34baa441ee04474f5fa2f 463 Pfam PF00202 Aminotransferase class-III 51 364 1.5E-38 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS25830 265d8b3311b34baa441ee04474f5fa2f 463 SUPERFAMILY SSF53383 18 434 6.57E-79 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS19700 9fe85dc63491807652dcd3c52c35e9db 298 Pfam PF01026 TatD related DNase 29 296 4.6E-68 T 06-07-2017 IPR001130 TatD family GO:0016788 LK06_RS19700 9fe85dc63491807652dcd3c52c35e9db 298 PIRSF PIRSF005902 5 298 3.1E-67 T 06-07-2017 IPR001130 TatD family GO:0016788 LK06_RS19700 9fe85dc63491807652dcd3c52c35e9db 298 SUPERFAMILY SSF51556 26 297 1.5E-71 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS19700 9fe85dc63491807652dcd3c52c35e9db 298 Gene3D G3DSA:3.20.20.140 19 297 9.2E-78 T 06-07-2017 LK06_RS09730 71e020716f5f407dfa6aa76bff669472 421 Pfam PF00589 Phage integrase family 212 395 3.1E-29 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS09730 71e020716f5f407dfa6aa76bff669472 421 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 78 135 3.3E-10 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS09730 71e020716f5f407dfa6aa76bff669472 421 SUPERFAMILY SSF56349 163 404 6.18E-65 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS09730 71e020716f5f407dfa6aa76bff669472 421 SUPERFAMILY SSF56349 78 136 6.18E-65 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS09730 71e020716f5f407dfa6aa76bff669472 421 Gene3D G3DSA:1.10.150.130 78 204 1.4E-17 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS09730 71e020716f5f407dfa6aa76bff669472 421 Gene3D G3DSA:1.10.443.10 211 404 9.8E-44 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS20650 961fe04ec759cc3f287e840b491a895e 226 SMART SM00448 2 112 7.6E-43 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS20650 961fe04ec759cc3f287e840b491a895e 226 Gene3D G3DSA:1.10.10.10 146 224 3.7E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20650 961fe04ec759cc3f287e840b491a895e 226 SUPERFAMILY SSF52172 1 121 1.41E-39 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS20650 961fe04ec759cc3f287e840b491a895e 226 SMART SM00862 147 223 1.4E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS20650 961fe04ec759cc3f287e840b491a895e 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 1.5E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS20650 961fe04ec759cc3f287e840b491a895e 226 Pfam PF00072 Response regulator receiver domain 4 112 1.5E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS20650 961fe04ec759cc3f287e840b491a895e 226 Gene3D G3DSA:3.40.50.2300 1 145 6.0E-39 T 06-07-2017 LK06_RS20650 961fe04ec759cc3f287e840b491a895e 226 SUPERFAMILY SSF46894 131 223 4.25E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS28035 795d18593289bfba6c01e992b1902ec0 239 SUPERFAMILY SSF53335 187 209 2.43E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28035 795d18593289bfba6c01e992b1902ec0 239 SUPERFAMILY SSF53335 8 156 2.43E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28035 795d18593289bfba6c01e992b1902ec0 239 Pfam PF13649 Methyltransferase domain 52 144 1.5E-10 T 06-07-2017 LK06_RS28035 795d18593289bfba6c01e992b1902ec0 239 Gene3D G3DSA:3.40.50.150 5 207 6.4E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS32105 0b2d881b8767463fce339f17ce80ac19 216 SUPERFAMILY SSF102198 3 215 4.71E-56 T 06-07-2017 LK06_RS32105 0b2d881b8767463fce339f17ce80ac19 216 Gene3D G3DSA:3.50.30.50 3 215 4.1E-62 T 06-07-2017 LK06_RS32105 0b2d881b8767463fce339f17ce80ac19 216 Pfam PF04199 Putative cyclase 5 153 3.3E-34 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 LK06_RS09975 db80e75130c2f818b4849645174f00c0 162 Gene3D G3DSA:3.40.1400.10 1 149 8.0E-56 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 LK06_RS09975 db80e75130c2f818b4849645174f00c0 162 Pfam PF02502 Ribose/Galactose Isomerase 3 142 5.2E-46 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 LK06_RS09975 db80e75130c2f818b4849645174f00c0 162 PIRSF PIRSF005384 1 149 1.6E-50 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 LK06_RS09975 db80e75130c2f818b4849645174f00c0 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 6.4E-53 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 LK06_RS09975 db80e75130c2f818b4849645174f00c0 162 SUPERFAMILY SSF89623 1 151 1.24E-52 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 LK06_RS09975 db80e75130c2f818b4849645174f00c0 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 1.1E-74 T 06-07-2017 IPR011860 Ribose 5-phosphate isomerase GO:0004751 LK06_RS00760 5540637cefe1d87613046bd076e88b07 56 Gene3D G3DSA:3.40.50.150 2 56 1.9E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS00760 5540637cefe1d87613046bd076e88b07 56 Pfam PF04672 S-adenosyl methyltransferase 2 55 3.7E-9 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS23510 5408e02c95177c6d8442f2616460fffc 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 2.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23510 5408e02c95177c6d8442f2616460fffc 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 2.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23510 5408e02c95177c6d8442f2616460fffc 209 Pfam PF16859 Bacterial transcriptional repressor C-terminal 78 194 7.9E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS23510 5408e02c95177c6d8442f2616460fffc 209 Gene3D G3DSA:1.10.357.10 61 202 3.4E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS23510 5408e02c95177c6d8442f2616460fffc 209 SUPERFAMILY SSF48498 82 201 4.82E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS23510 5408e02c95177c6d8442f2616460fffc 209 SUPERFAMILY SSF46689 13 76 5.49E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS23510 5408e02c95177c6d8442f2616460fffc 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 5.0E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23510 5408e02c95177c6d8442f2616460fffc 209 Gene3D G3DSA:1.10.10.60 12 59 4.7E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS16635 c3037b72c5cbf0cb431550017fb75e31 465 SUPERFAMILY SSF103473 250 460 7.06E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS16635 c3037b72c5cbf0cb431550017fb75e31 465 SUPERFAMILY SSF103473 9 202 7.06E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS16635 c3037b72c5cbf0cb431550017fb75e31 465 Gene3D G3DSA:1.20.1250.20 260 421 4.6E-15 T 06-07-2017 LK06_RS16635 c3037b72c5cbf0cb431550017fb75e31 465 Pfam PF07690 Major Facilitator Superfamily 20 412 1.0E-51 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS16635 c3037b72c5cbf0cb431550017fb75e31 465 Gene3D G3DSA:1.20.1250.20 10 201 2.1E-31 T 06-07-2017 LK06_RS16635 c3037b72c5cbf0cb431550017fb75e31 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 403 422 3.7E-12 T 06-07-2017 LK06_RS16635 c3037b72c5cbf0cb431550017fb75e31 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 79 101 3.7E-12 T 06-07-2017 LK06_RS16635 c3037b72c5cbf0cb431550017fb75e31 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 3.7E-12 T 06-07-2017 LK06_RS16635 c3037b72c5cbf0cb431550017fb75e31 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 19 43 3.7E-12 T 06-07-2017 LK06_RS07190 c8b06f3354c678ec2b9b7c89920fbb0f 406 Pfam PF01936 NYN domain 6 166 3.4E-12 T 06-07-2017 IPR021139 NYN domain, limkain-b1-type LK06_RS07190 c8b06f3354c678ec2b9b7c89920fbb0f 406 Gene3D G3DSA:3.40.50.1010 3 171 4.8E-17 T 06-07-2017 IPR029060 PIN domain-like LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 689 2.4E-261 T 06-07-2017 IPR023836 EccCa-like, Actinobacteria LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 SUPERFAMILY SSF52540 431 656 4.83E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 742 1314 8.2E-232 T 06-07-2017 IPR023837 EccCb-like, Actinobacteria LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 Gene3D G3DSA:3.40.50.300 440 659 9.9E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 Gene3D G3DSA:3.40.50.300 1103 1218 6.9E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 Gene3D G3DSA:3.40.50.300 819 1006 1.2E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 Pfam PF01580 FtsK/SpoIIIE family 1103 1189 1.9E-7 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 Pfam PF01580 FtsK/SpoIIIE family 438 557 6.8E-24 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 Pfam PF01580 FtsK/SpoIIIE family 805 1038 8.7E-46 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 SUPERFAMILY SSF52540 760 1027 3.75E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 SUPERFAMILY SSF52540 1074 1249 5.84E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 SMART SM00382 466 645 0.84 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 SMART SM00382 823 1001 0.29 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS24855 2d530d70292d3d02628a8f1ccb8be26c 1321 SMART SM00382 1111 1311 2.1 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 Gene3D G3DSA:3.40.1390.20 204 342 9.6E-27 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 Gene3D G3DSA:3.40.50.10750 501 659 2.1E-66 T 06-07-2017 LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 PIRSF PIRSF006107 1 691 2.8E-180 T 06-07-2017 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 382 683 2.0E-121 T 06-07-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 Pfam PF01515 Phosphate acetyl/butaryl transferase 366 683 1.6E-125 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 Gene3D G3DSA:3.40.50.300 3 203 2.2E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 SUPERFAMILY SSF52540 4 216 2.12E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 SUPERFAMILY SSF75138 204 324 1.14E-19 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 Pfam PF07085 DRTGG domain 209 319 3.5E-22 T 06-07-2017 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 SUPERFAMILY SSF53659 365 686 1.11E-93 T 06-07-2017 LK06_RS23550 f7cc17bc847026df3a0b85c5ceb4ddc4 691 Pfam PF13500 AAA domain 3 191 8.4E-18 T 06-07-2017 LK06_RS15520 30d526a2905da89eff999359ce03a3dd 109 Gene3D G3DSA:3.40.250.10 11 102 3.7E-26 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS15520 30d526a2905da89eff999359ce03a3dd 109 SMART SM00450 4 97 4.2E-15 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS15520 30d526a2905da89eff999359ce03a3dd 109 Pfam PF00581 Rhodanese-like domain 10 93 2.5E-12 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS15520 30d526a2905da89eff999359ce03a3dd 109 SUPERFAMILY SSF52821 7 102 4.71E-27 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS23430 6413e8971cb76efbc43e24e00d0436fb 146 SUPERFAMILY SSF54593 1 138 1.51E-34 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS23430 6413e8971cb76efbc43e24e00d0436fb 146 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 136 2.6E-45 T 06-07-2017 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|Reactome: R-HSA-71032 LK06_RS23430 6413e8971cb76efbc43e24e00d0436fb 146 Gene3D G3DSA:3.10.180.10 1 136 1.0E-38 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS23430 6413e8971cb76efbc43e24e00d0436fb 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 2.5E-22 T 06-07-2017 LK06_RS00260 831c5df97c8fa10ff682eedcf4212b5b 72 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 6.6E-26 T 06-07-2017 IPR015035 Domain of unknown function DUF1918 LK06_RS00260 831c5df97c8fa10ff682eedcf4212b5b 72 SUPERFAMILY SSF50118 1 64 1.24E-23 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor LK06_RS12285 b1d3535ee39f5a91101d118bcb018246 274 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 8.9E-93 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 LK06_RS12285 b1d3535ee39f5a91101d118bcb018246 274 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.757 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 LK06_RS12285 b1d3535ee39f5a91101d118bcb018246 274 Gene3D G3DSA:3.30.300.20 17 106 6.1E-31 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS12285 b1d3535ee39f5a91101d118bcb018246 274 SMART SM00322 59 124 2.5E-7 T 06-07-2017 IPR004087 K Homology domain GO:0003676 LK06_RS12285 b1d3535ee39f5a91101d118bcb018246 274 SUPERFAMILY SSF54814 2 105 5.23E-34 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 LK06_RS12285 b1d3535ee39f5a91101d118bcb018246 274 Gene3D G3DSA:3.30.1140.32 107 206 7.3E-43 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12285 b1d3535ee39f5a91101d118bcb018246 274 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 06-07-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12285 b1d3535ee39f5a91101d118bcb018246 274 SUPERFAMILY SSF54821 106 205 4.19E-38 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12285 b1d3535ee39f5a91101d118bcb018246 274 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 2.9E-37 T 06-07-2017 LK06_RS12285 b1d3535ee39f5a91101d118bcb018246 274 Pfam PF07650 KH domain 38 109 9.4E-19 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS14140 46dab5646d6eafa3e4a705d6a800b6b3 276 Gene3D G3DSA:3.60.15.10 23 234 1.5E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS14140 46dab5646d6eafa3e4a705d6a800b6b3 276 SUPERFAMILY SSF56281 28 275 5.15E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS14140 46dab5646d6eafa3e4a705d6a800b6b3 276 Pfam PF00753 Metallo-beta-lactamase superfamily 36 204 6.3E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS14140 46dab5646d6eafa3e4a705d6a800b6b3 276 SMART SM00849 39 204 1.2E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS11250 1a0701cf312043193543d39e7a9744c7 448 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 16 382 2.7E-125 T 06-07-2017 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 LK06_RS11250 1a0701cf312043193543d39e7a9744c7 448 Gene3D G3DSA:3.20.140.10 12 379 2.1E-88 T 06-07-2017 LK06_RS11250 1a0701cf312043193543d39e7a9744c7 448 SUPERFAMILY SSF54675 12 144 6.41E-43 T 06-07-2017 LK06_RS11250 1a0701cf312043193543d39e7a9744c7 448 SUPERFAMILY SSF51690 146 438 2.21E-77 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 LK06_RS11250 1a0701cf312043193543d39e7a9744c7 448 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 163 330 2.4E-4 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 LK06_RS11250 1a0701cf312043193543d39e7a9744c7 448 PIRSF PIRSF000484 8 442 4.8E-101 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 LK06_RS20920 5f083330c7d7d1fdebc9dfe07172da92 227 Gene3D G3DSA:3.40.50.300 3 224 2.1E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20920 5f083330c7d7d1fdebc9dfe07172da92 227 SMART SM00382 30 226 1.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS20920 5f083330c7d7d1fdebc9dfe07172da92 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS20920 5f083330c7d7d1fdebc9dfe07172da92 227 Pfam PF00005 ABC transporter 21 169 2.4E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS20920 5f083330c7d7d1fdebc9dfe07172da92 227 SUPERFAMILY SSF52540 1 224 3.19E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23615 d68212ac019f20f7eeedec9d2d58cdd2 743 Gene3D G3DSA:3.40.50.300 598 739 1.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23615 d68212ac019f20f7eeedec9d2d58cdd2 743 Pfam PF13245 Part of AAA domain 183 247 1.3E-15 T 06-07-2017 LK06_RS23615 d68212ac019f20f7eeedec9d2d58cdd2 743 SUPERFAMILY SSF52540 168 247 1.75E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23615 d68212ac019f20f7eeedec9d2d58cdd2 743 SUPERFAMILY SSF52540 515 734 1.75E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23615 d68212ac019f20f7eeedec9d2d58cdd2 743 SUPERFAMILY SSF52540 327 402 1.75E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23615 d68212ac019f20f7eeedec9d2d58cdd2 743 Gene3D G3DSA:3.40.50.300 169 277 1.1E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23615 d68212ac019f20f7eeedec9d2d58cdd2 743 Gene3D G3DSA:3.40.50.300 504 597 1.1E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21500 59b422a3b2a8b491236d0fcad96ca8e1 76 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 10 65 1.2E-19 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LK06_RS21500 59b422a3b2a8b491236d0fcad96ca8e1 76 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 6 49 7.0E-14 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LK06_RS21500 59b422a3b2a8b491236d0fcad96ca8e1 76 Gene3D G3DSA:1.10.287.1040 7 70 4.2E-22 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LK06_RS21500 59b422a3b2a8b491236d0fcad96ca8e1 76 SUPERFAMILY SSF116842 4 67 3.27E-16 T 06-07-2017 LK06_RS21500 59b422a3b2a8b491236d0fcad96ca8e1 76 PIRSF PIRSF006488 1 76 3.6E-24 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LK06_RS21500 59b422a3b2a8b491236d0fcad96ca8e1 76 Pfam PF02609 Exonuclease VII small subunit 11 60 2.7E-16 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LK06_RS21500 59b422a3b2a8b491236d0fcad96ca8e1 76 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 10 70 13.995 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LK06_RS26580 64fed68172c8857d81896a376f2f30d2 135 Gene3D G3DSA:3.40.50.1010 74 128 6.3E-4 T 06-07-2017 IPR029060 PIN domain-like LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 SUPERFAMILY SSF88946 34 135 1.57E-31 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 62 279 5.1E-33 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 PRINTS PR00046 Major sigma-70 factor signature 234 246 3.1E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 PRINTS PR00046 Major sigma-70 factor signature 266 277 3.1E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 PRINTS PR00046 Major sigma-70 factor signature 251 266 3.1E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 PRINTS PR00046 Major sigma-70 factor signature 89 102 3.1E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 59 280 1.2E-88 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 Pfam PF04539 Sigma-70 region 3 144 208 2.3E-15 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 Pfam PF04542 Sigma-70 region 2 65 134 2.9E-18 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 Gene3D G3DSA:1.10.601.10 49 134 9.0E-26 T 06-07-2017 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 Pfam PF04545 Sigma-70, region 4 231 278 1.0E-15 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 SUPERFAMILY SSF88659 216 280 9.35E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 89 102 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 Gene3D G3DSA:1.10.10.10 135 188 6.7E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 SUPERFAMILY SSF88659 138 211 9.53E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS16675 6f41e7ff697f94708be8a6b40363cae6 285 Gene3D G3DSA:1.10.10.10 221 279 2.7E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13270 e18cb84b61e8f759057d3371254a47d3 307 SUPERFAMILY SSF46785 1 83 6.51E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13270 e18cb84b61e8f759057d3371254a47d3 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 5.5E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13270 e18cb84b61e8f759057d3371254a47d3 307 Gene3D G3DSA:1.10.10.10 1 84 7.9E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13270 e18cb84b61e8f759057d3371254a47d3 307 SUPERFAMILY SSF53850 86 290 2.05E-38 T 06-07-2017 LK06_RS13270 e18cb84b61e8f759057d3371254a47d3 307 Gene3D G3DSA:3.40.190.10 90 177 3.8E-23 T 06-07-2017 LK06_RS13270 e18cb84b61e8f759057d3371254a47d3 307 Pfam PF03466 LysR substrate binding domain 87 290 7.1E-41 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS13270 e18cb84b61e8f759057d3371254a47d3 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13270 e18cb84b61e8f759057d3371254a47d3 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13270 e18cb84b61e8f759057d3371254a47d3 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13270 e18cb84b61e8f759057d3371254a47d3 307 Gene3D G3DSA:3.40.190.10 178 264 4.4E-23 T 06-07-2017 LK06_RS31925 c21ee068ed1dccdb451335b334ef5e5f 302 SUPERFAMILY SSF52540 2 217 2.24E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31925 c21ee068ed1dccdb451335b334ef5e5f 302 SMART SM00382 20 196 6.9E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS31925 c21ee068ed1dccdb451335b334ef5e5f 302 Gene3D G3DSA:3.40.50.300 3 208 3.2E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31925 c21ee068ed1dccdb451335b334ef5e5f 302 Pfam PF00005 ABC transporter 11 147 3.9E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS31925 c21ee068ed1dccdb451335b334ef5e5f 302 ProSitePatterns PS00211 ABC transporters family signature. 120 134 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS12890 f10666292424bedaaff84ce8efd08770 549 Pfam PF00361 Proton-conducting membrane transporter 179 485 5.2E-73 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12890 f10666292424bedaaff84ce8efd08770 549 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 153 537 1.6E-114 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 LK06_RS12890 f10666292424bedaaff84ce8efd08770 549 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 25 538 17.889 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 Gene3D G3DSA:3.50.30.20 17 154 2.1E-59 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 Pfam PF00117 Glutamine amidotransferase class-I 197 378 2.0E-37 T 06-07-2017 IPR017926 Glutamine amidotransferase LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00097 Anthranilate synthase component II signature 236 245 1.9E-5 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00097 Anthranilate synthase component II signature 264 275 1.9E-5 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00097 Anthranilate synthase component II signature 355 368 1.9E-5 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 Gene3D G3DSA:3.40.50.880 167 383 1.0E-60 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 16 384 45.734 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 194 208 5.9E-30 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 264 280 5.9E-30 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 306 317 5.9E-30 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 281 298 5.9E-30 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 233 247 5.9E-30 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 SMART SM01097 16 146 1.6E-87 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 18 145 3.0E-52 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 SUPERFAMILY SSF52317 166 383 7.34E-50 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00096 Glutamine amidotransferase superfamily signature 236 245 8.3E-11 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00096 Glutamine amidotransferase superfamily signature 355 368 8.3E-11 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 PRINTS PR00096 Glutamine amidotransferase superfamily signature 264 275 8.3E-11 T 06-07-2017 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 SUPERFAMILY SSF52021 17 152 1.02E-55 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS04115 d013444b55af1a1e48396178fc66080f 385 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 18 381 2.3E-136 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 Gene3D G3DSA:1.10.60.10 75 133 1.1E-29 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 Gene3D G3DSA:1.10.10.10 2 73 3.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 5.6E-29 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 SUPERFAMILY SSF50037 130 229 1.83E-23 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 SMART SM00529 26 125 4.7E-48 T 06-07-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 Gene3D G3DSA:2.30.30.90 134 229 2.7E-32 T 06-07-2017 LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 SUPERFAMILY SSF47979 65 137 1.44E-25 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 SUPERFAMILY SSF46785 3 62 1.03E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 Pfam PF04023 FeoA domain 157 228 5.5E-7 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 SMART SM00899 153 229 6.0E-8 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 LK06_RS18715 0e2f56481a728e02764acc4b5327f3d3 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 3.0E-19 T 06-07-2017 IPR022687 DTXR-type HTH domain GO:0003677 LK06_RS05325 26cebf873d7fdd8214c544b924fba95d 153 Gene3D G3DSA:3.10.129.10 13 149 1.6E-36 T 06-07-2017 IPR029069 HotDog domain LK06_RS05325 26cebf873d7fdd8214c544b924fba95d 153 Pfam PF01575 MaoC like domain 15 132 2.0E-26 T 06-07-2017 IPR002539 MaoC-like domain LK06_RS05325 26cebf873d7fdd8214c544b924fba95d 153 SUPERFAMILY SSF54637 11 150 6.4E-39 T 06-07-2017 IPR029069 HotDog domain LK06_RS18920 012a7836d8a4c1a6fb9ad6e9fe73fb94 150 SMART SM00344 1 110 1.4E-42 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS18920 012a7836d8a4c1a6fb9ad6e9fe73fb94 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 4.5E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS18920 012a7836d8a4c1a6fb9ad6e9fe73fb94 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 4.5E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS18920 012a7836d8a4c1a6fb9ad6e9fe73fb94 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 4.5E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS18920 012a7836d8a4c1a6fb9ad6e9fe73fb94 150 SUPERFAMILY SSF54909 66 149 7.24E-17 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS18920 012a7836d8a4c1a6fb9ad6e9fe73fb94 150 SUPERFAMILY SSF46785 1 60 2.86E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18920 012a7836d8a4c1a6fb9ad6e9fe73fb94 150 Gene3D G3DSA:3.30.70.920 54 149 5.7E-26 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS18920 012a7836d8a4c1a6fb9ad6e9fe73fb94 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 3.7E-18 T 06-07-2017 LK06_RS18920 012a7836d8a4c1a6fb9ad6e9fe73fb94 150 Gene3D G3DSA:1.10.10.10 2 53 3.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18920 012a7836d8a4c1a6fb9ad6e9fe73fb94 150 Pfam PF01037 Lrp/AsnC ligand binding domain 67 140 2.7E-18 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS16035 3835e13b2aa4997a6108efcc85609568 150 Pfam PF00583 Acetyltransferase (GNAT) family 58 139 1.1E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS16035 3835e13b2aa4997a6108efcc85609568 150 Gene3D G3DSA:3.40.630.30 3 149 2.6E-42 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS16035 3835e13b2aa4997a6108efcc85609568 150 SUPERFAMILY SSF55729 3 144 3.04E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS31020 27f78aafbd70ee7919b8ba7c865fedb7 317 Gene3D G3DSA:3.30.470.30 25 138 1.2E-24 T 06-07-2017 LK06_RS31020 27f78aafbd70ee7919b8ba7c865fedb7 317 SUPERFAMILY SSF50249 196 307 3.66E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS31020 27f78aafbd70ee7919b8ba7c865fedb7 317 Gene3D G3DSA:3.30.1490.70 1 24 1.9E-17 T 06-07-2017 LK06_RS31020 27f78aafbd70ee7919b8ba7c865fedb7 317 Gene3D G3DSA:3.30.1490.70 149 192 1.9E-17 T 06-07-2017 LK06_RS31020 27f78aafbd70ee7919b8ba7c865fedb7 317 SUPERFAMILY SSF56091 10 191 4.32E-39 T 06-07-2017 LK06_RS31020 27f78aafbd70ee7919b8ba7c865fedb7 317 Pfam PF01068 ATP dependent DNA ligase domain 15 191 5.8E-26 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 LK06_RS31020 27f78aafbd70ee7919b8ba7c865fedb7 317 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 12 307 2.2E-69 T 06-07-2017 IPR014146 DNA ligase D, ligase domain LK06_RS31020 27f78aafbd70ee7919b8ba7c865fedb7 317 Pfam PF04679 ATP dependent DNA ligase C terminal region 213 302 1.5E-18 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 LK06_RS31020 27f78aafbd70ee7919b8ba7c865fedb7 317 Gene3D G3DSA:2.40.50.140 195 307 2.1E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS22595 8fdf8d42be131f70e229c3726f3e7e4d 187 SUPERFAMILY SSF81923 78 179 4.45E-10 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS22595 8fdf8d42be131f70e229c3726f3e7e4d 187 SUPERFAMILY SSF81923 3 55 4.05E-8 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS22595 8fdf8d42be131f70e229c3726f3e7e4d 187 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 135 177 1.3E-7 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS22595 8fdf8d42be131f70e229c3726f3e7e4d 187 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 19 54 5.2E-4 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS22595 8fdf8d42be131f70e229c3726f3e7e4d 187 Gene3D G3DSA:1.10.1780.10 1 45 1.1E-41 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS22595 8fdf8d42be131f70e229c3726f3e7e4d 187 Gene3D G3DSA:1.10.1780.10 79 179 1.1E-41 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 SUPERFAMILY SSF55424 338 459 6.36E-29 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 2.6E-34 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 2.6E-34 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 2.6E-34 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.6E-34 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.6E-34 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 SUPERFAMILY SSF51905 7 366 7.26E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PIRSF PIRSF000350 1 446 2.0E-71 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 459 1.2E-137 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 Gene3D G3DSA:3.50.50.60 138 330 3.2E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 3.6E-23 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 2.3E-64 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 2.3E-64 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 2.3E-64 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 2.3E-64 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 2.3E-64 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 2.3E-64 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 2.3E-64 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 2.3E-64 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 2.3E-64 T 06-07-2017 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 Gene3D G3DSA:3.30.390.30 341 459 2.2E-27 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 Gene3D G3DSA:3.50.50.60 9 137 1.2E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07795 a84afd046545ecf09fe9e4a342cd35fa 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 321 2.2E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02230 30f7c781a7f2285fcf61fe82d0e26b8c 214 SUPERFAMILY SSF48498 87 200 1.03E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS02230 30f7c781a7f2285fcf61fe82d0e26b8c 214 SUPERFAMILY SSF46689 8 89 2.67E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS02230 30f7c781a7f2285fcf61fe82d0e26b8c 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 3.8E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS02230 30f7c781a7f2285fcf61fe82d0e26b8c 214 Gene3D G3DSA:1.10.357.10 2 202 1.9E-48 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS02230 30f7c781a7f2285fcf61fe82d0e26b8c 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS02230 30f7c781a7f2285fcf61fe82d0e26b8c 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS02230 30f7c781a7f2285fcf61fe82d0e26b8c 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 61 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS08505 d505e1a5e2f0cf098f90418ed1ff1e3a 460 SUPERFAMILY SSF53756 26 432 9.42E-79 T 06-07-2017 LK06_RS08505 d505e1a5e2f0cf098f90418ed1ff1e3a 460 Pfam PF13439 Glycosyltransferase Family 4 36 238 6.1E-26 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS08505 d505e1a5e2f0cf098f90418ed1ff1e3a 460 Gene3D G3DSA:3.40.50.2000 226 408 1.7E-25 T 06-07-2017 LK06_RS08505 d505e1a5e2f0cf098f90418ed1ff1e3a 460 Pfam PF00534 Glycosyl transferases group 1 252 408 4.3E-28 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS02765 5a309efe027422114079a2d27cd258c7 348 SUPERFAMILY SSF89000 294 340 1.14E-12 T 06-07-2017 LK06_RS02765 5a309efe027422114079a2d27cd258c7 348 Pfam PF00682 HMGL-like 14 268 6.4E-43 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 LK06_RS02765 5a309efe027422114079a2d27cd258c7 348 Gene3D G3DSA:1.10.8.60 281 340 6.2E-21 T 06-07-2017 LK06_RS02765 5a309efe027422114079a2d27cd258c7 348 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 278 339 2.0E-22 T 06-07-2017 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 LK06_RS02765 5a309efe027422114079a2d27cd258c7 348 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 348 134.04 T 06-07-2017 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 LK06_RS02765 5a309efe027422114079a2d27cd258c7 348 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 13 340 2.3E-110 T 06-07-2017 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 LK06_RS02765 5a309efe027422114079a2d27cd258c7 348 Gene3D G3DSA:3.20.20.70 11 271 7.1E-50 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS02765 5a309efe027422114079a2d27cd258c7 348 Pfam PF07836 DmpG-like communication domain 279 340 2.0E-23 T 06-07-2017 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 LK06_RS02765 5a309efe027422114079a2d27cd258c7 348 SUPERFAMILY SSF51569 10 292 1.19E-61 T 06-07-2017 LK06_RS25185 581fd2e08919d0bb28094f9c17d31e5c 250 SMART SM01006 83 131 6.2E-12 T 06-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain LK06_RS25185 581fd2e08919d0bb28094f9c17d31e5c 250 Pfam PF13523 Acetyltransferase (GNAT) domain 87 232 3.8E-50 T 06-07-2017 LK06_RS25185 581fd2e08919d0bb28094f9c17d31e5c 250 SUPERFAMILY SSF55729 80 244 6.57E-47 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS25185 581fd2e08919d0bb28094f9c17d31e5c 250 Gene3D G3DSA:3.40.630.30 80 244 1.8E-50 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS11715 21a3c86d11664b649cdf45010f107115 222 SUPERFAMILY SSF56784 8 214 1.92E-32 T 06-07-2017 IPR023214 HAD-like domain LK06_RS11715 21a3c86d11664b649cdf45010f107115 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 187 1.7E-13 T 06-07-2017 IPR023214 HAD-like domain LK06_RS11715 21a3c86d11664b649cdf45010f107115 222 Gene3D G3DSA:1.10.150.240 26 76 7.1E-5 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 LK06_RS11715 21a3c86d11664b649cdf45010f107115 222 Gene3D G3DSA:3.40.50.1000 77 215 1.8E-18 T 06-07-2017 IPR023214 HAD-like domain LK06_RS03175 d80ba7d867c9e0a619bca825ef5b771d 442 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 281 296 5.6E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS03175 d80ba7d867c9e0a619bca825ef5b771d 442 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 128 143 5.6E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS03175 d80ba7d867c9e0a619bca825ef5b771d 442 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 300 312 5.6E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS03175 d80ba7d867c9e0a619bca825ef5b771d 442 Gene3D G3DSA:1.10.390.10 295 429 1.6E-18 T 06-07-2017 LK06_RS03175 d80ba7d867c9e0a619bca825ef5b771d 442 SUPERFAMILY SSF55486 201 428 9.52E-49 T 06-07-2017 LK06_RS03175 d80ba7d867c9e0a619bca825ef5b771d 442 SUPERFAMILY SSF63737 3 192 3.66E-30 T 06-07-2017 LK06_RS03175 d80ba7d867c9e0a619bca825ef5b771d 442 Pfam PF01433 Peptidase family M1 11 342 4.1E-30 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LK06_RS26480 9a7c5f8960901969f6493d78ac12be8f 117 Pfam PF05593 RHS Repeat 64 99 2.8E-9 T 06-07-2017 IPR031325 RHS repeat LK06_RS26480 9a7c5f8960901969f6493d78ac12be8f 117 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 64 97 7.8E-7 T 06-07-2017 IPR006530 YD repeat LK06_RS26480 9a7c5f8960901969f6493d78ac12be8f 117 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 33 61 0.0027 T 06-07-2017 IPR006530 YD repeat LK06_RS26480 9a7c5f8960901969f6493d78ac12be8f 117 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 84 113 4.5E-7 T 06-07-2017 IPR006530 YD repeat LK06_RS26480 9a7c5f8960901969f6493d78ac12be8f 117 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 42 80 3.2E-6 T 06-07-2017 IPR006530 YD repeat LK06_RS08860 5a5ab16ccbde62cc0c92ee13b6c10824 82 Gene3D G3DSA:1.10.1200.10 3 81 4.3E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS08860 5a5ab16ccbde62cc0c92ee13b6c10824 82 Pfam PF00550 Phosphopantetheine attachment site 12 77 4.0E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS08860 5a5ab16ccbde62cc0c92ee13b6c10824 82 SUPERFAMILY SSF47336 2 81 5.37E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS08860 5a5ab16ccbde62cc0c92ee13b6c10824 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 80 2.0E-17 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS08860 5a5ab16ccbde62cc0c92ee13b6c10824 82 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 17.175 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 PRINTS PR01036 Tetracycline resistance protein TetB signature 128 148 2.8E-10 T 06-07-2017 LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 PRINTS PR01036 Tetracycline resistance protein TetB signature 424 443 2.8E-10 T 06-07-2017 LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 PRINTS PR01036 Tetracycline resistance protein TetB signature 37 61 2.8E-10 T 06-07-2017 LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 2.8E-10 T 06-07-2017 LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 Gene3D G3DSA:1.20.1250.20 494 521 3.7E-22 T 06-07-2017 LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 Gene3D G3DSA:1.20.1250.20 38 207 8.4E-28 T 06-07-2017 LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 Gene3D G3DSA:1.20.1250.20 277 445 3.7E-22 T 06-07-2017 LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 Gene3D G3DSA:2.60.40.10 550 600 5.9E-12 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 SUPERFAMILY SSF49478 552 612 4.32E-10 T 06-07-2017 LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 SUPERFAMILY SSF103473 493 517 2.49E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 SUPERFAMILY SSF103473 271 443 2.49E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 SUPERFAMILY SSF103473 25 218 2.49E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 Pfam PF13620 Carboxypeptidase regulatory-like domain 549 613 8.5E-11 T 06-07-2017 LK06_RS16650 cf5d002540ccc44aeec0f0d8eeb9d0ab 629 Pfam PF07690 Major Facilitator Superfamily 38 433 1.0E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS01580 609d7f5575fdf6ac821fa71499cbed5d 256 SUPERFAMILY SSF55729 18 226 3.55E-42 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS01580 609d7f5575fdf6ac821fa71499cbed5d 256 Pfam PF13444 Acetyltransferase (GNAT) domain 36 137 9.8E-32 T 06-07-2017 LK06_RS01580 609d7f5575fdf6ac821fa71499cbed5d 256 Gene3D G3DSA:3.40.630.30 21 186 8.5E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS12535 f83bfe2e044785704eb34a5101a4cc92 218 Gene3D G3DSA:3.40.50.720 1 205 7.9E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12535 f83bfe2e044785704eb34a5101a4cc92 218 Pfam PF13460 NAD(P)H-binding 7 190 9.8E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12535 f83bfe2e044785704eb34a5101a4cc92 218 SUPERFAMILY SSF51735 1 205 2.0E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26925 36c8f4f33662e7aab07d50bb6a1197c9 245 Gene3D G3DSA:3.40.50.1400 6 119 8.3E-24 T 06-07-2017 LK06_RS26925 36c8f4f33662e7aab07d50bb6a1197c9 245 Gene3D G3DSA:3.40.50.1400 126 235 1.1E-17 T 06-07-2017 LK06_RS26925 36c8f4f33662e7aab07d50bb6a1197c9 245 SUPERFAMILY SSF53800 6 235 1.2E-41 T 06-07-2017 LK06_RS26925 36c8f4f33662e7aab07d50bb6a1197c9 245 Pfam PF01903 CbiX 11 112 7.3E-22 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 LK06_RS26925 36c8f4f33662e7aab07d50bb6a1197c9 245 Pfam PF01903 CbiX 136 229 6.9E-13 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 SUPERFAMILY SSF53633 19 268 6.41E-61 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 ProSitePatterns PS00902 Glutamate 5-kinase signature. 222 239 - T 06-07-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 Gene3D G3DSA:2.30.130.10 286 378 1.5E-24 T 06-07-2017 IPR015947 PUA-like domain LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 Pfam PF00696 Amino acid kinase family 20 250 5.2E-42 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 PRINTS PR00474 Glutamate 5-kinase family signature 163 190 4.3E-53 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 PRINTS PR00474 Glutamate 5-kinase family signature 131 152 4.3E-53 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 PRINTS PR00474 Glutamate 5-kinase family signature 224 244 4.3E-53 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 PRINTS PR00474 Glutamate 5-kinase family signature 57 71 4.3E-53 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 PRINTS PR00474 Glutamate 5-kinase family signature 91 119 4.3E-53 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 Gene3D G3DSA:3.40.1160.10 19 268 8.1E-55 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 SMART SM00359 289 368 4.4E-17 T 06-07-2017 IPR002478 PUA domain GO:0003723 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 SUPERFAMILY SSF88697 289 379 5.36E-22 T 06-07-2017 IPR015947 PUA-like domain LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 TIGRFAM TIGR01027 proB: glutamate 5-kinase 19 378 1.0E-123 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 Hamap MF_00456 Glutamate 5-kinase [proB]. 19 270 34.948 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 PIRSF PIRSF000729 14 381 1.1E-119 T 06-07-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 LK06_RS09665 76c1d4be348561f5e869d206afdb1e22 382 Pfam PF01472 PUA domain 289 363 5.7E-19 T 06-07-2017 IPR002478 PUA domain GO:0003723 LK06_RS22490 6226f441ae122a09bbabce66c3ae731e 527 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 520 2.6E-99 T 06-07-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 LK06_RS22490 6226f441ae122a09bbabce66c3ae731e 527 Pfam PF00999 Sodium/hydrogen exchanger family 9 399 1.3E-56 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 LK06_RS31315 0d23558fc86b34b9e5d6dc04cc9ae3d1 363 SUPERFAMILY SSF56770 26 310 7.33E-64 T 06-07-2017 LK06_RS31315 0d23558fc86b34b9e5d6dc04cc9ae3d1 363 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 137 151 7.4E-7 T 06-07-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 LK06_RS31315 0d23558fc86b34b9e5d6dc04cc9ae3d1 363 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 255 281 7.4E-7 T 06-07-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 LK06_RS31315 0d23558fc86b34b9e5d6dc04cc9ae3d1 363 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 188 211 7.4E-7 T 06-07-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 LK06_RS31315 0d23558fc86b34b9e5d6dc04cc9ae3d1 363 Gene3D G3DSA:3.40.50.700 26 230 6.8E-43 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS31315 0d23558fc86b34b9e5d6dc04cc9ae3d1 363 Gene3D G3DSA:4.10.480.10 231 310 2.4E-25 T 06-07-2017 IPR027394 Cytochrome-c3 hydrogenase, C-terminal LK06_RS31315 0d23558fc86b34b9e5d6dc04cc9ae3d1 363 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 231 309 1.2E-22 T 06-07-2017 IPR027394 Cytochrome-c3 hydrogenase, C-terminal LK06_RS31315 0d23558fc86b34b9e5d6dc04cc9ae3d1 363 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 38 207 1.9E-26 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS31315 0d23558fc86b34b9e5d6dc04cc9ae3d1 363 PIRSF PIRSF000310 3 360 2.3E-82 T 06-07-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 LK06_RS25555 c64f2162dbc0eea63b4bf42596e60867 243 SMART SM00155 181 208 0.0036 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LK06_RS25555 c64f2162dbc0eea63b4bf42596e60867 243 Gene3D G3DSA:3.30.870.10 99 235 4.6E-20 T 06-07-2017 LK06_RS25555 c64f2162dbc0eea63b4bf42596e60867 243 Pfam PF13091 PLD-like domain 104 233 1.5E-14 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 LK06_RS25555 c64f2162dbc0eea63b4bf42596e60867 243 SUPERFAMILY SSF56024 97 233 5.16E-18 T 06-07-2017 LK06_RS11645 644e620b107295273a288655d7e0334a 137 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 135 1.2E-53 T 06-07-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 LK06_RS11645 644e620b107295273a288655d7e0334a 137 Pfam PF02566 OsmC-like protein 38 134 3.8E-20 T 06-07-2017 IPR003718 OsmC/Ohr family LK06_RS11645 644e620b107295273a288655d7e0334a 137 Gene3D G3DSA:3.30.300.20 45 136 1.2E-36 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS11645 644e620b107295273a288655d7e0334a 137 SUPERFAMILY SSF82784 1 135 1.31E-43 T 06-07-2017 IPR003718 OsmC/Ohr family LK06_RS11645 644e620b107295273a288655d7e0334a 137 Gene3D G3DSA:2.20.25.10 1 44 1.2E-19 T 06-07-2017 LK06_RS09350 5b0044ba33789e663d0853ab058e636b 362 Pfam PF02687 FtsX-like permease family 246 354 4.5E-12 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS28445 c78c400a11b470a2aecf51a349056c71 216 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 93 168 6.9E-11 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS28445 c78c400a11b470a2aecf51a349056c71 216 SUPERFAMILY SSF56214 92 212 9.55E-15 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS28445 c78c400a11b470a2aecf51a349056c71 216 PRINTS PR01399 Enterobactin synthetase component D signature 136 152 9.7E-26 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 LK06_RS28445 c78c400a11b470a2aecf51a349056c71 216 PRINTS PR01399 Enterobactin synthetase component D signature 59 77 9.7E-26 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 LK06_RS28445 c78c400a11b470a2aecf51a349056c71 216 PRINTS PR01399 Enterobactin synthetase component D signature 29 49 9.7E-26 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 LK06_RS28445 c78c400a11b470a2aecf51a349056c71 216 Gene3D G3DSA:3.90.470.20 111 164 1.2E-5 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS14165 70d2e6db33e5fe8c9faa4404da6cf176 467 SUPERFAMILY SSF52540 242 303 4.34E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14165 70d2e6db33e5fe8c9faa4404da6cf176 467 SUPERFAMILY SSF52540 29 200 4.34E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14165 70d2e6db33e5fe8c9faa4404da6cf176 467 Gene3D G3DSA:3.40.50.300 229 312 1.6E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14165 70d2e6db33e5fe8c9faa4404da6cf176 467 Gene3D G3DSA:3.40.50.300 27 188 1.6E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14165 70d2e6db33e5fe8c9faa4404da6cf176 467 Pfam PF02374 Anion-transporting ATPase 32 307 1.1E-27 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 LK06_RS07835 a181c297937e2067d3cf3925fec74a2d 394 Pfam PF13365 Trypsin-like peptidase domain 215 352 7.0E-20 T 06-07-2017 LK06_RS07835 a181c297937e2067d3cf3925fec74a2d 394 SUPERFAMILY SSF50494 209 372 4.33E-31 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS07835 a181c297937e2067d3cf3925fec74a2d 394 PRINTS PR00834 HtrA/DegQ protease family signature 283 307 2.5E-8 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS07835 a181c297937e2067d3cf3925fec74a2d 394 PRINTS PR00834 HtrA/DegQ protease family signature 323 340 2.5E-8 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS07835 a181c297937e2067d3cf3925fec74a2d 394 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 2.5E-8 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS07835 a181c297937e2067d3cf3925fec74a2d 394 PRINTS PR00834 HtrA/DegQ protease family signature 223 235 2.5E-8 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS07835 a181c297937e2067d3cf3925fec74a2d 394 Gene3D G3DSA:2.40.10.10 280 374 2.1E-12 T 06-07-2017 LK06_RS07835 a181c297937e2067d3cf3925fec74a2d 394 Gene3D G3DSA:2.40.10.10 192 269 3.5E-12 T 06-07-2017 LK06_RS07835 a181c297937e2067d3cf3925fec74a2d 394 Pfam PF02674 Colicin V production protein 4 146 7.8E-14 T 06-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 LK06_RS22690 58c444f6ad29cdde89f530bbbd3cc2e8 274 Gene3D G3DSA:3.20.20.80 69 272 4.3E-68 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS22690 58c444f6ad29cdde89f530bbbd3cc2e8 274 SMART SM00641 69 178 1.1E-50 T 06-07-2017 IPR018077 Glycoside hydrolase, family 25 subgroup LK06_RS22690 58c444f6ad29cdde89f530bbbd3cc2e8 274 Pfam PF01183 Glycosyl hydrolases family 25 72 256 1.8E-53 T 06-07-2017 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 LK06_RS22690 58c444f6ad29cdde89f530bbbd3cc2e8 274 SUPERFAMILY SSF51445 70 272 7.02E-61 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS06895 e401d2d47c0e4f6bb99850a23875c633 150 SUPERFAMILY SSF54637 25 149 9.24E-27 T 06-07-2017 IPR029069 HotDog domain LK06_RS06895 e401d2d47c0e4f6bb99850a23875c633 150 Gene3D G3DSA:3.10.129.10 23 148 2.9E-45 T 06-07-2017 IPR029069 HotDog domain LK06_RS06895 e401d2d47c0e4f6bb99850a23875c633 150 Pfam PF03061 Thioesterase superfamily 62 139 1.3E-17 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 LK06_RS06895 e401d2d47c0e4f6bb99850a23875c633 150 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 37 146 7.0E-29 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 LK06_RS14235 0f782cac610bd8ae17cf1d11f49cf26a 336 SUPERFAMILY SSF47413 132 176 3.0E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS14235 0f782cac610bd8ae17cf1d11f49cf26a 336 SMART SM00354 130 203 6.2E-8 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS14235 0f782cac610bd8ae17cf1d11f49cf26a 336 SUPERFAMILY SSF56349 194 206 7.4E-14 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS14235 0f782cac610bd8ae17cf1d11f49cf26a 336 SUPERFAMILY SSF56349 30 100 7.4E-14 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS14235 0f782cac610bd8ae17cf1d11f49cf26a 336 SUPERFAMILY SSF56349 233 297 7.4E-14 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS14235 0f782cac610bd8ae17cf1d11f49cf26a 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 133 175 1.5E-16 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS14235 0f782cac610bd8ae17cf1d11f49cf26a 336 Gene3D G3DSA:1.10.260.40 138 175 7.8E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS14235 0f782cac610bd8ae17cf1d11f49cf26a 336 Gene3D G3DSA:1.10.443.10 31 137 2.1E-26 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS14235 0f782cac610bd8ae17cf1d11f49cf26a 336 Gene3D G3DSA:1.10.443.10 243 298 2.1E-26 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS14235 0f782cac610bd8ae17cf1d11f49cf26a 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 133 151 - T 06-07-2017 LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 SMART SM00065 342 489 4.2E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 537 721 1.1E-43 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 Gene3D G3DSA:3.30.450.40 323 492 2.7E-16 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 SMART SM00091 201 267 0.0026 T 06-07-2017 IPR000014 PAS domain LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 SUPERFAMILY SSF55781 32 169 6.38E-6 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 Pfam PF13185 GAF domain 343 480 1.8E-15 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 Pfam PF08448 PAS fold 208 295 1.2E-5 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 Gene3D G3DSA:3.30.450.20 204 296 1.5E-9 T 06-07-2017 LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 SMART SM00331 507 722 8.9E-31 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 SUPERFAMILY SSF81606 524 720 4.45E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 SUPERFAMILY SSF55785 204 289 2.79E-8 T 06-07-2017 IPR000014 PAS domain LK06_RS00435 826e5719543180eb3534e447f3e3adbf 726 SUPERFAMILY SSF55781 344 492 2.4E-19 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00345 dc744bb44620879c202cc58b5cc1814b 220 SMART SM00116 76 124 3.2E-8 T 06-07-2017 IPR000644 CBS domain LK06_RS00345 dc744bb44620879c202cc58b5cc1814b 220 SMART SM00116 13 61 3.5E-8 T 06-07-2017 IPR000644 CBS domain LK06_RS00345 dc744bb44620879c202cc58b5cc1814b 220 Pfam PF00571 CBS domain 69 123 2.1E-13 T 06-07-2017 IPR000644 CBS domain LK06_RS00345 dc744bb44620879c202cc58b5cc1814b 220 Pfam PF00571 CBS domain 6 59 2.1E-13 T 06-07-2017 IPR000644 CBS domain LK06_RS00345 dc744bb44620879c202cc58b5cc1814b 220 Gene3D G3DSA:3.20.20.70 4 126 2.9E-31 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS00345 dc744bb44620879c202cc58b5cc1814b 220 Pfam PF04972 BON domain 127 190 1.5E-9 T 06-07-2017 IPR007055 BON domain LK06_RS00345 dc744bb44620879c202cc58b5cc1814b 220 SUPERFAMILY SSF54631 2 122 1.52E-33 T 06-07-2017 LK06_RS08175 6c4703bdbc0366dbb465b06c677f079c 102 SUPERFAMILY SSF56219 18 97 3.8E-11 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS08175 6c4703bdbc0366dbb465b06c677f079c 102 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 17 89 1.7E-7 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 Pfam PF00067 Cytochrome P450 196 391 2.0E-22 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 PRINTS PR00359 B-class P450 signature 313 340 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 PRINTS PR00359 B-class P450 signature 165 180 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 PRINTS PR00359 B-class P450 signature 362 371 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 PRINTS PR00359 B-class P450 signature 102 113 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 PRINTS PR00359 B-class P450 signature 371 382 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 PRINTS PR00359 B-class P450 signature 148 164 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 PRINTS PR00359 B-class P450 signature 295 306 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 PRINTS PR00359 B-class P450 signature 341 356 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 PRINTS PR00359 B-class P450 signature 209 231 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 Gene3D G3DSA:1.10.630.10 16 425 5.1E-132 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS19930 ae8e0c6f7a4d4099a4c58e4d0836702f 432 SUPERFAMILY SSF48264 15 424 1.44E-100 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS03480 d6c0ceed9ffad739600ca5c0fec8612f 877 Pfam PF00589 Phage integrase family 523 686 3.7E-13 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS03480 d6c0ceed9ffad739600ca5c0fec8612f 877 SUPERFAMILY SSF56349 442 691 1.38E-24 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS03480 d6c0ceed9ffad739600ca5c0fec8612f 877 Gene3D G3DSA:1.10.443.10 517 693 2.4E-23 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS07185 19b224de0945b842dd45ac6e213855a4 337 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS07185 19b224de0945b842dd45ac6e213855a4 337 SMART SM00382 51 235 2.2E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS07185 19b224de0945b842dd45ac6e213855a4 337 SUPERFAMILY SSF52540 10 250 1.88E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07185 19b224de0945b842dd45ac6e213855a4 337 Pfam PF00005 ABC transporter 43 185 2.3E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS07185 19b224de0945b842dd45ac6e213855a4 337 Gene3D G3DSA:3.40.50.300 10 252 2.8E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09055 01b8eefb337bb354d7d1c67104c01db7 409 Gene3D G3DSA:1.10.260.40 3 73 5.1E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS09055 01b8eefb337bb354d7d1c67104c01db7 409 SUPERFAMILY SSF47413 5 71 1.75E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS09055 01b8eefb337bb354d7d1c67104c01db7 409 Pfam PF13560 Helix-turn-helix domain 7 64 8.3E-8 T 06-07-2017 LK06_RS09055 01b8eefb337bb354d7d1c67104c01db7 409 Gene3D G3DSA:1.25.40.10 248 380 2.4E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS09055 01b8eefb337bb354d7d1c67104c01db7 409 SMART SM00530 11 67 8.5E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS18860 fe9bfcb3af3451b4882d93b9a19e39b7 392 SUPERFAMILY SSF51905 20 222 2.59E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS18860 fe9bfcb3af3451b4882d93b9a19e39b7 392 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 22 213 3.0E-30 T 06-07-2017 LK06_RS18860 fe9bfcb3af3451b4882d93b9a19e39b7 392 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 177 201 3.5E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS18860 fe9bfcb3af3451b4882d93b9a19e39b7 392 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 3.5E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS18860 fe9bfcb3af3451b4882d93b9a19e39b7 392 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 146 3.5E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS18860 fe9bfcb3af3451b4882d93b9a19e39b7 392 SUPERFAMILY SSF51905 180 391 5.33E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS18860 fe9bfcb3af3451b4882d93b9a19e39b7 392 Gene3D G3DSA:3.50.50.60 235 325 2.0E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS18860 fe9bfcb3af3451b4882d93b9a19e39b7 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 2.3E-8 T 06-07-2017 LK06_RS18860 fe9bfcb3af3451b4882d93b9a19e39b7 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 2.3E-8 T 06-07-2017 LK06_RS18860 fe9bfcb3af3451b4882d93b9a19e39b7 392 Gene3D G3DSA:3.50.50.60 13 217 2.3E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS31420 739cd81aa217881312dc8dc899964f34 239 Gene3D G3DSA:3.40.50.150 59 164 1.7E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS31420 739cd81aa217881312dc8dc899964f34 239 SUPERFAMILY SSF53335 59 183 1.12E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS31420 739cd81aa217881312dc8dc899964f34 239 Pfam PF13489 Methyltransferase domain 55 164 1.7E-10 T 06-07-2017 LK06_RS05015 cc1bcb97e4d660f88eb66c9e2bcaa79d 280 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 49 268 1.8E-119 T 06-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 LK06_RS05015 cc1bcb97e4d660f88eb66c9e2bcaa79d 280 PRINTS PR00141 Proteasome component signature 187 198 2.9E-6 T 06-07-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 LK06_RS05015 cc1bcb97e4d660f88eb66c9e2bcaa79d 280 PRINTS PR00141 Proteasome component signature 60 75 2.9E-6 T 06-07-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 LK06_RS05015 cc1bcb97e4d660f88eb66c9e2bcaa79d 280 PRINTS PR00141 Proteasome component signature 198 209 2.9E-6 T 06-07-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 LK06_RS05015 cc1bcb97e4d660f88eb66c9e2bcaa79d 280 Hamap MF_02113_B Proteasome subunit beta [prcB]. 7 274 50.225 T 06-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 LK06_RS05015 cc1bcb97e4d660f88eb66c9e2bcaa79d 280 Pfam PF00227 Proteasome subunit 51 230 6.4E-39 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 LK06_RS05015 cc1bcb97e4d660f88eb66c9e2bcaa79d 280 SUPERFAMILY SSF56235 31 262 5.5E-60 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS05015 cc1bcb97e4d660f88eb66c9e2bcaa79d 280 Gene3D G3DSA:3.60.20.10 53 259 7.6E-57 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS08235 8c9383d89a5b0c1db949f3d93f7407ef 278 Gene3D G3DSA:3.10.129.10 227 271 5.5E-4 T 06-07-2017 IPR029069 HotDog domain LK06_RS08235 8c9383d89a5b0c1db949f3d93f7407ef 278 PIRSF PIRSF006648 2 278 6.0E-79 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS08235 8c9383d89a5b0c1db949f3d93f7407ef 278 Pfam PF01061 ABC-2 type transporter 31 243 1.0E-32 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS30160 766d084cbb46fa3d67960d2d91774902 655 Pfam PF13556 PucR C-terminal helix-turn-helix domain 572 630 2.4E-17 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS30160 766d084cbb46fa3d67960d2d91774902 655 SUPERFAMILY SSF55781 73 256 2.4E-27 T 06-07-2017 IPR029016 GAF domain-like LK06_RS30160 766d084cbb46fa3d67960d2d91774902 655 Pfam PF13185 GAF domain 89 232 1.6E-15 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS30160 766d084cbb46fa3d67960d2d91774902 655 Gene3D G3DSA:3.30.450.40 67 244 4.1E-33 T 06-07-2017 IPR029016 GAF domain-like LK06_RS30160 766d084cbb46fa3d67960d2d91774902 655 SMART SM00065 90 241 6.0E-18 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 271 343 6.6E-14 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 Gene3D G3DSA:2.40.30.10 2 100 1.6E-23 T 06-07-2017 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 SUPERFAMILY SSF52343 98 245 1.44E-30 T 06-07-2017 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 SUPERFAMILY SSF63380 2 113 1.74E-22 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 301 309 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 Pfam PF00970 Oxidoreductase FAD-binding domain 8 109 1.6E-10 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 Gene3D G3DSA:3.40.50.80 101 241 5.3E-35 T 06-07-2017 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 Gene3D G3DSA:3.10.20.30 242 350 9.8E-31 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 119 138 3.3E-8 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 55 62 3.3E-8 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 104 113 3.3E-8 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 215 223 3.3E-8 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 4 353 4.4E-127 T 06-07-2017 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 SUPERFAMILY SSF54292 238 348 3.15E-27 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS15510 51871e92ec4a23b476bd2b874687752a 354 Pfam PF00175 Oxidoreductase NAD-binding domain 121 229 2.0E-10 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 35 539 4.5E-214 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 264 318 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 365 383 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 393 412 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 151 163 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 330 351 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 108 132 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 212 231 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 241 262 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 308 323 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 183 201 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 81 104 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 443 464 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 34 59 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 262 283 9.9E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 44 487 1.7E-144 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 Gene3D G3DSA:1.20.210.10 27 560 1.0E-194 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07650 612da250ff958fdebdfeef5bb8936dbe 577 SUPERFAMILY SSF81442 31 542 6.41E-175 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS13150 e29831092c5ba8a097106b6b96680e39 198 PRINTS PR01100 Shikimate kinase family signature 29 44 1.4E-6 T 06-07-2017 LK06_RS13150 e29831092c5ba8a097106b6b96680e39 198 PRINTS PR01100 Shikimate kinase family signature 127 144 1.4E-6 T 06-07-2017 LK06_RS13150 e29831092c5ba8a097106b6b96680e39 198 SUPERFAMILY SSF52540 26 188 1.05E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13150 e29831092c5ba8a097106b6b96680e39 198 Gene3D G3DSA:3.40.50.300 29 192 2.2E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13150 e29831092c5ba8a097106b6b96680e39 198 Pfam PF13671 AAA domain 29 172 2.5E-23 T 06-07-2017 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 ProSitePatterns PS01166 RNA polymerases beta chain signature. 868 880 - T 06-07-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Pfam PF10385 RNA polymerase beta subunit external 1 domain 502 568 5.3E-26 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Gene3D G3DSA:2.40.270.10 698 725 1.7E-75 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Gene3D G3DSA:2.40.270.10 865 1025 1.7E-75 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Gene3D G3DSA:3.90.1100.10 571 625 7.6E-146 T 06-07-2017 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Gene3D G3DSA:3.90.1100.10 29 169 7.6E-146 T 06-07-2017 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Gene3D G3DSA:3.90.1100.10 354 502 7.6E-146 T 06-07-2017 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Pfam PF04563 RNA polymerase beta subunit 37 409 2.0E-22 T 06-07-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Pfam PF00562 RNA polymerase Rpb2, domain 6 630 1047 8.1E-156 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Gene3D G3DSA:2.40.50.100 627 697 1.3E-26 T 06-07-2017 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Pfam PF04560 RNA polymerase Rpb2, domain 7 1049 1123 4.0E-27 T 06-07-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Gene3D G3DSA:2.40.50.150 734 864 1.8E-56 T 06-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Pfam PF04561 RNA polymerase Rpb2, domain 2 169 365 2.4E-31 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 23 1125 12.38 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Gene3D G3DSA:3.90.1110.10 171 341 2.5E-69 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 SUPERFAMILY SSF64484 22 1133 0.0 T 06-07-2017 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Gene3D G3DSA:2.30.150.10 503 568 2.1E-28 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 492 1.8E-28 T 06-07-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS12425 a176b7224db2a114b1816474d41a5a84 1161 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 236 842 0.0 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS02120 c28ebb61c63b71af34785122bcae93c0 100 SUPERFAMILY SSF54292 16 94 4.06E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS02120 c28ebb61c63b71af34785122bcae93c0 100 Gene3D G3DSA:3.10.20.30 8 85 3.9E-5 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS02120 c28ebb61c63b71af34785122bcae93c0 100 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 93 2.2E-27 T 06-07-2017 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 Gene3D G3DSA:3.40.50.261 341 499 5.2E-32 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 Gene3D G3DSA:3.40.630.30 22 186 2.9E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 SUPERFAMILY SSF52210 649 687 9.16E-16 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 SUPERFAMILY SSF52210 509 611 9.16E-16 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 Gene3D G3DSA:3.30.1490.20 746 804 8.8E-4 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 SUPERFAMILY SSF56059 726 923 2.73E-23 T 06-07-2017 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 Gene3D G3DSA:3.40.50.720 199 340 7.8E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 Pfam PF13380 CoA binding domain 217 345 3.2E-15 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 SUPERFAMILY SSF55729 28 178 6.28E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 364 500 1.4E-36 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 SUPERFAMILY SSF51735 210 340 6.85E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 Gene3D G3DSA:3.40.50.261 504 615 2.1E-9 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 SMART SM00881 212 311 6.5E-26 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 Pfam PF00583 Acetyltransferase (GNAT) family 88 171 2.9E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 SUPERFAMILY SSF52210 340 509 1.09E-34 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LK06_RS25400 dabd005aac8811b08a57aa5c46f86c75 946 Pfam PF13549 ATP-grasp domain 722 929 1.2E-53 T 06-07-2017 LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 Pfam PF00106 short chain dehydrogenase 10 213 8.9E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 Gene3D G3DSA:3.40.50.720 3 278 1.5E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 233 0.0019 T 06-07-2017 LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 SUPERFAMILY SSF51735 2 264 6.02E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 2.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 2.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS08445 9266cc3a24ad8f72fbb11cd10c43a392 312 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 2.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS21195 8f767fbf0112bb5a7075b7c50e22b5e7 277 Gene3D G3DSA:2.40.10.10 176 224 6.8E-7 T 06-07-2017 LK06_RS21195 8f767fbf0112bb5a7075b7c50e22b5e7 277 Pfam PF13365 Trypsin-like peptidase domain 47 215 9.3E-13 T 06-07-2017 LK06_RS21195 8f767fbf0112bb5a7075b7c50e22b5e7 277 SUPERFAMILY SSF50494 25 220 4.83E-18 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS21195 8f767fbf0112bb5a7075b7c50e22b5e7 277 Gene3D G3DSA:2.40.10.10 40 128 3.0E-4 T 06-07-2017 LK06_RS17700 2fbc313a5965b642db31067691855d4c 294 SMART SM00345 21 81 1.4E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17700 2fbc313a5965b642db31067691855d4c 294 Gene3D G3DSA:1.10.10.10 19 87 3.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17700 2fbc313a5965b642db31067691855d4c 294 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 2.6E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17700 2fbc313a5965b642db31067691855d4c 294 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 2.6E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17700 2fbc313a5965b642db31067691855d4c 294 SUPERFAMILY SSF46785 19 85 6.96E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17700 2fbc313a5965b642db31067691855d4c 294 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 73 1.7E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS18270 7514c37ce070304216781ea658036400 473 Gene3D G3DSA:3.40.50.2000 252 450 3.9E-56 T 06-07-2017 LK06_RS18270 7514c37ce070304216781ea658036400 473 Pfam PF00982 Glycosyltransferase family 20 2 467 3.3E-97 T 06-07-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 LK06_RS18270 7514c37ce070304216781ea658036400 473 Gene3D G3DSA:3.40.50.2000 1 251 2.7E-55 T 06-07-2017 LK06_RS18270 7514c37ce070304216781ea658036400 473 SUPERFAMILY SSF53756 2 468 6.91E-105 T 06-07-2017 LK06_RS24125 e6fb98069fba29296cf0e05282a15ef7 261 Pfam PF10370 Domain of unknown function (DUF2437) 2 55 7.3E-11 T 06-07-2017 IPR018833 Domain of unknown function DUF2437 LK06_RS24125 e6fb98069fba29296cf0e05282a15ef7 261 SUPERFAMILY SSF56529 52 258 1.57E-77 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS24125 e6fb98069fba29296cf0e05282a15ef7 261 Gene3D G3DSA:3.90.850.10 51 259 1.7E-91 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS24125 e6fb98069fba29296cf0e05282a15ef7 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 60 258 1.1E-69 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS10110 dfe79fb8e53bddb5e35d8af27cad46c5 406 SMART SM00418 15 97 0.0075 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS10110 dfe79fb8e53bddb5e35d8af27cad46c5 406 Pfam PF00480 ROK family 92 354 8.7E-26 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS10110 dfe79fb8e53bddb5e35d8af27cad46c5 406 Pfam PF12802 MarR family 23 69 6.3E-8 T 06-07-2017 LK06_RS10110 dfe79fb8e53bddb5e35d8af27cad46c5 406 Gene3D G3DSA:3.30.420.40 228 374 8.7E-32 T 06-07-2017 LK06_RS10110 dfe79fb8e53bddb5e35d8af27cad46c5 406 Gene3D G3DSA:3.30.420.40 86 227 4.4E-36 T 06-07-2017 LK06_RS10110 dfe79fb8e53bddb5e35d8af27cad46c5 406 SUPERFAMILY SSF53067 91 397 7.78E-41 T 06-07-2017 LK06_RS10110 dfe79fb8e53bddb5e35d8af27cad46c5 406 SUPERFAMILY SSF46785 18 84 6.54E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS10110 dfe79fb8e53bddb5e35d8af27cad46c5 406 Gene3D G3DSA:1.10.10.10 17 85 8.8E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 Pfam PF01494 FAD binding domain 4 363 4.2E-83 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 Gene3D G3DSA:3.50.50.60 1 163 2.3E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 Gene3D G3DSA:3.50.50.60 296 335 2.3E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 6.0E-47 T 06-07-2017 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 6.0E-47 T 06-07-2017 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 349 6.0E-47 T 06-07-2017 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 6.0E-47 T 06-07-2017 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 349 365 6.0E-47 T 06-07-2017 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 329 6.0E-47 T 06-07-2017 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 Gene3D G3DSA:3.30.9.10 164 291 4.5E-16 T 06-07-2017 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 Gene3D G3DSA:3.30.9.10 346 361 4.5E-16 T 06-07-2017 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 SUPERFAMILY SSF51905 285 369 1.04E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01065 d56de4c60270e06cd16dd111efa4a312 539 SUPERFAMILY SSF51905 3 173 1.04E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS28935 f523eb5af050d3bf1c07881001c11ec4 257 Pfam PF01925 Sulfite exporter TauE/SafE 17 254 2.7E-25 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 SMART SM00421 151 208 3.3E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 SUPERFAMILY SSF46894 138 214 3.74E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 Gene3D G3DSA:1.10.10.10 157 214 1.9E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 7.3E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 7.3E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 7.3E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 SMART SM00448 15 128 3.8E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 Gene3D G3DSA:3.40.50.2300 14 156 6.2E-35 T 06-07-2017 LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 SUPERFAMILY SSF52172 15 142 4.55E-30 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 Pfam PF00072 Response regulator receiver domain 17 129 9.4E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS08465 3ec3626639cdca5eb6a33bad17e67128 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 1.1E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS00790 e7acbdfe54f84a06039a256bd670a1e9 454 Gene3D G3DSA:3.50.50.60 100 320 3.7E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS00790 e7acbdfe54f84a06039a256bd670a1e9 454 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 2.6E-13 T 06-07-2017 LK06_RS00790 e7acbdfe54f84a06039a256bd670a1e9 454 PRINTS PR00419 Adrenodoxin reductase family signature 149 163 2.6E-13 T 06-07-2017 LK06_RS00790 e7acbdfe54f84a06039a256bd670a1e9 454 PIRSF PIRSF000362 1 454 2.3E-161 T 06-07-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 LK06_RS00790 e7acbdfe54f84a06039a256bd670a1e9 454 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 171 1.3E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS00790 e7acbdfe54f84a06039a256bd670a1e9 454 SUPERFAMILY SSF51971 4 215 2.47E-55 T 06-07-2017 LK06_RS00790 e7acbdfe54f84a06039a256bd670a1e9 454 SUPERFAMILY SSF51971 264 321 2.47E-55 T 06-07-2017 LK06_RS00790 e7acbdfe54f84a06039a256bd670a1e9 454 Gene3D G3DSA:3.40.50.720 321 450 7.2E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00790 e7acbdfe54f84a06039a256bd670a1e9 454 Gene3D G3DSA:3.40.50.720 4 99 7.2E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 PRINTS PR01046 Prolyl-tRNA synthetase signature 74 92 5.8E-16 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 PRINTS PR01046 Prolyl-tRNA synthetase signature 140 148 5.8E-16 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 PRINTS PR01046 Prolyl-tRNA synthetase signature 110 121 5.8E-16 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 PRINTS PR01046 Prolyl-tRNA synthetase signature 150 161 5.8E-16 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 Pfam PF03129 Anticodon binding domain 478 566 2.3E-14 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 Gene3D G3DSA:3.30.930.10 17 240 7.5E-94 T 06-07-2017 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 Gene3D G3DSA:3.30.930.10 391 471 7.5E-94 T 06-07-2017 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 SUPERFAMILY SSF55681 409 480 2.59E-89 T 06-07-2017 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 SUPERFAMILY SSF55681 16 243 2.59E-89 T 06-07-2017 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 8 562 4.4E-173 T 06-07-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 Hamap MF_01569 Proline--tRNA ligase [proS]. 7 568 36.323 T 06-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 Pfam PF04073 Aminoacyl-tRNA editing domain 262 381 1.7E-27 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 Gene3D G3DSA:3.40.50.800 472 567 7.4E-21 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 SUPERFAMILY SSF55826 250 401 1.57E-22 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 Gene3D G3DSA:3.90.960.10 253 389 1.1E-20 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 SUPERFAMILY SSF52954 463 566 6.05E-23 T 06-07-2017 IPR004154 Anticodon-binding LK06_RS24725 3206aef6dde6bd6b6fb85aa67c5270f7 568 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 100 460 7.2E-41 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS05735 053082daaef61bd995ee50d368fa65b5 460 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 45 78 - T 06-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 LK06_RS05735 053082daaef61bd995ee50d368fa65b5 460 Pfam PF08031 Berberine and berberine like 425 458 3.5E-8 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 LK06_RS05735 053082daaef61bd995ee50d368fa65b5 460 Gene3D G3DSA:3.30.465.10 102 212 2.4E-15 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS05735 053082daaef61bd995ee50d368fa65b5 460 Gene3D G3DSA:3.30.43.10 37 101 1.9E-10 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS05735 053082daaef61bd995ee50d368fa65b5 460 Pfam PF01565 FAD binding domain 45 178 9.6E-29 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LK06_RS05735 053082daaef61bd995ee50d368fa65b5 460 SUPERFAMILY SSF56176 18 210 2.29E-50 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 Gene3D G3DSA:3.30.450.20 294 388 4.1E-13 T 06-07-2017 LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 SMART SM00065 441 587 0.005 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 SMART SM00091 289 355 5.8E-5 T 06-07-2017 IPR000014 PAS domain LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 SMART SM00091 176 244 91.0 T 06-07-2017 IPR000014 PAS domain LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 Gene3D G3DSA:3.30.450.20 184 264 2.5E-6 T 06-07-2017 LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 SUPERFAMILY SSF55785 295 368 3.14E-11 T 06-07-2017 IPR000014 PAS domain LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 Pfam PF13185 GAF domain 441 578 1.2E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 SUPERFAMILY SSF81606 622 823 1.18E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 SUPERFAMILY SSF55781 446 587 3.49E-15 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 Pfam PF08448 PAS fold 296 385 4.3E-13 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 634 826 3.5E-50 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 Gene3D G3DSA:3.30.450.40 7 149 1.4E-4 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 Gene3D G3DSA:3.30.450.40 435 583 7.1E-12 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00815 3b683170aa324028963643f0a04a89d5 834 SMART SM00331 605 826 1.8E-39 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS10980 c10a19442783bbfdb6b72f6806ce0e55 377 SUPERFAMILY SSF117892 202 323 3.66E-6 T 06-07-2017 IPR001107 Band 7 domain LK06_RS10980 c10a19442783bbfdb6b72f6806ce0e55 377 Pfam PF01145 SPFH domain / Band 7 family 169 329 7.2E-14 T 06-07-2017 IPR001107 Band 7 domain LK06_RS06485 4b9ce354a711b5520114f48675324f20 256 Gene3D G3DSA:1.10.10.10 30 133 8.8E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06485 4b9ce354a711b5520114f48675324f20 256 Pfam PF01022 Bacterial regulatory protein, arsR family 28 72 9.5E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS06485 4b9ce354a711b5520114f48675324f20 256 SUPERFAMILY SSF46785 29 216 1.83E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Gene3D G3DSA:3.40.50.980 177 333 1.3E-47 T 06-07-2017 LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 SUPERFAMILY SSF53474 713 1008 2.43E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 ProSitePatterns PS00455 Putative AMP-binding domain signature. 327 338 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Pfam PF00550 Phosphopantetheine attachment site 685 747 8.1E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Gene3D G3DSA:3.40.50.980 334 479 1.7E-43 T 06-07-2017 LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Gene3D G3DSA:1.10.1200.10 687 750 5.2E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Pfam PF00975 Thioesterase domain 775 1011 4.9E-18 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Gene3D G3DSA:2.30.38.10 494 573 1.4E-23 T 06-07-2017 LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 205 607 2.7E-115 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 SMART SM00823 Phosphopantetheine attachment site 684 751 0.0013 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Gene3D G3DSA:3.30.300.30 579 686 7.2E-34 T 06-07-2017 LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Gene3D G3DSA:3.40.50.1820 762 879 1.5E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Gene3D G3DSA:3.40.50.1820 942 1011 1.5E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 SMART SM00824 Thioesterase 777 1010 0.0013 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Pfam PF13193 AMP-binding enzyme C-terminal domain 591 659 9.1E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 Pfam PF00501 AMP-binding enzyme 184 583 4.0E-93 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS21070 19f6c9a3162993f9fac060d95592ede7 1018 SUPERFAMILY SSF56801 145 697 2.75E-148 T 06-07-2017 LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 Gene3D G3DSA:3.40.50.10260 2 199 2.0E-56 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 PIRSF PIRSF017184 1 470 2.5E-96 T 06-07-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 4 199 19.299 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 SUPERFAMILY SSF64153 2 231 7.06E-48 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 Gene3D G3DSA:3.40.1190.20 206 467 1.7E-74 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 210 470 19.305 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 214 466 8.1E-43 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 Pfam PF01256 Carbohydrate kinase 233 452 6.0E-43 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 SUPERFAMILY SSF53613 210 467 1.94E-51 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 14 198 3.1E-29 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 LK06_RS20050 d91708ff7e053ff553681f08b25bbe14 470 Pfam PF03853 YjeF-related protein N-terminus 19 178 9.5E-40 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 LK06_RS01495 fa9d3791f40563ac9079e1beb4c162f1 187 SUPERFAMILY SSF52218 4 177 5.37E-43 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS01495 fa9d3791f40563ac9079e1beb4c162f1 187 Gene3D G3DSA:3.40.50.360 3 178 3.5E-48 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS01495 fa9d3791f40563ac9079e1beb4c162f1 187 Pfam PF03358 NADPH-dependent FMN reductase 4 148 5.4E-36 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 LK06_RS08045 1b9f7952b6c1cc953957b0eb1afd5a9f 343 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 219 235 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 LK06_RS08045 1b9f7952b6c1cc953957b0eb1afd5a9f 343 SUPERFAMILY SSF54368 6 88 3.92E-10 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08045 1b9f7952b6c1cc953957b0eb1afd5a9f 343 ProSitePatterns PS00180 Glutamine synthetase signature 1. 41 58 - T 06-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 LK06_RS08045 1b9f7952b6c1cc953957b0eb1afd5a9f 343 SMART SM01230 89 333 1.4E-46 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08045 1b9f7952b6c1cc953957b0eb1afd5a9f 343 Pfam PF00120 Glutamine synthetase, catalytic domain 99 236 2.7E-11 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08045 1b9f7952b6c1cc953957b0eb1afd5a9f 343 SUPERFAMILY SSF55931 91 338 1.08E-62 T 06-07-2017 LK06_RS08045 1b9f7952b6c1cc953957b0eb1afd5a9f 343 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 5 82 9.4E-14 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08045 1b9f7952b6c1cc953957b0eb1afd5a9f 343 Gene3D G3DSA:3.30.590.10 93 338 2.2E-53 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LK06_RS25630 c3ddd1eea37a1114a50f52cfed8f4f65 153 Pfam PF00872 Transposase, Mutator family 2 119 6.4E-34 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 Pfam PF09334 tRNA synthetases class I (M) 70 173 1.6E-13 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 73 83 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 Gene3D G3DSA:3.40.50.620 225 301 4.2E-136 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 Gene3D G3DSA:3.40.50.620 730 759 4.2E-136 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 Gene3D G3DSA:3.40.50.620 26 176 4.2E-136 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 Gene3D G3DSA:3.40.50.620 525 697 4.2E-136 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 SUPERFAMILY SSF52374 226 304 7.8E-114 T 06-07-2017 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 SUPERFAMILY SSF52374 28 177 7.8E-114 T 06-07-2017 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 SUPERFAMILY SSF52374 516 779 7.8E-114 T 06-07-2017 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 SUPERFAMILY SSF50677 301 519 4.71E-45 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 Gene3D G3DSA:3.90.740.10 302 524 1.2E-50 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 Pfam PF08264 Anticodon-binding domain of tRNA 805 921 5.3E-14 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 Gene3D G3DSA:1.10.730.10 760 895 7.0E-34 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 PRINTS PR00985 Leucyl-tRNA synthetase signature 293 312 1.8E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 PRINTS PR00985 Leucyl-tRNA synthetase signature 648 670 1.8E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 PRINTS PR00985 Leucyl-tRNA synthetase signature 157 174 1.8E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 PRINTS PR00985 Leucyl-tRNA synthetase signature 231 247 1.8E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 PRINTS PR00985 Leucyl-tRNA synthetase signature 600 618 1.8E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 PRINTS PR00985 Leucyl-tRNA synthetase signature 681 691 1.8E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 PRINTS PR00985 Leucyl-tRNA synthetase signature 264 277 1.8E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 299 503 2.0E-60 T 06-07-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 SUPERFAMILY SSF47323 775 958 7.1E-28 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 225 958 3.7E-219 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LK06_RS09575 7917a080ba459ed85cb0714f8c974d32 960 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 23 959 21.296 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LK06_RS07305 0fa3a458b41592ac62c34c4f16ca8e07 457 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 364 388 - T 06-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 LK06_RS07305 0fa3a458b41592ac62c34c4f16ca8e07 457 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 48 405 1.9E-112 T 06-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 LK06_RS07305 0fa3a458b41592ac62c34c4f16ca8e07 457 Pfam PF01098 Cell cycle protein 54 404 5.0E-92 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 LK06_RS08150 ed31a8a9fc693d2cf921c21a6c1524de 148 Pfam PF02082 Transcriptional regulator 1 81 1.9E-17 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type LK06_RS08150 ed31a8a9fc693d2cf921c21a6c1524de 148 SUPERFAMILY SSF46785 5 132 7.39E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08150 ed31a8a9fc693d2cf921c21a6c1524de 148 Gene3D G3DSA:1.10.10.10 1 131 1.4E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08150 ed31a8a9fc693d2cf921c21a6c1524de 148 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 129 1.7E-23 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type LK06_RS21135 ea5aa342083bc7145490c1f9a3f948d9 256 SMART SM00824 Thioesterase 25 243 0.0011 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 LK06_RS21135 ea5aa342083bc7145490c1f9a3f948d9 256 Gene3D G3DSA:3.40.50.1820 17 247 3.5E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21135 ea5aa342083bc7145490c1f9a3f948d9 256 SUPERFAMILY SSF53474 6 247 3.3E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21135 ea5aa342083bc7145490c1f9a3f948d9 256 Pfam PF00975 Thioesterase domain 23 248 1.6E-43 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS25525 f8bab1e1dee78e059df4918eb64ab69c 442 Gene3D G3DSA:3.40.50.150 245 436 1.4E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25525 f8bab1e1dee78e059df4918eb64ab69c 442 SUPERFAMILY SSF50249 8 56 3.48E-10 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS25525 f8bab1e1dee78e059df4918eb64ab69c 442 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 420 430 - T 06-07-2017 IPR030391 RNA methyltransferase TrmA, conserved site LK06_RS25525 f8bab1e1dee78e059df4918eb64ab69c 442 SUPERFAMILY SSF53335 75 437 1.91E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25525 f8bab1e1dee78e059df4918eb64ab69c 442 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 261 339 1.9E-4 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 LK06_RS25525 f8bab1e1dee78e059df4918eb64ab69c 442 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 362 436 5.7E-10 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 LK06_RS25525 f8bab1e1dee78e059df4918eb64ab69c 442 Gene3D G3DSA:2.40.50.140 10 85 6.8E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS25525 f8bab1e1dee78e059df4918eb64ab69c 442 Pfam PF01938 TRAM domain 7 67 2.4E-14 T 06-07-2017 IPR002792 TRAM domain LK06_RS22380 feb36c1388a491bdabe80421718dfa7f 287 Pfam PF04542 Sigma-70 region 2 103 166 6.9E-18 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22380 feb36c1388a491bdabe80421718dfa7f 287 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 86 273 5.9E-109 T 06-07-2017 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22380 feb36c1388a491bdabe80421718dfa7f 287 SUPERFAMILY SSF88659 201 263 5.79E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22380 feb36c1388a491bdabe80421718dfa7f 287 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 121 152 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22380 feb36c1388a491bdabe80421718dfa7f 287 SUPERFAMILY SSF88946 94 181 4.97E-24 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22380 feb36c1388a491bdabe80421718dfa7f 287 Gene3D G3DSA:1.10.1740.10 91 168 2.6E-28 T 06-07-2017 LK06_RS22380 feb36c1388a491bdabe80421718dfa7f 287 Gene3D G3DSA:1.10.10.10 201 265 5.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22380 feb36c1388a491bdabe80421718dfa7f 287 Pfam PF08281 Sigma-70, region 4 208 258 9.1E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS22380 feb36c1388a491bdabe80421718dfa7f 287 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 101 261 2.9E-26 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS04220 a53ffe1216ec1edda70761273766608d 219 SMART SM00756 28 173 2.7E-50 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 LK06_RS04220 a53ffe1216ec1edda70761273766608d 219 Pfam PF07884 Vitamin K epoxide reductase family 34 169 5.6E-27 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 LK06_RS29135 f1c0a1ab68d8aee75a582e25d391328f 115 Gene3D G3DSA:1.10.10.10 20 84 5.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29135 f1c0a1ab68d8aee75a582e25d391328f 115 SMART SM00421 28 85 2.3E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS29135 f1c0a1ab68d8aee75a582e25d391328f 115 Pfam PF00196 Bacterial regulatory proteins, luxR family 30 83 3.4E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS29135 f1c0a1ab68d8aee75a582e25d391328f 115 SUPERFAMILY SSF46894 22 84 2.86E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS29135 f1c0a1ab68d8aee75a582e25d391328f 115 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 45 61 2.3E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS29135 f1c0a1ab68d8aee75a582e25d391328f 115 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 31 45 2.3E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS29135 f1c0a1ab68d8aee75a582e25d391328f 115 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 61 73 2.3E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26435 f9482937ee24aea6285495be12e06b9b 351 Gene3D G3DSA:3.40.50.1820 38 189 1.3E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS26435 f9482937ee24aea6285495be12e06b9b 351 Gene3D G3DSA:3.40.50.1820 265 346 1.3E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS26435 f9482937ee24aea6285495be12e06b9b 351 SUPERFAMILY SSF53474 39 189 1.06E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS26435 f9482937ee24aea6285495be12e06b9b 351 SUPERFAMILY SSF53474 267 348 1.06E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS26435 f9482937ee24aea6285495be12e06b9b 351 Pfam PF12697 Alpha/beta hydrolase family 74 335 7.9E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS21675 26fa985f7d5b66af361e34dd30bbc19e 243 Pfam PF13646 HEAT repeats 50 105 2.3E-6 T 06-07-2017 LK06_RS21675 26fa985f7d5b66af361e34dd30bbc19e 243 SUPERFAMILY SSF48371 20 103 8.16E-11 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS21675 26fa985f7d5b66af361e34dd30bbc19e 243 Gene3D G3DSA:1.25.10.10 32 128 8.7E-9 T 06-07-2017 IPR011989 Armadillo-like helical LK06_RS06855 9f994305cdec5ae91c913918e414f133 278 Gene3D G3DSA:3.40.50.150 34 266 8.9E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS06855 9f994305cdec5ae91c913918e414f133 278 SUPERFAMILY SSF53335 34 257 9.81E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS06855 9f994305cdec5ae91c913918e414f133 278 Pfam PF08241 Methyltransferase domain 85 177 9.5E-19 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 ProSitePatterns PS00211 ABC transporters family signature. 347 361 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 Gene3D G3DSA:1.10.8.280 159 270 1.7E-23 T 06-07-2017 LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 ProSitePatterns PS00211 ABC transporters family signature. 671 685 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 SUPERFAMILY SSF52540 476 753 5.94E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 Gene3D G3DSA:3.40.50.300 9 56 8.7E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 Gene3D G3DSA:3.40.50.300 338 455 8.7E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 Gene3D G3DSA:3.40.50.300 662 779 2.6E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 Gene3D G3DSA:3.40.50.300 476 527 2.6E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 Gene3D G3DSA:1.20.1580.10 98 158 4.0E-30 T 06-07-2017 LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 Gene3D G3DSA:1.20.1580.10 529 661 2.0E-44 T 06-07-2017 LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 Gene3D G3DSA:1.20.1580.10 271 337 4.0E-30 T 06-07-2017 LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 Pfam PF00005 ABC transporter 481 701 2.9E-8 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 SUPERFAMILY SSF52540 9 57 7.17E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01570 dd52e938c80a8d62d6125978f0149029 782 SUPERFAMILY SSF52540 285 429 7.17E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27730 28e83a9b28b64f047f4c70c4598c16b5 375 Gene3D G3DSA:3.90.1200.10 123 264 8.4E-9 T 06-07-2017 LK06_RS27730 28e83a9b28b64f047f4c70c4598c16b5 375 SUPERFAMILY SSF56112 35 312 3.91E-20 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS03305 b5eb37d41d97c6262f2a23b7fa7e80e4 214 Pfam PF00857 Isochorismatase family 16 202 2.6E-23 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS03305 b5eb37d41d97c6262f2a23b7fa7e80e4 214 Gene3D G3DSA:3.40.50.850 11 209 2.9E-37 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS03305 b5eb37d41d97c6262f2a23b7fa7e80e4 214 SUPERFAMILY SSF52499 9 207 8.37E-38 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS30810 066d71ffdb5413d12b2eeee55cb000be 231 Pfam PF00075 RNase H 7 150 2.7E-30 T 06-07-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 LK06_RS30810 066d71ffdb5413d12b2eeee55cb000be 231 Hamap MF_00042 Ribonuclease H [rnhA]. 6 159 36.077 T 06-07-2017 IPR022892 Ribonuclease H GO:0004523 LK06_RS30810 066d71ffdb5413d12b2eeee55cb000be 231 SUPERFAMILY SSF53098 7 152 1.64E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS30810 066d71ffdb5413d12b2eeee55cb000be 231 Gene3D G3DSA:3.30.420.10 7 153 2.1E-46 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS18290 5855d56ab4a8a4e766b260cd564f152c 91 SUPERFAMILY SSF54285 1 91 9.0E-24 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp LK06_RS18290 5855d56ab4a8a4e766b260cd564f152c 91 Pfam PF02597 ThiS family 5 91 7.4E-18 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 LK06_RS18290 5855d56ab4a8a4e766b260cd564f152c 91 Gene3D G3DSA:3.10.20.30 3 89 8.8E-30 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS08625 be761c90f13ee0190f7c8a518a6707c5 223 SUPERFAMILY SSF53335 5 219 3.19E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS08625 be761c90f13ee0190f7c8a518a6707c5 223 Pfam PF01596 O-methyltransferase 35 190 3.0E-38 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 LK06_RS08625 be761c90f13ee0190f7c8a518a6707c5 223 Gene3D G3DSA:3.40.50.150 5 221 2.5E-60 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS04410 4280051d492196c34c113bc0d3d57e98 483 SUPERFAMILY SSF47413 9 77 3.22E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS04410 4280051d492196c34c113bc0d3d57e98 483 Gene3D G3DSA:1.10.260.40 25 72 1.1E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS04410 4280051d492196c34c113bc0d3d57e98 483 Pfam PF13560 Helix-turn-helix domain 10 65 3.4E-6 T 06-07-2017 LK06_RS04410 4280051d492196c34c113bc0d3d57e98 483 SMART SM00530 13 72 0.0012 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS13480 7f56dbf4cfd18c1129e240c4393c1cd5 390 PRINTS PR01270 Histone deacetylase superfamily signature 161 176 4.6E-18 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LK06_RS13480 7f56dbf4cfd18c1129e240c4393c1cd5 390 PRINTS PR01270 Histone deacetylase superfamily signature 128 151 4.6E-18 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LK06_RS13480 7f56dbf4cfd18c1129e240c4393c1cd5 390 PRINTS PR01270 Histone deacetylase superfamily signature 247 257 4.6E-18 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LK06_RS13480 7f56dbf4cfd18c1129e240c4393c1cd5 390 Gene3D G3DSA:3.40.800.20 4 350 1.6E-88 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LK06_RS13480 7f56dbf4cfd18c1129e240c4393c1cd5 390 SUPERFAMILY SSF52768 6 350 6.23E-101 T 06-07-2017 LK06_RS13480 7f56dbf4cfd18c1129e240c4393c1cd5 390 Pfam PF00850 Histone deacetylase domain 22 316 7.8E-70 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LK06_RS13480 7f56dbf4cfd18c1129e240c4393c1cd5 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 307 326 1.6E-9 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 LK06_RS13480 7f56dbf4cfd18c1129e240c4393c1cd5 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 105 118 1.6E-9 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 LK06_RS13480 7f56dbf4cfd18c1129e240c4393c1cd5 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 1.6E-9 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 LK06_RS13480 7f56dbf4cfd18c1129e240c4393c1cd5 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 84 98 1.6E-9 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 LK06_RS31765 e721fceae4a7544c4f07edb338a17006 362 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 192 301 2.1E-20 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS31765 e721fceae4a7544c4f07edb338a17006 362 Gene3D G3DSA:3.40.47.10 201 360 7.8E-32 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31765 e721fceae4a7544c4f07edb338a17006 362 SMART SM00825 Beta-ketoacyl synthase 4 362 1.8E-5 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS31765 e721fceae4a7544c4f07edb338a17006 362 SUPERFAMILY SSF53901 1 188 4.45E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31765 e721fceae4a7544c4f07edb338a17006 362 SUPERFAMILY SSF53901 151 360 2.88E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31765 e721fceae4a7544c4f07edb338a17006 362 Gene3D G3DSA:3.40.47.10 103 196 4.4E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS31765 e721fceae4a7544c4f07edb338a17006 362 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 103 181 3.0E-7 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 SUPERFAMILY SSF53223 1 121 3.36E-36 T 06-07-2017 LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.2E-34 T 06-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 Gene3D G3DSA:3.40.50.720 139 264 4.5E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.3E-62 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.3E-62 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 1.3E-62 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.3E-62 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 1.3E-62 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.3E-62 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 282 5.5E-61 T 06-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 SUPERFAMILY SSF51735 122 281 1.31E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 36.079 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 LK06_RS20380 ad8d449b53c62cfb1741a6b312bb5719 284 Gene3D G3DSA:3.40.192.10 7 138 3.8E-44 T 06-07-2017 LK06_RS06845 fb0e5651b67f58f137d7def11436367e 312 Gene3D G3DSA:1.10.287.100 237 275 2.5E-8 T 06-07-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 LK06_RS06845 fb0e5651b67f58f137d7def11436367e 312 Pfam PF09754 PAC2 family 35 253 1.3E-37 T 06-07-2017 IPR019151 Proteasome assembly chaperone 2 LK06_RS06845 fb0e5651b67f58f137d7def11436367e 312 PIRSF PIRSF028754 12 312 3.1E-110 T 06-07-2017 IPR008492 Protein of unknown function DUF774 LK06_RS06845 fb0e5651b67f58f137d7def11436367e 312 SUPERFAMILY SSF159659 26 276 2.09E-70 T 06-07-2017 LK06_RS04305 e3b642dccb76154f1c65fdce36a60aa6 202 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 7 192 37.377 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 LK06_RS04305 e3b642dccb76154f1c65fdce36a60aa6 202 PIRSF PIRSF005639 1 197 3.4E-73 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 LK06_RS04305 e3b642dccb76154f1c65fdce36a60aa6 202 SUPERFAMILY SSF52317 6 194 2.11E-53 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS04305 e3b642dccb76154f1c65fdce36a60aa6 202 Pfam PF01174 SNO glutamine amidotransferase family 9 193 3.3E-59 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 LK06_RS04305 e3b642dccb76154f1c65fdce36a60aa6 202 Gene3D G3DSA:3.40.50.880 4 197 7.6E-79 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS04305 e3b642dccb76154f1c65fdce36a60aa6 202 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 7 191 2.7E-83 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 LK06_RS04305 e3b642dccb76154f1c65fdce36a60aa6 202 ProSitePatterns PS01236 PdxT/SNO family family signature. 44 54 - T 06-07-2017 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 LK06_RS30560 9164fa8bfa18414590ed67ebc010c835 500 SUPERFAMILY SSF56801 8 496 2.22E-148 T 06-07-2017 LK06_RS30560 9164fa8bfa18414590ed67ebc010c835 500 Gene3D G3DSA:3.30.300.30 399 495 1.0E-28 T 06-07-2017 LK06_RS30560 9164fa8bfa18414590ed67ebc010c835 500 Pfam PF00501 AMP-binding enzyme 14 404 1.6E-96 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS30560 9164fa8bfa18414590ed67ebc010c835 500 Gene3D G3DSA:3.40.50.980 8 172 5.0E-38 T 06-07-2017 LK06_RS30560 9164fa8bfa18414590ed67ebc010c835 500 Gene3D G3DSA:3.40.50.980 173 313 7.2E-36 T 06-07-2017 LK06_RS30560 9164fa8bfa18414590ed67ebc010c835 500 Gene3D G3DSA:2.30.38.10 323 397 2.6E-27 T 06-07-2017 LK06_RS30560 9164fa8bfa18414590ed67ebc010c835 500 Pfam PF13193 AMP-binding enzyme C-terminal domain 414 486 3.3E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS02695 8caedc91122372512f7f7e471942ce3f 69 Gene3D G3DSA:3.90.820.10 11 67 2.1E-27 T 06-07-2017 LK06_RS02695 8caedc91122372512f7f7e471942ce3f 69 Pfam PF03621 MbtH-like protein 2 52 3.1E-23 T 06-07-2017 IPR005153 MbtH-like protein LK06_RS02695 8caedc91122372512f7f7e471942ce3f 69 SMART SM00923 3 53 2.5E-26 T 06-07-2017 IPR005153 MbtH-like protein LK06_RS02695 8caedc91122372512f7f7e471942ce3f 69 SUPERFAMILY SSF160582 2 66 6.15E-28 T 06-07-2017 LK06_RS23220 69cc4213d254261847d624506397186d 305 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 94 105 - T 06-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 LK06_RS23220 69cc4213d254261847d624506397186d 305 Pfam PF08544 GHMP kinases C terminal 222 279 7.7E-7 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain LK06_RS23220 69cc4213d254261847d624506397186d 305 SUPERFAMILY SSF54211 11 156 4.02E-30 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS23220 69cc4213d254261847d624506397186d 305 PIRSF PIRSF000676 7 301 8.5E-87 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 LK06_RS23220 69cc4213d254261847d624506397186d 305 Pfam PF00288 GHMP kinases N terminal domain 88 151 4.2E-12 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 LK06_RS23220 69cc4213d254261847d624506397186d 305 Gene3D G3DSA:3.30.230.10 10 160 1.4E-58 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS23220 69cc4213d254261847d624506397186d 305 PRINTS PR00958 Homoserine kinase signature 18 33 6.7E-34 T 06-07-2017 LK06_RS23220 69cc4213d254261847d624506397186d 305 PRINTS PR00958 Homoserine kinase signature 177 194 6.7E-34 T 06-07-2017 LK06_RS23220 69cc4213d254261847d624506397186d 305 PRINTS PR00958 Homoserine kinase signature 138 151 6.7E-34 T 06-07-2017 LK06_RS23220 69cc4213d254261847d624506397186d 305 PRINTS PR00958 Homoserine kinase signature 254 269 6.7E-34 T 06-07-2017 LK06_RS23220 69cc4213d254261847d624506397186d 305 PRINTS PR00958 Homoserine kinase signature 101 116 6.7E-34 T 06-07-2017 LK06_RS23220 69cc4213d254261847d624506397186d 305 Gene3D G3DSA:3.30.70.890 171 292 1.0E-34 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain LK06_RS23220 69cc4213d254261847d624506397186d 305 Hamap MF_00384 Homoserine kinase [thrB]. 11 300 29.916 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 LK06_RS23220 69cc4213d254261847d624506397186d 305 TIGRFAM TIGR00191 thrB: homoserine kinase 11 280 2.8E-65 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 LK06_RS23220 69cc4213d254261847d624506397186d 305 SUPERFAMILY SSF55060 173 285 6.71E-28 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain LK06_RS06180 dfc06e38d6b8e015256d59db4032c13c 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 254 1.7E-36 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS06180 dfc06e38d6b8e015256d59db4032c13c 267 SUPERFAMILY SSF52096 15 259 3.73E-60 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS06180 dfc06e38d6b8e015256d59db4032c13c 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 123 143 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 LK06_RS06180 dfc06e38d6b8e015256d59db4032c13c 267 Gene3D G3DSA:3.90.226.10 14 255 2.6E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS04450 a180d2b5f10e35317f42db70dc12bbab 169 SMART SM00857 16 168 2.6E-26 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 LK06_RS04450 a180d2b5f10e35317f42db70dc12bbab 169 ProSitePatterns PS00397 Site-specific recombinases active site. 19 27 - T 06-07-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 LK06_RS04450 a180d2b5f10e35317f42db70dc12bbab 169 Pfam PF00239 Resolvase, N terminal domain 17 169 3.2E-26 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 LK06_RS04450 a180d2b5f10e35317f42db70dc12bbab 169 SUPERFAMILY SSF53041 17 169 1.57E-24 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 LK06_RS04450 a180d2b5f10e35317f42db70dc12bbab 169 Gene3D G3DSA:3.40.50.1390 16 149 2.3E-20 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 LK06_RS01375 595ca6824d3faf0042965b16b2a66d7f 288 Pfam PF13560 Helix-turn-helix domain 9 88 2.9E-16 T 06-07-2017 LK06_RS01375 595ca6824d3faf0042965b16b2a66d7f 288 SUPERFAMILY SSF47413 9 83 9.78E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS01375 595ca6824d3faf0042965b16b2a66d7f 288 Gene3D G3DSA:1.10.260.40 8 83 2.5E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS01375 595ca6824d3faf0042965b16b2a66d7f 288 SMART SM00530 13 85 5.5E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS11680 17a0ae1e0dcae0328f2d92c7ff32df34 308 Pfam PF01061 ABC-2 type transporter 63 266 4.6E-16 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS24490 1d543519fd9825a4b9be8fac8e02ab15 225 Pfam PF01551 Peptidase family M23 69 164 1.1E-15 T 06-07-2017 IPR016047 Peptidase M23 LK06_RS24490 1d543519fd9825a4b9be8fac8e02ab15 225 Gene3D G3DSA:2.70.70.10 32 169 7.2E-25 T 06-07-2017 LK06_RS24490 1d543519fd9825a4b9be8fac8e02ab15 225 SUPERFAMILY SSF51261 45 168 3.09E-18 T 06-07-2017 IPR011055 Duplicated hybrid motif LK06_RS05310 9fb0144243f8dbd0b4dc93b8d1361990 929 Pfam PF01804 Penicillin amidase 139 916 4.4E-118 T 06-07-2017 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 LK06_RS05310 9fb0144243f8dbd0b4dc93b8d1361990 929 Gene3D G3DSA:3.60.20.10 405 484 1.6E-60 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS05310 9fb0144243f8dbd0b4dc93b8d1361990 929 Gene3D G3DSA:3.60.20.10 569 808 1.6E-60 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS05310 9fb0144243f8dbd0b4dc93b8d1361990 929 SUPERFAMILY SSF56235 138 343 4.12E-101 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS05310 9fb0144243f8dbd0b4dc93b8d1361990 929 SUPERFAMILY SSF56235 397 800 4.12E-101 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS05310 9fb0144243f8dbd0b4dc93b8d1361990 929 Gene3D G3DSA:1.10.439.10 136 299 2.7E-36 T 06-07-2017 IPR023343 Penicillin amidase type, domain1 GO:0016811 LK06_RS23460 4a6f5ae8cd39e9c4892fd83173695385 210 Gene3D G3DSA:3.60.160.10 7 208 2.1E-44 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS23460 4a6f5ae8cd39e9c4892fd83173695385 210 SUPERFAMILY SSF51219 7 207 5.23E-47 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain LK06_RS23460 4a6f5ae8cd39e9c4892fd83173695385 210 Pfam PF01987 Mitochondrial biogenesis AIM24 6 200 6.4E-35 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 PRINTS PR01183 Ribonucleotide reductase large chain signature 505 527 1.4E-48 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 PRINTS PR01183 Ribonucleotide reductase large chain signature 533 556 1.4E-48 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 PRINTS PR01183 Ribonucleotide reductase large chain signature 428 439 1.4E-48 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 PRINTS PR01183 Ribonucleotide reductase large chain signature 467 490 1.4E-48 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 PRINTS PR01183 Ribonucleotide reductase large chain signature 598 625 1.4E-48 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 PRINTS PR01183 Ribonucleotide reductase large chain signature 296 315 1.4E-48 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 143 747 1.8E-223 T 06-07-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 140 216 8.6E-20 T 06-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 SUPERFAMILY SSF48168 22 218 1.96E-43 T 06-07-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 Gene3D G3DSA:3.20.70.20 598 643 9.8E-78 T 06-07-2017 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 Gene3D G3DSA:3.20.70.20 141 342 9.8E-78 T 06-07-2017 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 Gene3D G3DSA:3.20.70.20 392 553 9.8E-78 T 06-07-2017 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 SUPERFAMILY SSF51998 219 647 6.1E-175 T 06-07-2017 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 SUPERFAMILY SSF51998 678 748 6.1E-175 T 06-07-2017 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 Pfam PF02867 Ribonucleotide reductase, barrel domain 220 743 8.1E-175 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22425 4cfe4355e1f1f86b034c059c1cafca66 785 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 587 609 - T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS00740 6ed13b3f3a86859695b72ab051763329 329 Gene3D G3DSA:3.20.20.100 2 318 7.9E-116 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS00740 6ed13b3f3a86859695b72ab051763329 329 Pfam PF00248 Aldo/keto reductase family 14 309 1.4E-79 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS00740 6ed13b3f3a86859695b72ab051763329 329 SUPERFAMILY SSF51430 8 310 4.06E-103 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS12225 5a8ad22ff3f0d78990188b882418f846 201 SUPERFAMILY SSF54211 102 181 8.09E-25 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS12225 5a8ad22ff3f0d78990188b882418f846 201 Gene3D G3DSA:3.30.230.10 101 181 2.1E-32 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS12225 5a8ad22ff3f0d78990188b882418f846 201 Gene3D G3DSA:3.30.160.20 34 95 2.1E-28 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain LK06_RS12225 5a8ad22ff3f0d78990188b882418f846 201 Pfam PF03719 Ribosomal protein S5, C-terminal domain 110 180 6.6E-29 T 06-07-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 LK06_RS12225 5a8ad22ff3f0d78990188b882418f846 201 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 32 186 8.3E-68 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 LK06_RS12225 5a8ad22ff3f0d78990188b882418f846 201 Pfam PF00333 Ribosomal protein S5, N-terminal domain 36 98 5.2E-27 T 06-07-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 LK06_RS12225 5a8ad22ff3f0d78990188b882418f846 201 SUPERFAMILY SSF54768 33 99 1.46E-21 T 06-07-2017 LK06_RS12225 5a8ad22ff3f0d78990188b882418f846 201 ProSitePatterns PS00585 Ribosomal protein S5 signature. 51 83 - T 06-07-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site LK06_RS12225 5a8ad22ff3f0d78990188b882418f846 201 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 186 34.536 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 LK06_RS20440 a86131fc5a5521e492401e9a8b068a65 133 Gene3D G3DSA:1.20.1290.10 2 130 7.4E-44 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS20440 a86131fc5a5521e492401e9a8b068a65 133 Pfam PF02627 Carboxymuconolactone decarboxylase family 10 77 4.4E-14 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS20440 a86131fc5a5521e492401e9a8b068a65 133 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 14 60 1.1E-14 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS20440 a86131fc5a5521e492401e9a8b068a65 133 SUPERFAMILY SSF69118 3 129 1.03E-36 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 Gene3D G3DSA:1.25.40.10 74 129 5.7E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 SUPERFAMILY SSF48452 321 431 5.69E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 Gene3D G3DSA:1.10.260.40 4 68 1.8E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 SUPERFAMILY SSF48452 195 318 1.05E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 SMART SM00028 119 152 0.46 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 SMART SM00028 240 273 130.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 SMART SM00028 280 313 36.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 SMART SM00028 360 393 5.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 SMART SM00028 400 433 11.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 Pfam PF13432 Tetratricopeptide repeat 84 148 3.2E-6 T 06-07-2017 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 Pfam PF13432 Tetratricopeptide repeat 251 309 0.014 T 06-07-2017 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 Pfam PF13432 Tetratricopeptide repeat 326 387 0.0047 T 06-07-2017 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 SMART SM00530 13 67 6.3E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 SUPERFAMILY SSF48452 83 187 3.5E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 Gene3D G3DSA:1.25.40.10 195 256 1.1E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 Gene3D G3DSA:1.25.40.10 130 148 1.1E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 Gene3D G3DSA:1.25.40.10 257 335 1.6E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 Pfam PF13560 Helix-turn-helix domain 10 67 1.3E-8 T 06-07-2017 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 SUPERFAMILY SSF47413 5 68 5.07E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS15230 58bb8f05a8a51caf77f2c562e14eea15 447 Gene3D G3DSA:1.25.40.10 336 427 4.5E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15320 bc2c5186d0b69f65bc826439ef22db13 161 Pfam PF07179 SseB protein N-terminal domain 46 148 2.2E-8 T 06-07-2017 IPR009839 SseB protein N-terminal domain LK06_RS13255 2c6e1dbf2a185776a4c4e244bf976e5c 145 Gene3D G3DSA:1.10.1660.10 7 121 9.0E-32 T 06-07-2017 LK06_RS13255 2c6e1dbf2a185776a4c4e244bf976e5c 145 SMART SM00422 6 76 2.3E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS13255 2c6e1dbf2a185776a4c4e244bf976e5c 145 ProSitePatterns PS00552 MerR-type HTH domain signature. 9 31 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS13255 2c6e1dbf2a185776a4c4e244bf976e5c 145 Pfam PF13411 MerR HTH family regulatory protein 7 73 8.3E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS13255 2c6e1dbf2a185776a4c4e244bf976e5c 145 SUPERFAMILY SSF46955 7 121 8.06E-29 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS13255 2c6e1dbf2a185776a4c4e244bf976e5c 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 8.7E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS13255 2c6e1dbf2a185776a4c4e244bf976e5c 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 8.7E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS31775 02e5f19649e429e3691dcb5516153e60 541 Gene3D G3DSA:2.30.38.10 356 430 6.9E-19 T 06-07-2017 LK06_RS31775 02e5f19649e429e3691dcb5516153e60 541 Gene3D G3DSA:3.40.50.980 184 345 7.4E-15 T 06-07-2017 LK06_RS31775 02e5f19649e429e3691dcb5516153e60 541 SUPERFAMILY SSF56801 22 536 1.31E-81 T 06-07-2017 LK06_RS31775 02e5f19649e429e3691dcb5516153e60 541 Pfam PF00501 AMP-binding enzyme 33 434 1.0E-51 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS31775 02e5f19649e429e3691dcb5516153e60 541 Gene3D G3DSA:3.30.300.30 449 534 5.4E-6 T 06-07-2017 LK06_RS31775 02e5f19649e429e3691dcb5516153e60 541 Gene3D G3DSA:3.40.50.980 33 183 9.7E-18 T 06-07-2017 LK06_RS31775 02e5f19649e429e3691dcb5516153e60 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS29375 d97eb3d0c88aff28930aa6bc14f1fda4 531 SUPERFAMILY SSF103473 121 508 7.59E-39 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS29375 d97eb3d0c88aff28930aa6bc14f1fda4 531 Gene3D G3DSA:1.20.1250.20 339 505 2.0E-9 T 06-07-2017 LK06_RS29375 d97eb3d0c88aff28930aa6bc14f1fda4 531 Gene3D G3DSA:1.20.1250.20 114 312 8.6E-16 T 06-07-2017 LK06_RS29375 d97eb3d0c88aff28930aa6bc14f1fda4 531 Pfam PF07690 Major Facilitator Superfamily 129 467 5.2E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 Gene3D G3DSA:1.10.730.10 645 823 4.6E-49 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 SUPERFAMILY SSF47323 655 893 1.87E-49 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 SUPERFAMILY SSF52374 394 648 2.7E-122 T 06-07-2017 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 SUPERFAMILY SSF52374 9 202 2.7E-122 T 06-07-2017 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 SUPERFAMILY SSF50677 205 394 6.17E-47 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 Pfam PF08264 Anticodon-binding domain of tRNA 687 832 1.2E-31 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 9 838 1.6E-272 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 Gene3D G3DSA:3.40.50.620 398 635 4.0E-137 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 Gene3D G3DSA:3.40.50.620 9 198 4.0E-137 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 22 628 1.7E-167 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 7 1045 13.908 T 06-07-2017 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 Gene3D G3DSA:3.90.740.10 229 397 8.2E-54 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 2.6E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 519 532 2.6E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 392 407 2.6E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 45 56 2.6E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LK06_RS07260 52f6f1cfedfd9bee66c71be46d235416 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 559 568 2.6E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LK06_RS03640 a35d71baeadcd0c913d60b3503e92bc7 312 Pfam PF00498 FHA domain 236 299 3.1E-19 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS03640 a35d71baeadcd0c913d60b3503e92bc7 312 SMART SM00240 234 285 8.4E-13 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS03640 a35d71baeadcd0c913d60b3503e92bc7 312 SUPERFAMILY SSF49879 197 306 6.89E-31 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS03640 a35d71baeadcd0c913d60b3503e92bc7 312 Pfam PF13240 zinc-ribbon domain 140 161 1.9E-8 T 06-07-2017 IPR026870 Zinc-ribbon domain LK06_RS03640 a35d71baeadcd0c913d60b3503e92bc7 312 Gene3D G3DSA:2.60.200.20 213 307 2.3E-29 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 Gene3D G3DSA:3.90.700.10 277 406 8.6E-19 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 46 65 1.1E-7 T 06-07-2017 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 415 437 1.1E-7 T 06-07-2017 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 46 647 0.0 T 06-07-2017 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 Gene3D G3DSA:1.20.58.100 485 602 4.7E-31 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 Pfam PF00890 FAD binding domain 46 451 2.4E-61 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 Pfam PF02910 Fumarate reductase flavoprotein C-term 513 647 5.1E-35 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 Gene3D G3DSA:3.50.50.60 37 276 3.6E-77 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 Gene3D G3DSA:3.50.50.60 408 460 3.6E-77 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 SUPERFAMILY SSF46977 504 647 2.09E-39 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 SUPERFAMILY SSF56425 271 413 3.74E-34 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 SUPERFAMILY SSF51905 416 467 2.42E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01590 0058cba22e6489e9c7d121825abada73 648 SUPERFAMILY SSF51905 44 287 2.42E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS15980 0ace785a3f1deddfe2d8cf23a735b97f 373 Gene3D G3DSA:3.40.630.30 186 346 8.1E-53 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS15980 0ace785a3f1deddfe2d8cf23a735b97f 373 Pfam PF02388 FemAB family 266 367 1.9E-16 T 06-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 LK06_RS15980 0ace785a3f1deddfe2d8cf23a735b97f 373 Pfam PF02388 FemAB family 8 249 3.5E-28 T 06-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 LK06_RS15980 0ace785a3f1deddfe2d8cf23a735b97f 373 SUPERFAMILY SSF55729 144 195 6.89E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS15980 0ace785a3f1deddfe2d8cf23a735b97f 373 SUPERFAMILY SSF55729 5 115 6.89E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS15980 0ace785a3f1deddfe2d8cf23a735b97f 373 Gene3D G3DSA:3.40.630.30 149 185 4.3E-53 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS15980 0ace785a3f1deddfe2d8cf23a735b97f 373 Gene3D G3DSA:3.40.630.30 1 117 4.3E-53 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS15980 0ace785a3f1deddfe2d8cf23a735b97f 373 SUPERFAMILY SSF55729 184 366 2.07E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS00190 afe158687c17c513f354d16cfb6109d9 225 PIRSF PIRSF036990 6 224 2.8E-65 T 06-07-2017 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON LK06_RS00190 afe158687c17c513f354d16cfb6109d9 225 Pfam PF04972 BON domain 147 207 2.6E-14 T 06-07-2017 IPR007055 BON domain LK06_RS00190 afe158687c17c513f354d16cfb6109d9 225 Pfam PF00571 CBS domain 89 143 5.3E-14 T 06-07-2017 IPR000644 CBS domain LK06_RS00190 afe158687c17c513f354d16cfb6109d9 225 Pfam PF00571 CBS domain 8 60 9.4E-10 T 06-07-2017 IPR000644 CBS domain LK06_RS00190 afe158687c17c513f354d16cfb6109d9 225 SMART SM00116 15 63 1.2E-4 T 06-07-2017 IPR000644 CBS domain LK06_RS00190 afe158687c17c513f354d16cfb6109d9 225 SMART SM00116 96 144 2.3E-10 T 06-07-2017 IPR000644 CBS domain LK06_RS00190 afe158687c17c513f354d16cfb6109d9 225 Gene3D G3DSA:3.20.20.70 7 146 4.7E-30 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS00190 afe158687c17c513f354d16cfb6109d9 225 SUPERFAMILY SSF54631 5 146 2.27E-31 T 06-07-2017 LK06_RS20975 10fdaae9b243dc932d64ad29504a5933 166 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site LK06_RS20975 10fdaae9b243dc932d64ad29504a5933 166 SUPERFAMILY SSF46785 40 148 3.24E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20975 10fdaae9b243dc932d64ad29504a5933 166 Gene3D G3DSA:1.10.10.10 39 148 8.9E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20975 10fdaae9b243dc932d64ad29504a5933 166 Pfam PF01047 MarR family 44 99 6.6E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS20975 10fdaae9b243dc932d64ad29504a5933 166 SMART SM00347 36 134 8.7E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS20975 10fdaae9b243dc932d64ad29504a5933 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 7.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS20975 10fdaae9b243dc932d64ad29504a5933 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 7.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS20975 10fdaae9b243dc932d64ad29504a5933 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 7.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS20975 10fdaae9b243dc932d64ad29504a5933 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 7.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS10680 cebe8187dd891186726fefad5c33db0d 326 PIRSF PIRSF036979 14 316 5.7E-109 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 LK06_RS10680 cebe8187dd891186726fefad5c33db0d 326 SUPERFAMILY SSF52768 17 312 6.12E-99 T 06-07-2017 LK06_RS10680 cebe8187dd891186726fefad5c33db0d 326 Pfam PF00491 Arginase family 37 308 1.5E-90 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 LK06_RS10680 cebe8187dd891186726fefad5c33db0d 326 PRINTS PR00116 Arginase signature 124 139 1.6E-14 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 LK06_RS10680 cebe8187dd891186726fefad5c33db0d 326 PRINTS PR00116 Arginase signature 237 266 1.6E-14 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 LK06_RS10680 cebe8187dd891186726fefad5c33db0d 326 TIGRFAM TIGR01230 agmatinase: agmatinase 36 309 1.9E-69 T 06-07-2017 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 LK06_RS10680 cebe8187dd891186726fefad5c33db0d 326 ProSitePatterns PS01053 Arginase family signature. 240 261 - T 06-07-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 LK06_RS10680 cebe8187dd891186726fefad5c33db0d 326 Gene3D G3DSA:3.40.800.10 12 314 2.3E-117 T 06-07-2017 IPR023696 Ureohydrolase domain LK06_RS27545 f7d9e2701593f303b66f8bcafd54cf9f 376 Hamap MF_00813 Probable allantoicase [alc]. 27 360 50.585 T 06-07-2017 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 LK06_RS27545 f7d9e2701593f303b66f8bcafd54cf9f 376 Gene3D G3DSA:2.60.120.260 217 361 2.5E-40 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS27545 f7d9e2701593f303b66f8bcafd54cf9f 376 Gene3D G3DSA:2.60.120.260 32 210 4.5E-59 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS27545 f7d9e2701593f303b66f8bcafd54cf9f 376 PIRSF PIRSF016516 25 361 9.1E-92 T 06-07-2017 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 LK06_RS27545 f7d9e2701593f303b66f8bcafd54cf9f 376 Pfam PF03561 Allantoicase repeat 47 206 1.9E-45 T 06-07-2017 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 LK06_RS27545 f7d9e2701593f303b66f8bcafd54cf9f 376 Pfam PF03561 Allantoicase repeat 229 357 6.6E-34 T 06-07-2017 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 LK06_RS27545 f7d9e2701593f303b66f8bcafd54cf9f 376 SUPERFAMILY SSF49785 214 359 1.62E-42 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS27545 f7d9e2701593f303b66f8bcafd54cf9f 376 TIGRFAM TIGR02961 allantoicase: allantoicase 38 357 5.9E-124 T 06-07-2017 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 LK06_RS27545 f7d9e2701593f303b66f8bcafd54cf9f 376 SUPERFAMILY SSF49785 30 210 1.7E-54 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS31100 bea89cf1cc9abdd2c64e46e8721f4675 327 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 308 9.9E-116 T 06-07-2017 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family LK06_RS31100 bea89cf1cc9abdd2c64e46e8721f4675 327 SUPERFAMILY SSF56059 127 308 1.23E-22 T 06-07-2017 LK06_RS18400 8fa72172c6441e7a870d5ec646f1934f 357 SUPERFAMILY SSF55729 190 335 6.78E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS18400 8fa72172c6441e7a870d5ec646f1934f 357 Pfam PF13302 Acetyltransferase (GNAT) domain 228 331 1.3E-20 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS18400 8fa72172c6441e7a870d5ec646f1934f 357 Gene3D G3DSA:3.40.630.30 185 347 1.8E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS25260 cb1669d89a91a227f29c986749830ff9 646 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 17 188 1.8E-16 T 06-07-2017 IPR032856 Putative glycogen debranching enzyme, N-terminal LK06_RS25260 cb1669d89a91a227f29c986749830ff9 646 SUPERFAMILY SSF48208 218 631 2.72E-24 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS03990 9b1d69b8e91c12e9003eeb29bc04df68 157 SUPERFAMILY SSF46785 86 140 2.02E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03990 9b1d69b8e91c12e9003eeb29bc04df68 157 Gene3D G3DSA:1.10.10.10 81 130 5.5E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03990 9b1d69b8e91c12e9003eeb29bc04df68 157 Pfam PF05331 Protein of unknown function (DUF742) 41 156 1.2E-25 T 06-07-2017 IPR007995 Protein of unknown function DUF742 LK06_RS24805 1c8d9316f8ccf77315f6f019ecd39edf 446 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 56 446 1.8E-82 T 06-07-2017 IPR021368 Type VII secretion system protein EccE LK06_RS24805 1c8d9316f8ccf77315f6f019ecd39edf 446 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 240 348 4.6E-28 T 06-07-2017 IPR021368 Type VII secretion system protein EccE LK06_RS17790 0b1c69fa215e32d5162e019a33b03628 270 SUPERFAMILY SSF53335 15 188 1.99E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS17790 0b1c69fa215e32d5162e019a33b03628 270 Gene3D G3DSA:3.40.50.150 60 142 3.4E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS02635 98f38864e41009e253526f11397f5098 299 SUPERFAMILY SSF53474 36 130 5.33E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02635 98f38864e41009e253526f11397f5098 299 SUPERFAMILY SSF53474 162 213 5.33E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02635 98f38864e41009e253526f11397f5098 299 Gene3D G3DSA:3.40.50.1820 18 127 3.3E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS15170 40f81d1dcb02d8d5d99ad5caca74d7a0 678 Pfam PF01145 SPFH domain / Band 7 family 29 215 5.7E-8 T 06-07-2017 IPR001107 Band 7 domain LK06_RS15170 40f81d1dcb02d8d5d99ad5caca74d7a0 678 SUPERFAMILY SSF117892 53 201 1.83E-10 T 06-07-2017 IPR001107 Band 7 domain LK06_RS00975 98306be2d53414db8d4209689560c79a 368 Pfam PF13478 XdhC Rossmann domain 201 343 2.2E-42 T 06-07-2017 IPR027051 XdhC Rossmann domain LK06_RS00975 98306be2d53414db8d4209689560c79a 368 Pfam PF02625 XdhC and CoxI family 11 78 8.5E-19 T 06-07-2017 IPR003777 XdhC- CoxI LK06_RS00975 98306be2d53414db8d4209689560c79a 368 Pfam PF02625 XdhC and CoxI family 118 178 6.3E-14 T 06-07-2017 IPR003777 XdhC- CoxI LK06_RS25875 e4fa88949a04ae7476589a17053cfc91 436 Pfam PF08421 Putative zinc binding domain 4 65 8.3E-24 T 06-07-2017 IPR013630 Methyltransferase putative zinc binding domain LK06_RS25875 e4fa88949a04ae7476589a17053cfc91 436 Pfam PF08484 C-methyltransferase C-terminal domain 290 427 8.9E-57 T 06-07-2017 IPR013691 C-methyltransferase LK06_RS25875 e4fa88949a04ae7476589a17053cfc91 436 SUPERFAMILY SSF53335 61 249 1.49E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25875 e4fa88949a04ae7476589a17053cfc91 436 Gene3D G3DSA:3.40.50.150 87 255 3.5E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25875 e4fa88949a04ae7476589a17053cfc91 436 Pfam PF13489 Methyltransferase domain 81 238 6.9E-14 T 06-07-2017 LK06_RS05805 c54806f665d8eb969c08fef8b4a224d5 607 Gene3D G3DSA:1.25.40.10 540 585 1.4E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05805 c54806f665d8eb969c08fef8b4a224d5 607 Gene3D G3DSA:1.25.40.10 408 471 1.4E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05805 c54806f665d8eb969c08fef8b4a224d5 607 Pfam PF14559 Tetratricopeptide repeat 524 585 9.8E-6 T 06-07-2017 LK06_RS05805 c54806f665d8eb969c08fef8b4a224d5 607 SUPERFAMILY SSF48452 422 475 2.2E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05805 c54806f665d8eb969c08fef8b4a224d5 607 SUPERFAMILY SSF48452 512 581 2.2E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 Gene3D G3DSA:2.60.40.1180 481 559 3.8E-14 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 Gene3D G3DSA:3.20.20.80 198 427 1.7E-112 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 Gene3D G3DSA:3.20.20.80 460 474 1.7E-112 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 Gene3D G3DSA:3.20.20.80 25 122 1.7E-112 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 SUPERFAMILY SSF51445 34 481 2.58E-136 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 SMART SM00642 31 433 2.5E-122 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 558 1.9E-26 T 06-07-2017 IPR032091 Maltogenic Amylase, C-terminal LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 Pfam PF00128 Alpha amylase, catalytic domain 46 402 3.2E-79 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 561 1.7E-302 T 06-07-2017 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 Gene3D G3DSA:3.90.400.10 123 190 1.6E-24 T 06-07-2017 LK06_RS23630 b6904ed8bdc6a2fcd09f6381604458c3 566 SUPERFAMILY SSF51011 485 561 4.58E-16 T 06-07-2017 LK06_RS04385 75e71e43433cdb45722c865ad22d2f02 324 Gene3D G3DSA:3.60.15.10 78 275 8.2E-6 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS04385 75e71e43433cdb45722c865ad22d2f02 324 Gene3D G3DSA:3.60.15.10 2 37 8.2E-6 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS04385 75e71e43433cdb45722c865ad22d2f02 324 SUPERFAMILY SSF56281 90 311 3.18E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS26335 836538ddb5d5e82ec83d4f239b456c95 373 Gene3D G3DSA:3.30.9.10 219 307 1.2E-11 T 06-07-2017 LK06_RS26335 836538ddb5d5e82ec83d4f239b456c95 373 Gene3D G3DSA:3.30.9.10 90 142 1.2E-11 T 06-07-2017 LK06_RS26335 836538ddb5d5e82ec83d4f239b456c95 373 SUPERFAMILY SSF51905 8 219 8.8E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26335 836538ddb5d5e82ec83d4f239b456c95 373 SUPERFAMILY SSF51905 308 365 8.8E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26335 836538ddb5d5e82ec83d4f239b456c95 373 Gene3D G3DSA:3.50.50.60 308 364 1.5E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26335 836538ddb5d5e82ec83d4f239b456c95 373 Gene3D G3DSA:3.50.50.60 4 84 1.5E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26335 836538ddb5d5e82ec83d4f239b456c95 373 Gene3D G3DSA:3.50.50.60 143 218 1.5E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26335 836538ddb5d5e82ec83d4f239b456c95 373 Pfam PF01266 FAD dependent oxidoreductase 9 347 2.7E-37 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS12560 9d56bcfa097b607d78b0d68afc29c48e 558 SMART SM00507 469 530 9.6E-5 T 06-07-2017 IPR003615 HNH nuclease LK06_RS12560 9d56bcfa097b607d78b0d68afc29c48e 558 Pfam PF01844 HNH endonuclease 498 533 1.8E-7 T 06-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 LK06_RS28665 3d063d991a7825c888716e34fa9bef02 255 Gene3D G3DSA:3.90.226.10 5 240 3.5E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS28665 3d063d991a7825c888716e34fa9bef02 255 SUPERFAMILY SSF52096 5 244 2.16E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS28665 3d063d991a7825c888716e34fa9bef02 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 244 4.0E-43 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS27840 629729db36f56238034a1064f25c667b 280 SUPERFAMILY SSF56317 3 277 9.81E-80 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS27840 629729db36f56238034a1064f25c667b 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 261 3.8E-67 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS27840 629729db36f56238034a1064f25c667b 280 Gene3D G3DSA:3.60.110.10 4 278 2.9E-87 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS25590 ad5cf82ef078db0d0b1dec9711644dc8 362 Gene3D G3DSA:1.10.443.10 157 347 1.6E-38 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS25590 ad5cf82ef078db0d0b1dec9711644dc8 362 SUPERFAMILY SSF56349 54 345 9.42E-56 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS25590 ad5cf82ef078db0d0b1dec9711644dc8 362 Gene3D G3DSA:1.10.150.130 54 150 3.1E-13 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS25590 ad5cf82ef078db0d0b1dec9711644dc8 362 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 54 107 1.8E-5 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS25590 ad5cf82ef078db0d0b1dec9711644dc8 362 Pfam PF00589 Phage integrase family 157 340 1.3E-25 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS19045 4e4c6e8f4698bcb5b3b701323dcd399a 761 Gene3D G3DSA:3.40.710.10 409 642 1.6E-51 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS19045 4e4c6e8f4698bcb5b3b701323dcd399a 761 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 433 622 5.9E-33 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 LK06_RS19045 4e4c6e8f4698bcb5b3b701323dcd399a 761 SUPERFAMILY SSF56601 364 622 5.42E-41 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS19045 4e4c6e8f4698bcb5b3b701323dcd399a 761 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 439 450 4.1E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LK06_RS19045 4e4c6e8f4698bcb5b3b701323dcd399a 761 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 523 536 4.1E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LK06_RS19045 4e4c6e8f4698bcb5b3b701323dcd399a 761 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 496 513 4.1E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LK06_RS09535 7a4a97f6c735fe9635c9149a88a2ad7f 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.95 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS09535 7a4a97f6c735fe9635c9149a88a2ad7f 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 87 4.0E-16 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS09535 7a4a97f6c735fe9635c9149a88a2ad7f 88 Gene3D G3DSA:1.20.58.110 2 86 5.0E-30 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS09535 7a4a97f6c735fe9635c9149a88a2ad7f 88 Pfam PF01649 Ribosomal protein S20 2 83 2.2E-28 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS09535 7a4a97f6c735fe9635c9149a88a2ad7f 88 SUPERFAMILY SSF46992 3 86 1.31E-28 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS09535 7a4a97f6c735fe9635c9149a88a2ad7f 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 85 9.0E-23 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24545 89aca2049b0f01beca67c66c2e0a4db8 265 Pfam PF07398 MDMPI C-terminal domain 152 256 7.8E-11 T 06-07-2017 IPR010872 MDMPI C-terminal LK06_RS24545 89aca2049b0f01beca67c66c2e0a4db8 265 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 139 8.2E-19 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 LK06_RS24545 89aca2049b0f01beca67c66c2e0a4db8 265 SUPERFAMILY SSF109854 4 146 8.01E-8 T 06-07-2017 LK06_RS24545 89aca2049b0f01beca67c66c2e0a4db8 265 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 238 5.7E-22 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type LK06_RS25730 ab80eca196259697cc777d83338d7c25 292 Pfam PF13560 Helix-turn-helix domain 36 91 3.1E-13 T 06-07-2017 LK06_RS25730 ab80eca196259697cc777d83338d7c25 292 SMART SM00530 39 94 3.1E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS25730 ab80eca196259697cc777d83338d7c25 292 SUPERFAMILY SSF47413 35 87 2.57E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS25730 ab80eca196259697cc777d83338d7c25 292 Gene3D G3DSA:1.10.260.40 36 87 1.3E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS08785 35d8b24d82b605ee3bfa7014dda67469 152 PIRSF PIRSF000239 1 152 3.1E-31 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LK06_RS08785 35d8b24d82b605ee3bfa7014dda67469 152 SUPERFAMILY SSF52833 1 152 4.4E-51 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS08785 35d8b24d82b605ee3bfa7014dda67469 152 Pfam PF00578 AhpC/TSA family 5 130 9.9E-41 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LK06_RS08785 35d8b24d82b605ee3bfa7014dda67469 152 Gene3D G3DSA:3.40.30.10 2 152 5.4E-51 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS15290 168eeafe042d709429fc13f329382995 538 Hamap MF_01228 Methionine--tRNA ligase [metG]. 10 526 46.435 T 06-07-2017 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LK06_RS15290 168eeafe042d709429fc13f329382995 538 Gene3D G3DSA:1.10.730.10 353 532 1.5E-49 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS15290 168eeafe042d709429fc13f329382995 538 Gene3D G3DSA:3.40.50.620 11 123 1.1E-67 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS15290 168eeafe042d709429fc13f329382995 538 Gene3D G3DSA:3.40.50.620 242 351 1.1E-67 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS15290 168eeafe042d709429fc13f329382995 538 Gene3D G3DSA:2.170.220.10 126 241 1.3E-44 T 06-07-2017 LK06_RS15290 168eeafe042d709429fc13f329382995 538 Pfam PF08264 Anticodon-binding domain of tRNA 404 498 1.3E-6 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 LK06_RS15290 168eeafe042d709429fc13f329382995 538 SUPERFAMILY SSF52374 11 361 1.94E-105 T 06-07-2017 LK06_RS15290 168eeafe042d709429fc13f329382995 538 SUPERFAMILY SSF47323 365 532 7.48E-35 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS15290 168eeafe042d709429fc13f329382995 538 Pfam PF09334 tRNA synthetases class I (M) 14 376 5.2E-105 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS15290 168eeafe042d709429fc13f329382995 538 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 14 498 2.5E-150 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LK06_RS15290 168eeafe042d709429fc13f329382995 538 PRINTS PR01041 Methionyl-tRNA synthetase signature 272 287 5.2E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LK06_RS15290 168eeafe042d709429fc13f329382995 538 PRINTS PR01041 Methionyl-tRNA synthetase signature 240 251 5.2E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LK06_RS15290 168eeafe042d709429fc13f329382995 538 PRINTS PR01041 Methionyl-tRNA synthetase signature 364 375 5.2E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LK06_RS15290 168eeafe042d709429fc13f329382995 538 PRINTS PR01041 Methionyl-tRNA synthetase signature 48 62 5.2E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LK06_RS15290 168eeafe042d709429fc13f329382995 538 PRINTS PR01041 Methionyl-tRNA synthetase signature 16 29 5.2E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LK06_RS15290 168eeafe042d709429fc13f329382995 538 PRINTS PR01041 Methionyl-tRNA synthetase signature 97 108 5.2E-32 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LK06_RS00395 7afa44603e9c277ba59a14887c78b413 507 PIRSF PIRSF012702 8 492 1.2E-141 T 06-07-2017 IPR009197 Microcystin LR degradation protein MlrC LK06_RS00395 7afa44603e9c277ba59a14887c78b413 507 Pfam PF07364 Metallopeptidase family M81 13 294 2.7E-103 T 06-07-2017 IPR015995 Microcystin LR degradation protein MlrC, N-terminal LK06_RS00395 7afa44603e9c277ba59a14887c78b413 507 Pfam PF07171 MlrC C-terminus 303 473 8.9E-57 T 06-07-2017 IPR010799 Microcystin LR degradation protein MlrC, C-terminal LK06_RS00880 e427f97640b2a84e114df1f4b1b768a8 305 Pfam PF01380 SIS domain 148 275 1.2E-7 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 LK06_RS00880 e427f97640b2a84e114df1f4b1b768a8 305 Pfam PF01418 Helix-turn-helix domain, rpiR family 40 97 6.3E-13 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 LK06_RS00880 e427f97640b2a84e114df1f4b1b768a8 305 SUPERFAMILY SSF53697 115 297 1.11E-12 T 06-07-2017 LK06_RS00880 e427f97640b2a84e114df1f4b1b768a8 305 Gene3D G3DSA:3.40.50.10490 88 264 8.5E-10 T 06-07-2017 LK06_RS00880 e427f97640b2a84e114df1f4b1b768a8 305 SUPERFAMILY SSF46689 38 98 2.87E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS00880 e427f97640b2a84e114df1f4b1b768a8 305 Gene3D G3DSA:1.10.10.10 38 87 3.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00005 46cedcb730a0daa3dcfaedc4cc388659 265 SUPERFAMILY SSF52518 60 241 2.5E-37 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS00005 46cedcb730a0daa3dcfaedc4cc388659 265 Gene3D G3DSA:3.40.50.970 58 242 1.3E-39 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS00005 46cedcb730a0daa3dcfaedc4cc388659 265 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 82 230 2.0E-24 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LK06_RS04185 a52a344646b9f47f884a29cce325cd2d 541 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 227 535 1.5E-46 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like LK06_RS04185 a52a344646b9f47f884a29cce325cd2d 541 Gene3D G3DSA:3.30.160.60 508 540 7.1E-6 T 06-07-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 LK06_RS04185 a52a344646b9f47f884a29cce325cd2d 541 Pfam PF02618 YceG-like family 233 532 2.7E-62 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 559 571 - T 06-07-2017 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 132 143 - T 06-07-2017 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 SUPERFAMILY SSF51621 17 914 5.02E-272 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 Pfam PF00311 Phosphoenolpyruvate carboxylase 127 914 6.0E-285 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 Gene3D G3DSA:1.20.1440.90 273 395 1.3E-23 T 06-07-2017 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 557 577 2.5E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 131 144 2.5E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 393 413 2.5E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 599 628 2.5E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 736 762 2.5E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 238 253 2.5E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 180 196 2.5E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS19810 54b3672fe5a9585a4732b3db2a6e1807 914 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 8 914 18.244 T 06-07-2017 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LK06_RS07640 8c3dfa93f89bc4d5c5325a763c478698 420 Pfam PF03734 L,D-transpeptidase catalytic domain 248 368 8.6E-13 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 LK06_RS07640 8c3dfa93f89bc4d5c5325a763c478698 420 Gene3D G3DSA:2.40.440.10 247 370 6.1E-17 T 06-07-2017 LK06_RS07640 8c3dfa93f89bc4d5c5325a763c478698 420 SUPERFAMILY SSF141523 243 368 2.09E-27 T 06-07-2017 LK06_RS28285 b76b61201e67fcd0221c55c90352ba76 552 Pfam PF05257 CHAP domain 67 153 2.4E-13 T 06-07-2017 IPR007921 CHAP domain LK06_RS28285 b76b61201e67fcd0221c55c90352ba76 552 SUPERFAMILY SSF54001 62 158 4.71E-12 T 06-07-2017 LK06_RS11595 af49437dec153139f8077fb710b03148 368 Gene3D G3DSA:1.20.58.410 4 115 3.1E-34 T 06-07-2017 LK06_RS11595 af49437dec153139f8077fb710b03148 368 Pfam PF00472 RF-1 domain 228 336 1.3E-38 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LK06_RS11595 af49437dec153139f8077fb710b03148 368 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 363 2.7E-154 T 06-07-2017 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 LK06_RS11595 af49437dec153139f8077fb710b03148 368 Gene3D G3DSA:3.30.160.20 227 305 5.7E-36 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain LK06_RS11595 af49437dec153139f8077fb710b03148 368 Pfam PF03462 PCRF domain 30 219 3.7E-56 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 LK06_RS11595 af49437dec153139f8077fb710b03148 368 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 37.991 T 06-07-2017 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 LK06_RS11595 af49437dec153139f8077fb710b03148 368 SMART SM00937 84 194 3.5E-44 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 LK06_RS11595 af49437dec153139f8077fb710b03148 368 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LK06_RS11595 af49437dec153139f8077fb710b03148 368 SUPERFAMILY SSF75620 29 366 5.1E-122 T 06-07-2017 LK06_RS13465 94bbc4b42b8dce8a8f5061558aea9fba 32 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 2 30 3.0E-9 T 06-07-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS13465 94bbc4b42b8dce8a8f5061558aea9fba 32 SMART SM01155 1 32 3.8E-5 T 06-07-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS29250 1747b7b67d66ccdb7feb0b51d0914fd6 133 Pfam PF01047 MarR family 24 80 3.6E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29250 1747b7b67d66ccdb7feb0b51d0914fd6 133 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 92 3.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29250 1747b7b67d66ccdb7feb0b51d0914fd6 133 PRINTS PR00598 Bacterial regulatory protein MarR family signature 40 56 3.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29250 1747b7b67d66ccdb7feb0b51d0914fd6 133 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 72 3.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29250 1747b7b67d66ccdb7feb0b51d0914fd6 133 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 125 3.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29250 1747b7b67d66ccdb7feb0b51d0914fd6 133 SMART SM00347 17 115 4.3E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29250 1747b7b67d66ccdb7feb0b51d0914fd6 133 ProSitePatterns PS01117 MarR-type HTH domain signature. 55 89 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site LK06_RS29250 1747b7b67d66ccdb7feb0b51d0914fd6 133 SUPERFAMILY SSF46785 10 125 2.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29250 1747b7b67d66ccdb7feb0b51d0914fd6 133 Gene3D G3DSA:1.10.10.10 10 126 1.6E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15325 07b660e40c3b97b5c73d6792ad800244 608 Gene3D G3DSA:2.40.110.10 161 272 1.3E-25 T 06-07-2017 LK06_RS15325 07b660e40c3b97b5c73d6792ad800244 608 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 3.2E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS15325 07b660e40c3b97b5c73d6792ad800244 608 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 471 604 8.9E-27 T 06-07-2017 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain LK06_RS15325 07b660e40c3b97b5c73d6792ad800244 608 Gene3D G3DSA:1.20.140.10 273 466 1.8E-41 T 06-07-2017 LK06_RS15325 07b660e40c3b97b5c73d6792ad800244 608 SUPERFAMILY SSF47203 290 469 4.51E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS15325 07b660e40c3b97b5c73d6792ad800244 608 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 452 7.8E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS15325 07b660e40c3b97b5c73d6792ad800244 608 SUPERFAMILY SSF56645 37 282 2.75E-40 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS15325 07b660e40c3b97b5c73d6792ad800244 608 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 8.6E-11 T 06-07-2017 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria LK06_RS02525 e3462402af0bd406fe96410acc8a7e81 265 Gene3D G3DSA:1.20.120.450 4 122 4.5E-8 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase LK06_RS02525 e3462402af0bd406fe96410acc8a7e81 265 Pfam PF08608 Wyosine base formation 184 232 7.0E-5 T 06-07-2017 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 LK06_RS02525 e3462402af0bd406fe96410acc8a7e81 265 SUPERFAMILY SSF109854 2 152 4.94E-24 T 06-07-2017 LK06_RS02525 e3462402af0bd406fe96410acc8a7e81 265 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 147 7.8E-24 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 LK06_RS02525 e3462402af0bd406fe96410acc8a7e81 265 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 6 258 3.3E-90 T 06-07-2017 IPR017518 Conserved hypothetical protein CHP03084 LK06_RS02525 e3462402af0bd406fe96410acc8a7e81 265 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 225 7.0E-42 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type LK06_RS09855 46545dce88c101ba48eea99fb410f138 398 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 33 394 2.4E-104 T 06-07-2017 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 LK06_RS09855 46545dce88c101ba48eea99fb410f138 398 Pfam PF01098 Cell cycle protein 36 393 9.3E-91 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 LK06_RS09855 46545dce88c101ba48eea99fb410f138 398 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 352 376 - T 06-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 LK06_RS28680 ad3ff8a29baf0f3395d685361f6b35a0 313 SUPERFAMILY SSF161111 24 220 5.89E-55 T 06-07-2017 LK06_RS28680 ad3ff8a29baf0f3395d685361f6b35a0 313 Gene3D G3DSA:3.30.70.1350 223 301 5.4E-4 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain LK06_RS28680 ad3ff8a29baf0f3395d685361f6b35a0 313 SUPERFAMILY SSF160240 222 301 2.75E-12 T 06-07-2017 LK06_RS28680 ad3ff8a29baf0f3395d685361f6b35a0 313 Pfam PF01545 Cation efflux family 28 219 5.3E-48 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LK06_RS28680 ad3ff8a29baf0f3395d685361f6b35a0 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 27 302 4.6E-94 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LK06_RS28680 ad3ff8a29baf0f3395d685361f6b35a0 313 Gene3D G3DSA:1.20.1510.10 26 219 2.2E-60 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain LK06_RS07330 8266678fa9ebec1e10d052a6a1050c01 657 SUPERFAMILY SSF56519 102 292 2.22E-32 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 LK06_RS07330 8266678fa9ebec1e10d052a6a1050c01 657 SUPERFAMILY SSF56601 293 644 1.08E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS07330 8266678fa9ebec1e10d052a6a1050c01 657 Gene3D G3DSA:3.40.710.10 300 638 4.1E-88 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS07330 8266678fa9ebec1e10d052a6a1050c01 657 Pfam PF00905 Penicillin binding protein transpeptidase domain 318 633 2.2E-71 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS07330 8266678fa9ebec1e10d052a6a1050c01 657 Pfam PF03717 Penicillin-binding Protein dimerisation domain 105 271 6.1E-17 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 LK06_RS07330 8266678fa9ebec1e10d052a6a1050c01 657 Gene3D G3DSA:3.90.1310.10 211 299 1.6E-24 T 06-07-2017 LK06_RS28795 192d640c8a5893b67a2ba9142aae2ff4 261 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 180 1.1E-25 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS28795 192d640c8a5893b67a2ba9142aae2ff4 261 Gene3D G3DSA:3.40.50.1110 5 190 1.1E-37 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS28795 192d640c8a5893b67a2ba9142aae2ff4 261 SUPERFAMILY SSF52266 5 188 8.09E-35 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS10690 d8d7a74fbb39ab153b8134a2569816cc 262 Pfam PF15698 Phosphatase 12 261 3.4E-108 T 06-07-2017 IPR031423 Uncharacterised phosphatase SCO2771 LK06_RS05690 b6f8a184ddb31687a7ea92d89590442b 334 Pfam PF02616 Segregation and condensation protein ScpA 73 293 4.0E-50 T 06-07-2017 IPR003768 Segregation and condensation protein A LK06_RS16055 8f16b6f51173adc91dd6a5f5731555ae 160 Gene3D G3DSA:3.90.79.10 3 113 7.7E-19 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS16055 8f16b6f51173adc91dd6a5f5731555ae 160 SUPERFAMILY SSF55811 2 113 7.99E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS16055 8f16b6f51173adc91dd6a5f5731555ae 160 Pfam PF00293 NUDIX domain 9 113 4.0E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS13340 113267468b63201f7a5e64c457e0bba0 261 Pfam PF12079 Protein of unknown function (DUF3558) 3 117 1.8E-9 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 LK06_RS19830 6b3815c67faaa40d1e0a530c9128892f 326 Gene3D G3DSA:3.40.50.2020 9 166 1.6E-68 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS19830 6b3815c67faaa40d1e0a530c9128892f 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 13 128 6.9E-44 T 06-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 LK06_RS19830 6b3815c67faaa40d1e0a530c9128892f 326 SMART SM01400 12 128 9.5E-69 T 06-07-2017 LK06_RS19830 6b3815c67faaa40d1e0a530c9128892f 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 06-07-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 LK06_RS19830 6b3815c67faaa40d1e0a530c9128892f 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 324 6.2E-113 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 LK06_RS19830 6b3815c67faaa40d1e0a530c9128892f 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 215 323 1.5E-22 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 LK06_RS19830 6b3815c67faaa40d1e0a530c9128892f 326 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 324 46.811 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 LK06_RS19830 6b3815c67faaa40d1e0a530c9128892f 326 SUPERFAMILY SSF53271 77 315 6.66E-62 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS19830 6b3815c67faaa40d1e0a530c9128892f 326 Gene3D G3DSA:3.40.50.2020 167 290 1.4E-46 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS21290 774c9f8750f8e8ae79334f6a82bf2281 404 Pfam PF07730 Histidine kinase 170 237 4.1E-13 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS21290 774c9f8750f8e8ae79334f6a82bf2281 404 SUPERFAMILY SSF55874 285 392 4.06E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21290 774c9f8750f8e8ae79334f6a82bf2281 404 Gene3D G3DSA:3.30.565.10 299 391 1.8E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21290 774c9f8750f8e8ae79334f6a82bf2281 404 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 298 391 7.4E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21290 774c9f8750f8e8ae79334f6a82bf2281 404 SMART SM00387 294 393 9.0E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS20945 37aca03b83525bee77f4e1494363b630 425 Gene3D G3DSA:3.40.630.30 5 134 6.9E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS20945 37aca03b83525bee77f4e1494363b630 425 Gene3D G3DSA:3.40.50.300 157 344 1.4E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20945 37aca03b83525bee77f4e1494363b630 425 SMART SM00382 195 331 1.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS20945 37aca03b83525bee77f4e1494363b630 425 SUPERFAMILY SSF52540 157 409 3.22E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20945 37aca03b83525bee77f4e1494363b630 425 Pfam PF00583 Acetyltransferase (GNAT) family 53 107 2.3E-5 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS20945 37aca03b83525bee77f4e1494363b630 425 SUPERFAMILY SSF55729 1 137 1.83E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS20945 37aca03b83525bee77f4e1494363b630 425 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 199 327 8.6E-25 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS26830 232dfb5ee50314f60faedf8555bb21d2 187 SUPERFAMILY SSF50156 114 185 3.32E-11 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS26830 232dfb5ee50314f60faedf8555bb21d2 187 Gene3D G3DSA:2.30.42.10 103 184 1.4E-13 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS26830 232dfb5ee50314f60faedf8555bb21d2 187 SMART SM00228 102 173 0.0033 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS26830 232dfb5ee50314f60faedf8555bb21d2 187 Pfam PF13180 PDZ domain 103 172 2.8E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS25705 ca7ec432e5688f2264384268cf83cafe 340 Gene3D G3DSA:3.40.50.720 1 227 1.5E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25705 ca7ec432e5688f2264384268cf83cafe 340 SUPERFAMILY SSF51735 1 307 2.18E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20110 4bf01b86295c732eec8d0bebd6d7203d 274 Gene3D G3DSA:3.20.20.370 82 272 2.4E-24 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS20110 4bf01b86295c732eec8d0bebd6d7203d 274 SUPERFAMILY SSF88713 82 243 8.23E-27 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS20110 4bf01b86295c732eec8d0bebd6d7203d 274 Pfam PF01522 Polysaccharide deacetylase 88 205 3.6E-21 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS20665 5370acf3a2a24e5908bceb98c4019441 427 SUPERFAMILY SSF141523 273 395 4.32E-27 T 06-07-2017 LK06_RS20665 5370acf3a2a24e5908bceb98c4019441 427 Pfam PF03734 L,D-transpeptidase catalytic domain 273 394 1.5E-15 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 LK06_RS20665 5370acf3a2a24e5908bceb98c4019441 427 Gene3D G3DSA:2.40.440.10 272 395 2.4E-20 T 06-07-2017 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 354 363 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 Gene3D G3DSA:1.10.630.10 17 408 4.6E-113 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 SUPERFAMILY SSF48264 18 408 9.95E-86 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 PRINTS PR00359 B-class P450 signature 94 105 5.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 PRINTS PR00359 B-class P450 signature 286 297 5.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 PRINTS PR00359 B-class P450 signature 160 175 5.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 PRINTS PR00359 B-class P450 signature 143 159 5.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 PRINTS PR00359 B-class P450 signature 352 361 5.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 PRINTS PR00359 B-class P450 signature 205 227 5.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 PRINTS PR00359 B-class P450 signature 303 330 5.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 PRINTS PR00359 B-class P450 signature 331 346 5.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 PRINTS PR00359 B-class P450 signature 361 372 5.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS29440 a05a715696840a31c50cce62110b831f 410 Pfam PF00067 Cytochrome P450 53 376 2.1E-23 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS04570 601f13dd2f8b6355744982051ef8a014 1366 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 796 1001 3.3E-91 T 06-07-2017 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 LK06_RS04570 601f13dd2f8b6355744982051ef8a014 1366 Pfam PF02277 Phosphoribosyltransferase 1026 1363 2.1E-126 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS04570 601f13dd2f8b6355744982051ef8a014 1366 Gene3D G3DSA:3.40.109.10 800 1007 4.5E-51 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS04570 601f13dd2f8b6355744982051ef8a014 1366 SUPERFAMILY SSF55469 804 1009 9.03E-53 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS04570 601f13dd2f8b6355744982051ef8a014 1366 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1030 1363 2.3E-126 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS04570 601f13dd2f8b6355744982051ef8a014 1366 SUPERFAMILY SSF52733 1021 1364 1.96E-113 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS04570 601f13dd2f8b6355744982051ef8a014 1366 Gene3D G3DSA:3.40.50.10210 1090 1346 2.0E-113 T 06-07-2017 LK06_RS04570 601f13dd2f8b6355744982051ef8a014 1366 Gene3D G3DSA:1.10.1610.10 1018 1089 4.2E-28 T 06-07-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS04570 601f13dd2f8b6355744982051ef8a014 1366 Pfam PF00881 Nitroreductase family 808 975 2.2E-31 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 LK06_RS04570 601f13dd2f8b6355744982051ef8a014 1366 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1028 1365 35.093 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS21630 516863f3e0001e295a4678aaa3a68902 303 Gene3D G3DSA:3.90.1200.10 131 290 1.8E-7 T 06-07-2017 LK06_RS21630 516863f3e0001e295a4678aaa3a68902 303 SUPERFAMILY SSF56112 4 301 2.48E-21 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS21630 516863f3e0001e295a4678aaa3a68902 303 Pfam PF01636 Phosphotransferase enzyme family 52 236 8.4E-13 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS03490 16c9cc9d1880002eb7177d554a8e26ec 255 Pfam PF01909 Nucleotidyltransferase domain 15 68 2.9E-7 T 06-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 LK06_RS03490 16c9cc9d1880002eb7177d554a8e26ec 255 Gene3D G3DSA:3.30.460.10 7 102 2.1E-11 T 06-07-2017 LK06_RS03490 16c9cc9d1880002eb7177d554a8e26ec 255 SUPERFAMILY SSF81301 7 60 8.18E-9 T 06-07-2017 LK06_RS30900 762cd06599cdc6681334be3a76e1216c 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 76 99 9.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30900 762cd06599cdc6681334be3a76e1216c 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 68 9.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30900 762cd06599cdc6681334be3a76e1216c 242 Pfam PF00440 Bacterial regulatory proteins, tetR family 55 101 5.8E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30900 762cd06599cdc6681334be3a76e1216c 242 SUPERFAMILY SSF48498 127 230 2.84E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS30900 762cd06599cdc6681334be3a76e1216c 242 Gene3D G3DSA:1.10.357.10 41 234 3.9E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS30900 762cd06599cdc6681334be3a76e1216c 242 SUPERFAMILY SSF46689 41 122 5.82E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS04630 1496ec2daf25855a14fd79077ab8f095 507 Gene3D G3DSA:1.20.1250.20 273 428 3.8E-17 T 06-07-2017 LK06_RS04630 1496ec2daf25855a14fd79077ab8f095 507 Gene3D G3DSA:1.20.1250.20 475 502 3.8E-17 T 06-07-2017 LK06_RS04630 1496ec2daf25855a14fd79077ab8f095 507 Gene3D G3DSA:1.20.1250.20 23 202 2.8E-28 T 06-07-2017 LK06_RS04630 1496ec2daf25855a14fd79077ab8f095 507 Pfam PF07690 Major Facilitator Superfamily 26 417 3.1E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS04630 1496ec2daf25855a14fd79077ab8f095 507 SUPERFAMILY SSF103473 14 206 1.44E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS04630 1496ec2daf25855a14fd79077ab8f095 507 SUPERFAMILY SSF103473 474 501 1.44E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS04630 1496ec2daf25855a14fd79077ab8f095 507 SUPERFAMILY SSF103473 256 427 1.44E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS01480 7ad0706314173750e88fe37f28be3243 124 Pfam PF00085 Thioredoxin 4 101 2.6E-28 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 LK06_RS01480 7ad0706314173750e88fe37f28be3243 124 Gene3D G3DSA:3.40.30.10 2 102 4.8E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS01480 7ad0706314173750e88fe37f28be3243 124 PIRSF PIRSF000077 1 105 4.0E-29 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LK06_RS01480 7ad0706314173750e88fe37f28be3243 124 SUPERFAMILY SSF52833 3 103 2.65E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS01480 7ad0706314173750e88fe37f28be3243 124 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 LK06_RS01480 7ad0706314173750e88fe37f28be3243 124 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 103 3.6E-30 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LK06_RS01480 7ad0706314173750e88fe37f28be3243 124 PRINTS PR00421 Thioredoxin family signature 30 39 6.0E-8 T 06-07-2017 LK06_RS01480 7ad0706314173750e88fe37f28be3243 124 PRINTS PR00421 Thioredoxin family signature 22 30 6.0E-8 T 06-07-2017 LK06_RS01480 7ad0706314173750e88fe37f28be3243 124 PRINTS PR00421 Thioredoxin family signature 69 80 6.0E-8 T 06-07-2017 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 SMART SM00387 372 478 4.9E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 Pfam PF00512 His Kinase A (phospho-acceptor) domain 261 330 2.3E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 Gene3D G3DSA:1.10.287.130 250 317 1.3E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 475 2.3E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 Pfam PF00672 HAMP domain 184 254 6.6E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 SUPERFAMILY SSF55874 321 479 5.11E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 SUPERFAMILY SSF47384 243 330 1.12E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 475 6.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 6.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 6.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 456 6.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 SUPERFAMILY SSF158472 207 256 1.57E-6 T 06-07-2017 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 Gene3D G3DSA:3.30.565.10 318 479 3.5E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 SMART SM00304 204 259 1.1E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS17560 0bfd482f4fcfd1e53680b0c478cbf8e0 485 SMART SM00388 260 331 1.4E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LK06_RS19450 9ab6713dd55f501775187f0d2e5eb41e 737 Gene3D G3DSA:3.40.50.300 519 666 9.9E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19450 9ab6713dd55f501775187f0d2e5eb41e 737 Gene3D G3DSA:3.40.50.300 275 388 9.9E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19450 9ab6713dd55f501775187f0d2e5eb41e 737 SUPERFAMILY SSF52540 293 688 1.04E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17815 cc07734488153f593b219ec6c03af210 253 SUPERFAMILY SSF53254 6 227 4.5E-70 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS17815 cc07734488153f593b219ec6c03af210 253 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 251 5.5E-111 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 LK06_RS17815 cc07734488153f593b219ec6c03af210 253 SMART SM00855 7 193 3.6E-22 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS17815 cc07734488153f593b219ec6c03af210 253 Gene3D G3DSA:3.40.50.1240 5 253 1.0E-86 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS17815 cc07734488153f593b219ec6c03af210 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 132 6.7E-25 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS17815 cc07734488153f593b219ec6c03af210 253 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 234 42.008 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 LK06_RS17815 cc07734488153f593b219ec6c03af210 253 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 LK06_RS04085 ee120329fb8f2f9566fab9c22199fb87 90 Gene3D G3DSA:3.90.940.10 11 85 6.0E-33 T 06-07-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 LK06_RS04085 ee120329fb8f2f9566fab9c22199fb87 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 12 80 2.8E-21 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS04085 ee120329fb8f2f9566fab9c22199fb87 90 SUPERFAMILY SSF63562 11 86 7.32E-24 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 LK06_RS04085 ee120329fb8f2f9566fab9c22199fb87 90 SMART SM01409 18 82 3.1E-13 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 LK06_RS04085 ee120329fb8f2f9566fab9c22199fb87 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 11 83 14.523 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LK06_RS04085 ee120329fb8f2f9566fab9c22199fb87 90 Pfam PF01192 RNA polymerase Rpb6 18 80 1.2E-13 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 LK06_RS01300 e7c9dd1a7fa56242f444cb96a461d0ad 492 Gene3D G3DSA:1.10.1060.10 314 399 2.1E-11 T 06-07-2017 LK06_RS01300 e7c9dd1a7fa56242f444cb96a461d0ad 492 Gene3D G3DSA:3.40.50.10420 197 300 1.5E-46 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain LK06_RS01300 e7c9dd1a7fa56242f444cb96a461d0ad 492 Gene3D G3DSA:3.40.50.10420 66 129 1.5E-46 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain LK06_RS01300 e7c9dd1a7fa56242f444cb96a461d0ad 492 Pfam PF13183 4Fe-4S dicluster domain 315 384 2.9E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LK06_RS01300 e7c9dd1a7fa56242f444cb96a461d0ad 492 SUPERFAMILY SSF54862 296 399 9.63E-15 T 06-07-2017 LK06_RS01300 e7c9dd1a7fa56242f444cb96a461d0ad 492 SUPERFAMILY SSF100950 136 300 6.28E-36 T 06-07-2017 LK06_RS01300 e7c9dd1a7fa56242f444cb96a461d0ad 492 SUPERFAMILY SSF100950 66 90 6.28E-36 T 06-07-2017 LK06_RS01300 e7c9dd1a7fa56242f444cb96a461d0ad 492 Pfam PF11870 Domain of unknown function (DUF3390) 393 483 9.0E-15 T 06-07-2017 IPR024569 4Fe-4S binding protein, C-terminal LK06_RS01300 e7c9dd1a7fa56242f444cb96a461d0ad 492 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 318 329 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS01300 e7c9dd1a7fa56242f444cb96a461d0ad 492 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 73 299 3.2E-48 T 06-07-2017 IPR003741 LUD domain LK06_RS05560 5a1bd96d44a02eb9ebe3be1d7e5bd217 1168 Pfam PF02811 PHP domain 6 188 1.4E-13 T 06-07-2017 IPR004013 PHP domain GO:0003824 LK06_RS05560 5a1bd96d44a02eb9ebe3be1d7e5bd217 1168 SUPERFAMILY SSF89550 6 66 1.84E-5 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 LK06_RS05560 5a1bd96d44a02eb9ebe3be1d7e5bd217 1168 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 344 753 1.7E-126 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS05560 5a1bd96d44a02eb9ebe3be1d7e5bd217 1168 SMART SM00481 5 72 9.0E-18 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 LK06_RS05560 5a1bd96d44a02eb9ebe3be1d7e5bd217 1168 Pfam PF14579 Helix-hairpin-helix motif 831 920 7.9E-15 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS05560 5a1bd96d44a02eb9ebe3be1d7e5bd217 1168 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1008 8.8E-151 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS05560 5a1bd96d44a02eb9ebe3be1d7e5bd217 1168 Gene3D G3DSA:3.20.20.140 6 71 1.0E-6 T 06-07-2017 LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 1.4E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 SMART SM00344 1 108 1.5E-42 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.4E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.4E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.4E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 Gene3D G3DSA:3.30.70.920 54 133 3.0E-24 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 Pfam PF01037 Lrp/AsnC ligand binding domain 67 137 3.3E-16 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 SUPERFAMILY SSF54909 61 144 3.75E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 SUPERFAMILY SSF46785 1 60 4.97E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03865 c3c76920cd8b700833745e9e7b0a4928 146 Gene3D G3DSA:1.10.10.10 3 53 9.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03030 59d129b5dcabce7b2e354687483cfc71 393 SUPERFAMILY SSF53756 4 389 1.39E-65 T 06-07-2017 LK06_RS03030 59d129b5dcabce7b2e354687483cfc71 393 Gene3D G3DSA:3.40.50.2000 229 370 1.9E-28 T 06-07-2017 LK06_RS03030 59d129b5dcabce7b2e354687483cfc71 393 Gene3D G3DSA:3.40.50.2000 10 228 4.3E-17 T 06-07-2017 LK06_RS03030 59d129b5dcabce7b2e354687483cfc71 393 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 273 362 7.2E-13 T 06-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 LK06_RS11325 118d43616ad117cb39c0886b57030b01 319 Gene3D G3DSA:3.40.190.10 268 319 9.4E-51 T 06-07-2017 LK06_RS11325 118d43616ad117cb39c0886b57030b01 319 Gene3D G3DSA:3.40.190.10 44 151 9.4E-51 T 06-07-2017 LK06_RS11325 118d43616ad117cb39c0886b57030b01 319 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 46 314 2.4E-57 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 LK06_RS11325 118d43616ad117cb39c0886b57030b01 319 SUPERFAMILY SSF53850 47 318 1.63E-57 T 06-07-2017 LK06_RS11325 118d43616ad117cb39c0886b57030b01 319 Gene3D G3DSA:3.40.190.120 152 256 5.6E-34 T 06-07-2017 LK06_RS21540 a16234cba1f796988d6f67df688b2d79 277 SUPERFAMILY SSF47413 4 61 3.38E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS21540 a16234cba1f796988d6f67df688b2d79 277 Gene3D G3DSA:1.10.260.40 4 62 1.2E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS21540 a16234cba1f796988d6f67df688b2d79 277 Pfam PF13560 Helix-turn-helix domain 6 63 1.1E-15 T 06-07-2017 LK06_RS21540 a16234cba1f796988d6f67df688b2d79 277 SMART SM00530 9 64 1.4E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 Gene3D G3DSA:3.30.379.10 5 133 1.4E-25 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 Gene3D G3DSA:3.20.20.80 135 520 7.1E-136 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 SUPERFAMILY SSF55545 4 136 3.79E-20 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 137 484 2.8E-120 T 06-07-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 PIRSF PIRSF001093 72 527 4.3E-73 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 5 133 1.2E-17 T 06-07-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 282 300 6.2E-36 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 160 181 6.2E-36 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 448 464 6.2E-36 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 87 107 6.2E-36 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 231 248 6.2E-36 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 304 317 6.2E-36 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 466 483 6.2E-36 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 LK06_RS11410 28ea0ef89c2d5f78445cde77900a2566 541 SUPERFAMILY SSF51445 137 500 1.1E-115 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS30605 35481d206d5afc902082aaa901bd18f6 388 Gene3D G3DSA:3.40.47.10 196 220 3.1E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS30605 35481d206d5afc902082aaa901bd18f6 388 Gene3D G3DSA:3.40.47.10 14 118 3.1E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS30605 35481d206d5afc902082aaa901bd18f6 388 Gene3D G3DSA:3.40.47.10 264 359 1.8E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS30605 35481d206d5afc902082aaa901bd18f6 388 SUPERFAMILY SSF53901 5 122 1.39E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS30605 35481d206d5afc902082aaa901bd18f6 388 SUPERFAMILY SSF53901 198 378 1.39E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03200 6a872ffbf4bbb336e3e937917a190650 203 SUPERFAMILY SSF46689 7 83 1.44E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS03200 6a872ffbf4bbb336e3e937917a190650 203 SUPERFAMILY SSF48498 89 189 2.06E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS03200 6a872ffbf4bbb336e3e937917a190650 203 Gene3D G3DSA:1.10.357.10 2 191 4.7E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS03200 6a872ffbf4bbb336e3e937917a190650 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.8E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS06635 c16393649ac02ac93dac5fc107f16cdc 364 Gene3D G3DSA:3.40.50.10680 122 355 3.8E-43 T 06-07-2017 LK06_RS06635 c16393649ac02ac93dac5fc107f16cdc 364 SUPERFAMILY SSF142338 46 350 1.2E-83 T 06-07-2017 LK06_RS06635 c16393649ac02ac93dac5fc107f16cdc 364 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 49 353 8.9E-83 T 06-07-2017 IPR010119 Gluconeogenesis factor LK06_RS06635 c16393649ac02ac93dac5fc107f16cdc 364 Hamap MF_00973 Gluconeogenesis factor. 45 356 32.601 T 06-07-2017 IPR010119 Gluconeogenesis factor LK06_RS06635 c16393649ac02ac93dac5fc107f16cdc 364 Pfam PF01933 Uncharacterised protein family UPF0052 49 315 1.3E-70 T 06-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 LK06_RS13825 dfce1c4e087148842fd1979c9b658690 163 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.929 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 LK06_RS13825 dfce1c4e087148842fd1979c9b658690 163 Pfam PF00719 Inorganic pyrophosphatase 5 158 1.1E-51 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 LK06_RS13825 dfce1c4e087148842fd1979c9b658690 163 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 LK06_RS13825 dfce1c4e087148842fd1979c9b658690 163 SUPERFAMILY SSF50324 3 158 7.2E-58 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 LK06_RS13825 dfce1c4e087148842fd1979c9b658690 163 Gene3D G3DSA:3.90.80.10 2 159 3.6E-54 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 LK06_RS05530 524bd64a4ecc95379cdb265ee616f986 399 Gene3D G3DSA:1.10.150.130 45 153 2.1E-9 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS05530 524bd64a4ecc95379cdb265ee616f986 399 SUPERFAMILY SSF56349 194 372 1.94E-32 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS05530 524bd64a4ecc95379cdb265ee616f986 399 Pfam PF00589 Phage integrase family 208 362 2.4E-21 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS05530 524bd64a4ecc95379cdb265ee616f986 399 Gene3D G3DSA:1.10.443.10 207 369 3.0E-33 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS18575 649a4b1a5e893c1d4bf40e661751938c 190 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 184 4.1E-29 T 06-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 LK06_RS18575 649a4b1a5e893c1d4bf40e661751938c 190 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 186 21.255 T 06-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 LK06_RS18575 649a4b1a5e893c1d4bf40e661751938c 190 SUPERFAMILY SSF55144 1 188 1.92E-35 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase LK06_RS18575 649a4b1a5e893c1d4bf40e661751938c 190 Gene3D G3DSA:3.90.1140.10 1 188 1.7E-48 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase LK06_RS18575 649a4b1a5e893c1d4bf40e661751938c 190 Pfam PF02834 LigT like Phosphoesterase 9 90 8.3E-14 T 06-07-2017 IPR014051 Phosphoesterase, HXTX LK06_RS18575 649a4b1a5e893c1d4bf40e661751938c 190 Pfam PF02834 LigT like Phosphoesterase 98 171 1.2E-6 T 06-07-2017 IPR014051 Phosphoesterase, HXTX LK06_RS17330 a8fb77c21b208bd8bca9edb52570e31b 182 Pfam PF12802 MarR family 55 112 3.6E-12 T 06-07-2017 LK06_RS17330 a8fb77c21b208bd8bca9edb52570e31b 182 SMART SM00347 50 153 1.6E-21 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17330 a8fb77c21b208bd8bca9edb52570e31b 182 ProSitePatterns PS00519 AsnC-type HTH domain signature. 78 104 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LK06_RS17330 a8fb77c21b208bd8bca9edb52570e31b 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 3.9E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17330 a8fb77c21b208bd8bca9edb52570e31b 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 3.9E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17330 a8fb77c21b208bd8bca9edb52570e31b 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 3.9E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17330 a8fb77c21b208bd8bca9edb52570e31b 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 143 163 3.9E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17330 a8fb77c21b208bd8bca9edb52570e31b 182 Gene3D G3DSA:1.10.10.10 20 169 4.2E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17330 a8fb77c21b208bd8bca9edb52570e31b 182 SUPERFAMILY SSF46785 26 167 2.67E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15425 92fedee221a2c9edcc2a91791146c766 365 Gene3D G3DSA:3.40.50.720 137 277 1.1E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15425 92fedee221a2c9edcc2a91791146c766 365 SUPERFAMILY SSF51735 141 280 6.19E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15425 92fedee221a2c9edcc2a91791146c766 365 Gene3D G3DSA:1.10.287.70 36 133 1.1E-16 T 06-07-2017 LK06_RS15425 92fedee221a2c9edcc2a91791146c766 365 Pfam PF02254 TrkA-N domain 146 262 1.4E-25 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LK06_RS15425 92fedee221a2c9edcc2a91791146c766 365 Pfam PF07885 Ion channel 42 125 1.4E-13 T 06-07-2017 IPR013099 Potassium channel domain LK06_RS15425 92fedee221a2c9edcc2a91791146c766 365 SUPERFAMILY SSF81324 31 159 7.98E-22 T 06-07-2017 LK06_RS11610 b6295920d022301d246560d0c7b029ac 1317 Pfam PF01580 FtsK/SpoIIIE family 980 1095 6.3E-13 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS11610 b6295920d022301d246560d0c7b029ac 1317 SMART SM00382 988 1212 1.2E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS11610 b6295920d022301d246560d0c7b029ac 1317 Gene3D G3DSA:2.60.200.20 100 201 2.9E-24 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS11610 b6295920d022301d246560d0c7b029ac 1317 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 113 202 5.9E-16 T 06-07-2017 IPR032030 YscD, cytoplasmic domain LK06_RS11610 b6295920d022301d246560d0c7b029ac 1317 SMART SM00240 127 178 4.4E-13 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS11610 b6295920d022301d246560d0c7b029ac 1317 Gene3D G3DSA:3.40.50.300 973 1094 2.8E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11610 b6295920d022301d246560d0c7b029ac 1317 Gene3D G3DSA:3.40.50.300 1137 1187 2.8E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11610 b6295920d022301d246560d0c7b029ac 1317 SUPERFAMILY SSF52540 950 1187 1.98E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11610 b6295920d022301d246560d0c7b029ac 1317 SUPERFAMILY SSF49879 93 200 2.68E-25 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS12975 61b00f64665dd3b04a3597eb183d5c65 111 Pfam PF03793 PASTA domain 10 70 1.1E-6 T 06-07-2017 IPR005543 PASTA domain LK06_RS12790 250e525cfc7839c65caccca7138388bd 548 Gene3D G3DSA:3.40.50.980 4 150 9.3E-33 T 06-07-2017 LK06_RS12790 250e525cfc7839c65caccca7138388bd 548 Pfam PF00501 AMP-binding enzyme 8 394 7.5E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS12790 250e525cfc7839c65caccca7138388bd 548 Gene3D G3DSA:2.30.38.10 311 385 1.4E-19 T 06-07-2017 LK06_RS12790 250e525cfc7839c65caccca7138388bd 548 SUPERFAMILY SSF56801 3 481 1.19E-118 T 06-07-2017 LK06_RS12790 250e525cfc7839c65caccca7138388bd 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS12790 250e525cfc7839c65caccca7138388bd 548 Gene3D G3DSA:3.30.300.30 389 477 4.4E-14 T 06-07-2017 LK06_RS12790 250e525cfc7839c65caccca7138388bd 548 Gene3D G3DSA:3.40.50.980 151 310 1.4E-35 T 06-07-2017 LK06_RS29585 1ad97c1f271a72f2f960554f6746257e 95 SUPERFAMILY SSF53720 1 71 4.97E-19 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS29585 1ad97c1f271a72f2f960554f6746257e 95 Gene3D G3DSA:3.40.309.10 1 66 1.2E-18 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS29585 1ad97c1f271a72f2f960554f6746257e 95 Pfam PF00171 Aldehyde dehydrogenase family 1 63 4.0E-20 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS18020 4a88024c00aa9943741a7b14d289595d 160 Pfam PF14015 Protein of unknown function (DUF4231) 31 96 1.8E-6 T 06-07-2017 IPR025325 Protein of unknown function DUF4231 LK06_RS07965 3601e0e42daaed96c9ba8c1e6977a849 354 Gene3D G3DSA:3.20.20.30 1 353 4.0E-82 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS07965 3601e0e42daaed96c9ba8c1e6977a849 354 Pfam PF00296 Luciferase-like monooxygenase 1 315 3.1E-56 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS07965 3601e0e42daaed96c9ba8c1e6977a849 354 SUPERFAMILY SSF51679 1 353 7.59E-75 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 509 33.894 T 06-07-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 SUPERFAMILY SSF53187 189 504 3.77E-113 T 06-07-2017 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 355 362 - T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 PRINTS PR00481 Cytosol aminopeptidase signature 270 287 5.6E-49 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 PRINTS PR00481 Cytosol aminopeptidase signature 351 371 5.6E-49 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 PRINTS PR00481 Cytosol aminopeptidase signature 329 350 5.6E-49 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 PRINTS PR00481 Cytosol aminopeptidase signature 379 394 5.6E-49 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 PRINTS PR00481 Cytosol aminopeptidase signature 292 313 5.6E-49 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 Gene3D G3DSA:3.40.220.10 16 187 4.7E-38 T 06-07-2017 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 SUPERFAMILY SSF52949 17 149 2.35E-25 T 06-07-2017 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 Gene3D G3DSA:3.40.630.10 188 505 1.4E-130 T 06-07-2017 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 146 9.3E-26 T 06-07-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 LK06_RS07790 954eb89d5ea5cf03b064cafb8a1e4f66 513 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 196 501 7.6E-115 T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 LK06_RS11910 0e6e1239d1a1442b3264ada31c363afc 319 Gene3D G3DSA:3.40.50.10680 87 317 4.8E-84 T 06-07-2017 LK06_RS11910 0e6e1239d1a1442b3264ada31c363afc 319 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 319 138.884 T 06-07-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 LK06_RS11910 0e6e1239d1a1442b3264ada31c363afc 319 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 309 3.8E-136 T 06-07-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 LK06_RS11910 0e6e1239d1a1442b3264ada31c363afc 319 Pfam PF01933 Uncharacterised protein family UPF0052 3 283 5.3E-65 T 06-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 LK06_RS11910 0e6e1239d1a1442b3264ada31c363afc 319 SUPERFAMILY SSF142338 3 315 3.01E-86 T 06-07-2017 LK06_RS18170 4926e13e47cf8bf8d031233070b3cc0d 160 SUPERFAMILY SSF55729 1 150 7.6E-38 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS18170 4926e13e47cf8bf8d031233070b3cc0d 160 Pfam PF00583 Acetyltransferase (GNAT) family 56 136 1.2E-17 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS18170 4926e13e47cf8bf8d031233070b3cc0d 160 Gene3D G3DSA:3.40.630.30 2 155 4.1E-56 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS21860 1c4b7953a75d346775b7a81c644eb657 347 Pfam PF00005 ABC transporter 36 186 3.0E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS21860 1c4b7953a75d346775b7a81c644eb657 347 SMART SM00382 44 236 3.2E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS21860 1c4b7953a75d346775b7a81c644eb657 347 Gene3D G3DSA:3.40.50.300 6 260 1.2E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21860 1c4b7953a75d346775b7a81c644eb657 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 327 3.1E-27 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21860 1c4b7953a75d346775b7a81c644eb657 347 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS21860 1c4b7953a75d346775b7a81c644eb657 347 SUPERFAMILY SSF52540 7 258 7.88E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21860 1c4b7953a75d346775b7a81c644eb657 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 304 2.8E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 SUPERFAMILY SSF51971 263 348 5.53E-5 T 06-07-2017 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 Gene3D G3DSA:3.50.50.60 274 350 7.8E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 Gene3D G3DSA:3.50.50.60 5 135 1.8E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 1.2E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.2E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 131 1.2E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 SUPERFAMILY SSF51905 135 284 4.07E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 Gene3D G3DSA:3.50.50.60 136 202 1.4E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 Gene3D G3DSA:3.50.50.60 249 273 1.4E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 SUPERFAMILY SSF51905 1 184 6.95E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 291 1.7E-11 T 06-07-2017 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-11 T 06-07-2017 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 1.7E-11 T 06-07-2017 LK06_RS13230 734f415b2e07a5b92f948e986cd18a7d 351 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 196 6.6E-27 T 06-07-2017 LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 PIRSF PIRSF001259 17 424 3.9E-175 T 06-07-2017 LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 225 414 2.7E-73 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 16 220 38.285 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 221 417 41.079 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 22 215 3.8E-84 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 19 216 7.2E-73 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 SUPERFAMILY SSF55821 15 218 2.98E-81 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 Pfam PF00925 GTP cyclohydrolase II 224 390 2.8E-72 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 17 413 54.044 T 06-07-2017 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 SUPERFAMILY SSF142695 222 393 1.18E-69 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS03945 6724349c2fc1c982150d43800e5138a7 445 Gene3D G3DSA:3.90.870.10 15 228 9.3E-96 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain LK06_RS17785 392fdffe99a7c0e3a4e7bd6c54e14915 383 Gene3D G3DSA:3.90.1720.10 265 370 1.0E-38 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS17785 392fdffe99a7c0e3a4e7bd6c54e14915 383 SUPERFAMILY SSF54001 267 376 3.24E-35 T 06-07-2017 LK06_RS17785 392fdffe99a7c0e3a4e7bd6c54e14915 383 Pfam PF00877 NlpC/P60 family 282 365 2.0E-20 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS07300 1263c5fddb255d955822945ddf57b71c 362 Gene3D G3DSA:3.40.50.2000 2 187 4.4E-62 T 06-07-2017 LK06_RS07300 1263c5fddb255d955822945ddf57b71c 362 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 358 32.031 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LK06_RS07300 1263c5fddb255d955822945ddf57b71c 362 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 351 1.4E-89 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LK06_RS07300 1263c5fddb255d955822945ddf57b71c 362 Gene3D G3DSA:3.40.50.2000 188 343 3.0E-18 T 06-07-2017 LK06_RS07300 1263c5fddb255d955822945ddf57b71c 362 SUPERFAMILY SSF53756 2 358 2.47E-101 T 06-07-2017 LK06_RS07300 1263c5fddb255d955822945ddf57b71c 362 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 6.2E-45 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LK06_RS07300 1263c5fddb255d955822945ddf57b71c 362 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 348 5.0E-42 T 06-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 LK06_RS30945 c0992ff44ace6b3ce407e3f5e7e40021 144 Pfam PF13581 Histidine kinase-like ATPase domain 24 137 4.0E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS30945 c0992ff44ace6b3ce407e3f5e7e40021 144 Gene3D G3DSA:3.30.565.10 29 138 2.6E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS30945 c0992ff44ace6b3ce407e3f5e7e40021 144 SUPERFAMILY SSF55874 44 139 4.58E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS02845 87797362acc0cb722ee81ef2cfe25556 253 Gene3D G3DSA:3.40.1410.10 72 236 5.6E-23 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS02845 87797362acc0cb722ee81ef2cfe25556 253 Gene3D G3DSA:1.10.10.10 10 71 8.7E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02845 87797362acc0cb722ee81ef2cfe25556 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS02845 87797362acc0cb722ee81ef2cfe25556 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS02845 87797362acc0cb722ee81ef2cfe25556 253 SUPERFAMILY SSF46785 12 79 5.79E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02845 87797362acc0cb722ee81ef2cfe25556 253 SMART SM00345 17 75 4.0E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS02845 87797362acc0cb722ee81ef2cfe25556 253 SMART SM00866 94 233 4.2E-13 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS02845 87797362acc0cb722ee81ef2cfe25556 253 Pfam PF07702 UTRA domain 106 231 7.0E-15 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS02845 87797362acc0cb722ee81ef2cfe25556 253 SUPERFAMILY SSF64288 63 236 4.24E-26 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS02845 87797362acc0cb722ee81ef2cfe25556 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 75 6.1E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS09615 0b12f70a0cb3336014330d8946d95834 580 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 488 575 3.0E-12 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain LK06_RS09615 0b12f70a0cb3336014330d8946d95834 580 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 294 406 3.7E-6 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS28540 57685b186ad949faefb838da9d6e2354 358 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 330 6.5E-16 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 LK06_RS28540 57685b186ad949faefb838da9d6e2354 358 SUPERFAMILY SSF50249 200 339 8.22E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS28540 57685b186ad949faefb838da9d6e2354 358 Pfam PF01068 ATP dependent DNA ligase domain 11 197 1.8E-39 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 LK06_RS28540 57685b186ad949faefb838da9d6e2354 358 Gene3D G3DSA:2.40.50.140 200 336 3.2E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS28540 57685b186ad949faefb838da9d6e2354 358 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 27 35 - T 06-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 LK06_RS28540 57685b186ad949faefb838da9d6e2354 358 Gene3D G3DSA:3.30.470.30 32 148 1.1E-29 T 06-07-2017 LK06_RS28540 57685b186ad949faefb838da9d6e2354 358 SUPERFAMILY SSF56091 6 197 2.4E-41 T 06-07-2017 LK06_RS28540 57685b186ad949faefb838da9d6e2354 358 Gene3D G3DSA:3.30.1490.70 3 31 1.3E-10 T 06-07-2017 LK06_RS28540 57685b186ad949faefb838da9d6e2354 358 Gene3D G3DSA:3.30.1490.70 156 198 1.3E-10 T 06-07-2017 LK06_RS10830 95aa54034a63f0032068706f697349fc 494 Gene3D G3DSA:3.20.20.80 238 469 1.4E-11 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS10830 95aa54034a63f0032068706f697349fc 494 Pfam PF00704 Glycosyl hydrolases family 18 253 461 2.0E-9 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 LK06_RS10830 95aa54034a63f0032068706f697349fc 494 Pfam PF00553 Cellulose binding domain 41 138 5.7E-20 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 LK06_RS10830 95aa54034a63f0032068706f697349fc 494 Gene3D G3DSA:2.60.40.290 39 140 1.6E-27 T 06-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 LK06_RS10830 95aa54034a63f0032068706f697349fc 494 SMART SM00637 40 138 8.8E-29 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 LK06_RS10830 95aa54034a63f0032068706f697349fc 494 SUPERFAMILY SSF49384 36 140 1.46E-24 T 06-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 LK06_RS10830 95aa54034a63f0032068706f697349fc 494 SUPERFAMILY SSF51445 202 464 6.79E-24 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS01540 87fdd812bb6c0e8cd98cc1f589b42ab2 258 Gene3D G3DSA:3.60.20.10 1 243 1.1E-42 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS01540 87fdd812bb6c0e8cd98cc1f589b42ab2 258 SUPERFAMILY SSF56235 2 243 7.72E-17 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS01540 87fdd812bb6c0e8cd98cc1f589b42ab2 258 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 246 42.44 T 06-07-2017 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00311+3.5.1.11|KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255 LK06_RS01540 87fdd812bb6c0e8cd98cc1f589b42ab2 258 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 245 5.7E-91 T 06-07-2017 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 LK06_RS01540 87fdd812bb6c0e8cd98cc1f589b42ab2 258 Pfam PF13522 Glutamine amidotransferase domain 71 217 7.9E-17 T 06-07-2017 LK06_RS03155 3b07ec72943a013c3face22436fa5cd2 433 Pfam PF01610 Transposase 178 415 1.5E-52 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain LK06_RS03155 3b07ec72943a013c3face22436fa5cd2 433 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 86 137 3.4E-10 T 06-07-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain LK06_RS03155 3b07ec72943a013c3face22436fa5cd2 433 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 33 76 3.0E-8 T 06-07-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger LK06_RS32350 3b07ec72943a013c3face22436fa5cd2 433 Pfam PF01610 Transposase 178 415 1.5E-52 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain LK06_RS32350 3b07ec72943a013c3face22436fa5cd2 433 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 86 137 3.4E-10 T 06-07-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain LK06_RS32350 3b07ec72943a013c3face22436fa5cd2 433 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 33 76 3.0E-8 T 06-07-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger LK06_RS22180 dc74c6f8790b76a1ddf7eb27327e5312 518 SUPERFAMILY SSF53474 113 166 3.6E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22180 dc74c6f8790b76a1ddf7eb27327e5312 518 SUPERFAMILY SSF53474 211 265 3.6E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22180 dc74c6f8790b76a1ddf7eb27327e5312 518 SUPERFAMILY SSF53474 344 505 3.6E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22180 dc74c6f8790b76a1ddf7eb27327e5312 518 Pfam PF08386 TAP-like protein 412 517 1.9E-33 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal LK06_RS22180 dc74c6f8790b76a1ddf7eb27327e5312 518 Gene3D G3DSA:3.40.50.1820 82 165 7.6E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22180 dc74c6f8790b76a1ddf7eb27327e5312 518 Gene3D G3DSA:3.40.50.1820 209 335 7.6E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22180 dc74c6f8790b76a1ddf7eb27327e5312 518 Gene3D G3DSA:3.40.50.1820 383 505 7.6E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28940 a15d2c2d53f773d6dd3f036a8eb655a4 261 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 9 229 2.5E-40 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA LK06_RS28940 a15d2c2d53f773d6dd3f036a8eb655a4 261 Gene3D G3DSA:3.40.50.1000 4 79 5.0E-40 T 06-07-2017 IPR023214 HAD-like domain LK06_RS28940 a15d2c2d53f773d6dd3f036a8eb655a4 261 Gene3D G3DSA:3.40.50.1000 178 257 5.0E-40 T 06-07-2017 IPR023214 HAD-like domain LK06_RS28940 a15d2c2d53f773d6dd3f036a8eb655a4 261 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 99 7.1E-17 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA LK06_RS28940 a15d2c2d53f773d6dd3f036a8eb655a4 261 SUPERFAMILY SSF56784 6 254 4.0E-55 T 06-07-2017 IPR023214 HAD-like domain LK06_RS28940 a15d2c2d53f773d6dd3f036a8eb655a4 261 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 174 220 1.1E-5 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS28940 a15d2c2d53f773d6dd3f036a8eb655a4 261 Pfam PF13242 HAD-hyrolase-like 180 253 4.1E-20 T 06-07-2017 LK06_RS28940 a15d2c2d53f773d6dd3f036a8eb655a4 261 Gene3D G3DSA:3.40.50.10410 80 177 2.2E-30 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain LK06_RS29395 ca5f30f9788835b244214141c9a82710 173 Pfam PF01625 Peptide methionine sulfoxide reductase 8 154 1.9E-56 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LK06_RS29395 ca5f30f9788835b244214141c9a82710 173 SUPERFAMILY SSF55068 4 162 5.36E-64 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LK06_RS29395 ca5f30f9788835b244214141c9a82710 173 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 7 154 1.2E-49 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LK06_RS29395 ca5f30f9788835b244214141c9a82710 173 Gene3D G3DSA:3.30.1060.10 4 155 8.6E-65 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LK06_RS29395 ca5f30f9788835b244214141c9a82710 173 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 160 33.76 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LK06_RS24010 822d1db5e77f06922ed6a43d0f9163b9 543 SUPERFAMILY SSF53720 7 527 4.45E-124 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS24010 822d1db5e77f06922ed6a43d0f9163b9 543 Gene3D G3DSA:3.40.605.10 41 302 3.6E-64 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS24010 822d1db5e77f06922ed6a43d0f9163b9 543 Gene3D G3DSA:3.40.309.10 303 501 2.9E-42 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS24010 822d1db5e77f06922ed6a43d0f9163b9 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 321 332 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 LK06_RS24010 822d1db5e77f06922ed6a43d0f9163b9 543 Pfam PF00171 Aldehyde dehydrogenase family 56 526 7.1E-102 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS24010 822d1db5e77f06922ed6a43d0f9163b9 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 542 3.4E-242 T 06-07-2017 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-70688 LK06_RS22270 ee6d56cf5e0851b979fc5b8663344268 226 Pfam PF01987 Mitochondrial biogenesis AIM24 21 214 3.5E-36 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS22270 ee6d56cf5e0851b979fc5b8663344268 226 SUPERFAMILY SSF51219 18 217 8.63E-49 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain LK06_RS22270 ee6d56cf5e0851b979fc5b8663344268 226 Gene3D G3DSA:3.60.160.10 13 216 1.2E-42 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS11005 a2afe5367d135005ec8eb44532615e6e 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 231 2.4E-45 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA LK06_RS11005 a2afe5367d135005ec8eb44532615e6e 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 109 2.0E-26 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA LK06_RS11005 a2afe5367d135005ec8eb44532615e6e 259 Gene3D G3DSA:3.40.50.10410 88 181 4.4E-33 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain LK06_RS11005 a2afe5367d135005ec8eb44532615e6e 259 Pfam PF13242 HAD-hyrolase-like 182 255 3.1E-21 T 06-07-2017 LK06_RS11005 a2afe5367d135005ec8eb44532615e6e 259 PIRSF PIRSF000915 4 259 1.3E-52 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA LK06_RS11005 a2afe5367d135005ec8eb44532615e6e 259 SUPERFAMILY SSF56784 7 256 3.02E-67 T 06-07-2017 IPR023214 HAD-like domain LK06_RS11005 a2afe5367d135005ec8eb44532615e6e 259 Gene3D G3DSA:3.40.50.1000 182 258 1.9E-41 T 06-07-2017 IPR023214 HAD-like domain LK06_RS11005 a2afe5367d135005ec8eb44532615e6e 259 Gene3D G3DSA:3.40.50.1000 6 83 1.9E-41 T 06-07-2017 IPR023214 HAD-like domain LK06_RS16330 35490f6cec9fd856af98554600f40771 513 Gene3D G3DSA:2.30.42.10 458 511 9.8E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 Gene3D G3DSA:2.40.10.10 294 405 3.5E-41 T 06-07-2017 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 SUPERFAMILY SSF50156 398 506 5.26E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 Pfam PF13180 PDZ domain 418 506 1.3E-24 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 Pfam PF13365 Trypsin-like peptidase domain 224 370 1.3E-33 T 06-07-2017 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 SUPERFAMILY SSF50494 198 410 2.17E-54 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS16330 35490f6cec9fd856af98554600f40771 513 Gene3D G3DSA:2.40.10.10 190 293 4.3E-25 T 06-07-2017 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 SMART SM00228 417 497 5.5E-4 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 Gene3D G3DSA:2.30.42.10 406 457 2.6E-5 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 PRINTS PR00834 HtrA/DegQ protease family signature 257 277 2.6E-46 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 PRINTS PR00834 HtrA/DegQ protease family signature 233 245 2.6E-46 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 PRINTS PR00834 HtrA/DegQ protease family signature 299 323 2.6E-46 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 PRINTS PR00834 HtrA/DegQ protease family signature 455 467 2.6E-46 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 PRINTS PR00834 HtrA/DegQ protease family signature 363 380 2.6E-46 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS16330 35490f6cec9fd856af98554600f40771 513 PRINTS PR00834 HtrA/DegQ protease family signature 341 358 2.6E-46 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 89 1.2E-8 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 SUPERFAMILY SSF48452 92 251 4.24E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 Pfam PF00931 NB-ARC domain 304 534 7.1E-12 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 PRINTS PR00364 Disease resistance protein signature 387 401 7.6E-12 T 06-07-2017 LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 PRINTS PR00364 Disease resistance protein signature 472 486 7.6E-12 T 06-07-2017 LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 PRINTS PR00364 Disease resistance protein signature 308 323 7.6E-12 T 06-07-2017 LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 SUPERFAMILY SSF52540 274 535 1.01E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 SUPERFAMILY SSF46894 2 89 4.82E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 SMART SM01043 96 240 4.2E-44 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 SMART SM00862 15 89 2.2E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 Pfam PF03704 Bacterial transcriptional activator domain 96 240 1.4E-41 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 Gene3D G3DSA:3.40.50.300 306 401 7.6E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 Gene3D G3DSA:1.10.10.10 552 600 3.6E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12875 4daf242838067ed49a1ae4e18402d85a 607 Gene3D G3DSA:1.10.10.10 23 91 2.3E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17625 a9a193755fd7b2a13a974f42f53d788e 245 Pfam PF11209 Protein of unknown function (DUF2993) 21 235 1.4E-26 T 06-07-2017 IPR021373 Protein of unknown function DUF2993 LK06_RS19995 8c2ddb4351dcd0aa45f91f3d06896ea5 273 Pfam PF00005 ABC transporter 34 180 2.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS19995 8c2ddb4351dcd0aa45f91f3d06896ea5 273 SUPERFAMILY SSF52540 17 233 2.18E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19995 8c2ddb4351dcd0aa45f91f3d06896ea5 273 Gene3D G3DSA:3.40.50.300 17 234 1.5E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS19995 8c2ddb4351dcd0aa45f91f3d06896ea5 273 SMART SM00382 43 229 2.2E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS19995 8c2ddb4351dcd0aa45f91f3d06896ea5 273 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS31560 a9fa8f0b28182c647031504fd9bfca65 318 Pfam PF14525 AraC-binding-like domain 37 184 6.6E-10 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LK06_RS31560 a9fa8f0b28182c647031504fd9bfca65 318 Gene3D G3DSA:1.10.10.60 212 261 4.1E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS31560 a9fa8f0b28182c647031504fd9bfca65 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 262 306 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LK06_RS31560 a9fa8f0b28182c647031504fd9bfca65 318 SMART SM00342 226 310 2.6E-28 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS31560 a9fa8f0b28182c647031504fd9bfca65 318 Pfam PF12833 Helix-turn-helix domain 232 311 2.7E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LK06_RS31560 a9fa8f0b28182c647031504fd9bfca65 318 SUPERFAMILY SSF46689 261 313 2.72E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS31560 a9fa8f0b28182c647031504fd9bfca65 318 Gene3D G3DSA:1.10.10.60 262 313 4.7E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS31560 a9fa8f0b28182c647031504fd9bfca65 318 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 294 310 3.3E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LK06_RS31560 a9fa8f0b28182c647031504fd9bfca65 318 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 279 294 3.3E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LK06_RS11950 9056b6fb65349db196e6afaf36e7163e 354 Pfam PF00535 Glycosyl transferase family 2 13 182 2.0E-21 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS11950 9056b6fb65349db196e6afaf36e7163e 354 SUPERFAMILY SSF53448 8 256 2.63E-44 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11950 9056b6fb65349db196e6afaf36e7163e 354 Gene3D G3DSA:3.90.550.10 10 247 6.5E-37 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS03940 dc7dffd6fe5cb7d0a1edb086b0b9dbd8 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 151 2.5E-52 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS03940 dc7dffd6fe5cb7d0a1edb086b0b9dbd8 161 Gene3D G3DSA:3.40.50.960 11 157 4.5E-60 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS03940 dc7dffd6fe5cb7d0a1edb086b0b9dbd8 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 151 1.2E-43 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS03940 dc7dffd6fe5cb7d0a1edb086b0b9dbd8 161 SUPERFAMILY SSF52121 10 156 7.98E-56 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS03940 dc7dffd6fe5cb7d0a1edb086b0b9dbd8 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 156 28.865 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS13725 5ece77718d3e1ff36bedf42bfb7398a9 398 SUPERFAMILY SSF55874 270 394 2.29E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13725 5ece77718d3e1ff36bedf42bfb7398a9 398 Gene3D G3DSA:3.30.565.10 273 396 2.9E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13725 5ece77718d3e1ff36bedf42bfb7398a9 398 Pfam PF07730 Histidine kinase 187 252 2.4E-20 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS13725 5ece77718d3e1ff36bedf42bfb7398a9 398 SMART SM00387 297 396 0.0045 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13725 5ece77718d3e1ff36bedf42bfb7398a9 398 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 299 395 2.5E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS08415 0b21ed290b238cfd739f718d9f2b2464 221 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 131 144 - T 06-07-2017 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 LK06_RS08415 0b21ed290b238cfd739f718d9f2b2464 221 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 13 211 1.0E-73 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 LK06_RS08415 0b21ed290b238cfd739f718d9f2b2464 221 Pfam PF01081 KDPG and KHG aldolase 13 206 8.7E-71 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 LK06_RS08415 0b21ed290b238cfd739f718d9f2b2464 221 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 43 52 - T 06-07-2017 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 LK06_RS08415 0b21ed290b238cfd739f718d9f2b2464 221 SUPERFAMILY SSF51569 13 213 4.03E-66 T 06-07-2017 LK06_RS08415 0b21ed290b238cfd739f718d9f2b2464 221 Gene3D G3DSA:3.20.20.70 14 213 3.6E-74 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS00765 ce113d5f348377a48b31c0522d95ee94 218 Pfam PF13302 Acetyltransferase (GNAT) domain 32 185 9.9E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS00765 ce113d5f348377a48b31c0522d95ee94 218 SUPERFAMILY SSF55729 25 207 4.94E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS00765 ce113d5f348377a48b31c0522d95ee94 218 Gene3D G3DSA:3.40.630.30 27 207 4.8E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS25075 76f966f47b9c83fa882944e1de4ef25f 258 Pfam PF00005 ABC transporter 33 181 5.8E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS25075 76f966f47b9c83fa882944e1de4ef25f 258 SMART SM00382 42 229 7.3E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS25075 76f966f47b9c83fa882944e1de4ef25f 258 Gene3D G3DSA:3.40.50.300 17 253 1.1E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25075 76f966f47b9c83fa882944e1de4ef25f 258 PIRSF PIRSF039085 14 257 4.5E-113 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LK06_RS25075 76f966f47b9c83fa882944e1de4ef25f 258 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS25075 76f966f47b9c83fa882944e1de4ef25f 258 SUPERFAMILY SSF52540 18 251 3.59E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12500 6c773ccb2486565d21f0f172e2e231e8 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 2.0E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS12500 6c773ccb2486565d21f0f172e2e231e8 186 SUPERFAMILY SSF46689 3 75 8.21E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS12500 6c773ccb2486565d21f0f172e2e231e8 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 4.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS12500 6c773ccb2486565d21f0f172e2e231e8 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 4.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS12500 6c773ccb2486565d21f0f172e2e231e8 186 Gene3D G3DSA:1.10.357.10 3 147 2.7E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS30130 934121918b94e3d77d03dd6404acbcc4 261 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 67 75 - T 06-07-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS30130 934121918b94e3d77d03dd6404acbcc4 261 Pfam PF01177 Asp/Glu/Hydantoin racemase 45 194 5.8E-13 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS30130 934121918b94e3d77d03dd6404acbcc4 261 SUPERFAMILY SSF53681 106 238 1.2E-16 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS30130 934121918b94e3d77d03dd6404acbcc4 261 SUPERFAMILY SSF53681 2 102 1.57E-22 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS30130 934121918b94e3d77d03dd6404acbcc4 261 Gene3D G3DSA:3.40.50.1860 2 157 1.2E-33 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS23820 fbcf5426baed87e65ad6d18b6cbe1c8c 208 Gene3D G3DSA:1.10.357.10 8 196 1.7E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS23820 fbcf5426baed87e65ad6d18b6cbe1c8c 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 61 2.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23820 fbcf5426baed87e65ad6d18b6cbe1c8c 208 SUPERFAMILY SSF46689 7 79 3.26E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 Gene3D G3DSA:3.40.50.2300 4 151 4.0E-42 T 06-07-2017 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 1.2E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 SMART SM00421 149 206 2.1E-28 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 SUPERFAMILY SSF46894 145 211 3.4E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 Pfam PF00072 Response regulator receiver domain 7 118 3.3E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 3.2E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 3.2E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 3.2E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 SMART SM00448 5 118 1.1E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 Gene3D G3DSA:1.10.10.10 152 211 1.3E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05920 74731a6b979ee3edf2683a0695b5e155 213 SUPERFAMILY SSF52172 5 135 3.13E-37 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS14170 edeb2e6df86427877e66bb1cbe1cae63 129 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 18 91 18.862 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS14170 edeb2e6df86427877e66bb1cbe1cae63 129 Pfam PF02467 Transcription factor WhiB 24 86 1.3E-24 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS20410 1bb4dff84d183a59f909da136c97a179 506 SUPERFAMILY SSF53720 10 496 2.36E-159 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS20410 1bb4dff84d183a59f909da136c97a179 506 Gene3D G3DSA:3.40.309.10 269 467 7.1E-65 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS20410 1bb4dff84d183a59f909da136c97a179 506 Gene3D G3DSA:3.40.605.10 13 268 2.0E-89 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS20410 1bb4dff84d183a59f909da136c97a179 506 Pfam PF00171 Aldehyde dehydrogenase family 19 492 2.9E-162 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS20410 1bb4dff84d183a59f909da136c97a179 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 290 301 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 LK06_RS20410 1bb4dff84d183a59f909da136c97a179 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 LK06_RS31670 0e8d59d61d93e1b51fb45333d42dc6cf 237 SUPERFAMILY SSF51055 185 237 8.76E-16 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS31670 0e8d59d61d93e1b51fb45333d42dc6cf 237 Pfam PF02839 Carbohydrate binding domain 190 231 1.2E-11 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS31670 0e8d59d61d93e1b51fb45333d42dc6cf 237 SUPERFAMILY SSF81296 32 172 6.3E-35 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS31670 0e8d59d61d93e1b51fb45333d42dc6cf 237 Gene3D G3DSA:2.70.50.50 32 172 1.3E-30 T 06-07-2017 LK06_RS31670 0e8d59d61d93e1b51fb45333d42dc6cf 237 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 169 4.2E-16 T 06-07-2017 IPR004302 Chitin-binding protein, N-terminal LK06_RS31670 0e8d59d61d93e1b51fb45333d42dc6cf 237 SMART SM00495 189 234 6.9E-14 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS31670 0e8d59d61d93e1b51fb45333d42dc6cf 237 Gene3D G3DSA:2.10.10.20 187 234 9.0E-20 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 LK06_RS12990 68a842c00c50352e2853382f9a34d64c 399 PIRSF PIRSF004762 1 372 2.5E-108 T 06-07-2017 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 LK06_RS12990 68a842c00c50352e2853382f9a34d64c 399 Pfam PF04055 Radical SAM superfamily 65 238 1.9E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS12990 68a842c00c50352e2853382f9a34d64c 399 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 19 360 2.3E-140 T 06-07-2017 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 LK06_RS12990 68a842c00c50352e2853382f9a34d64c 399 Gene3D G3DSA:3.20.20.70 18 352 9.5E-64 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS12990 68a842c00c50352e2853382f9a34d64c 399 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 360 3.0E-105 T 06-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 LK06_RS12990 68a842c00c50352e2853382f9a34d64c 399 SMART SM00729 54 281 0.0072 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS12990 68a842c00c50352e2853382f9a34d64c 399 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 17 363 51.043 T 06-07-2017 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 LK06_RS12990 68a842c00c50352e2853382f9a34d64c 399 SUPERFAMILY SSF102114 17 352 2.09E-51 T 06-07-2017 LK06_RS23690 6d4f781d61d06f68b96604eaf1940469 407 SUPERFAMILY SSF141523 251 376 1.57E-20 T 06-07-2017 LK06_RS23690 6d4f781d61d06f68b96604eaf1940469 407 Gene3D G3DSA:2.40.440.10 251 377 3.7E-16 T 06-07-2017 LK06_RS23690 6d4f781d61d06f68b96604eaf1940469 407 Pfam PF03734 L,D-transpeptidase catalytic domain 248 374 1.1E-10 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 LK06_RS07720 4d72877e1672369be4eed26935b8de0a 263 Pfam PF04012 PspA/IM30 family 3 231 1.4E-30 T 06-07-2017 IPR007157 PspA/IM30 LK06_RS03625 48121925c9a8bccbba1bfa0ef3bf7dbb 227 SMART SM00422 69 141 4.0E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS03625 48121925c9a8bccbba1bfa0ef3bf7dbb 227 Pfam PF13411 MerR HTH family regulatory protein 73 139 2.6E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS03625 48121925c9a8bccbba1bfa0ef3bf7dbb 227 SUPERFAMILY SSF46955 73 157 3.37E-14 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS03625 48121925c9a8bccbba1bfa0ef3bf7dbb 227 Gene3D G3DSA:1.10.1660.10 75 147 2.8E-13 T 06-07-2017 LK06_RS23945 cd0254930ad54e061b024b12ab2200f9 330 Gene3D G3DSA:3.40.50.720 58 117 3.1E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23945 cd0254930ad54e061b024b12ab2200f9 330 SUPERFAMILY SSF51735 102 282 1.38E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23945 cd0254930ad54e061b024b12ab2200f9 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LK06_RS23945 cd0254930ad54e061b024b12ab2200f9 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 281 3.6E-44 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LK06_RS23945 cd0254930ad54e061b024b12ab2200f9 330 SUPERFAMILY SSF52283 9 133 3.74E-6 T 06-07-2017 LK06_RS23945 cd0254930ad54e061b024b12ab2200f9 330 Gene3D G3DSA:3.40.50.720 118 282 9.0E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22335 ea15eb5d8de8a455e43524b4b30928ea 131 SUPERFAMILY SSF54631 1 122 1.11E-28 T 06-07-2017 LK06_RS22335 ea15eb5d8de8a455e43524b4b30928ea 131 Gene3D G3DSA:3.10.580.10 1 121 3.8E-30 T 06-07-2017 LK06_RS22335 ea15eb5d8de8a455e43524b4b30928ea 131 Pfam PF00571 CBS domain 3 55 1.4E-8 T 06-07-2017 IPR000644 CBS domain LK06_RS22335 ea15eb5d8de8a455e43524b4b30928ea 131 Pfam PF00571 CBS domain 73 120 1.5E-11 T 06-07-2017 IPR000644 CBS domain LK06_RS22335 ea15eb5d8de8a455e43524b4b30928ea 131 SMART SM00116 75 122 2.4E-6 T 06-07-2017 IPR000644 CBS domain LK06_RS22335 ea15eb5d8de8a455e43524b4b30928ea 131 SMART SM00116 10 58 8.6E-4 T 06-07-2017 IPR000644 CBS domain LK06_RS10340 ff2631a12b5c5f8e47caf36a370dd020 396 Pfam PF13692 Glycosyl transferases group 1 209 344 4.0E-34 T 06-07-2017 LK06_RS10340 ff2631a12b5c5f8e47caf36a370dd020 396 SUPERFAMILY SSF53756 18 382 3.93E-83 T 06-07-2017 LK06_RS10340 ff2631a12b5c5f8e47caf36a370dd020 396 Gene3D G3DSA:3.40.50.2000 167 357 9.7E-32 T 06-07-2017 LK06_RS10340 ff2631a12b5c5f8e47caf36a370dd020 396 Pfam PF13439 Glycosyltransferase Family 4 21 179 1.3E-30 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS14825 dcef93aa5e2b19d8778e904d6cb492d2 130 Pfam PF12680 SnoaL-like domain 23 108 4.4E-9 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain LK06_RS14825 dcef93aa5e2b19d8778e904d6cb492d2 130 Gene3D G3DSA:3.10.450.50 38 111 1.2E-5 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS14825 dcef93aa5e2b19d8778e904d6cb492d2 130 SUPERFAMILY SSF54427 23 111 7.18E-10 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS08755 679a8671b520e3e20b63f0fbb90986a5 401 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 384 1.2E-127 T 06-07-2017 LK06_RS08755 679a8671b520e3e20b63f0fbb90986a5 401 SUPERFAMILY SSF51621 36 264 7.32E-23 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS08755 679a8671b520e3e20b63f0fbb90986a5 401 SUPERFAMILY SSF51621 295 328 7.32E-23 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS08755 679a8671b520e3e20b63f0fbb90986a5 401 Gene3D G3DSA:3.20.20.60 36 328 3.1E-36 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS05590 c0aa8c7519f2add249b74e658caf25e1 396 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 389 1.9E-30 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS05590 c0aa8c7519f2add249b74e658caf25e1 396 Gene3D G3DSA:1.10.540.10 10 138 3.7E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS05590 c0aa8c7519f2add249b74e658caf25e1 396 SUPERFAMILY SSF47203 243 392 1.93E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS05590 c0aa8c7519f2add249b74e658caf25e1 396 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 140 230 3.9E-24 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS05590 c0aa8c7519f2add249b74e658caf25e1 396 SUPERFAMILY SSF56645 10 240 2.09E-74 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS05590 c0aa8c7519f2add249b74e658caf25e1 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 136 8.6E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS05590 c0aa8c7519f2add249b74e658caf25e1 396 Gene3D G3DSA:1.20.140.10 230 392 1.3E-41 T 06-07-2017 LK06_RS05590 c0aa8c7519f2add249b74e658caf25e1 396 Gene3D G3DSA:2.40.110.10 139 229 8.7E-38 T 06-07-2017 LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 SMART SM00487 26 228 3.2E-24 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 Gene3D G3DSA:3.40.50.2020 598 718 3.9E-7 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 26 363 5.6E-67 T 06-07-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 152 161 - T 06-07-2017 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site GO:0003676|GO:0005524|GO:0008026 LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 Pfam PF00271 Helicase conserved C-terminal domain 256 347 7.0E-13 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 Gene3D G3DSA:1.10.10.10 447 504 5.4E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 SUPERFAMILY SSF52540 75 367 2.2E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 SMART SM00490 267 348 3.7E-22 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 SUPERFAMILY SSF53271 672 718 2.07E-7 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 Gene3D G3DSA:3.40.50.300 21 210 3.3E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 Pfam PF00270 DEAD/DEAH box helicase 32 199 7.4E-16 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS25245 dc127ade6531d2975af74d61b77c6ce4 721 Gene3D G3DSA:3.40.50.300 222 371 1.2E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26265 83935e148a11f3b9882ed1b10d233bc4 348 Pfam PF00891 O-methyltransferase 140 310 9.0E-18 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 LK06_RS26265 83935e148a11f3b9882ed1b10d233bc4 348 Pfam PF16864 Dimerisation domain 35 107 7.9E-12 T 06-07-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain LK06_RS26265 83935e148a11f3b9882ed1b10d233bc4 348 SUPERFAMILY SSF53335 114 329 1.69E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26265 83935e148a11f3b9882ed1b10d233bc4 348 Gene3D G3DSA:1.10.10.10 34 98 3.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26265 83935e148a11f3b9882ed1b10d233bc4 348 SUPERFAMILY SSF46785 27 98 3.71E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26265 83935e148a11f3b9882ed1b10d233bc4 348 Gene3D G3DSA:3.40.50.150 120 330 2.5E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS21325 75a092dd3f5c1f0b1e3ad71622e777fd 164 Pfam PF02643 Uncharacterized ACR, COG1430 29 121 6.3E-14 T 06-07-2017 IPR003795 Protein of unknown function DUF192 LK06_RS05210 30ac4a6ade633891a755c22ff01773af 370 SMART SM00854 7 288 1.5E-105 T 06-07-2017 IPR019079 Capsule synthesis protein, CapA LK06_RS05210 30ac4a6ade633891a755c22ff01773af 370 Gene3D G3DSA:3.60.21.30 69 293 6.4E-10 T 06-07-2017 LK06_RS05210 30ac4a6ade633891a755c22ff01773af 370 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 8 288 1.9E-70 T 06-07-2017 IPR019079 Capsule synthesis protein, CapA LK06_RS05210 30ac4a6ade633891a755c22ff01773af 370 SUPERFAMILY SSF56300 12 17 5.06E-30 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS05210 30ac4a6ade633891a755c22ff01773af 370 SUPERFAMILY SSF56300 59 298 5.06E-30 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS00110 8c0cc280b89a5c51a450928b1be55a07 217 PIRSF PIRSF036990 6 216 5.3E-62 T 06-07-2017 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON LK06_RS00110 8c0cc280b89a5c51a450928b1be55a07 217 Pfam PF04972 BON domain 147 212 2.5E-11 T 06-07-2017 IPR007055 BON domain LK06_RS00110 8c0cc280b89a5c51a450928b1be55a07 217 SMART SM00116 96 144 7.5E-10 T 06-07-2017 IPR000644 CBS domain LK06_RS00110 8c0cc280b89a5c51a450928b1be55a07 217 SMART SM00116 15 63 0.011 T 06-07-2017 IPR000644 CBS domain LK06_RS00110 8c0cc280b89a5c51a450928b1be55a07 217 Pfam PF00571 CBS domain 90 143 1.1E-13 T 06-07-2017 IPR000644 CBS domain LK06_RS00110 8c0cc280b89a5c51a450928b1be55a07 217 Pfam PF00571 CBS domain 8 59 2.9E-10 T 06-07-2017 IPR000644 CBS domain LK06_RS00110 8c0cc280b89a5c51a450928b1be55a07 217 SUPERFAMILY SSF54631 6 150 4.04E-32 T 06-07-2017 LK06_RS00110 8c0cc280b89a5c51a450928b1be55a07 217 Gene3D G3DSA:3.20.20.70 5 151 3.5E-30 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 SUPERFAMILY SSF54919 3 135 1.28E-52 T 06-07-2017 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 Pfam PF00334 Nucleoside diphosphate kinase 3 135 7.0E-53 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 Gene3D G3DSA:3.30.70.141 3 135 1.9E-56 T 06-07-2017 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 06-07-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 SMART SM00562 2 136 2.0E-76 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 137 32.557 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.9E-42 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.9E-42 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.9E-42 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 1.9E-42 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS09880 92c33a5c00cd9c232fb861d1fb4e7192 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.9E-42 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS02535 3cc73d22e5cd9f9ec76c32d611ae0a1b 550 Pfam PF00732 GMC oxidoreductase 8 258 9.4E-17 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LK06_RS02535 3cc73d22e5cd9f9ec76c32d611ae0a1b 550 Gene3D G3DSA:3.50.50.60 421 515 3.6E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02535 3cc73d22e5cd9f9ec76c32d611ae0a1b 550 Gene3D G3DSA:3.50.50.60 172 278 3.6E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02535 3cc73d22e5cd9f9ec76c32d611ae0a1b 550 Gene3D G3DSA:3.50.50.60 5 124 3.6E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02535 3cc73d22e5cd9f9ec76c32d611ae0a1b 550 SUPERFAMILY SSF51905 454 516 2.11E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02535 3cc73d22e5cd9f9ec76c32d611ae0a1b 550 SUPERFAMILY SSF51905 4 276 2.11E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02535 3cc73d22e5cd9f9ec76c32d611ae0a1b 550 Pfam PF05199 GMC oxidoreductase 452 509 1.7E-14 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LK06_RS09465 3a03a8d402338e3cf2b477330307569b 301 SUPERFAMILY SSF56281 5 296 7.86E-62 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS09465 3a03a8d402338e3cf2b477330307569b 301 Pfam PF12706 Beta-lactamase superfamily domain 34 263 1.7E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS09465 3a03a8d402338e3cf2b477330307569b 301 Hamap MF_01818 Ribonuclease BN [rbn]. 4 297 31.095 T 06-07-2017 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 LK06_RS09465 3a03a8d402338e3cf2b477330307569b 301 Gene3D G3DSA:3.60.15.10 5 300 4.8E-72 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS11930 bfbb79c97872ad46e74239bb8f71c7e3 506 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 334 486 7.4E-15 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS11930 bfbb79c97872ad46e74239bb8f71c7e3 506 SUPERFAMILY SSF55846 311 498 4.06E-52 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS11930 bfbb79c97872ad46e74239bb8f71c7e3 506 Gene3D G3DSA:3.40.80.10 308 502 1.7E-52 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS11930 bfbb79c97872ad46e74239bb8f71c7e3 506 SMART SM00644 325 486 0.0024 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS11930 bfbb79c97872ad46e74239bb8f71c7e3 506 SMART SM00701 311 459 9.0E-58 T 06-07-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 LK06_RS11580 15ddde0c81ce277caa04fcc6a92cbf70 229 SMART SM00382 28 215 9.1E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS11580 15ddde0c81ce277caa04fcc6a92cbf70 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS11580 15ddde0c81ce277caa04fcc6a92cbf70 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 3.7E-86 T 06-07-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 LK06_RS11580 15ddde0c81ce277caa04fcc6a92cbf70 229 Gene3D G3DSA:3.40.50.300 1 219 1.3E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11580 15ddde0c81ce277caa04fcc6a92cbf70 229 Pfam PF00005 ABC transporter 19 166 4.5E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS11580 15ddde0c81ce277caa04fcc6a92cbf70 229 SUPERFAMILY SSF52540 1 220 2.6E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00575 6008d238d566f1474e7323864969cd90 407 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 58 395 1.4E-92 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LK06_RS00575 6008d238d566f1474e7323864969cd90 407 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 6 406 8.8E-137 T 06-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 LK06_RS00575 6008d238d566f1474e7323864969cd90 407 SUPERFAMILY SSF54909 45 399 2.68E-93 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS00575 6008d238d566f1474e7323864969cd90 407 Pfam PF04261 Dyp-type peroxidase family 55 395 2.7E-101 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LK06_RS00055 eac252e8a9ae258a95989a912b55b7a9 273 Pfam PF00005 ABC transporter 47 199 1.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS00055 eac252e8a9ae258a95989a912b55b7a9 273 SUPERFAMILY SSF52540 29 270 2.39E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00055 eac252e8a9ae258a95989a912b55b7a9 273 SMART SM00382 55 250 6.1E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS00055 eac252e8a9ae258a95989a912b55b7a9 273 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 249 270 1.4E-4 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LK06_RS00055 eac252e8a9ae258a95989a912b55b7a9 273 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS00055 eac252e8a9ae258a95989a912b55b7a9 273 Gene3D G3DSA:3.40.50.300 28 266 1.3E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08140 41f13047339a64179693bfdadf84e4a0 453 Pfam PF00120 Glutamine synthetase, catalytic domain 105 448 1.6E-126 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08140 41f13047339a64179693bfdadf84e4a0 453 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 1.1E-28 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08140 41f13047339a64179693bfdadf84e4a0 453 Gene3D G3DSA:3.10.20.70 6 107 2.6E-39 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08140 41f13047339a64179693bfdadf84e4a0 453 SMART SM01230 104 363 1.7E-122 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08140 41f13047339a64179693bfdadf84e4a0 453 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 LK06_RS08140 41f13047339a64179693bfdadf84e4a0 453 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 448 5.2E-131 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08140 41f13047339a64179693bfdadf84e4a0 453 SUPERFAMILY SSF54368 8 103 1.44E-30 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LK06_RS08140 41f13047339a64179693bfdadf84e4a0 453 Gene3D G3DSA:3.30.590.10 108 440 1.5E-112 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LK06_RS08140 41f13047339a64179693bfdadf84e4a0 453 SUPERFAMILY SSF55931 106 450 6.28E-113 T 06-07-2017 LK06_RS15355 c4bb839a4780b585bd3d4e8a22e46ced 446 Gene3D G3DSA:1.20.1250.20 251 426 5.4E-12 T 06-07-2017 LK06_RS15355 c4bb839a4780b585bd3d4e8a22e46ced 446 SUPERFAMILY SSF103473 16 431 5.23E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS15355 c4bb839a4780b585bd3d4e8a22e46ced 446 Gene3D G3DSA:1.20.1250.20 35 217 3.8E-28 T 06-07-2017 LK06_RS15355 c4bb839a4780b585bd3d4e8a22e46ced 446 Pfam PF07690 Major Facilitator Superfamily 40 383 1.0E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS17405 87b09c5ff103e326ca2d5173ef38c9f4 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 2.4E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS17405 87b09c5ff103e326ca2d5173ef38c9f4 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 218 2.4E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS17405 87b09c5ff103e326ca2d5173ef38c9f4 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 2.4E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS17405 87b09c5ff103e326ca2d5173ef38c9f4 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 29 46 2.4E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS17405 87b09c5ff103e326ca2d5173ef38c9f4 315 Gene3D G3DSA:3.40.50.720 25 253 2.2E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS17405 87b09c5ff103e326ca2d5173ef38c9f4 315 Pfam PF00106 short chain dehydrogenase 29 220 1.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS17405 87b09c5ff103e326ca2d5173ef38c9f4 315 SUPERFAMILY SSF51735 25 252 3.06E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28900 5763d229083ca537188eba71d569aee8 178 Pfam PF16262 Domain of unknown function (DUF4916) 8 175 9.6E-85 T 06-07-2017 IPR032582 Protein of unknown function DUF4916 LK06_RS28900 5763d229083ca537188eba71d569aee8 178 SUPERFAMILY SSF55811 29 171 2.4E-7 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS28900 5763d229083ca537188eba71d569aee8 178 Gene3D G3DSA:3.90.79.10 27 171 2.4E-6 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS09545 107644a3f1fed8879dc5a481580a3beb 329 Gene3D G3DSA:1.10.8.60 137 220 6.0E-6 T 06-07-2017 LK06_RS09545 107644a3f1fed8879dc5a481580a3beb 329 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 11 319 2.6E-32 T 06-07-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 LK06_RS09545 107644a3f1fed8879dc5a481580a3beb 329 Pfam PF06144 DNA polymerase III, delta subunit 16 179 1.3E-11 T 06-07-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 LK06_RS09545 107644a3f1fed8879dc5a481580a3beb 329 Gene3D G3DSA:3.40.50.300 11 105 2.4E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09545 107644a3f1fed8879dc5a481580a3beb 329 SUPERFAMILY SSF48019 203 321 3.57E-14 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 LK06_RS09545 107644a3f1fed8879dc5a481580a3beb 329 SUPERFAMILY SSF52540 9 184 1.33E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 Gene3D G3DSA:3.30.70.1400 60 144 2.7E-28 T 06-07-2017 LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 Gene3D G3DSA:2.40.30.110 293 367 1.0E-27 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 PIRSF PIRSF006487 1 375 5.6E-99 T 06-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 Gene3D G3DSA:3.30.1360.120 148 242 2.5E-53 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 Gene3D G3DSA:3.30.1360.120 10 59 2.5E-53 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 10 373 6.0E-106 T 06-07-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 SUPERFAMILY SSF101790 287 374 1.32E-23 T 06-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 272 367 6.2E-24 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 Pfam PF01571 Aminomethyltransferase folate-binding domain 15 264 1.2E-90 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 SUPERFAMILY SSF103025 8 285 3.77E-97 T 06-07-2017 LK06_RS23750 bbc15abdb9d0650a7d43d892a0249c83 375 Hamap MF_00259 Aminomethyltransferase [gcvT]. 8 373 44.643 T 06-07-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 LK06_RS20205 e19de03f7a259bc559713548e42c3255 308 SUPERFAMILY SSF56112 11 263 2.97E-47 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS20205 e19de03f7a259bc559713548e42c3255 308 Gene3D G3DSA:1.10.510.10 90 204 1.5E-27 T 06-07-2017 LK06_RS20205 e19de03f7a259bc559713548e42c3255 308 Pfam PF00069 Protein kinase domain 19 205 3.4E-29 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20205 e19de03f7a259bc559713548e42c3255 308 SMART SM00220 18 246 4.9E-23 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20205 e19de03f7a259bc559713548e42c3255 308 Gene3D G3DSA:3.30.200.20 10 89 3.2E-17 T 06-07-2017 LK06_RS20205 e19de03f7a259bc559713548e42c3255 308 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 141 153 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS27635 682c788b9773846372d226d8ae4de0b7 464 Gene3D G3DSA:3.30.1330.120 262 401 4.1E-28 T 06-07-2017 LK06_RS27635 682c788b9773846372d226d8ae4de0b7 464 Pfam PF03972 MmgE/PrpD family 7 435 5.3E-75 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 LK06_RS27635 682c788b9773846372d226d8ae4de0b7 464 SUPERFAMILY SSF103378 6 441 1.7E-75 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 LK06_RS21220 34434ca7d9c383c05c99be53992c4285 136 Pfam PF01042 Endoribonuclease L-PSP 15 134 1.4E-23 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family LK06_RS21220 34434ca7d9c383c05c99be53992c4285 136 Gene3D G3DSA:3.30.1330.40 2 135 1.1E-33 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS21220 34434ca7d9c383c05c99be53992c4285 136 SUPERFAMILY SSF55298 4 136 1.73E-30 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS28055 8fe161f3fd99863ab0f215483d605a81 307 PIRSF PIRSF028757 4 305 1.5E-70 T 06-07-2017 IPR003507 Peptidase family S66 LK06_RS28055 8fe161f3fd99863ab0f215483d605a81 307 SUPERFAMILY SSF141986 151 298 1.44E-37 T 06-07-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain LK06_RS28055 8fe161f3fd99863ab0f215483d605a81 307 Gene3D G3DSA:3.40.50.10740 4 166 2.8E-51 T 06-07-2017 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain LK06_RS28055 8fe161f3fd99863ab0f215483d605a81 307 Pfam PF02016 LD-carboxypeptidase 16 292 8.4E-73 T 06-07-2017 IPR003507 Peptidase family S66 LK06_RS28055 8fe161f3fd99863ab0f215483d605a81 307 SUPERFAMILY SSF52317 4 166 5.49E-46 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS28055 8fe161f3fd99863ab0f215483d605a81 307 Gene3D G3DSA:3.50.30.60 173 300 1.2E-35 T 06-07-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain LK06_RS16115 abbef022e2df83948dec34264e337efb 359 Pfam PF00149 Calcineurin-like phosphoesterase 90 306 9.8E-11 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 LK06_RS16115 abbef022e2df83948dec34264e337efb 359 PRINTS PR00114 Serine/threonine phosphatase family signature 127 154 1.5E-6 T 06-07-2017 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 LK06_RS16115 abbef022e2df83948dec34264e337efb 359 PRINTS PR00114 Serine/threonine phosphatase family signature 90 117 1.5E-6 T 06-07-2017 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 LK06_RS16115 abbef022e2df83948dec34264e337efb 359 SUPERFAMILY SSF56300 83 346 3.63E-37 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS16115 abbef022e2df83948dec34264e337efb 359 Gene3D G3DSA:3.60.21.10 82 351 5.3E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS20385 b1c5c1dfb22595a29fcf3f7b71d9595a 144 Pfam PF11222 Protein of unknown function (DUF3017) 52 121 7.2E-22 T 06-07-2017 IPR021385 Protein of unknown function DUF3017 LK06_RS02290 a8dc12393af1a52cac830c85b46e78df 253 Hamap MF_01384 Urease accessory protein UreD [ureD]. 6 252 19.365 T 06-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 LK06_RS02290 a8dc12393af1a52cac830c85b46e78df 253 Pfam PF01774 UreD urease accessory protein 47 241 1.4E-26 T 06-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 LK06_RS18600 a7716be228bf05c73839dbc398f96bb1 332 Gene3D G3DSA:2.130.10.10 41 271 1.7E-10 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS18600 a7716be228bf05c73839dbc398f96bb1 332 SUPERFAMILY SSF75011 50 283 1.57E-16 T 06-07-2017 LK06_RS26385 647f9426519c4ac75d35598f4d4cc771 180 SUPERFAMILY SSF55961 12 135 5.96E-17 T 06-07-2017 LK06_RS26385 647f9426519c4ac75d35598f4d4cc771 180 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 13 174 5.7E-15 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase LK06_RS26385 647f9426519c4ac75d35598f4d4cc771 180 Gene3D G3DSA:3.30.530.20 12 135 1.1E-12 T 06-07-2017 IPR023393 START-like domain LK06_RS24285 18489006c53d43edf126306175b0c506 217 Pfam PF02620 Uncharacterized ACR, COG1399 69 189 1.6E-32 T 06-07-2017 IPR003772 Protein of unknown function DUF177 LK06_RS20545 eb13853a8d85c9a5e9b821d5502d8273 160 SUPERFAMILY SSF81343 35 157 5.67E-34 T 06-07-2017 LK06_RS20545 eb13853a8d85c9a5e9b821d5502d8273 160 Gene3D G3DSA:1.20.950.10 32 159 5.5E-39 T 06-07-2017 LK06_RS20545 eb13853a8d85c9a5e9b821d5502d8273 160 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 36 146 6.1E-18 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 222 232 1.1E-12 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 1.1E-12 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 1.1E-12 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 1.1E-12 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 118 132 1.1E-12 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 140 3.8E-32 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 149 301 1.2E-36 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 Gene3D G3DSA:3.40.50.1370 2 138 9.1E-36 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 3.7E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 3.7E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 129 140 3.7E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 3.7E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 SUPERFAMILY SSF53671 2 305 3.4E-74 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS21030 9bcbe4fb231c796d34533905d9481e3a 308 Gene3D G3DSA:3.40.50.1370 139 290 1.4E-42 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LK06_RS26820 08d3dec7bb4698b1d5d30ebab4638bee 215 Gene3D G3DSA:1.10.357.10 2 193 1.2E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS26820 08d3dec7bb4698b1d5d30ebab4638bee 215 SUPERFAMILY SSF48498 81 206 1.13E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS26820 08d3dec7bb4698b1d5d30ebab4638bee 215 SUPERFAMILY SSF46689 2 78 4.62E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS26820 08d3dec7bb4698b1d5d30ebab4638bee 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS26820 08d3dec7bb4698b1d5d30ebab4638bee 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 5.4E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS26820 08d3dec7bb4698b1d5d30ebab4638bee 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 5.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS26820 08d3dec7bb4698b1d5d30ebab4638bee 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 5.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS20420 97898572dd9802c885298c55297afd1e 369 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 61 308 4.2E-107 T 06-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 LK06_RS20420 97898572dd9802c885298c55297afd1e 369 Gene3D G3DSA:3.40.50.300 62 289 6.1E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20420 97898572dd9802c885298c55297afd1e 369 SMART SM00382 77 274 4.0E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS20420 97898572dd9802c885298c55297afd1e 369 Pfam PF00005 ABC transporter 69 216 6.9E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS20420 97898572dd9802c885298c55297afd1e 369 SUPERFAMILY SSF52540 64 293 2.66E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20420 97898572dd9802c885298c55297afd1e 369 ProSitePatterns PS00211 ABC transporters family signature. 189 203 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS27415 2bbe75ecf453dce33399c1554f45c90a 461 SUPERFAMILY SSF51556 66 381 8.32E-93 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS27415 2bbe75ecf453dce33399c1554f45c90a 461 Gene3D G3DSA:3.20.20.140 69 389 7.2E-104 T 06-07-2017 LK06_RS27415 2bbe75ecf453dce33399c1554f45c90a 461 SUPERFAMILY SSF51338 8 79 9.12E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS27415 2bbe75ecf453dce33399c1554f45c90a 461 Gene3D G3DSA:2.30.40.10 390 428 4.2E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS27415 2bbe75ecf453dce33399c1554f45c90a 461 Gene3D G3DSA:2.30.40.10 5 68 4.2E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS27415 2bbe75ecf453dce33399c1554f45c90a 461 SUPERFAMILY SSF51338 341 456 6.59E-29 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS27415 2bbe75ecf453dce33399c1554f45c90a 461 Pfam PF01979 Amidohydrolase family 64 427 1.3E-61 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS24710 982a3943163f5961f91e2288aac3d0d0 385 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 6.2E-131 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS24710 982a3943163f5961f91e2288aac3d0d0 385 Gene3D G3DSA:3.20.20.70 46 212 7.5E-5 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS24710 982a3943163f5961f91e2288aac3d0d0 385 SUPERFAMILY SSF51717 45 220 1.02E-9 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS24710 982a3943163f5961f91e2288aac3d0d0 385 PIRSF PIRSF004640 11 372 1.6E-147 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS24710 982a3943163f5961f91e2288aac3d0d0 385 Pfam PF04551 GcpE protein 22 361 3.7E-135 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS24710 982a3943163f5961f91e2288aac3d0d0 385 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.828 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LK06_RS24710 982a3943163f5961f91e2288aac3d0d0 385 SUPERFAMILY SSF56014 277 359 3.88E-11 T 06-07-2017 LK06_RS24410 479f39f31d9e6bd1f7db1fab7aa153da 139 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.0E-31 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24410 479f39f31d9e6bd1f7db1fab7aa153da 139 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 06-07-2017 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24410 479f39f31d9e6bd1f7db1fab7aa153da 139 Pfam PF00886 Ribosomal protein S16 9 67 4.6E-23 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24410 479f39f31d9e6bd1f7db1fab7aa153da 139 Gene3D G3DSA:3.30.1320.10 2 83 6.1E-32 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24410 479f39f31d9e6bd1f7db1fab7aa153da 139 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.855 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24410 479f39f31d9e6bd1f7db1fab7aa153da 139 SUPERFAMILY SSF54565 2 88 4.32E-33 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09070 91e86552038a2df24e97ef705544f351 270 SUPERFAMILY SSF56112 32 216 9.33E-15 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS09070 91e86552038a2df24e97ef705544f351 270 Pfam PF01636 Phosphotransferase enzyme family 152 214 6.6E-7 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS09070 91e86552038a2df24e97ef705544f351 270 Gene3D G3DSA:3.90.1200.10 38 75 8.3E-9 T 06-07-2017 LK06_RS09070 91e86552038a2df24e97ef705544f351 270 Gene3D G3DSA:3.90.1200.10 128 227 8.3E-9 T 06-07-2017 LK06_RS31475 b53d6f6e79a273abd347fc9368ec3d26 282 SUPERFAMILY SSF140959 26 280 3.79E-78 T 06-07-2017 LK06_RS31475 b53d6f6e79a273abd347fc9368ec3d26 282 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 20 282 35.32 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 LK06_RS31475 b53d6f6e79a273abd347fc9368ec3d26 282 Pfam PF03301 Tryptophan 2,3-dioxygenase 22 224 2.8E-42 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 LK06_RS00930 99af56477b10a0783b3c03cd2792729d 362 Gene3D G3DSA:3.90.180.10 3 183 3.5E-53 T 06-07-2017 IPR011032 GroES-like LK06_RS00930 99af56477b10a0783b3c03cd2792729d 362 Gene3D G3DSA:3.40.50.720 184 303 6.7E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00930 99af56477b10a0783b3c03cd2792729d 362 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 362 9.9E-209 T 06-07-2017 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 LK06_RS00930 99af56477b10a0783b3c03cd2792729d 362 SMART SM00829 12 362 3.8E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS00930 99af56477b10a0783b3c03cd2792729d 362 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LK06_RS00930 99af56477b10a0783b3c03cd2792729d 362 SUPERFAMILY SSF50129 4 187 3.04E-53 T 06-07-2017 IPR011032 GroES-like LK06_RS00930 99af56477b10a0783b3c03cd2792729d 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 149 3.3E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS00930 99af56477b10a0783b3c03cd2792729d 362 SUPERFAMILY SSF51735 153 327 7.12E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00930 99af56477b10a0783b3c03cd2792729d 362 SUPERFAMILY SSF50129 311 361 2.45E-8 T 06-07-2017 IPR011032 GroES-like LK06_RS00930 99af56477b10a0783b3c03cd2792729d 362 Pfam PF00107 Zinc-binding dehydrogenase 191 317 9.0E-32 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS01585 68b7edcb8ad68ded20bf405cc368251e 249 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 119 1.1E-24 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS01585 68b7edcb8ad68ded20bf405cc368251e 249 SUPERFAMILY SSF46548 118 241 1.05E-24 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 LK06_RS01585 68b7edcb8ad68ded20bf405cc368251e 249 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 158 169 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS01585 68b7edcb8ad68ded20bf405cc368251e 249 Pfam PF12838 4Fe-4S dicluster domain 158 227 1.6E-10 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LK06_RS01585 68b7edcb8ad68ded20bf405cc368251e 249 SUPERFAMILY SSF54292 1 115 6.1E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS01585 68b7edcb8ad68ded20bf405cc368251e 249 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LK06_RS01585 68b7edcb8ad68ded20bf405cc368251e 249 Gene3D G3DSA:1.10.1060.10 111 242 2.0E-20 T 06-07-2017 LK06_RS01585 68b7edcb8ad68ded20bf405cc368251e 249 Gene3D G3DSA:3.10.20.30 1 110 3.9E-29 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS18370 e2a20d11629a61ba62d946c7fc02ade1 363 Pfam PF13560 Helix-turn-helix domain 46 96 1.6E-7 T 06-07-2017 LK06_RS18370 e2a20d11629a61ba62d946c7fc02ade1 363 Pfam PF10901 Protein of unknown function (DUF2690) 255 342 2.1E-14 T 06-07-2017 IPR021224 Protein of unknown function DUF2690 LK06_RS04125 fdce99e17cf752397a3bf27eece3f0c3 428 Gene3D G3DSA:2.30.40.10 3 65 1.1E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS04125 fdce99e17cf752397a3bf27eece3f0c3 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 424 7.2E-128 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 LK06_RS04125 fdce99e17cf752397a3bf27eece3f0c3 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 LK06_RS04125 fdce99e17cf752397a3bf27eece3f0c3 428 SUPERFAMILY SSF51556 51 360 1.51E-100 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS04125 fdce99e17cf752397a3bf27eece3f0c3 428 Gene3D G3DSA:3.20.20.140 66 407 1.1E-103 T 06-07-2017 LK06_RS04125 fdce99e17cf752397a3bf27eece3f0c3 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 425 43.3 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 LK06_RS04125 fdce99e17cf752397a3bf27eece3f0c3 428 SUPERFAMILY SSF51338 367 427 3.17E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS04125 fdce99e17cf752397a3bf27eece3f0c3 428 SUPERFAMILY SSF51338 1 50 3.17E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS04125 fdce99e17cf752397a3bf27eece3f0c3 428 Pfam PF01979 Amidohydrolase family 47 420 1.3E-18 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS10455 69295e2b5fdaa40ace31acd99dbde85e 309 SUPERFAMILY SSF51569 40 303 1.43E-37 T 06-07-2017 LK06_RS10455 69295e2b5fdaa40ace31acd99dbde85e 309 Gene3D G3DSA:3.20.20.70 37 304 7.3E-39 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS11020 9ec384baae19861e985ea5934e6b2fe9 257 Gene3D G3DSA:3.40.1410.10 85 249 2.5E-42 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS11020 9ec384baae19861e985ea5934e6b2fe9 257 Pfam PF07702 UTRA domain 106 243 2.3E-30 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS11020 9ec384baae19861e985ea5934e6b2fe9 257 SUPERFAMILY SSF46785 20 90 2.41E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11020 9ec384baae19861e985ea5934e6b2fe9 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 85 3.4E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS11020 9ec384baae19861e985ea5934e6b2fe9 257 Gene3D G3DSA:1.10.10.10 20 84 6.8E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11020 9ec384baae19861e985ea5934e6b2fe9 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 1.8E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS11020 9ec384baae19861e985ea5934e6b2fe9 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 1.8E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS11020 9ec384baae19861e985ea5934e6b2fe9 257 SMART SM00345 29 85 3.4E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS11020 9ec384baae19861e985ea5934e6b2fe9 257 SMART SM00866 105 244 2.0E-31 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS11020 9ec384baae19861e985ea5934e6b2fe9 257 SUPERFAMILY SSF64288 77 249 5.18E-44 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS18540 0e255a753d1c1691fd63c3c7eb37557b 587 Gene3D G3DSA:2.130.10.10 184 375 1.6E-11 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS18540 0e255a753d1c1691fd63c3c7eb37557b 587 Gene3D G3DSA:2.130.10.10 56 126 1.6E-11 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS18540 0e255a753d1c1691fd63c3c7eb37557b 587 SUPERFAMILY SSF75011 217 383 1.24E-16 T 06-07-2017 LK06_RS18540 0e255a753d1c1691fd63c3c7eb37557b 587 SUPERFAMILY SSF75011 55 134 1.24E-16 T 06-07-2017 LK06_RS22885 09d98f85ddbea52ddc29c1d32368e4f4 137 Gene3D G3DSA:3.40.50.1010 13 135 2.1E-4 T 06-07-2017 IPR029060 PIN domain-like LK06_RS22885 09d98f85ddbea52ddc29c1d32368e4f4 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 12 132 9.507 T 06-07-2017 IPR022907 VapC family GO:0004540 LK06_RS22885 09d98f85ddbea52ddc29c1d32368e4f4 137 Pfam PF01850 PIN domain 36 122 4.9E-6 T 06-07-2017 IPR002716 PIN domain LK06_RS22885 09d98f85ddbea52ddc29c1d32368e4f4 137 SUPERFAMILY SSF88723 13 130 3.11E-12 T 06-07-2017 IPR029060 PIN domain-like LK06_RS19685 eb47ea622bdc89cc4cde64d4e3988fbc 576 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 381 575 5.0E-24 T 06-07-2017 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 LK06_RS19685 eb47ea622bdc89cc4cde64d4e3988fbc 576 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 77 306 2.6E-20 T 06-07-2017 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 LK06_RS09265 afa67ca3a3f2485e30cb52845fe34038 538 Gene3D G3DSA:3.40.720.10 295 470 1.2E-4 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 LK06_RS09265 afa67ca3a3f2485e30cb52845fe34038 538 SUPERFAMILY SSF53649 434 478 8.07E-8 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 LK06_RS09265 afa67ca3a3f2485e30cb52845fe34038 538 SUPERFAMILY SSF53649 255 406 8.07E-8 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 LK06_RS30230 8428163537834774b8d6a277d2bb2795 205 SUPERFAMILY SSF54631 1 119 2.4E-33 T 06-07-2017 LK06_RS30230 8428163537834774b8d6a277d2bb2795 205 SMART SM00116 72 120 1.4E-15 T 06-07-2017 IPR000644 CBS domain LK06_RS30230 8428163537834774b8d6a277d2bb2795 205 SMART SM00116 4 52 1.2E-7 T 06-07-2017 IPR000644 CBS domain LK06_RS30230 8428163537834774b8d6a277d2bb2795 205 Gene3D G3DSA:3.20.20.70 1 128 8.6E-35 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS30230 8428163537834774b8d6a277d2bb2795 205 PIRSF PIRSF036990 1 203 5.8E-58 T 06-07-2017 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON LK06_RS30230 8428163537834774b8d6a277d2bb2795 205 Pfam PF00571 CBS domain 1 51 1.1E-9 T 06-07-2017 IPR000644 CBS domain LK06_RS30230 8428163537834774b8d6a277d2bb2795 205 Pfam PF00571 CBS domain 65 119 2.8E-18 T 06-07-2017 IPR000644 CBS domain LK06_RS30230 8428163537834774b8d6a277d2bb2795 205 Pfam PF04972 BON domain 123 189 3.6E-9 T 06-07-2017 IPR007055 BON domain LK06_RS30030 63cf179844ba076725cbd51278891c4b 376 Pfam PF05175 Methyltransferase small domain 204 372 2.9E-55 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 LK06_RS30030 63cf179844ba076725cbd51278891c4b 376 Gene3D G3DSA:3.40.50.150 200 375 1.2E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS30030 63cf179844ba076725cbd51278891c4b 376 SUPERFAMILY SSF53335 188 350 4.76E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS30030 63cf179844ba076725cbd51278891c4b 376 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 304 310 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LK06_RS30030 63cf179844ba076725cbd51278891c4b 376 PIRSF PIRSF037565 1 376 6.0E-139 T 06-07-2017 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS30030 63cf179844ba076725cbd51278891c4b 376 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 2 375 44.805 T 06-07-2017 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 SUPERFAMILY SSF100950 84 145 1.26E-30 T 06-07-2017 LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 SUPERFAMILY SSF100950 174 250 1.26E-30 T 06-07-2017 LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 Pfam PF08220 DeoR-like helix-turn-helix domain 12 63 4.0E-17 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 Pfam PF00455 DeoR C terminal sensor domain 83 246 3.0E-52 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 SMART SM00420 12 64 9.2E-18 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 Gene3D G3DSA:3.40.50.1360 88 228 2.3E-15 T 06-07-2017 LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 SUPERFAMILY SSF46785 10 65 7.58E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 Gene3D G3DSA:1.10.10.10 11 87 1.0E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 44 9.1E-10 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 62 9.1E-10 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 LK06_RS30085 8cc08e9ec152d407f8ff2f5b84d0e218 276 SMART SM01134 80 248 7.3E-63 T 06-07-2017 LK06_RS15075 99fab7babe992c058607a179b10df28b 183 Gene3D G3DSA:1.10.1740.10 13 86 5.7E-17 T 06-07-2017 LK06_RS15075 99fab7babe992c058607a179b10df28b 183 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 12 167 1.5E-47 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 LK06_RS15075 99fab7babe992c058607a179b10df28b 183 SUPERFAMILY SSF88659 108 165 3.18E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15075 99fab7babe992c058607a179b10df28b 183 Pfam PF08281 Sigma-70, region 4 110 161 2.6E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15075 99fab7babe992c058607a179b10df28b 183 Pfam PF04542 Sigma-70 region 2 21 85 2.2E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15075 99fab7babe992c058607a179b10df28b 183 SUPERFAMILY SSF88946 13 96 1.02E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15075 99fab7babe992c058607a179b10df28b 183 Gene3D G3DSA:1.10.10.10 110 167 1.8E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04050 8e4fc7d0dc0b641a53f140e6aa382cbf 228 Gene3D G3DSA:3.20.20.70 3 219 3.4E-93 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS04050 8e4fc7d0dc0b641a53f140e6aa382cbf 228 PIRSF PIRSF001461 1 224 2.6E-97 T 06-07-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 LK06_RS04050 8e4fc7d0dc0b641a53f140e6aa382cbf 228 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 30 44 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 LK06_RS04050 8e4fc7d0dc0b641a53f140e6aa382cbf 228 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 199 5.1E-79 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 LK06_RS04050 8e4fc7d0dc0b641a53f140e6aa382cbf 228 SUPERFAMILY SSF51366 3 212 7.07E-65 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 LK06_RS04050 8e4fc7d0dc0b641a53f140e6aa382cbf 228 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 212 2.1E-82 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 LK06_RS04050 8e4fc7d0dc0b641a53f140e6aa382cbf 228 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 132 154 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 LK06_RS12070 aeffa8185488bb33e9606a57fcc1a733 524 Gene3D G3DSA:2.80.10.50 393 520 5.6E-15 T 06-07-2017 LK06_RS12070 aeffa8185488bb33e9606a57fcc1a733 524 SMART SM00458 393 522 5.8E-12 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS12070 aeffa8185488bb33e9606a57fcc1a733 524 Pfam PF00652 Ricin-type beta-trefoil lectin domain 396 519 4.8E-14 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS12070 aeffa8185488bb33e9606a57fcc1a733 524 SUPERFAMILY SSF50370 391 520 3.31E-17 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS08085 540b7db2ef74479e127a884d5fa0a338 121 Gene3D G3DSA:3.30.429.10 2 116 8.5E-16 T 06-07-2017 LK06_RS08085 540b7db2ef74479e127a884d5fa0a338 121 SUPERFAMILY SSF55331 2 116 9.99E-15 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily LK06_RS10985 33ea816ac7cffcff41b7a4b1985cdb18 433 Gene3D G3DSA:1.10.101.10 267 332 1.2E-5 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS10985 33ea816ac7cffcff41b7a4b1985cdb18 433 Gene3D G3DSA:1.10.101.10 364 431 7.4E-9 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS10985 33ea816ac7cffcff41b7a4b1985cdb18 433 SUPERFAMILY SSF47090 262 332 8.63E-6 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS10985 33ea816ac7cffcff41b7a4b1985cdb18 433 SUPERFAMILY SSF47090 359 432 1.06E-9 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS10985 33ea816ac7cffcff41b7a4b1985cdb18 433 Pfam PF00877 NlpC/P60 family 138 210 2.2E-4 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS10985 33ea816ac7cffcff41b7a4b1985cdb18 433 Gene3D G3DSA:3.90.1720.10 107 208 2.4E-13 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS10985 33ea816ac7cffcff41b7a4b1985cdb18 433 SUPERFAMILY SSF54001 102 209 9.48E-11 T 06-07-2017 LK06_RS29490 b627cb470f5f081c66d6494e6f567ccb 184 Pfam PF04314 Protein of unknown function (DUF461) 68 171 1.7E-30 T 06-07-2017 IPR007410 DR1885-like metal-binding protein LK06_RS29490 b627cb470f5f081c66d6494e6f567ccb 184 SUPERFAMILY SSF110087 65 177 5.75E-35 T 06-07-2017 IPR007410 DR1885-like metal-binding protein LK06_RS25530 5e0df7f08d157641ed77d9d8f0622fa1 1060 Pfam PF13032 Domain of unknown function (DUF3893) 885 1029 6.5E-5 T 06-07-2017 IPR024996 Domain of unknown function DUF3893 LK06_RS13925 2bf5c5e5b145a3736b690898007bd3fe 118 SMART SM00418 37 112 2.9E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13925 2bf5c5e5b145a3736b690898007bd3fe 118 Pfam PF12840 Helix-turn-helix domain 36 96 4.5E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13925 2bf5c5e5b145a3736b690898007bd3fe 118 SUPERFAMILY SSF46785 31 113 1.43E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13925 2bf5c5e5b145a3736b690898007bd3fe 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 4.2E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13925 2bf5c5e5b145a3736b690898007bd3fe 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 4.2E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13925 2bf5c5e5b145a3736b690898007bd3fe 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 4.2E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13925 2bf5c5e5b145a3736b690898007bd3fe 118 Gene3D G3DSA:1.10.10.10 24 112 1.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06325 5d3fd1692d9c6a4424c39d379e0ddb51 172 SUPERFAMILY SSF55729 12 161 1.61E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS06325 5d3fd1692d9c6a4424c39d379e0ddb51 172 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 10 166 1.6E-61 T 06-07-2017 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 LK06_RS06325 5d3fd1692d9c6a4424c39d379e0ddb51 172 Pfam PF00583 Acetyltransferase (GNAT) family 57 132 2.2E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS06325 5d3fd1692d9c6a4424c39d379e0ddb51 172 Gene3D G3DSA:3.40.630.30 8 168 1.2E-66 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS19380 00a971d7d0a3e39836ee82cc90313873 159 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 7 153 6.6E-63 T 06-07-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 LK06_RS19380 00a971d7d0a3e39836ee82cc90313873 159 SUPERFAMILY SSF55040 14 156 6.28E-57 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 LK06_RS19380 00a971d7d0a3e39836ee82cc90313873 159 Gene3D G3DSA:3.30.70.640 7 158 2.4E-64 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 LK06_RS19380 00a971d7d0a3e39836ee82cc90313873 159 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 5 159 36.168 T 06-07-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 LK06_RS19380 00a971d7d0a3e39836ee82cc90313873 159 Pfam PF01967 MoaC family 18 151 2.6E-52 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 LK06_RS18935 89b91168848b1db9151dc156459c366b 790 Gene3D G3DSA:2.140.10.10 418 443 2.1E-59 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS18935 89b91168848b1db9151dc156459c366b 790 Gene3D G3DSA:2.140.10.10 477 785 2.1E-59 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS18935 89b91168848b1db9151dc156459c366b 790 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 44 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS18935 89b91168848b1db9151dc156459c366b 790 Pfam PF00069 Protein kinase domain 16 261 6.9E-37 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SUPERFAMILY SSF56112 12 290 3.51E-61 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS18935 89b91168848b1db9151dc156459c366b 790 Pfam PF01011 PQQ enzyme repeat 554 584 3.7E-5 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SMART SM00220 16 270 6.6E-39 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS18935 89b91168848b1db9151dc156459c366b 790 Gene3D G3DSA:3.30.200.20 8 82 1.3E-12 T 06-07-2017 LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SMART SM00564 679 710 8.1 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SMART SM00564 466 497 110.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SMART SM00564 719 750 8.2 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SMART SM00564 504 536 42.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SMART SM00564 639 670 1.5E-5 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SMART SM00564 758 790 2.3E-4 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SMART SM00564 432 461 22.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SMART SM00564 548 579 1.6E-4 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SMART SM00564 594 624 70.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SUPERFAMILY SSF50998 414 444 4.45E-19 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SUPERFAMILY SSF50998 478 626 4.45E-19 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS18935 89b91168848b1db9151dc156459c366b 790 SUPERFAMILY SSF50998 597 783 1.02E-31 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS18935 89b91168848b1db9151dc156459c366b 790 Gene3D G3DSA:1.10.510.10 99 262 4.2E-39 T 06-07-2017 LK06_RS18935 89b91168848b1db9151dc156459c366b 790 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS18935 89b91168848b1db9151dc156459c366b 790 Pfam PF13360 PQQ-like domain 608 784 3.6E-25 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 SUPERFAMILY SSF48452 432 549 1.08E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 SMART SM00028 478 511 12.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 SMART SM00028 646 679 90.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 SMART SM00028 520 553 46.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 SMART SM00028 562 595 64.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 SMART SM00028 604 637 90.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 SMART SM00028 688 721 56.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 SUPERFAMILY SSF52540 55 279 1.97E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 SUPERFAMILY SSF48452 557 674 3.21E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 SUPERFAMILY SSF48452 640 741 5.38E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 Gene3D G3DSA:1.25.40.10 437 741 3.3E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 Pfam PF13374 Tetratricopeptide repeat 443 475 0.0056 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 Pfam PF13424 Tetratricopeptide repeat 563 636 1.5E-11 T 06-07-2017 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 Pfam PF13424 Tetratricopeptide repeat 646 720 8.0E-14 T 06-07-2017 LK06_RS16590 e5785f9b763b3d474212f0bcf1caaade 763 Pfam PF13424 Tetratricopeptide repeat 482 551 6.2E-14 T 06-07-2017 LK06_RS30520 71a785a66ebc7d3a34a17271c2fabc97 312 Pfam PF00753 Metallo-beta-lactamase superfamily 69 281 1.4E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS30520 71a785a66ebc7d3a34a17271c2fabc97 312 Gene3D G3DSA:3.60.15.10 51 293 8.1E-48 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS30520 71a785a66ebc7d3a34a17271c2fabc97 312 SUPERFAMILY SSF56281 64 292 2.62E-36 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS30520 71a785a66ebc7d3a34a17271c2fabc97 312 SMART SM00849 69 281 2.5E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS00845 598cc9aa52ed83255b217034ef99739d 676 Pfam PF03239 Iron permease FTR1 family 6 258 6.1E-45 T 06-07-2017 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 LK06_RS00845 598cc9aa52ed83255b217034ef99739d 676 Pfam PF09375 Imelysin 434 543 1.4E-9 T 06-07-2017 LK06_RS18065 6e270cd7bd4e7cdbe86a8391c3711e68 107 Pfam PF13276 HTH-like domain 4 48 3.8E-13 T 06-07-2017 IPR025948 HTH-like domain LK06_RS22545 1e070c025f2cdb8cbdda7114ea179603 209 Pfam PF11706 CGNR zinc finger 141 183 1.0E-15 T 06-07-2017 IPR021005 Zinc finger, CGNR LK06_RS22545 1e070c025f2cdb8cbdda7114ea179603 209 Gene3D G3DSA:1.10.3300.10 8 184 3.1E-47 T 06-07-2017 IPR023286 ABATE domain LK06_RS22545 1e070c025f2cdb8cbdda7114ea179603 209 SUPERFAMILY SSF160904 8 182 6.41E-39 T 06-07-2017 LK06_RS22545 1e070c025f2cdb8cbdda7114ea179603 209 Pfam PF07336 Putative stress-induced transcription regulator 9 134 1.9E-16 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator LK06_RS24740 a469e758209cd7bfabbdcf6c5f970b08 163 Gene3D G3DSA:1.20.1260.10 7 133 5.0E-44 T 06-07-2017 IPR012347 Ferritin-related LK06_RS24740 a469e758209cd7bfabbdcf6c5f970b08 163 Pfam PF14530 Domain of unknown function (DUF4439) 12 142 1.8E-44 T 06-07-2017 IPR029447 Domain of unknown function DUF4439 LK06_RS24740 a469e758209cd7bfabbdcf6c5f970b08 163 SUPERFAMILY SSF47240 6 142 4.3E-37 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 SUPERFAMILY SSF48452 38 260 2.72E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 SUPERFAMILY SSF48452 205 295 3.64E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 SUPERFAMILY SSF48452 340 410 3.64E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 Pfam PF13432 Tetratricopeptide repeat 177 233 2.1E-4 T 06-07-2017 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 Pfam PF13432 Tetratricopeptide repeat 105 163 0.015 T 06-07-2017 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 Pfam PF13432 Tetratricopeptide repeat 349 408 0.0092 T 06-07-2017 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 SMART SM00028 97 130 77.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 SMART SM00028 63 96 400.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 SMART SM00028 376 409 32.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 SMART SM00028 201 234 0.28 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 Gene3D G3DSA:1.25.40.10 34 294 4.1E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05425 718aecf2762ab743acec8126c014ddc5 425 Gene3D G3DSA:1.25.40.10 307 408 9.6E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS32360 f7cd25d05087c16d36f34e942c2156e9 670 Gene3D G3DSA:1.10.260.40 24 73 1.8E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS32360 f7cd25d05087c16d36f34e942c2156e9 670 Pfam PF13560 Helix-turn-helix domain 23 73 4.8E-7 T 06-07-2017 LK06_RS32360 f7cd25d05087c16d36f34e942c2156e9 670 SUPERFAMILY SSF47413 22 73 6.52E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS32360 f7cd25d05087c16d36f34e942c2156e9 670 SMART SM00530 27 80 1.4E-4 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS07830 c460d6725fd7855cf1d5947568e11a7a 323 SMART SM00701 89 239 6.4E-53 T 06-07-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 LK06_RS07830 c460d6725fd7855cf1d5947568e11a7a 323 SUPERFAMILY SSF55846 89 280 1.87E-43 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS07830 c460d6725fd7855cf1d5947568e11a7a 323 Gene3D G3DSA:3.40.80.10 84 285 9.5E-46 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS07830 c460d6725fd7855cf1d5947568e11a7a 323 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 115 267 3.5E-11 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS14515 7493a32720db8cc04794c46721084576 678 Pfam PF00069 Protein kinase domain 15 269 5.7E-41 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS14515 7493a32720db8cc04794c46721084576 678 Gene3D G3DSA:1.10.510.10 71 269 4.8E-42 T 06-07-2017 LK06_RS14515 7493a32720db8cc04794c46721084576 678 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS14515 7493a32720db8cc04794c46721084576 678 Gene3D G3DSA:3.30.200.20 10 70 8.2E-15 T 06-07-2017 LK06_RS14515 7493a32720db8cc04794c46721084576 678 SMART SM00220 15 277 1.1E-43 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS14515 7493a32720db8cc04794c46721084576 678 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS14515 7493a32720db8cc04794c46721084576 678 SUPERFAMILY SSF56112 12 270 6.47E-61 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 Pfam PF13473 Cupredoxin-like domain 16 122 6.7E-17 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 Gene3D G3DSA:2.70.150.10 256 423 5.6E-34 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 Gene3D G3DSA:3.40.1110.10 539 650 3.0E-25 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 Gene3D G3DSA:3.40.50.1000 651 791 1.7E-54 T 06-07-2017 IPR023214 HAD-like domain LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 Gene3D G3DSA:3.40.50.1000 495 538 1.7E-54 T 06-07-2017 IPR023214 HAD-like domain LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 Pfam PF04945 YHS domain 873 915 2.8E-7 T 06-07-2017 IPR007029 YHS domain LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 Pfam PF00702 haloacid dehalogenase-like hydrolase 521 737 1.5E-40 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 SUPERFAMILY SSF81665 290 326 4.97E-14 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 SUPERFAMILY SSF81665 423 518 4.97E-14 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 SUPERFAMILY SSF81665 772 812 4.97E-14 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 255 832 8.3E-194 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 524 538 1.6E-25 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 372 386 1.6E-25 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 723 742 1.6E-25 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 670 680 1.6E-25 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 648 659 1.6E-25 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 746 758 1.6E-25 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 294 803 1.8E-89 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 723 739 1.1E-11 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 695 711 1.1E-11 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 754 779 1.1E-11 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 Pfam PF00122 E1-E2 ATPase 294 515 3.7E-69 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 526 532 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 SUPERFAMILY SSF49503 20 122 2.24E-12 T 06-07-2017 IPR008972 Cupredoxin LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 237 833 8.3E-184 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 Gene3D G3DSA:2.60.40.420 31 122 3.4E-9 T 06-07-2017 IPR008972 Cupredoxin LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 SUPERFAMILY SSF81653 326 422 1.01E-28 T 06-07-2017 LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 SUPERFAMILY SSF56784 581 829 2.28E-55 T 06-07-2017 IPR023214 HAD-like domain LK06_RS22850 7c15202a8cb0d2c19631c8fe4031d782 937 SUPERFAMILY SSF56784 522 542 2.28E-55 T 06-07-2017 IPR023214 HAD-like domain LK06_RS09830 2a91c4f9af0c885140a5fb68e034074b 256 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 215 4.0E-56 T 06-07-2017 IPR018768 Domain of unknown function DUF2344 LK06_RS09830 2a91c4f9af0c885140a5fb68e034074b 256 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 191 8.3E-50 T 06-07-2017 IPR018768 Domain of unknown function DUF2344 LK06_RS27900 6ad092a1118fba00d727c1d169ccf7e8 101 Gene3D G3DSA:1.10.357.10 1 98 2.3E-14 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS27900 6ad092a1118fba00d727c1d169ccf7e8 101 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 1 99 2.3E-8 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 LK06_RS27900 6ad092a1118fba00d727c1d169ccf7e8 101 SUPERFAMILY SSF48498 1 98 2.56E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS18930 aa96b125e466a9dc8be80e4ff93685f3 227 SUPERFAMILY SSF54593 6 113 2.55E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS18930 aa96b125e466a9dc8be80e4ff93685f3 227 Gene3D G3DSA:3.10.180.10 124 226 1.5E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS18930 aa96b125e466a9dc8be80e4ff93685f3 227 Gene3D G3DSA:3.10.180.10 2 111 2.1E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS18930 aa96b125e466a9dc8be80e4ff93685f3 227 SUPERFAMILY SSF54593 125 226 9.13E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS07140 ff7a3d391bdc74a830ca53afcd9c14a0 213 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 6 212 30.645 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 LK06_RS07140 ff7a3d391bdc74a830ca53afcd9c14a0 213 PIRSF PIRSF000495 5 213 2.3E-64 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 LK06_RS07140 ff7a3d391bdc74a830ca53afcd9c14a0 213 SUPERFAMILY SSF52317 5 211 2.22E-50 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS07140 ff7a3d391bdc74a830ca53afcd9c14a0 213 Pfam PF00117 Glutamine amidotransferase class-I 9 203 3.5E-17 T 06-07-2017 IPR017926 Glutamine amidotransferase LK06_RS07140 ff7a3d391bdc74a830ca53afcd9c14a0 213 Gene3D G3DSA:3.40.50.880 4 211 7.0E-72 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS07140 ff7a3d391bdc74a830ca53afcd9c14a0 213 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 7 210 2.6E-60 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 LK06_RS20525 b30fcaab34b9c3527272eb23e86d1399 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 8.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS20525 b30fcaab34b9c3527272eb23e86d1399 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 8.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS20525 b30fcaab34b9c3527272eb23e86d1399 246 SUPERFAMILY SSF48498 92 234 1.07E-46 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS20525 b30fcaab34b9c3527272eb23e86d1399 246 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS20525 b30fcaab34b9c3527272eb23e86d1399 246 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 3.9E-19 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS20525 b30fcaab34b9c3527272eb23e86d1399 246 SUPERFAMILY SSF46689 17 88 8.72E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS20525 b30fcaab34b9c3527272eb23e86d1399 246 Gene3D G3DSA:1.10.357.10 17 208 4.0E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS02795 b3d1747bd9bb46cc6cf35f14c85ea825 146 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 31 82 4.3E-15 T 06-07-2017 IPR027805 Transposase, Helix-turn-helix domain LK06_RS06210 c923253f83e446be27b6d17881c3e071 226 Gene3D G3DSA:3.40.225.10 16 225 5.5E-71 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal LK06_RS06210 c923253f83e446be27b6d17881c3e071 226 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 22 193 5.7E-48 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal LK06_RS06210 c923253f83e446be27b6d17881c3e071 226 SMART SM01007 21 194 5.8E-61 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal LK06_RS06210 c923253f83e446be27b6d17881c3e071 226 SUPERFAMILY SSF53639 16 225 9.42E-63 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal LK06_RS06790 34a8fc769d7bb9a12fd201f38e768b37 153 Pfam PF01814 Hemerythrin HHE cation binding domain 13 132 1.5E-17 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 LK06_RS06790 34a8fc769d7bb9a12fd201f38e768b37 153 Gene3D G3DSA:1.20.120.520 12 135 4.7E-22 T 06-07-2017 LK06_RS05280 2a604af6d3f85c3b55ffed438fd10729 340 Pfam PF01636 Phosphotransferase enzyme family 33 252 7.5E-50 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS05280 2a604af6d3f85c3b55ffed438fd10729 340 Gene3D G3DSA:3.90.1200.10 127 314 6.4E-34 T 06-07-2017 LK06_RS05280 2a604af6d3f85c3b55ffed438fd10729 340 SUPERFAMILY SSF56112 7 313 6.4E-62 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS27620 385be25a4e40720724c8b4238b50e0fd 647 SUPERFAMILY SSF102114 262 432 7.85E-20 T 06-07-2017 LK06_RS27620 385be25a4e40720724c8b4238b50e0fd 647 Pfam PF02310 B12 binding domain 118 200 1.7E-11 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS27620 385be25a4e40720724c8b4238b50e0fd 647 Gene3D G3DSA:3.80.30.20 262 429 2.8E-18 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe LK06_RS27620 385be25a4e40720724c8b4238b50e0fd 647 SMART SM00729 262 478 5.6E-8 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS27620 385be25a4e40720724c8b4238b50e0fd 647 TIGRFAM TIGR03975 rSAM_ocin_1: ribosomal peptide maturation radical SAM protein 1 3 607 3.4E-178 T 06-07-2017 IPR023984 Ribosomal peptide maturation radical SAM protein 1 LK06_RS00615 6b9d85dac731d3e8ef8b7a7947113c52 392 Pfam PF01757 Acyltransferase family 33 355 7.8E-31 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 SMART SM00065 221 369 0.0034 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 SMART SM00065 52 200 2.2E-18 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 Gene3D G3DSA:3.30.450.40 202 370 3.9E-20 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 484 539 3.2E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 Gene3D G3DSA:3.30.565.10 464 570 1.4E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 SUPERFAMILY SSF55781 34 215 1.18E-38 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 Pfam PF13185 GAF domain 222 360 1.3E-12 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 Pfam PF13185 GAF domain 51 191 8.9E-18 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 Pfam PF07730 Histidine kinase 377 439 7.5E-11 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 Gene3D G3DSA:3.30.450.40 34 198 1.8E-33 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 SUPERFAMILY SSF55781 204 386 5.02E-23 T 06-07-2017 IPR029016 GAF domain-like LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 SUPERFAMILY SSF55874 480 569 1.19E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00125 4929cc67cae449bba8d332f1ed4bbd8f 576 SMART SM00387 481 571 3.8E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS27210 7494e8ada0ea6f8a0e084ceca33c12ed 464 Gene3D G3DSA:1.20.1250.20 19 193 3.7E-18 T 06-07-2017 LK06_RS27210 7494e8ada0ea6f8a0e084ceca33c12ed 464 Gene3D G3DSA:1.20.1250.20 206 394 2.0E-5 T 06-07-2017 LK06_RS27210 7494e8ada0ea6f8a0e084ceca33c12ed 464 SUPERFAMILY SSF103473 19 400 1.24E-32 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS27210 7494e8ada0ea6f8a0e084ceca33c12ed 464 Pfam PF07690 Major Facilitator Superfamily 20 366 4.2E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS02855 365e5063c764692324af377c4359d935 217 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 96 3.7E-12 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal LK06_RS02855 365e5063c764692324af377c4359d935 217 SUPERFAMILY SSF51735 1 205 3.76E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02855 365e5063c764692324af377c4359d935 217 Gene3D G3DSA:3.40.50.720 1 209 5.4E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 Pfam PF00106 short chain dehydrogenase 5 202 5.5E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 Gene3D G3DSA:3.40.50.720 3 238 5.2E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 3.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 3.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS13365 b81ed2e335b6b4564e6aa200b9813cf7 241 SUPERFAMILY SSF51735 4 238 1.01E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS07985 3410cea9ca3378fcaf41d5f22092681c 351 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 214 339 2.2E-13 T 06-07-2017 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain LK06_RS07985 3410cea9ca3378fcaf41d5f22092681c 351 SUPERFAMILY SSF69572 201 333 6.08E-7 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 LK06_RS07985 3410cea9ca3378fcaf41d5f22092681c 351 Gene3D G3DSA:3.40.50.720 202 330 6.7E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS07985 3410cea9ca3378fcaf41d5f22092681c 351 Gene3D G3DSA:1.10.10.10 57 98 4.1E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28545 9d8501489e54dcd7faa66b330f9f3310 335 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 10 256 4.8E-73 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain LK06_RS28545 9d8501489e54dcd7faa66b330f9f3310 335 Pfam PF01896 DNA primase small subunit 131 252 4.6E-9 T 06-07-2017 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69109|Reactome: R-HSA-69166|Reactome: R-HSA-69183 LK06_RS13235 6d98e348609e163d4694dd8beab67a63 262 Gene3D G3DSA:1.20.1080.10 31 198 1.6E-28 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 LK06_RS13235 6d98e348609e163d4694dd8beab67a63 262 PRINTS PR00783 Major intrinsic protein family signature 165 183 8.9E-11 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS13235 6d98e348609e163d4694dd8beab67a63 262 PRINTS PR00783 Major intrinsic protein family signature 80 104 8.9E-11 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS13235 6d98e348609e163d4694dd8beab67a63 262 PRINTS PR00783 Major intrinsic protein family signature 39 58 8.9E-11 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS13235 6d98e348609e163d4694dd8beab67a63 262 SUPERFAMILY SSF81338 35 257 1.96E-32 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 LK06_RS13235 6d98e348609e163d4694dd8beab67a63 262 Pfam PF00230 Major intrinsic protein 38 197 9.9E-18 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS13235 6d98e348609e163d4694dd8beab67a63 262 Gene3D G3DSA:1.20.1080.10 199 256 7.0E-4 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 LK06_RS13235 6d98e348609e163d4694dd8beab67a63 262 ProSitePatterns PS00221 MIP family signature. 98 106 - T 06-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 LK06_RS04595 450560f467362a7072f427a1e4290e37 361 Pfam PF00005 ABC transporter 35 189 6.5E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS04595 450560f467362a7072f427a1e4290e37 361 SMART SM00382 44 246 5.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS04595 450560f467362a7072f427a1e4290e37 361 Gene3D G3DSA:3.30.70.260 271 348 3.2E-20 T 06-07-2017 LK06_RS04595 450560f467362a7072f427a1e4290e37 361 Gene3D G3DSA:3.40.50.300 12 259 6.6E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04595 450560f467362a7072f427a1e4290e37 361 SUPERFAMILY SSF52540 13 257 6.03E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04595 450560f467362a7072f427a1e4290e37 361 SUPERFAMILY SSF55021 270 349 5.61E-17 T 06-07-2017 LK06_RS04595 450560f467362a7072f427a1e4290e37 361 SMART SM00930 271 346 6.3E-18 T 06-07-2017 IPR018449 NIL domain LK06_RS04595 450560f467362a7072f427a1e4290e37 361 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS04595 450560f467362a7072f427a1e4290e37 361 Pfam PF09383 NIL domain 273 345 7.0E-17 T 06-07-2017 IPR018449 NIL domain LK06_RS29485 621044e7df1c08647f80fd80520331c6 439 SUPERFAMILY SSF54909 79 432 2.68E-74 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS29485 621044e7df1c08647f80fd80520331c6 439 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 84 426 8.8E-82 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LK06_RS29485 621044e7df1c08647f80fd80520331c6 439 Pfam PF04261 Dyp-type peroxidase family 84 426 3.7E-89 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LK06_RS29485 621044e7df1c08647f80fd80520331c6 439 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 28 438 7.0E-131 T 06-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 LK06_RS21640 5f23a9980cbd13addeea5be37b96517c 451 SUPERFAMILY SSF48452 210 323 2.13E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS21640 5f23a9980cbd13addeea5be37b96517c 451 SUPERFAMILY SSF48452 379 409 2.13E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS21640 5f23a9980cbd13addeea5be37b96517c 451 Gene3D G3DSA:1.25.40.10 211 408 1.8E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS21640 5f23a9980cbd13addeea5be37b96517c 451 Gene3D G3DSA:1.10.260.40 9 70 6.1E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS00925 a85056167cede4d57c4fbd0bd2617f26 209 SMART SM00849 24 188 1.0E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS00925 a85056167cede4d57c4fbd0bd2617f26 209 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 5.1E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS00925 a85056167cede4d57c4fbd0bd2617f26 209 SUPERFAMILY SSF56281 18 201 3.66E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS00925 a85056167cede4d57c4fbd0bd2617f26 209 Gene3D G3DSA:3.60.15.10 24 192 3.3E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS03545 f5b5c2584bd0a6a689f0b5dfc4705871 144 Gene3D G3DSA:3.10.180.10 9 143 5.9E-7 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS03545 f5b5c2584bd0a6a689f0b5dfc4705871 144 SUPERFAMILY SSF54593 8 143 1.26E-8 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 Pfam PF00990 Diguanylate cyclase, GGDEF domain 588 754 3.8E-40 T 06-07-2017 IPR000160 GGDEF domain LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 SUPERFAMILY SSF55785 457 575 3.77E-17 T 06-07-2017 IPR000014 PAS domain LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 Gene3D G3DSA:3.30.70.270 589 767 1.9E-53 T 06-07-2017 LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 SMART SM00091 465 531 1.1E-9 T 06-07-2017 IPR000014 PAS domain LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 Gene3D G3DSA:3.20.20.450 772 1022 1.1E-73 T 06-07-2017 IPR001633 EAL domain LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 584 758 4.9E-37 T 06-07-2017 IPR000160 GGDEF domain LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 SUPERFAMILY SSF55073 593 761 4.08E-42 T 06-07-2017 IPR029787 Nucleotide cyclase LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 SUPERFAMILY SSF141868 776 1019 8.76E-56 T 06-07-2017 IPR001633 EAL domain LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 Pfam PF00563 EAL domain 776 1010 4.9E-51 T 06-07-2017 IPR001633 EAL domain LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 Gene3D G3DSA:3.30.450.20 458 577 1.3E-17 T 06-07-2017 LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 462 584 5.7E-13 T 06-07-2017 IPR000014 PAS domain LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 SMART SM00267 577 759 8.5E-52 T 06-07-2017 IPR000160 GGDEF domain LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 Pfam PF08448 PAS fold 474 579 1.6E-6 T 06-07-2017 IPR013656 PAS fold-4 LK06_RS23950 86f6210a86f8af56270e075f9506d050 1069 SMART SM00052 769 1015 6.7E-46 T 06-07-2017 IPR001633 EAL domain LK06_RS17710 ea2166dc89dfe4fb3c2d216ae98b185c 749 SUPERFAMILY SSF56112 82 331 9.36E-20 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS17710 ea2166dc89dfe4fb3c2d216ae98b185c 749 Pfam PF01636 Phosphotransferase enzyme family 81 289 2.2E-19 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS17710 ea2166dc89dfe4fb3c2d216ae98b185c 749 Pfam PF01636 Phosphotransferase enzyme family 421 661 2.4E-29 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS17710 ea2166dc89dfe4fb3c2d216ae98b185c 749 SUPERFAMILY SSF56112 422 676 7.27E-20 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS17710 ea2166dc89dfe4fb3c2d216ae98b185c 749 Gene3D G3DSA:3.90.1200.10 213 321 3.0E-12 T 06-07-2017 LK06_RS17710 ea2166dc89dfe4fb3c2d216ae98b185c 749 Gene3D G3DSA:3.90.1200.10 518 678 4.2E-14 T 06-07-2017 LK06_RS18990 2975dc2da9e3b76fffc5ff8ae14ea830 483 Gene3D G3DSA:3.40.309.10 269 454 4.0E-67 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS18990 2975dc2da9e3b76fffc5ff8ae14ea830 483 Pfam PF00171 Aldehyde dehydrogenase family 13 479 4.4E-157 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS18990 2975dc2da9e3b76fffc5ff8ae14ea830 483 SUPERFAMILY SSF53720 4 481 1.57E-151 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS18990 2975dc2da9e3b76fffc5ff8ae14ea830 483 Gene3D G3DSA:3.40.605.10 4 268 1.0E-78 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 SUPERFAMILY SSF49265 177 260 2.89E-17 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 ProSitePatterns PS01095 Chitinases family 18 active site. 384 392 - T 06-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 Gene3D G3DSA:3.20.20.80 271 592 5.1E-63 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 Gene3D G3DSA:2.60.40.10 176 257 1.1E-20 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 SMART SM00060 178 248 7.9E-12 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 Gene3D G3DSA:2.60.120.260 32 168 1.5E-11 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 SUPERFAMILY SSF49785 39 169 1.05E-13 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 SUPERFAMILY SSF51445 272 597 7.77E-55 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 Pfam PF02018 Carbohydrate binding domain 40 152 6.0E-14 T 06-07-2017 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 SMART SM00636 272 589 1.7E-7 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 Pfam PF00041 Fibronectin type III domain 180 251 9.5E-8 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 LK06_RS24655 d64b9923cb82886eedde94f6d7af0860 605 Pfam PF00704 Glycosyl hydrolases family 18 274 589 5.7E-24 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 LK06_RS02895 0249f62dd04cc3c4ff6d53e03ae91323 81 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 6.7E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS02895 0249f62dd04cc3c4ff6d53e03ae91323 81 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 6.7E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS02895 0249f62dd04cc3c4ff6d53e03ae91323 81 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 6.7E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS02895 0249f62dd04cc3c4ff6d53e03ae91323 81 Gene3D G3DSA:3.30.70.20 1 59 2.1E-13 T 06-07-2017 LK06_RS02895 0249f62dd04cc3c4ff6d53e03ae91323 81 SUPERFAMILY SSF54862 1 59 3.98E-12 T 06-07-2017 LK06_RS02895 0249f62dd04cc3c4ff6d53e03ae91323 81 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 59 1.1E-11 T 06-07-2017 LK06_RS06995 6d8970e77f2961716eee8cdd9848b8d3 246 SMART SM00882 7 201 2.9E-5 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 LK06_RS06995 6d8970e77f2961716eee8cdd9848b8d3 246 Pfam PF01144 Coenzyme A transferase 78 200 5.8E-8 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 LK06_RS06995 6d8970e77f2961716eee8cdd9848b8d3 246 Gene3D G3DSA:3.40.810.20 2 239 1.8E-62 T 06-07-2017 LK06_RS06995 6d8970e77f2961716eee8cdd9848b8d3 246 SUPERFAMILY SSF100950 1 238 6.28E-50 T 06-07-2017 LK06_RS32155 b532381542495f0aa3c1eedade8ecfdb 263 Gene3D G3DSA:3.40.50.1820 8 258 1.2E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS32155 b532381542495f0aa3c1eedade8ecfdb 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.8E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS32155 b532381542495f0aa3c1eedade8ecfdb 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 1.8E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS32155 b532381542495f0aa3c1eedade8ecfdb 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 1.8E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS32155 b532381542495f0aa3c1eedade8ecfdb 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 1.8E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS32155 b532381542495f0aa3c1eedade8ecfdb 263 Pfam PF12697 Alpha/beta hydrolase family 23 248 3.3E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS32155 b532381542495f0aa3c1eedade8ecfdb 263 SUPERFAMILY SSF53474 7 257 1.49E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS05080 2a901f2db9e75d789d7a0068fdfed50b 526 Gene3D G3DSA:3.90.76.10 49 203 7.7E-33 T 06-07-2017 LK06_RS05080 2a901f2db9e75d789d7a0068fdfed50b 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 444 3.3E-73 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS05080 2a901f2db9e75d789d7a0068fdfed50b 526 Gene3D G3DSA:3.10.105.10 282 494 5.2E-41 T 06-07-2017 LK06_RS05080 2a901f2db9e75d789d7a0068fdfed50b 526 SUPERFAMILY SSF53850 32 523 1.74E-94 T 06-07-2017 LK06_RS05080 2a901f2db9e75d789d7a0068fdfed50b 526 PIRSF PIRSF002741 12 511 1.1E-63 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LK06_RS30950 592a21e161b55f470639c9706f93c929 632 Gene3D G3DSA:3.40.50.980 346 408 1.3E-21 T 06-07-2017 LK06_RS30950 592a21e161b55f470639c9706f93c929 632 Gene3D G3DSA:3.40.50.980 191 290 1.3E-21 T 06-07-2017 LK06_RS30950 592a21e161b55f470639c9706f93c929 632 SUPERFAMILY SSF56801 349 611 1.44E-104 T 06-07-2017 LK06_RS30950 592a21e161b55f470639c9706f93c929 632 SUPERFAMILY SSF56801 18 295 1.44E-104 T 06-07-2017 LK06_RS30950 592a21e161b55f470639c9706f93c929 632 Gene3D G3DSA:2.30.38.10 409 469 3.8E-18 T 06-07-2017 LK06_RS30950 592a21e161b55f470639c9706f93c929 632 Pfam PF00501 AMP-binding enzyme 37 478 1.2E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS30950 592a21e161b55f470639c9706f93c929 632 Gene3D G3DSA:3.40.50.980 43 190 6.1E-26 T 06-07-2017 LK06_RS30950 592a21e161b55f470639c9706f93c929 632 Gene3D G3DSA:3.30.300.30 476 598 2.6E-6 T 06-07-2017 LK06_RS20245 615fa75885ad3eb175ca713c221af712 176 Pfam PF07681 DoxX 28 130 2.7E-20 T 06-07-2017 IPR032808 DoxX family LK06_RS12950 710c7731f3cb0cec4f83d18eafe97f61 184 Gene3D G3DSA:3.40.50.700 25 149 4.6E-33 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12950 710c7731f3cb0cec4f83d18eafe97f61 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 2.0E-24 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12950 710c7731f3cb0cec4f83d18eafe97f61 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 41.923 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12950 710c7731f3cb0cec4f83d18eafe97f61 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12950 710c7731f3cb0cec4f83d18eafe97f61 184 SUPERFAMILY SSF56770 9 154 9.29E-65 T 06-07-2017 LK06_RS12950 710c7731f3cb0cec4f83d18eafe97f61 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 2.0E-68 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.4E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.4E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.4E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.4E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 SUPERFAMILY SSF54686 1 135 9.68E-56 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.3E-54 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 4.8E-48 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.083 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12280 ab7b4a56d07cb23a869f5c111857c818 139 Gene3D G3DSA:3.90.1170.10 23 136 3.6E-53 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 LK06_RS19590 adbcc9bab9006532c428fcf8b98d4106 208 SUPERFAMILY SSF46955 2 70 2.01E-17 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS19590 adbcc9bab9006532c428fcf8b98d4106 208 SMART SM00422 1 67 1.8E-12 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS19590 adbcc9bab9006532c428fcf8b98d4106 208 Pfam PF13411 MerR HTH family regulatory protein 1 65 3.9E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS19590 adbcc9bab9006532c428fcf8b98d4106 208 Gene3D G3DSA:1.10.1660.10 2 72 1.6E-19 T 06-07-2017 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 Pfam PF00009 Elongation factor Tu GTP binding domain 534 694 3.2E-32 T 06-07-2017 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 441 1035 3.8E-229 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 Gene3D G3DSA:2.40.30.10 705 799 1.3E-22 T 06-07-2017 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 SUPERFAMILY SSF52156 814 943 1.96E-35 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 PRINTS PR00315 GTP-binding elongation factor signature 601 612 1.2E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 PRINTS PR00315 GTP-binding elongation factor signature 637 646 1.2E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 PRINTS PR00315 GTP-binding elongation factor signature 533 546 1.2E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 PRINTS PR00315 GTP-binding elongation factor signature 585 595 1.2E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 Gene3D G3DSA:3.40.50.300 525 693 1.1E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 1035 16.73 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 532 691 6.4E-30 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 Pfam PF11987 Translation-initiation factor 2 825 926 4.0E-33 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 SUPERFAMILY SSF50447 938 1035 1.3E-25 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 ProSitePatterns PS01176 Initiation factor 2 signature. 988 1010 - T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 Gene3D G3DSA:3.40.50.10050 835 915 4.3E-22 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 SUPERFAMILY SSF52540 530 696 8.27E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 Gene3D G3DSA:2.40.30.10 938 1035 4.2E-31 T 06-07-2017 LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 450 495 1.2E-7 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 51 2.0E-12 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal LK06_RS24765 d18336136247c5c6eca5f3e6b3e7fa6b 1036 SUPERFAMILY SSF50447 707 790 2.75E-24 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS28340 476a056c35bb20407ba24ecb7bdd833c 387 Pfam PF13692 Glycosyl transferases group 1 189 328 1.6E-13 T 06-07-2017 LK06_RS28340 476a056c35bb20407ba24ecb7bdd833c 387 Gene3D G3DSA:3.40.50.2000 184 341 1.9E-5 T 06-07-2017 LK06_RS28340 476a056c35bb20407ba24ecb7bdd833c 387 SUPERFAMILY SSF53756 3 362 1.06E-33 T 06-07-2017 LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 Gene3D G3DSA:2.160.20.10 21 357 7.3E-32 T 06-07-2017 IPR012334 Pectin lyase fold LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 SMART SM00710 289 316 2400.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 SMART SM00710 323 355 4600.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 SMART SM00710 225 246 1000.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 SMART SM00710 203 224 34.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 SMART SM00710 253 288 750.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 SMART SM00710 170 192 17.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 SMART SM00710 124 146 1900.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 SUPERFAMILY SSF51126 19 356 1.2E-40 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 Pfam PF13229 Right handed beta helix region 109 249 3.5E-14 T 06-07-2017 LK06_RS07880 6f76f058b75877ced7872ec953fd2314 367 Pfam PF13229 Right handed beta helix region 256 365 1.3E-7 T 06-07-2017 LK06_RS29950 42fa3683bb4d0d4be2fcbfd7983eb8c2 265 Gene3D G3DSA:3.40.50.620 3 264 2.2E-83 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS29950 42fa3683bb4d0d4be2fcbfd7983eb8c2 265 PIRSF PIRSF000090 3 265 3.9E-82 T 06-07-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 LK06_RS29950 42fa3683bb4d0d4be2fcbfd7983eb8c2 265 SMART SM00893 24 218 2.3E-55 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 LK06_RS29950 42fa3683bb4d0d4be2fcbfd7983eb8c2 265 SUPERFAMILY SSF52402 3 260 2.72E-69 T 06-07-2017 LK06_RS29950 42fa3683bb4d0d4be2fcbfd7983eb8c2 265 Pfam PF01012 Electron transfer flavoprotein domain 25 213 1.0E-43 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 LK06_RS27460 12ca005b073a925d5738d17f7eaa2cd3 505 Pfam PF04183 IucA / IucC family 145 333 3.5E-29 T 06-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 LK06_RS27460 12ca005b073a925d5738d17f7eaa2cd3 505 Pfam PF06276 Ferric iron reductase FhuF-like transporter 342 436 6.0E-13 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 SUPERFAMILY SSF103491 2 427 2.35E-126 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 Pfam PF00344 SecY translocase 73 420 3.4E-117 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 Gene3D G3DSA:1.10.3370.10 2 437 3.3E-158 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 432 5.4E-149 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 316 338 4.5E-108 T 06-07-2017 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 371 389 4.5E-108 T 06-07-2017 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 274 293 4.5E-108 T 06-07-2017 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 4.5E-108 T 06-07-2017 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 4.5E-108 T 06-07-2017 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 4.5E-108 T 06-07-2017 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 4.5E-108 T 06-07-2017 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 4.5E-108 T 06-07-2017 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 405 423 4.5E-108 T 06-07-2017 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 PIRSF PIRSF004557 1 437 2.1E-124 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LK06_RS12210 e7d9dce3b2a5214a4d5f79efcc622486 437 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 436 29.601 T 06-07-2017 IPR026593 Protein translocase subunit SecY LK06_RS19805 7daa9c0a10457f392dc86233f2a62155 335 Pfam PF00487 Fatty acid desaturase 62 276 2.3E-21 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 LK06_RS19805 7daa9c0a10457f392dc86233f2a62155 335 PRINTS PR00075 Fatty acid desaturase family 1 signature 221 242 3.8E-17 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 LK06_RS19805 7daa9c0a10457f392dc86233f2a62155 335 PRINTS PR00075 Fatty acid desaturase family 1 signature 264 278 3.8E-17 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 LK06_RS19805 7daa9c0a10457f392dc86233f2a62155 335 PRINTS PR00075 Fatty acid desaturase family 1 signature 84 104 3.8E-17 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 LK06_RS19805 7daa9c0a10457f392dc86233f2a62155 335 PRINTS PR00075 Fatty acid desaturase family 1 signature 61 83 3.8E-17 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 LK06_RS30650 12f58c741f338dd3d187cfb2efbd59ff 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 4.0E-31 T 06-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 LK06_RS29055 0d90e3daf8ed7232acba8bc70f799d49 81 Gene3D G3DSA:3.40.50.720 19 80 6.6E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS09005 27c3e4de0228ca627fe01db7e7ffade9 366 Pfam PF06032 Protein of unknown function (DUF917) 8 360 2.9E-124 T 06-07-2017 IPR010318 Protein of unknown function DUF917 LK06_RS09005 27c3e4de0228ca627fe01db7e7ffade9 366 SUPERFAMILY SSF160991 4 361 2.62E-118 T 06-07-2017 LK06_RS09005 27c3e4de0228ca627fe01db7e7ffade9 366 Gene3D G3DSA:3.40.1610.10 3 222 1.2E-85 T 06-07-2017 IPR027479 Protein of unknown function DUF917, N-terminal LK06_RS09005 27c3e4de0228ca627fe01db7e7ffade9 366 Gene3D G3DSA:2.40.390.10 241 353 1.7E-24 T 06-07-2017 IPR024071 Protein of unknown function DUF917, C-terminal LK06_RS12045 0b4f9da3607f083bc953f409b71cf456 376 Gene3D G3DSA:2.60.40.230 43 115 2.1E-4 T 06-07-2017 IPR027273 Neocarzinostatin-like LK06_RS12045 0b4f9da3607f083bc953f409b71cf456 376 SUPERFAMILY SSF49319 42 135 1.19E-5 T 06-07-2017 IPR027273 Neocarzinostatin-like LK06_RS10705 b3aff08323673c79bee82d4bfb7f78c3 385 Gene3D G3DSA:1.20.140.10 224 383 6.6E-59 T 06-07-2017 LK06_RS10705 b3aff08323673c79bee82d4bfb7f78c3 385 SUPERFAMILY SSF56645 4 246 1.3E-78 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS10705 b3aff08323673c79bee82d4bfb7f78c3 385 Gene3D G3DSA:2.40.110.10 122 223 1.8E-37 T 06-07-2017 LK06_RS10705 b3aff08323673c79bee82d4bfb7f78c3 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS10705 b3aff08323673c79bee82d4bfb7f78c3 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 223 7.1E-26 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS10705 b3aff08323673c79bee82d4bfb7f78c3 385 Gene3D G3DSA:1.10.540.10 6 120 1.0E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS10705 b3aff08323673c79bee82d4bfb7f78c3 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 383 3.9E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS10705 b3aff08323673c79bee82d4bfb7f78c3 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 3.4E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS10705 b3aff08323673c79bee82d4bfb7f78c3 385 SUPERFAMILY SSF47203 233 383 1.93E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS11455 c56ada820635e883f33def712e649194 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 186 8.9E-25 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS11455 c56ada820635e883f33def712e649194 194 Pfam PF04542 Sigma-70 region 2 36 104 8.7E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS11455 c56ada820635e883f33def712e649194 194 Gene3D G3DSA:1.10.10.10 130 189 7.3E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11455 c56ada820635e883f33def712e649194 194 Gene3D G3DSA:1.10.1740.10 29 126 1.4E-21 T 06-07-2017 LK06_RS11455 c56ada820635e883f33def712e649194 194 SUPERFAMILY SSF88659 118 189 3.92E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS11455 c56ada820635e883f33def712e649194 194 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 59 91 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS11455 c56ada820635e883f33def712e649194 194 SUPERFAMILY SSF88946 27 119 2.24E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS11455 c56ada820635e883f33def712e649194 194 Pfam PF04545 Sigma-70, region 4 136 184 8.8E-14 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS12825 cb1fc21872f7bd14b5b6caf750346df8 96 Gene3D G3DSA:1.10.1200.10 22 94 8.0E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS12825 cb1fc21872f7bd14b5b6caf750346df8 96 Pfam PF00550 Phosphopantetheine attachment site 22 91 1.0E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS12825 cb1fc21872f7bd14b5b6caf750346df8 96 SUPERFAMILY SSF47336 22 93 1.06E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS21590 42ada0451f50948e9b00c4b0c713863f 392 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 71 124 5.0E-9 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS21590 42ada0451f50948e9b00c4b0c713863f 392 SUPERFAMILY SSF56349 69 373 4.94E-53 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS21590 42ada0451f50948e9b00c4b0c713863f 392 Gene3D G3DSA:1.10.443.10 178 372 1.6E-29 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS21590 42ada0451f50948e9b00c4b0c713863f 392 Gene3D G3DSA:1.10.150.130 70 163 2.4E-14 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS21590 42ada0451f50948e9b00c4b0c713863f 392 Pfam PF00589 Phage integrase family 175 366 2.8E-17 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 SUPERFAMILY SSF52172 10 139 2.7E-16 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 SUPERFAMILY SSF46894 141 216 7.14E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 Gene3D G3DSA:1.10.10.10 125 216 2.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 SMART SM00421 154 211 6.5E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 Gene3D G3DSA:3.40.50.2300 9 124 8.6E-15 T 06-07-2017 LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 210 1.2E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 1.8E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 1.8E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 1.8E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS26205 ef94735579c742dc9105af81c87640fa 218 Pfam PF00072 Response regulator receiver domain 11 122 7.4E-10 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS19595 d4c9d9096ae33f56787aee9e7daca3e6 533 Pfam PF00743 Flavin-binding monooxygenase-like 8 343 4.2E-18 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 LK06_RS19595 d4c9d9096ae33f56787aee9e7daca3e6 533 Gene3D G3DSA:3.50.50.60 317 488 5.5E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19595 d4c9d9096ae33f56787aee9e7daca3e6 533 Gene3D G3DSA:3.50.50.60 3 219 2.4E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19595 d4c9d9096ae33f56787aee9e7daca3e6 533 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 138 4.4E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS19595 d4c9d9096ae33f56787aee9e7daca3e6 533 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 4.4E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS19595 d4c9d9096ae33f56787aee9e7daca3e6 533 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 169 193 4.4E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS19595 d4c9d9096ae33f56787aee9e7daca3e6 533 SUPERFAMILY SSF51905 5 235 5.38E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19595 d4c9d9096ae33f56787aee9e7daca3e6 533 SUPERFAMILY SSF51905 278 484 2.01E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS00415 27bd7bba3f819cb60f0570e9982d174f 326 SUPERFAMILY SSF52922 189 322 2.88E-40 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS00415 27bd7bba3f819cb60f0570e9982d174f 326 Gene3D G3DSA:3.40.50.970 3 181 1.7E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS00415 27bd7bba3f819cb60f0570e9982d174f 326 SUPERFAMILY SSF52518 3 181 3.48E-63 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS00415 27bd7bba3f819cb60f0570e9982d174f 326 SMART SM00861 3 178 1.6E-60 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS00415 27bd7bba3f819cb60f0570e9982d174f 326 Pfam PF02780 Transketolase, C-terminal domain 194 314 2.4E-38 T 06-07-2017 IPR033248 Transketolase, C-terminal domain LK06_RS00415 27bd7bba3f819cb60f0570e9982d174f 326 Gene3D G3DSA:3.40.50.920 196 320 7.7E-43 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS00415 27bd7bba3f819cb60f0570e9982d174f 326 Pfam PF02779 Transketolase, pyrimidine binding domain 3 177 2.2E-42 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 SUPERFAMILY SSF69318 439 692 2.09E-31 T 06-07-2017 LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 815 845 0.0018 T 06-07-2017 IPR006530 YD repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1 29 4.3E-4 T 06-07-2017 IPR006530 YD repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 241 281 2.8E-9 T 06-07-2017 IPR006530 YD repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 199 239 2.2E-5 T 06-07-2017 IPR006530 YD repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 871 899 3.1E-4 T 06-07-2017 IPR006530 YD repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 106 145 1.3E-10 T 06-07-2017 IPR006530 YD repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 178 218 3.3E-6 T 06-07-2017 IPR006530 YD repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 328 355 0.0024 T 06-07-2017 IPR006530 YD repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 64 104 1.3E-9 T 06-07-2017 IPR006530 YD repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 159 195 0.003 T 06-07-2017 IPR006530 YD repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 981 1065 5.3E-14 T 06-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Gene3D G3DSA:2.130.10.130 442 625 1.2E-16 T 06-07-2017 LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 43 78 5.6E-10 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 106 141 7.7E-11 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 220 257 3.5E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 85 120 2.0E-9 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 241 277 2.2E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 346 376 7.0E-5 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 262 297 1.6E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 64 100 3.4E-8 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 1 28 6.3E-5 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 178 215 1.4E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF05593 RHS Repeat 148 192 1.0E-6 T 06-07-2017 IPR031325 RHS repeat LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 546 605 3.9E-11 T 06-07-2017 LK06_RS18050 1531ceb82c45e6073e4f9bd35338289f 1330 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 449 507 1.7E-13 T 06-07-2017 LK06_RS10385 3c0190adcae41baa5476f8f9d741f652 345 SUPERFAMILY SSF56059 25 219 5.02E-23 T 06-07-2017 LK06_RS10385 3c0190adcae41baa5476f8f9d741f652 345 Gene3D G3DSA:3.30.470.20 21 218 2.9E-13 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS29025 53fdf9edf3a34722ceda5887a809dbaa 337 Gene3D G3DSA:3.40.50.2300 172 305 1.4E-17 T 06-07-2017 LK06_RS29025 53fdf9edf3a34722ceda5887a809dbaa 337 Gene3D G3DSA:3.40.50.2300 48 171 4.7E-30 T 06-07-2017 LK06_RS29025 53fdf9edf3a34722ceda5887a809dbaa 337 Pfam PF13407 Periplasmic binding protein domain 61 301 8.1E-40 T 06-07-2017 IPR025997 Periplasmic binding protein LK06_RS29025 53fdf9edf3a34722ceda5887a809dbaa 337 SUPERFAMILY SSF53822 53 326 1.3E-52 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS01730 b96a1d0292c4a48ad769f83a65004b82 358 SMART SM00354 10 80 4.7E-21 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS01730 b96a1d0292c4a48ad769f83a65004b82 358 Gene3D G3DSA:3.40.50.2300 60 190 3.1E-21 T 06-07-2017 LK06_RS01730 b96a1d0292c4a48ad769f83a65004b82 358 Pfam PF13377 Periplasmic binding protein-like domain 184 342 1.0E-27 T 06-07-2017 LK06_RS01730 b96a1d0292c4a48ad769f83a65004b82 358 SUPERFAMILY SSF53822 85 327 1.12E-45 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS01730 b96a1d0292c4a48ad769f83a65004b82 358 Gene3D G3DSA:3.40.50.2300 191 324 4.2E-30 T 06-07-2017 LK06_RS01730 b96a1d0292c4a48ad769f83a65004b82 358 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 06-07-2017 LK06_RS01730 b96a1d0292c4a48ad769f83a65004b82 358 SUPERFAMILY SSF47413 9 65 1.56E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS01730 b96a1d0292c4a48ad769f83a65004b82 358 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 2.2E-16 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS01730 b96a1d0292c4a48ad769f83a65004b82 358 Gene3D G3DSA:1.10.260.40 9 59 2.3E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS30530 fddb9f7414568d6504858d57f52890aa 157 SUPERFAMILY SSF55874 56 140 3.41E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS30530 fddb9f7414568d6504858d57f52890aa 157 Pfam PF13581 Histidine kinase-like ATPase domain 36 145 1.1E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04865 ea8b8d0e682348244b12fdf4e47ced60 457 Gene3D G3DSA:3.40.605.10 6 243 5.4E-90 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS04865 ea8b8d0e682348244b12fdf4e47ced60 457 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 231 238 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 LK06_RS04865 ea8b8d0e682348244b12fdf4e47ced60 457 Gene3D G3DSA:3.40.309.10 244 428 1.2E-53 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS04865 ea8b8d0e682348244b12fdf4e47ced60 457 Pfam PF00171 Aldehyde dehydrogenase family 5 448 2.5E-153 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS04865 ea8b8d0e682348244b12fdf4e47ced60 457 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 LK06_RS04865 ea8b8d0e682348244b12fdf4e47ced60 457 SUPERFAMILY SSF53720 5 450 6.68E-150 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 SUPERFAMILY SSF48179 158 292 1.42E-41 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 160 270 6.7E-26 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 228 240 - T 06-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 SUPERFAMILY SSF51735 1 143 2.02E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 224 251 3.6E-37 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 3.6E-37 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 149 177 3.6E-37 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 3.6E-37 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 3.6E-37 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 291 2.5E-103 T 06-07-2017 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 Gene3D G3DSA:1.10.1040.10 162 270 6.4E-36 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 Gene3D G3DSA:3.40.50.720 1 161 8.1E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 SMART SM01350 160 292 3.0E-6 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 LK06_RS28380 99f698fc4ef219bf6f768dd298e2b181 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 143 2.2E-36 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 LK06_RS11320 8a1c55dd4b4eb7f969d155e8fb7630dc 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 268 5.4E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS11320 8a1c55dd4b4eb7f969d155e8fb7630dc 283 Gene3D G3DSA:1.10.3720.10 46 267 9.2E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS11320 8a1c55dd4b4eb7f969d155e8fb7630dc 283 SUPERFAMILY SSF161098 80 266 2.62E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS00035 44573e1e40beeddf49abee9d1a88ddd6 317 Pfam PF00561 alpha/beta hydrolase fold 47 158 5.6E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS00035 44573e1e40beeddf49abee9d1a88ddd6 317 Gene3D G3DSA:3.40.50.1820 21 292 3.7E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS00035 44573e1e40beeddf49abee9d1a88ddd6 317 SUPERFAMILY SSF53474 16 290 9.51E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS18790 c798253048b4ff31fe3d90c576bb4185 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 6.5E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18790 c798253048b4ff31fe3d90c576bb4185 377 SUPERFAMILY SSF56645 2 237 8.12E-65 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS18790 c798253048b4ff31fe3d90c576bb4185 377 Gene3D G3DSA:1.10.540.10 1 117 4.0E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18790 c798253048b4ff31fe3d90c576bb4185 377 Gene3D G3DSA:2.40.110.10 119 215 7.1E-34 T 06-07-2017 LK06_RS18790 c798253048b4ff31fe3d90c576bb4185 377 Gene3D G3DSA:1.20.140.10 216 375 2.1E-24 T 06-07-2017 LK06_RS18790 c798253048b4ff31fe3d90c576bb4185 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 371 4.8E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS18790 c798253048b4ff31fe3d90c576bb4185 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 213 2.0E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS18790 c798253048b4ff31fe3d90c576bb4185 377 SUPERFAMILY SSF47203 226 373 1.54E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS23760 98a147d77b69f6d95d0db2c6d7f807a9 263 Pfam PF14581 SseB protein C-terminal domain 151 260 3.4E-25 T 06-07-2017 IPR027945 SseB protein, C-terminal LK06_RS23760 98a147d77b69f6d95d0db2c6d7f807a9 263 Pfam PF07179 SseB protein N-terminal domain 29 137 9.8E-14 T 06-07-2017 IPR009839 SseB protein N-terminal domain LK06_RS22725 a4e7c28a76c69afcae1b48f81a793eb7 415 SUPERFAMILY SSF51905 2 164 7.51E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS22725 a4e7c28a76c69afcae1b48f81a793eb7 415 SUPERFAMILY SSF51905 288 363 7.51E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS22725 a4e7c28a76c69afcae1b48f81a793eb7 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 3.4E-5 T 06-07-2017 LK06_RS22725 a4e7c28a76c69afcae1b48f81a793eb7 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 3.4E-5 T 06-07-2017 LK06_RS22725 a4e7c28a76c69afcae1b48f81a793eb7 415 Gene3D G3DSA:3.40.50.720 112 154 1.1E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22725 a4e7c28a76c69afcae1b48f81a793eb7 415 Gene3D G3DSA:3.40.50.720 2 56 1.1E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06110 25424d38a0c3f507acacedf187ec452e 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 5.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS06110 25424d38a0c3f507acacedf187ec452e 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 5.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS06110 25424d38a0c3f507acacedf187ec452e 222 Gene3D G3DSA:1.10.357.10 2 205 1.2E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS06110 25424d38a0c3f507acacedf187ec452e 222 SUPERFAMILY SSF48498 81 203 3.34E-11 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS06110 25424d38a0c3f507acacedf187ec452e 222 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 80 197 1.6E-5 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 LK06_RS06110 25424d38a0c3f507acacedf187ec452e 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 1.4E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS06110 25424d38a0c3f507acacedf187ec452e 222 SUPERFAMILY SSF46689 1 68 8.48E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS22830 d69b3fc9295376cc5e063a56808741b6 107 SUPERFAMILY SSF50037 35 105 1.58E-17 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal LK06_RS22830 d69b3fc9295376cc5e063a56808741b6 107 SMART SM00899 31 105 1.3E-18 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 LK06_RS22830 d69b3fc9295376cc5e063a56808741b6 107 Pfam PF04023 FeoA domain 32 105 1.8E-17 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 LK06_RS11015 b09c26b87f32cbcb31cf54334b34ad4f 374 SUPERFAMILY SSF51905 2 213 1.42E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS11015 b09c26b87f32cbcb31cf54334b34ad4f 374 SUPERFAMILY SSF51905 334 372 1.42E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS11015 b09c26b87f32cbcb31cf54334b34ad4f 374 Pfam PF01266 FAD dependent oxidoreductase 3 370 1.2E-43 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS11015 b09c26b87f32cbcb31cf54334b34ad4f 374 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 2 366 2.3E-96 T 06-07-2017 IPR017741 FAD-dependent oxidoreductase, HpnW LK06_RS11015 b09c26b87f32cbcb31cf54334b34ad4f 374 Gene3D G3DSA:3.50.50.60 277 288 4.2E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS11015 b09c26b87f32cbcb31cf54334b34ad4f 374 Gene3D G3DSA:3.50.50.60 2 70 4.2E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS11015 b09c26b87f32cbcb31cf54334b34ad4f 374 Gene3D G3DSA:3.50.50.60 344 371 4.2E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS11015 b09c26b87f32cbcb31cf54334b34ad4f 374 Gene3D G3DSA:3.50.50.60 130 212 4.2E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS32100 457fda42d9fa5e9ea91b1469c5dbe9fc 344 SUPERFAMILY SSF51569 15 292 4.58E-53 T 06-07-2017 LK06_RS32100 457fda42d9fa5e9ea91b1469c5dbe9fc 344 Gene3D G3DSA:3.20.20.70 14 273 1.1E-46 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS32100 457fda42d9fa5e9ea91b1469c5dbe9fc 344 Gene3D G3DSA:1.10.8.60 287 343 6.0E-7 T 06-07-2017 LK06_RS32100 457fda42d9fa5e9ea91b1469c5dbe9fc 344 Pfam PF00682 HMGL-like 17 273 1.1E-40 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 LK06_RS18220 bfbff7ce9dcb453cc35d270ad9078e3e 290 Gene3D G3DSA:1.10.10.10 118 171 1.1E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18220 bfbff7ce9dcb453cc35d270ad9078e3e 290 Gene3D G3DSA:3.10.450.50 182 283 5.2E-8 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS18220 bfbff7ce9dcb453cc35d270ad9078e3e 290 Gene3D G3DSA:1.10.1740.10 14 109 6.2E-16 T 06-07-2017 LK06_RS18220 bfbff7ce9dcb453cc35d270ad9078e3e 290 SUPERFAMILY SSF88659 100 171 5.23E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS18220 bfbff7ce9dcb453cc35d270ad9078e3e 290 SUPERFAMILY SSF54427 182 285 3.66E-12 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS18220 bfbff7ce9dcb453cc35d270ad9078e3e 290 SUPERFAMILY SSF88946 13 104 1.84E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS18220 bfbff7ce9dcb453cc35d270ad9078e3e 290 Pfam PF04542 Sigma-70 region 2 22 86 4.6E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS18220 bfbff7ce9dcb453cc35d270ad9078e3e 290 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 170 5.7E-19 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS18220 bfbff7ce9dcb453cc35d270ad9078e3e 290 Pfam PF08281 Sigma-70, region 4 118 168 1.1E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14730 f5ce0a7cc699288db9a97db793e6c4aa 325 Pfam PF00196 Bacterial regulatory proteins, luxR family 266 315 2.1E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14730 f5ce0a7cc699288db9a97db793e6c4aa 325 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 265 279 2.2E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14730 f5ce0a7cc699288db9a97db793e6c4aa 325 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 279 295 2.2E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14730 f5ce0a7cc699288db9a97db793e6c4aa 325 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 295 307 2.2E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14730 f5ce0a7cc699288db9a97db793e6c4aa 325 SUPERFAMILY SSF46894 254 324 5.1E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS14730 f5ce0a7cc699288db9a97db793e6c4aa 325 Gene3D G3DSA:1.10.10.10 258 324 2.4E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14730 f5ce0a7cc699288db9a97db793e6c4aa 325 SMART SM00421 262 319 3.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS23090 381086ed9f661145845651bb354a6950 884 Pfam PF03781 Sulfatase-modifying factor enzyme 1 637 871 3.6E-32 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 LK06_RS23090 381086ed9f661145845651bb354a6950 884 Gene3D G3DSA:3.40.50.300 318 338 2.2E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23090 381086ed9f661145845651bb354a6950 884 Gene3D G3DSA:3.90.1580.10 654 880 2.0E-42 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 LK06_RS23090 381086ed9f661145845651bb354a6950 884 SUPERFAMILY SSF56436 635 874 6.83E-43 T 06-07-2017 IPR016187 C-type lectin fold LK06_RS23090 381086ed9f661145845651bb354a6950 884 SUPERFAMILY SSF52540 314 408 2.8E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25950 88888d24cc9ac73ae72b59244bc4479f 1385 Gene3D G3DSA:3.40.1140.10 31 120 4.7E-22 T 06-07-2017 LK06_RS25950 88888d24cc9ac73ae72b59244bc4479f 1385 Gene3D G3DSA:3.40.1140.10 1279 1350 4.7E-22 T 06-07-2017 LK06_RS25950 88888d24cc9ac73ae72b59244bc4479f 1385 TIGRFAM TIGR02680 TIGR02680: TIGR02680 family protein 31 1381 0.0 T 06-07-2017 IPR013496 Conserved hypothetical protein CHP02680 LK06_RS25950 88888d24cc9ac73ae72b59244bc4479f 1385 SUPERFAMILY SSF52540 45 210 4.02E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25950 88888d24cc9ac73ae72b59244bc4479f 1385 SUPERFAMILY SSF52540 1249 1336 4.02E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25950 88888d24cc9ac73ae72b59244bc4479f 1385 SUPERFAMILY SSF52540 311 342 4.02E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25950 88888d24cc9ac73ae72b59244bc4479f 1385 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1247 1333 5.3E-18 T 06-07-2017 LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 Gene3D G3DSA:3.40.50.720 6 228 1.3E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 SUPERFAMILY SSF51735 4 220 1.51E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 216 4.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 Pfam PF00106 short chain dehydrogenase 7 189 5.2E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28200 5b5a3731278c5d752f47db4da93c14b4 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS07750 a1972067359c04640ce417b5623557d0 366 Pfam PF02277 Phosphoribosyltransferase 13 346 7.5E-103 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS07750 a1972067359c04640ce417b5623557d0 366 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 17 346 8.1E-104 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS07750 a1972067359c04640ce417b5623557d0 366 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 15 354 32.372 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS07750 a1972067359c04640ce417b5623557d0 366 Gene3D G3DSA:3.40.50.10210 73 335 7.2E-89 T 06-07-2017 LK06_RS07750 a1972067359c04640ce417b5623557d0 366 SUPERFAMILY SSF52733 7 350 1.26E-89 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS07750 a1972067359c04640ce417b5623557d0 366 Gene3D G3DSA:1.10.1610.10 6 72 1.9E-18 T 06-07-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS12840 0e3b3a773d829919e25a39ef168e1979 347 SUPERFAMILY SSF103025 13 253 2.51E-25 T 06-07-2017 LK06_RS12840 0e3b3a773d829919e25a39ef168e1979 347 Gene3D G3DSA:3.30.1360.120 119 212 2.4E-6 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 LK06_RS12840 0e3b3a773d829919e25a39ef168e1979 347 PIRSF PIRSF006487 3 346 1.7E-18 T 06-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 LK06_RS12840 0e3b3a773d829919e25a39ef168e1979 347 Pfam PF01571 Aminomethyltransferase folate-binding domain 33 220 7.1E-16 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal LK06_RS11775 6dbd67e7a79fc7e8a250eed1f22fc59b 380 Gene3D G3DSA:1.20.120.420 19 172 1.6E-35 T 06-07-2017 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 LK06_RS11775 6dbd67e7a79fc7e8a250eed1f22fc59b 380 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 19 360 1.8E-102 T 06-07-2017 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 LK06_RS11775 6dbd67e7a79fc7e8a250eed1f22fc59b 380 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 16 371 34.683 T 06-07-2017 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 LK06_RS11775 6dbd67e7a79fc7e8a250eed1f22fc59b 380 SUPERFAMILY SSF100950 19 364 3.71E-94 T 06-07-2017 LK06_RS11775 6dbd67e7a79fc7e8a250eed1f22fc59b 380 Gene3D G3DSA:3.40.50.10470 173 368 1.8E-59 T 06-07-2017 LK06_RS11775 6dbd67e7a79fc7e8a250eed1f22fc59b 380 Pfam PF01008 Initiation factor 2 subunit family 86 361 2.1E-59 T 06-07-2017 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 LK06_RS11775 6dbd67e7a79fc7e8a250eed1f22fc59b 380 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 50 361 3.4E-79 T 06-07-2017 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 LK06_RS20535 67bb72439e403729c7672641f73d432f 259 Pfam PF13183 4Fe-4S dicluster domain 169 241 6.0E-12 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LK06_RS20535 67bb72439e403729c7672641f73d432f 259 Gene3D G3DSA:1.10.1060.10 129 257 2.5E-39 T 06-07-2017 LK06_RS20535 67bb72439e403729c7672641f73d432f 259 SUPERFAMILY SSF54292 24 128 6.97E-29 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS20535 67bb72439e403729c7672641f73d432f 259 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 171 182 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS20535 67bb72439e403729c7672641f73d432f 259 Gene3D G3DSA:3.10.20.30 23 128 8.0E-39 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS20535 67bb72439e403729c7672641f73d432f 259 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 28 133 7.1E-36 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20535 67bb72439e403729c7672641f73d432f 259 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 31 251 2.4E-80 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 LK06_RS20535 67bb72439e403729c7672641f73d432f 259 SUPERFAMILY SSF46548 129 256 4.88E-34 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 LK06_RS31705 65122c4bc900b63f09beedb07a25a8d1 101 Pfam PF00550 Phosphopantetheine attachment site 25 93 1.8E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31705 65122c4bc900b63f09beedb07a25a8d1 101 Gene3D G3DSA:1.10.1200.10 20 96 3.9E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31705 65122c4bc900b63f09beedb07a25a8d1 101 SUPERFAMILY SSF47336 19 97 1.1E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 SUPERFAMILY SSF52540 509 780 2.38E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 Gene3D G3DSA:1.20.1580.10 565 687 1.4E-35 T 06-07-2017 LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 SUPERFAMILY SSF52540 313 468 6.86E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 SUPERFAMILY SSF52540 23 71 6.86E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 Gene3D G3DSA:1.20.1580.10 301 376 5.0E-30 T 06-07-2017 LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 Gene3D G3DSA:1.20.1580.10 111 187 5.0E-30 T 06-07-2017 LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 Gene3D G3DSA:3.40.50.300 377 492 3.5E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 Gene3D G3DSA:3.40.50.300 17 79 3.5E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 Gene3D G3DSA:3.40.50.300 504 561 5.0E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 Gene3D G3DSA:3.40.50.300 688 805 5.0E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 Gene3D G3DSA:1.10.8.280 190 300 3.7E-7 T 06-07-2017 LK06_RS17730 e8593b26535f3caff4cd523752ee66ad 809 Pfam PF00005 ABC transporter 517 727 2.0E-9 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 SUPERFAMILY SSF56112 15 280 6.07E-73 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 SMART SM00220 18 281 2.6E-52 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 Pfam PF00069 Protein kinase domain 18 231 2.2E-48 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 Gene3D G3DSA:3.30.200.20 10 83 1.1E-24 T 06-07-2017 LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 Pfam PF03793 PASTA domain 514 576 2.4E-16 T 06-07-2017 IPR005543 PASTA domain LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 Pfam PF03793 PASTA domain 446 509 1.1E-11 T 06-07-2017 IPR005543 PASTA domain LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 Pfam PF03793 PASTA domain 379 440 7.3E-11 T 06-07-2017 IPR005543 PASTA domain LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 Pfam PF03793 PASTA domain 581 640 6.4E-10 T 06-07-2017 IPR005543 PASTA domain LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 SUPERFAMILY SSF54184 581 640 8.37E-7 T 06-07-2017 LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 Gene3D G3DSA:1.10.510.10 84 269 2.3E-48 T 06-07-2017 LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 SMART SM00740 374 441 3.6E-14 T 06-07-2017 IPR005543 PASTA domain LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 SMART SM00740 442 509 8.5E-12 T 06-07-2017 IPR005543 PASTA domain LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 SMART SM00740 577 641 6.2E-16 T 06-07-2017 IPR005543 PASTA domain LK06_RS07445 a19136a56d389edb354b82c40b438efa 641 SMART SM00740 510 576 1.6E-17 T 06-07-2017 IPR005543 PASTA domain LK06_RS27540 7e591460f06aef3ec8d65707f1818edf 445 Gene3D G3DSA:2.30.40.10 6 71 1.8E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS27540 7e591460f06aef3ec8d65707f1818edf 445 Pfam PF01979 Amidohydrolase family 54 425 1.5E-25 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS27540 7e591460f06aef3ec8d65707f1818edf 445 SUPERFAMILY SSF51556 58 373 2.5E-99 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS27540 7e591460f06aef3ec8d65707f1818edf 445 Gene3D G3DSA:3.20.20.140 72 393 5.1E-129 T 06-07-2017 LK06_RS27540 7e591460f06aef3ec8d65707f1818edf 445 TIGRFAM TIGR03178 allantoinase: allantoinase 5 442 5.2E-189 T 06-07-2017 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 LK06_RS27540 7e591460f06aef3ec8d65707f1818edf 445 SUPERFAMILY SSF51338 5 57 7.57E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS27540 7e591460f06aef3ec8d65707f1818edf 445 SUPERFAMILY SSF51338 373 436 7.57E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS14680 a1980feda77b9fa72cc817b2a2c04eb2 389 Gene3D G3DSA:3.90.1150.10 254 387 2.0E-27 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS14680 a1980feda77b9fa72cc817b2a2c04eb2 389 SUPERFAMILY SSF53383 5 387 2.26E-108 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS14680 a1980feda77b9fa72cc817b2a2c04eb2 389 Pfam PF00155 Aminotransferase class I and II 32 381 2.1E-65 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS14680 a1980feda77b9fa72cc817b2a2c04eb2 389 Gene3D G3DSA:3.40.640.10 44 253 2.3E-74 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS01865 60742cabcdcfe7a30f4519a9a74d1675 1202 SUPERFAMILY SSF53335 60 330 5.78E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS01865 60742cabcdcfe7a30f4519a9a74d1675 1202 SUPERFAMILY SSF53335 361 488 5.78E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS01865 60742cabcdcfe7a30f4519a9a74d1675 1202 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 373 379 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LK06_RS01865 60742cabcdcfe7a30f4519a9a74d1675 1202 Gene3D G3DSA:3.40.50.150 211 328 3.0E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS01865 60742cabcdcfe7a30f4519a9a74d1675 1202 Gene3D G3DSA:3.40.50.150 360 492 3.0E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS16475 79cd0263218f0b9199b164f171dff61a 138 SUPERFAMILY SSF54637 2 121 2.74E-20 T 06-07-2017 IPR029069 HotDog domain LK06_RS16475 79cd0263218f0b9199b164f171dff61a 138 Pfam PF01575 MaoC like domain 10 110 3.5E-6 T 06-07-2017 IPR002539 MaoC-like domain LK06_RS16475 79cd0263218f0b9199b164f171dff61a 138 Gene3D G3DSA:3.10.129.10 2 128 1.3E-17 T 06-07-2017 IPR029069 HotDog domain LK06_RS05330 be50fb9217ec5400e7e8dd2fffb7ac04 207 SUPERFAMILY SSF48498 93 205 4.75E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS05330 be50fb9217ec5400e7e8dd2fffb7ac04 207 SUPERFAMILY SSF46689 18 98 4.72E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS05330 be50fb9217ec5400e7e8dd2fffb7ac04 207 Gene3D G3DSA:1.10.10.60 55 71 1.4E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS05330 be50fb9217ec5400e7e8dd2fffb7ac04 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05330 be50fb9217ec5400e7e8dd2fffb7ac04 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05330 be50fb9217ec5400e7e8dd2fffb7ac04 207 Gene3D G3DSA:1.10.10.60 24 54 9.8E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS05330 be50fb9217ec5400e7e8dd2fffb7ac04 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 2.1E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05330 be50fb9217ec5400e7e8dd2fffb7ac04 207 Gene3D G3DSA:1.10.357.10 72 205 3.6E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS23665 a3806f954571ec8012f347939b2187c2 410 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 112 261 3.7E-7 T 06-07-2017 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 SUPERFAMILY SSF52540 27 243 7.67E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 SUPERFAMILY SSF46894 825 894 7.48E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 Pfam PF00196 Bacterial regulatory proteins, luxR family 833 888 7.0E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 SMART SM00421 831 888 2.4E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 Pfam PF13191 AAA ATPase domain 37 178 5.9E-8 T 06-07-2017 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 Gene3D G3DSA:1.25.40.10 473 799 2.2E-22 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 SUPERFAMILY SSF48452 475 584 8.22E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 SUPERFAMILY SSF48452 604 729 8.86E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 848 864 9.6E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 834 848 9.6E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 864 876 9.6E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 Gene3D G3DSA:1.10.10.10 828 894 2.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30245 bd70bad9ef1e5cf6aced413fd2660767 894 Gene3D G3DSA:3.40.50.300 44 187 8.7E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31900 cc24ba8c7d80f39f43ab2570e41c45cd 280 Gene3D G3DSA:3.20.20.70 11 259 2.5E-73 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS31900 cc24ba8c7d80f39f43ab2570e41c45cd 280 SUPERFAMILY SSF51569 11 257 2.97E-66 T 06-07-2017 LK06_RS31900 cc24ba8c7d80f39f43ab2570e41c45cd 280 Pfam PF01791 DeoC/LacD family aldolase 45 240 5.6E-43 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 LK06_RS31900 cc24ba8c7d80f39f43ab2570e41c45cd 280 SMART SM01133 24 241 4.4E-41 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 LK06_RS31900 cc24ba8c7d80f39f43ab2570e41c45cd 280 PIRSF PIRSF038992 5 270 5.2E-83 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 LK06_RS12700 e491e046345bd035d22df74c81eae3db 655 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 35 648 8.4E-195 T 06-07-2017 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 LK06_RS12700 e491e046345bd035d22df74c81eae3db 655 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 284 499 1.7E-51 T 06-07-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 LK06_RS12700 e491e046345bd035d22df74c81eae3db 655 Gene3D G3DSA:3.40.50.970 256 449 3.6E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS12700 e491e046345bd035d22df74c81eae3db 655 SUPERFAMILY SSF53323 37 259 1.18E-16 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 LK06_RS12700 e491e046345bd035d22df74c81eae3db 655 Gene3D G3DSA:3.40.920.10 35 234 2.0E-22 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 LK06_RS12700 e491e046345bd035d22df74c81eae3db 655 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 43 231 4.3E-24 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 LK06_RS12700 e491e046345bd035d22df74c81eae3db 655 SUPERFAMILY SSF52922 550 654 1.73E-15 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS12700 e491e046345bd035d22df74c81eae3db 655 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 554 625 1.4E-8 T 06-07-2017 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II LK06_RS12700 e491e046345bd035d22df74c81eae3db 655 Gene3D G3DSA:3.40.50.920 550 652 1.6E-12 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS12700 e491e046345bd035d22df74c81eae3db 655 SUPERFAMILY SSF52518 258 525 1.03E-59 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS31895 c112e48e126d113c2692c89b8226cac0 372 Pfam PF01959 3-dehydroquinate synthase (EC 4.6.1.3) 7 372 3.3E-100 T 06-07-2017 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 LK06_RS31895 c112e48e126d113c2692c89b8226cac0 372 ProDom PD017907 3-DEHYDROQUINATE UPF0245 SYNTHASE LYASE PREDICTED SYNTHASE-LIKE ALTERNATIVE T19N8 MM1272 MK1408 153 371 3.0E-85 T 06-07-2017 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 LK06_RS11785 828d1419e27dfde280082c2c9851fa13 258 Pfam PF13559 Domain of unknown function (DUF4129) 162 232 1.2E-14 T 06-07-2017 IPR025403 Domain of unknown function DUF4129 LK06_RS31690 1c7b3d5e2db77773659ef624022c30b2 453 SUPERFAMILY SSF52777 14 216 1.78E-21 T 06-07-2017 LK06_RS31690 1c7b3d5e2db77773659ef624022c30b2 453 Pfam PF00668 Condensation domain 17 297 1.3E-15 T 06-07-2017 IPR001242 Condensation domain LK06_RS31690 1c7b3d5e2db77773659ef624022c30b2 453 SUPERFAMILY SSF52777 204 436 3.34E-16 T 06-07-2017 LK06_RS28040 d0fbcf8889aa2d1058244679629180c9 277 Gene3D G3DSA:3.30.1360.130 214 267 4.1E-7 T 06-07-2017 LK06_RS28040 d0fbcf8889aa2d1058244679629180c9 277 Gene3D G3DSA:3.40.50.10780 1 213 1.8E-76 T 06-07-2017 IPR027476 D-aminopeptidase, N-terminal LK06_RS28040 d0fbcf8889aa2d1058244679629180c9 277 SUPERFAMILY SSF63992 1 267 5.75E-86 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase LK06_RS28040 d0fbcf8889aa2d1058244679629180c9 277 Pfam PF04951 D-aminopeptidase 1 262 5.3E-92 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase LK06_RS28040 d0fbcf8889aa2d1058244679629180c9 277 PIRSF PIRSF015853 1 274 1.7E-97 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase LK06_RS00120 bd19f033ebb1ff3e43e7780dc92500e0 233 PIRSF PIRSF036990 6 225 4.7E-66 T 06-07-2017 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON LK06_RS00120 bd19f033ebb1ff3e43e7780dc92500e0 233 SUPERFAMILY SSF54631 7 146 6.19E-34 T 06-07-2017 LK06_RS00120 bd19f033ebb1ff3e43e7780dc92500e0 233 SMART SM00116 15 63 3.2E-7 T 06-07-2017 IPR000644 CBS domain LK06_RS00120 bd19f033ebb1ff3e43e7780dc92500e0 233 SMART SM00116 96 144 5.1E-10 T 06-07-2017 IPR000644 CBS domain LK06_RS00120 bd19f033ebb1ff3e43e7780dc92500e0 233 Gene3D G3DSA:3.10.580.10 8 144 2.1E-30 T 06-07-2017 LK06_RS00120 bd19f033ebb1ff3e43e7780dc92500e0 233 Pfam PF00571 CBS domain 90 141 4.3E-15 T 06-07-2017 IPR000644 CBS domain LK06_RS00120 bd19f033ebb1ff3e43e7780dc92500e0 233 Pfam PF00571 CBS domain 8 59 7.4E-12 T 06-07-2017 IPR000644 CBS domain LK06_RS00120 bd19f033ebb1ff3e43e7780dc92500e0 233 Pfam PF04972 BON domain 146 212 2.3E-12 T 06-07-2017 IPR007055 BON domain LK06_RS23710 99b7abf5be1917ccd4e760dcd8198f9f 262 SUPERFAMILY SSF88713 67 261 5.93E-36 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS23710 99b7abf5be1917ccd4e760dcd8198f9f 262 Pfam PF01522 Polysaccharide deacetylase 72 192 2.8E-15 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS23710 99b7abf5be1917ccd4e760dcd8198f9f 262 Gene3D G3DSA:3.20.20.370 65 261 2.0E-36 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS11225 1f8559e4b974df717c5aaf802ac309ea 140 SMART SM00232 1 134 3.8E-27 T 06-07-2017 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 LK06_RS11225 1f8559e4b974df717c5aaf802ac309ea 140 Gene3D G3DSA:3.40.140.10 1 136 2.5E-36 T 06-07-2017 LK06_RS11225 1f8559e4b974df717c5aaf802ac309ea 140 Pfam PF14464 Prokaryotic homologs of the JAB domain 6 113 1.3E-27 T 06-07-2017 IPR028090 JAB domain, prokaryotic LK06_RS11225 1f8559e4b974df717c5aaf802ac309ea 140 SUPERFAMILY SSF102712 1 132 1.7E-27 T 06-07-2017 LK06_RS09130 d4426cd5e6c17959c6cc7b334b56c605 233 Gene3D G3DSA:1.10.443.10 17 69 3.1E-37 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS09130 d4426cd5e6c17959c6cc7b334b56c605 233 Gene3D G3DSA:1.10.443.10 103 233 3.1E-37 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS09130 d4426cd5e6c17959c6cc7b334b56c605 233 Pfam PF00589 Phage integrase family 26 233 1.5E-19 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS09130 d4426cd5e6c17959c6cc7b334b56c605 233 SUPERFAMILY SSF56349 2 70 2.09E-37 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS09130 d4426cd5e6c17959c6cc7b334b56c605 233 SUPERFAMILY SSF56349 103 233 2.09E-37 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS30190 f1fb3ed6004b457f7a3a1ba237cc1789 314 PRINTS PR01438 Universal stress protein signature 111 123 4.6E-12 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS30190 f1fb3ed6004b457f7a3a1ba237cc1789 314 PRINTS PR01438 Universal stress protein signature 129 151 4.6E-12 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS30190 f1fb3ed6004b457f7a3a1ba237cc1789 314 PRINTS PR01438 Universal stress protein signature 2 20 4.6E-12 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS30190 f1fb3ed6004b457f7a3a1ba237cc1789 314 SUPERFAMILY SSF52402 3 153 2.09E-27 T 06-07-2017 LK06_RS30190 f1fb3ed6004b457f7a3a1ba237cc1789 314 Gene3D G3DSA:3.40.50.620 170 312 1.4E-25 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS30190 f1fb3ed6004b457f7a3a1ba237cc1789 314 Gene3D G3DSA:3.40.50.620 1 152 1.9E-29 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS30190 f1fb3ed6004b457f7a3a1ba237cc1789 314 Pfam PF00582 Universal stress protein family 174 312 5.1E-22 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS30190 f1fb3ed6004b457f7a3a1ba237cc1789 314 Pfam PF00582 Universal stress protein family 1 151 4.8E-25 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS30190 f1fb3ed6004b457f7a3a1ba237cc1789 314 SUPERFAMILY SSF52402 174 313 6.53E-23 T 06-07-2017 LK06_RS15595 41a4bb1a9ecadd2862c7595c43bdcb4e 250 Gene3D G3DSA:2.40.260.10 89 236 3.3E-25 T 06-07-2017 IPR023365 Sortase domain LK06_RS15595 41a4bb1a9ecadd2862c7595c43bdcb4e 250 Pfam PF04203 Sortase family 97 234 1.2E-23 T 06-07-2017 IPR005754 Sortase family LK06_RS15595 41a4bb1a9ecadd2862c7595c43bdcb4e 250 SUPERFAMILY SSF63817 86 237 4.05E-30 T 06-07-2017 IPR023365 Sortase domain LK06_RS15595 41a4bb1a9ecadd2862c7595c43bdcb4e 250 TIGRFAM TIGR01076 sortase_fam: sortase 95 239 2.2E-16 T 06-07-2017 IPR005754 Sortase family LK06_RS13360 e5b3282f98551bdc75c5dfdb83fcd127 286 Pfam PF03466 LysR substrate binding domain 97 279 1.4E-13 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS13360 e5b3282f98551bdc75c5dfdb83fcd127 286 SUPERFAMILY SSF46785 3 83 1.27E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13360 e5b3282f98551bdc75c5dfdb83fcd127 286 SUPERFAMILY SSF53850 96 282 1.02E-16 T 06-07-2017 LK06_RS13360 e5b3282f98551bdc75c5dfdb83fcd127 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13360 e5b3282f98551bdc75c5dfdb83fcd127 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13360 e5b3282f98551bdc75c5dfdb83fcd127 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS13360 e5b3282f98551bdc75c5dfdb83fcd127 286 Gene3D G3DSA:3.40.190.10 101 188 3.5E-10 T 06-07-2017 LK06_RS13360 e5b3282f98551bdc75c5dfdb83fcd127 286 Gene3D G3DSA:1.10.10.10 2 81 2.3E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13360 e5b3282f98551bdc75c5dfdb83fcd127 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.2E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 SMART SM00419 167 215 3.3E-14 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 78 95 - T 06-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 1.1E-17 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 Gene3D G3DSA:1.10.10.10 146 222 1.1E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 SUPERFAMILY SSF51206 3 142 2.36E-38 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 SUPERFAMILY SSF46785 145 222 4.08E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 PRINTS PR00103 cAMP-dependent protein kinase signature 31 45 1.9E-6 T 06-07-2017 LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 PRINTS PR00103 cAMP-dependent protein kinase signature 46 60 1.9E-6 T 06-07-2017 LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 PRINTS PR00103 cAMP-dependent protein kinase signature 76 85 1.9E-6 T 06-07-2017 LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 PRINTS PR00103 cAMP-dependent protein kinase signature 88 99 1.9E-6 T 06-07-2017 LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 110 1.3E-25 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 SMART SM00100 10 128 1.5E-25 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain LK06_RS14130 e304a9247aa40473c2c9516ccc963401 224 Gene3D G3DSA:2.60.120.10 2 145 9.4E-40 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS05140 0dce8409c5890bc2ba5880b3eeb8a3a1 196 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 190 1.2E-78 T 06-07-2017 IPR021441 Protein of unknown function DUF3090 LK06_RS05140 0dce8409c5890bc2ba5880b3eeb8a3a1 196 Pfam PF11290 Protein of unknown function (DUF3090) 7 186 4.2E-68 T 06-07-2017 IPR021441 Protein of unknown function DUF3090 LK06_RS13565 e277a859357721d7de4440487baeeb85 224 SUPERFAMILY SSF48498 113 223 4.0E-32 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS13565 e277a859357721d7de4440487baeeb85 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 6.6E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS13565 e277a859357721d7de4440487baeeb85 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 60 6.6E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS13565 e277a859357721d7de4440487baeeb85 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 47 93 4.5E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS13565 e277a859357721d7de4440487baeeb85 224 SUPERFAMILY SSF46689 33 112 1.28E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS13565 e277a859357721d7de4440487baeeb85 224 Gene3D G3DSA:1.10.357.10 106 224 5.5E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS13565 e277a859357721d7de4440487baeeb85 224 Gene3D G3DSA:1.10.10.60 34 93 8.0E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS10725 21e06601995905ffcdd423e162ca695c 314 Pfam PF00682 HMGL-like 18 290 7.4E-49 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 LK06_RS10725 21e06601995905ffcdd423e162ca695c 314 SUPERFAMILY SSF51569 15 310 3.48E-73 T 06-07-2017 LK06_RS10725 21e06601995905ffcdd423e162ca695c 314 Gene3D G3DSA:3.20.20.70 17 304 1.9E-85 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS14745 64fc685095cf257dac067fe5716548cd 152 Gene3D G3DSA:1.10.1660.10 21 115 7.6E-22 T 06-07-2017 LK06_RS14745 64fc685095cf257dac067fe5716548cd 152 SUPERFAMILY SSF46955 20 107 2.93E-19 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS14745 64fc685095cf257dac067fe5716548cd 152 SMART SM00422 20 89 8.3E-26 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS14745 64fc685095cf257dac067fe5716548cd 152 Pfam PF13411 MerR HTH family regulatory protein 20 87 1.1E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS14745 64fc685095cf257dac067fe5716548cd 152 ProSitePatterns PS00552 MerR-type HTH domain signature. 23 45 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 Pfam PF01025 GrpE 46 187 1.3E-34 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 PRINTS PR00773 GrpE protein signature 166 185 1.9E-25 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 PRINTS PR00773 GrpE protein signature 64 80 1.9E-25 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 PRINTS PR00773 GrpE protein signature 139 154 1.9E-25 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 PRINTS PR00773 GrpE protein signature 92 107 1.9E-25 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 Gene3D G3DSA:2.30.22.10 131 188 3.8E-22 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 SUPERFAMILY SSF51064 133 188 4.45E-16 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 Hamap MF_01151 Protein GrpE [grpE]. 3 187 17.336 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 Gene3D G3DSA:3.90.20.20 45 130 5.9E-20 T 06-07-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 ProSitePatterns PS01071 grpE protein signature. 142 185 - T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LK06_RS14755 c33b0768ee735c1519379476d8c3f31f 221 SUPERFAMILY SSF58014 46 131 3.14E-17 T 06-07-2017 LK06_RS09840 e13801195b418cdee22f3615251e967e 402 SUPERFAMILY SSF53474 295 398 2.68E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS09840 e13801195b418cdee22f3615251e967e 402 SUPERFAMILY SSF53474 11 264 2.68E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS09840 e13801195b418cdee22f3615251e967e 402 Gene3D G3DSA:3.40.50.1820 127 398 5.3E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS09840 e13801195b418cdee22f3615251e967e 402 Gene3D G3DSA:1.20.1440.110 8 123 4.8E-28 T 06-07-2017 LK06_RS17130 a53c5ead8e134297b3364e64716d98a0 545 Pfam PF00589 Phage integrase family 299 480 1.1E-11 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS17130 a53c5ead8e134297b3364e64716d98a0 545 Gene3D G3DSA:1.10.443.10 297 489 3.1E-34 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS17130 a53c5ead8e134297b3364e64716d98a0 545 SUPERFAMILY SSF56349 229 490 1.24E-47 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS17130 a53c5ead8e134297b3364e64716d98a0 545 SUPERFAMILY SSF56349 122 179 1.24E-47 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS17130 a53c5ead8e134297b3364e64716d98a0 545 Gene3D G3DSA:1.10.150.130 234 265 3.1E-14 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS17130 a53c5ead8e134297b3364e64716d98a0 545 Gene3D G3DSA:1.10.150.130 123 183 3.1E-14 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS19965 d823eea6369b74790a2d80c590560803 89 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 86 9.9E-12 T 06-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family LK06_RS19965 d823eea6369b74790a2d80c590560803 89 SUPERFAMILY SSF143011 3 84 3.01E-21 T 06-07-2017 LK06_RS30615 5d49f8f8a9ed3336bfca653ee2b10674 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 1.4E-18 T 06-07-2017 LK06_RS30615 5d49f8f8a9ed3336bfca653ee2b10674 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 1.4E-18 T 06-07-2017 LK06_RS30615 5d49f8f8a9ed3336bfca653ee2b10674 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 20 42 1.4E-18 T 06-07-2017 LK06_RS30615 5d49f8f8a9ed3336bfca653ee2b10674 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 357 1.4E-18 T 06-07-2017 LK06_RS30615 5d49f8f8a9ed3336bfca653ee2b10674 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 1.4E-18 T 06-07-2017 LK06_RS30615 5d49f8f8a9ed3336bfca653ee2b10674 412 SUPERFAMILY SSF51905 18 184 1.99E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30615 5d49f8f8a9ed3336bfca653ee2b10674 412 SUPERFAMILY SSF51905 278 382 1.99E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30615 5d49f8f8a9ed3336bfca653ee2b10674 412 Pfam PF01494 FAD binding domain 20 355 2.2E-21 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS30615 5d49f8f8a9ed3336bfca653ee2b10674 412 Gene3D G3DSA:3.50.50.60 279 363 3.1E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30615 5d49f8f8a9ed3336bfca653ee2b10674 412 Gene3D G3DSA:3.50.50.60 19 189 3.1E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30720 506cef76f74bc069c51af883f0b9ed5d 116 Pfam PF03795 YCII-related domain 20 103 4.9E-10 T 06-07-2017 IPR005545 YCII-related LK06_RS30720 506cef76f74bc069c51af883f0b9ed5d 116 Gene3D G3DSA:3.30.70.1060 1 114 1.6E-29 T 06-07-2017 LK06_RS30720 506cef76f74bc069c51af883f0b9ed5d 116 SUPERFAMILY SSF54909 1 112 4.56E-23 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS08805 2c1dccd3ceee5b02898ce156b80f6571 538 Pfam PF07690 Major Facilitator Superfamily 40 431 4.9E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS08805 2c1dccd3ceee5b02898ce156b80f6571 538 Gene3D G3DSA:1.20.1250.20 292 442 1.6E-15 T 06-07-2017 LK06_RS08805 2c1dccd3ceee5b02898ce156b80f6571 538 Gene3D G3DSA:1.20.1250.20 35 214 1.8E-25 T 06-07-2017 LK06_RS08805 2c1dccd3ceee5b02898ce156b80f6571 538 Gene3D G3DSA:1.20.1250.20 501 525 1.6E-15 T 06-07-2017 LK06_RS08805 2c1dccd3ceee5b02898ce156b80f6571 538 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 35 444 1.5E-78 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS08805 2c1dccd3ceee5b02898ce156b80f6571 538 SUPERFAMILY SSF103473 20 218 2.62E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08805 2c1dccd3ceee5b02898ce156b80f6571 538 SUPERFAMILY SSF103473 500 525 2.62E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08805 2c1dccd3ceee5b02898ce156b80f6571 538 SUPERFAMILY SSF103473 270 441 2.62E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS09285 d7e5fff275ca7d2929609ecc7c77c9ab 404 Pfam PF01548 Transposase 11 166 3.0E-45 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS09285 d7e5fff275ca7d2929609ecc7c77c9ab 404 Pfam PF02371 Transposase IS116/IS110/IS902 family 274 357 7.7E-24 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 LK06_RS16485 d7e5fff275ca7d2929609ecc7c77c9ab 404 Pfam PF01548 Transposase 11 166 3.0E-45 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS16485 d7e5fff275ca7d2929609ecc7c77c9ab 404 Pfam PF02371 Transposase IS116/IS110/IS902 family 274 357 7.7E-24 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 LK06_RS14310 d7e5fff275ca7d2929609ecc7c77c9ab 404 Pfam PF01548 Transposase 11 166 3.0E-45 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS14310 d7e5fff275ca7d2929609ecc7c77c9ab 404 Pfam PF02371 Transposase IS116/IS110/IS902 family 274 357 7.7E-24 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 LK06_RS05755 71aabaa9dbc0483d7b9c1fdf854bed7e 572 SUPERFAMILY SSF52540 335 520 8.89E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05755 71aabaa9dbc0483d7b9c1fdf854bed7e 572 SUPERFAMILY SSF52540 4 46 8.89E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05755 71aabaa9dbc0483d7b9c1fdf854bed7e 572 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 566 4.8E-158 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 LK06_RS05755 71aabaa9dbc0483d7b9c1fdf854bed7e 572 PIRSF PIRSF003128 1 571 1.4E-153 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 LK06_RS05755 71aabaa9dbc0483d7b9c1fdf854bed7e 572 Gene3D G3DSA:3.40.50.300 443 531 3.8E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05755 71aabaa9dbc0483d7b9c1fdf854bed7e 572 Gene3D G3DSA:3.40.50.300 2 205 2.6E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05755 71aabaa9dbc0483d7b9c1fdf854bed7e 572 Pfam PF02463 RecF/RecN/SMC N terminal domain 12 525 6.9E-18 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal LK06_RS05755 71aabaa9dbc0483d7b9c1fdf854bed7e 572 SUPERFAMILY SSF52540 2 216 3.1E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07690 e498dc45be7e4985abe6978ae6999a17 236 SUPERFAMILY SSF50370 114 234 1.49E-31 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS07690 e498dc45be7e4985abe6978ae6999a17 236 SMART SM00458 107 235 1.7E-18 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS07690 e498dc45be7e4985abe6978ae6999a17 236 Gene3D G3DSA:2.80.10.50 109 235 2.5E-32 T 06-07-2017 LK06_RS07690 e498dc45be7e4985abe6978ae6999a17 236 Pfam PF00652 Ricin-type beta-trefoil lectin domain 110 232 1.3E-22 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS00080 32cfd090580f9b071442231470be365f 132 Gene3D G3DSA:3.30.2130.10 2 128 2.1E-50 T 06-07-2017 LK06_RS00080 32cfd090580f9b071442231470be365f 132 SUPERFAMILY SSF55021 70 127 5.04E-19 T 06-07-2017 LK06_RS00080 32cfd090580f9b071442231470be365f 132 SUPERFAMILY SSF55021 2 65 4.81E-14 T 06-07-2017 LK06_RS00080 32cfd090580f9b071442231470be365f 132 Pfam PF10000 ACT domain 2 68 1.0E-23 T 06-07-2017 IPR018717 Domain of unknown function DUF2241 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 Gene3D G3DSA:3.50.50.60 11 210 6.9E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.0E-9 T 06-07-2017 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 318 3.0E-9 T 06-07-2017 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 202 220 3.0E-9 T 06-07-2017 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 SUPERFAMILY SSF51905 11 51 1.88E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 SUPERFAMILY SSF51905 90 397 1.88E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 327 8.5E-14 T 06-07-2017 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 Gene3D G3DSA:3.50.50.60 211 399 8.4E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 202 227 4.5E-8 T 06-07-2017 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 303 317 4.5E-8 T 06-07-2017 LK06_RS13220 c8061253547510f1b2ffa840c4f734c0 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 4.5E-8 T 06-07-2017 LK06_RS23370 cce4b23fd7792bc1e917d4de670a23d6 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 96 1.6E-15 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 LK06_RS23370 cce4b23fd7792bc1e917d4de670a23d6 107 SUPERFAMILY SSF52091 2 96 6.08E-21 T 06-07-2017 IPR002645 STAS domain LK06_RS23370 cce4b23fd7792bc1e917d4de670a23d6 107 Pfam PF13466 STAS domain 10 89 2.9E-15 T 06-07-2017 IPR002645 STAS domain LK06_RS23370 cce4b23fd7792bc1e917d4de670a23d6 107 Gene3D G3DSA:3.30.750.24 2 96 2.4E-26 T 06-07-2017 IPR002645 STAS domain LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 Gene3D G3DSA:1.10.580.10 22 248 8.2E-67 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 SUPERFAMILY SSF48256 13 385 2.49E-104 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 ProSitePatterns PS00480 Citrate synthase signature. 270 282 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 PRINTS PR00143 Citrate synthase signature 188 203 1.0E-33 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 PRINTS PR00143 Citrate synthase signature 210 238 1.0E-33 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 PRINTS PR00143 Citrate synthase signature 342 356 1.0E-33 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 PRINTS PR00143 Citrate synthase signature 139 152 1.0E-33 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 PRINTS PR00143 Citrate synthase signature 322 338 1.0E-33 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 PRINTS PR00143 Citrate synthase signature 263 283 1.0E-33 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 Pfam PF00285 Citrate synthase, C-terminal domain 16 371 1.8E-103 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 PIRSF PIRSF001369 8 387 1.8E-100 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type LK06_RS25355 27762368eb4f3df06fc7fc49ae1d3530 388 Gene3D G3DSA:1.10.230.10 249 334 1.6E-22 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 LK06_RS26115 00395771d7f77709da0f89fbaab8e8c1 276 SUPERFAMILY SSF46785 17 92 8.97E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26115 00395771d7f77709da0f89fbaab8e8c1 276 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 84 3.6E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS26115 00395771d7f77709da0f89fbaab8e8c1 276 Gene3D G3DSA:1.10.10.10 19 80 6.8E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26115 00395771d7f77709da0f89fbaab8e8c1 276 SMART SM00345 27 84 5.4E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS26115 00395771d7f77709da0f89fbaab8e8c1 276 SMART SM00866 104 244 2.1E-42 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS26115 00395771d7f77709da0f89fbaab8e8c1 276 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 9.7E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS26115 00395771d7f77709da0f89fbaab8e8c1 276 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 9.7E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS26115 00395771d7f77709da0f89fbaab8e8c1 276 Pfam PF07702 UTRA domain 104 244 6.2E-40 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS26115 00395771d7f77709da0f89fbaab8e8c1 276 SUPERFAMILY SSF64288 72 251 7.07E-52 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS26115 00395771d7f77709da0f89fbaab8e8c1 276 Gene3D G3DSA:3.40.1410.10 81 250 1.3E-52 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS04735 8d81215ac8a600118a882602b804070a 146 Pfam PF02627 Carboxymuconolactone decarboxylase family 38 122 4.6E-21 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS04735 8d81215ac8a600118a882602b804070a 146 SUPERFAMILY SSF69118 8 127 4.19E-34 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS04735 8d81215ac8a600118a882602b804070a 146 Gene3D G3DSA:1.20.1290.10 8 130 6.5E-35 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS19255 152a2ed2a251bef48d121ecfdd65418e 458 Gene3D G3DSA:3.40.390.10 226 322 9.5E-8 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 LK06_RS19255 152a2ed2a251bef48d121ecfdd65418e 458 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 122 385 7.0E-50 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 LK06_RS19255 152a2ed2a251bef48d121ecfdd65418e 458 SUPERFAMILY SSF55486 248 309 1.4E-5 T 06-07-2017 LK06_RS06380 d1a9d57940a25d38befaf5717ff6ace3 484 Gene3D G3DSA:3.40.710.10 143 483 1.1E-91 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS06380 d1a9d57940a25d38befaf5717ff6ace3 484 Gene3D G3DSA:3.90.1310.10 74 142 2.5E-7 T 06-07-2017 LK06_RS06380 d1a9d57940a25d38befaf5717ff6ace3 484 Pfam PF00905 Penicillin binding protein transpeptidase domain 154 480 4.3E-65 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS06380 d1a9d57940a25d38befaf5717ff6ace3 484 SUPERFAMILY SSF56601 137 483 1.62E-85 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS22505 5311856222946bebbc4dc411dc3eb24e 375 Gene3D G3DSA:1.10.600.10 41 374 2.2E-82 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS22505 5311856222946bebbc4dc411dc3eb24e 375 Pfam PF00348 Polyprenyl synthetase 84 311 5.8E-57 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS22505 5311856222946bebbc4dc411dc3eb24e 375 SUPERFAMILY SSF48576 71 374 1.36E-73 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS22505 5311856222946bebbc4dc411dc3eb24e 375 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 125 139 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS16140 b519793df0dc9619aed6af9b0193f879 334 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 215 8.2E-80 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 LK06_RS16140 b519793df0dc9619aed6af9b0193f879 334 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 6.6E-118 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 LK06_RS16140 b519793df0dc9619aed6af9b0193f879 334 PIRSF PIRSF000267 1 334 2.2E-123 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 LK06_RS10640 3c13478785f5491ecdcc60e214ebc1e1 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 7.9E-17 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS10640 3c13478785f5491ecdcc60e214ebc1e1 348 Pfam PF13377 Periplasmic binding protein-like domain 184 343 2.1E-31 T 06-07-2017 LK06_RS10640 3c13478785f5491ecdcc60e214ebc1e1 348 Gene3D G3DSA:3.40.50.2300 189 324 7.1E-54 T 06-07-2017 LK06_RS10640 3c13478785f5491ecdcc60e214ebc1e1 348 Gene3D G3DSA:1.10.260.40 3 62 6.4E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10640 3c13478785f5491ecdcc60e214ebc1e1 348 SMART SM00354 2 72 3.4E-24 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS10640 3c13478785f5491ecdcc60e214ebc1e1 348 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 06-07-2017 LK06_RS10640 3c13478785f5491ecdcc60e214ebc1e1 348 SUPERFAMILY SSF53822 62 344 1.33E-60 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS10640 3c13478785f5491ecdcc60e214ebc1e1 348 Gene3D G3DSA:3.40.50.2300 63 188 1.6E-41 T 06-07-2017 LK06_RS10640 3c13478785f5491ecdcc60e214ebc1e1 348 SUPERFAMILY SSF47413 2 60 1.15E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10870 f2f4ec01d37788244af26b4c2aabed48 316 Pfam PF14378 PAP2 superfamily 53 240 1.3E-58 T 06-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 LK06_RS23485 6c5136901d0341a2c8e680f4422bafe0 326 SUPERFAMILY SSF51658 16 174 4.56E-5 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS23485 6c5136901d0341a2c8e680f4422bafe0 326 SMART SM00418 253 323 0.0054 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS23485 6c5136901d0341a2c8e680f4422bafe0 326 Gene3D G3DSA:1.10.10.10 260 317 4.7E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23485 6c5136901d0341a2c8e680f4422bafe0 326 Pfam PF12840 Helix-turn-helix domain 260 306 7.3E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23485 6c5136901d0341a2c8e680f4422bafe0 326 SUPERFAMILY SSF46785 251 322 1.85E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 651 749 8.4E-18 T 06-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 SUPERFAMILY SSF81296 42 137 2.6E-18 T 06-07-2017 IPR014756 Immunoglobulin E-set LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 124 750 43.731 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 SMART SM00642 273 627 4.8E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 Gene3D G3DSA:3.20.20.80 270 634 3.2E-93 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 PIRSF PIRSF000463 34 750 1.7E-300 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 Gene3D G3DSA:2.60.40.1180 646 749 1.3E-32 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 148 230 1.9E-18 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 Pfam PF00128 Alpha amylase, catalytic domain 293 362 2.9E-10 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 SUPERFAMILY SSF51011 646 749 2.64E-30 T 06-07-2017 LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 SUPERFAMILY SSF51445 203 640 4.65E-110 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 132 748 1.3E-296 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 Gene3D G3DSA:2.60.40.10 136 244 4.6E-36 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS23620 cc782d5f701596cf6cf64eb452f5a68a 750 Gene3D G3DSA:2.60.40.10 41 129 1.4E-15 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS08530 023e7aed1d7572e29862ff48bbd84023 431 Gene3D G3DSA:3.40.190.10 170 359 2.7E-38 T 06-07-2017 LK06_RS08530 023e7aed1d7572e29862ff48bbd84023 431 Pfam PF01547 Bacterial extracellular solute-binding protein 86 332 2.0E-20 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 LK06_RS08530 023e7aed1d7572e29862ff48bbd84023 431 Gene3D G3DSA:3.40.190.10 85 169 5.7E-12 T 06-07-2017 LK06_RS08530 023e7aed1d7572e29862ff48bbd84023 431 SUPERFAMILY SSF53850 45 398 5.07E-54 T 06-07-2017 LK06_RS29220 457aad588a7b178a01dac4d97f96343a 177 Pfam PF03358 NADPH-dependent FMN reductase 3 143 1.2E-31 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 LK06_RS29220 457aad588a7b178a01dac4d97f96343a 177 Gene3D G3DSA:3.40.50.360 3 171 4.0E-31 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS29220 457aad588a7b178a01dac4d97f96343a 177 SUPERFAMILY SSF52218 3 155 1.55E-30 T 06-07-2017 IPR029039 Flavoprotein-like domain LK06_RS29220 457aad588a7b178a01dac4d97f96343a 177 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 3 171 1.5E-59 T 06-07-2017 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 LK06_RS16040 658f7a2a79347e31616bf1b08e8f7833 288 Gene3D G3DSA:3.40.630.30 9 132 2.2E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS16040 658f7a2a79347e31616bf1b08e8f7833 288 Gene3D G3DSA:3.40.630.30 150 221 8.2E-6 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS16040 658f7a2a79347e31616bf1b08e8f7833 288 Pfam PF13673 Acetyltransferase (GNAT) domain 75 132 4.6E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS16040 658f7a2a79347e31616bf1b08e8f7833 288 SUPERFAMILY SSF55729 11 265 2.82E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS16515 8aa4e5af93db8872ebb118836dbba54e 161 Gene3D G3DSA:3.30.350.10 53 153 1.3E-30 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 LK06_RS16515 8aa4e5af93db8872ebb118836dbba54e 161 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 69 145 1.0E-8 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 LK06_RS16515 8aa4e5af93db8872ebb118836dbba54e 161 SUPERFAMILY SSF55399 62 154 4.18E-25 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 LK06_RS16515 8aa4e5af93db8872ebb118836dbba54e 161 Pfam PF00720 Subtilisin inhibitor-like 67 136 1.1E-8 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 LK06_RS01745 e3df8bef75f78e120c6aa9dacf79fecf 477 Gene3D G3DSA:3.40.50.720 317 455 1.5E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01745 e3df8bef75f78e120c6aa9dacf79fecf 477 Gene3D G3DSA:3.40.50.720 124 228 1.5E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01745 e3df8bef75f78e120c6aa9dacf79fecf 477 Pfam PF00106 short chain dehydrogenase 142 233 8.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS01745 e3df8bef75f78e120c6aa9dacf79fecf 477 SUPERFAMILY SSF51735 138 235 1.9E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01745 e3df8bef75f78e120c6aa9dacf79fecf 477 SUPERFAMILY SSF51735 320 433 1.9E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS26120 7c6e2373069b51438edffe81d2aaf47f 426 SUPERFAMILY SSF53850 42 419 7.83E-70 T 06-07-2017 LK06_RS26120 7c6e2373069b51438edffe81d2aaf47f 426 Gene3D G3DSA:3.40.190.10 167 355 5.6E-34 T 06-07-2017 LK06_RS26120 7c6e2373069b51438edffe81d2aaf47f 426 Gene3D G3DSA:3.40.190.10 41 166 4.3E-26 T 06-07-2017 LK06_RS26120 7c6e2373069b51438edffe81d2aaf47f 426 Pfam PF01547 Bacterial extracellular solute-binding protein 51 337 2.3E-42 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 LK06_RS12410 1c39f3ee1d20878fb9adac6586d39bb2 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.8E-64 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 LK06_RS12410 1c39f3ee1d20878fb9adac6586d39bb2 156 Gene3D G3DSA:1.10.455.10 8 156 1.5E-60 T 06-07-2017 IPR023798 Ribosomal protein S7 domain LK06_RS12410 1c39f3ee1d20878fb9adac6586d39bb2 156 SUPERFAMILY SSF47973 1 149 1.7E-57 T 06-07-2017 IPR023798 Ribosomal protein S7 domain LK06_RS12410 1c39f3ee1d20878fb9adac6586d39bb2 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 7.9E-60 T 06-07-2017 IPR023798 Ribosomal protein S7 domain LK06_RS12410 1c39f3ee1d20878fb9adac6586d39bb2 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.7 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 LK06_RS12410 1c39f3ee1d20878fb9adac6586d39bb2 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 06-07-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12410 1c39f3ee1d20878fb9adac6586d39bb2 156 PIRSF PIRSF002122 7 156 7.0E-56 T 06-07-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 SUPERFAMILY SSF47413 1 59 2.34E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 4.7E-6 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 4.7E-6 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 Gene3D G3DSA:3.40.50.2300 173 310 3.2E-46 T 06-07-2017 LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 Gene3D G3DSA:3.40.50.2300 54 172 3.6E-43 T 06-07-2017 LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.3E-19 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 Gene3D G3DSA:1.10.260.40 2 53 9.8E-26 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 06-07-2017 LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 SMART SM00354 1 71 2.0E-34 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 SUPERFAMILY SSF53822 62 331 6.39E-76 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS32025 465183632dae54d202a2dc62662fc1fc 338 Pfam PF13377 Periplasmic binding protein-like domain 168 327 2.6E-35 T 06-07-2017 LK06_RS21820 0d49eca1e960345fe1e4e57b5b3c158f 344 Gene3D G3DSA:1.10.3720.10 121 340 1.3E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21820 0d49eca1e960345fe1e4e57b5b3c158f 344 SUPERFAMILY SSF161098 123 328 1.02E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21820 0d49eca1e960345fe1e4e57b5b3c158f 344 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 145 342 2.9E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21820 0d49eca1e960345fe1e4e57b5b3c158f 344 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 35 78 3.5E-8 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LK06_RS05685 8c4c21c2dbebcc83bce75a44bf8fd653 216 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 20 183 1.3E-30 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 LK06_RS05685 8c4c21c2dbebcc83bce75a44bf8fd653 216 PIRSF PIRSF019345 5 216 1.4E-54 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 LK06_RS05685 8c4c21c2dbebcc83bce75a44bf8fd653 216 Pfam PF04079 Segregation and condensation complex subunit ScpB 23 180 3.5E-56 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 LK06_RS05685 8c4c21c2dbebcc83bce75a44bf8fd653 216 SUPERFAMILY SSF46785 98 171 3.29E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05685 8c4c21c2dbebcc83bce75a44bf8fd653 216 SUPERFAMILY SSF46785 20 93 1.32E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05685 8c4c21c2dbebcc83bce75a44bf8fd653 216 Gene3D G3DSA:1.10.10.10 98 171 2.6E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05685 8c4c21c2dbebcc83bce75a44bf8fd653 216 Gene3D G3DSA:1.10.10.10 20 94 3.3E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09500 ed14c66f6896cc5e7622229fe404d414 338 Gene3D G3DSA:1.10.10.10 1 84 3.4E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09500 ed14c66f6896cc5e7622229fe404d414 338 Pfam PF01628 HrcA protein C terminal domain 103 321 1.3E-61 T 06-07-2017 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 LK06_RS09500 ed14c66f6896cc5e7622229fe404d414 338 PIRSF PIRSF005485 1 338 7.6E-102 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 LK06_RS09500 ed14c66f6896cc5e7622229fe404d414 338 SUPERFAMILY SSF46785 1 82 7.44E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09500 ed14c66f6896cc5e7622229fe404d414 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 5.3E-103 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 LK06_RS09500 ed14c66f6896cc5e7622229fe404d414 338 Gene3D G3DSA:3.30.450.40 176 337 3.1E-43 T 06-07-2017 IPR029016 GAF domain-like LK06_RS09500 ed14c66f6896cc5e7622229fe404d414 338 SUPERFAMILY SSF55781 71 336 7.85E-58 T 06-07-2017 IPR029016 GAF domain-like LK06_RS09500 ed14c66f6896cc5e7622229fe404d414 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 28.639 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 LK06_RS27010 467ed5698800148f545faed2bd0d259d 281 Pfam PF05675 Protein of unknown function (DUF817) 15 247 3.1E-89 T 06-07-2017 IPR008535 Protein of unknown function DUF817 LK06_RS27010 467ed5698800148f545faed2bd0d259d 281 PIRSF PIRSF009141 3 260 3.6E-85 T 06-07-2017 IPR008535 Protein of unknown function DUF817 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 Gene3D G3DSA:1.10.490.10 61 189 4.5E-39 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 SUPERFAMILY SSF63380 197 292 1.43E-23 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 Pfam PF00175 Oxidoreductase NAD-binding domain 305 397 1.4E-11 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 Gene3D G3DSA:3.40.50.80 297 417 3.0E-26 T 06-07-2017 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 243 250 6.2E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 303 322 6.2E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 328 337 6.2E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 SUPERFAMILY SSF46458 58 186 1.08E-31 T 06-07-2017 IPR009050 Globin-like LK06_RS16050 ab953ad844d299b1001aa71670439963 426 Pfam PF00970 Oxidoreductase FAD-binding domain 201 292 4.8E-12 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 SUPERFAMILY SSF52343 298 417 3.8E-26 T 06-07-2017 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 PRINTS PR00410 Phenol hydroxylase reductase family signature 225 237 2.1E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 PRINTS PR00410 Phenol hydroxylase reductase family signature 303 322 2.1E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 PRINTS PR00410 Phenol hydroxylase reductase family signature 386 394 2.1E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 Gene3D G3DSA:2.40.30.10 193 291 4.2E-24 T 06-07-2017 LK06_RS16050 ab953ad844d299b1001aa71670439963 426 Pfam PF00042 Globin 60 152 4.4E-8 T 06-07-2017 IPR000971 Globin GO:0019825|GO:0020037 LK06_RS22485 40240c7a835b185611df3d413a815eed 86 SUPERFAMILY SSF57850 2 85 3.77E-23 T 06-07-2017 LK06_RS22485 40240c7a835b185611df3d413a815eed 86 Gene3D G3DSA:3.30.40.10 2 84 2.3E-21 T 06-07-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type LK06_RS22485 40240c7a835b185611df3d413a815eed 86 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 34 82 1.5E-9 T 06-07-2017 IPR001607 Zinc finger, UBP-type GO:0008270 LK06_RS29925 3f509f1f7de7a1d7b87071bed65854c9 249 SUPERFAMILY SSF51735 4 244 8.74E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29925 3f509f1f7de7a1d7b87071bed65854c9 249 Pfam PF00106 short chain dehydrogenase 11 181 1.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29925 3f509f1f7de7a1d7b87071bed65854c9 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS29925 3f509f1f7de7a1d7b87071bed65854c9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.4E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29925 3f509f1f7de7a1d7b87071bed65854c9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.4E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29925 3f509f1f7de7a1d7b87071bed65854c9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.4E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29925 3f509f1f7de7a1d7b87071bed65854c9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.4E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS29925 3f509f1f7de7a1d7b87071bed65854c9 249 Gene3D G3DSA:3.40.50.720 4 244 4.3E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS14495 8836f380ec246dcddbe0755ff53e90f1 220 Pfam PF16702 Domain of unknown function (DUF5063) 13 173 2.0E-43 T 06-07-2017 IPR032025 Protein of unknown function DUF5063 LK06_RS23255 26d30c224e172051321562f835764b26 219 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 26 146 1.6E-15 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily LK06_RS23255 26d30c224e172051321562f835764b26 219 SUPERFAMILY SSF52788 182 210 3.14E-23 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily LK06_RS23255 26d30c224e172051321562f835764b26 219 SUPERFAMILY SSF52788 22 145 3.14E-23 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily LK06_RS23255 26d30c224e172051321562f835764b26 219 SMART SM00226 24 211 2.3E-7 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily LK06_RS23255 26d30c224e172051321562f835764b26 219 Gene3D G3DSA:3.40.50.270 175 212 7.3E-31 T 06-07-2017 LK06_RS23255 26d30c224e172051321562f835764b26 219 Gene3D G3DSA:3.40.50.270 24 136 7.3E-31 T 06-07-2017 LK06_RS07250 9da8e9d314e74d28be0a164043a9d589 406 SUPERFAMILY SSF57716 371 405 1.71E-8 T 06-07-2017 LK06_RS07250 9da8e9d314e74d28be0a164043a9d589 406 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 369 404 2.5E-12 T 06-07-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 LK06_RS07250 9da8e9d314e74d28be0a164043a9d589 406 PRINTS PR00618 DksA/TraR zinc finger signature 374 385 9.8E-5 T 06-07-2017 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria LK06_RS07250 9da8e9d314e74d28be0a164043a9d589 406 PRINTS PR00618 DksA/TraR zinc finger signature 386 398 9.8E-5 T 06-07-2017 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria LK06_RS07250 9da8e9d314e74d28be0a164043a9d589 406 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 374 398 - T 06-07-2017 IPR020458 Zinc finger, DksA/TraR C4-type conserved site LK06_RS07250 9da8e9d314e74d28be0a164043a9d589 406 SUPERFAMILY SSF109635 276 370 6.54E-10 T 06-07-2017 LK06_RS29740 f3ed200fea24e06b3d3891b03f04c3a1 617 Gene3D G3DSA:2.60.40.10 383 464 3.7E-11 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS29740 f3ed200fea24e06b3d3891b03f04c3a1 617 Pfam PF05345 Putative Ig domain 415 455 3.0E-12 T 06-07-2017 IPR008009 Putative Ig LK06_RS29740 f3ed200fea24e06b3d3891b03f04c3a1 617 SUPERFAMILY SSF49313 384 463 7.85E-13 T 06-07-2017 IPR015919 Cadherin-like GO:0005509|GO:0016020 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 574 1.7E-280 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 SUPERFAMILY SSF53067 4 160 2.3E-58 T 06-07-2017 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Pfam PF00012 Hsp70 protein 80 574 1.1E-221 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Pfam PF00012 Hsp70 protein 4 78 6.4E-29 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Gene3D G3DSA:3.30.420.40 4 38 1.5E-56 T 06-07-2017 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Gene3D G3DSA:3.30.420.40 101 168 1.5E-56 T 06-07-2017 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 SUPERFAMILY SSF53067 161 353 1.73E-65 T 06-07-2017 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Gene3D G3DSA:2.60.34.10 361 503 2.0E-72 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 PRINTS PR00301 70kDa heat shock protein signature 114 134 3.4E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 PRINTS PR00301 70kDa heat shock protein signature 172 182 3.4E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 PRINTS PR00301 70kDa heat shock protein signature 304 320 3.4E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 PRINTS PR00301 70kDa heat shock protein signature 54 62 3.4E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 PRINTS PR00301 70kDa heat shock protein signature 336 356 3.4E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.4E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 PRINTS PR00301 70kDa heat shock protein signature 440 456 3.4E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 PRINTS PR00301 70kDa heat shock protein signature 31 43 3.4E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 PRINTS PR00301 70kDa heat shock protein signature 359 378 3.4E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Gene3D G3DSA:3.30.420.40 169 199 1.0E-33 T 06-07-2017 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Gene3D G3DSA:3.30.420.40 289 331 1.0E-33 T 06-07-2017 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Gene3D G3DSA:3.30.30.30 39 100 3.8E-17 T 06-07-2017 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 601 36.298 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Gene3D G3DSA:1.20.1270.10 504 574 2.9E-28 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 Gene3D G3DSA:3.90.640.10 200 285 1.5E-31 T 06-07-2017 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LK06_RS14760 4916b38c838982293cfaeaa6b5943832 608 SUPERFAMILY SSF100920 355 511 1.2E-59 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 LK06_RS12325 b4014f8307d09acbec546692ccefc61b 152 Pfam PF01230 HIT domain 20 109 1.7E-11 T 06-07-2017 IPR001310 Histidine triad (HIT) protein LK06_RS12325 b4014f8307d09acbec546692ccefc61b 152 Gene3D G3DSA:3.30.428.10 11 120 6.0E-22 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS12325 b4014f8307d09acbec546692ccefc61b 152 SUPERFAMILY SSF54197 11 116 2.63E-21 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS02160 0308f385a1e44c965e3c25bd5decf672 417 Pfam PF09992 Phosphodiester glycosidase 240 414 3.6E-25 T 06-07-2017 IPR018711 Phosphodiester glycosidase LK06_RS30260 ba6a81a72b0a2207333506f7ac758083 468 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 55 456 2.3E-146 T 06-07-2017 IPR018721 Protein of unknown function DUF2252 LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SUPERFAMILY SSF51126 285 475 8.03E-6 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 TIGRFAM TIGR01376 POMP_repeat: chlamydial polymorphic outer membrane protein repeat 218 235 0.0011 T 06-07-2017 IPR003368 Polymorphic outer membrane protein repeat LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SMART SM00710 396 436 1700.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SMART SM00710 159 180 2200.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SMART SM00710 361 388 3800.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SMART SM00710 333 357 840.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SMART SM00710 242 262 820.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SMART SM00710 187 209 5400.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SMART SM00710 214 235 100.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SMART SM00710 124 152 3100.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SMART SM00710 299 323 1600.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 SUPERFAMILY SSF51126 20 317 4.57E-16 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 Gene3D G3DSA:2.160.20.10 21 284 9.2E-19 T 06-07-2017 IPR012334 Pectin lyase fold LK06_RS02915 f5bf2a7e8cf355bde0887a0bca7b93b6 484 Gene3D G3DSA:2.160.20.10 298 465 6.2E-6 T 06-07-2017 IPR012334 Pectin lyase fold LK06_RS28705 d48b60e1a66791e836d681475da1557d 290 Gene3D G3DSA:3.90.550.10 6 225 7.8E-25 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS28705 d48b60e1a66791e836d681475da1557d 290 Pfam PF00535 Glycosyl transferase family 2 6 144 2.0E-10 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS28705 d48b60e1a66791e836d681475da1557d 290 SUPERFAMILY SSF53448 4 243 6.38E-37 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS02455 a6bd86be4f3b6bada2f4e5c8aadd8267 181 Pfam PF00872 Transposase, Mutator family 1 150 6.2E-27 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 LK06_RS02455 a6bd86be4f3b6bada2f4e5c8aadd8267 181 ProSitePatterns PS01007 Transposases, Mutator family, signature. 5 29 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 LK06_RS15180 8550259314d2e63114a8941487e67b8a 115 Pfam PF13601 Winged helix DNA-binding domain 21 98 6.3E-18 T 06-07-2017 IPR027395 Winged helix DNA-binding domain LK06_RS15180 8550259314d2e63114a8941487e67b8a 115 Gene3D G3DSA:1.10.10.10 12 99 8.3E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15180 8550259314d2e63114a8941487e67b8a 115 SUPERFAMILY SSF46785 13 94 4.43E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30335 5f6f3e268533d9f1ff66028252ebe0b8 278 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 271 17.419 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 LK06_RS30335 5f6f3e268533d9f1ff66028252ebe0b8 278 Pfam PF02673 Bacitracin resistance protein BacA 9 265 3.8E-73 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 LK06_RS30335 5f6f3e268533d9f1ff66028252ebe0b8 278 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 264 7.7E-73 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 LK06_RS21170 e1dba6861c7cd9781881e69b1737a579 607 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 271 279 - T 06-07-2017 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 LK06_RS21170 e1dba6861c7cd9781881e69b1737a579 607 SUPERFAMILY SSF68923 11 246 2.82E-97 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 LK06_RS21170 e1dba6861c7cd9781881e69b1737a579 607 Gene3D G3DSA:3.90.228.20 247 316 2.4E-33 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 LK06_RS21170 e1dba6861c7cd9781881e69b1737a579 607 Gene3D G3DSA:3.90.228.20 333 606 7.3E-103 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 LK06_RS21170 e1dba6861c7cd9781881e69b1737a579 607 Pfam PF00821 Phosphoenolpyruvate carboxykinase 20 606 9.2E-287 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 LK06_RS21170 e1dba6861c7cd9781881e69b1737a579 607 Gene3D G3DSA:3.40.449.10 10 246 1.7E-99 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 LK06_RS21170 e1dba6861c7cd9781881e69b1737a579 607 PIRSF PIRSF001348 3 607 3.3E-285 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 LK06_RS21170 e1dba6861c7cd9781881e69b1737a579 607 SUPERFAMILY SSF53795 247 606 5.26E-160 T 06-07-2017 LK06_RS21170 e1dba6861c7cd9781881e69b1737a579 607 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 9 607 52.65 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 LK06_RS04905 010333cd11ed13aa2ada9d02b6161f67 306 SMART SM00279 185 220 1.7E-11 T 06-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 LK06_RS04905 010333cd11ed13aa2ada9d02b6161f67 306 Gene3D G3DSA:1.10.150.20 181 251 6.8E-19 T 06-07-2017 LK06_RS04905 010333cd11ed13aa2ada9d02b6161f67 306 SMART SM00475 3 277 4.1E-80 T 06-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 LK06_RS04905 010333cd11ed13aa2ada9d02b6161f67 306 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 187 268 1.6E-17 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 LK06_RS04905 010333cd11ed13aa2ada9d02b6161f67 306 SUPERFAMILY SSF88723 4 165 1.67E-38 T 06-07-2017 IPR029060 PIN domain-like LK06_RS04905 010333cd11ed13aa2ada9d02b6161f67 306 Gene3D G3DSA:3.40.50.1010 3 180 2.8E-48 T 06-07-2017 IPR029060 PIN domain-like LK06_RS04905 010333cd11ed13aa2ada9d02b6161f67 306 SUPERFAMILY SSF47807 188 297 4.93E-19 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 LK06_RS04905 010333cd11ed13aa2ada9d02b6161f67 306 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 182 2.4E-47 T 06-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 LK06_RS18735 23c4ce91536c0ef9b99bb3210ba318fa 221 SMART SM00943 29 210 1.1E-34 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal LK06_RS18735 23c4ce91536c0ef9b99bb3210ba318fa 221 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 29 202 7.4E-23 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 06-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 8.1E-165 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 SUPERFAMILY SSF51621 1 74 1.47E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 SUPERFAMILY SSF51621 154 337 1.47E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 SUPERFAMILY SSF50800 70 164 1.74E-26 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 Gene3D G3DSA:3.20.20.60 167 322 6.6E-105 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 Gene3D G3DSA:3.20.20.60 2 72 6.6E-105 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 1.8E-26 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 Gene3D G3DSA:2.40.33.10 73 166 9.5E-30 T 06-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 1.2E-127 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 SUPERFAMILY SSF52935 320 470 8.37E-37 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 Gene3D G3DSA:3.40.1380.20 323 469 3.0E-41 T 06-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 PRINTS PR01050 Pyruvate kinase family signature 241 265 6.5E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 PRINTS PR01050 Pyruvate kinase family signature 214 240 6.5E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 PRINTS PR01050 Pyruvate kinase family signature 291 309 6.5E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 PRINTS PR01050 Pyruvate kinase family signature 266 290 6.5E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 PRINTS PR01050 Pyruvate kinase family signature 310 326 6.5E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 PRINTS PR01050 Pyruvate kinase family signature 184 198 6.5E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS23540 d26307521f0c8bcfa1ea392f61bab452 474 PRINTS PR01050 Pyruvate kinase family signature 59 75 6.5E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LK06_RS15970 69e413bb65bd18082a87b9e0941ea26f 514 Pfam PF09594 Protein of unknown function (DUF2029) 127 366 1.8E-8 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 LK06_RS15970 69e413bb65bd18082a87b9e0941ea26f 514 PIRSF PIRSF010361 22 479 4.9E-147 T 06-07-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 Pfam PF14759 Reductase C-terminal 334 419 2.0E-15 T 06-07-2017 IPR028202 Reductase, C-terminal LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 1.3E-14 T 06-07-2017 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 241 255 1.3E-14 T 06-07-2017 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.3E-14 T 06-07-2017 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 285 292 1.3E-14 T 06-07-2017 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 SUPERFAMILY SSF51905 154 324 8.01E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 1.0E-24 T 06-07-2017 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 1.0E-24 T 06-07-2017 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.0E-24 T 06-07-2017 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 1.0E-24 T 06-07-2017 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.0E-24 T 06-07-2017 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 313 1.0E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 SUPERFAMILY SSF51905 6 199 2.13E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 Gene3D G3DSA:3.50.50.60 112 324 3.2E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 Gene3D G3DSA:3.30.390.30 334 420 1.5E-29 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 SUPERFAMILY SSF55424 327 420 3.16E-26 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 LK06_RS09185 d5e901f3ffa2300b026c486ed21c4795 421 Gene3D G3DSA:3.50.50.60 5 111 4.0E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09390 e8e49689f80993a4b2a72d44531548ce 440 TIGRFAM TIGR03356 BGL: beta-galactosidase 15 432 1.4E-154 T 06-07-2017 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 LK06_RS09390 e8e49689f80993a4b2a72d44531548ce 440 Pfam PF00232 Glycosyl hydrolase family 1 14 438 6.5E-125 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS09390 e8e49689f80993a4b2a72d44531548ce 440 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 19 33 - T 06-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site LK06_RS09390 e8e49689f80993a4b2a72d44531548ce 440 SUPERFAMILY SSF51445 14 438 1.07E-142 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS09390 e8e49689f80993a4b2a72d44531548ce 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 403 8.7E-22 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS09390 e8e49689f80993a4b2a72d44531548ce 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 276 290 8.7E-22 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS09390 e8e49689f80993a4b2a72d44531548ce 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 365 376 8.7E-22 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS09390 e8e49689f80993a4b2a72d44531548ce 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 422 8.7E-22 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS09390 e8e49689f80993a4b2a72d44531548ce 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 351 359 8.7E-22 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 LK06_RS09390 e8e49689f80993a4b2a72d44531548ce 440 Gene3D G3DSA:3.20.20.80 14 439 6.7E-140 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS20925 5f1d233c9a9fd00a41293192413c8459 301 Pfam PF13560 Helix-turn-helix domain 21 101 5.3E-18 T 06-07-2017 LK06_RS20925 5f1d233c9a9fd00a41293192413c8459 301 SUPERFAMILY SSF47413 45 96 4.74E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS20925 5f1d233c9a9fd00a41293192413c8459 301 Gene3D G3DSA:1.10.260.40 16 97 1.3E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS20925 5f1d233c9a9fd00a41293192413c8459 301 SMART SM00530 25 98 6.3E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS22150 1c5a267eeeb4045d75f5863e31e7814c 481 Gene3D G3DSA:3.40.390.10 338 446 4.8E-4 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 LK06_RS22150 1c5a267eeeb4045d75f5863e31e7814c 481 Pfam PF11350 Protein of unknown function (DUF3152) 297 479 5.9E-61 T 06-07-2017 IPR022603 Domain of unknown function DUF3152 LK06_RS22150 1c5a267eeeb4045d75f5863e31e7814c 481 SUPERFAMILY SSF55486 306 464 6.55E-14 T 06-07-2017 LK06_RS30930 f8eda2c71fcdb18432e36bca90011562 152 SMART SM00100 7 128 7.0E-5 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain LK06_RS30930 f8eda2c71fcdb18432e36bca90011562 152 SUPERFAMILY SSF51206 3 132 6.28E-21 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like LK06_RS30930 f8eda2c71fcdb18432e36bca90011562 152 Gene3D G3DSA:2.60.120.10 3 132 4.4E-17 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS30930 f8eda2c71fcdb18432e36bca90011562 152 Pfam PF00027 Cyclic nucleotide-binding domain 26 112 1.2E-10 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain LK06_RS00715 33b06afb26fac5cabb0b63db67206e73 394 Gene3D G3DSA:1.10.260.40 5 71 1.6E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS00715 33b06afb26fac5cabb0b63db67206e73 394 Pfam PF13560 Helix-turn-helix domain 10 65 4.3E-7 T 06-07-2017 LK06_RS00715 33b06afb26fac5cabb0b63db67206e73 394 SMART SM00530 12 67 3.0E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS00715 33b06afb26fac5cabb0b63db67206e73 394 SUPERFAMILY SSF47413 3 69 1.97E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS08460 5232cc35dc96fe6374a7f678976863fe 422 Gene3D G3DSA:3.30.565.10 301 409 1.1E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS08460 5232cc35dc96fe6374a7f678976863fe 422 SUPERFAMILY SSF55874 301 406 1.1E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS08460 5232cc35dc96fe6374a7f678976863fe 422 Pfam PF07730 Histidine kinase 214 280 5.8E-16 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS08460 5232cc35dc96fe6374a7f678976863fe 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 406 2.9E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 6.9E-40 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Gene3D G3DSA:3.40.50.20 1 130 4.9E-46 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1123 0.0 T 06-07-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 SMART SM00878 339 446 6.6E-56 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 SUPERFAMILY SSF51230 1047 1123 2.62E-16 T 06-07-2017 IPR011053 Single hybrid motif LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 SUPERFAMILY SSF51569 521 828 2.75E-75 T 06-07-2017 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 SUPERFAMILY SSF51246 334 451 9.94E-38 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 SUPERFAMILY SSF52440 1 112 6.98E-41 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 SUPERFAMILY SSF89000 825 990 7.85E-41 T 06-07-2017 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 SUPERFAMILY SSF56059 84 362 7.6E-72 T 06-07-2017 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Pfam PF00682 HMGL-like 525 794 4.1E-28 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Gene3D G3DSA:3.30.470.20 205 451 3.2E-100 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 321 7.0E-69 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Gene3D G3DSA:3.20.20.70 502 811 5.1E-126 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Gene3D G3DSA:3.30.1490.20 131 201 1.5E-25 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Pfam PF02436 Conserved carboxylase domain 820 1007 1.9E-54 T 06-07-2017 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Pfam PF02785 Biotin carboxylase C-terminal domain 339 447 8.6E-35 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Gene3D G3DSA:2.40.50.100 1049 1123 2.7E-20 T 06-07-2017 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Gene3D G3DSA:3.10.600.10 958 1045 5.6E-31 T 06-07-2017 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 PIRSF PIRSF001594 1 1124 0.0 T 06-07-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 LK06_RS00665 4d6f062821b6ef97a4626fa1f1aad811 1124 Pfam PF00364 Biotin-requiring enzyme 1065 1123 2.5E-14 T 06-07-2017 IPR000089 Biotin/lipoyl attachment LK06_RS22005 27e359c1633cd681847fa3ad41f3d29e 210 SUPERFAMILY SSF48150 14 192 1.65E-68 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS22005 27e359c1633cd681847fa3ad41f3d29e 210 Pfam PF03352 Methyladenine glycosylase 18 190 1.3E-65 T 06-07-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 LK06_RS22005 27e359c1633cd681847fa3ad41f3d29e 210 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 15 190 5.4E-71 T 06-07-2017 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 LK06_RS22005 27e359c1633cd681847fa3ad41f3d29e 210 Gene3D G3DSA:1.10.340.30 15 192 4.5E-71 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS26090 779602c03df7910f9b871449a8f20302 270 Pfam PF07848 PaaX-like protein 10 78 1.9E-23 T 06-07-2017 IPR012906 PaaX-like, N-terminal LK06_RS26090 779602c03df7910f9b871449a8f20302 270 Pfam PF08223 PaaX-like protein C-terminal domain 96 262 1.5E-52 T 06-07-2017 IPR013225 PaaX-like, C-terminal LK06_RS26090 779602c03df7910f9b871449a8f20302 270 Gene3D G3DSA:1.10.10.10 35 83 8.7E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26090 779602c03df7910f9b871449a8f20302 270 PIRSF PIRSF020623 2 269 8.9E-92 T 06-07-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 Pfam PF02274 Amidinotransferase 17 404 1.4E-89 T 06-07-2017 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 PIRSF PIRSF006356 1 407 2.2E-153 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 Hamap MF_00242 Arginine deiminase [arcA]. 1 407 42.662 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 Gene3D G3DSA:3.75.10.10 2 66 3.4E-128 T 06-07-2017 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 Gene3D G3DSA:3.75.10.10 151 407 3.4E-128 T 06-07-2017 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 PRINTS PR01466 Bacterial arginine deiminase signature 386 404 1.9E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 PRINTS PR01466 Bacterial arginine deiminase signature 363 377 1.9E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 PRINTS PR01466 Bacterial arginine deiminase signature 343 360 1.9E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 1.9E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 PRINTS PR01466 Bacterial arginine deiminase signature 1 20 1.9E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 1.9E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS26060 c01cdb885498a6585b11eb3a7bf1ba14 407 SUPERFAMILY SSF55909 2 405 5.3E-126 T 06-07-2017 LK06_RS32020 e7ff6ef0ad2e4ba1c66c34a2b3ea0e71 508 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS32020 e7ff6ef0ad2e4ba1c66c34a2b3ea0e71 508 Gene3D G3DSA:3.40.50.300 5 228 1.2E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32020 e7ff6ef0ad2e4ba1c66c34a2b3ea0e71 508 SUPERFAMILY SSF52540 7 228 1.85E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32020 e7ff6ef0ad2e4ba1c66c34a2b3ea0e71 508 Gene3D G3DSA:3.40.50.300 267 491 8.4E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32020 e7ff6ef0ad2e4ba1c66c34a2b3ea0e71 508 Pfam PF00005 ABC transporter 23 172 2.0E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS32020 e7ff6ef0ad2e4ba1c66c34a2b3ea0e71 508 Pfam PF00005 ABC transporter 271 424 3.0E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS32020 e7ff6ef0ad2e4ba1c66c34a2b3ea0e71 508 SMART SM00382 32 220 1.1E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS32020 e7ff6ef0ad2e4ba1c66c34a2b3ea0e71 508 SMART SM00382 279 473 1.2E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS32020 e7ff6ef0ad2e4ba1c66c34a2b3ea0e71 508 SUPERFAMILY SSF52540 269 486 1.18E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22250 42c711fcb1b697ef1071767d60b8ab7b 456 SUPERFAMILY SSF56112 95 158 2.76E-21 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS22250 42c711fcb1b697ef1071767d60b8ab7b 456 SUPERFAMILY SSF56112 195 310 2.76E-21 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS22250 42c711fcb1b697ef1071767d60b8ab7b 456 Pfam PF03109 ABC1 family 113 227 8.9E-30 T 06-07-2017 IPR004147 UbiB domain LK06_RS23010 d523ace86e1202233fdc343f0cbc74c2 187 Pfam PF00293 NUDIX domain 10 133 3.1E-21 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS23010 d523ace86e1202233fdc343f0cbc74c2 187 Gene3D G3DSA:3.90.79.10 9 137 1.2E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS23010 d523ace86e1202233fdc343f0cbc74c2 187 PRINTS PR00502 NUDIX hydrolase family signature 34 48 3.7E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS23010 d523ace86e1202233fdc343f0cbc74c2 187 PRINTS PR00502 NUDIX hydrolase family signature 48 63 3.7E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS23010 d523ace86e1202233fdc343f0cbc74c2 187 SUPERFAMILY SSF55811 9 135 5.96E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS23010 d523ace86e1202233fdc343f0cbc74c2 187 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS02540 dd75d59105569b5837edc4f8232d94c4 357 SUPERFAMILY SSF69118 20 188 6.67E-29 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS02540 dd75d59105569b5837edc4f8232d94c4 357 Pfam PF02627 Carboxymuconolactone decarboxylase family 64 141 2.4E-7 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS02540 dd75d59105569b5837edc4f8232d94c4 357 Gene3D G3DSA:1.20.1290.10 158 188 7.0E-22 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS02540 dd75d59105569b5837edc4f8232d94c4 357 Gene3D G3DSA:1.20.1290.10 23 124 7.0E-22 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS02540 dd75d59105569b5837edc4f8232d94c4 357 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 79 110 9.6E-9 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS18980 3543437ca09a361e6e1bbe8f53622aea 372 Pfam PF00296 Luciferase-like monooxygenase 2 328 4.0E-42 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS18980 3543437ca09a361e6e1bbe8f53622aea 372 Gene3D G3DSA:3.20.20.30 1 365 2.6E-75 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS18980 3543437ca09a361e6e1bbe8f53622aea 372 SUPERFAMILY SSF51679 2 357 9.29E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS17250 b361ef5324c2cc7fdd382464658edcee 171 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 7 168 1.7E-16 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase LK06_RS17250 b361ef5324c2cc7fdd382464658edcee 171 Gene3D G3DSA:3.30.530.20 7 138 9.2E-11 T 06-07-2017 IPR023393 START-like domain LK06_RS17250 b361ef5324c2cc7fdd382464658edcee 171 SUPERFAMILY SSF55961 8 168 3.39E-17 T 06-07-2017 LK06_RS22365 769023071a9aa533773b26d6731a2752 240 Pfam PF13398 Peptidase M50B-like 30 232 1.1E-62 T 06-07-2017 LK06_RS26770 362e45bb81ce497e2c5b30622f7f2a2f 136 Pfam PF05331 Protein of unknown function (DUF742) 15 124 1.2E-20 T 06-07-2017 IPR007995 Protein of unknown function DUF742 LK06_RS02420 410ab7c9a6d0b9a0250fdd422d63d795 107 Pfam PF13006 Insertion element 4 transposase N-terminal 19 107 4.5E-29 T 06-07-2017 IPR024473 Transposase, IS4, N-terminal LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 SUPERFAMILY SSF53335 153 306 3.13E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 SUPERFAMILY SSF53335 16 54 3.13E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 SUPERFAMILY SSF53335 89 124 3.13E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 34 48 2.2E-23 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 263 281 2.2E-23 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 101 121 2.2E-23 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 244 261 2.2E-23 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 286 306 2.2E-23 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 Gene3D G3DSA:3.40.50.150 13 307 2.5E-55 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 39 44 - T 06-07-2017 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 LK06_RS19555 ba1f8f86af0f69be938152220843e7bd 333 Pfam PF01555 DNA methylase 35 298 7.9E-35 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 LK06_RS11135 1c61e5874ba0f9738f3971bf92debcb1 266 Pfam PF06182 ABC-2 family transporter protein 43 265 2.9E-18 T 06-07-2017 IPR010390 Protein of unknown function DUF990 LK06_RS12710 df4786af17045feb3a13e3951a046d4f 135 Pfam PF01638 HxlR-like helix-turn-helix 24 115 5.0E-23 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type LK06_RS12710 df4786af17045feb3a13e3951a046d4f 135 SUPERFAMILY SSF46785 13 126 5.3E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12710 df4786af17045feb3a13e3951a046d4f 135 Gene3D G3DSA:1.10.10.10 6 126 2.3E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00265 156460011a9a4a2b5dc6c05002e248ab 297 Pfam PF00582 Universal stress protein family 5 145 1.1E-18 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS00265 156460011a9a4a2b5dc6c05002e248ab 297 Pfam PF00582 Universal stress protein family 156 294 1.6E-17 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS00265 156460011a9a4a2b5dc6c05002e248ab 297 SUPERFAMILY SSF52402 157 294 2.76E-20 T 06-07-2017 LK06_RS00265 156460011a9a4a2b5dc6c05002e248ab 297 PRINTS PR01438 Universal stress protein signature 254 266 1.4E-9 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00265 156460011a9a4a2b5dc6c05002e248ab 297 PRINTS PR01438 Universal stress protein signature 272 294 1.4E-9 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00265 156460011a9a4a2b5dc6c05002e248ab 297 PRINTS PR01438 Universal stress protein signature 2 20 1.4E-9 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00265 156460011a9a4a2b5dc6c05002e248ab 297 Gene3D G3DSA:3.40.50.620 155 294 1.6E-22 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS00265 156460011a9a4a2b5dc6c05002e248ab 297 Gene3D G3DSA:3.40.50.620 4 145 8.0E-24 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS00265 156460011a9a4a2b5dc6c05002e248ab 297 SUPERFAMILY SSF52402 5 148 3.77E-22 T 06-07-2017 LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 SMART SM00642 2 688 9.6E-7 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 Gene3D G3DSA:3.20.20.80 2 91 4.3E-64 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 Gene3D G3DSA:3.20.20.80 485 524 4.3E-64 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 Gene3D G3DSA:3.20.20.80 621 720 4.3E-64 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 Gene3D G3DSA:3.20.20.80 223 295 4.3E-64 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 Pfam PF00128 Alpha amylase, catalytic domain 24 97 1.3E-13 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 Gene3D G3DSA:1.10.10.470 525 609 4.6E-18 T 06-07-2017 IPR013797 Maltooligosyl trehalose synthase, N-terminal MetaCyc: PWY-2661 LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 Gene3D G3DSA:3.30.1590.10 92 207 1.5E-35 T 06-07-2017 LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 2 779 1.4E-260 T 06-07-2017 IPR012767 Malto-oligosyltrehalose synthase MetaCyc: PWY-2661 LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 SUPERFAMILY SSF51445 435 690 2.94E-111 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS26870 3686448709e1a0c25a4bc327354e24ba 784 SUPERFAMILY SSF51445 1 403 2.94E-111 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS17640 80c43946a7d2b0dd212ecb77be2163b8 120 Pfam PF02635 DsrE/DsrF-like family 3 108 1.5E-10 T 06-07-2017 IPR003787 Sulphur relay, DsrE/F-like protein LK06_RS17640 80c43946a7d2b0dd212ecb77be2163b8 120 Gene3D G3DSA:3.40.1260.10 3 111 2.2E-16 T 06-07-2017 IPR027396 DsrEFH-like LK06_RS17640 80c43946a7d2b0dd212ecb77be2163b8 120 SUPERFAMILY SSF75169 3 112 7.4E-18 T 06-07-2017 IPR027396 DsrEFH-like LK06_RS08830 06a5780118b388b73ef58fc46a4e8156 157 Gene3D G3DSA:3.40.630.30 4 148 8.1E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS08830 06a5780118b388b73ef58fc46a4e8156 157 SUPERFAMILY SSF55729 1 147 4.97E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS08830 06a5780118b388b73ef58fc46a4e8156 157 Pfam PF00583 Acetyltransferase (GNAT) family 74 145 1.2E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS28305 322438bffc656ec3787133847cb0638c 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 130 1.1E-21 T 06-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 LK06_RS28305 322438bffc656ec3787133847cb0638c 132 Gene3D G3DSA:3.30.479.10 2 130 4.7E-42 T 06-07-2017 LK06_RS28305 322438bffc656ec3787133847cb0638c 132 SUPERFAMILY SSF55620 2 129 5.56E-28 T 06-07-2017 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 1.1E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 1.1E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 1.1E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 1.1E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 1.1E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.1E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 1.1E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 1.1E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.1E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 SUPERFAMILY SSF51905 5 305 1.3E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 4.7E-38 T 06-07-2017 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.7E-38 T 06-07-2017 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 4.7E-38 T 06-07-2017 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 4.7E-38 T 06-07-2017 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 4.7E-38 T 06-07-2017 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 306 1.4E-121 T 06-07-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 06-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 295 1.6E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 Gene3D G3DSA:3.50.50.60 105 129 4.5E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 Gene3D G3DSA:3.50.50.60 270 307 4.5E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 Gene3D G3DSA:3.50.50.60 5 104 3.2E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS15915 ba7aa15234e8a4fede54a95bffd55d78 323 Gene3D G3DSA:3.50.50.60 130 240 3.1E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09430 64ba55823665a8f5617e6d2ba6cb5f8c 339 Gene3D G3DSA:3.40.50.10740 1 164 4.7E-36 T 06-07-2017 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain LK06_RS09430 64ba55823665a8f5617e6d2ba6cb5f8c 339 Gene3D G3DSA:3.50.30.60 206 323 3.5E-21 T 06-07-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain LK06_RS09430 64ba55823665a8f5617e6d2ba6cb5f8c 339 SUPERFAMILY SSF52317 2 160 1.42E-36 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS09430 64ba55823665a8f5617e6d2ba6cb5f8c 339 Pfam PF02016 LD-carboxypeptidase 15 323 3.4E-67 T 06-07-2017 IPR003507 Peptidase family S66 LK06_RS09430 64ba55823665a8f5617e6d2ba6cb5f8c 339 SUPERFAMILY SSF141986 204 322 6.02E-22 T 06-07-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain LK06_RS09430 64ba55823665a8f5617e6d2ba6cb5f8c 339 PIRSF PIRSF028757 3 338 1.3E-50 T 06-07-2017 IPR003507 Peptidase family S66 LK06_RS25825 2c507bd7156ff5dcabeffc52546126ce 226 Gene3D G3DSA:1.20.144.10 58 212 4.0E-19 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS25825 2c507bd7156ff5dcabeffc52546126ce 226 Pfam PF01569 PAP2 superfamily 116 208 8.4E-14 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS25825 2c507bd7156ff5dcabeffc52546126ce 226 SMART SM00014 69 203 7.9E-5 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS25825 2c507bd7156ff5dcabeffc52546126ce 226 SUPERFAMILY SSF48317 15 212 1.3E-26 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS21375 6b0a0ad36cb899afb0b982f8750da2a8 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 72 5.8E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS21375 6b0a0ad36cb899afb0b982f8750da2a8 317 SUPERFAMILY SSF53850 100 310 1.03E-38 T 06-07-2017 LK06_RS21375 6b0a0ad36cb899afb0b982f8750da2a8 317 Gene3D G3DSA:3.40.190.10 100 185 5.7E-19 T 06-07-2017 LK06_RS21375 6b0a0ad36cb899afb0b982f8750da2a8 317 SUPERFAMILY SSF46785 4 120 2.33E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21375 6b0a0ad36cb899afb0b982f8750da2a8 317 Gene3D G3DSA:3.40.190.10 186 279 4.9E-24 T 06-07-2017 LK06_RS21375 6b0a0ad36cb899afb0b982f8750da2a8 317 Gene3D G3DSA:1.10.10.10 12 95 8.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21375 6b0a0ad36cb899afb0b982f8750da2a8 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 9.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS21375 6b0a0ad36cb899afb0b982f8750da2a8 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 9.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS21375 6b0a0ad36cb899afb0b982f8750da2a8 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 9.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS21375 6b0a0ad36cb899afb0b982f8750da2a8 317 Pfam PF03466 LysR substrate binding domain 98 305 9.5E-43 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS18205 aabcf6516757c452406d5256a3352d1d 314 Gene3D G3DSA:3.40.630.30 34 156 2.4E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS18205 aabcf6516757c452406d5256a3352d1d 314 PRINTS PR00502 NUDIX hydrolase family signature 216 231 1.2E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS18205 aabcf6516757c452406d5256a3352d1d 314 PRINTS PR00502 NUDIX hydrolase family signature 202 216 1.2E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS18205 aabcf6516757c452406d5256a3352d1d 314 Gene3D G3DSA:3.90.79.10 172 313 2.9E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS18205 aabcf6516757c452406d5256a3352d1d 314 SUPERFAMILY SSF55811 170 312 1.76E-22 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS18205 aabcf6516757c452406d5256a3352d1d 314 Pfam PF00293 NUDIX domain 173 297 4.8E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS18205 aabcf6516757c452406d5256a3352d1d 314 ProSitePatterns PS00893 Nudix box signature. 207 228 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS18205 aabcf6516757c452406d5256a3352d1d 314 SUPERFAMILY SSF55729 20 168 3.4E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS12515 c5aa9391727b5d814fbe373ba0faa169 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.823 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12515 c5aa9391727b5d814fbe373ba0faa169 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 06-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12515 c5aa9391727b5d814fbe373ba0faa169 54 Pfam PF00471 Ribosomal protein L33 9 54 2.6E-23 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12515 c5aa9391727b5d814fbe373ba0faa169 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 2.6E-22 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12515 c5aa9391727b5d814fbe373ba0faa169 54 SUPERFAMILY SSF57829 4 54 3.66E-20 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 LK06_RS30965 6bd2dc41d21afc08c0a2a49862cea5fc 454 SUPERFAMILY SSF56112 156 435 5.44E-22 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS30965 6bd2dc41d21afc08c0a2a49862cea5fc 454 Gene3D G3DSA:3.90.1200.10 252 416 3.0E-8 T 06-07-2017 LK06_RS13830 6670e8d2dbf5d5e048079261abd384af 551 Pfam PF06738 Putative threonine/serine exporter 134 377 1.8E-61 T 06-07-2017 IPR010619 Putative threonine/serine exporter LK06_RS13830 6670e8d2dbf5d5e048079261abd384af 551 Pfam PF12821 Threonine/Serine exporter, ThrE 401 526 3.3E-17 T 06-07-2017 IPR024528 Threonine/Serine exporter, ThrE LK06_RS05025 e91dd2583f9a6329f2a92c30ee406f84 72 Pfam PF05639 Pup-like protein 4 72 7.2E-30 T 06-07-2017 IPR008515 Ubiquitin-like, Pup LK06_RS05025 e91dd2583f9a6329f2a92c30ee406f84 72 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 72 17.412 T 06-07-2017 IPR008515 Ubiquitin-like, Pup LK06_RS05025 e91dd2583f9a6329f2a92c30ee406f84 72 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 41 72 4.6E-21 T 06-07-2017 IPR008515 Ubiquitin-like, Pup LK06_RS25205 19da76d794320752f33f4436ea875c59 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 398 421 7.3E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 436 458 7.3E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 233 252 7.3E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 360 371 7.3E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 464 487 7.3E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 543 570 7.3E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 SUPERFAMILY SSF51998 630 709 3.36E-133 T 06-07-2017 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 SUPERFAMILY SSF51998 158 595 3.36E-133 T 06-07-2017 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 Pfam PF02867 Ribonucleotide reductase, barrel domain 158 697 3.6E-150 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 54 137 5.6E-20 T 06-07-2017 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 92 707 1.8E-190 T 06-07-2017 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 Gene3D G3DSA:3.20.70.20 656 701 1.6E-101 T 06-07-2017 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 Gene3D G3DSA:3.20.70.20 543 589 1.6E-101 T 06-07-2017 LK06_RS25205 19da76d794320752f33f4436ea875c59 964 Gene3D G3DSA:3.20.70.20 68 484 1.6E-101 T 06-07-2017 LK06_RS26355 5b41c862409ff7a82db70c2daf214fe4 207 Pfam PF00857 Isochorismatase family 33 203 3.1E-37 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS26355 5b41c862409ff7a82db70c2daf214fe4 207 SUPERFAMILY SSF52499 3 207 1.03E-62 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS26355 5b41c862409ff7a82db70c2daf214fe4 207 Gene3D G3DSA:3.40.50.850 4 207 8.7E-61 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 LK06_RS26355 5b41c862409ff7a82db70c2daf214fe4 207 PRINTS PR01398 Isochorismatase signature 111 133 3.1E-50 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 LK06_RS26355 5b41c862409ff7a82db70c2daf214fe4 207 PRINTS PR01398 Isochorismatase signature 167 185 3.1E-50 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 LK06_RS26355 5b41c862409ff7a82db70c2daf214fe4 207 PRINTS PR01398 Isochorismatase signature 62 79 3.1E-50 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 LK06_RS26355 5b41c862409ff7a82db70c2daf214fe4 207 PRINTS PR01398 Isochorismatase signature 185 202 3.1E-50 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 LK06_RS26355 5b41c862409ff7a82db70c2daf214fe4 207 PRINTS PR01398 Isochorismatase signature 79 98 3.1E-50 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 LK06_RS26355 5b41c862409ff7a82db70c2daf214fe4 207 PRINTS PR01398 Isochorismatase signature 3 15 3.1E-50 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 LK06_RS26355 5b41c862409ff7a82db70c2daf214fe4 207 PIRSF PIRSF001111 2 207 4.4E-93 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 LK06_RS27200 5630390fceeee4c3a02796e731445da0 221 SUPERFAMILY SSF52833 25 181 1.87E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS27200 5630390fceeee4c3a02796e731445da0 221 Gene3D G3DSA:3.40.30.10 23 179 3.4E-12 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS27200 5630390fceeee4c3a02796e731445da0 221 Pfam PF01323 DSBA-like thioredoxin domain 25 179 9.5E-9 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 LK06_RS19820 b46286388230a824f431e39e512a311b 200 Gene3D G3DSA:3.40.50.1470 8 199 1.8E-70 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 LK06_RS19820 b46286388230a824f431e39e512a311b 200 Pfam PF01195 Peptidyl-tRNA hydrolase 12 197 8.7E-54 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 LK06_RS19820 b46286388230a824f431e39e512a311b 200 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 122 132 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 LK06_RS19820 b46286388230a824f431e39e512a311b 200 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 23 36 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 LK06_RS19820 b46286388230a824f431e39e512a311b 200 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 12 200 8.4E-55 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 LK06_RS19820 b46286388230a824f431e39e512a311b 200 SUPERFAMILY SSF53178 10 199 4.32E-64 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 LK06_RS19820 b46286388230a824f431e39e512a311b 200 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 10 192 33.346 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 Gene3D G3DSA:1.20.1250.20 3 182 1.2E-33 T 06-07-2017 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 Gene3D G3DSA:1.20.1250.20 253 409 1.5E-19 T 06-07-2017 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 Gene3D G3DSA:1.20.1250.20 455 482 1.5E-19 T 06-07-2017 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 5 29 3.1E-12 T 06-07-2017 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 190 208 3.1E-12 T 06-07-2017 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 95 115 3.1E-12 T 06-07-2017 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 389 408 3.1E-12 T 06-07-2017 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 125 149 3.1E-12 T 06-07-2017 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 Pfam PF07690 Major Facilitator Superfamily 6 398 2.0E-47 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 2 476 1.2E-83 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS13630 64fc9fa927986482d932891ec3428274 505 SUPERFAMILY SSF103473 236 408 7.98E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS13630 64fc9fa927986482d932891ec3428274 505 SUPERFAMILY SSF103473 2 181 7.98E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS13630 64fc9fa927986482d932891ec3428274 505 SUPERFAMILY SSF103473 454 478 7.98E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS21865 aa5573f9e15677722584b77c2f9ca4f5 345 Pfam PF00005 ABC transporter 30 187 2.8E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS21865 aa5573f9e15677722584b77c2f9ca4f5 345 SMART SM00382 38 237 8.2E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS21865 aa5573f9e15677722584b77c2f9ca4f5 345 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 301 3.2E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21865 aa5573f9e15677722584b77c2f9ca4f5 345 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 327 2.3E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21865 aa5573f9e15677722584b77c2f9ca4f5 345 Gene3D G3DSA:3.40.50.300 8 260 2.0E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21865 aa5573f9e15677722584b77c2f9ca4f5 345 SUPERFAMILY SSF52540 10 258 2.61E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21865 aa5573f9e15677722584b77c2f9ca4f5 345 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 Pfam PF00575 S1 RNA binding domain 661 731 1.7E-18 T 06-07-2017 IPR003029 S1 domain GO:0003676 LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 SUPERFAMILY SSF50249 649 735 1.79E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 SUPERFAMILY SSF47781 481 569 6.67E-27 T 06-07-2017 IPR010994 RuvA domain 2-like LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 SUPERFAMILY SSF53098 332 480 1.74E-49 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 Gene3D G3DSA:2.40.50.140 649 731 5.0E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 Gene3D G3DSA:1.10.150.310 510 641 1.9E-43 T 06-07-2017 IPR023097 Tex RuvX-like domain LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 Pfam PF12836 Helix-hairpin-helix motif 502 566 1.2E-27 T 06-07-2017 LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 SMART SM00732 336 435 2.0E-37 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 SMART SM00316 660 731 2.7E-24 T 06-07-2017 IPR022967 RNA-binding domain, S1 LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 Gene3D G3DSA:1.10.10.650 11 116 1.8E-43 T 06-07-2017 IPR023319 Tex-like protein, HTH domain LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 SUPERFAMILY SSF47781 571 642 3.33E-19 T 06-07-2017 IPR010994 RuvA domain 2-like LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 SUPERFAMILY SSF158832 11 331 1.31E-111 T 06-07-2017 LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 Pfam PF16921 Tex protein YqgF-like domain 337 462 2.1E-50 T 06-07-2017 IPR032639 Tex protein, YqgF-like domain LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 Gene3D G3DSA:3.30.420.140 336 461 5.5E-50 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 Gene3D G3DSA:1.10.3500.10 462 509 1.8E-99 T 06-07-2017 IPR023323 Tex-like domain LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 Gene3D G3DSA:1.10.3500.10 117 332 1.8E-99 T 06-07-2017 IPR023323 Tex-like domain LK06_RS28660 066903a6c61fa048f849f24785eeb1b1 803 Pfam PF09371 Tex-like protein N-terminal domain 16 200 7.0E-66 T 06-07-2017 IPR018974 Tex-like protein, N-terminal LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 PIRSF PIRSF036421 1 1044 0.0 T 06-07-2017 IPR012393 Tricorn protease GO:0008236 LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 Gene3D G3DSA:2.30.42.10 736 832 3.9E-25 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 SUPERFAMILY SSF50156 737 824 1.8E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 Gene3D G3DSA:3.30.750.44 656 726 3.0E-32 T 06-07-2017 LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 Gene3D G3DSA:2.130.10.10 329 642 1.5E-72 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 Gene3D G3DSA:3.90.226.10 836 1042 1.8E-39 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 Gene3D G3DSA:2.120.10.60 1 257 4.5E-51 T 06-07-2017 LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 SUPERFAMILY SSF69304 3 254 7.72E-31 T 06-07-2017 LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 SUPERFAMILY SSF69304 329 481 9.42E-20 T 06-07-2017 LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 SUPERFAMILY SSF69304 526 633 9.42E-20 T 06-07-2017 LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 Pfam PF14684 Tricorn protease C1 domain 659 726 7.0E-29 T 06-07-2017 IPR028204 Tricorn protease C1 domain LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 Pfam PF03572 Peptidase family S41 856 1010 6.5E-23 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 Pfam PF14685 Tricorn protease PDZ domain 737 826 2.8E-27 T 06-07-2017 IPR029414 Tricorn protease, PDZ domain LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 Pfam PF07676 WD40-like Beta Propeller Repeat 31 52 0.0057 T 06-07-2017 IPR011659 WD40-like Beta Propeller LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 Pfam PF07676 WD40-like Beta Propeller Repeat 455 477 0.02 T 06-07-2017 IPR011659 WD40-like Beta Propeller LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 SUPERFAMILY SSF52096 656 735 6.79E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 SUPERFAMILY SSF52096 828 1037 6.79E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS09475 9ffc7b67c5b07c4fb7e3d3343df7b706 1067 SMART SM00245 806 1011 2.8E-17 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LK06_RS29270 3875c4147192366cf739b9683af0fcc4 168 SUPERFAMILY SSF50370 31 118 2.38E-6 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS29270 3875c4147192366cf739b9683af0fcc4 168 Gene3D G3DSA:2.80.10.50 40 117 9.3E-5 T 06-07-2017 LK06_RS12220 02ebe862f175a22913369ce1a46ec758 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.364 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 LK06_RS12220 02ebe862f175a22913369ce1a46ec758 60 Gene3D G3DSA:3.30.1390.20 1 59 8.3E-28 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain LK06_RS12220 02ebe862f175a22913369ce1a46ec758 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 3.2E-27 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 LK06_RS12220 02ebe862f175a22913369ce1a46ec758 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 06-07-2017 IPR018038 Ribosomal protein L30, conserved site LK06_RS12220 02ebe862f175a22913369ce1a46ec758 60 SUPERFAMILY SSF55129 1 60 6.02E-21 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain LK06_RS12220 02ebe862f175a22913369ce1a46ec758 60 PIRSF PIRSF002211 1 60 2.3E-28 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 LK06_RS12220 02ebe862f175a22913369ce1a46ec758 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 4.8E-17 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain LK06_RS15655 4513c464bd399b9d3d401b6e1d075389 179 SUPERFAMILY SSF103473 7 179 2.35E-32 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS15655 4513c464bd399b9d3d401b6e1d075389 179 Pfam PF07690 Major Facilitator Superfamily 12 173 2.9E-28 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS15655 4513c464bd399b9d3d401b6e1d075389 179 Gene3D G3DSA:1.20.1250.20 8 178 2.6E-25 T 06-07-2017 LK06_RS27615 017a85852e3e08e413b3e2ee4f086fc0 623 Pfam PF00326 Prolyl oligopeptidase family 404 605 2.5E-34 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 LK06_RS27615 017a85852e3e08e413b3e2ee4f086fc0 623 Gene3D G3DSA:3.40.50.1820 290 605 4.0E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27615 017a85852e3e08e413b3e2ee4f086fc0 623 SUPERFAMILY SSF82171 38 332 3.81E-12 T 06-07-2017 LK06_RS27615 017a85852e3e08e413b3e2ee4f086fc0 623 Gene3D G3DSA:2.130.10.10 38 104 7.9E-8 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS27615 017a85852e3e08e413b3e2ee4f086fc0 623 Gene3D G3DSA:2.130.10.10 253 289 7.9E-8 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS27615 017a85852e3e08e413b3e2ee4f086fc0 623 Gene3D G3DSA:2.130.10.10 150 201 7.9E-8 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS27615 017a85852e3e08e413b3e2ee4f086fc0 623 SUPERFAMILY SSF53474 366 605 8.82E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS13010 19d679db2c5b1b3d0a77dac9e56c394c 282 Hamap MF_00995 Chorismate dehydratase [mqnA]. 9 271 30.972 T 06-07-2017 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 LK06_RS13010 19d679db2c5b1b3d0a77dac9e56c394c 282 SUPERFAMILY SSF53850 8 264 5.25E-73 T 06-07-2017 LK06_RS13010 19d679db2c5b1b3d0a77dac9e56c394c 282 Gene3D G3DSA:3.40.190.10 82 183 1.0E-36 T 06-07-2017 LK06_RS13010 19d679db2c5b1b3d0a77dac9e56c394c 282 Gene3D G3DSA:3.40.190.10 184 281 1.8E-66 T 06-07-2017 LK06_RS13010 19d679db2c5b1b3d0a77dac9e56c394c 282 Gene3D G3DSA:3.40.190.10 3 81 1.8E-66 T 06-07-2017 LK06_RS13010 19d679db2c5b1b3d0a77dac9e56c394c 282 Pfam PF02621 Menaquinone biosynthesis 9 265 1.0E-69 T 06-07-2017 IPR003773 Menaquinone biosynthesis enzyme LK06_RS04030 3f87bd5df2f27dd31328a65d1a47f95a 246 SUPERFAMILY SSF64288 55 233 4.71E-42 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS04030 3f87bd5df2f27dd31328a65d1a47f95a 246 Gene3D G3DSA:1.10.10.10 3 72 1.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04030 3f87bd5df2f27dd31328a65d1a47f95a 246 SMART SM00345 8 67 4.1E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS04030 3f87bd5df2f27dd31328a65d1a47f95a 246 Gene3D G3DSA:3.40.1410.10 76 232 4.6E-41 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS04030 3f87bd5df2f27dd31328a65d1a47f95a 246 SUPERFAMILY SSF46785 4 71 1.31E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04030 3f87bd5df2f27dd31328a65d1a47f95a 246 Pfam PF07702 UTRA domain 89 227 2.0E-32 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS04030 3f87bd5df2f27dd31328a65d1a47f95a 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 2.6E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS04030 3f87bd5df2f27dd31328a65d1a47f95a 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 2.6E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS04030 3f87bd5df2f27dd31328a65d1a47f95a 246 SMART SM00866 88 228 8.9E-33 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS04030 3f87bd5df2f27dd31328a65d1a47f95a 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 64 5.0E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS08985 ebf3423d57a99165653357a693a23dec 540 SUPERFAMILY SSF88659 149 203 1.78E-5 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS08985 ebf3423d57a99165653357a693a23dec 540 SMART SM00458 405 535 0.0022 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS08985 ebf3423d57a99165653357a693a23dec 540 SUPERFAMILY SSF50370 401 509 2.35E-13 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS08985 ebf3423d57a99165653357a693a23dec 540 Gene3D G3DSA:1.10.10.10 149 206 5.8E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS08985 ebf3423d57a99165653357a693a23dec 540 Gene3D G3DSA:2.80.10.50 405 502 4.2E-11 T 06-07-2017 LK06_RS08985 ebf3423d57a99165653357a693a23dec 540 Pfam PF00652 Ricin-type beta-trefoil lectin domain 407 482 1.3E-9 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS27045 949816875bc64df0e2f097a5438e628b 197 Gene3D G3DSA:1.10.10.60 1 49 7.8E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS27045 949816875bc64df0e2f097a5438e628b 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 46 3.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS27045 949816875bc64df0e2f097a5438e628b 197 Gene3D G3DSA:1.10.357.10 50 183 5.2E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS27045 949816875bc64df0e2f097a5438e628b 197 SUPERFAMILY SSF46689 7 69 2.77E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS27045 949816875bc64df0e2f097a5438e628b 197 SUPERFAMILY SSF48498 78 182 2.37E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS12510 191839e62662521d27028dd180cc9eea 150 SUPERFAMILY SSF54637 7 147 3.81E-38 T 06-07-2017 IPR029069 HotDog domain LK06_RS12510 191839e62662521d27028dd180cc9eea 150 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 1.3E-36 T 06-07-2017 LK06_RS12510 191839e62662521d27028dd180cc9eea 150 PIRSF PIRSF018072 1 150 2.6E-59 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 LK06_RS12510 191839e62662521d27028dd180cc9eea 150 Gene3D G3DSA:3.10.129.10 1 148 1.1E-38 T 06-07-2017 IPR029069 HotDog domain LK06_RS12510 191839e62662521d27028dd180cc9eea 150 Hamap MF_00799 UPF0336 protein . 1 148 36.265 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 LK06_RS09010 b918ada54004902136126b9fdcc2c30c 383 Pfam PF06032 Protein of unknown function (DUF917) 46 374 9.4E-73 T 06-07-2017 IPR010318 Protein of unknown function DUF917 LK06_RS09010 b918ada54004902136126b9fdcc2c30c 383 SUPERFAMILY SSF160991 41 377 2.88E-68 T 06-07-2017 LK06_RS09010 b918ada54004902136126b9fdcc2c30c 383 Gene3D G3DSA:3.40.1610.10 40 251 2.2E-45 T 06-07-2017 IPR027479 Protein of unknown function DUF917, N-terminal LK06_RS09010 b918ada54004902136126b9fdcc2c30c 383 Gene3D G3DSA:2.40.390.10 259 371 2.1E-12 T 06-07-2017 IPR024071 Protein of unknown function DUF917, C-terminal LK06_RS17495 d87365d31feb27ef4854ee63592c7ef8 402 PIRSF PIRSF002756 34 402 1.6E-123 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 LK06_RS17495 d87365d31feb27ef4854ee63592c7ef8 402 Pfam PF12849 PBP superfamily domain 74 372 1.8E-60 T 06-07-2017 IPR024370 PBP domain LK06_RS17495 d87365d31feb27ef4854ee63592c7ef8 402 Gene3D G3DSA:3.40.190.10 262 399 7.9E-18 T 06-07-2017 LK06_RS17495 d87365d31feb27ef4854ee63592c7ef8 402 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 86 401 7.9E-88 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 LK06_RS17495 d87365d31feb27ef4854ee63592c7ef8 402 SUPERFAMILY SSF53850 84 402 2.6E-88 T 06-07-2017 LK06_RS17495 d87365d31feb27ef4854ee63592c7ef8 402 Gene3D G3DSA:3.40.190.10 82 231 2.2E-46 T 06-07-2017 LK06_RS00440 817810fe581eef6ac322936c528c46c0 293 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 124 5.3E-22 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 LK06_RS00440 817810fe581eef6ac322936c528c46c0 293 SUPERFAMILY SSF111331 1 292 7.85E-63 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain LK06_RS00440 817810fe581eef6ac322936c528c46c0 293 SMART SM00046 3 133 0.0018 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 LK06_RS06500 39e6805031bbf759a261a788bcf067bd 257 PIRSF PIRSF006648 2 257 2.0E-32 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS06500 39e6805031bbf759a261a788bcf067bd 257 Pfam PF01061 ABC-2 type transporter 32 224 2.8E-21 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS00640 6f1ba08ef4d862f38b0d126eb6ed3983 879 Gene3D G3DSA:2.130.10.10 421 546 7.8E-43 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS00640 6f1ba08ef4d862f38b0d126eb6ed3983 879 Gene3D G3DSA:2.130.10.10 291 356 7.8E-43 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS00640 6f1ba08ef4d862f38b0d126eb6ed3983 879 Gene3D G3DSA:2.130.10.10 748 855 7.8E-43 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS00640 6f1ba08ef4d862f38b0d126eb6ed3983 879 Gene3D G3DSA:2.130.10.10 141 231 7.8E-43 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS00640 6f1ba08ef4d862f38b0d126eb6ed3983 879 SUPERFAMILY SSF110296 430 525 2.62E-17 T 06-07-2017 LK06_RS00640 6f1ba08ef4d862f38b0d126eb6ed3983 879 SUPERFAMILY SSF110296 664 841 2.62E-17 T 06-07-2017 LK06_RS00640 6f1ba08ef4d862f38b0d126eb6ed3983 879 SUPERFAMILY SSF50939 424 549 3.92E-6 T 06-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 LK06_RS00640 6f1ba08ef4d862f38b0d126eb6ed3983 879 SUPERFAMILY SSF50939 251 354 3.92E-6 T 06-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 LK06_RS00640 6f1ba08ef4d862f38b0d126eb6ed3983 879 SUPERFAMILY SSF50939 144 209 3.92E-6 T 06-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 LK06_RS10355 0114cd36e786f3075104fdceadfc43c6 541 PRINTS PR01806 Virulence factor MviN signature 434 451 2.6E-20 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS10355 0114cd36e786f3075104fdceadfc43c6 541 PRINTS PR01806 Virulence factor MviN signature 74 90 2.6E-20 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS10355 0114cd36e786f3075104fdceadfc43c6 541 PRINTS PR01806 Virulence factor MviN signature 381 400 2.6E-20 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS10355 0114cd36e786f3075104fdceadfc43c6 541 PRINTS PR01806 Virulence factor MviN signature 55 74 2.6E-20 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS10355 0114cd36e786f3075104fdceadfc43c6 541 PRINTS PR01806 Virulence factor MviN signature 155 179 2.6E-20 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS10355 0114cd36e786f3075104fdceadfc43c6 541 PRINTS PR01806 Virulence factor MviN signature 284 310 2.6E-20 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS10355 0114cd36e786f3075104fdceadfc43c6 541 PRINTS PR01806 Virulence factor MviN signature 179 200 2.6E-20 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS10355 0114cd36e786f3075104fdceadfc43c6 541 Pfam PF03023 MviN-like protein 50 488 6.5E-58 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS01370 7ef20b47c9d06479a73dfaff9c218c3c 90 Pfam PF02627 Carboxymuconolactone decarboxylase family 3 82 1.8E-21 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS01370 7ef20b47c9d06479a73dfaff9c218c3c 90 Gene3D G3DSA:1.20.1290.10 2 85 3.9E-23 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS01370 7ef20b47c9d06479a73dfaff9c218c3c 90 SUPERFAMILY SSF69118 2 84 7.33E-27 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS30390 a0fb960a17c59d66ca8d8888ddd9e401 247 SUPERFAMILY SSF46785 12 76 3.33E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30390 a0fb960a17c59d66ca8d8888ddd9e401 247 SMART SM00345 21 79 5.7E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS30390 a0fb960a17c59d66ca8d8888ddd9e401 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.1E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS30390 a0fb960a17c59d66ca8d8888ddd9e401 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.1E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS30390 a0fb960a17c59d66ca8d8888ddd9e401 247 Gene3D G3DSA:1.10.10.10 14 75 2.8E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30390 a0fb960a17c59d66ca8d8888ddd9e401 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 76 1.1E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS28710 43636666124a2e8736f2fa06919f5cc3 309 Pfam PF01061 ABC-2 type transporter 61 267 1.3E-15 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS28710 43636666124a2e8736f2fa06919f5cc3 309 PRINTS PR00164 ABC-2 type transport system membrane protein signature 221 240 1.1E-5 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS28710 43636666124a2e8736f2fa06919f5cc3 309 PRINTS PR00164 ABC-2 type transport system membrane protein signature 184 208 1.1E-5 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS28710 43636666124a2e8736f2fa06919f5cc3 309 PRINTS PR00164 ABC-2 type transport system membrane protein signature 75 96 1.1E-5 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS16370 6581e89bc8496314f97e5d1037a45a24 243 SUPERFAMILY SSF64288 55 231 5.97E-21 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS16370 6581e89bc8496314f97e5d1037a45a24 243 SMART SM00345 8 67 2.1E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS16370 6581e89bc8496314f97e5d1037a45a24 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.5E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS16370 6581e89bc8496314f97e5d1037a45a24 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.5E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS16370 6581e89bc8496314f97e5d1037a45a24 243 SUPERFAMILY SSF46785 4 70 2.29E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16370 6581e89bc8496314f97e5d1037a45a24 243 Gene3D G3DSA:3.40.1410.10 69 227 1.1E-15 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS16370 6581e89bc8496314f97e5d1037a45a24 243 Gene3D G3DSA:1.10.10.10 4 68 1.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16370 6581e89bc8496314f97e5d1037a45a24 243 Pfam PF07702 UTRA domain 100 226 1.1E-19 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS16370 6581e89bc8496314f97e5d1037a45a24 243 SMART SM00866 88 227 4.3E-8 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS16370 6581e89bc8496314f97e5d1037a45a24 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 67 2.1E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS21750 881bd489cdf20788cba4b9687e8895b0 250 SMART SM00345 12 71 2.7E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS21750 881bd489cdf20788cba4b9687e8895b0 250 Pfam PF07702 UTRA domain 110 242 7.2E-15 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS21750 881bd489cdf20788cba4b9687e8895b0 250 SUPERFAMILY SSF46785 5 82 3.74E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21750 881bd489cdf20788cba4b9687e8895b0 250 Gene3D G3DSA:3.40.1410.10 74 245 1.8E-55 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS21750 881bd489cdf20788cba4b9687e8895b0 250 Gene3D G3DSA:1.10.10.10 8 73 6.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21750 881bd489cdf20788cba4b9687e8895b0 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.3E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS21750 881bd489cdf20788cba4b9687e8895b0 250 SUPERFAMILY SSF64288 59 248 1.4E-25 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS21750 881bd489cdf20788cba4b9687e8895b0 250 SMART SM00866 98 242 2.4E-15 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS28575 f81b64e8e4eac0b870732bf163a94e2b 258 Pfam PF02274 Amidinotransferase 30 149 8.0E-12 T 06-07-2017 LK06_RS28575 f81b64e8e4eac0b870732bf163a94e2b 258 Gene3D G3DSA:3.75.10.10 4 253 3.3E-68 T 06-07-2017 LK06_RS28575 f81b64e8e4eac0b870732bf163a94e2b 258 SUPERFAMILY SSF55909 3 254 4.36E-56 T 06-07-2017 LK06_RS22050 fe077e290d9fa366e68511a4641cb850 377 Pfam PF01883 Domain of unknown function DUF59 4 76 5.7E-16 T 06-07-2017 IPR002744 Domain of unknown function DUF59 LK06_RS22050 fe077e290d9fa366e68511a4641cb850 377 Hamap MF_02040 Iron-sulfur cluster carrier protein. 102 358 35.029 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein LK06_RS22050 fe077e290d9fa366e68511a4641cb850 377 SUPERFAMILY SSF117916 1 89 2.58E-23 T 06-07-2017 LK06_RS22050 fe077e290d9fa366e68511a4641cb850 377 SUPERFAMILY SSF52540 111 360 4.07E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22050 fe077e290d9fa366e68511a4641cb850 377 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 111 357 6.7E-92 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein LK06_RS22050 fe077e290d9fa366e68511a4641cb850 377 Gene3D G3DSA:3.40.50.300 101 356 1.7E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22050 fe077e290d9fa366e68511a4641cb850 377 ProSitePatterns PS01215 Mrp family signature. 215 231 - T 06-07-2017 IPR000808 Mrp, conserved site GO:0005524 LK06_RS22420 2b1a2a4160436331a6c58e5aad03c12b 336 SUPERFAMILY SSF47240 7 323 5.43E-90 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS22420 2b1a2a4160436331a6c58e5aad03c12b 336 PIRSF PIRSF000355 2 334 5.6E-98 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22420 2b1a2a4160436331a6c58e5aad03c12b 336 Pfam PF00268 Ribonucleotide reductase, small chain 15 299 5.7E-81 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LK06_RS22420 2b1a2a4160436331a6c58e5aad03c12b 336 Gene3D G3DSA:1.10.620.20 15 303 4.7E-98 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 LK06_RS12940 691f2e96f42824ced9bfa957ec9964c3 446 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 40 446 46.409 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12940 691f2e96f42824ced9bfa957ec9964c3 446 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 161 446 3.5E-114 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12940 691f2e96f42824ced9bfa957ec9964c3 446 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 44 446 8.0E-173 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12940 691f2e96f42824ced9bfa957ec9964c3 446 Gene3D G3DSA:1.10.645.10 374 439 2.5E-24 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12940 691f2e96f42824ced9bfa957ec9964c3 446 Gene3D G3DSA:1.10.645.10 273 330 2.5E-24 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12940 691f2e96f42824ced9bfa957ec9964c3 446 Gene3D G3DSA:1.10.645.10 36 271 6.6E-45 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12940 691f2e96f42824ced9bfa957ec9964c3 446 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 81 92 - T 06-07-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12940 691f2e96f42824ced9bfa957ec9964c3 446 SUPERFAMILY SSF56762 54 446 6.67E-121 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS24235 65b9969727ae3bda26607d43d87d95b1 321 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 142 3.3E-21 T 06-07-2017 IPR016188 PurM-like, N-terminal domain LK06_RS24235 65b9969727ae3bda26607d43d87d95b1 321 Gene3D G3DSA:3.90.650.10 151 316 2.2E-51 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS24235 65b9969727ae3bda26607d43d87d95b1 321 Pfam PF02769 AIR synthase related protein, C-terminal domain 156 245 1.8E-5 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS24235 65b9969727ae3bda26607d43d87d95b1 321 PIRSF PIRSF005303 3 316 5.7E-90 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 LK06_RS24235 65b9969727ae3bda26607d43d87d95b1 321 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 9 316 2.2E-85 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 LK06_RS24235 65b9969727ae3bda26607d43d87d95b1 321 SUPERFAMILY SSF56042 148 296 7.15E-33 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain LK06_RS24235 65b9969727ae3bda26607d43d87d95b1 321 SUPERFAMILY SSF55326 5 142 4.36E-34 T 06-07-2017 LK06_RS24235 65b9969727ae3bda26607d43d87d95b1 321 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 313 28.911 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 LK06_RS24235 65b9969727ae3bda26607d43d87d95b1 321 Gene3D G3DSA:3.30.1330.10 4 146 1.5E-44 T 06-07-2017 IPR016188 PurM-like, N-terminal domain LK06_RS21255 f8e5d0f836c1ce1ac01ab6f504be8e27 234 SMART SM00858 41 103 1.1E-5 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 LK06_RS21255 f8e5d0f836c1ce1ac01ab6f504be8e27 234 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 107 212 8.6E-21 T 06-07-2017 IPR031571 Flp pilus assembly protein RcpC/CpaB domain LK06_RS21255 f8e5d0f836c1ce1ac01ab6f504be8e27 234 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 10 219 4.5E-28 T 06-07-2017 IPR017592 Pilus assembly, Flp-type CpaB LK06_RS05365 06a8980ad7a33d330505f327d5813651 462 Pfam PF00171 Aldehyde dehydrogenase family 13 459 1.6E-155 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS05365 06a8980ad7a33d330505f327d5813651 462 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 LK06_RS05365 06a8980ad7a33d330505f327d5813651 462 SUPERFAMILY SSF53720 4 460 1.3E-151 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS05365 06a8980ad7a33d330505f327d5813651 462 Gene3D G3DSA:3.40.605.10 6 257 3.9E-85 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS05365 06a8980ad7a33d330505f327d5813651 462 Gene3D G3DSA:3.40.309.10 258 435 1.3E-56 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS07380 ca860ee3d3125ac7059192f9307aefa6 268 Gene3D G3DSA:3.40.50.300 6 201 8.1E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07380 ca860ee3d3125ac7059192f9307aefa6 268 Pfam PF00005 ABC transporter 11 170 9.1E-9 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS07380 ca860ee3d3125ac7059192f9307aefa6 268 SUPERFAMILY SSF52540 6 91 2.8E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS07380 ca860ee3d3125ac7059192f9307aefa6 268 SUPERFAMILY SSF52540 119 202 2.8E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 SUPERFAMILY SSF53901 536 767 2.63E-28 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 SUPERFAMILY SSF53901 459 508 2.63E-28 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 SMART SM00825 Beta-ketoacyl synthase 6 393 1.8E-14 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 407 635 1.1E-9 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 227 3.9E-29 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 Gene3D G3DSA:3.40.47.10 6 239 6.6E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 Gene3D G3DSA:3.40.47.10 245 390 1.5E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 Gene3D G3DSA:3.40.47.10 654 744 9.6E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 645 743 5.0E-8 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 236 348 1.3E-32 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 SUPERFAMILY SSF53901 127 389 3.08E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 SUPERFAMILY SSF53901 5 97 3.08E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS12845 c3f1a2cecaa64215ce0d6c6209eea0ab 771 Gene3D G3DSA:3.40.47.10 403 650 4.9E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS21485 b2a1f7d4c8996ea00772d4e04e495420 344 SUPERFAMILY SSF56655 18 330 3.34E-113 T 06-07-2017 LK06_RS21485 b2a1f7d4c8996ea00772d4e04e495420 344 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 20 331 2.7E-116 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 LK06_RS21485 b2a1f7d4c8996ea00772d4e04e495420 344 Gene3D G3DSA:3.30.540.10 18 190 1.5E-65 T 06-07-2017 LK06_RS21485 b2a1f7d4c8996ea00772d4e04e495420 344 Gene3D G3DSA:3.30.540.10 191 339 4.0E-45 T 06-07-2017 LK06_RS21485 b2a1f7d4c8996ea00772d4e04e495420 344 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 20 327 2.0E-143 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 LK06_RS21485 b2a1f7d4c8996ea00772d4e04e495420 344 PIRSF PIRSF004532 18 338 2.7E-145 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 LK06_RS26690 56c58a8641b387118e06506844733773 249 SMART SM00244 22 180 4.8E-63 T 06-07-2017 IPR001107 Band 7 domain LK06_RS26690 56c58a8641b387118e06506844733773 249 SUPERFAMILY SSF117892 54 187 1.57E-41 T 06-07-2017 IPR001107 Band 7 domain LK06_RS26690 56c58a8641b387118e06506844733773 249 Pfam PF01145 SPFH domain / Band 7 family 26 196 2.0E-33 T 06-07-2017 IPR001107 Band 7 domain LK06_RS26690 56c58a8641b387118e06506844733773 249 PRINTS PR00721 Stomatin signature 29 51 8.0E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS26690 56c58a8641b387118e06506844733773 249 PRINTS PR00721 Stomatin signature 112 129 8.0E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS26690 56c58a8641b387118e06506844733773 249 PRINTS PR00721 Stomatin signature 175 196 8.0E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS26690 56c58a8641b387118e06506844733773 249 PRINTS PR00721 Stomatin signature 156 174 8.0E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS26690 56c58a8641b387118e06506844733773 249 PRINTS PR00721 Stomatin signature 132 155 8.0E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS26690 56c58a8641b387118e06506844733773 249 PRINTS PR00721 Stomatin signature 77 98 8.0E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS26690 56c58a8641b387118e06506844733773 249 PRINTS PR00721 Stomatin signature 200 223 8.0E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 LK06_RS24315 e64b0f55d7801e0d914866e044b9864f 187 ProSitePatterns PS00079 Multicopper oxidases signature 1. 163 183 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site LK06_RS24315 e64b0f55d7801e0d914866e044b9864f 187 Gene3D G3DSA:2.60.40.420 41 186 9.7E-19 T 06-07-2017 IPR008972 Cupredoxin LK06_RS24315 e64b0f55d7801e0d914866e044b9864f 187 SUPERFAMILY SSF49503 73 186 2.89E-12 T 06-07-2017 IPR008972 Cupredoxin LK06_RS10260 1e7504b69764f4d0c5584bc257638b76 63 Pfam PF01381 Helix-turn-helix 7 61 4.0E-17 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS10260 1e7504b69764f4d0c5584bc257638b76 63 Gene3D G3DSA:1.10.260.40 6 62 1.7E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10260 1e7504b69764f4d0c5584bc257638b76 63 SUPERFAMILY SSF47413 6 62 1.9E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10260 1e7504b69764f4d0c5584bc257638b76 63 SMART SM00530 6 61 3.2E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 197 207 7.8E-21 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 7.8E-21 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 144 165 7.8E-21 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 7.8E-21 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 Pfam PF00579 tRNA synthetases class I (W and Y) 2 283 1.7E-68 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 Gene3D G3DSA:3.40.50.620 2 216 1.9E-78 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 SUPERFAMILY SSF52374 2 328 2.31E-78 T 06-07-2017 LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 Gene3D G3DSA:1.10.240.10 217 317 6.8E-11 T 06-07-2017 LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 328 9.0E-93 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LK06_RS13520 7dc34ac851a85209e3a0e5bd7c8529c0 342 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 329 35.931 T 06-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 LK06_RS20815 dcf08e92862f9ec366c5840705938008 274 SUPERFAMILY SSF53167 17 273 2.36E-79 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS20815 dcf08e92862f9ec366c5840705938008 274 Gene3D G3DSA:3.40.50.1580 14 273 2.6E-89 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS20815 dcf08e92862f9ec366c5840705938008 274 PIRSF PIRSF000477 9 274 1.9E-88 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 LK06_RS20815 dcf08e92862f9ec366c5840705938008 274 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 35 271 6.2E-103 T 06-07-2017 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 LK06_RS20815 dcf08e92862f9ec366c5840705938008 274 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 89 130 - T 06-07-2017 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 LK06_RS20815 dcf08e92862f9ec366c5840705938008 274 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 35 271 1.5E-76 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 LK06_RS20815 dcf08e92862f9ec366c5840705938008 274 Pfam PF01048 Phosphorylase superfamily 36 271 1.5E-40 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 SUPERFAMILY SSF51430 8 268 3.93E-96 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 Gene3D G3DSA:3.20.20.100 9 274 1.2E-106 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 231 246 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 Pfam PF00248 Aldo/keto reductase family 19 263 1.6E-49 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 PRINTS PR00069 Aldo-keto reductase signature 126 143 1.8E-48 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 PRINTS PR00069 Aldo-keto reductase signature 160 189 1.8E-48 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 PRINTS PR00069 Aldo-keto reductase signature 38 62 1.8E-48 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 PRINTS PR00069 Aldo-keto reductase signature 198 222 1.8E-48 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 PRINTS PR00069 Aldo-keto reductase signature 94 112 1.8E-48 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 LK06_RS28210 cde5ccfa4b77bb5334924cb1090de8ae 278 PIRSF PIRSF000097 2 274 3.0E-89 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 Pfam PF06723 MreB/Mbl protein 11 333 2.5E-107 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 SUPERFAMILY SSF53067 11 149 3.46E-21 T 06-07-2017 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 68 91 2.2E-38 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 48 66 2.2E-38 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 302 328 2.2E-38 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 2.2E-38 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 2.2E-38 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 SUPERFAMILY SSF53067 151 330 3.36E-31 T 06-07-2017 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 Gene3D G3DSA:3.90.640.10 188 261 3.3E-12 T 06-07-2017 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 Gene3D G3DSA:3.30.420.40 265 319 3.6E-21 T 06-07-2017 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 Gene3D G3DSA:3.30.420.40 160 187 3.6E-21 T 06-07-2017 LK06_RS08960 d51c36a27d190d57bdf6b35bf2e965c9 345 Gene3D G3DSA:3.30.420.40 12 159 3.2E-20 T 06-07-2017 LK06_RS12760 2811a38c92615ecb1c3f63ac6ebe9ab6 400 Gene3D G3DSA:3.50.50.60 198 381 4.7E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS12760 2811a38c92615ecb1c3f63ac6ebe9ab6 400 Gene3D G3DSA:3.50.50.60 106 197 5.3E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS12760 2811a38c92615ecb1c3f63ac6ebe9ab6 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 365 1.4E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS12760 2811a38c92615ecb1c3f63ac6ebe9ab6 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 2.4E-6 T 06-07-2017 LK06_RS12760 2811a38c92615ecb1c3f63ac6ebe9ab6 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.4E-6 T 06-07-2017 LK06_RS12760 2811a38c92615ecb1c3f63ac6ebe9ab6 400 Gene3D G3DSA:3.50.50.60 3 45 8.9E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS12760 2811a38c92615ecb1c3f63ac6ebe9ab6 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 182 207 5.2E-9 T 06-07-2017 LK06_RS12760 2811a38c92615ecb1c3f63ac6ebe9ab6 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 381 396 5.2E-9 T 06-07-2017 LK06_RS12760 2811a38c92615ecb1c3f63ac6ebe9ab6 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 5.2E-9 T 06-07-2017 LK06_RS12760 2811a38c92615ecb1c3f63ac6ebe9ab6 400 SUPERFAMILY SSF51905 5 397 9.19E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20290 c35abfc8c5996d12e302dcf072f88291 494 Pfam PF01551 Peptidase family M23 388 482 5.9E-30 T 06-07-2017 IPR016047 Peptidase M23 LK06_RS20290 c35abfc8c5996d12e302dcf072f88291 494 SUPERFAMILY SSF51261 364 486 8.37E-43 T 06-07-2017 IPR011055 Duplicated hybrid motif LK06_RS20290 c35abfc8c5996d12e302dcf072f88291 494 Gene3D G3DSA:2.70.70.10 342 487 1.5E-42 T 06-07-2017 LK06_RS19050 eed6fe881296aabbf848f28f582a5b71 248 Gene3D G3DSA:1.10.3630.10 3 210 3.5E-39 T 06-07-2017 LK06_RS19050 eed6fe881296aabbf848f28f582a5b71 248 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 202 9.4E-46 T 06-07-2017 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 LK06_RS16760 64e94c9bc0732773bc4fcd603e7e7929 496 Gene3D G3DSA:2.40.10.10 4 94 1.2E-6 T 06-07-2017 LK06_RS16760 64e94c9bc0732773bc4fcd603e7e7929 496 SUPERFAMILY SSF69318 214 478 4.19E-14 T 06-07-2017 LK06_RS16760 64e94c9bc0732773bc4fcd603e7e7929 496 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 246 309 1.1E-8 T 06-07-2017 LK06_RS16760 64e94c9bc0732773bc4fcd603e7e7929 496 Pfam PF00089 Trypsin 4 160 2.1E-7 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 LK06_RS16760 64e94c9bc0732773bc4fcd603e7e7929 496 SUPERFAMILY SSF50494 3 182 9.76E-16 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS16760 64e94c9bc0732773bc4fcd603e7e7929 496 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 20 25 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 LK06_RS03025 fb3e7d9e6e4b1c94467d99320b3f0419 345 Gene3D G3DSA:3.40.50.150 99 262 4.7E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03025 fb3e7d9e6e4b1c94467d99320b3f0419 345 Pfam PF13489 Methyltransferase domain 105 259 4.5E-22 T 06-07-2017 LK06_RS03025 fb3e7d9e6e4b1c94467d99320b3f0419 345 SUPERFAMILY SSF53335 76 283 2.39E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS30660 77e20a96c0131c03ea4b08de1c56bf24 259 Pfam PF00561 alpha/beta hydrolase fold 25 243 6.9E-25 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS30660 77e20a96c0131c03ea4b08de1c56bf24 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 2.5E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS30660 77e20a96c0131c03ea4b08de1c56bf24 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 2.5E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS30660 77e20a96c0131c03ea4b08de1c56bf24 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 2.5E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS30660 77e20a96c0131c03ea4b08de1c56bf24 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.5E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS30660 77e20a96c0131c03ea4b08de1c56bf24 259 SUPERFAMILY SSF53474 2 255 2.14E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30660 77e20a96c0131c03ea4b08de1c56bf24 259 Gene3D G3DSA:3.40.50.1820 2 256 6.6E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30370 720f9dc38834718bb6d3f7943e5455a7 393 Gene3D G3DSA:3.40.710.10 67 319 1.2E-65 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS30370 720f9dc38834718bb6d3f7943e5455a7 393 SUPERFAMILY SSF56601 63 319 2.82E-49 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS30370 720f9dc38834718bb6d3f7943e5455a7 393 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 68 298 5.5E-34 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 LK06_RS30370 720f9dc38834718bb6d3f7943e5455a7 393 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 168 5.1E-6 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LK06_RS30370 720f9dc38834718bb6d3f7943e5455a7 393 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 100 111 5.1E-6 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LK06_RS30370 720f9dc38834718bb6d3f7943e5455a7 393 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 177 190 5.1E-6 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LK06_RS02355 6de7599ad34f9986b8e23834a5cca545 286 Gene3D G3DSA:1.10.260.40 7 70 2.4E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS02355 6de7599ad34f9986b8e23834a5cca545 286 SMART SM00530 15 70 2.4E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS02355 6de7599ad34f9986b8e23834a5cca545 286 Pfam PF13560 Helix-turn-helix domain 12 73 2.8E-15 T 06-07-2017 LK06_RS02355 6de7599ad34f9986b8e23834a5cca545 286 SUPERFAMILY SSF47413 8 70 2.95E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS00235 e7b71280bc21b4e291de8de088a59d5f 589 Gene3D G3DSA:3.40.50.300 91 104 4.5E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00235 e7b71280bc21b4e291de8de088a59d5f 589 Gene3D G3DSA:3.40.50.300 182 441 4.5E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00235 e7b71280bc21b4e291de8de088a59d5f 589 SUPERFAMILY SSF47917 455 539 1.49E-7 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS00235 e7b71280bc21b4e291de8de088a59d5f 589 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 24 84 7.7E-4 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS00235 e7b71280bc21b4e291de8de088a59d5f 589 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 102 210 1.6E-16 T 06-07-2017 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 LK06_RS00235 e7b71280bc21b4e291de8de088a59d5f 589 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 219 440 3.9E-79 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS00235 e7b71280bc21b4e291de8de088a59d5f 589 Gene3D G3DSA:1.10.1140.10 456 530 2.9E-5 T 06-07-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 LK06_RS00235 e7b71280bc21b4e291de8de088a59d5f 589 SUPERFAMILY SSF52540 187 444 9.01E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00235 e7b71280bc21b4e291de8de088a59d5f 589 SMART SM00382 231 424 4.3E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS28610 49e56fa6190bebdd5af15350548fb9dd 128 SUPERFAMILY SSF142906 10 121 8.76E-23 T 06-07-2017 LK06_RS28610 49e56fa6190bebdd5af15350548fb9dd 128 Pfam PF04237 YjbR 19 112 5.1E-16 T 06-07-2017 IPR007351 Uncharacterised protein YjbR LK06_RS08850 47962fe855982c53509493b2fc22fa9d 311 SUPERFAMILY SSF55048 127 182 2.35E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 LK06_RS08850 47962fe855982c53509493b2fc22fa9d 311 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 294 9.6E-19 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain LK06_RS08850 47962fe855982c53509493b2fc22fa9d 311 Gene3D G3DSA:3.30.70.250 124 188 8.0E-22 T 06-07-2017 LK06_RS08850 47962fe855982c53509493b2fc22fa9d 311 SUPERFAMILY SSF52151 2 119 3.14E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS08850 47962fe855982c53509493b2fc22fa9d 311 SUPERFAMILY SSF52151 182 305 3.14E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 LK06_RS08850 47962fe855982c53509493b2fc22fa9d 311 Gene3D G3DSA:3.40.366.10 189 296 8.5E-55 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS08850 47962fe855982c53509493b2fc22fa9d 311 Gene3D G3DSA:3.40.366.10 2 119 8.5E-55 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 LK06_RS08850 47962fe855982c53509493b2fc22fa9d 311 Pfam PF00698 Acyl transferase domain 5 281 1.6E-20 T 06-07-2017 IPR014043 Acyl transferase LK06_RS21335 4cfc3048d079ee22309786c732407c3d 257 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 28 257 36.907 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LK06_RS21335 4cfc3048d079ee22309786c732407c3d 257 Gene3D G3DSA:3.40.1180.10 14 257 1.3E-88 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LK06_RS21335 4cfc3048d079ee22309786c732407c3d 257 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 202 219 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 LK06_RS21335 4cfc3048d079ee22309786c732407c3d 257 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 28 256 9.8E-68 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LK06_RS21335 4cfc3048d079ee22309786c732407c3d 257 SUPERFAMILY SSF64005 26 251 1.96E-76 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LK06_RS21335 4cfc3048d079ee22309786c732407c3d 257 Pfam PF01255 Putative undecaprenyl diphosphate synthase 35 256 1.3E-72 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LK06_RS24705 8899869569df4d9dda7d9deb24037e57 433 SUPERFAMILY SSF50156 128 239 2.1E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS24705 8899869569df4d9dda7d9deb24037e57 433 Pfam PF13180 PDZ domain 181 239 1.9E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS24705 8899869569df4d9dda7d9deb24037e57 433 SMART SM00228 149 231 2.5E-5 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS24705 8899869569df4d9dda7d9deb24037e57 433 Pfam PF02163 Peptidase family M50 13 385 1.1E-46 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 LK06_RS24705 8899869569df4d9dda7d9deb24037e57 433 Gene3D G3DSA:2.30.42.10 122 240 3.8E-24 T 06-07-2017 IPR001478 PDZ domain GO:0005515 LK06_RS26345 e566080885d996aaddc5345d07286a41 400 SUPERFAMILY SSF51569 21 398 7.25E-136 T 06-07-2017 LK06_RS26345 e566080885d996aaddc5345d07286a41 400 Pfam PF01474 Class-II DAHP synthetase family 22 175 2.0E-41 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 LK06_RS26345 e566080885d996aaddc5345d07286a41 400 Pfam PF01474 Class-II DAHP synthetase family 183 394 1.4E-78 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 LK06_RS15665 f0d430c3f9bece360249af20390a0abd 137 SUPERFAMILY SSF88723 13 127 9.81E-8 T 06-07-2017 IPR029060 PIN domain-like LK06_RS27250 86a58c33276d9caef61dde375874627e 272 SUPERFAMILY SSF56059 107 251 1.11E-8 T 06-07-2017 LK06_RS12930 858ec38afd7d86d8368bb183df69b189 448 Pfam PF10531 SLBB domain 255 301 2.5E-7 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12930 858ec38afd7d86d8368bb183df69b189 448 SUPERFAMILY SSF142019 19 250 6.28E-86 T 06-07-2017 LK06_RS12930 858ec38afd7d86d8368bb183df69b189 448 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 59 230 2.9E-45 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12930 858ec38afd7d86d8368bb183df69b189 448 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 352 363 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12930 858ec38afd7d86d8368bb183df69b189 448 SUPERFAMILY SSF142984 253 334 2.22E-21 T 06-07-2017 LK06_RS12930 858ec38afd7d86d8368bb183df69b189 448 SMART SM00928 339 384 4.0E-26 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12930 858ec38afd7d86d8368bb183df69b189 448 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 22 425 2.9E-191 T 06-07-2017 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12930 858ec38afd7d86d8368bb183df69b189 448 SUPERFAMILY SSF140490 335 434 3.53E-38 T 06-07-2017 LK06_RS12930 858ec38afd7d86d8368bb183df69b189 448 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 178 193 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12930 858ec38afd7d86d8368bb183df69b189 448 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 341 424 2.1E-32 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS11485 1db8c13881be7a7a329dfaec734c14ca 339 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 168 332 4.2E-12 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS11485 1db8c13881be7a7a329dfaec734c14ca 339 SUPERFAMILY SSF81606 149 333 3.92E-14 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS11485 1db8c13881be7a7a329dfaec734c14ca 339 SMART SM00331 144 334 1.1E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS11485 1db8c13881be7a7a329dfaec734c14ca 339 SUPERFAMILY SSF55874 36 131 2.55E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS29080 c813425c890e8975369b72788eef7e47 114 SUPERFAMILY SSF51182 14 112 2.72E-15 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS29080 c813425c890e8975369b72788eef7e47 114 Pfam PF05899 Protein of unknown function (DUF861) 39 110 3.3E-18 T 06-07-2017 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 LK06_RS29080 c813425c890e8975369b72788eef7e47 114 Gene3D G3DSA:2.60.120.10 16 112 1.1E-26 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS02710 a765c46aa5f47d7f63454bb76cc076a4 429 Gene3D G3DSA:3.40.640.10 74 262 1.3E-45 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS02710 a765c46aa5f47d7f63454bb76cc076a4 429 Gene3D G3DSA:3.90.1150.10 263 426 7.9E-26 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS02710 a765c46aa5f47d7f63454bb76cc076a4 429 Pfam PF00155 Aminotransferase class I and II 74 421 3.5E-26 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS02710 a765c46aa5f47d7f63454bb76cc076a4 429 SUPERFAMILY SSF53383 28 424 1.46E-73 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS20195 d14de8579ed8c436018dcb1f8fc4546f 579 SUPERFAMILY SSF56112 6 262 2.29E-65 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS20195 d14de8579ed8c436018dcb1f8fc4546f 579 Gene3D G3DSA:1.10.510.10 80 261 1.1E-46 T 06-07-2017 LK06_RS20195 d14de8579ed8c436018dcb1f8fc4546f 579 Pfam PF00069 Protein kinase domain 11 258 1.8E-44 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20195 d14de8579ed8c436018dcb1f8fc4546f 579 Gene3D G3DSA:3.30.200.20 5 79 9.7E-22 T 06-07-2017 LK06_RS20195 d14de8579ed8c436018dcb1f8fc4546f 579 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS20195 d14de8579ed8c436018dcb1f8fc4546f 579 SMART SM00220 10 268 3.5E-53 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS20195 d14de8579ed8c436018dcb1f8fc4546f 579 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS01515 7acba6ae222f76e9a318a38073eb073b 640 SUPERFAMILY SSF52540 5 234 5.01E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01515 7acba6ae222f76e9a318a38073eb073b 640 Pfam PF00350 Dynamin family 55 214 1.3E-6 T 06-07-2017 IPR022812 Dynamin superfamily LK06_RS01515 7acba6ae222f76e9a318a38073eb073b 640 Gene3D G3DSA:3.40.50.300 131 229 1.2E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01515 7acba6ae222f76e9a318a38073eb073b 640 Gene3D G3DSA:3.40.50.300 10 48 1.2E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26625 df6b315d2abccf412a3ab7e04d775c89 274 SUPERFAMILY SSF144091 93 254 1.23E-38 T 06-07-2017 LK06_RS26625 df6b315d2abccf412a3ab7e04d775c89 274 SUPERFAMILY SSF144091 11 62 1.23E-38 T 06-07-2017 LK06_RS26625 df6b315d2abccf412a3ab7e04d775c89 274 Gene3D G3DSA:1.20.1540.10 13 53 1.0E-41 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 LK06_RS26625 df6b315d2abccf412a3ab7e04d775c89 274 Gene3D G3DSA:1.20.1540.10 93 251 1.0E-41 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 LK06_RS26625 df6b315d2abccf412a3ab7e04d775c89 274 Pfam PF01694 Rhomboid family 101 249 4.7E-37 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 LK06_RS26485 e6c99fc9b4861f6379eb4ae30bff6997 120 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1 31 9.0E-5 T 06-07-2017 IPR006530 YD repeat LK06_RS26485 e6c99fc9b4861f6379eb4ae30bff6997 120 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 40 66 0.0033 T 06-07-2017 IPR006530 YD repeat LK06_RS26485 e6c99fc9b4861f6379eb4ae30bff6997 120 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 90 119 1.4E-8 T 06-07-2017 IPR006530 YD repeat LK06_RS26485 e6c99fc9b4861f6379eb4ae30bff6997 120 Pfam PF05593 RHS Repeat 90 119 1.4E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS26485 e6c99fc9b4861f6379eb4ae30bff6997 120 Pfam PF05593 RHS Repeat 2 28 3.6E-6 T 06-07-2017 IPR031325 RHS repeat LK06_RS09560 10fbd1e88a7b979105dbdee4109c93e9 411 Pfam PF10531 SLBB domain 268 320 6.8E-9 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS09560 10fbd1e88a7b979105dbdee4109c93e9 411 SUPERFAMILY SSF47781 346 407 4.11E-23 T 06-07-2017 IPR010994 RuvA domain 2-like LK06_RS09560 10fbd1e88a7b979105dbdee4109c93e9 411 Gene3D G3DSA:3.10.560.10 257 312 8.3E-6 T 06-07-2017 LK06_RS09560 10fbd1e88a7b979105dbdee4109c93e9 411 Pfam PF12836 Helix-hairpin-helix motif 350 410 1.5E-19 T 06-07-2017 LK06_RS09560 10fbd1e88a7b979105dbdee4109c93e9 411 Gene3D G3DSA:1.10.150.280 346 409 1.1E-17 T 06-07-2017 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 Gene3D G3DSA:3.40.50.620 2 233 1.8E-89 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 419 43.909 T 06-07-2017 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 419 3.3E-112 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 2.3E-25 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 2.3E-25 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 2.3E-25 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 2.3E-25 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 Gene3D G3DSA:1.10.240.10 234 317 5.4E-41 T 06-07-2017 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 Gene3D G3DSA:3.10.290.10 318 419 2.6E-31 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 SUPERFAMILY SSF52374 3 324 6.91E-94 T 06-07-2017 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 SUPERFAMILY SSF55174 327 418 1.77E-15 T 06-07-2017 LK06_RS06030 f82d07979f9363b019ad1eb7ca33d6fa 422 Pfam PF00579 tRNA synthetases class I (W and Y) 30 324 1.0E-75 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS29715 5d611d60c2ba00ccc2b3aff8f068418e 140 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 9 140 1.3E-19 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 LK06_RS29715 5d611d60c2ba00ccc2b3aff8f068418e 140 PIRSF PIRSF004681 4 140 9.8E-29 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 LK06_RS29715 5d611d60c2ba00ccc2b3aff8f068418e 140 Pfam PF01894 Uncharacterised protein family UPF0047 22 136 1.1E-22 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 LK06_RS29715 5d611d60c2ba00ccc2b3aff8f068418e 140 SUPERFAMILY SSF111038 6 140 5.1E-33 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 LK06_RS29715 5d611d60c2ba00ccc2b3aff8f068418e 140 Gene3D G3DSA:2.60.120.460 5 140 2.1E-32 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 LK06_RS21090 70b067c4f3f3c5435a920644abf4ceb5 328 SUPERFAMILY SSF51197 28 321 1.24E-56 T 06-07-2017 LK06_RS21090 70b067c4f3f3c5435a920644abf4ceb5 328 PIRSF PIRSF019543 7 328 4.7E-95 T 06-07-2017 IPR014503 Clavaminate synthase GO:0005506|GO:0017000|GO:0033758|GO:0055114 LK06_RS21090 70b067c4f3f3c5435a920644abf4ceb5 328 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 75 306 8.7E-14 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 LK06_RS21090 70b067c4f3f3c5435a920644abf4ceb5 328 Gene3D G3DSA:3.60.130.10 30 319 1.7E-57 T 06-07-2017 LK06_RS03720 f6fee865741468700f26b73d021a883a 143 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 16 47 9.4E-8 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal LK06_RS03720 f6fee865741468700f26b73d021a883a 143 SUPERFAMILY SSF50249 5 119 5.14E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS20270 e74fa6b50866e5d60d2625e26ef79255 354 SUPERFAMILY SSF54001 237 353 1.14E-44 T 06-07-2017 LK06_RS20270 e74fa6b50866e5d60d2625e26ef79255 354 Pfam PF00877 NlpC/P60 family 254 345 2.6E-28 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS20270 e74fa6b50866e5d60d2625e26ef79255 354 Gene3D G3DSA:3.90.1720.10 237 353 1.2E-46 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 Pfam PF13404 AsnC-type helix-turn-helix domain 27 67 4.0E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 Gene3D G3DSA:3.30.70.920 90 161 1.5E-17 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 SMART SM00344 27 131 2.8E-36 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 Pfam PF01037 Lrp/AsnC ligand binding domain 92 161 1.6E-15 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 54 2.9E-11 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 54 73 2.9E-11 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 43 2.9E-11 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 SUPERFAMILY SSF46785 26 81 5.52E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 SUPERFAMILY SSF54909 89 168 8.58E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 Gene3D G3DSA:1.10.10.10 25 74 4.7E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS24575 97b7b7414e804615fa098f7b8e7dabe3 172 ProSitePatterns PS00519 AsnC-type HTH domain signature. 45 71 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LK06_RS28105 562669205af63ac8ec7aab2dd31ed606 539 Gene3D G3DSA:3.40.50.300 348 525 2.2E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28105 562669205af63ac8ec7aab2dd31ed606 539 Pfam PF00005 ABC transporter 21 191 8.5E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS28105 562669205af63ac8ec7aab2dd31ed606 539 Pfam PF00005 ABC transporter 350 475 8.2E-13 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS28105 562669205af63ac8ec7aab2dd31ed606 539 SUPERFAMILY SSF52540 348 527 8.33E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28105 562669205af63ac8ec7aab2dd31ed606 539 SUPERFAMILY SSF52540 4 96 8.21E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28105 562669205af63ac8ec7aab2dd31ed606 539 SUPERFAMILY SSF52540 128 235 8.21E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28105 562669205af63ac8ec7aab2dd31ed606 539 Gene3D G3DSA:3.40.50.300 129 235 5.6E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28105 562669205af63ac8ec7aab2dd31ed606 539 Gene3D G3DSA:3.40.50.300 3 90 5.6E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28105 562669205af63ac8ec7aab2dd31ed606 539 SMART SM00382 356 527 7.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS28105 562669205af63ac8ec7aab2dd31ed606 539 SMART SM00382 29 236 7.7E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS06820 cc7fa26b57ce6a6ff6e55c3b3e166966 243 SMART SM00987 49 227 6.5E-31 T 06-07-2017 LK06_RS06820 cc7fa26b57ce6a6ff6e55c3b3e166966 243 SMART SM00986 49 227 6.5E-31 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS06820 cc7fa26b57ce6a6ff6e55c3b3e166966 243 Pfam PF03167 Uracil DNA glycosylase superfamily 49 227 6.1E-28 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS06820 cc7fa26b57ce6a6ff6e55c3b3e166966 243 Gene3D G3DSA:3.40.470.10 7 235 6.4E-54 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS06820 cc7fa26b57ce6a6ff6e55c3b3e166966 243 SUPERFAMILY SSF52141 17 229 6.54E-43 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LK06_RS32220 125d80f07c1aa520c896c21b48f0bca7 442 Pfam PF01580 FtsK/SpoIIIE family 179 358 4.4E-17 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS32220 125d80f07c1aa520c896c21b48f0bca7 442 SUPERFAMILY SSF52540 165 413 5.8E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32220 125d80f07c1aa520c896c21b48f0bca7 442 Gene3D G3DSA:3.40.50.300 171 367 3.0E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29600 70a2353dc5d512e18fc9e60c3198b3ad 436 SUPERFAMILY SSF46894 235 300 6.24E-5 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS29600 70a2353dc5d512e18fc9e60c3198b3ad 436 Gene3D G3DSA:1.10.10.10 236 300 6.2E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29600 70a2353dc5d512e18fc9e60c3198b3ad 436 SMART SM00862 244 310 9.4E-5 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS29600 70a2353dc5d512e18fc9e60c3198b3ad 436 Pfam PF01590 GAF domain 106 214 1.1E-6 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS03890 f158f06a2eb3d785dc98994572965355 453 Pfam PF13529 Peptidase_C39 like family 253 391 1.1E-27 T 06-07-2017 LK06_RS10685 819ce322d66238149f6cf8f8994b8991 547 Pfam PF13556 PucR C-terminal helix-turn-helix domain 488 545 4.5E-20 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS10685 819ce322d66238149f6cf8f8994b8991 547 Pfam PF07905 Purine catabolism regulatory protein-like family 34 169 3.7E-19 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 Gene3D G3DSA:1.20.1250.20 485 509 1.2E-16 T 06-07-2017 LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 Gene3D G3DSA:1.20.1250.20 276 433 1.2E-16 T 06-07-2017 LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 SUPERFAMILY SSF103473 261 432 5.75E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 SUPERFAMILY SSF103473 18 212 5.75E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 SUPERFAMILY SSF103473 484 510 5.75E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 Pfam PF07690 Major Facilitator Superfamily 30 422 4.8E-48 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 6.9E-10 T 06-07-2017 LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 6.9E-10 T 06-07-2017 LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 PRINTS PR01036 Tetracycline resistance protein TetB signature 88 110 6.9E-10 T 06-07-2017 LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 6.9E-10 T 06-07-2017 LK06_RS05595 7ed158ea8e338f19ffd03cf450ef2609 573 Gene3D G3DSA:1.20.1250.20 26 206 2.8E-30 T 06-07-2017 LK06_RS14975 6340f6cff10b86e50324f1666a92eb17 191 SUPERFAMILY SSF55961 46 189 1.75E-10 T 06-07-2017 LK06_RS20325 8b9a6ec9431d8cf38b3973e23de8ee04 391 Gene3D G3DSA:3.40.50.410 219 337 1.2E-4 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS20325 8b9a6ec9431d8cf38b3973e23de8ee04 391 SUPERFAMILY SSF53300 219 379 1.46E-22 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS20325 8b9a6ec9431d8cf38b3973e23de8ee04 391 Pfam PF05762 VWA domain containing CoxE-like protein 156 375 8.9E-61 T 06-07-2017 IPR008912 Uncharacterised protein family CoxE-like LK06_RS15835 728d3c153646f291d60ee40da9df7c83 193 Hamap MF_00630 UPF0232 protein . 5 179 29.817 T 06-07-2017 IPR023007 Uncharacterised protein family UPF0232, actinobacteria LK06_RS15835 728d3c153646f291d60ee40da9df7c83 193 Pfam PF05258 Protein of unknown function (DUF721) 79 167 1.6E-24 T 06-07-2017 IPR007922 Protein of unknown function DUF721/UPF0232 LK06_RS11150 26ca4e7808e9aa2f2b57649056a70b17 257 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 114 171 6.9E-7 T 06-07-2017 IPR024425 Cell wall-active antibiotics response 4TMS YvqF LK06_RS11150 26ca4e7808e9aa2f2b57649056a70b17 257 Pfam PF08044 Domain of unknown function (DUF1707) 9 61 3.2E-24 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 LK06_RS21400 8797e2b657fc3e40a9faae28fa54bb61 229 SMART SM00382 33 221 3.0E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS21400 8797e2b657fc3e40a9faae28fa54bb61 229 Gene3D G3DSA:3.40.50.300 8 222 3.2E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21400 8797e2b657fc3e40a9faae28fa54bb61 229 SUPERFAMILY SSF52540 8 225 4.31E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21400 8797e2b657fc3e40a9faae28fa54bb61 229 Pfam PF00005 ABC transporter 24 172 1.1E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS26530 a5360a07481f5174082cbab3d9d3cdf5 482 Gene3D G3DSA:3.40.190.10 192 391 3.5E-30 T 06-07-2017 LK06_RS26530 a5360a07481f5174082cbab3d9d3cdf5 482 Pfam PF01547 Bacterial extracellular solute-binding protein 94 383 1.9E-17 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 LK06_RS26530 a5360a07481f5174082cbab3d9d3cdf5 482 SUPERFAMILY SSF53850 38 473 2.47E-53 T 06-07-2017 LK06_RS26530 a5360a07481f5174082cbab3d9d3cdf5 482 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 32 478 1.1E-162 T 06-07-2017 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding LK06_RS20915 f1d16193bc5836b0eaf9fab6c0c7653b 482 Pfam PF02687 FtsX-like permease family 324 472 4.1E-16 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS09250 b1ae265f5ca337dc86f792622ec9fde7 408 ProSitePatterns PS01125 ROK family signature. 230 257 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS09250 b1ae265f5ca337dc86f792622ec9fde7 408 SUPERFAMILY SSF46785 22 83 7.45E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09250 b1ae265f5ca337dc86f792622ec9fde7 408 Gene3D G3DSA:1.10.10.10 22 83 3.6E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09250 b1ae265f5ca337dc86f792622ec9fde7 408 Gene3D G3DSA:3.30.420.40 235 376 3.9E-38 T 06-07-2017 LK06_RS09250 b1ae265f5ca337dc86f792622ec9fde7 408 Gene3D G3DSA:3.30.420.40 87 234 4.8E-44 T 06-07-2017 LK06_RS09250 b1ae265f5ca337dc86f792622ec9fde7 408 SUPERFAMILY SSF53067 90 392 1.6E-48 T 06-07-2017 LK06_RS09250 b1ae265f5ca337dc86f792622ec9fde7 408 Pfam PF00480 ROK family 94 390 2.0E-48 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS15020 2ea442037385f6e51e71e82632aba221 524 Pfam PF00361 Proton-conducting membrane transporter 161 451 5.3E-45 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15020 2ea442037385f6e51e71e82632aba221 524 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 415 441 9.2E-5 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15020 2ea442037385f6e51e71e82632aba221 524 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 274 298 9.2E-5 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15020 2ea442037385f6e51e71e82632aba221 524 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 363 382 9.2E-5 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS26175 b23261ea48abe006788e47782796e758 604 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 66 366 2.4E-26 T 06-07-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 LK06_RS26175 b23261ea48abe006788e47782796e758 604 SUPERFAMILY SSF51445 11 380 1.73E-44 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS26175 b23261ea48abe006788e47782796e758 604 Gene3D G3DSA:3.20.20.80 8 380 8.1E-62 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS18305 796fca2bd14ac8df621e3434ae5d1688 373 Gene3D G3DSA:3.20.20.70 9 360 1.1E-100 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS18305 796fca2bd14ac8df621e3434ae5d1688 373 SUPERFAMILY SSF51395 10 357 6.11E-94 T 06-07-2017 LK06_RS18305 796fca2bd14ac8df621e3434ae5d1688 373 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 16 357 1.5E-61 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 LK06_RS31730 6dc58a9c8ade5ba2b15b100d97e03f0e 447 SUPERFAMILY SSF53383 38 435 1.01E-70 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS31730 6dc58a9c8ade5ba2b15b100d97e03f0e 447 Gene3D G3DSA:3.40.640.10 83 318 3.4E-65 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS31730 6dc58a9c8ade5ba2b15b100d97e03f0e 447 Pfam PF00155 Aminotransferase class I and II 87 431 8.4E-22 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS31730 6dc58a9c8ade5ba2b15b100d97e03f0e 447 Gene3D G3DSA:3.90.1150.10 356 435 3.7E-7 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS32080 3ce4a5a29cce9e615a6a16c6a7edcfd8 197 Pfam PF01227 GTP cyclohydrolase I 28 195 4.0E-53 T 06-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 LK06_RS32080 3ce4a5a29cce9e615a6a16c6a7edcfd8 197 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 124 134 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 LK06_RS32080 3ce4a5a29cce9e615a6a16c6a7edcfd8 197 Gene3D G3DSA:1.10.286.10 26 58 3.0E-13 T 06-07-2017 LK06_RS32080 3ce4a5a29cce9e615a6a16c6a7edcfd8 197 Gene3D G3DSA:3.30.1130.10 70 196 4.3E-44 T 06-07-2017 LK06_RS32080 3ce4a5a29cce9e615a6a16c6a7edcfd8 197 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 19 196 28.487 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 LK06_RS32080 3ce4a5a29cce9e615a6a16c6a7edcfd8 197 SUPERFAMILY SSF55620 21 196 2.22E-54 T 06-07-2017 LK06_RS13855 b56a9a822daebdf9cb039386b8a1dcc9 184 Gene3D G3DSA:1.20.120.450 6 168 1.3E-42 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase LK06_RS13855 b56a9a822daebdf9cb039386b8a1dcc9 184 Pfam PF04978 Protein of unknown function (DUF664) 17 166 2.0E-48 T 06-07-2017 IPR007061 Protein of unknown function DUF664 LK06_RS13855 b56a9a822daebdf9cb039386b8a1dcc9 184 SUPERFAMILY SSF109854 5 165 3.05E-39 T 06-07-2017 LK06_RS12215 bb3b9001478daf814a79e89c106f78a7 151 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 9 150 18.788 T 06-07-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 LK06_RS12215 bb3b9001478daf814a79e89c106f78a7 151 ProSitePatterns PS00475 Ribosomal protein L15 signature. 114 144 - T 06-07-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS12215 bb3b9001478daf814a79e89c106f78a7 151 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 32 148 7.1E-33 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P LK06_RS12215 bb3b9001478daf814a79e89c106f78a7 151 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 8 147 4.3E-45 T 06-07-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12215 bb3b9001478daf814a79e89c106f78a7 151 SUPERFAMILY SSF52080 10 149 4.45E-40 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P LK06_RS12215 bb3b9001478daf814a79e89c106f78a7 151 Gene3D G3DSA:3.100.10.10 37 150 4.9E-32 T 06-07-2017 LK06_RS19725 5316a44604f50d9733ceb15ea2e883c4 583 Pfam PF13360 PQQ-like domain 198 319 2.6E-10 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat LK06_RS19725 5316a44604f50d9733ceb15ea2e883c4 583 SUPERFAMILY SSF50998 200 504 1.49E-13 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 Pfam PF07503 HypF finger 113 145 2.4E-14 T 06-07-2017 IPR011125 Zinc finger, HypF-type GO:0008270 LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 Pfam PF07503 HypF finger 163 196 2.2E-17 T 06-07-2017 IPR011125 Zinc finger, HypF-type GO:0008270 LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 Pfam PF00708 Acylphosphatase 10 96 2.1E-18 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 Pfam PF01300 Telomere recombination 218 400 4.1E-49 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 SUPERFAMILY SSF55821 180 408 6.1E-41 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 Gene3D G3DSA:3.30.70.100 10 96 8.9E-24 T 06-07-2017 LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 SUPERFAMILY SSF54975 8 96 8.72E-23 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 ProSitePatterns PS00150 Acylphosphatase signature 1. 15 25 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 Gene3D G3DSA:3.90.870.10 208 390 7.3E-40 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 13 796 1.9E-217 T 06-07-2017 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 LK06_RS31265 ccc38a3426e86787a263020c6f395fb9 806 PIRSF PIRSF006256 7 806 7.3E-271 T 06-07-2017 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 LK06_RS21205 cdd5b3fcb8f055a4b6d8ea996e1d9549 431 Gene3D G3DSA:3.20.20.10 151 272 1.2E-11 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS21205 cdd5b3fcb8f055a4b6d8ea996e1d9549 431 SUPERFAMILY SSF51419 65 277 8.9E-23 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS21205 cdd5b3fcb8f055a4b6d8ea996e1d9549 431 Pfam PF01168 Alanine racemase, N-terminal domain 64 268 1.4E-10 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS21205 cdd5b3fcb8f055a4b6d8ea996e1d9549 431 SMART SM01119 322 418 7.4E-30 T 06-07-2017 IPR026956 D-serine dehydratase-like domain LK06_RS21205 cdd5b3fcb8f055a4b6d8ea996e1d9549 431 Pfam PF14031 Putative serine dehydratase domain 322 416 3.3E-14 T 06-07-2017 IPR026956 D-serine dehydratase-like domain LK06_RS04500 4c60c956a418a3d6f7b7f9eaccb19800 274 SUPERFAMILY SSF55729 128 267 4.29E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS04500 4c60c956a418a3d6f7b7f9eaccb19800 274 Gene3D G3DSA:3.40.630.30 8 105 1.8E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS04500 4c60c956a418a3d6f7b7f9eaccb19800 274 Pfam PF00583 Acetyltransferase (GNAT) family 188 263 4.9E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS04500 4c60c956a418a3d6f7b7f9eaccb19800 274 Pfam PF00583 Acetyltransferase (GNAT) family 28 105 9.1E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS04500 4c60c956a418a3d6f7b7f9eaccb19800 274 SUPERFAMILY SSF55729 20 108 8.72E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS04500 4c60c956a418a3d6f7b7f9eaccb19800 274 Gene3D G3DSA:3.40.630.30 129 267 1.5E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS08035 d845bbb70129874d8438fd114d4e2478 285 SUPERFAMILY SSF53474 21 283 6.46E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08035 d845bbb70129874d8438fd114d4e2478 285 Gene3D G3DSA:3.40.50.1820 12 283 3.1E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08035 d845bbb70129874d8438fd114d4e2478 285 Pfam PF12697 Alpha/beta hydrolase family 49 271 1.3E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS17470 08e2ba78229a341fc2544e2c7f6e4e4f 314 Pfam PF03756 A-factor biosynthesis hotdog domain 204 284 1.3E-15 T 06-07-2017 IPR005509 A-factor biosynthesis hotdog domain LK06_RS17470 08e2ba78229a341fc2544e2c7f6e4e4f 314 Pfam PF03756 A-factor biosynthesis hotdog domain 30 166 1.7E-31 T 06-07-2017 IPR005509 A-factor biosynthesis hotdog domain LK06_RS12075 e63b0f3ccccb18352053a2159cfeb12c 391 SUPERFAMILY SSF51338 23 67 7.56E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS12075 e63b0f3ccccb18352053a2159cfeb12c 391 SUPERFAMILY SSF51338 350 389 7.56E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS12075 e63b0f3ccccb18352053a2159cfeb12c 391 SUPERFAMILY SSF51556 66 349 2.72E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS12075 e63b0f3ccccb18352053a2159cfeb12c 391 TIGRFAM TIGR01224 hutI: imidazolonepropionase 30 388 6.8E-111 T 06-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LK06_RS12075 e63b0f3ccccb18352053a2159cfeb12c 391 Gene3D G3DSA:2.30.40.10 13 77 1.6E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS12075 e63b0f3ccccb18352053a2159cfeb12c 391 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 390 43.226 T 06-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LK06_RS12075 e63b0f3ccccb18352053a2159cfeb12c 391 Gene3D G3DSA:3.20.20.140 78 367 1.7E-44 T 06-07-2017 LK06_RS12075 e63b0f3ccccb18352053a2159cfeb12c 391 Pfam PF01979 Amidohydrolase family 243 368 2.4E-16 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS25250 ddca24fe8d7ea8ac2b242f506a1795d1 514 Pfam PF13830 Domain of unknown function (DUF4192) 33 378 2.6E-91 T 06-07-2017 IPR025447 Protein of unknown function DUF4192 LK06_RS06755 90bfa4e9e0ffea266caf3ed9fe862637 231 Pfam PF10056 Uncharacterized conserved protein (DUF2293) 139 224 7.9E-23 T 06-07-2017 IPR018744 Domain of unknown function DUF2293 LK06_RS06735 ebc1a9383dd6a4509c191d8e89b6adc8 332 Gene3D G3DSA:3.40.1190.20 14 306 5.2E-63 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS06735 ebc1a9383dd6a4509c191d8e89b6adc8 332 SUPERFAMILY SSF53613 14 307 6.7E-62 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS06735 ebc1a9383dd6a4509c191d8e89b6adc8 332 Pfam PF00294 pfkB family carbohydrate kinase 14 306 4.6E-50 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB LK06_RS06735 ebc1a9383dd6a4509c191d8e89b6adc8 332 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 261 274 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 SMART SM00889 519 637 2.6E-58 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 Gene3D G3DSA:2.40.30.10 330 443 2.4E-29 T 06-07-2017 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 SUPERFAMILY SSF54980 640 729 5.76E-21 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 Gene3D G3DSA:3.40.50.300 19 313 8.0E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 SUPERFAMILY SSF54980 443 520 3.96E-17 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 Gene3D G3DSA:3.30.70.240 639 725 4.8E-22 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 Gene3D G3DSA:3.30.70.870 444 515 3.3E-24 T 06-07-2017 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 Pfam PF03144 Elongation factor Tu domain 2 350 429 1.1E-10 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 PRINTS PR00315 GTP-binding elongation factor signature 26 39 5.1E-6 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 PRINTS PR00315 GTP-binding elongation factor signature 92 102 5.1E-6 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 PRINTS PR00315 GTP-binding elongation factor signature 108 119 5.1E-6 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 SMART SM00838 639 727 6.9E-19 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 Pfam PF14492 Elongation Factor G, domain II 443 515 4.9E-24 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 SUPERFAMILY SSF54211 519 637 4.8E-36 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 Gene3D G3DSA:3.30.230.10 523 638 1.6E-48 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 Pfam PF00009 Elongation factor Tu GTP binding domain 24 212 1.8E-30 T 06-07-2017 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 SUPERFAMILY SSF52540 21 307 1.5E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 Pfam PF03764 Elongation factor G, domain IV 519 637 1.4E-40 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 SUPERFAMILY SSF50447 320 440 5.3E-23 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 155 2.2E-15 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 LK06_RS04335 94a69a157ca86575f09302f667d2b980 735 Pfam PF00679 Elongation factor G C-terminus 640 726 8.9E-21 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS31425 c1e7ce4697fc9806f1a5a642b54b230d 205 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 40 147 1.8E-24 T 06-07-2017 IPR018641 Transferase 1, rSAM/selenodomain-associated LK06_RS31425 c1e7ce4697fc9806f1a5a642b54b230d 205 Gene3D G3DSA:3.90.550.10 4 167 2.7E-26 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS31425 c1e7ce4697fc9806f1a5a642b54b230d 205 SUPERFAMILY SSF53448 6 187 2.39E-30 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS02485 096b0a3ea2bff2a355526c2db4298de9 183 Gene3D G3DSA:2.30.110.10 29 181 7.1E-52 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS02485 096b0a3ea2bff2a355526c2db4298de9 183 SMART SM00903 33 180 8.4E-57 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS02485 096b0a3ea2bff2a355526c2db4298de9 183 SUPERFAMILY SSF50475 28 181 1.67E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS02485 096b0a3ea2bff2a355526c2db4298de9 183 Pfam PF01613 Flavin reductase like domain 34 181 1.2E-36 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS12440 672af09ffd8dfa549657881346d58178 176 Pfam PF00466 Ribosomal protein L10 2 98 1.1E-25 T 06-07-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 LK06_RS12440 672af09ffd8dfa549657881346d58178 176 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 06-07-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS12440 672af09ffd8dfa549657881346d58178 176 SUPERFAMILY SSF160369 1 168 8.11E-52 T 06-07-2017 LK06_RS12440 672af09ffd8dfa549657881346d58178 176 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.471 T 06-07-2017 IPR022973 Ribosomal protein L10 LK06_RS12955 a05ffe8524f5e66947f70a9cc320e6e7 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 118 1.9E-36 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12955 a05ffe8524f5e66947f70a9cc320e6e7 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 119 17.824 T 06-07-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 LK06_RS23770 e5c880300a33cd43e844e2deb33cdc9c 335 Gene3D G3DSA:1.10.3720.10 117 331 1.2E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS23770 e5c880300a33cd43e844e2deb33cdc9c 335 SUPERFAMILY SSF161098 119 316 2.49E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS23770 e5c880300a33cd43e844e2deb33cdc9c 335 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 34 71 4.5E-11 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LK06_RS23770 e5c880300a33cd43e844e2deb33cdc9c 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 332 3.3E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS04270 fd05cfaa36619213a5498d9a30a72af9 575 Pfam PF02355 Protein export membrane protein 355 531 2.2E-12 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial LK06_RS04270 fd05cfaa36619213a5498d9a30a72af9 575 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 541 36.95 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 LK06_RS04270 fd05cfaa36619213a5498d9a30a72af9 575 Gene3D G3DSA:1.20.1640.10 365 535 6.8E-21 T 06-07-2017 LK06_RS04270 fd05cfaa36619213a5498d9a30a72af9 575 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 17 527 1.4E-105 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 LK06_RS04270 fd05cfaa36619213a5498d9a30a72af9 575 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 281 519 5.8E-68 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LK06_RS04270 fd05cfaa36619213a5498d9a30a72af9 575 SUPERFAMILY SSF82866 333 534 9.94E-37 T 06-07-2017 LK06_RS07315 3b4803a63b805a8d09121e52bb6a8bc6 362 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 355 24.158 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LK06_RS07315 3b4803a63b805a8d09121e52bb6a8bc6 362 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LK06_RS07315 3b4803a63b805a8d09121e52bb6a8bc6 362 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 351 1.9E-98 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LK06_RS07315 3b4803a63b805a8d09121e52bb6a8bc6 362 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 8.2E-6 T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LK06_RS07315 3b4803a63b805a8d09121e52bb6a8bc6 362 Pfam PF00953 Glycosyl transferase family 4 88 281 1.9E-36 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 LK06_RS07315 3b4803a63b805a8d09121e52bb6a8bc6 362 ProSitePatterns PS01348 MraY family signature 2. 180 191 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LK06_RS11525 1dfacd9fd2b60ee76fc640c1379df49b 338 Gene3D G3DSA:3.40.109.10 243 335 1.1E-21 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS11525 1dfacd9fd2b60ee76fc640c1379df49b 338 Gene3D G3DSA:3.40.109.10 14 82 1.1E-21 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS11525 1dfacd9fd2b60ee76fc640c1379df49b 338 SUPERFAMILY SSF55469 14 90 9.55E-9 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS11525 1dfacd9fd2b60ee76fc640c1379df49b 338 Pfam PF00881 Nitroreductase family 130 319 4.7E-5 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 LK06_RS11525 1dfacd9fd2b60ee76fc640c1379df49b 338 SUPERFAMILY SSF55469 126 191 5.3E-9 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS11525 1dfacd9fd2b60ee76fc640c1379df49b 338 SUPERFAMILY SSF55469 240 331 5.3E-9 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS07520 acbe6a174a37de0f5144f123defc668b 263 SUPERFAMILY SSF56219 14 243 3.8E-26 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS07520 acbe6a174a37de0f5144f123defc668b 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 20 236 2.5E-12 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS07520 acbe6a174a37de0f5144f123defc668b 263 Gene3D G3DSA:3.60.10.10 16 243 2.6E-7 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS16720 14c506e039ba09a7762d37c08a973912 98 PIRSF PIRSF006909 1 98 3.1E-58 T 06-07-2017 IPR014447 Uncharacterised conserved protein UCP006909 LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 Pfam PF00709 Adenylosuccinate synthetase 5 421 4.2E-178 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 423 1.9E-167 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 Gene3D G3DSA:3.40.440.10 4 93 2.8E-71 T 06-07-2017 LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 Gene3D G3DSA:3.40.440.10 195 264 2.8E-71 T 06-07-2017 LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 SUPERFAMILY SSF52540 3 425 3.08E-174 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 Gene3D G3DSA:1.10.300.10 101 194 4.0E-33 T 06-07-2017 LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 06-07-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 06-07-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 Gene3D G3DSA:3.90.170.10 266 422 2.1E-69 T 06-07-2017 LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 SMART SM00788 3 422 4.9E-286 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 LK06_RS14545 03a2c34768d858d9c1c54dfb227c901f 427 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 427 200.753 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 LK06_RS01380 1206984f8564e905d92bf7a37ae85ab0 422 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 2 415 2.7E-92 T 06-07-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 LK06_RS01380 1206984f8564e905d92bf7a37ae85ab0 422 Pfam PF00999 Sodium/hydrogen exchanger family 1 293 2.3E-37 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 LK06_RS28125 c70f46cab5f3366f9c9f472a8d502df7 464 SUPERFAMILY SSF53383 51 412 5.01E-36 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS28125 c70f46cab5f3366f9c9f472a8d502df7 464 Pfam PF00155 Aminotransferase class I and II 80 260 1.8E-10 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS28125 c70f46cab5f3366f9c9f472a8d502df7 464 Gene3D G3DSA:3.40.640.10 88 260 1.6E-21 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS17845 00108de333f639cccb570a9b1d6582a2 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 9.4E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS17845 00108de333f639cccb570a9b1d6582a2 226 Gene3D G3DSA:3.40.50.2300 3 121 6.9E-40 T 06-07-2017 LK06_RS17845 00108de333f639cccb570a9b1d6582a2 226 SUPERFAMILY SSF46894 125 225 1.76E-31 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS17845 00108de333f639cccb570a9b1d6582a2 226 SMART SM00448 2 112 1.7E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS17845 00108de333f639cccb570a9b1d6582a2 226 Gene3D G3DSA:1.10.10.10 128 225 2.5E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17845 00108de333f639cccb570a9b1d6582a2 226 SMART SM00862 148 224 6.0E-30 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS17845 00108de333f639cccb570a9b1d6582a2 226 Pfam PF00072 Response regulator receiver domain 4 113 7.1E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS17845 00108de333f639cccb570a9b1d6582a2 226 SUPERFAMILY SSF52172 3 124 6.12E-41 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS22840 5d694cc7263af269d3ed96dcc82ed29c 187 Pfam PF01106 NifU-like domain 101 164 1.4E-11 T 06-07-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 LK06_RS22840 5d694cc7263af269d3ed96dcc82ed29c 187 SUPERFAMILY SSF117916 92 167 2.09E-13 T 06-07-2017 LK06_RS22840 5d694cc7263af269d3ed96dcc82ed29c 187 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 111 163 2.0E-5 T 06-07-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 LK06_RS23345 e15ec9d5677a389df62f9df3b6f2ffa7 190 Pfam PF01923 Cobalamin adenosyltransferase 7 174 1.4E-52 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 LK06_RS23345 e15ec9d5677a389df62f9df3b6f2ffa7 190 Gene3D G3DSA:1.20.1200.10 16 187 3.5E-55 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 LK06_RS23345 e15ec9d5677a389df62f9df3b6f2ffa7 190 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 13 184 6.0E-88 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 LK06_RS23345 e15ec9d5677a389df62f9df3b6f2ffa7 190 SUPERFAMILY SSF89028 6 185 1.12E-54 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 LK06_RS23345 e15ec9d5677a389df62f9df3b6f2ffa7 190 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 180 1.6E-48 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 LK06_RS19925 e11a9e1be783c046f7c198b8749c7aec 340 SUPERFAMILY SSF53790 36 108 2.47E-7 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS19925 e11a9e1be783c046f7c198b8749c7aec 340 SUPERFAMILY SSF101386 139 237 1.24E-21 T 06-07-2017 LK06_RS19925 e11a9e1be783c046f7c198b8749c7aec 340 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 157 232 1.0E-25 T 06-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core LK06_RS19925 e11a9e1be783c046f7c198b8749c7aec 340 Gene3D G3DSA:1.10.287.1080 139 208 2.5E-11 T 06-07-2017 LK06_RS15600 051987cb99c53076a04f8c70642d28b3 359 Pfam PF04203 Sortase family 207 344 9.7E-27 T 06-07-2017 IPR005754 Sortase family LK06_RS15600 051987cb99c53076a04f8c70642d28b3 359 Gene3D G3DSA:2.40.260.10 202 347 1.5E-28 T 06-07-2017 IPR023365 Sortase domain LK06_RS15600 051987cb99c53076a04f8c70642d28b3 359 SUPERFAMILY SSF63817 199 345 1.7E-30 T 06-07-2017 IPR023365 Sortase domain LK06_RS15600 051987cb99c53076a04f8c70642d28b3 359 TIGRFAM TIGR01076 sortase_fam: sortase 206 345 1.8E-15 T 06-07-2017 IPR005754 Sortase family LK06_RS29980 a8f3c02ff9806d55d07ec8ea40f7591a 347 SUPERFAMILY SSF52540 3 182 7.64E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29980 a8f3c02ff9806d55d07ec8ea40f7591a 347 PRINTS PR00502 NUDIX hydrolase family signature 227 241 8.6E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS29980 a8f3c02ff9806d55d07ec8ea40f7591a 347 PRINTS PR00502 NUDIX hydrolase family signature 241 256 8.6E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS29980 a8f3c02ff9806d55d07ec8ea40f7591a 347 Pfam PF13671 AAA domain 3 130 6.6E-8 T 06-07-2017 LK06_RS29980 a8f3c02ff9806d55d07ec8ea40f7591a 347 SUPERFAMILY SSF55811 201 331 2.17E-22 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS29980 a8f3c02ff9806d55d07ec8ea40f7591a 347 Gene3D G3DSA:3.40.50.300 3 182 2.7E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29980 a8f3c02ff9806d55d07ec8ea40f7591a 347 Gene3D G3DSA:3.90.79.10 203 331 5.8E-22 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS29980 a8f3c02ff9806d55d07ec8ea40f7591a 347 Pfam PF00293 NUDIX domain 203 327 1.4E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 Gene3D G3DSA:3.40.50.2300 13 163 1.4E-36 T 06-07-2017 LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 SMART SM00448 14 127 3.8E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 Pfam PF00072 Response regulator receiver domain 16 127 3.7E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 3.1E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 3.1E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 3.1E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 SUPERFAMILY SSF52172 13 142 4.55E-30 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 SMART SM00421 161 218 1.1E-26 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 Gene3D G3DSA:1.10.10.10 164 221 1.7E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 218 1.3E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS30180 be498176ac2cbbc6cb67064eda584628 230 SUPERFAMILY SSF46894 154 220 1.09E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS20340 73490c61aa655870a5abfd1c10e81f30 405 SUPERFAMILY SSF88946 145 230 1.96E-9 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20340 73490c61aa655870a5abfd1c10e81f30 405 Gene3D G3DSA:1.10.10.10 232 290 4.6E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20340 73490c61aa655870a5abfd1c10e81f30 405 Gene3D G3DSA:1.10.1740.10 145 214 1.6E-8 T 06-07-2017 LK06_RS20340 73490c61aa655870a5abfd1c10e81f30 405 Pfam PF01381 Helix-turn-helix 34 70 4.8E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS20340 73490c61aa655870a5abfd1c10e81f30 405 SUPERFAMILY SSF88659 233 288 2.8E-6 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20340 73490c61aa655870a5abfd1c10e81f30 405 SMART SM00530 32 86 6.9E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS20340 73490c61aa655870a5abfd1c10e81f30 405 SUPERFAMILY SSF47413 34 71 4.02E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS20340 73490c61aa655870a5abfd1c10e81f30 405 Gene3D G3DSA:1.10.260.40 34 70 6.9E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS21005 16d604c97e163f9008c06544c72fcc22 293 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 290 51.347 T 06-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 LK06_RS21005 16d604c97e163f9008c06544c72fcc22 293 Gene3D G3DSA:3.40.50.10320 4 291 2.0E-81 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 LK06_RS21005 16d604c97e163f9008c06544c72fcc22 293 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 289 5.4E-149 T 06-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 LK06_RS21005 16d604c97e163f9008c06544c72fcc22 293 SUPERFAMILY SSF102588 4 291 4.71E-71 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 LK06_RS21005 16d604c97e163f9008c06544c72fcc22 293 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 154 4.9E-25 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 LK06_RS27535 18a9638da5c23cbe28c7fe74cdd1c439 263 Pfam PF01614 Bacterial transcriptional regulator 134 256 2.0E-30 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal LK06_RS27535 18a9638da5c23cbe28c7fe74cdd1c439 263 Pfam PF09339 IclR helix-turn-helix domain 21 72 9.5E-18 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS27535 18a9638da5c23cbe28c7fe74cdd1c439 263 Gene3D G3DSA:1.10.10.10 17 91 3.6E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27535 18a9638da5c23cbe28c7fe74cdd1c439 263 Gene3D G3DSA:3.30.450.40 93 258 3.0E-60 T 06-07-2017 IPR029016 GAF domain-like LK06_RS27535 18a9638da5c23cbe28c7fe74cdd1c439 263 SUPERFAMILY SSF55781 76 258 2.42E-50 T 06-07-2017 IPR029016 GAF domain-like LK06_RS27535 18a9638da5c23cbe28c7fe74cdd1c439 263 SUPERFAMILY SSF46785 19 89 2.99E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27535 18a9638da5c23cbe28c7fe74cdd1c439 263 SMART SM00346 19 106 1.5E-22 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS27655 6421d63e3b9c55db633642b3301993e7 340 Gene3D G3DSA:3.40.50.720 27 165 6.4E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27655 6421d63e3b9c55db633642b3301993e7 340 SUPERFAMILY SSF51735 26 177 6.47E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27655 6421d63e3b9c55db633642b3301993e7 340 Gene3D G3DSA:3.30.360.10 166 339 8.0E-22 T 06-07-2017 LK06_RS27655 6421d63e3b9c55db633642b3301993e7 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 32 138 3.4E-9 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 LK06_RS27655 6421d63e3b9c55db633642b3301993e7 340 SUPERFAMILY SSF55347 150 306 3.92E-21 T 06-07-2017 LK06_RS09425 971c736361ff5eb36185000c0f0d4f75 117 SUPERFAMILY SSF53927 12 108 6.02E-10 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 LK06_RS09425 971c736361ff5eb36185000c0f0d4f75 117 Gene3D G3DSA:3.40.140.10 14 82 5.9E-7 T 06-07-2017 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 SUPERFAMILY SSF101904 514 834 6.28E-100 T 06-07-2017 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Gene3D G3DSA:3.30.1360.40 252 348 3.3E-34 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 20 827 0.0 T 06-07-2017 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Gene3D G3DSA:2.120.10.90 512 826 2.4E-119 T 06-07-2017 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 626 661 4.9E-8 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 781 825 2.8E-11 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 519 564 3.1E-14 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 732 777 1.7E-12 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 678 726 3.3E-11 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 570 613 6.3E-9 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Gene3D G3DSA:3.90.199.10 42 251 8.6E-114 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Gene3D G3DSA:3.90.199.10 349 413 8.6E-114 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 SMART SM00434 23 480 3.6E-286 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 4 829 23.173 T 06-07-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 SUPERFAMILY SSF56719 42 502 2.75E-171 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 LK06_RS15825 036d2c17ef190d11f5f3030b743c2339 864 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 44 486 1.7E-150 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LK06_RS18880 f1594c9743ed1a3d6446b73fc6c6e77e 222 SUPERFAMILY SSF50475 26 222 1.51E-44 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS18880 f1594c9743ed1a3d6446b73fc6c6e77e 222 PIRSF PIRSF000190 3 222 2.0E-58 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS18880 f1594c9743ed1a3d6446b73fc6c6e77e 222 Gene3D G3DSA:2.30.110.10 27 222 5.9E-57 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS18880 f1594c9743ed1a3d6446b73fc6c6e77e 222 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 182 222 5.7E-11 T 06-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS18880 f1594c9743ed1a3d6446b73fc6c6e77e 222 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 45 125 2.4E-17 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS01930 5ad7d71c132958d2b1e2feaf98d5cb7d 414 Pfam PF01593 Flavin containing amine oxidoreductase 19 409 5.6E-36 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 LK06_RS01930 5ad7d71c132958d2b1e2feaf98d5cb7d 414 SUPERFAMILY SSF51905 375 413 1.47E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01930 5ad7d71c132958d2b1e2feaf98d5cb7d 414 SUPERFAMILY SSF51905 8 290 1.47E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01930 5ad7d71c132958d2b1e2feaf98d5cb7d 414 Gene3D G3DSA:3.50.50.60 209 279 5.9E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01930 5ad7d71c132958d2b1e2feaf98d5cb7d 414 Gene3D G3DSA:3.50.50.60 373 413 5.9E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01930 5ad7d71c132958d2b1e2feaf98d5cb7d 414 Gene3D G3DSA:3.50.50.60 11 48 5.9E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19270 f967fd54f9755f842ea9286a9120ae12 169 Gene3D G3DSA:1.10.10.10 7 158 8.5E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19270 f967fd54f9755f842ea9286a9120ae12 169 SUPERFAMILY SSF46785 9 156 6.47E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS19270 f967fd54f9755f842ea9286a9120ae12 169 SMART SM00347 39 142 1.6E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19270 f967fd54f9755f842ea9286a9120ae12 169 Pfam PF12802 MarR family 45 105 2.4E-12 T 06-07-2017 LK06_RS19270 f967fd54f9755f842ea9286a9120ae12 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 97 4.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19270 f967fd54f9755f842ea9286a9120ae12 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 101 117 4.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19270 f967fd54f9755f842ea9286a9120ae12 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 132 152 4.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS19270 f967fd54f9755f842ea9286a9120ae12 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 81 4.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS16830 d82eeb7bdaab4da1ce16b5ad65950dd0 90 SUPERFAMILY SSF46785 1 59 9.99E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16830 d82eeb7bdaab4da1ce16b5ad65950dd0 90 Gene3D G3DSA:1.10.10.10 1 59 1.2E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS04505 428fda54c7a520e821c299b8da2cd125 273 SUPERFAMILY SSF56752 3 264 1.57E-68 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 LK06_RS04505 428fda54c7a520e821c299b8da2cd125 273 ProSitePatterns PS00770 Aminotransferases class-IV signature. 174 203 - T 06-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 LK06_RS04505 428fda54c7a520e821c299b8da2cd125 273 Gene3D G3DSA:3.30.470.10 1 101 2.9E-32 T 06-07-2017 LK06_RS04505 428fda54c7a520e821c299b8da2cd125 273 Gene3D G3DSA:3.20.10.10 124 258 8.3E-41 T 06-07-2017 LK06_RS04505 428fda54c7a520e821c299b8da2cd125 273 Pfam PF01063 Amino-transferase class IV 29 242 6.0E-49 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 LK06_RS09445 5b5feec5949257b5e14f3eba4e4600f1 165 Gene3D G3DSA:3.40.390.30 5 156 5.8E-42 T 06-07-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 LK06_RS09445 5b5feec5949257b5e14f3eba4e4600f1 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 119 129 - T 06-07-2017 IPR020549 Endoribonuclease YbeY, conserved site LK06_RS09445 5b5feec5949257b5e14f3eba4e4600f1 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 157 21.127 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 LK06_RS09445 5b5feec5949257b5e14f3eba4e4600f1 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 1.9E-30 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 LK06_RS09445 5b5feec5949257b5e14f3eba4e4600f1 165 SUPERFAMILY SSF55486 3 149 9.52E-37 T 06-07-2017 LK06_RS09445 5b5feec5949257b5e14f3eba4e4600f1 165 Pfam PF02130 Uncharacterized protein family UPF0054 16 147 3.7E-35 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 LK06_RS29035 87ab299f4706471e90df960c85a53628 302 SUPERFAMILY SSF52540 22 250 9.5E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29035 87ab299f4706471e90df960c85a53628 302 SMART SM00382 48 241 2.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS29035 87ab299f4706471e90df960c85a53628 302 Gene3D G3DSA:3.40.50.300 20 251 6.4E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29035 87ab299f4706471e90df960c85a53628 302 Pfam PF00005 ABC transporter 39 193 2.1E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS29035 87ab299f4706471e90df960c85a53628 302 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS21470 bf9477a6ad53ba47ebea0537c21eade9 562 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 380 543 1.8E-58 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 LK06_RS21470 bf9477a6ad53ba47ebea0537c21eade9 562 PIRSF PIRSF001394 35 557 1.5E-227 T 06-07-2017 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 LK06_RS21470 bf9477a6ad53ba47ebea0537c21eade9 562 SUPERFAMILY SSF117457 368 543 9.42E-62 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 LK06_RS21470 bf9477a6ad53ba47ebea0537c21eade9 562 Gene3D G3DSA:3.20.130.10 358 543 8.1E-75 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 LK06_RS21470 bf9477a6ad53ba47ebea0537c21eade9 562 Pfam PF05681 Fumarate hydratase (Fumerase) 54 331 8.6E-89 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 LK06_RS21470 bf9477a6ad53ba47ebea0537c21eade9 562 ProSitePatterns PS00163 Fumarate lyases signature. 463 472 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 LK06_RS21470 bf9477a6ad53ba47ebea0537c21eade9 562 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 60 332 1.1E-33 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 LK06_RS21470 bf9477a6ad53ba47ebea0537c21eade9 562 Pfam PF05683 Fumarase C-terminus 337 544 1.2E-92 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 LK06_RS16405 8bf4fdd58d99fbc49721e5a5842097b2 451 Gene3D G3DSA:3.40.50.300 156 362 4.1E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16405 8bf4fdd58d99fbc49721e5a5842097b2 451 SUPERFAMILY SSF52540 153 368 1.96E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16405 8bf4fdd58d99fbc49721e5a5842097b2 451 Pfam PF01580 FtsK/SpoIIIE family 140 279 7.8E-30 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS02965 e4e72122fec650b835f298dc0b38907d 208 Pfam PF01205 Uncharacterized protein family UPF0029 20 123 3.0E-29 T 06-07-2017 IPR001498 Impact, N-terminal LK06_RS02965 e4e72122fec650b835f298dc0b38907d 208 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 06-07-2017 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site LK06_RS02965 e4e72122fec650b835f298dc0b38907d 208 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 6.3E-15 T 06-07-2017 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal LK06_RS02965 e4e72122fec650b835f298dc0b38907d 208 SUPERFAMILY SSF54980 138 198 4.68E-15 T 06-07-2017 IPR009022 Elongation factor G, III-V domain LK06_RS02965 e4e72122fec650b835f298dc0b38907d 208 Gene3D G3DSA:3.30.70.240 139 205 3.8E-12 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain LK06_RS02965 e4e72122fec650b835f298dc0b38907d 208 SUPERFAMILY SSF54211 3 130 4.93E-41 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS02965 e4e72122fec650b835f298dc0b38907d 208 Gene3D G3DSA:3.30.230.30 5 131 4.7E-45 T 06-07-2017 IPR001498 Impact, N-terminal LK06_RS02965 e4e72122fec650b835f298dc0b38907d 208 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 195 2.9E-56 T 06-07-2017 IPR015796 Impact family, bacterial/archaeal LK06_RS24380 463abd4c6601e1a9d32cef1ece0581e7 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 06-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 LK06_RS24380 463abd4c6601e1a9d32cef1ece0581e7 112 Gene3D G3DSA:3.30.70.120 1 112 3.0E-45 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal LK06_RS24380 463abd4c6601e1a9d32cef1ece0581e7 112 SUPERFAMILY SSF54913 1 112 3.5E-41 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta LK06_RS24380 463abd4c6601e1a9d32cef1ece0581e7 112 PRINTS PR00340 P-II protein signature 2 17 8.5E-36 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS24380 463abd4c6601e1a9d32cef1ece0581e7 112 PRINTS PR00340 P-II protein signature 83 103 8.5E-36 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS24380 463abd4c6601e1a9d32cef1ece0581e7 112 PRINTS PR00340 P-II protein signature 23 41 8.5E-36 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS24380 463abd4c6601e1a9d32cef1ece0581e7 112 PRINTS PR00340 P-II protein signature 52 75 8.5E-36 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS24380 463abd4c6601e1a9d32cef1ece0581e7 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.1E-38 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS24380 463abd4c6601e1a9d32cef1ece0581e7 112 SMART SM00938 4 105 4.8E-57 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LK06_RS30175 8fcf02518141740580ff3ba95afc76a8 209 Pfam PF07681 DoxX 45 146 1.1E-6 T 06-07-2017 IPR032808 DoxX family LK06_RS12020 97f2a177169b6eb2c6775faf894a1937 386 SUPERFAMILY SSF52440 4 97 5.32E-26 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS12020 97f2a177169b6eb2c6775faf894a1937 386 SUPERFAMILY SSF56059 102 307 6.36E-57 T 06-07-2017 LK06_RS12020 97f2a177169b6eb2c6775faf894a1937 386 Gene3D G3DSA:3.30.1490.20 120 163 9.9E-6 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS12020 97f2a177169b6eb2c6775faf894a1937 386 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 5 366 39.555 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 LK06_RS12020 97f2a177169b6eb2c6775faf894a1937 386 SUPERFAMILY SSF51246 313 381 2.12E-17 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS12020 97f2a177169b6eb2c6775faf894a1937 386 Gene3D G3DSA:3.40.50.20 4 109 1.5E-28 T 06-07-2017 IPR016185 Pre-ATP-grasp domain LK06_RS12020 97f2a177169b6eb2c6775faf894a1937 386 Pfam PF02222 ATP-grasp domain 112 287 4.8E-46 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type LK06_RS12020 97f2a177169b6eb2c6775faf894a1937 386 Gene3D G3DSA:3.30.470.20 164 382 1.7E-80 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS12020 97f2a177169b6eb2c6775faf894a1937 386 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 6 370 2.2E-114 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 LK06_RS16065 25d6848eb88a801baf9e34843da0ac11 381 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 197 211 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LK06_RS16065 25d6848eb88a801baf9e34843da0ac11 381 Gene3D G3DSA:3.90.1150.10 255 378 2.8E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS16065 25d6848eb88a801baf9e34843da0ac11 381 Gene3D G3DSA:3.40.640.10 14 254 1.6E-62 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS16065 25d6848eb88a801baf9e34843da0ac11 381 PIRSF PIRSF001434 6 380 1.4E-106 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LK06_RS16065 25d6848eb88a801baf9e34843da0ac11 381 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 45 376 3.5E-82 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LK06_RS16065 25d6848eb88a801baf9e34843da0ac11 381 SUPERFAMILY SSF53383 45 377 8.48E-82 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS03335 d7487efc537fdc0227705de8ba6717c4 314 Pfam PF00892 EamA-like transporter family 12 151 2.7E-11 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS03335 d7487efc537fdc0227705de8ba6717c4 314 Pfam PF00892 EamA-like transporter family 163 298 1.3E-19 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS03335 d7487efc537fdc0227705de8ba6717c4 314 SUPERFAMILY SSF103481 200 303 2.62E-15 T 06-07-2017 LK06_RS03335 d7487efc537fdc0227705de8ba6717c4 314 SUPERFAMILY SSF103481 48 154 4.05E-11 T 06-07-2017 LK06_RS17675 69d0bb04b1a3e8d5744d2b3013bb214f 321 SUPERFAMILY SSF103025 22 240 3.45E-53 T 06-07-2017 LK06_RS17675 69d0bb04b1a3e8d5744d2b3013bb214f 321 SUPERFAMILY SSF101790 243 307 5.56E-5 T 06-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain LK06_RS17675 69d0bb04b1a3e8d5744d2b3013bb214f 321 Gene3D G3DSA:3.30.70.1400 47 131 2.4E-12 T 06-07-2017 LK06_RS17675 69d0bb04b1a3e8d5744d2b3013bb214f 321 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 224 303 2.1E-8 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 LK06_RS17675 69d0bb04b1a3e8d5744d2b3013bb214f 321 Gene3D G3DSA:2.40.30.110 241 299 6.5E-4 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 LK06_RS17675 69d0bb04b1a3e8d5744d2b3013bb214f 321 Pfam PF01571 Aminomethyltransferase folate-binding domain 15 141 1.9E-18 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal LK06_RS17675 69d0bb04b1a3e8d5744d2b3013bb214f 321 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 187 250 6.8E-20 T 06-07-2017 IPR017703 YgfZ/GcvT conserved site LK06_RS31285 59ebc4dcba2fa7e929c9ab5a527e62b2 118 PIRSF PIRSF004761 1 116 1.7E-30 T 06-07-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 LK06_RS31285 59ebc4dcba2fa7e929c9ab5a527e62b2 118 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 112 1.5E-28 T 06-07-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 LK06_RS31285 59ebc4dcba2fa7e929c9ab5a527e62b2 118 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 114 22.544 T 06-07-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 LK06_RS31285 59ebc4dcba2fa7e929c9ab5a527e62b2 118 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 06-07-2017 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site LK06_RS31285 59ebc4dcba2fa7e929c9ab5a527e62b2 118 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 2 112 1.1E-29 T 06-07-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 LK06_RS10290 f108d214e810a8202776d0a7e331aabc 110 Pfam PF03777 Small secreted domain (DUF320) 23 78 5.5E-30 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS26685 543aa996dce3c07fc833e1fe592d3f6d 284 Pfam PF01522 Polysaccharide deacetylase 68 208 2.8E-24 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS26685 543aa996dce3c07fc833e1fe592d3f6d 284 Gene3D G3DSA:3.20.20.370 67 280 1.1E-42 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS26685 543aa996dce3c07fc833e1fe592d3f6d 284 SUPERFAMILY SSF88713 68 278 9.39E-42 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS17245 14076021db1cadbcb14f839c735db6d3 155 PRINTS PR00502 NUDIX hydrolase family signature 44 58 4.1E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS17245 14076021db1cadbcb14f839c735db6d3 155 PRINTS PR00502 NUDIX hydrolase family signature 58 73 4.1E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS17245 14076021db1cadbcb14f839c735db6d3 155 SUPERFAMILY SSF55811 12 149 1.76E-37 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS17245 14076021db1cadbcb14f839c735db6d3 155 Gene3D G3DSA:3.90.79.10 18 149 2.5E-35 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS17245 14076021db1cadbcb14f839c735db6d3 155 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS17245 14076021db1cadbcb14f839c735db6d3 155 Pfam PF00293 NUDIX domain 19 141 6.5E-21 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS07235 dd106e5976e186ccddb71526e5a0446d 155 Pfam PF13673 Acetyltransferase (GNAT) domain 19 155 1.3E-18 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS07235 dd106e5976e186ccddb71526e5a0446d 155 Gene3D G3DSA:3.40.630.30 8 155 1.3E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS07235 dd106e5976e186ccddb71526e5a0446d 155 SUPERFAMILY SSF55729 4 155 3.77E-42 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS19630 6e32c61c5f5ffae64ddfbafb85cddfa1 300 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 286 9.2E-15 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 LK06_RS19630 6e32c61c5f5ffae64ddfbafb85cddfa1 300 SUPERFAMILY SSF51735 6 162 4.54E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS19630 6e32c61c5f5ffae64ddfbafb85cddfa1 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 162 1.7E-38 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 LK06_RS19630 6e32c61c5f5ffae64ddfbafb85cddfa1 300 PIRSF PIRSF000103 1 295 4.5E-78 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 LK06_RS19630 6e32c61c5f5ffae64ddfbafb85cddfa1 300 SUPERFAMILY SSF48179 166 287 1.36E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS19630 6e32c61c5f5ffae64ddfbafb85cddfa1 300 Gene3D G3DSA:3.40.50.720 3 162 1.4E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS19630 6e32c61c5f5ffae64ddfbafb85cddfa1 300 Gene3D G3DSA:1.10.1040.10 168 286 1.2E-25 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LK06_RS04430 dbd79b2b11bd0bf59d77b1664a32fc9b 231 Pfam PF05063 MT-A70 50 209 6.1E-25 T 06-07-2017 IPR007757 MT-A70-like GO:0006139|GO:0008168 LK06_RS04430 dbd79b2b11bd0bf59d77b1664a32fc9b 231 SUPERFAMILY SSF53335 49 183 5.43E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS08995 d9fa8eaa9053fa9432b83ccd434391fe 550 Pfam PF03169 OPT oligopeptide transporter protein 273 543 2.9E-15 T 06-07-2017 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 LK06_RS11045 6fcff9215a977ed83ac8224d59bf13ac 288 Pfam PF00296 Luciferase-like monooxygenase 138 261 7.4E-6 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS11045 6fcff9215a977ed83ac8224d59bf13ac 288 Pfam PF00296 Luciferase-like monooxygenase 25 110 1.3E-6 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS11045 6fcff9215a977ed83ac8224d59bf13ac 288 Gene3D G3DSA:3.20.20.30 139 287 8.1E-13 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS11045 6fcff9215a977ed83ac8224d59bf13ac 288 Gene3D G3DSA:3.20.20.30 27 129 2.4E-8 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS11045 6fcff9215a977ed83ac8224d59bf13ac 288 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 9 286 4.2E-113 T 06-07-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted LK06_RS11045 6fcff9215a977ed83ac8224d59bf13ac 288 SUPERFAMILY SSF51679 24 280 6.18E-31 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS24985 a85e3c04a6a9109cf6cdcbc4f26a7cb1 490 Pfam PF00919 Uncharacterized protein family UPF0004 7 105 1.8E-31 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 LK06_RS24985 a85e3c04a6a9109cf6cdcbc4f26a7cb1 490 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 179 474 5.0E-79 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 LK06_RS24985 a85e3c04a6a9109cf6cdcbc4f26a7cb1 490 Gene3D G3DSA:2.40.50.140 416 478 1.5E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS24985 a85e3c04a6a9109cf6cdcbc4f26a7cb1 490 Gene3D G3DSA:3.80.30.20 184 412 1.0E-58 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe LK06_RS24985 a85e3c04a6a9109cf6cdcbc4f26a7cb1 490 SMART SM00729 183 401 2.4E-37 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 LK06_RS24985 a85e3c04a6a9109cf6cdcbc4f26a7cb1 490 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 187 207 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 LK06_RS24985 a85e3c04a6a9109cf6cdcbc4f26a7cb1 490 Pfam PF04055 Radical SAM superfamily 189 359 1.1E-17 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS24985 a85e3c04a6a9109cf6cdcbc4f26a7cb1 490 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 5 477 60.004 T 06-07-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 LK06_RS24985 a85e3c04a6a9109cf6cdcbc4f26a7cb1 490 SUPERFAMILY SSF102114 172 405 2.35E-42 T 06-07-2017 LK06_RS24985 a85e3c04a6a9109cf6cdcbc4f26a7cb1 490 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 474 2.3E-117 T 06-07-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 LK06_RS26035 f03761bba61f6654777f1beb5e04ea76 307 Pfam PF00296 Luciferase-like monooxygenase 8 249 9.8E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS26035 f03761bba61f6654777f1beb5e04ea76 307 SUPERFAMILY SSF51679 4 304 1.06E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS26035 f03761bba61f6654777f1beb5e04ea76 307 Gene3D G3DSA:3.20.20.30 8 305 6.3E-75 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS26035 f03761bba61f6654777f1beb5e04ea76 307 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 228 1.2E-91 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c LK06_RS00430 7012e75a5ba2f4524f436ac6faff5bf0 195 Pfam PF00571 CBS domain 38 89 2.4E-4 T 06-07-2017 IPR000644 CBS domain LK06_RS00430 7012e75a5ba2f4524f436ac6faff5bf0 195 Pfam PF00571 CBS domain 105 154 2.4E-7 T 06-07-2017 IPR000644 CBS domain LK06_RS00430 7012e75a5ba2f4524f436ac6faff5bf0 195 SMART SM00116 112 160 2.0E-7 T 06-07-2017 IPR000644 CBS domain LK06_RS00430 7012e75a5ba2f4524f436ac6faff5bf0 195 SMART SM00116 45 93 62.0 T 06-07-2017 IPR000644 CBS domain LK06_RS00430 7012e75a5ba2f4524f436ac6faff5bf0 195 Gene3D G3DSA:3.20.20.70 24 159 2.3E-19 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS00430 7012e75a5ba2f4524f436ac6faff5bf0 195 SUPERFAMILY SSF54631 37 154 3.32E-21 T 06-07-2017 LK06_RS06780 0f8acd102da56fce71eb466978d8a9c9 183 Gene3D G3DSA:3.30.565.10 65 143 1.5E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS06780 0f8acd102da56fce71eb466978d8a9c9 183 SUPERFAMILY SSF55874 67 154 1.44E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS06780 0f8acd102da56fce71eb466978d8a9c9 183 Pfam PF13581 Histidine kinase-like ATPase domain 43 141 8.8E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS27950 17373a21c19fb6af0f07fb16b0cdbb8d 373 SUPERFAMILY SSF101478 25 368 1.07E-42 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 LK06_RS27950 17373a21c19fb6af0f07fb16b0cdbb8d 373 Pfam PF03747 ADP-ribosylglycohydrolase 32 337 2.1E-51 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 LK06_RS23245 ea111ad3f16cfa9fa03c1050a32f57ef 279 SUPERFAMILY SSF53335 8 272 4.37E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS23245 ea111ad3f16cfa9fa03c1050a32f57ef 279 Gene3D G3DSA:1.10.8.10 7 81 2.2E-18 T 06-07-2017 LK06_RS23245 ea111ad3f16cfa9fa03c1050a32f57ef 279 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 2 276 42.954 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 LK06_RS23245 ea111ad3f16cfa9fa03c1050a32f57ef 279 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 24 272 3.6E-73 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 LK06_RS23245 ea111ad3f16cfa9fa03c1050a32f57ef 279 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 179 185 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LK06_RS23245 ea111ad3f16cfa9fa03c1050a32f57ef 279 Gene3D G3DSA:3.40.50.150 83 276 5.9E-57 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS23245 ea111ad3f16cfa9fa03c1050a32f57ef 279 Pfam PF05175 Methyltransferase small domain 112 185 1.0E-11 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 LK06_RS23245 ea111ad3f16cfa9fa03c1050a32f57ef 279 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 23 276 1.4E-49 T 06-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 LK06_RS02425 9431d89738aaed9d21ac54cabdbe3f87 226 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.4E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS02425 9431d89738aaed9d21ac54cabdbe3f87 226 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.4E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS02425 9431d89738aaed9d21ac54cabdbe3f87 226 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.4E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS02425 9431d89738aaed9d21ac54cabdbe3f87 226 SMART SM00422 1 71 5.1E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS02425 9431d89738aaed9d21ac54cabdbe3f87 226 Pfam PF13411 MerR HTH family regulatory protein 1 68 1.3E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS02425 9431d89738aaed9d21ac54cabdbe3f87 226 Gene3D G3DSA:1.10.1660.10 1 124 1.6E-18 T 06-07-2017 LK06_RS02425 9431d89738aaed9d21ac54cabdbe3f87 226 SUPERFAMILY SSF46955 1 90 5.86E-14 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS10865 0f7eee34b9121209ade939d2a53c4104 198 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 192 3.3E-50 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS10865 0f7eee34b9121209ade939d2a53c4104 198 SUPERFAMILY SSF53254 1 196 1.39E-49 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS10865 0f7eee34b9121209ade939d2a53c4104 198 PIRSF PIRSF000709 1 178 5.1E-11 T 06-07-2017 LK06_RS10865 0f7eee34b9121209ade939d2a53c4104 198 SMART SM00855 4 153 2.2E-21 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS10865 0f7eee34b9121209ade939d2a53c4104 198 Gene3D G3DSA:3.40.50.1240 3 197 1.0E-46 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS10285 3a4a20e13469487985bb9cb21b351462 312 Pfam PF01435 Peptidase family M48 117 189 6.8E-8 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LK06_RS10285 3a4a20e13469487985bb9cb21b351462 312 Gene3D G3DSA:3.30.2010.10 103 181 1.8E-11 T 06-07-2017 LK06_RS05540 11a7263bf32c182d3d746c663ab9395b 371 SUPERFAMILY SSF51905 280 363 2.12E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS05540 11a7263bf32c182d3d746c663ab9395b 371 SUPERFAMILY SSF51905 5 163 2.12E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS05540 11a7263bf32c182d3d746c663ab9395b 371 Pfam PF01494 FAD binding domain 4 68 7.9E-7 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS05540 11a7263bf32c182d3d746c663ab9395b 371 Pfam PF01494 FAD binding domain 288 336 3.4E-5 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS05540 11a7263bf32c182d3d746c663ab9395b 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 6.9E-15 T 06-07-2017 LK06_RS05540 11a7263bf32c182d3d746c663ab9395b 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 6.9E-15 T 06-07-2017 LK06_RS05540 11a7263bf32c182d3d746c663ab9395b 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 6.9E-15 T 06-07-2017 LK06_RS05540 11a7263bf32c182d3d746c663ab9395b 371 Gene3D G3DSA:3.50.50.60 272 354 1.7E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS05540 11a7263bf32c182d3d746c663ab9395b 371 Gene3D G3DSA:3.50.50.60 4 168 1.7E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS08490 7ef2b900dc43cf61c194146d0c5963ec 336 SUPERFAMILY SSF51679 1 331 1.05E-57 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS08490 7ef2b900dc43cf61c194146d0c5963ec 336 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 319 1.0E-129 T 06-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c LK06_RS08490 7ef2b900dc43cf61c194146d0c5963ec 336 Gene3D G3DSA:3.20.20.30 1 333 1.3E-62 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS08490 7ef2b900dc43cf61c194146d0c5963ec 336 Pfam PF00296 Luciferase-like monooxygenase 19 315 2.3E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS31195 ed4f2b596c63d48fba109886cbb76f27 502 Gene3D G3DSA:3.40.50.2000 277 453 9.6E-24 T 06-07-2017 LK06_RS31195 ed4f2b596c63d48fba109886cbb76f27 502 Pfam PF13692 Glycosyl transferases group 1 299 441 6.2E-29 T 06-07-2017 LK06_RS31195 ed4f2b596c63d48fba109886cbb76f27 502 SUPERFAMILY SSF53756 181 473 5.38E-66 T 06-07-2017 LK06_RS31195 ed4f2b596c63d48fba109886cbb76f27 502 SUPERFAMILY SSF53756 15 98 5.38E-66 T 06-07-2017 LK06_RS31195 ed4f2b596c63d48fba109886cbb76f27 502 Pfam PF11997 Domain of unknown function (DUF3492) 13 274 1.1E-63 T 06-07-2017 IPR022622 Domain of unknown function DUF3492 LK06_RS15570 18b1b4fbb45fb7e1e55691acebd57d75 518 SUPERFAMILY SSF81606 6 238 5.36E-67 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15570 18b1b4fbb45fb7e1e55691acebd57d75 518 SMART SM00332 4 237 6.3E-29 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15570 18b1b4fbb45fb7e1e55691acebd57d75 518 Pfam PF00481 Protein phosphatase 2C 24 231 1.0E-10 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15570 18b1b4fbb45fb7e1e55691acebd57d75 518 SMART SM00331 13 239 1.5E-42 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15570 18b1b4fbb45fb7e1e55691acebd57d75 518 Gene3D G3DSA:3.60.40.10 3 239 6.3E-75 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS22215 8ce9db9bc62a426b438bbfaf5545baea 314 SUPERFAMILY SSF55811 123 306 3.66E-50 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS22215 8ce9db9bc62a426b438bbfaf5545baea 314 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 43 137 1.1E-11 T 06-07-2017 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 LK06_RS22215 8ce9db9bc62a426b438bbfaf5545baea 314 Pfam PF00293 NUDIX domain 175 281 2.0E-20 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS22215 8ce9db9bc62a426b438bbfaf5545baea 314 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 139 170 2.2E-14 T 06-07-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 LK06_RS22215 8ce9db9bc62a426b438bbfaf5545baea 314 ProSitePatterns PS00893 Nudix box signature. 206 227 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS22215 8ce9db9bc62a426b438bbfaf5545baea 314 Gene3D G3DSA:3.90.79.10 137 305 2.2E-53 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS22450 ceb3c3b9138390d834ef23307c1d0882 261 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 17 246 6.6E-77 T 06-07-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 LK06_RS22450 ceb3c3b9138390d834ef23307c1d0882 261 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 227 1.6E-24 T 06-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 LK06_RS22450 ceb3c3b9138390d834ef23307c1d0882 261 Gene3D G3DSA:3.40.50.1360 2 253 2.0E-89 T 06-07-2017 LK06_RS22450 ceb3c3b9138390d834ef23307c1d0882 261 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 242 38.756 T 06-07-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 LK06_RS22450 ceb3c3b9138390d834ef23307c1d0882 261 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 06-07-2017 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 LK06_RS22450 ceb3c3b9138390d834ef23307c1d0882 261 SUPERFAMILY SSF100950 2 253 5.98E-87 T 06-07-2017 LK06_RS05450 d5c14094e499a9ef11aa8dd5fc702075 273 Gene3D G3DSA:3.90.550.10 31 195 3.3E-17 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS05450 d5c14094e499a9ef11aa8dd5fc702075 273 Pfam PF00535 Glycosyl transferase family 2 34 155 8.0E-21 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS05450 d5c14094e499a9ef11aa8dd5fc702075 273 SUPERFAMILY SSF53448 28 248 9.64E-40 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS18295 8ac9048186aba8621354900d745af4e7 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 06-07-2017 IPR019844 Cold-shock conserved site LK06_RS18295 8ac9048186aba8621354900d745af4e7 67 Gene3D G3DSA:2.40.50.140 1 65 1.5E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS18295 8ac9048186aba8621354900d745af4e7 67 PIRSF PIRSF002599 1 67 4.1E-26 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 LK06_RS18295 8ac9048186aba8621354900d745af4e7 67 SUPERFAMILY SSF50249 1 65 6.86E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS18295 8ac9048186aba8621354900d745af4e7 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 5.0E-31 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS18295 8ac9048186aba8621354900d745af4e7 67 SMART SM00357 3 66 1.1E-30 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 LK06_RS18295 8ac9048186aba8621354900d745af4e7 67 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-19 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS18295 8ac9048186aba8621354900d745af4e7 67 PRINTS PR00050 Cold shock protein signature 39 57 1.2E-19 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS18295 8ac9048186aba8621354900d745af4e7 67 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-19 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS02730 f1240a16cfe2521229d32bbe32ee30a4 346 Gene3D G3DSA:3.40.50.720 1 260 1.4E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02730 f1240a16cfe2521229d32bbe32ee30a4 346 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 226 1.8E-27 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS02730 f1240a16cfe2521229d32bbe32ee30a4 346 SUPERFAMILY SSF51735 1 267 1.07E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00095 4ef7f45f2070879c1fb24ec5c67156f2 383 Pfam PF13556 PucR C-terminal helix-turn-helix domain 319 376 1.3E-22 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS31465 66ce6056f773651e585945df2a9f55dc 416 Pfam PF00266 Aminotransferase class-V 101 317 1.3E-15 T 06-07-2017 IPR000192 Aminotransferase class V domain LK06_RS31465 66ce6056f773651e585945df2a9f55dc 416 Hamap MF_01970 Kynureninase [kynU]. 3 400 32.116 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 LK06_RS31465 66ce6056f773651e585945df2a9f55dc 416 Gene3D G3DSA:3.40.640.10 109 260 1.1E-17 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS31465 66ce6056f773651e585945df2a9f55dc 416 Gene3D G3DSA:3.90.1150.10 261 407 1.8E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS31465 66ce6056f773651e585945df2a9f55dc 416 SUPERFAMILY SSF53383 13 400 3.16E-72 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS31465 66ce6056f773651e585945df2a9f55dc 416 PIRSF PIRSF038800 6 407 7.2E-123 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 65 80 6.5E-25 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 150 176 6.5E-25 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 86 106 6.5E-25 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 186 208 6.5E-25 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 35 60 6.5E-25 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 108 128 6.5E-25 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 197 433 7.7E-16 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 Pfam PF00355 Rieske [2Fe-2S] domain 50 133 2.4E-21 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 Gene3D G3DSA:3.90.380.10 156 435 1.6E-42 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 Gene3D G3DSA:2.102.10.10 50 155 2.4E-24 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 SUPERFAMILY SSF50022 19 164 3.54E-47 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS26420 e17ac615fb7b9b290fff2a5b87de7b39 436 SUPERFAMILY SSF55961 167 435 1.88E-35 T 06-07-2017 LK06_RS19580 0c3c5f7e891fdab2162211cf9a89b114 158 Pfam PF00583 Acetyltransferase (GNAT) family 55 137 1.5E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS19580 0c3c5f7e891fdab2162211cf9a89b114 158 SUPERFAMILY SSF55729 9 147 1.19E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS19580 0c3c5f7e891fdab2162211cf9a89b114 158 Gene3D G3DSA:3.40.630.30 9 154 4.6E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS06305 8159e5a357d2a2abc52f64005963aa94 363 Pfam PF01979 Amidohydrolase family 171 362 9.4E-13 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS06305 8159e5a357d2a2abc52f64005963aa94 363 SUPERFAMILY SSF51556 52 326 1.18E-61 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS06305 8159e5a357d2a2abc52f64005963aa94 363 Gene3D G3DSA:2.30.40.10 325 362 1.2E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS06305 8159e5a357d2a2abc52f64005963aa94 363 Gene3D G3DSA:2.30.40.10 36 53 1.2E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS06305 8159e5a357d2a2abc52f64005963aa94 363 Gene3D G3DSA:3.20.20.140 54 324 4.0E-63 T 06-07-2017 LK06_RS07395 9fc4b65292de0807b5ca031b0f3dc7dd 506 Gene3D G3DSA:3.50.50.60 174 175 3.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07395 9fc4b65292de0807b5ca031b0f3dc7dd 506 Gene3D G3DSA:3.50.50.60 446 498 3.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07395 9fc4b65292de0807b5ca031b0f3dc7dd 506 Gene3D G3DSA:3.50.50.60 1 49 3.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07395 9fc4b65292de0807b5ca031b0f3dc7dd 506 Gene3D G3DSA:3.50.50.60 382 383 3.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07395 9fc4b65292de0807b5ca031b0f3dc7dd 506 Gene3D G3DSA:3.50.50.60 82 105 3.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07395 9fc4b65292de0807b5ca031b0f3dc7dd 506 Gene3D G3DSA:3.50.50.60 210 299 3.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07395 9fc4b65292de0807b5ca031b0f3dc7dd 506 SUPERFAMILY SSF51905 459 497 2.33E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07395 9fc4b65292de0807b5ca031b0f3dc7dd 506 SUPERFAMILY SSF51905 1 330 2.33E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07395 9fc4b65292de0807b5ca031b0f3dc7dd 506 Pfam PF01593 Flavin containing amine oxidoreductase 9 496 1.2E-16 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 LK06_RS02870 7619a6446429dba79f933683d0e0b4cd 465 Pfam PF00583 Acetyltransferase (GNAT) family 353 422 1.6E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS02870 7619a6446429dba79f933683d0e0b4cd 465 Gene3D G3DSA:3.40.630.30 288 422 1.3E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS02870 7619a6446429dba79f933683d0e0b4cd 465 SUPERFAMILY SSF55729 281 422 1.7E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS02870 7619a6446429dba79f933683d0e0b4cd 465 Gene3D G3DSA:3.30.70.260 99 136 3.2E-4 T 06-07-2017 LK06_RS16185 e5e2254b1ca74bdd53d56dd9b9853309 182 SUPERFAMILY SSF56399 7 177 6.33E-58 T 06-07-2017 LK06_RS16185 e5e2254b1ca74bdd53d56dd9b9853309 182 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 5 168 7.1E-39 T 06-07-2017 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 LK06_RS16185 e5e2254b1ca74bdd53d56dd9b9853309 182 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 5 176 33.067 T 06-07-2017 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 LK06_RS05010 9500f8e08c6bc8386ebf2b5972e32f04 249 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 230 2.3E-117 T 06-07-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 LK06_RS05010 9500f8e08c6bc8386ebf2b5972e32f04 249 SUPERFAMILY SSF56235 10 229 8.75E-45 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS05010 9500f8e08c6bc8386ebf2b5972e32f04 249 Gene3D G3DSA:3.60.20.10 3 238 1.2E-85 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS05010 9500f8e08c6bc8386ebf2b5972e32f04 249 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 234 49.388 T 06-07-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 LK06_RS05010 9500f8e08c6bc8386ebf2b5972e32f04 249 Pfam PF00227 Proteasome subunit 25 191 6.8E-29 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 LK06_RS19495 815318f35a1d7f696c075c9ec6227054 388 Gene3D G3DSA:1.10.260.40 7 62 1.6E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS19495 815318f35a1d7f696c075c9ec6227054 388 Pfam PF13560 Helix-turn-helix domain 7 65 3.4E-10 T 06-07-2017 LK06_RS19495 815318f35a1d7f696c075c9ec6227054 388 SUPERFAMILY SSF47413 7 66 4.56E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS19495 815318f35a1d7f696c075c9ec6227054 388 SUPERFAMILY SSF48452 234 344 2.37E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS19495 815318f35a1d7f696c075c9ec6227054 388 Gene3D G3DSA:1.25.40.10 176 340 9.3E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS19495 815318f35a1d7f696c075c9ec6227054 388 SMART SM00530 7 62 2.5E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 SUPERFAMILY SSF53901 3 278 2.41E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 Pfam PF00108 Thiolase, N-terminal domain 7 231 1.0E-44 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 Gene3D G3DSA:3.40.47.10 148 186 8.8E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 Gene3D G3DSA:3.40.47.10 288 403 8.8E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 PIRSF PIRSF000429 2 404 8.1E-112 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 ProSitePatterns PS00099 Thiolases active site. 385 398 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 402 1.2E-136 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 Pfam PF02803 Thiolase, C-terminal domain 282 403 3.7E-48 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 SUPERFAMILY SSF53901 282 403 4.93E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 Gene3D G3DSA:3.40.47.10 5 128 1.8E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28620 dbdfcd3e2fbe937d261317f3656c07e5 404 Gene3D G3DSA:3.40.47.10 187 287 1.8E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS27355 46ee86bbc6193a60627f0c515b35ee42 595 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 328 4.1E-33 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LK06_RS27355 46ee86bbc6193a60627f0c515b35ee42 595 SUPERFAMILY SSF52518 1 185 1.09E-48 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS27355 46ee86bbc6193a60627f0c515b35ee42 595 SUPERFAMILY SSF52467 157 360 1.93E-44 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS27355 46ee86bbc6193a60627f0c515b35ee42 595 SUPERFAMILY SSF52518 370 564 3.4E-51 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS27355 46ee86bbc6193a60627f0c515b35ee42 595 Gene3D G3DSA:3.40.50.1220 188 359 4.5E-45 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain LK06_RS27355 46ee86bbc6193a60627f0c515b35ee42 595 Gene3D G3DSA:3.40.50.970 361 572 3.8E-59 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS27355 46ee86bbc6193a60627f0c515b35ee42 595 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 591 0.0 T 06-07-2017 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 LK06_RS27355 46ee86bbc6193a60627f0c515b35ee42 595 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 3.3E-50 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LK06_RS27355 46ee86bbc6193a60627f0c515b35ee42 595 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 553 2.9E-34 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LK06_RS27355 46ee86bbc6193a60627f0c515b35ee42 595 Gene3D G3DSA:3.40.50.970 2 182 4.1E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS15645 9612fd691cdcfdd6fb29b493e3654961 290 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 105 126 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS15645 9612fd691cdcfdd6fb29b493e3654961 290 Pfam PF01066 CDP-alcohol phosphatidyltransferase 48 126 3.9E-11 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS15645 9612fd691cdcfdd6fb29b493e3654961 290 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 52 224 1.1E-32 T 06-07-2017 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 LK06_RS16150 8ef977e6ab581e69ccd603cbfe16cd0d 305 Pfam PF08282 haloacid dehalogenase-like hydrolase 36 297 2.0E-45 T 06-07-2017 IPR023214 HAD-like domain LK06_RS16150 8ef977e6ab581e69ccd603cbfe16cd0d 305 SUPERFAMILY SSF56784 32 301 1.85E-54 T 06-07-2017 IPR023214 HAD-like domain LK06_RS16150 8ef977e6ab581e69ccd603cbfe16cd0d 305 Gene3D G3DSA:3.40.50.1000 205 301 1.9E-44 T 06-07-2017 IPR023214 HAD-like domain LK06_RS16150 8ef977e6ab581e69ccd603cbfe16cd0d 305 Gene3D G3DSA:3.40.50.1000 28 103 1.9E-44 T 06-07-2017 IPR023214 HAD-like domain LK06_RS24645 a8d75db676a28f6032bedf4c1a58e2d2 476 SUPERFAMILY SSF51905 196 326 1.4E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS24645 a8d75db676a28f6032bedf4c1a58e2d2 476 SUPERFAMILY SSF51905 20 139 1.4E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS24645 a8d75db676a28f6032bedf4c1a58e2d2 476 Pfam PF01266 FAD dependent oxidoreductase 46 406 2.5E-46 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS24645 a8d75db676a28f6032bedf4c1a58e2d2 476 Gene3D G3DSA:3.50.50.60 191 272 4.4E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS24645 a8d75db676a28f6032bedf4c1a58e2d2 476 Gene3D G3DSA:3.50.50.60 374 425 4.4E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS24645 a8d75db676a28f6032bedf4c1a58e2d2 476 Gene3D G3DSA:3.50.50.60 34 136 4.4E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS14015 a3b903d6a5e1d846090ddb56b6454b08 144 Pfam PF13581 Histidine kinase-like ATPase domain 8 134 1.6E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 1.4E-16 T 06-07-2017 LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 PRINTS PR00419 Adrenodoxin reductase family signature 212 225 1.4E-16 T 06-07-2017 LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 1.4E-16 T 06-07-2017 LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 PRINTS PR00419 Adrenodoxin reductase family signature 145 159 1.4E-16 T 06-07-2017 LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 164 4.9E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 Gene3D G3DSA:3.50.50.60 96 315 2.6E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 SUPERFAMILY SSF51905 104 316 6.47E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 PIRSF PIRSF000362 1 445 3.5E-143 T 06-07-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 SUPERFAMILY SSF51971 3 167 1.77E-15 T 06-07-2017 LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 Gene3D G3DSA:3.40.50.720 2 95 1.2E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS29870 48a6dda3695f34d7f7087cbe6277a9e2 448 Gene3D G3DSA:3.40.50.720 316 439 1.2E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 407 1259 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 PIRSF PIRSF000157 12 1262 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 145 376 5.1E-50 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 24 60 2.8E-11 T 06-07-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1112 1260 3.9E-46 T 06-07-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 SUPERFAMILY SSF52518 444 851 1.25E-87 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 SUPERFAMILY SSF52777 132 376 9.78E-55 T 06-07-2017 LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 Gene3D G3DSA:3.40.50.970 919 1118 2.4E-23 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 Gene3D G3DSA:3.30.559.10 133 376 2.4E-51 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 Pfam PF02779 Transketolase, pyrimidine binding domain 913 1106 1.2E-56 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 Pfam PF00676 Dehydrogenase E1 component 529 852 4.4E-56 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 Gene3D G3DSA:3.40.50.970 486 854 6.0E-80 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 SMART SM00861 914 1107 6.6E-54 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS22655 61c6690981d18907bc4a138fbfb85002 1262 SUPERFAMILY SSF52518 904 1112 7.36E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS30680 24bcdf6a47ef50a04b4f2d8a959d5d20 285 Gene3D G3DSA:3.40.630.30 6 124 7.1E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS30680 24bcdf6a47ef50a04b4f2d8a959d5d20 285 SUPERFAMILY SSF55729 9 264 1.27E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS30680 24bcdf6a47ef50a04b4f2d8a959d5d20 285 Gene3D G3DSA:3.40.630.30 145 255 1.3E-5 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS26990 77b5af007b80aa938c77c7ae8d4083b7 545 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 181 276 5.4E-17 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS26990 77b5af007b80aa938c77c7ae8d4083b7 545 Gene3D G3DSA:1.20.140.10 274 444 1.7E-41 T 06-07-2017 LK06_RS26990 77b5af007b80aa938c77c7ae8d4083b7 545 Gene3D G3DSA:2.40.110.10 181 273 2.4E-21 T 06-07-2017 LK06_RS26990 77b5af007b80aa938c77c7ae8d4083b7 545 SUPERFAMILY SSF47203 291 442 1.01E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS26990 77b5af007b80aa938c77c7ae8d4083b7 545 SUPERFAMILY SSF56645 66 283 7.19E-34 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS26990 77b5af007b80aa938c77c7ae8d4083b7 545 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 398 417 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS26990 77b5af007b80aa938c77c7ae8d4083b7 545 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 439 2.3E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS10630 e73e0ad554caa0b638e56fdd77f4c4f4 278 Gene3D G3DSA:1.10.260.40 6 73 2.8E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10630 e73e0ad554caa0b638e56fdd77f4c4f4 278 SMART SM00530 17 72 1.2E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS10630 e73e0ad554caa0b638e56fdd77f4c4f4 278 SUPERFAMILY SSF47413 9 74 1.48E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10630 e73e0ad554caa0b638e56fdd77f4c4f4 278 Pfam PF13560 Helix-turn-helix domain 13 69 1.0E-12 T 06-07-2017 LK06_RS30240 2cc356ad0fd67c051dd5c6e0e56dcdd5 299 SUPERFAMILY SSF52402 162 297 5.27E-24 T 06-07-2017 LK06_RS30240 2cc356ad0fd67c051dd5c6e0e56dcdd5 299 Pfam PF00582 Universal stress protein family 1 136 7.6E-27 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS30240 2cc356ad0fd67c051dd5c6e0e56dcdd5 299 Pfam PF00582 Universal stress protein family 162 297 3.6E-16 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS30240 2cc356ad0fd67c051dd5c6e0e56dcdd5 299 Gene3D G3DSA:3.40.50.620 1 136 2.8E-31 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS30240 2cc356ad0fd67c051dd5c6e0e56dcdd5 299 Gene3D G3DSA:3.40.50.620 158 297 6.4E-26 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS30240 2cc356ad0fd67c051dd5c6e0e56dcdd5 299 PRINTS PR01438 Universal stress protein signature 2 20 4.9E-13 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS30240 2cc356ad0fd67c051dd5c6e0e56dcdd5 299 PRINTS PR01438 Universal stress protein signature 96 108 4.9E-13 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS30240 2cc356ad0fd67c051dd5c6e0e56dcdd5 299 PRINTS PR01438 Universal stress protein signature 114 136 4.9E-13 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS30240 2cc356ad0fd67c051dd5c6e0e56dcdd5 299 SUPERFAMILY SSF52402 3 137 1.84E-27 T 06-07-2017 LK06_RS03105 d1898f1d5935bd49bd5897fb8255afe7 155 SUPERFAMILY SSF54427 2 143 6.31E-25 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS03105 d1898f1d5935bd49bd5897fb8255afe7 155 Pfam PF13577 SnoaL-like domain 2 134 5.5E-21 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain LK06_RS03105 d1898f1d5935bd49bd5897fb8255afe7 155 Gene3D G3DSA:3.10.450.50 1 144 2.8E-39 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS27455 a32b7d6dfe401be13fbf38c9e7cd6bb1 420 SMART SM00327 39 229 3.8E-17 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS27455 a32b7d6dfe401be13fbf38c9e7cd6bb1 420 SUPERFAMILY SSF53300 40 226 7.7E-24 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS27455 a32b7d6dfe401be13fbf38c9e7cd6bb1 420 Pfam PF13519 von Willebrand factor type A domain 42 158 3.5E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS27455 a32b7d6dfe401be13fbf38c9e7cd6bb1 420 Gene3D G3DSA:3.40.50.410 42 226 2.3E-13 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS14575 ac6f2dc3612bac1e73d2428e08aecb89 275 Gene3D G3DSA:1.10.260.40 2 60 1.3E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS14575 ac6f2dc3612bac1e73d2428e08aecb89 275 Pfam PF13560 Helix-turn-helix domain 1 61 8.4E-11 T 06-07-2017 LK06_RS14575 ac6f2dc3612bac1e73d2428e08aecb89 275 SMART SM00530 5 60 3.6E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS14575 ac6f2dc3612bac1e73d2428e08aecb89 275 SUPERFAMILY SSF47413 2 60 4.02E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS11710 16b872fb9a377d4198adeaf2949ab381 188 SUPERFAMILY SSF52317 1 183 1.05E-49 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS11710 16b872fb9a377d4198adeaf2949ab381 188 Gene3D G3DSA:3.40.50.880 1 184 9.7E-53 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS11710 16b872fb9a377d4198adeaf2949ab381 188 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 181 2.6E-50 T 06-07-2017 IPR006286 Peptidase C56, PfpI LK06_RS11710 16b872fb9a377d4198adeaf2949ab381 188 Pfam PF01965 DJ-1/PfpI family 4 178 5.0E-49 T 06-07-2017 IPR002818 DJ-1/PfpI LK06_RS04105 6654ad4b838b54735b94aa32a62dc869 368 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 LK06_RS04105 6654ad4b838b54735b94aa32a62dc869 368 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 344 47.348 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04105 6654ad4b838b54735b94aa32a62dc869 368 Pfam PF01180 Dihydroorotate dehydrogenase 50 348 7.6E-94 T 06-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 LK06_RS04105 6654ad4b838b54735b94aa32a62dc869 368 SUPERFAMILY SSF51395 1 364 1.89E-102 T 06-07-2017 LK06_RS04105 6654ad4b838b54735b94aa32a62dc869 368 Gene3D G3DSA:3.20.20.70 1 365 2.7E-129 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS04105 6654ad4b838b54735b94aa32a62dc869 368 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 5 365 6.0E-129 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS19490 b661c9d03b9f5f280917cce66f920831 236 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 9 199 2.4E-22 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase LK06_RS19490 b661c9d03b9f5f280917cce66f920831 236 SUPERFAMILY SSF100950 6 211 7.25E-30 T 06-07-2017 LK06_RS19490 b661c9d03b9f5f280917cce66f920831 236 Gene3D G3DSA:3.40.50.10420 6 215 7.6E-28 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain LK06_RS02410 1e9e8e89ed83f5e72161b0f9e14d4eec 337 SMART SM00116 225 273 1.1 T 06-07-2017 IPR000644 CBS domain LK06_RS02410 1e9e8e89ed83f5e72161b0f9e14d4eec 337 SMART SM00116 285 333 1.7 T 06-07-2017 IPR000644 CBS domain LK06_RS02410 1e9e8e89ed83f5e72161b0f9e14d4eec 337 Pfam PF00571 CBS domain 284 333 9.1E-8 T 06-07-2017 IPR000644 CBS domain LK06_RS02410 1e9e8e89ed83f5e72161b0f9e14d4eec 337 Pfam PF00571 CBS domain 238 270 0.0041 T 06-07-2017 IPR000644 CBS domain LK06_RS02410 1e9e8e89ed83f5e72161b0f9e14d4eec 337 Pfam PF01595 Domain of unknown function DUF21 8 199 3.0E-40 T 06-07-2017 IPR002550 Domain of unknown function DUF21 LK06_RS02410 1e9e8e89ed83f5e72161b0f9e14d4eec 337 SUPERFAMILY SSF54631 205 334 1.07E-24 T 06-07-2017 LK06_RS02410 1e9e8e89ed83f5e72161b0f9e14d4eec 337 Gene3D G3DSA:3.10.580.10 225 332 2.6E-17 T 06-07-2017 LK06_RS32075 4e32d7a4004dce6b1d01f350fce616bb 120 SUPERFAMILY SSF55620 2 119 9.45E-34 T 06-07-2017 LK06_RS32075 4e32d7a4004dce6b1d01f350fce616bb 120 PIRSF PIRSF006113 1 120 2.5E-27 T 06-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 LK06_RS32075 4e32d7a4004dce6b1d01f350fce616bb 120 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 119 2.8E-31 T 06-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 LK06_RS32075 4e32d7a4004dce6b1d01f350fce616bb 120 Gene3D G3DSA:3.30.479.10 1 119 6.5E-34 T 06-07-2017 LK06_RS30805 5a7ea15d2945ca7fe8812b0812999f13 264 SUPERFAMILY SSF54593 138 249 1.17E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30805 5a7ea15d2945ca7fe8812b0812999f13 264 SUPERFAMILY SSF54593 10 121 7.79E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30805 5a7ea15d2945ca7fe8812b0812999f13 264 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 117 1.1E-4 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS30805 5a7ea15d2945ca7fe8812b0812999f13 264 Gene3D G3DSA:3.10.180.10 8 124 7.1E-34 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30805 5a7ea15d2945ca7fe8812b0812999f13 264 Gene3D G3DSA:3.10.180.10 138 250 9.2E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS26300 1c5756f2dbb8f0e4d1b187a34949489c 281 Gene3D G3DSA:3.40.50.150 20 258 1.9E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26300 1c5756f2dbb8f0e4d1b187a34949489c 281 SUPERFAMILY SSF53335 7 278 3.38E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26300 1c5756f2dbb8f0e4d1b187a34949489c 281 Pfam PF04072 Leucine carboxyl methyltransferase 9 184 5.8E-50 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 LK06_RS26300 1c5756f2dbb8f0e4d1b187a34949489c 281 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 7 261 1.1E-52 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 LK06_RS14835 5fdd75dedd5c1c1ad820a623d0537987 255 Gene3D G3DSA:3.40.33.10 128 250 1.7E-14 T 06-07-2017 IPR014044 CAP domain LK06_RS14835 5fdd75dedd5c1c1ad820a623d0537987 255 Pfam PF00188 Cysteine-rich secretory protein family 137 251 1.9E-21 T 06-07-2017 IPR014044 CAP domain LK06_RS14835 5fdd75dedd5c1c1ad820a623d0537987 255 SUPERFAMILY SSF55797 130 252 1.64E-24 T 06-07-2017 IPR014044 CAP domain LK06_RS20660 82ebb9b01551e52ca95cd42c0917ff31 394 Gene3D G3DSA:3.40.630.30 201 364 1.5E-46 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS20660 82ebb9b01551e52ca95cd42c0917ff31 394 SUPERFAMILY SSF55729 201 380 1.59E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS20660 82ebb9b01551e52ca95cd42c0917ff31 394 SUPERFAMILY SSF55729 161 208 9.53E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS20660 82ebb9b01551e52ca95cd42c0917ff31 394 SUPERFAMILY SSF55729 19 134 9.53E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS20660 82ebb9b01551e52ca95cd42c0917ff31 394 Pfam PF02388 FemAB family 39 266 4.3E-24 T 06-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 LK06_RS20660 82ebb9b01551e52ca95cd42c0917ff31 394 Pfam PF02388 FemAB family 286 375 3.1E-12 T 06-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 LK06_RS20660 82ebb9b01551e52ca95cd42c0917ff31 394 Gene3D G3DSA:3.40.630.30 19 200 1.7E-40 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS03010 6dd92d884d6e0ffe78a665620e47ff83 175 Gene3D G3DSA:2.160.10.10 12 172 3.1E-45 T 06-07-2017 LK06_RS03010 6dd92d884d6e0ffe78a665620e47ff83 175 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 93 125 5.7E-7 T 06-07-2017 IPR001451 Hexapeptide repeat LK06_RS03010 6dd92d884d6e0ffe78a665620e47ff83 175 SUPERFAMILY SSF51161 12 169 1.94E-45 T 06-07-2017 IPR011004 Trimeric LpxA-like LK06_RS26865 a6feae33b9928ba8685dcdfb42219032 118 Gene3D G3DSA:3.40.190.10 16 64 1.8E-7 T 06-07-2017 LK06_RS26865 a6feae33b9928ba8685dcdfb42219032 118 Pfam PF03466 LysR substrate binding domain 17 98 3.4E-9 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS26865 a6feae33b9928ba8685dcdfb42219032 118 SUPERFAMILY SSF53850 15 102 4.52E-10 T 06-07-2017 LK06_RS25725 3b8bd5a05ff8546a187882ee0ff3924a 170 SUPERFAMILY SSF55874 69 165 1.4E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS25725 3b8bd5a05ff8546a187882ee0ff3924a 170 Pfam PF13581 Histidine kinase-like ATPase domain 48 163 4.4E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22130 86ef3f226d13d2dc64e373965b81059f 75 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 3.6E-30 T 06-07-2017 IPR021456 Protein of unknown function DUF3107 LK06_RS13015 83b22103a51b6a518442196c50536b95 67 PIRSF PIRSF002599 1 67 5.9E-26 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 LK06_RS13015 83b22103a51b6a518442196c50536b95 67 SUPERFAMILY SSF50249 1 66 1.14E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS13015 83b22103a51b6a518442196c50536b95 67 SMART SM00357 3 67 1.8E-31 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 LK06_RS13015 83b22103a51b6a518442196c50536b95 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 5.3E-32 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS13015 83b22103a51b6a518442196c50536b95 67 Gene3D G3DSA:2.40.50.140 1 66 7.5E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS13015 83b22103a51b6a518442196c50536b95 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site LK06_RS13015 83b22103a51b6a518442196c50536b95 67 PRINTS PR00050 Cold shock protein signature 25 34 3.1E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS13015 83b22103a51b6a518442196c50536b95 67 PRINTS PR00050 Cold shock protein signature 4 19 3.1E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS13015 83b22103a51b6a518442196c50536b95 67 PRINTS PR00050 Cold shock protein signature 40 58 3.1E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS10045 c090b6a6f135c00a3e4c589e75b64ddd 479 Pfam PF01494 FAD binding domain 1 332 1.4E-80 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS10045 c090b6a6f135c00a3e4c589e75b64ddd 479 Gene3D G3DSA:3.50.50.60 255 338 2.6E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10045 c090b6a6f135c00a3e4c589e75b64ddd 479 Gene3D G3DSA:3.50.50.60 1 170 2.6E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10045 c090b6a6f135c00a3e4c589e75b64ddd 479 SUPERFAMILY SSF51905 1 165 7.11E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10045 c090b6a6f135c00a3e4c589e75b64ddd 479 SUPERFAMILY SSF51905 263 380 7.11E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10045 c090b6a6f135c00a3e4c589e75b64ddd 479 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 1.2E-33 T 06-07-2017 LK06_RS10045 c090b6a6f135c00a3e4c589e75b64ddd 479 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 1.2E-33 T 06-07-2017 LK06_RS10045 c090b6a6f135c00a3e4c589e75b64ddd 479 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 1.2E-33 T 06-07-2017 LK06_RS10045 c090b6a6f135c00a3e4c589e75b64ddd 479 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 298 1.2E-33 T 06-07-2017 LK06_RS10045 c090b6a6f135c00a3e4c589e75b64ddd 479 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 318 1.2E-33 T 06-07-2017 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 Gene3D G3DSA:1.10.630.10 10 410 8.4E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 355 364 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 Pfam PF00067 Cytochrome P450 53 276 9.2E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 Pfam PF00067 Cytochrome P450 288 384 3.8E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 SUPERFAMILY SSF48264 27 410 4.58E-83 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 PRINTS PR00359 B-class P450 signature 201 223 9.9E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 PRINTS PR00359 B-class P450 signature 302 329 9.9E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 PRINTS PR00359 B-class P450 signature 362 373 9.9E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 PRINTS PR00359 B-class P450 signature 90 101 9.9E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 PRINTS PR00359 B-class P450 signature 140 156 9.9E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 PRINTS PR00359 B-class P450 signature 353 362 9.9E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS26260 c4dea3945612f77b742082de6d2a6fa3 410 PRINTS PR00359 B-class P450 signature 285 296 9.9E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PIRSF PIRSF000350 1 471 2.4E-67 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 Gene3D G3DSA:3.50.50.60 155 335 3.6E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 1.5E-19 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 1.5E-19 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.5E-19 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 1.5E-19 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 1.5E-19 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 360 466 1.7E-22 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 Gene3D G3DSA:3.30.390.30 355 473 1.8E-27 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 SUPERFAMILY SSF55424 356 474 4.12E-27 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 437 1.6E-49 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 1.6E-49 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 464 1.6E-49 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 1.6E-49 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 1.6E-49 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 1.6E-49 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 1.6E-49 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 1.6E-49 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 356 377 1.6E-49 T 06-07-2017 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 Gene3D G3DSA:3.50.50.60 8 154 2.0E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 322 5.6E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 SUPERFAMILY SSF51905 9 110 2.02E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01475 95339b43d278c55ee07f0c8bbb224d8c 476 SUPERFAMILY SSF51905 141 340 2.02E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 PIRSF PIRSF000429 1 389 5.8E-113 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 ProSitePatterns PS00099 Thiolases active site. 370 383 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 SUPERFAMILY SSF53901 267 388 6.45E-40 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 Gene3D G3DSA:3.40.47.10 6 125 3.2E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 Gene3D G3DSA:3.40.47.10 185 272 3.2E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 Pfam PF02803 Thiolase, C-terminal domain 266 388 1.4E-42 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 Gene3D G3DSA:3.40.47.10 149 184 7.0E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 Gene3D G3DSA:3.40.47.10 273 388 7.0E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 Pfam PF00108 Thiolase, N-terminal domain 6 257 9.2E-52 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 387 5.2E-116 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS08615 8348cfcaa6f26fc6272028050bc15479 389 SUPERFAMILY SSF53901 5 266 1.98E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS05275 080d508f33b9fdda75f5f02a59f93eec 106 Pfam PF02656 Domain of unknown function (DUF202) 9 70 1.2E-10 T 06-07-2017 IPR003807 Domain of unknown function DUF202 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 29 251 4.1E-45 T 06-07-2017 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 PIRSF PIRSF005536 1 689 1.9E-178 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 PRINTS PR00743 Glycosyl hydrolase family 36 signature 434 449 2.6E-53 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 PRINTS PR00743 Glycosyl hydrolase family 36 signature 326 341 2.6E-53 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 PRINTS PR00743 Glycosyl hydrolase family 36 signature 210 225 2.6E-53 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 PRINTS PR00743 Glycosyl hydrolase family 36 signature 262 282 2.6E-53 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 PRINTS PR00743 Glycosyl hydrolase family 36 signature 486 502 2.6E-53 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 PRINTS PR00743 Glycosyl hydrolase family 36 signature 298 312 2.6E-53 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 PRINTS PR00743 Glycosyl hydrolase family 36 signature 511 527 2.6E-53 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 PRINTS PR00743 Glycosyl hydrolase family 36 signature 376 398 2.6E-53 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 SUPERFAMILY SSF51445 294 619 3.08E-94 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 622 688 8.9E-11 T 06-07-2017 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 Pfam PF02065 Melibiase 259 602 7.7E-117 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 LK06_RS28785 0490a9573d13e5cc783692d3fe0a815f 691 Gene3D G3DSA:3.20.20.70 294 584 4.2E-49 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS09890 f31cd0155f192e3ebf8f014258cc5880 504 Gene3D G3DSA:3.90.190.20 364 503 6.0E-38 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS09890 f31cd0155f192e3ebf8f014258cc5880 504 SUPERFAMILY SSF53244 364 502 1.47E-27 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS09890 f31cd0155f192e3ebf8f014258cc5880 504 TIGRFAM TIGR01499 folC: bifunctional protein FolC 86 498 2.7E-99 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 LK06_RS09890 f31cd0155f192e3ebf8f014258cc5880 504 Gene3D G3DSA:3.40.1190.10 81 362 4.5E-94 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS09890 f31cd0155f192e3ebf8f014258cc5880 504 Pfam PF08245 Mur ligase middle domain 107 334 2.9E-15 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS09890 f31cd0155f192e3ebf8f014258cc5880 504 Pfam PF02875 Mur ligase family, glutamate ligase domain 363 442 8.0E-13 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS09890 f31cd0155f192e3ebf8f014258cc5880 504 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 203 218 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 LK06_RS09890 f31cd0155f192e3ebf8f014258cc5880 504 SUPERFAMILY SSF53623 66 360 6.62E-88 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS13865 ea931f78e77c99d9ba0ff816b703162d 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 LK06_RS13865 ea931f78e77c99d9ba0ff816b703162d 486 Gene3D G3DSA:3.40.309.10 268 450 3.6E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS13865 ea931f78e77c99d9ba0ff816b703162d 486 Gene3D G3DSA:3.40.605.10 10 267 5.7E-77 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS13865 ea931f78e77c99d9ba0ff816b703162d 486 Pfam PF00171 Aldehyde dehydrogenase family 26 475 4.1E-153 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS13865 ea931f78e77c99d9ba0ff816b703162d 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 LK06_RS13865 ea931f78e77c99d9ba0ff816b703162d 486 SUPERFAMILY SSF53720 6 479 1.96E-150 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS21475 0b6efc9c275f6a5d036ea21f2f8746f8 237 Pfam PF08044 Domain of unknown function (DUF1707) 23 75 9.8E-21 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 LK06_RS21475 0b6efc9c275f6a5d036ea21f2f8746f8 237 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 124 182 1.5E-8 T 06-07-2017 IPR024425 Cell wall-active antibiotics response 4TMS YvqF LK06_RS31375 307ac0ce64f9a9f9f9e69becff885b3a 303 Gene3D G3DSA:3.40.50.720 1 240 5.5E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31375 307ac0ce64f9a9f9f9e69becff885b3a 303 SUPERFAMILY SSF51735 1 299 3.69E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31375 307ac0ce64f9a9f9f9e69becff885b3a 303 Pfam PF08338 Domain of unknown function (DUF1731) 252 297 4.3E-17 T 06-07-2017 IPR013549 Domain of unknown function DUF1731 LK06_RS31375 307ac0ce64f9a9f9f9e69becff885b3a 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 129 1.2E-13 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS31375 307ac0ce64f9a9f9f9e69becff885b3a 303 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 295 1.8E-92 T 06-07-2017 IPR010099 Epimerase family protein SDR39U1 LK06_RS31140 e230ff7f3462c9d603611a5d318c59a6 317 Gene3D G3DSA:3.40.190.10 179 264 4.4E-15 T 06-07-2017 LK06_RS31140 e230ff7f3462c9d603611a5d318c59a6 317 SUPERFAMILY SSF46785 3 100 2.78E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31140 e230ff7f3462c9d603611a5d318c59a6 317 Pfam PF03466 LysR substrate binding domain 92 292 2.0E-20 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS31140 e230ff7f3462c9d603611a5d318c59a6 317 Gene3D G3DSA:1.10.10.10 3 83 9.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS31140 e230ff7f3462c9d603611a5d318c59a6 317 Gene3D G3DSA:3.40.190.10 95 178 2.8E-9 T 06-07-2017 LK06_RS31140 e230ff7f3462c9d603611a5d318c59a6 317 SUPERFAMILY SSF53850 92 299 6.05E-19 T 06-07-2017 LK06_RS31140 e230ff7f3462c9d603611a5d318c59a6 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.0E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31140 e230ff7f3462c9d603611a5d318c59a6 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31140 e230ff7f3462c9d603611a5d318c59a6 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31140 e230ff7f3462c9d603611a5d318c59a6 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS31065 4e5ec9fe5082dfb0f7c6ee681eb008ca 200 Pfam PF01300 Telomere recombination 17 192 7.5E-43 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 LK06_RS31065 4e5ec9fe5082dfb0f7c6ee681eb008ca 200 Gene3D G3DSA:3.90.870.10 1 198 2.4E-60 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain LK06_RS31065 4e5ec9fe5082dfb0f7c6ee681eb008ca 200 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 1 195 1.3E-54 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 LK06_RS31065 4e5ec9fe5082dfb0f7c6ee681eb008ca 200 SUPERFAMILY SSF55821 1 198 8.24E-58 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain LK06_RS20475 3cdea6fa843b5380a0c146bf15aa6d0f 69 Pfam PF04149 Domain of unknown function (DUF397) 7 62 1.6E-20 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS20230 9f3d6866ceeb3ed5bc015ae70c8cdf03 155 SUPERFAMILY SSF50475 17 127 4.91E-16 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS20230 9f3d6866ceeb3ed5bc015ae70c8cdf03 155 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 27 102 2.7E-4 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS20230 9f3d6866ceeb3ed5bc015ae70c8cdf03 155 Gene3D G3DSA:2.30.110.10 18 128 8.9E-17 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS07930 6892120d1cf2a3dbeedd0ff1eb1c8298 156 Pfam PF06271 RDD family 43 150 2.8E-9 T 06-07-2017 IPR010432 RDD LK06_RS07930 6892120d1cf2a3dbeedd0ff1eb1c8298 156 PIRSF PIRSF021697 3 156 6.5E-58 T 06-07-2017 IPR016795 Uncharacterised conserved protein UCP021697, membrane LK06_RS12945 6d75f8c5ed6690653ed0fc1bd6c1ef80 262 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 93 250 28.972 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12945 6d75f8c5ed6690653ed0fc1bd6c1ef80 262 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 119 241 6.7E-47 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12945 6d75f8c5ed6690653ed0fc1bd6c1ef80 262 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 121 242 4.1E-42 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12945 6d75f8c5ed6690653ed0fc1bd6c1ef80 262 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 170 225 5.0E-24 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12945 6d75f8c5ed6690653ed0fc1bd6c1ef80 262 SUPERFAMILY SSF143243 106 258 3.53E-48 T 06-07-2017 LK06_RS26360 efefab521c90f744090c0249499f88f5 635 PRINTS PR00096 Glutamine amidotransferase superfamily signature 608 621 5.9E-8 T 06-07-2017 LK06_RS26360 efefab521c90f744090c0249499f88f5 635 PRINTS PR00096 Glutamine amidotransferase superfamily signature 489 498 5.9E-8 T 06-07-2017 LK06_RS26360 efefab521c90f744090c0249499f88f5 635 PRINTS PR00096 Glutamine amidotransferase superfamily signature 522 533 5.9E-8 T 06-07-2017 LK06_RS26360 efefab521c90f744090c0249499f88f5 635 PRINTS PR00097 Anthranilate synthase component II signature 522 533 2.2E-7 T 06-07-2017 LK06_RS26360 efefab521c90f744090c0249499f88f5 635 PRINTS PR00097 Anthranilate synthase component II signature 608 621 2.2E-7 T 06-07-2017 LK06_RS26360 efefab521c90f744090c0249499f88f5 635 PRINTS PR00097 Anthranilate synthase component II signature 448 462 2.2E-7 T 06-07-2017 LK06_RS26360 efefab521c90f744090c0249499f88f5 635 Gene3D G3DSA:3.60.120.10 94 396 3.6E-57 T 06-07-2017 IPR005801 ADC synthase GO:0009058 LK06_RS26360 efefab521c90f744090c0249499f88f5 635 SUPERFAMILY SSF52317 442 630 3.53E-25 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS26360 efefab521c90f744090c0249499f88f5 635 Pfam PF00425 chorismate binding enzyme 126 385 1.7E-44 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal LK06_RS26360 efefab521c90f744090c0249499f88f5 635 Pfam PF00117 Glutamine amidotransferase class-I 450 627 9.6E-22 T 06-07-2017 IPR017926 Glutamine amidotransferase LK06_RS26360 efefab521c90f744090c0249499f88f5 635 Gene3D G3DSA:3.40.50.880 447 627 8.7E-28 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS26360 efefab521c90f744090c0249499f88f5 635 SUPERFAMILY SSF56322 96 395 1.31E-64 T 06-07-2017 IPR005801 ADC synthase GO:0009058 LK06_RS24730 93230b7e33a5d842d695dafd962daa4f 166 SUPERFAMILY SSF55729 4 145 1.01E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS24730 93230b7e33a5d842d695dafd962daa4f 166 Pfam PF13302 Acetyltransferase (GNAT) domain 4 140 4.2E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS24730 93230b7e33a5d842d695dafd962daa4f 166 Gene3D G3DSA:3.40.630.30 3 146 3.5E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS10755 207056d7b8263537b5a64666973a6c08 179 Pfam PF13523 Acetyltransferase (GNAT) domain 14 157 1.4E-49 T 06-07-2017 LK06_RS10755 207056d7b8263537b5a64666973a6c08 179 SUPERFAMILY SSF55729 2 171 3.0E-45 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS10755 207056d7b8263537b5a64666973a6c08 179 Gene3D G3DSA:3.40.630.30 2 177 5.9E-58 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS10755 207056d7b8263537b5a64666973a6c08 179 SMART SM01006 11 58 1.9E-10 T 06-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain LK06_RS30840 148fc868512b5822986fa9f0ffbbdc8b 186 Gene3D G3DSA:1.10.357.10 64 184 7.9E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS30840 148fc868512b5822986fa9f0ffbbdc8b 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30840 148fc868512b5822986fa9f0ffbbdc8b 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30840 148fc868512b5822986fa9f0ffbbdc8b 186 SUPERFAMILY SSF48498 77 184 3.78E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS30840 148fc868512b5822986fa9f0ffbbdc8b 186 SUPERFAMILY SSF46689 3 63 1.65E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS30840 148fc868512b5822986fa9f0ffbbdc8b 186 Gene3D G3DSA:1.10.10.60 3 59 3.4E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS30840 148fc868512b5822986fa9f0ffbbdc8b 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 2.1E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS32120 39d485b7de060ef6736c196cd366ed63 301 Gene3D G3DSA:2.60.120.620 2 228 1.8E-55 T 06-07-2017 LK06_RS32120 39d485b7de060ef6736c196cd366ed63 301 SUPERFAMILY SSF51197 2 229 5.59E-58 T 06-07-2017 LK06_RS32120 39d485b7de060ef6736c196cd366ed63 301 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 10 211 2.7E-32 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase LK06_RS18490 e4a142e7098e77598cbf21925759edc6 197 Gene3D G3DSA:3.90.1570.10 22 157 9.9E-13 T 06-07-2017 IPR012296 Nuclease, putative, TT1808 LK06_RS18490 e4a142e7098e77598cbf21925759edc6 197 Pfam PF05685 Putative restriction endonuclease 28 160 1.3E-14 T 06-07-2017 IPR008538 Domain of unknown function DUF820 LK06_RS18490 e4a142e7098e77598cbf21925759edc6 197 SUPERFAMILY SSF52980 21 158 1.23E-11 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LK06_RS21180 dbb91e547224278d253bcbb03a891373 403 Gene3D G3DSA:3.40.640.10 51 278 5.0E-66 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS21180 dbb91e547224278d253bcbb03a891373 403 Pfam PF00155 Aminotransferase class I and II 34 392 9.8E-51 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS21180 dbb91e547224278d253bcbb03a891373 403 Gene3D G3DSA:3.90.1150.10 279 401 5.5E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS21180 dbb91e547224278d253bcbb03a891373 403 SUPERFAMILY SSF53383 6 399 1.48E-93 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS22705 b7338295f1e44389489f1f9e6e6fb5bb 971 SUPERFAMILY SSF55874 507 665 5.76E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22705 b7338295f1e44389489f1f9e6e6fb5bb 971 Pfam PF00672 HAMP domain 328 398 3.5E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS22705 b7338295f1e44389489f1f9e6e6fb5bb 971 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 554 665 4.0E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22705 b7338295f1e44389489f1f9e6e6fb5bb 971 Pfam PF08376 Nitrate and nitrite sensing 58 308 4.6E-34 T 06-07-2017 IPR013587 Nitrate/nitrite sensing protein LK06_RS22705 b7338295f1e44389489f1f9e6e6fb5bb 971 Gene3D G3DSA:3.30.565.10 516 667 1.2E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22705 b7338295f1e44389489f1f9e6e6fb5bb 971 SMART SM00387 551 667 4.0E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS05700 3d8e32ee573273b457722c97349302dc 377 Pfam PF13614 AAA domain 123 298 1.7E-61 T 06-07-2017 IPR025669 AAA domain LK06_RS05700 3d8e32ee573273b457722c97349302dc 377 SUPERFAMILY SSF52540 122 374 1.82E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05700 3d8e32ee573273b457722c97349302dc 377 Gene3D G3DSA:3.40.50.300 123 374 1.6E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15165 1f58e9b8207358314651c4e0c80c89e8 1636 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 1269 1344 6.2E-5 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS15165 1f58e9b8207358314651c4e0c80c89e8 1636 Gene3D G3DSA:3.40.50.300 1262 1398 1.2E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15165 1f58e9b8207358314651c4e0c80c89e8 1636 Pfam PF12458 ATPase involved in DNA repair 41 488 3.5E-169 T 06-07-2017 IPR020958 DUF3686 LK06_RS15165 1f58e9b8207358314651c4e0c80c89e8 1636 SUPERFAMILY SSF52540 1264 1414 6.11E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10795 49ca6e74a85d296b9e322b60be0238d2 200 SUPERFAMILY SSF53098 3 177 3.49E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS10795 49ca6e74a85d296b9e322b60be0238d2 200 Pfam PF00929 Exonuclease 6 168 9.4E-25 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III LK06_RS10795 49ca6e74a85d296b9e322b60be0238d2 200 Hamap MF_00045 Oligoribonuclease [orn]. 1 179 37.688 T 06-07-2017 IPR022894 Oligoribonuclease GO:0016788 LK06_RS10795 49ca6e74a85d296b9e322b60be0238d2 200 SMART SM00479 4 178 6.2E-27 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III LK06_RS10795 49ca6e74a85d296b9e322b60be0238d2 200 Gene3D G3DSA:3.30.420.10 1 177 3.9E-67 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 257 3.3E-58 T 06-07-2017 LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.6E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 Gene3D G3DSA:3.40.50.720 10 258 4.1E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 SUPERFAMILY SSF51735 14 258 4.4E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 4.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 4.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 4.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS20040 ca08d0a35af8437963f6a7f2f29a58e6 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS01630 b94f3141b6fcfe75d37bbaaaff99a118 223 Pfam PF04203 Sortase family 80 220 2.0E-16 T 06-07-2017 IPR005754 Sortase family LK06_RS01630 b94f3141b6fcfe75d37bbaaaff99a118 223 Gene3D G3DSA:2.40.260.10 79 219 3.2E-6 T 06-07-2017 IPR023365 Sortase domain LK06_RS01630 b94f3141b6fcfe75d37bbaaaff99a118 223 SUPERFAMILY SSF63817 71 221 1.59E-15 T 06-07-2017 IPR023365 Sortase domain LK06_RS00980 dd52846c30984117d7169b9639a089b2 220 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 6 146 3.5E-16 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G LK06_RS00980 dd52846c30984117d7169b9639a089b2 220 SUPERFAMILY SSF55961 1 146 7.83E-35 T 06-07-2017 LK06_RS00980 dd52846c30984117d7169b9639a089b2 220 Gene3D G3DSA:3.30.530.20 1 150 3.8E-38 T 06-07-2017 IPR023393 START-like domain LK06_RS31610 9c25976518c98773976228187c546006 497 SUPERFAMILY SSF53067 252 464 8.42E-25 T 06-07-2017 LK06_RS31610 9c25976518c98773976228187c546006 497 Gene3D G3DSA:3.30.420.40 250 465 1.3E-19 T 06-07-2017 LK06_RS31610 9c25976518c98773976228187c546006 497 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 10 247 4.7E-31 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 LK06_RS31610 9c25976518c98773976228187c546006 497 PIRSF PIRSF000538 8 483 1.9E-64 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LK06_RS31610 9c25976518c98773976228187c546006 497 SUPERFAMILY SSF53067 11 250 1.1E-44 T 06-07-2017 LK06_RS31610 9c25976518c98773976228187c546006 497 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 434 1.2E-15 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 LK06_RS31610 9c25976518c98773976228187c546006 497 Gene3D G3DSA:3.30.420.40 10 245 3.2E-41 T 06-07-2017 LK06_RS02775 566523c52b876f4e46727feb07af865d 223 SUPERFAMILY SSF53335 7 220 1.39E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS02775 566523c52b876f4e46727feb07af865d 223 Gene3D G3DSA:3.40.50.150 7 220 1.9E-74 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS02775 566523c52b876f4e46727feb07af865d 223 Pfam PF01596 O-methyltransferase 21 219 6.4E-64 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 LK06_RS04960 05b08bf80de7ee9c9aba121e989e6f96 94 Pfam PF02416 mttA/Hcf106 family 8 55 1.2E-15 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 LK06_RS04960 05b08bf80de7ee9c9aba121e989e6f96 94 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 6 50 1.9E-16 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 LK06_RS04960 05b08bf80de7ee9c9aba121e989e6f96 94 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 82 18.018 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 LK06_RS29990 9ca5f9269863ce59fe66d1c6125fbd0b 451 Pfam PF07687 Peptidase dimerisation domain 203 347 5.3E-13 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS29990 9ca5f9269863ce59fe66d1c6125fbd0b 451 SUPERFAMILY SSF53187 6 199 6.29E-53 T 06-07-2017 LK06_RS29990 9ca5f9269863ce59fe66d1c6125fbd0b 451 SUPERFAMILY SSF53187 361 449 6.29E-53 T 06-07-2017 LK06_RS29990 9ca5f9269863ce59fe66d1c6125fbd0b 451 Gene3D G3DSA:3.40.630.10 6 193 1.3E-58 T 06-07-2017 LK06_RS29990 9ca5f9269863ce59fe66d1c6125fbd0b 451 Gene3D G3DSA:3.40.630.10 360 449 1.3E-58 T 06-07-2017 LK06_RS29990 9ca5f9269863ce59fe66d1c6125fbd0b 451 Gene3D G3DSA:3.30.70.360 199 356 2.5E-35 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS29990 9ca5f9269863ce59fe66d1c6125fbd0b 451 Pfam PF01546 Peptidase family M20/M25/M40 86 439 3.5E-34 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 LK06_RS18890 d57898895eaa08b8698c8baec38c49dd 394 SUPERFAMILY SSF56645 1 236 7.33E-30 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS18890 d57898895eaa08b8698c8baec38c49dd 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 254 382 4.5E-20 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS18890 d57898895eaa08b8698c8baec38c49dd 394 Gene3D G3DSA:1.20.140.10 254 374 8.3E-27 T 06-07-2017 LK06_RS18890 d57898895eaa08b8698c8baec38c49dd 394 SUPERFAMILY SSF47203 254 381 4.67E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS18890 d57898895eaa08b8698c8baec38c49dd 394 Gene3D G3DSA:1.10.540.10 1 119 5.1E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18890 d57898895eaa08b8698c8baec38c49dd 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 6.2E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18890 d57898895eaa08b8698c8baec38c49dd 394 Gene3D G3DSA:2.40.110.10 134 237 4.5E-7 T 06-07-2017 LK06_RS00270 3cf96beeb47530f5d78331edc8cafa92 330 SUPERFAMILY SSF55469 116 181 4.94E-8 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS00270 3cf96beeb47530f5d78331edc8cafa92 330 SUPERFAMILY SSF55469 231 323 4.94E-8 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS00270 3cf96beeb47530f5d78331edc8cafa92 330 Gene3D G3DSA:3.40.109.30 5 92 7.0E-11 T 06-07-2017 LK06_RS00270 3cf96beeb47530f5d78331edc8cafa92 330 SUPERFAMILY SSF55469 6 105 2.88E-8 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS00270 3cf96beeb47530f5d78331edc8cafa92 330 Gene3D G3DSA:3.40.109.10 235 327 4.0E-15 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS00270 3cf96beeb47530f5d78331edc8cafa92 330 Gene3D G3DSA:3.40.109.10 114 184 4.0E-15 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS00865 55b8c56427fbbeb2ffdda07627d602a0 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 141 1.9E-5 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS00865 55b8c56427fbbeb2ffdda07627d602a0 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 1.9E-5 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS00865 55b8c56427fbbeb2ffdda07627d602a0 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 177 1.9E-5 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS00865 55b8c56427fbbeb2ffdda07627d602a0 246 SUPERFAMILY SSF56784 10 242 1.33E-36 T 06-07-2017 IPR023214 HAD-like domain LK06_RS00865 55b8c56427fbbeb2ffdda07627d602a0 246 Gene3D G3DSA:3.40.50.1000 7 24 1.6E-32 T 06-07-2017 IPR023214 HAD-like domain LK06_RS00865 55b8c56427fbbeb2ffdda07627d602a0 246 Gene3D G3DSA:3.40.50.1000 119 242 1.6E-32 T 06-07-2017 IPR023214 HAD-like domain LK06_RS00865 55b8c56427fbbeb2ffdda07627d602a0 246 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 104 216 2.7E-13 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS00865 55b8c56427fbbeb2ffdda07627d602a0 246 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 212 1.5E-11 T 06-07-2017 IPR023214 HAD-like domain LK06_RS00865 55b8c56427fbbeb2ffdda07627d602a0 246 Gene3D G3DSA:1.10.150.240 25 111 1.3E-4 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 LK06_RS00865 55b8c56427fbbeb2ffdda07627d602a0 246 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 10 213 4.6E-46 T 06-07-2017 IPR010976 Beta-phosphoglucomutase hydrolase LK06_RS29590 bfa893244151324b63528155e93ed185 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 559 3.0E-151 T 06-07-2017 IPR004613 Ribonuclease J GO:0003723|GO:0046872 LK06_RS29590 bfa893244151324b63528155e93ed185 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 40.04 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 LK06_RS29590 bfa893244151324b63528155e93ed185 561 Gene3D G3DSA:3.60.15.10 18 265 9.9E-75 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS29590 bfa893244151324b63528155e93ed185 561 SMART SM00849 31 225 1.3E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS29590 bfa893244151324b63528155e93ed185 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 1.9E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS29590 bfa893244151324b63528155e93ed185 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 413 5.3E-9 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain LK06_RS29590 bfa893244151324b63528155e93ed185 561 SUPERFAMILY SSF56281 19 433 1.27E-95 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS29590 bfa893244151324b63528155e93ed185 561 PIRSF PIRSF004803 14 561 8.4E-204 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 LK06_RS17490 394cb0899dfe91f4531b66564adac9fb 539 Pfam PF01565 FAD binding domain 110 242 3.5E-29 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LK06_RS17490 394cb0899dfe91f4531b66564adac9fb 539 Pfam PF08031 Berberine and berberine like 496 538 5.0E-12 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 LK06_RS17490 394cb0899dfe91f4531b66564adac9fb 539 SUPERFAMILY SSF56176 84 275 3.55E-49 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS17490 394cb0899dfe91f4531b66564adac9fb 539 Gene3D G3DSA:3.30.43.10 109 165 7.1E-8 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS17490 394cb0899dfe91f4531b66564adac9fb 539 Gene3D G3DSA:3.30.465.10 168 276 7.0E-11 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS08870 c4d855e361d6fb45fed1b3e82bfebd1e 164 Pfam PF11343 Protein of unknown function (DUF3145) 6 162 2.0E-73 T 06-07-2017 IPR021491 Protein of unknown function DUF3145 LK06_RS11465 7d22df4a9185ae1a5c039085a3217373 793 PIRSF PIRSF017245 1 793 0.0 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 LK06_RS11465 7d22df4a9185ae1a5c039085a3217373 793 Gene3D G3DSA:3.40.50.970 58 259 1.8E-19 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS11465 7d22df4a9185ae1a5c039085a3217373 793 Pfam PF09364 XFP N-terminal domain 12 388 1.1E-177 T 06-07-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal LK06_RS11465 7d22df4a9185ae1a5c039085a3217373 793 SUPERFAMILY SSF52518 6 373 2.72E-69 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS11465 7d22df4a9185ae1a5c039085a3217373 793 ProSitePatterns PS60002 Phosphoketolase signature 1. 148 154 - T 06-07-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 LK06_RS11465 7d22df4a9185ae1a5c039085a3217373 793 SUPERFAMILY SSF52518 380 592 1.53E-22 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS11465 7d22df4a9185ae1a5c039085a3217373 793 Hamap MF_01403 Probable phosphoketolase. 9 793 40.854 T 06-07-2017 IPR023962 Probable phosphoketolase LK06_RS11465 7d22df4a9185ae1a5c039085a3217373 793 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 403 579 1.5E-86 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 LK06_RS11465 7d22df4a9185ae1a5c039085a3217373 793 ProSitePatterns PS60003 Phosphoketolase signature 2. 161 179 - T 06-07-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 LK06_RS11465 7d22df4a9185ae1a5c039085a3217373 793 Pfam PF09363 XFP C-terminal domain 590 791 7.0E-89 T 06-07-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 LK06_RS09380 d504351528bea4bc4524bc7dc01a7e55 355 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 73 181 2.2E-27 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS09380 d504351528bea4bc4524bc7dc01a7e55 355 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 184 352 1.7E-53 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 LK06_RS09380 d504351528bea4bc4524bc7dc01a7e55 355 Gene3D G3DSA:1.10.390.10 186 352 5.1E-54 T 06-07-2017 LK06_RS09380 d504351528bea4bc4524bc7dc01a7e55 355 Gene3D G3DSA:3.10.170.10 67 185 7.0E-43 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 LK06_RS09380 d504351528bea4bc4524bc7dc01a7e55 355 SUPERFAMILY SSF55486 69 352 4.03E-81 T 06-07-2017 LK06_RS09380 d504351528bea4bc4524bc7dc01a7e55 355 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 172 188 8.2E-29 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS09380 d504351528bea4bc4524bc7dc01a7e55 355 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 274 290 8.2E-29 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS09380 d504351528bea4bc4524bc7dc01a7e55 355 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 136 156 8.2E-29 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS09380 d504351528bea4bc4524bc7dc01a7e55 355 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 193 204 8.2E-29 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LK06_RS04140 ab33b289136874045abbd1fc7cf6e2f6 167 Pfam PF01381 Helix-turn-helix 13 69 1.3E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS04140 ab33b289136874045abbd1fc7cf6e2f6 167 SUPERFAMILY SSF47413 4 74 4.74E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS04140 ab33b289136874045abbd1fc7cf6e2f6 167 Gene3D G3DSA:1.10.260.40 3 75 4.7E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS04140 ab33b289136874045abbd1fc7cf6e2f6 167 SMART SM00530 12 69 2.1E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS08750 08c84e5bed6891f0d5230ddb51a09ac9 845 Pfam PF15608 PELOTA RNA binding domain 749 828 9.3E-34 T 06-07-2017 IPR028157 PELOTA RNA-binding domain LK06_RS08750 08c84e5bed6891f0d5230ddb51a09ac9 845 Pfam PF12500 TRSP domain C terminus to PRTase_2 268 403 3.1E-46 T 06-07-2017 IPR022537 TRSP domain LK06_RS08750 08c84e5bed6891f0d5230ddb51a09ac9 845 Gene3D G3DSA:3.40.50.2020 76 190 1.5E-4 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS08750 08c84e5bed6891f0d5230ddb51a09ac9 845 SUPERFAMILY SSF53271 32 192 3.98E-7 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS08750 08c84e5bed6891f0d5230ddb51a09ac9 845 Pfam PF15609 Phosphoribosyl transferase 32 219 9.5E-68 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS08750 08c84e5bed6891f0d5230ddb51a09ac9 845 Pfam PF11202 Phosphoribosyl transferase (PRTase) 472 722 1.3E-106 T 06-07-2017 IPR011215 Phosphoribosyl transferase LK06_RS25045 2e19d42a4df4854567768b8486b355f7 286 Pfam PF02631 RecX family 149 269 6.1E-28 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 LK06_RS25045 2e19d42a4df4854567768b8486b355f7 286 Gene3D G3DSA:1.10.10.10 173 217 8.1E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25045 2e19d42a4df4854567768b8486b355f7 286 Gene3D G3DSA:1.10.10.10 126 171 6.1E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25045 2e19d42a4df4854567768b8486b355f7 286 Hamap MF_01114 Regulatory protein RecX [recX]. 121 274 15.454 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 LK06_RS02860 29d4ecbefea7f90340522ceb378ecbfd 276 Gene3D G3DSA:3.40.50.1820 17 273 1.2E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02860 29d4ecbefea7f90340522ceb378ecbfd 276 Pfam PF12697 Alpha/beta hydrolase family 31 269 1.4E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS02860 29d4ecbefea7f90340522ceb378ecbfd 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 3.6E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS02860 29d4ecbefea7f90340522ceb378ecbfd 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 3.6E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS02860 29d4ecbefea7f90340522ceb378ecbfd 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 3.6E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS02860 29d4ecbefea7f90340522ceb378ecbfd 276 SUPERFAMILY SSF53474 16 273 1.77E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS05795 2f448d26798da201ea54eda2fa78b57b 342 Gene3D G3DSA:3.40.50.10410 93 198 2.1E-27 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain LK06_RS05795 2f448d26798da201ea54eda2fa78b57b 342 Pfam PF13344 Haloacid dehalogenase-like hydrolase 24 123 4.6E-22 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA LK06_RS05795 2f448d26798da201ea54eda2fa78b57b 342 Gene3D G3DSA:3.40.50.1000 199 274 8.1E-30 T 06-07-2017 IPR023214 HAD-like domain LK06_RS05795 2f448d26798da201ea54eda2fa78b57b 342 Gene3D G3DSA:3.40.50.1000 18 92 8.1E-30 T 06-07-2017 IPR023214 HAD-like domain LK06_RS05795 2f448d26798da201ea54eda2fa78b57b 342 Pfam PF13242 HAD-hyrolase-like 200 271 5.1E-15 T 06-07-2017 LK06_RS05795 2f448d26798da201ea54eda2fa78b57b 342 SUPERFAMILY SSF56784 20 273 6.24E-51 T 06-07-2017 IPR023214 HAD-like domain LK06_RS07095 a1f5b717d2fbd883bcb762bd2039f55e 212 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 22 211 3.8E-57 T 06-07-2017 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein LK06_RS07095 a1f5b717d2fbd883bcb762bd2039f55e 212 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 30 210 7.0E-51 T 06-07-2017 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp LK06_RS05265 70d62394fe20113990a82f5c799ed995 171 SUPERFAMILY SSF55811 6 167 2.17E-31 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS05265 70d62394fe20113990a82f5c799ed995 171 ProSitePatterns PS00893 Nudix box signature. 69 90 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS05265 70d62394fe20113990a82f5c799ed995 171 PIRSF PIRSF017340 1 170 3.3E-75 T 06-07-2017 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 LK06_RS05265 70d62394fe20113990a82f5c799ed995 171 Gene3D G3DSA:3.90.79.10 1 168 4.1E-51 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS05265 70d62394fe20113990a82f5c799ed995 171 Pfam PF00293 NUDIX domain 32 144 9.4E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS18610 5919a0ba4f73acdc4c7e8aad5aeaf6a2 973 Pfam PF02913 FAD linked oxidases, C-terminal domain 251 497 1.2E-48 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LK06_RS18610 5919a0ba4f73acdc4c7e8aad5aeaf6a2 973 Gene3D G3DSA:1.10.1060.10 476 628 2.2E-12 T 06-07-2017 LK06_RS18610 5919a0ba4f73acdc4c7e8aad5aeaf6a2 973 Pfam PF13183 4Fe-4S dicluster domain 535 615 1.5E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LK06_RS18610 5919a0ba4f73acdc4c7e8aad5aeaf6a2 973 Gene3D G3DSA:3.30.465.10 95 251 2.9E-34 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS18610 5919a0ba4f73acdc4c7e8aad5aeaf6a2 973 SUPERFAMILY SSF56176 6 251 2.2E-58 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS18610 5919a0ba4f73acdc4c7e8aad5aeaf6a2 973 Pfam PF01565 FAD binding domain 40 177 4.9E-41 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LK06_RS18610 5919a0ba4f73acdc4c7e8aad5aeaf6a2 973 SUPERFAMILY SSF46548 536 620 6.28E-8 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 LK06_RS18610 5919a0ba4f73acdc4c7e8aad5aeaf6a2 973 SUPERFAMILY SSF55103 228 500 5.4E-52 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LK06_RS18610 5919a0ba4f73acdc4c7e8aad5aeaf6a2 973 Gene3D G3DSA:3.30.43.10 9 93 9.4E-20 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS13065 22db37b506e53c156e2ca8e12c081898 300 Pfam PF01040 UbiA prenyltransferase family 35 275 1.6E-52 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 LK06_RS13065 22db37b506e53c156e2ca8e12c081898 300 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 15 295 4.7E-89 T 06-07-2017 IPR006371 4-hydroxybenzoate polyprenyltransferase-related LK06_RS25535 90d824257ec6aa3dadc82b41ea1fd2fd 1097 SUPERFAMILY SSF52540 408 471 5.25E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25535 90d824257ec6aa3dadc82b41ea1fd2fd 1097 SUPERFAMILY SSF52540 250 336 5.25E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24195 5242e6f1c2b3b1a029fe5c7961f2e379 223 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 4.8E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 LK06_RS24195 5242e6f1c2b3b1a029fe5c7961f2e379 223 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 4.8E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 LK06_RS24195 5242e6f1c2b3b1a029fe5c7961f2e379 223 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 4.8E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 LK06_RS24195 5242e6f1c2b3b1a029fe5c7961f2e379 223 Pfam PF00216 Bacterial DNA-binding protein 1 88 6.2E-23 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 LK06_RS24195 5242e6f1c2b3b1a029fe5c7961f2e379 223 SMART SM00411 1 89 6.0E-37 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 LK06_RS24195 5242e6f1c2b3b1a029fe5c7961f2e379 223 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 LK06_RS24195 5242e6f1c2b3b1a029fe5c7961f2e379 223 SUPERFAMILY SSF47729 1 92 3.39E-24 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 LK06_RS24195 5242e6f1c2b3b1a029fe5c7961f2e379 223 Gene3D G3DSA:4.10.520.10 1 89 7.9E-27 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 LK06_RS11415 5032f8436c01f85f852dc45cb567b0c8 91 Pfam PF11238 Protein of unknown function (DUF3039) 26 81 1.1E-32 T 06-07-2017 IPR021400 Protein of unknown function DUF3039 LK06_RS01150 c01497654483769744e54241e861a8d6 391 Pfam PF14512 Putative TM nitroreductase 108 307 2.0E-11 T 06-07-2017 IPR029478 Putative nitroreductase TM1586 LK06_RS01150 c01497654483769744e54241e861a8d6 391 SUPERFAMILY SSF55469 107 248 1.11E-15 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS01150 c01497654483769744e54241e861a8d6 391 Gene3D G3DSA:3.40.109.10 107 242 7.9E-16 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS01720 63fee88b0140bcdca91dd5285f8f3e7d 298 SUPERFAMILY SSF161098 59 288 6.8E-56 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS01720 63fee88b0140bcdca91dd5285f8f3e7d 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 295 5.4E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS01720 63fee88b0140bcdca91dd5285f8f3e7d 298 Gene3D G3DSA:1.10.3720.10 65 296 1.1E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS01840 078a184132b2a7af4ef3ab0a3701d26c 179 SUPERFAMILY SSF55811 25 161 9.07E-12 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS01840 078a184132b2a7af4ef3ab0a3701d26c 179 Pfam PF00293 NUDIX domain 52 165 1.3E-6 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS01840 078a184132b2a7af4ef3ab0a3701d26c 179 Pfam PF16262 Domain of unknown function (DUF4916) 21 171 8.6E-23 T 06-07-2017 IPR032582 Protein of unknown function DUF4916 LK06_RS01840 078a184132b2a7af4ef3ab0a3701d26c 179 Gene3D G3DSA:3.90.79.10 28 160 1.8E-13 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS29910 1d758792c84f3761a1d7bfa98001b9c0 179 Pfam PF13673 Acetyltransferase (GNAT) domain 51 151 3.2E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS29910 1d758792c84f3761a1d7bfa98001b9c0 179 SUPERFAMILY SSF55729 7 159 1.13E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS29910 1d758792c84f3761a1d7bfa98001b9c0 179 Gene3D G3DSA:3.40.630.30 7 159 5.2E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS02180 9a1e080de339b11df82e395bbda975f7 323 Gene3D G3DSA:3.40.50.720 139 254 1.4E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02180 9a1e080de339b11df82e395bbda975f7 323 Gene3D G3DSA:3.90.180.10 1 138 4.7E-38 T 06-07-2017 IPR011032 GroES-like LK06_RS02180 9a1e080de339b11df82e395bbda975f7 323 SUPERFAMILY SSF50129 1 133 9.59E-33 T 06-07-2017 IPR011032 GroES-like LK06_RS02180 9a1e080de339b11df82e395bbda975f7 323 SUPERFAMILY SSF51735 105 260 3.71E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02180 9a1e080de339b11df82e395bbda975f7 323 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 133 154 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 LK06_RS02180 9a1e080de339b11df82e395bbda975f7 323 Pfam PF00107 Zinc-binding dehydrogenase 144 271 4.6E-31 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS02180 9a1e080de339b11df82e395bbda975f7 323 SMART SM00829 11 315 2.8E-31 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LK06_RS29125 54bb7a6c93b0264c942070bff51a4e3f 121 Gene3D G3DSA:2.80.10.50 2 107 6.8E-13 T 06-07-2017 LK06_RS29125 54bb7a6c93b0264c942070bff51a4e3f 121 Pfam PF00652 Ricin-type beta-trefoil lectin domain 2 118 5.3E-12 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS29125 54bb7a6c93b0264c942070bff51a4e3f 121 SUPERFAMILY SSF50370 5 103 7.8E-14 T 06-07-2017 IPR000772 Ricin B, lectin domain LK06_RS20005 c28e7a182c52bdbca8f5fa2a30dd6e78 278 Pfam PF12811 Bax inhibitor 1 like 39 275 2.6E-71 T 06-07-2017 IPR010539 Protein of unknown function UCP009160 LK06_RS20005 c28e7a182c52bdbca8f5fa2a30dd6e78 278 PIRSF PIRSF009160 1 278 1.4E-85 T 06-07-2017 IPR010539 Protein of unknown function UCP009160 LK06_RS11565 2f4b5060ec7a966c64e6b88cfbfa83b0 159 Gene3D G3DSA:2.40.280.10 8 128 4.0E-53 T 06-07-2017 IPR023620 Small protein B LK06_RS11565 2f4b5060ec7a966c64e6b88cfbfa83b0 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 159 73.81 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 LK06_RS11565 2f4b5060ec7a966c64e6b88cfbfa83b0 159 SUPERFAMILY SSF74982 3 133 7.98E-54 T 06-07-2017 IPR023620 Small protein B LK06_RS11565 2f4b5060ec7a966c64e6b88cfbfa83b0 159 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 06-07-2017 IPR020081 SsrA-binding protein, conserved site LK06_RS11565 2f4b5060ec7a966c64e6b88cfbfa83b0 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 7.0E-65 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 LK06_RS11565 2f4b5060ec7a966c64e6b88cfbfa83b0 159 Pfam PF01668 SmpB protein 9 72 3.6E-30 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 LK06_RS11565 2f4b5060ec7a966c64e6b88cfbfa83b0 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 150 5.0E-58 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 LK06_RS21345 6a9a7ed9ff339e0d983a10d7d6065a09 441 Gene3D G3DSA:3.40.50.1010 14 72 2.0E-9 T 06-07-2017 IPR029060 PIN domain-like LK06_RS21345 6a9a7ed9ff339e0d983a10d7d6065a09 441 Gene3D G3DSA:3.40.50.1010 105 153 2.0E-9 T 06-07-2017 IPR029060 PIN domain-like LK06_RS21345 6a9a7ed9ff339e0d983a10d7d6065a09 441 Pfam PF02562 PhoH-like protein 231 435 2.5E-54 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 LK06_RS21345 6a9a7ed9ff339e0d983a10d7d6065a09 441 Pfam PF13638 PIN domain 15 153 1.8E-25 T 06-07-2017 IPR002716 PIN domain LK06_RS21345 6a9a7ed9ff339e0d983a10d7d6065a09 441 SMART SM00670 13 140 4.4E-15 T 06-07-2017 IPR002716 PIN domain LK06_RS21345 6a9a7ed9ff339e0d983a10d7d6065a09 441 Gene3D G3DSA:3.40.50.300 230 436 2.6E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21345 6a9a7ed9ff339e0d983a10d7d6065a09 441 SUPERFAMILY SSF52540 230 394 4.44E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21345 6a9a7ed9ff339e0d983a10d7d6065a09 441 SUPERFAMILY SSF88723 105 152 9.81E-9 T 06-07-2017 IPR029060 PIN domain-like LK06_RS21345 6a9a7ed9ff339e0d983a10d7d6065a09 441 SUPERFAMILY SSF88723 14 72 9.81E-9 T 06-07-2017 IPR029060 PIN domain-like LK06_RS14840 ed059b8e199e977a092a7f0f908d9b57 510 Gene3D G3DSA:1.10.10.10 136 180 2.2E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14840 ed059b8e199e977a092a7f0f908d9b57 510 Gene3D G3DSA:3.40.33.10 388 500 2.5E-10 T 06-07-2017 IPR014044 CAP domain LK06_RS14840 ed059b8e199e977a092a7f0f908d9b57 510 SUPERFAMILY SSF88946 9 108 5.97E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14840 ed059b8e199e977a092a7f0f908d9b57 510 Pfam PF00188 Cysteine-rich secretory protein family 392 505 2.0E-18 T 06-07-2017 IPR014044 CAP domain LK06_RS14840 ed059b8e199e977a092a7f0f908d9b57 510 Gene3D G3DSA:1.10.1740.10 10 112 1.7E-21 T 06-07-2017 LK06_RS14840 ed059b8e199e977a092a7f0f908d9b57 510 Pfam PF04542 Sigma-70 region 2 26 92 1.6E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS14840 ed059b8e199e977a092a7f0f908d9b57 510 SUPERFAMILY SSF55797 388 503 4.19E-19 T 06-07-2017 IPR014044 CAP domain LK06_RS14840 ed059b8e199e977a092a7f0f908d9b57 510 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 183 1.3E-21 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS00375 3437f410e32559cf4fa3199d691b8d54 303 SUPERFAMILY SSF161098 95 285 1.21E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS00375 3437f410e32559cf4fa3199d691b8d54 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 77 1.0E-12 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LK06_RS00375 3437f410e32559cf4fa3199d691b8d54 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 300 2.8E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS00375 3437f410e32559cf4fa3199d691b8d54 303 Gene3D G3DSA:1.10.3720.10 91 298 1.3E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS16105 c8c72e7197d45061e08845227e09b08c 600 Pfam PF13667 ThiC-associated domain 27 90 6.4E-21 T 06-07-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 LK06_RS16105 c8c72e7197d45061e08845227e09b08c 600 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 136 559 2.2E-211 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 LK06_RS16105 c8c72e7197d45061e08845227e09b08c 600 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 136 563 55.948 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 LK06_RS16105 c8c72e7197d45061e08845227e09b08c 600 Pfam PF01964 Radical SAM ThiC family 137 557 1.4E-199 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 LK06_RS27980 2904f1e1bea87c6f1c5da5363b958631 307 Gene3D G3DSA:3.20.20.60 1 239 6.3E-76 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS27980 2904f1e1bea87c6f1c5da5363b958631 307 SUPERFAMILY SSF51621 1 239 9.94E-64 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS27980 2904f1e1bea87c6f1c5da5363b958631 307 PIRSF PIRSF015582 1 306 2.9E-90 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like LK06_RS27980 2904f1e1bea87c6f1c5da5363b958631 307 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 3 228 8.4E-46 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 LK06_RS07600 d713b6a0c6bc949de2681e5244061611 93 Gene3D G3DSA:3.30.70.920 3 78 8.0E-25 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS07600 d713b6a0c6bc949de2681e5244061611 93 SUPERFAMILY SSF54909 2 78 1.18E-18 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS07600 d713b6a0c6bc949de2681e5244061611 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 1.4E-15 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LK06_RS05930 8c52284adca7e9c30c6ff8e5a8b3ad94 249 Gene3D G3DSA:1.10.530.10 170 246 2.2E-10 T 06-07-2017 LK06_RS05930 8c52284adca7e9c30c6ff8e5a8b3ad94 249 SUPERFAMILY SSF53955 143 243 2.1E-15 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS05930 8c52284adca7e9c30c6ff8e5a8b3ad94 249 Pfam PF01464 Transglycosylase SLT domain 174 246 4.6E-10 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 Pfam PF06723 MreB/Mbl protein 6 330 7.3E-157 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 43 61 7.8E-63 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 294 320 7.8E-63 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 181 201 7.8E-63 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 63 86 7.8E-63 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 126 145 7.8E-63 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 330 2.8E-154 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 Gene3D G3DSA:3.30.420.40 257 311 2.0E-36 T 06-07-2017 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 Gene3D G3DSA:3.30.420.40 154 180 2.0E-36 T 06-07-2017 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 SUPERFAMILY SSF53067 5 142 2.27E-42 T 06-07-2017 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 SUPERFAMILY SSF53067 144 322 7.41E-52 T 06-07-2017 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 Gene3D G3DSA:3.90.640.10 181 253 1.5E-32 T 06-07-2017 LK06_RS09875 a917ec28bf462e42696476f66b023743 339 Gene3D G3DSA:3.30.420.40 6 153 7.4E-48 T 06-07-2017 LK06_RS04100 cb5b89f62ce88ac375c0d0e7e783ff4b 281 SMART SM00934 20 266 9.3E-31 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04100 cb5b89f62ce88ac375c0d0e7e783ff4b 281 Gene3D G3DSA:3.20.20.70 9 272 5.4E-58 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS04100 cb5b89f62ce88ac375c0d0e7e783ff4b 281 SUPERFAMILY SSF51366 7 269 4.71E-59 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 LK06_RS04100 cb5b89f62ce88ac375c0d0e7e783ff4b 281 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 94 107 - T 06-07-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04100 cb5b89f62ce88ac375c0d0e7e783ff4b 281 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 5 280 33.095 T 06-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 LK06_RS04100 cb5b89f62ce88ac375c0d0e7e783ff4b 281 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 20 264 1.3E-35 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LK06_RS04100 cb5b89f62ce88ac375c0d0e7e783ff4b 281 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 7 264 5.7E-81 T 06-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 LK06_RS14765 5e1e27c81ed0307bac3ba804b04f32ba 341 Pfam PF00953 Glycosyl transferase family 4 76 213 6.5E-12 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 LK06_RS05520 35f62d19b599b6d5f255400a6ec538c7 323 SUPERFAMILY SSF100879 181 275 2.16E-13 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS05520 35f62d19b599b6d5f255400a6ec538c7 323 Pfam PF11799 impB/mucB/samB family C-terminal domain 177 288 5.5E-11 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS05520 35f62d19b599b6d5f255400a6ec538c7 323 Gene3D G3DSA:3.30.1490.100 181 286 4.8E-15 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS05520 35f62d19b599b6d5f255400a6ec538c7 323 Pfam PF00817 impB/mucB/samB family 14 89 2.5E-5 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LK06_RS05520 35f62d19b599b6d5f255400a6ec538c7 323 Gene3D G3DSA:3.30.70.270 14 99 3.6E-6 T 06-07-2017 LK06_RS05520 35f62d19b599b6d5f255400a6ec538c7 323 Gene3D G3DSA:1.10.150.20 103 173 3.2E-18 T 06-07-2017 LK06_RS05520 35f62d19b599b6d5f255400a6ec538c7 323 SUPERFAMILY SSF56672 13 170 1.02E-29 T 06-07-2017 LK06_RS12705 7c7974827dc24d90df5262cc52fbf7e7 353 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 65 212 5.7E-29 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LK06_RS12705 7c7974827dc24d90df5262cc52fbf7e7 353 Gene3D G3DSA:3.40.50.970 27 249 5.6E-84 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS12705 7c7974827dc24d90df5262cc52fbf7e7 353 SUPERFAMILY SSF52518 29 352 4.11E-85 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS08385 c46124275c37e18660b33e3bab97253f 119 Pfam PF01548 Transposase 18 119 3.1E-14 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS17255 421b264b22e552f8bf489f8dbe6dc4c9 211 Pfam PF00925 GTP cyclohydrolase II 25 175 3.1E-59 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS17255 421b264b22e552f8bf489f8dbe6dc4c9 211 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 6 202 35.11 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS17255 421b264b22e552f8bf489f8dbe6dc4c9 211 SUPERFAMILY SSF142695 25 176 5.49E-56 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 LK06_RS16100 ac46670aacec4f50867a6d71800c4a01 475 Pfam PF07907 YibE/F-like protein 204 441 1.4E-73 T 06-07-2017 IPR012507 YibE/F-like LK06_RS01740 6104b951375ca55b1e836cc560c4dce5 131 SUPERFAMILY SSF109604 15 61 2.04E-6 T 06-07-2017 LK06_RS23250 4b4e2d3c76189b8ba2fcb79f82074cfd 215 Gene3D G3DSA:3.90.870.10 6 204 6.7E-64 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain LK06_RS23250 4b4e2d3c76189b8ba2fcb79f82074cfd 215 SUPERFAMILY SSF55821 4 210 2.47E-56 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain LK06_RS23250 4b4e2d3c76189b8ba2fcb79f82074cfd 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 13 207 5.9E-56 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 LK06_RS23250 4b4e2d3c76189b8ba2fcb79f82074cfd 215 Pfam PF01300 Telomere recombination 23 197 7.6E-46 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 LK06_RS30590 84e5b8f4e4211646b7275c6c4e661338 266 Gene3D G3DSA:3.90.226.10 5 205 2.7E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS30590 84e5b8f4e4211646b7275c6c4e661338 266 Gene3D G3DSA:1.10.12.10 209 264 3.4E-16 T 06-07-2017 IPR014748 Crontonase, C-terminal LK06_RS30590 84e5b8f4e4211646b7275c6c4e661338 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 264 1.3E-53 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS30590 84e5b8f4e4211646b7275c6c4e661338 266 SUPERFAMILY SSF52096 4 264 7.04E-80 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS27890 155e06b992d336ed52a3c870b8494953 169 Gene3D G3DSA:3.40.220.10 3 168 1.4E-62 T 06-07-2017 LK06_RS27890 155e06b992d336ed52a3c870b8494953 169 SUPERFAMILY SSF52949 3 168 5.55E-58 T 06-07-2017 LK06_RS27890 155e06b992d336ed52a3c870b8494953 169 Pfam PF01661 Macro domain 20 137 2.9E-41 T 06-07-2017 IPR002589 Macro domain LK06_RS27890 155e06b992d336ed52a3c870b8494953 169 SMART SM00506 3 137 1.9E-53 T 06-07-2017 IPR002589 Macro domain LK06_RS17900 10c28740966b7f8939a23b9097929590 243 Gene3D G3DSA:3.90.550.10 11 239 9.8E-54 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS17900 10c28740966b7f8939a23b9097929590 243 SUPERFAMILY SSF53448 11 238 9.32E-53 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS17900 10c28740966b7f8939a23b9097929590 243 Pfam PF00483 Nucleotidyl transferase 13 239 5.4E-25 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LK06_RS01765 10b3999c50d56a4aa863a80ebe053e9f 384 SUPERFAMILY SSF103481 37 113 2.88E-6 T 06-07-2017 LK06_RS01765 10b3999c50d56a4aa863a80ebe053e9f 384 Pfam PF05653 Magnesium transporter NIPA 32 108 1.8E-7 T 06-07-2017 IPR008521 Magnesium transporter NIPA GO:0015095|GO:0015693|GO:0016021 Reactome: R-HSA-5223345 LK06_RS02090 166e870f181b93631e110701eb588029 483 Pfam PF00082 Subtilase family 187 445 7.0E-17 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS02090 166e870f181b93631e110701eb588029 483 SUPERFAMILY SSF52743 148 450 1.96E-39 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS02090 166e870f181b93631e110701eb588029 483 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 417 427 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site LK06_RS02090 166e870f181b93631e110701eb588029 483 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 200 210 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site LK06_RS02090 166e870f181b93631e110701eb588029 483 PRINTS PR00723 Subtilisin serine protease family (S8) signature 154 173 2.2E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS02090 166e870f181b93631e110701eb588029 483 PRINTS PR00723 Subtilisin serine protease family (S8) signature 196 209 2.2E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS02090 166e870f181b93631e110701eb588029 483 PRINTS PR00723 Subtilisin serine protease family (S8) signature 416 432 2.2E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS02090 166e870f181b93631e110701eb588029 483 Gene3D G3DSA:3.40.50.200 412 452 2.7E-34 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS02090 166e870f181b93631e110701eb588029 483 Gene3D G3DSA:3.40.50.200 155 359 2.7E-34 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS06915 8f7662279960aba2dcc2214e74869059 325 SUPERFAMILY SSF52540 4 251 2.11E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06915 8f7662279960aba2dcc2214e74869059 325 SMART SM00382 30 228 3.8E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS06915 8f7662279960aba2dcc2214e74869059 325 Pfam PF00005 ABC transporter 22 181 7.5E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS06915 8f7662279960aba2dcc2214e74869059 325 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 251 3.3E-6 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LK06_RS06915 8f7662279960aba2dcc2214e74869059 325 Gene3D G3DSA:3.40.50.300 2 247 1.2E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 7 140 5.5E-48 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 144 355 1.5E-81 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 SUPERFAMILY SSF51735 140 306 5.91E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 Gene3D G3DSA:3.40.50.1770 5 179 1.2E-58 T 06-07-2017 LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 5 371 1.1E-172 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 SMART SM01002 152 300 2.0E-82 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 SUPERFAMILY SSF52283 5 140 6.38E-67 T 06-07-2017 LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 SUPERFAMILY SSF52283 308 363 6.38E-67 T 06-07-2017 LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 7 33 - T 06-07-2017 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 Gene3D G3DSA:3.50.50.60 180 202 2.0E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 SMART SM01003 7 140 1.2E-80 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 Gene3D G3DSA:3.40.50.1770 203 360 2.3E-29 T 06-07-2017 LK06_RS05705 cda61d0c496b41cb0b381f7e2b7910f8 374 PIRSF PIRSF000183 4 374 7.1E-167 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 LK06_RS20680 a48bd3800c6ce0840d8813878d42a68d 351 Gene3D G3DSA:3.40.50.2300 175 253 4.1E-5 T 06-07-2017 LK06_RS20680 a48bd3800c6ce0840d8813878d42a68d 351 SUPERFAMILY SSF53822 57 264 1.53E-13 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS20680 a48bd3800c6ce0840d8813878d42a68d 351 Gene3D G3DSA:3.40.50.2300 41 174 5.5E-47 T 06-07-2017 LK06_RS20680 a48bd3800c6ce0840d8813878d42a68d 351 Pfam PF02608 Basic membrane protein 50 349 1.3E-59 T 06-07-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 LK06_RS04835 95ee787a55be412e4a7423a35ea8d5b3 243 Pfam PF07179 SseB protein N-terminal domain 22 142 1.8E-30 T 06-07-2017 IPR009839 SseB protein N-terminal domain LK06_RS11070 c27d9143cd9847cd5ad5e47889d8bd52 230 Pfam PF00005 ABC transporter 26 174 3.1E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS11070 c27d9143cd9847cd5ad5e47889d8bd52 230 SMART SM00382 35 225 1.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS11070 c27d9143cd9847cd5ad5e47889d8bd52 230 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS11070 c27d9143cd9847cd5ad5e47889d8bd52 230 Gene3D G3DSA:3.40.50.300 5 227 4.2E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11070 c27d9143cd9847cd5ad5e47889d8bd52 230 SUPERFAMILY SSF52540 7 226 1.01E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14985 144a17d848f878d70f7c7fb6bba9e47a 95 Pfam PF04248 Domain of unknown function (DUF427) 2 88 4.8E-28 T 06-07-2017 IPR007361 Domain of unknown function DUF427 LK06_RS20960 3e168f5108c0a0cc8101f76279e45e50 386 Gene3D G3DSA:3.90.1150.10 255 385 1.4E-48 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS20960 3e168f5108c0a0cc8101f76279e45e50 386 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 198 212 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LK06_RS20960 3e168f5108c0a0cc8101f76279e45e50 386 Gene3D G3DSA:3.40.640.10 10 252 8.8E-103 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS20960 3e168f5108c0a0cc8101f76279e45e50 386 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 385 1.1E-148 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LK06_RS20960 3e168f5108c0a0cc8101f76279e45e50 386 SUPERFAMILY SSF53383 13 385 8.07E-124 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS20960 3e168f5108c0a0cc8101f76279e45e50 386 PIRSF PIRSF001434 2 386 4.1E-145 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LK06_RS20715 b65299b31dff6e7a80cd8ba09985441f 125 SUPERFAMILY SSF52091 17 101 5.3E-7 T 06-07-2017 IPR002645 STAS domain LK06_RS20715 b65299b31dff6e7a80cd8ba09985441f 125 Gene3D G3DSA:3.30.750.24 18 110 6.8E-5 T 06-07-2017 IPR002645 STAS domain LK06_RS20715 b65299b31dff6e7a80cd8ba09985441f 125 Pfam PF13466 STAS domain 20 100 1.5E-10 T 06-07-2017 IPR002645 STAS domain LK06_RS06610 4b074f46020f9811f3c39941e6f13daf 78 Pfam PF03840 Preprotein translocase SecG subunit 5 73 7.2E-20 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LK06_RS06610 4b074f46020f9811f3c39941e6f13daf 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 5 73 1.0E-20 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LK06_RS06610 4b074f46020f9811f3c39941e6f13daf 78 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.1E-6 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LK06_RS06610 4b074f46020f9811f3c39941e6f13daf 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.1E-6 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LK06_RS06610 4b074f46020f9811f3c39941e6f13daf 78 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 1.1E-6 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LK06_RS06610 4b074f46020f9811f3c39941e6f13daf 78 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 1.1E-6 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LK06_RS30580 2563c8dda5438a9541cc3cd395907f85 278 Pfam PF00561 alpha/beta hydrolase fold 23 264 3.5E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS30580 2563c8dda5438a9541cc3cd395907f85 278 Gene3D G3DSA:3.40.50.1820 3 276 3.9E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30580 2563c8dda5438a9541cc3cd395907f85 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 8.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS30580 2563c8dda5438a9541cc3cd395907f85 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 8.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS30580 2563c8dda5438a9541cc3cd395907f85 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 8.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS30580 2563c8dda5438a9541cc3cd395907f85 278 SUPERFAMILY SSF53474 4 276 7.13E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS16135 1491dd151bbe86d455eea8a7ed5030c1 502 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 473 1.2E-178 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 LK06_RS11480 7fb5910063985255f3ba0a167f288ad9 131 Gene3D G3DSA:3.30.565.10 12 127 1.8E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11480 7fb5910063985255f3ba0a167f288ad9 131 SUPERFAMILY SSF55874 22 126 9.99E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11480 7fb5910063985255f3ba0a167f288ad9 131 Pfam PF13581 Histidine kinase-like ATPase domain 11 128 1.8E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21260 9ef94d8749aee4002d9e537f99f156f9 419 Gene3D G3DSA:3.40.50.2300 2 128 3.2E-8 T 06-07-2017 LK06_RS21260 9ef94d8749aee4002d9e537f99f156f9 419 SUPERFAMILY SSF52540 150 385 6.11E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21260 9ef94d8749aee4002d9e537f99f156f9 419 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 152 331 3.0E-20 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain LK06_RS21260 9ef94d8749aee4002d9e537f99f156f9 419 SUPERFAMILY SSF52172 2 130 8.64E-9 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS21260 9ef94d8749aee4002d9e537f99f156f9 419 Gene3D G3DSA:3.40.50.300 149 385 2.7E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20095 6fc6889c17051a19a0726906da3d03bc 319 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 81 238 3.3E-58 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS20095 6fc6889c17051a19a0726906da3d03bc 319 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 82 238 1.2E-47 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS12110 4c678fcf8ec2b0d50d71b236d7d9bf69 163 Gene3D G3DSA:3.30.450.30 1 126 4.9E-32 T 06-07-2017 LK06_RS12110 4c678fcf8ec2b0d50d71b236d7d9bf69 163 SUPERFAMILY SSF103196 2 126 8.2E-25 T 06-07-2017 LK06_RS12110 4c678fcf8ec2b0d50d71b236d7d9bf69 163 Pfam PF03259 Roadblock/LC7 domain 13 99 1.5E-17 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS12110 4c678fcf8ec2b0d50d71b236d7d9bf69 163 SMART SM00960 11 99 8.2E-17 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS10395 e00aff57d3cad68b7904fbda2fa77a1b 302 Pfam PF03777 Small secreted domain (DUF320) 25 80 6.2E-26 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS10395 e00aff57d3cad68b7904fbda2fa77a1b 302 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 264 296 3.3E-4 T 06-07-2017 IPR019931 LPXTG cell wall anchor domain LK06_RS10395 e00aff57d3cad68b7904fbda2fa77a1b 302 SUPERFAMILY SSF69349 137 250 3.69E-5 T 06-07-2017 LK06_RS28240 96edc9bdd3be1ffeebc55cf0d530d097 315 Gene3D G3DSA:3.40.47.10 161 314 6.5E-40 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28240 96edc9bdd3be1ffeebc55cf0d530d097 315 Gene3D G3DSA:3.40.47.10 4 160 9.9E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28240 96edc9bdd3be1ffeebc55cf0d530d097 315 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 225 313 3.9E-27 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS28240 96edc9bdd3be1ffeebc55cf0d530d097 315 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 313 8.7E-92 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS28240 96edc9bdd3be1ffeebc55cf0d530d097 315 SUPERFAMILY SSF53901 4 314 3.67E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS28240 96edc9bdd3be1ffeebc55cf0d530d097 315 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 185 1.1E-27 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS28240 96edc9bdd3be1ffeebc55cf0d530d097 315 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 314 59.309 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS13580 f509196d3fa02bb3d01852c3f037e245 285 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 39 283 4.0E-135 T 06-07-2017 LK06_RS04665 490e265f193793ee14d710a527f861af 450 SUPERFAMILY SSF63380 228 323 1.16E-14 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS04665 490e265f193793ee14d710a527f861af 450 Pfam PF00175 Oxidoreductase NAD-binding domain 336 429 5.3E-7 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LK06_RS04665 490e265f193793ee14d710a527f861af 450 SUPERFAMILY SSF52343 314 446 1.11E-24 T 06-07-2017 LK06_RS04665 490e265f193793ee14d710a527f861af 450 Pfam PF01794 Ferric reductase like transmembrane component 69 183 3.1E-16 T 06-07-2017 IPR013130 Ferric reductase transmembrane component-like domain LK06_RS04665 490e265f193793ee14d710a527f861af 450 Gene3D G3DSA:3.40.50.80 317 444 2.7E-23 T 06-07-2017 LK06_RS04665 490e265f193793ee14d710a527f861af 450 Gene3D G3DSA:2.40.30.10 230 316 8.6E-12 T 06-07-2017 LK06_RS06875 7ffb39725cddff8b9a2e2f42e21a8fd9 202 Pfam PF13803 Domain of unknown function (DUF4184) 1 97 2.4E-10 T 06-07-2017 IPR025238 Protein of unknown function DUF4184 LK06_RS18235 a13e8af225e8c1c040b7c29add79fed4 314 SUPERFAMILY SSF49785 196 305 1.46E-9 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS18235 a13e8af225e8c1c040b7c29add79fed4 314 Gene3D G3DSA:2.60.120.260 187 303 5.5E-11 T 06-07-2017 IPR008979 Galactose-binding domain-like LK06_RS09410 2a9ce8e493bca11dd9be12fe3f7e262d 342 Pfam PF06030 Bacterial protein of unknown function (DUF916) 46 143 1.4E-8 T 06-07-2017 IPR010317 Protein of unknown function DUF916, cell surface putative LK06_RS13245 c812ee00449d466983f8cbec4cf59a57 139 SUPERFAMILY SSF52788 7 130 3.14E-37 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily LK06_RS13245 c812ee00449d466983f8cbec4cf59a57 139 Gene3D G3DSA:3.40.50.270 8 130 1.8E-40 T 06-07-2017 LK06_RS13245 c812ee00449d466983f8cbec4cf59a57 139 SMART SM00226 7 132 8.9E-47 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily LK06_RS13245 c812ee00449d466983f8cbec4cf59a57 139 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 9 129 1.7E-22 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily LK06_RS03255 b1e4aac7bab8fce719907b6d48e4a4d4 352 Pfam PF00152 tRNA synthetases class II (D, K and N) 91 335 9.9E-33 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS03255 b1e4aac7bab8fce719907b6d48e4a4d4 352 Gene3D G3DSA:3.30.930.10 73 339 9.9E-44 T 06-07-2017 LK06_RS03255 b1e4aac7bab8fce719907b6d48e4a4d4 352 SUPERFAMILY SSF55681 29 335 4.66E-49 T 06-07-2017 LK06_RS27790 d5eacd0bb94069d34e40e14374522504 211 Gene3D G3DSA:3.60.15.10 1 177 7.9E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS27790 d5eacd0bb94069d34e40e14374522504 211 SUPERFAMILY SSF56281 87 193 4.19E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS27790 d5eacd0bb94069d34e40e14374522504 211 SUPERFAMILY SSF56281 1 60 4.19E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS27790 d5eacd0bb94069d34e40e14374522504 211 SMART SM00849 7 176 4.7E-5 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS27790 d5eacd0bb94069d34e40e14374522504 211 Pfam PF13483 Beta-lactamase superfamily domain 2 176 2.2E-22 T 06-07-2017 LK06_RS29855 2357c10571d62a43154d1529b29e1fc0 254 Pfam PF07848 PaaX-like protein 17 78 2.6E-16 T 06-07-2017 IPR012906 PaaX-like, N-terminal LK06_RS29855 2357c10571d62a43154d1529b29e1fc0 254 Pfam PF08223 PaaX-like protein C-terminal domain 95 240 2.6E-15 T 06-07-2017 IPR013225 PaaX-like, C-terminal LK06_RS12980 7af7c7f3873c4a09ef0ea2914a84aff9 231 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 24 39 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 LK06_RS12980 7af7c7f3873c4a09ef0ea2914a84aff9 231 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 229 35.34 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 LK06_RS12980 7af7c7f3873c4a09ef0ea2914a84aff9 231 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 229 1.2E-74 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 LK06_RS12980 7af7c7f3873c4a09ef0ea2914a84aff9 231 Gene3D G3DSA:3.40.50.150 12 228 1.2E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS12980 7af7c7f3873c4a09ef0ea2914a84aff9 231 SUPERFAMILY SSF53335 4 227 2.01E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS12980 7af7c7f3873c4a09ef0ea2914a84aff9 231 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 229 1.8E-62 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 LK06_RS12980 7af7c7f3873c4a09ef0ea2914a84aff9 231 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 LK06_RS08840 f026b4038ea4dcc1a22ef208282aa9c5 217 Pfam PF02678 Pirin 16 119 3.5E-28 T 06-07-2017 IPR003829 Pirin, N-terminal domain LK06_RS08840 f026b4038ea4dcc1a22ef208282aa9c5 217 Gene3D G3DSA:2.60.120.10 150 215 9.3E-6 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS08840 f026b4038ea4dcc1a22ef208282aa9c5 217 Gene3D G3DSA:2.60.120.10 14 133 2.5E-36 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS08840 f026b4038ea4dcc1a22ef208282aa9c5 217 SUPERFAMILY SSF51182 16 215 1.64E-45 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS02820 8f8041247e3302d028b547e072bab49a 339 Pfam PF01636 Phosphotransferase enzyme family 21 263 2.9E-19 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS02820 8f8041247e3302d028b547e072bab49a 339 Gene3D G3DSA:3.90.1200.10 113 289 4.7E-17 T 06-07-2017 LK06_RS02820 8f8041247e3302d028b547e072bab49a 339 SUPERFAMILY SSF56112 4 287 2.6E-27 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS31665 72564468c6cd83aa8c9aa5532ca41f8a 141 Pfam PF01810 LysE type translocator 11 120 1.6E-23 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 LK06_RS18255 acb7fe4cd6fa23eeb83bb5d268d07a9e 420 Pfam PF13416 Bacterial extracellular solute-binding protein 46 348 1.4E-40 T 06-07-2017 LK06_RS18255 acb7fe4cd6fa23eeb83bb5d268d07a9e 420 Gene3D G3DSA:3.40.190.10 35 152 2.0E-7 T 06-07-2017 LK06_RS18255 acb7fe4cd6fa23eeb83bb5d268d07a9e 420 SUPERFAMILY SSF53850 37 410 4.61E-62 T 06-07-2017 LK06_RS18255 acb7fe4cd6fa23eeb83bb5d268d07a9e 420 Gene3D G3DSA:3.40.190.10 153 345 9.2E-38 T 06-07-2017 LK06_RS18255 acb7fe4cd6fa23eeb83bb5d268d07a9e 420 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 133 150 - T 06-07-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 LK06_RS10700 637157453c2d9766de86dbb13eaba2b7 288 SUPERFAMILY SSF54637 5 114 1.13E-43 T 06-07-2017 IPR029069 HotDog domain LK06_RS10700 637157453c2d9766de86dbb13eaba2b7 288 Pfam PF13622 Thioesterase-like superfamily 33 284 2.5E-60 T 06-07-2017 LK06_RS10700 637157453c2d9766de86dbb13eaba2b7 288 SUPERFAMILY SSF54637 116 287 3.84E-46 T 06-07-2017 IPR029069 HotDog domain LK06_RS10700 637157453c2d9766de86dbb13eaba2b7 288 Gene3D G3DSA:3.10.129.10 125 287 1.7E-50 T 06-07-2017 IPR029069 HotDog domain LK06_RS10700 637157453c2d9766de86dbb13eaba2b7 288 Gene3D G3DSA:3.10.129.10 5 115 8.6E-50 T 06-07-2017 IPR029069 HotDog domain LK06_RS10700 637157453c2d9766de86dbb13eaba2b7 288 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 12 285 2.9E-88 T 06-07-2017 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-75105 LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 76 9.0E-17 T 06-07-2017 LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 SUPERFAMILY SSF54747 5 75 7.59E-30 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 4.2E-25 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 SUPERFAMILY SSF46906 70 143 3.92E-27 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.467 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 SMART SM00649 12 143 9.0E-86 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 6.1E-29 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 Gene3D G3DSA:3.30.1550.10 5 74 3.9E-38 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 Gene3D G3DSA:1.10.10.250 75 143 3.5E-32 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 143 2.0E-63 T 06-07-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12455 f0613b7786b4424964f1b4ae956ecb9a 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 06-07-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 SUPERFAMILY SSF103473 256 428 3.14E-58 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 SUPERFAMILY SSF103473 495 518 3.14E-58 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 SUPERFAMILY SSF103473 2 189 3.14E-58 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 Gene3D G3DSA:1.20.1250.20 3 181 3.9E-26 T 06-07-2017 LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 Pfam PF07690 Major Facilitator Superfamily 12 418 4.0E-47 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 9 33 4.7E-10 T 06-07-2017 LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 69 91 4.7E-10 T 06-07-2017 LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 4.7E-10 T 06-07-2017 LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 4.7E-10 T 06-07-2017 LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 Gene3D G3DSA:1.20.1250.20 496 515 1.1E-18 T 06-07-2017 LK06_RS30250 f6364cc6de76fb7d897d129038fcc6b5 541 Gene3D G3DSA:1.20.1250.20 261 434 1.1E-18 T 06-07-2017 LK06_RS22360 f327f2a8a5d942251c193481d4719e5f 438 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 23 436 1.0E-109 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 LK06_RS22360 f327f2a8a5d942251c193481d4719e5f 438 SUPERFAMILY SSF55205 15 435 1.44E-99 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 LK06_RS22360 f327f2a8a5d942251c193481d4719e5f 438 PIRSF PIRSF000505 8 438 1.6E-110 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 LK06_RS22360 f327f2a8a5d942251c193481d4719e5f 438 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 18 438 28.48 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 LK06_RS22360 f327f2a8a5d942251c193481d4719e5f 438 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 17 430 4.6E-105 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 LK06_RS22360 f327f2a8a5d942251c193481d4719e5f 438 ProSitePatterns PS00885 EPSP synthase signature 2. 351 369 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 LK06_RS22360 f327f2a8a5d942251c193481d4719e5f 438 ProSitePatterns PS00104 EPSP synthase signature 1. 98 112 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 LK06_RS22360 f327f2a8a5d942251c193481d4719e5f 438 Gene3D G3DSA:3.65.10.10 30 250 2.6E-62 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 LK06_RS22360 f327f2a8a5d942251c193481d4719e5f 438 Gene3D G3DSA:3.65.10.10 251 434 7.6E-51 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 LK06_RS30620 e1abe8ab00caab1f31994767248dd408 220 SUPERFAMILY SSF46689 6 75 2.15E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS30620 e1abe8ab00caab1f31994767248dd408 220 Gene3D G3DSA:1.10.357.10 7 197 1.4E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS30620 e1abe8ab00caab1f31994767248dd408 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 2.5E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30620 e1abe8ab00caab1f31994767248dd408 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.4E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30620 e1abe8ab00caab1f31994767248dd408 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.4E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS20600 c954cd082e2690c5843c372742cb9a47 888 Gene3D G3DSA:3.40.50.2000 571 711 3.7E-9 T 06-07-2017 LK06_RS20600 c954cd082e2690c5843c372742cb9a47 888 SUPERFAMILY SSF53756 421 736 1.41E-30 T 06-07-2017 LK06_RS20600 c954cd082e2690c5843c372742cb9a47 888 Pfam PF13692 Glycosyl transferases group 1 575 711 8.9E-13 T 06-07-2017 LK06_RS04695 16f5b2429555473b15355e27f4153cbc 401 SUPERFAMILY SSF53383 2 387 7.01E-118 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS04695 16f5b2429555473b15355e27f4153cbc 401 Gene3D G3DSA:3.90.1150.10 2 57 1.3E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS04695 16f5b2429555473b15355e27f4153cbc 401 Gene3D G3DSA:3.90.1150.10 299 388 1.3E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS04695 16f5b2429555473b15355e27f4153cbc 401 Gene3D G3DSA:3.40.640.10 58 295 7.9E-85 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS04695 16f5b2429555473b15355e27f4153cbc 401 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 388 42.707 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 LK06_RS04695 16f5b2429555473b15355e27f4153cbc 401 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 214 252 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS04695 16f5b2429555473b15355e27f4153cbc 401 Pfam PF00202 Aminotransferase class-III 20 385 2.7E-104 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS04695 16f5b2429555473b15355e27f4153cbc 401 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 14 387 7.5E-135 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 LK06_RS00875 00057f49538884e5c995f4be28765833 624 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 53 249 2.0E-11 T 06-07-2017 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 8 484 5.0E-71 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 SUPERFAMILY SSF103473 469 494 2.75E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 SUPERFAMILY SSF103473 2 196 2.75E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 SUPERFAMILY SSF103473 242 412 2.75E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 Pfam PF07690 Major Facilitator Superfamily 12 402 7.5E-51 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 2.3E-9 T 06-07-2017 LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 2.3E-9 T 06-07-2017 LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 2.3E-9 T 06-07-2017 LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 Gene3D G3DSA:1.20.1250.20 258 413 1.9E-23 T 06-07-2017 LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 Gene3D G3DSA:1.20.1250.20 470 494 1.9E-23 T 06-07-2017 LK06_RS26395 5531a5cdb010a80541c05d4c6b1d1b26 520 Gene3D G3DSA:1.20.1250.20 4 185 1.4E-29 T 06-07-2017 LK06_RS15710 fd7c0dd722ef819af9544f034ab7b31e 252 Pfam PF00535 Glycosyl transferase family 2 7 112 3.4E-10 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS15710 fd7c0dd722ef819af9544f034ab7b31e 252 Gene3D G3DSA:3.90.550.10 4 222 1.0E-23 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS15710 fd7c0dd722ef819af9544f034ab7b31e 252 SUPERFAMILY SSF53448 4 217 2.63E-24 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS04650 a1a2b8ad12cf1f9a5ca3a4491126a5ed 234 Pfam PF03734 L,D-transpeptidase catalytic domain 81 219 2.0E-5 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 LK06_RS09455 0240124673274f7b4a9d44a4ab03cfe6 382 Pfam PF00294 pfkB family carbohydrate kinase 44 324 1.4E-34 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB LK06_RS09455 0240124673274f7b4a9d44a4ab03cfe6 382 Gene3D G3DSA:3.40.1190.20 40 337 3.2E-59 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS09455 0240124673274f7b4a9d44a4ab03cfe6 382 SUPERFAMILY SSF53613 39 333 4.52E-53 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS09455 0240124673274f7b4a9d44a4ab03cfe6 382 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 277 290 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 LK06_RS22535 669a21fe17007c190087af6957ce3df3 131 Gene3D G3DSA:1.20.120.400 15 130 1.8E-49 T 06-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 LK06_RS22535 669a21fe17007c190087af6957ce3df3 131 Pfam PF09055 Nickel-containing superoxide dismutase 11 129 1.0E-42 T 06-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 LK06_RS22535 669a21fe17007c190087af6957ce3df3 131 TIGRFAM TIGR02753 sodN: superoxide dismutase, Ni 1 131 1.7E-58 T 06-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 LK06_RS22535 669a21fe17007c190087af6957ce3df3 131 SUPERFAMILY SSF109770 15 131 6.8E-54 T 06-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 LK06_RS20520 96e24a6c1f15b102ab424bbc6c4b7260 514 Gene3D G3DSA:3.10.105.10 275 483 2.9E-47 T 06-07-2017 LK06_RS20520 96e24a6c1f15b102ab424bbc6c4b7260 514 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 72 431 4.1E-71 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS20520 96e24a6c1f15b102ab424bbc6c4b7260 514 SUPERFAMILY SSF53850 27 510 7.71E-100 T 06-07-2017 LK06_RS20520 96e24a6c1f15b102ab424bbc6c4b7260 514 PIRSF PIRSF002741 6 513 5.3E-70 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LK06_RS20520 96e24a6c1f15b102ab424bbc6c4b7260 514 Gene3D G3DSA:3.90.76.10 40 196 5.8E-32 T 06-07-2017 LK06_RS28800 6472634a980d34521fb7c37921158313 206 SUPERFAMILY SSF46689 6 85 1.95E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS28800 6472634a980d34521fb7c37921158313 206 Gene3D G3DSA:1.10.357.10 10 195 5.5E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS28800 6472634a980d34521fb7c37921158313 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 5.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS28800 6472634a980d34521fb7c37921158313 206 SUPERFAMILY SSF48498 82 193 1.75E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS28800 6472634a980d34521fb7c37921158313 206 Pfam PF13977 Bacterial transcriptional repressor 85 194 2.9E-24 T 06-07-2017 LK06_RS28800 6472634a980d34521fb7c37921158313 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS28800 6472634a980d34521fb7c37921158313 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS20795 20a94a8fd5aa90291ac0b48afefef407 476 Pfam PF00171 Aldehyde dehydrogenase family 32 475 5.1E-166 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS20795 20a94a8fd5aa90291ac0b48afefef407 476 Gene3D G3DSA:3.40.605.10 20 269 5.3E-100 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS20795 20a94a8fd5aa90291ac0b48afefef407 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 LK06_RS20795 20a94a8fd5aa90291ac0b48afefef407 476 SUPERFAMILY SSF53720 18 475 3.93E-165 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS20795 20a94a8fd5aa90291ac0b48afefef407 476 Gene3D G3DSA:3.40.309.10 270 454 9.5E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS09850 add685cf48845d6311b821fc15bbaafc 498 SUPERFAMILY SSF55154 6 209 1.44E-44 T 06-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 LK06_RS09850 add685cf48845d6311b821fc15bbaafc 498 Gene3D G3DSA:2.40.320.10 6 204 7.7E-55 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 LK06_RS09850 add685cf48845d6311b821fc15bbaafc 498 Pfam PF01928 CYTH domain 6 176 3.0E-13 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 LK06_RS09850 add685cf48845d6311b821fc15bbaafc 498 SMART SM00880 219 483 2.1E-56 T 06-07-2017 IPR007899 CHAD domain LK06_RS09850 add685cf48845d6311b821fc15bbaafc 498 SMART SM01118 5 200 1.1E-13 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 LK06_RS09850 add685cf48845d6311b821fc15bbaafc 498 Pfam PF05235 CHAD domain 219 451 7.2E-47 T 06-07-2017 IPR007899 CHAD domain LK06_RS13575 07edc095935c2425edc389464d806b9a 310 Gene3D G3DSA:3.30.420.40 1 123 7.8E-34 T 06-07-2017 LK06_RS13575 07edc095935c2425edc389464d806b9a 310 Gene3D G3DSA:3.30.420.150 124 306 1.1E-48 T 06-07-2017 LK06_RS13575 07edc095935c2425edc389464d806b9a 310 SUPERFAMILY SSF53067 2 125 5.83E-31 T 06-07-2017 LK06_RS13575 07edc095935c2425edc389464d806b9a 310 SUPERFAMILY SSF53067 129 307 9.06E-36 T 06-07-2017 LK06_RS13575 07edc095935c2425edc389464d806b9a 310 Pfam PF02541 Ppx/GppA phosphatase family 26 305 3.1E-71 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 LK06_RS31390 f7567a560ed01c7c6f3432b829283a52 674 Pfam PF05506 Domain of unknown function (DUF756) 579 664 5.2E-19 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 LK06_RS31390 f7567a560ed01c7c6f3432b829283a52 674 Pfam PF05506 Domain of unknown function (DUF756) 472 569 3.8E-18 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 LK06_RS31390 f7567a560ed01c7c6f3432b829283a52 674 Pfam PF04185 Phosphoesterase family 43 398 3.1E-99 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 LK06_RS31390 f7567a560ed01c7c6f3432b829283a52 674 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 673 8.7E-206 T 06-07-2017 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 LK06_RS24100 e05326140ad9e336846009428fe68146 191 SUPERFAMILY SSF52540 15 188 5.9E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24100 e05326140ad9e336846009428fe68146 191 Pfam PF03029 Conserved hypothetical ATP binding protein 19 186 5.7E-28 T 06-07-2017 IPR004130 GPN-loop GTPase LK06_RS24100 e05326140ad9e336846009428fe68146 191 Gene3D G3DSA:3.40.50.300 11 185 1.5E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13710 a047d09eb4d5dd027f1c6c500f975f8c 333 Gene3D G3DSA:1.10.1040.20 181 279 5.3E-32 T 06-07-2017 IPR018931 Domain of unknown function DUF2520 LK06_RS13710 a047d09eb4d5dd027f1c6c500f975f8c 333 Gene3D G3DSA:3.40.50.720 16 179 6.1E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13710 a047d09eb4d5dd027f1c6c500f975f8c 333 Pfam PF10728 Domain of unknown function (DUF2520) 149 275 1.3E-38 T 06-07-2017 IPR018931 Domain of unknown function DUF2520 LK06_RS13710 a047d09eb4d5dd027f1c6c500f975f8c 333 Pfam PF10727 Rossmann-like domain 7 132 1.7E-43 T 06-07-2017 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain LK06_RS13710 a047d09eb4d5dd027f1c6c500f975f8c 333 SUPERFAMILY SSF51735 18 181 5.31E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13710 a047d09eb4d5dd027f1c6c500f975f8c 333 SUPERFAMILY SSF48179 182 281 3.26E-24 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 LK06_RS00355 e7f67d1b750175cca671e7ffbe010e25 257 SUPERFAMILY SSF53448 2 230 6.49E-48 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS00355 e7f67d1b750175cca671e7ffbe010e25 257 Pfam PF00535 Glycosyl transferase family 2 5 114 3.5E-28 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS00355 e7f67d1b750175cca671e7ffbe010e25 257 Gene3D G3DSA:3.90.550.10 2 232 5.7E-47 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS07210 e8a6b407c34e025311d35d8643d04f78 269 Pfam PF13462 Thioredoxin 82 264 3.1E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS07210 e8a6b407c34e025311d35d8643d04f78 269 SUPERFAMILY SSF52833 80 249 7.07E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS07210 e8a6b407c34e025311d35d8643d04f78 269 Gene3D G3DSA:3.40.30.10 83 268 9.4E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS17440 da931a2d02f8047eb0a4ceb2212a2b0f 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS17440 da931a2d02f8047eb0a4ceb2212a2b0f 529 Gene3D G3DSA:3.40.50.980 171 322 5.2E-26 T 06-07-2017 LK06_RS17440 da931a2d02f8047eb0a4ceb2212a2b0f 529 Gene3D G3DSA:2.30.38.10 329 405 2.0E-11 T 06-07-2017 LK06_RS17440 da931a2d02f8047eb0a4ceb2212a2b0f 529 Gene3D G3DSA:3.30.300.30 425 509 4.2E-6 T 06-07-2017 LK06_RS17440 da931a2d02f8047eb0a4ceb2212a2b0f 529 SUPERFAMILY SSF56801 7 513 2.75E-77 T 06-07-2017 LK06_RS17440 da931a2d02f8047eb0a4ceb2212a2b0f 529 Gene3D G3DSA:3.40.50.980 7 170 2.5E-18 T 06-07-2017 LK06_RS17440 da931a2d02f8047eb0a4ceb2212a2b0f 529 Pfam PF00501 AMP-binding enzyme 8 407 1.3E-56 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS08590 5efc86fdc582931e219cb32ad859edbc 593 Pfam PF00005 ABC transporter 20 170 5.8E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS08590 5efc86fdc582931e219cb32ad859edbc 593 Pfam PF00005 ABC transporter 362 503 3.2E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS08590 5efc86fdc582931e219cb32ad859edbc 593 SMART SM00382 28 219 2.7E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS08590 5efc86fdc582931e219cb32ad859edbc 593 SMART SM00382 371 551 1.6E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS08590 5efc86fdc582931e219cb32ad859edbc 593 SUPERFAMILY SSF52540 2 232 1.2E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08590 5efc86fdc582931e219cb32ad859edbc 593 Gene3D G3DSA:3.40.50.300 348 563 9.3E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08590 5efc86fdc582931e219cb32ad859edbc 593 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS08590 5efc86fdc582931e219cb32ad859edbc 593 Gene3D G3DSA:3.40.50.300 2 232 1.0E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08590 5efc86fdc582931e219cb32ad859edbc 593 SUPERFAMILY SSF52540 334 563 3.49E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03760 b5c68040b3724986f90fb18f7e646f34 953 SMART SM00387 516 626 0.0025 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS03760 b5c68040b3724986f90fb18f7e646f34 953 SUPERFAMILY SSF55874 503 624 1.31E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS03760 b5c68040b3724986f90fb18f7e646f34 953 Pfam PF08376 Nitrate and nitrite sensing 59 297 2.8E-35 T 06-07-2017 IPR013587 Nitrate/nitrite sensing protein LK06_RS03760 b5c68040b3724986f90fb18f7e646f34 953 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 520 624 5.6E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS03760 b5c68040b3724986f90fb18f7e646f34 953 Pfam PF00672 HAMP domain 316 400 1.1E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS03760 b5c68040b3724986f90fb18f7e646f34 953 Gene3D G3DSA:3.30.565.10 484 624 7.4E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS07230 f904b78e1251ddee433b8ef304c9fd40 528 Pfam PF00999 Sodium/hydrogen exchanger family 9 405 1.1E-54 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 LK06_RS07230 f904b78e1251ddee433b8ef304c9fd40 528 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 525 1.5E-102 T 06-07-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 LK06_RS21760 e2a788881d4b5ed3005a1d79840c0401 145 Pfam PF00293 NUDIX domain 18 125 1.0E-16 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS21760 e2a788881d4b5ed3005a1d79840c0401 145 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS21760 e2a788881d4b5ed3005a1d79840c0401 145 Gene3D G3DSA:3.90.79.10 5 135 3.1E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS21760 e2a788881d4b5ed3005a1d79840c0401 145 SUPERFAMILY SSF55811 6 139 3.93E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS21760 e2a788881d4b5ed3005a1d79840c0401 145 PRINTS PR00502 NUDIX hydrolase family signature 45 59 2.3E-8 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS21760 e2a788881d4b5ed3005a1d79840c0401 145 PRINTS PR00502 NUDIX hydrolase family signature 59 74 2.3E-8 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS25580 06825ce145165439bbf27221f638a697 217 Pfam PF00589 Phage integrase family 24 189 9.5E-8 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS25580 06825ce145165439bbf27221f638a697 217 SUPERFAMILY SSF56349 24 192 1.5E-17 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS25580 06825ce145165439bbf27221f638a697 217 Gene3D G3DSA:1.10.443.10 24 191 1.7E-16 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS27910 a7e11f2265315f191f8c6a98622ece23 404 Pfam PF00999 Sodium/hydrogen exchanger family 8 379 1.1E-50 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 LK06_RS28630 14d1f65ce9fd203f7503c241fd5a4aa4 248 Pfam PF13411 MerR HTH family regulatory protein 15 82 4.3E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS28630 14d1f65ce9fd203f7503c241fd5a4aa4 248 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 26 39 2.6E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS28630 14d1f65ce9fd203f7503c241fd5a4aa4 248 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 26 2.6E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS28630 14d1f65ce9fd203f7503c241fd5a4aa4 248 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 50 70 2.6E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS28630 14d1f65ce9fd203f7503c241fd5a4aa4 248 SMART SM00422 14 83 1.3E-22 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS28630 14d1f65ce9fd203f7503c241fd5a4aa4 248 SUPERFAMILY SSF46955 14 85 1.61E-17 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS28630 14d1f65ce9fd203f7503c241fd5a4aa4 248 Gene3D G3DSA:1.10.1660.10 14 86 5.5E-19 T 06-07-2017 LK06_RS30635 35c5bdbf555dfd8d5cc366975fd3640e 381 SUPERFAMILY SSF56112 91 318 8.35E-24 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS30635 35c5bdbf555dfd8d5cc366975fd3640e 381 Gene3D G3DSA:3.90.1200.10 180 293 2.1E-12 T 06-07-2017 LK06_RS30635 35c5bdbf555dfd8d5cc366975fd3640e 381 Pfam PF01636 Phosphotransferase enzyme family 97 296 1.3E-16 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS06415 8094e46e0f039f72efde8bb4278aa265 608 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 307 599 6.2E-13 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS06415 8094e46e0f039f72efde8bb4278aa265 608 Gene3D G3DSA:3.60.10.10 304 606 1.2E-36 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS06415 8094e46e0f039f72efde8bb4278aa265 608 SUPERFAMILY SSF56219 305 606 2.04E-30 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase LK06_RS23215 c97de78e7df53d03bb97c41503cacbe0 352 SUPERFAMILY SSF53686 4 328 1.57E-101 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS23215 c97de78e7df53d03bb97c41503cacbe0 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 319 2.1E-73 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS23215 c97de78e7df53d03bb97c41503cacbe0 352 TIGRFAM TIGR00260 thrC: threonine synthase 9 326 3.6E-96 T 06-07-2017 IPR004450 Threonine synthase-like LK06_RS23215 c97de78e7df53d03bb97c41503cacbe0 352 Gene3D G3DSA:3.40.50.1100 61 145 5.3E-42 T 06-07-2017 LK06_RS23215 c97de78e7df53d03bb97c41503cacbe0 352 Gene3D G3DSA:3.40.50.1100 146 327 5.6E-48 T 06-07-2017 LK06_RS23215 c97de78e7df53d03bb97c41503cacbe0 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 LK06_RS23215 c97de78e7df53d03bb97c41503cacbe0 352 PIRSF PIRSF038945 1 351 3.7E-166 T 06-07-2017 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 LK06_RS28745 5ec90f329aafde3289f2b84d82b68926 213 SUPERFAMILY SSF53167 8 177 7.33E-22 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS28745 5ec90f329aafde3289f2b84d82b68926 213 Gene3D G3DSA:3.40.50.1580 32 177 1.3E-18 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS28745 5ec90f329aafde3289f2b84d82b68926 213 Pfam PF01048 Phosphorylase superfamily 31 173 2.3E-13 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS04710 ea4fbe238bf1bde338c758de4b72f308 342 SUPERFAMILY SSF55347 146 310 3.4E-47 T 06-07-2017 LK06_RS04710 ea4fbe238bf1bde338c758de4b72f308 342 Gene3D G3DSA:3.40.50.720 2 154 1.8E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS04710 ea4fbe238bf1bde338c758de4b72f308 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 313 1.4E-23 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS04710 ea4fbe238bf1bde338c758de4b72f308 342 SMART SM00859 4 136 2.5E-39 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LK06_RS04710 ea4fbe238bf1bde338c758de4b72f308 342 Gene3D G3DSA:3.30.360.10 155 310 1.9E-58 T 06-07-2017 LK06_RS04710 ea4fbe238bf1bde338c758de4b72f308 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 129 1.8E-23 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LK06_RS04710 ea4fbe238bf1bde338c758de4b72f308 342 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 06-07-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS04710 ea4fbe238bf1bde338c758de4b72f308 342 SUPERFAMILY SSF51735 4 170 2.0E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS04710 ea4fbe238bf1bde338c758de4b72f308 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 37.936 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS04710 ea4fbe238bf1bde338c758de4b72f308 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 342 2.1E-116 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LK06_RS14930 348a40453dcc03cfd186f07f26670cbc 275 SUPERFAMILY SSF103196 3 121 9.68E-18 T 06-07-2017 LK06_RS14930 348a40453dcc03cfd186f07f26670cbc 275 SMART SM00960 148 241 2.2E-12 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS14930 348a40453dcc03cfd186f07f26670cbc 275 SMART SM00960 1 92 4.3E-7 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS14930 348a40453dcc03cfd186f07f26670cbc 275 Gene3D G3DSA:3.30.450.30 151 263 1.8E-9 T 06-07-2017 LK06_RS14930 348a40453dcc03cfd186f07f26670cbc 275 Gene3D G3DSA:3.30.450.30 6 119 1.8E-12 T 06-07-2017 LK06_RS14930 348a40453dcc03cfd186f07f26670cbc 275 SUPERFAMILY SSF103196 151 263 3.4E-14 T 06-07-2017 LK06_RS14930 348a40453dcc03cfd186f07f26670cbc 275 Pfam PF03259 Roadblock/LC7 domain 6 90 2.0E-9 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS14930 348a40453dcc03cfd186f07f26670cbc 275 Pfam PF03259 Roadblock/LC7 domain 155 239 6.3E-15 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS24000 8c2d28cee4c93b81e4d96ae8ea342f0c 398 Gene3D G3DSA:1.10.10.60 340 372 3.3E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS24000 8c2d28cee4c93b81e4d96ae8ea342f0c 398 Pfam PF13556 PucR C-terminal helix-turn-helix domain 337 394 2.0E-22 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS14190 1bc19334691cbc0eb12ba2932efec186 308 SUPERFAMILY SSF56300 41 301 6.69E-24 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS14190 1bc19334691cbc0eb12ba2932efec186 308 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 48 239 3.6E-6 T 06-07-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 LK06_RS14190 1bc19334691cbc0eb12ba2932efec186 308 Gene3D G3DSA:3.60.21.10 149 253 3.9E-12 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS14190 1bc19334691cbc0eb12ba2932efec186 308 Gene3D G3DSA:3.60.21.10 46 116 3.9E-12 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS06710 b297e100fa25a0072ba4512123d7a283 292 Pfam PF03707 Bacterial signalling protein N terminal repeat 182 210 7.6E-5 T 06-07-2017 IPR005330 MHYT domain LK06_RS06710 b297e100fa25a0072ba4512123d7a283 292 Pfam PF03707 Bacterial signalling protein N terminal repeat 56 106 1.9E-10 T 06-07-2017 IPR005330 MHYT domain LK06_RS06710 b297e100fa25a0072ba4512123d7a283 292 Pfam PF03707 Bacterial signalling protein N terminal repeat 120 170 6.2E-15 T 06-07-2017 IPR005330 MHYT domain LK06_RS11650 74719a4f282cc56a7658880e2c08941d 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 120 4.5E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS11650 74719a4f282cc56a7658880e2c08941d 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 84 4.5E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS11650 74719a4f282cc56a7658880e2c08941d 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 100 4.5E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS11650 74719a4f282cc56a7658880e2c08941d 168 SMART SM00347 44 142 2.2E-25 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS11650 74719a4f282cc56a7658880e2c08941d 168 Gene3D G3DSA:1.10.10.10 21 157 1.5E-42 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11650 74719a4f282cc56a7658880e2c08941d 168 SUPERFAMILY SSF46785 16 157 4.74E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11650 74719a4f282cc56a7658880e2c08941d 168 Pfam PF01047 MarR family 51 109 6.3E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS30475 3967df460158a32152a6bf3caca765c3 136 Pfam PF03610 PTS system fructose IIA component 8 123 5.7E-25 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 LK06_RS30475 3967df460158a32152a6bf3caca765c3 136 SUPERFAMILY SSF53062 7 133 4.32E-27 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 LK06_RS30475 3967df460158a32152a6bf3caca765c3 136 Gene3D G3DSA:3.40.50.510 5 135 1.4E-40 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 LK06_RS19530 e1adbf4b63bcb4e1b7ab306e03e378f3 629 SUPERFAMILY SSF53474 35 233 1.14E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS19530 e1adbf4b63bcb4e1b7ab306e03e378f3 629 Gene3D G3DSA:3.40.50.1820 28 251 1.9E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS19530 e1adbf4b63bcb4e1b7ab306e03e378f3 629 Pfam PF01083 Cutinase 102 230 7.6E-18 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 LK06_RS19530 e1adbf4b63bcb4e1b7ab306e03e378f3 629 SMART SM01110 30 260 2.8E-12 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 LK06_RS14585 cc360d50ec0ea031c97654c3d0509072 50 Gene3D G3DSA:1.10.10.10 1 46 6.5E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14585 cc360d50ec0ea031c97654c3d0509072 50 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1 28 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14585 cc360d50ec0ea031c97654c3d0509072 50 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1 17 3.0E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14585 cc360d50ec0ea031c97654c3d0509072 50 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 17 29 3.0E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14585 cc360d50ec0ea031c97654c3d0509072 50 Pfam PF00196 Bacterial regulatory proteins, luxR family 1 41 4.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS14585 cc360d50ec0ea031c97654c3d0509072 50 SUPERFAMILY SSF46894 1 47 2.82E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS14585 cc360d50ec0ea031c97654c3d0509072 50 SMART SM00421 1 41 5.9E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS04000 05e66f61430368bb39ad9a74176e5fe1 791 Gene3D G3DSA:3.30.565.10 489 629 2.3E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04000 05e66f61430368bb39ad9a74176e5fe1 791 Pfam PF00672 HAMP domain 319 405 1.1E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 LK06_RS04000 05e66f61430368bb39ad9a74176e5fe1 791 SMART SM00387 522 632 2.2E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04000 05e66f61430368bb39ad9a74176e5fe1 791 SUPERFAMILY SSF55874 490 629 1.51E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04000 05e66f61430368bb39ad9a74176e5fe1 791 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 527 630 1.5E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04000 05e66f61430368bb39ad9a74176e5fe1 791 Pfam PF08376 Nitrate and nitrite sensing 63 299 1.1E-24 T 06-07-2017 IPR013587 Nitrate/nitrite sensing protein LK06_RS19120 bbf17d5fb1ace78b158f42ccde6f228d 463 Pfam PF05147 Lanthionine synthetase C-like protein 48 227 4.1E-18 T 06-07-2017 IPR007822 Lanthionine synthetase C-like LK06_RS19120 bbf17d5fb1ace78b158f42ccde6f228d 463 Pfam PF05147 Lanthionine synthetase C-like protein 261 342 1.0E-11 T 06-07-2017 IPR007822 Lanthionine synthetase C-like LK06_RS19120 bbf17d5fb1ace78b158f42ccde6f228d 463 SUPERFAMILY SSF158745 44 398 4.58E-32 T 06-07-2017 LK06_RS19120 bbf17d5fb1ace78b158f42ccde6f228d 463 PRINTS PR01950 LanC-like protein superfamily signature 263 283 2.9E-8 T 06-07-2017 IPR007822 Lanthionine synthetase C-like LK06_RS19120 bbf17d5fb1ace78b158f42ccde6f228d 463 PRINTS PR01950 LanC-like protein superfamily signature 95 113 2.9E-8 T 06-07-2017 IPR007822 Lanthionine synthetase C-like LK06_RS19120 bbf17d5fb1ace78b158f42ccde6f228d 463 PRINTS PR01950 LanC-like protein superfamily signature 145 160 2.9E-8 T 06-07-2017 IPR007822 Lanthionine synthetase C-like LK06_RS19120 bbf17d5fb1ace78b158f42ccde6f228d 463 PRINTS PR01950 LanC-like protein superfamily signature 197 213 2.9E-8 T 06-07-2017 IPR007822 Lanthionine synthetase C-like LK06_RS19120 bbf17d5fb1ace78b158f42ccde6f228d 463 SMART SM01260 46 409 4.5E-16 T 06-07-2017 IPR007822 Lanthionine synthetase C-like LK06_RS05455 afffb374e735eedc1f7319794b8443e0 331 Gene3D G3DSA:3.90.550.10 5 225 7.2E-33 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS05455 afffb374e735eedc1f7319794b8443e0 331 SUPERFAMILY SSF53448 4 230 1.5E-39 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS05455 afffb374e735eedc1f7319794b8443e0 331 Pfam PF00535 Glycosyl transferase family 2 7 170 1.7E-21 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS06315 9b6c553231cf5fac4f2028a4e8db9ed1 277 SUPERFAMILY SSF161098 65 259 3.14E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06315 9b6c553231cf5fac4f2028a4e8db9ed1 277 Gene3D G3DSA:1.10.3720.10 67 270 6.7E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06315 9b6c553231cf5fac4f2028a4e8db9ed1 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 272 4.0E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06315 9b6c553231cf5fac4f2028a4e8db9ed1 277 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 66 164 8.7E-17 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 LK06_RS09915 7af7550a1f26a3ce1c52f1a1ba5438fb 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 190 38.184 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09915 7af7550a1f26a3ce1c52f1a1ba5438fb 201 PRINTS PR00127 Clp protease catalytic subunit P signature 165 184 2.5E-46 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09915 7af7550a1f26a3ce1c52f1a1ba5438fb 201 PRINTS PR00127 Clp protease catalytic subunit P signature 56 76 2.5E-46 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09915 7af7550a1f26a3ce1c52f1a1ba5438fb 201 PRINTS PR00127 Clp protease catalytic subunit P signature 87 104 2.5E-46 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09915 7af7550a1f26a3ce1c52f1a1ba5438fb 201 PRINTS PR00127 Clp protease catalytic subunit P signature 17 32 2.5E-46 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09915 7af7550a1f26a3ce1c52f1a1ba5438fb 201 PRINTS PR00127 Clp protease catalytic subunit P signature 108 127 2.5E-46 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LK06_RS09915 7af7550a1f26a3ce1c52f1a1ba5438fb 201 Gene3D G3DSA:3.90.226.10 17 189 1.6E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS09915 7af7550a1f26a3ce1c52f1a1ba5438fb 201 Pfam PF00574 Clp protease 16 189 2.0E-75 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA LK06_RS09915 7af7550a1f26a3ce1c52f1a1ba5438fb 201 SUPERFAMILY SSF52096 18 189 2.92E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS22435 84c087a94e73dcbc34ac5d7a881d944b 536 Pfam PF00474 Sodium:solute symporter family 44 408 1.1E-19 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS01660 95c502a5b41af7af6fdc73039754fdd2 384 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 46 293 7.3E-63 T 06-07-2017 IPR019079 Capsule synthesis protein, CapA LK06_RS01660 95c502a5b41af7af6fdc73039754fdd2 384 Gene3D G3DSA:3.60.21.30 84 289 2.4E-16 T 06-07-2017 LK06_RS01660 95c502a5b41af7af6fdc73039754fdd2 384 SMART SM00854 46 295 8.9E-73 T 06-07-2017 IPR019079 Capsule synthesis protein, CapA LK06_RS01660 95c502a5b41af7af6fdc73039754fdd2 384 SUPERFAMILY SSF56300 46 352 8.54E-34 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS11245 aab60c9a4288e7146d9e67048112fc88 105 SUPERFAMILY SSF54736 26 101 2.46E-25 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like LK06_RS11245 aab60c9a4288e7146d9e67048112fc88 105 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 29 98 3.0E-22 T 06-07-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 LK06_RS11245 aab60c9a4288e7146d9e67048112fc88 105 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 14 104 17.613 T 06-07-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS LK06_RS11245 aab60c9a4288e7146d9e67048112fc88 105 Gene3D G3DSA:3.30.1390.10 14 103 2.0E-29 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like LK06_RS05045 a3f6b74714beea34e67b83754924c80a 100 PRINTS PR00352 3Fe-4S ferredoxin signature 17 28 8.3E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS05045 a3f6b74714beea34e67b83754924c80a 100 PRINTS PR00352 3Fe-4S ferredoxin signature 28 38 8.3E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS05045 a3f6b74714beea34e67b83754924c80a 100 PRINTS PR00352 3Fe-4S ferredoxin signature 71 83 8.3E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS05045 a3f6b74714beea34e67b83754924c80a 100 Pfam PF13459 4Fe-4S single cluster domain 15 85 5.9E-18 T 06-07-2017 LK06_RS05045 a3f6b74714beea34e67b83754924c80a 100 Gene3D G3DSA:3.30.70.20 13 96 9.7E-26 T 06-07-2017 LK06_RS05045 a3f6b74714beea34e67b83754924c80a 100 SUPERFAMILY SSF54862 14 85 2.68E-9 T 06-07-2017 LK06_RS07710 d135fd08d5e184901944ac266544f9e4 418 Pfam PF07730 Histidine kinase 194 259 9.1E-19 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS07710 d135fd08d5e184901944ac266544f9e4 418 Gene3D G3DSA:3.30.565.10 309 397 5.0E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS07710 d135fd08d5e184901944ac266544f9e4 418 SUPERFAMILY SSF55874 276 394 2.26E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04315 079f5f76516f4688e63d62f499bdd03b 180 Gene3D G3DSA:1.20.1440.20 19 139 2.0E-6 T 06-07-2017 IPR023353 LemA-like domain LK06_RS04315 079f5f76516f4688e63d62f499bdd03b 180 SUPERFAMILY SSF140478 27 139 4.45E-5 T 06-07-2017 IPR023353 LemA-like domain LK06_RS04315 079f5f76516f4688e63d62f499bdd03b 180 Pfam PF04011 LemA family 8 139 5.9E-5 T 06-07-2017 IPR007156 LemA LK06_RS05300 da3008fd4fa37501e2bbf56866b10d8d 256 SUPERFAMILY SSF51735 9 248 1.61E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05300 da3008fd4fa37501e2bbf56866b10d8d 256 Pfam PF00106 short chain dehydrogenase 9 187 3.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05300 da3008fd4fa37501e2bbf56866b10d8d 256 Gene3D G3DSA:3.40.50.720 9 218 1.7E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05300 da3008fd4fa37501e2bbf56866b10d8d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05300 da3008fd4fa37501e2bbf56866b10d8d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05300 da3008fd4fa37501e2bbf56866b10d8d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05300 da3008fd4fa37501e2bbf56866b10d8d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05300 da3008fd4fa37501e2bbf56866b10d8d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS05300 da3008fd4fa37501e2bbf56866b10d8d 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS03985 16536a1cc89cc1b5e0dd3c708e2ca63c 262 SUPERFAMILY SSF56317 1 261 1.7E-70 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS03985 16536a1cc89cc1b5e0dd3c708e2ca63c 262 Pfam PF00795 Carbon-nitrogen hydrolase 4 242 2.2E-46 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS03985 16536a1cc89cc1b5e0dd3c708e2ca63c 262 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 140 160 - T 06-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site LK06_RS03985 16536a1cc89cc1b5e0dd3c708e2ca63c 262 Gene3D G3DSA:3.60.110.10 1 261 4.6E-73 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS15840 561aa99609dd82d687e61e396263d7c6 373 ProSitePatterns PS00618 RecF protein signature 2. 316 334 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 LK06_RS15840 561aa99609dd82d687e61e396263d7c6 373 SUPERFAMILY SSF52540 1 347 8.38E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15840 561aa99609dd82d687e61e396263d7c6 373 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 LK06_RS15840 561aa99609dd82d687e61e396263d7c6 373 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 373 97.97 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 LK06_RS15840 561aa99609dd82d687e61e396263d7c6 373 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 363 9.9E-128 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 LK06_RS15840 561aa99609dd82d687e61e396263d7c6 373 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 349 4.0E-18 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal LK06_RS15840 561aa99609dd82d687e61e396263d7c6 373 Gene3D G3DSA:3.40.50.300 1 166 4.4E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15840 561aa99609dd82d687e61e396263d7c6 373 Gene3D G3DSA:3.40.50.300 244 348 4.4E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03955 612e19eea589c98dc06b934b75bebc83 201 Gene3D G3DSA:2.40.30.20 5 103 1.1E-33 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 LK06_RS03955 612e19eea589c98dc06b934b75bebc83 201 Gene3D G3DSA:2.40.30.20 104 194 4.9E-31 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 LK06_RS03955 612e19eea589c98dc06b934b75bebc83 201 SUPERFAMILY SSF63380 2 87 4.85E-24 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS03955 612e19eea589c98dc06b934b75bebc83 201 SUPERFAMILY SSF63380 92 194 1.7E-33 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS03955 612e19eea589c98dc06b934b75bebc83 201 PIRSF PIRSF000498 1 201 9.4E-71 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS03955 612e19eea589c98dc06b934b75bebc83 201 Pfam PF00677 Lumazine binding domain 3 85 3.0E-23 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS03955 612e19eea589c98dc06b934b75bebc83 201 Pfam PF00677 Lumazine binding domain 99 183 2.4E-23 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS03955 612e19eea589c98dc06b934b75bebc83 201 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 195 1.9E-63 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LK06_RS22295 af51e77ebb27a9a094c30f84518cb975 152 SUPERFAMILY SSF54690 20 151 6.02E-41 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS22295 af51e77ebb27a9a094c30f84518cb975 152 Gene3D G3DSA:3.90.1170.40 14 151 4.6E-47 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS22295 af51e77ebb27a9a094c30f84518cb975 152 Pfam PF02391 MoaE protein 23 133 1.7E-35 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LK06_RS05435 51f0fbaea223bbdf30e5f3e68b65d9e9 544 SUPERFAMILY SSF56112 9 305 2.4E-69 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS05435 51f0fbaea223bbdf30e5f3e68b65d9e9 544 Pfam PF00069 Protein kinase domain 15 265 2.4E-44 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS05435 51f0fbaea223bbdf30e5f3e68b65d9e9 544 SMART SM00220 15 272 1.5E-61 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS05435 51f0fbaea223bbdf30e5f3e68b65d9e9 544 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS05435 51f0fbaea223bbdf30e5f3e68b65d9e9 544 Gene3D G3DSA:3.30.200.20 9 85 5.4E-21 T 06-07-2017 LK06_RS05435 51f0fbaea223bbdf30e5f3e68b65d9e9 544 Gene3D G3DSA:1.10.510.10 86 266 8.3E-48 T 06-07-2017 LK06_RS05435 51f0fbaea223bbdf30e5f3e68b65d9e9 544 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 LK06_RS28735 064c9bd5da9b026eb96d9605c6374983 377 SUPERFAMILY SSF48576 54 376 9.92E-74 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS28735 064c9bd5da9b026eb96d9605c6374983 377 Gene3D G3DSA:1.10.600.10 74 376 1.7E-79 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS28735 064c9bd5da9b026eb96d9605c6374983 377 Pfam PF00348 Polyprenyl synthetase 85 310 3.3E-51 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS28735 064c9bd5da9b026eb96d9605c6374983 377 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 124 138 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS09000 44a4b1c2b4fcd3c1cf36ec5d01ae4421 514 Gene3D G3DSA:3.30.420.190 253 449 8.9E-10 T 06-07-2017 LK06_RS09000 44a4b1c2b4fcd3c1cf36ec5d01ae4421 514 Gene3D G3DSA:3.30.420.40 2 68 6.1E-5 T 06-07-2017 LK06_RS09000 44a4b1c2b4fcd3c1cf36ec5d01ae4421 514 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 2 171 1.2E-36 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LK06_RS09000 44a4b1c2b4fcd3c1cf36ec5d01ae4421 514 Pfam PF01968 Hydantoinase/oxoprolinase 191 394 8.1E-32 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LK06_RS09000 44a4b1c2b4fcd3c1cf36ec5d01ae4421 514 SUPERFAMILY SSF53067 358 440 1.3E-22 T 06-07-2017 LK06_RS09000 44a4b1c2b4fcd3c1cf36ec5d01ae4421 514 SUPERFAMILY SSF53067 249 329 1.3E-22 T 06-07-2017 LK06_RS09000 44a4b1c2b4fcd3c1cf36ec5d01ae4421 514 SUPERFAMILY SSF53067 2 75 1.3E-22 T 06-07-2017 LK06_RS06450 ab14dea4159d3daeba996433bf269bdd 110 SUPERFAMILY SSF117916 10 104 2.16E-27 T 06-07-2017 LK06_RS06450 ab14dea4159d3daeba996433bf269bdd 110 Pfam PF01883 Domain of unknown function DUF59 12 72 1.9E-18 T 06-07-2017 IPR002744 Domain of unknown function DUF59 LK06_RS23420 fc007d4bcc6332dc0f5ab4e2a9c7e831 311 Gene3D G3DSA:1.20.1170.10 25 126 7.9E-4 T 06-07-2017 LK06_RS29190 0327991df9a8db9b3a7e1e3ac73afbdf 565 SUPERFAMILY SSF56801 43 559 3.01E-113 T 06-07-2017 LK06_RS29190 0327991df9a8db9b3a7e1e3ac73afbdf 565 Gene3D G3DSA:2.30.38.10 371 456 5.5E-16 T 06-07-2017 LK06_RS29190 0327991df9a8db9b3a7e1e3ac73afbdf 565 Gene3D G3DSA:3.40.50.980 52 206 3.7E-30 T 06-07-2017 LK06_RS29190 0327991df9a8db9b3a7e1e3ac73afbdf 565 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 70 491 6.3E-98 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS29190 0327991df9a8db9b3a7e1e3ac73afbdf 565 Pfam PF00501 AMP-binding enzyme 52 467 1.5E-73 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS29190 0327991df9a8db9b3a7e1e3ac73afbdf 565 Pfam PF13193 AMP-binding enzyme C-terminal domain 475 547 2.9E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS29190 0327991df9a8db9b3a7e1e3ac73afbdf 565 Gene3D G3DSA:3.40.50.980 207 362 2.1E-36 T 06-07-2017 LK06_RS29190 0327991df9a8db9b3a7e1e3ac73afbdf 565 Gene3D G3DSA:3.30.300.30 461 559 2.2E-26 T 06-07-2017 LK06_RS10160 42db62690e8e57385ab295ac56f4799c 430 SMART SM00332 155 418 3.7E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS10160 42db62690e8e57385ab295ac56f4799c 430 SUPERFAMILY SSF81606 165 420 1.57E-38 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS10160 42db62690e8e57385ab295ac56f4799c 430 Pfam PF13672 Protein phosphatase 2C 177 382 9.3E-13 T 06-07-2017 LK06_RS10160 42db62690e8e57385ab295ac56f4799c 430 Gene3D G3DSA:3.60.40.10 165 419 2.8E-48 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS10160 42db62690e8e57385ab295ac56f4799c 430 Pfam PF13248 zinc-ribbon domain 11 34 1.7E-6 T 06-07-2017 LK06_RS08195 abadbec23cbf2fc59c58e31e1475f746 394 SMART SM00530 11 68 4.9E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS08195 abadbec23cbf2fc59c58e31e1475f746 394 Pfam PF13560 Helix-turn-helix domain 20 68 1.5E-11 T 06-07-2017 LK06_RS08195 abadbec23cbf2fc59c58e31e1475f746 394 SUPERFAMILY SSF47413 9 70 1.52E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS08195 abadbec23cbf2fc59c58e31e1475f746 394 Gene3D G3DSA:1.10.260.40 8 76 9.0E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS13225 740ffbf57d5cc3f1472ceeea2bdee0bd 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 2.4E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13225 740ffbf57d5cc3f1472ceeea2bdee0bd 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 2.4E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13225 740ffbf57d5cc3f1472ceeea2bdee0bd 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 2.4E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13225 740ffbf57d5cc3f1472ceeea2bdee0bd 124 Gene3D G3DSA:1.10.10.10 18 117 2.6E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13225 740ffbf57d5cc3f1472ceeea2bdee0bd 124 SUPERFAMILY SSF46785 24 115 1.15E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13225 740ffbf57d5cc3f1472ceeea2bdee0bd 124 SMART SM00418 39 118 3.5E-32 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13225 740ffbf57d5cc3f1472ceeea2bdee0bd 124 Pfam PF01022 Bacterial regulatory protein, arsR family 46 94 3.1E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS04180 590e5ba639b40076e17cd006c231def7 275 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 9 91 1.7E-25 T 06-07-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 LK06_RS04180 590e5ba639b40076e17cd006c231def7 275 SUPERFAMILY SSF53223 6 104 1.5E-27 T 06-07-2017 LK06_RS04180 590e5ba639b40076e17cd006c231def7 275 Gene3D G3DSA:3.40.50.720 111 272 2.9E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS04180 590e5ba639b40076e17cd006c231def7 275 Gene3D G3DSA:3.40.192.10 5 110 7.3E-39 T 06-07-2017 LK06_RS04180 590e5ba639b40076e17cd006c231def7 275 SUPERFAMILY SSF51735 105 267 2.67E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS04180 590e5ba639b40076e17cd006c231def7 275 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 124 197 1.6E-4 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LK06_RS21305 cd6a4c3491dfdcd7aa27af559f649028 198 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 11 57 2.8E-7 T 06-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal LK06_RS00405 81e9a1fa05c0aca66ce6fa8ea7d6033f 614 Pfam PF00501 AMP-binding enzyme 71 496 1.8E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS00405 81e9a1fa05c0aca66ce6fa8ea7d6033f 614 Gene3D G3DSA:3.40.50.980 233 395 6.2E-31 T 06-07-2017 LK06_RS00405 81e9a1fa05c0aca66ce6fa8ea7d6033f 614 Gene3D G3DSA:3.30.300.30 491 593 8.6E-26 T 06-07-2017 LK06_RS00405 81e9a1fa05c0aca66ce6fa8ea7d6033f 614 Pfam PF13193 AMP-binding enzyme C-terminal domain 505 583 3.5E-20 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS00405 81e9a1fa05c0aca66ce6fa8ea7d6033f 614 SUPERFAMILY SSF56801 45 596 3.14E-149 T 06-07-2017 LK06_RS00405 81e9a1fa05c0aca66ce6fa8ea7d6033f 614 Gene3D G3DSA:2.30.38.10 400 489 7.1E-19 T 06-07-2017 LK06_RS00405 81e9a1fa05c0aca66ce6fa8ea7d6033f 614 Gene3D G3DSA:3.40.50.980 71 232 1.5E-30 T 06-07-2017 LK06_RS00405 81e9a1fa05c0aca66ce6fa8ea7d6033f 614 ProSitePatterns PS00455 Putative AMP-binding domain signature. 228 239 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS29780 4b93e44bfe4a3573da95b1b163cccaa8 271 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 226 238 6.9E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS29780 4b93e44bfe4a3573da95b1b163cccaa8 271 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 210 6.9E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS29780 4b93e44bfe4a3573da95b1b163cccaa8 271 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 210 226 6.9E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS29780 4b93e44bfe4a3573da95b1b163cccaa8 271 SMART SM00421 193 250 1.9E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS29780 4b93e44bfe4a3573da95b1b163cccaa8 271 Gene3D G3DSA:1.10.10.10 186 255 2.7E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29780 4b93e44bfe4a3573da95b1b163cccaa8 271 Pfam PF00196 Bacterial regulatory proteins, luxR family 195 247 9.2E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS29780 4b93e44bfe4a3573da95b1b163cccaa8 271 SUPERFAMILY SSF46894 188 256 1.39E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS04015 fc21a27a723abd33c0174e535b94445c 274 SUPERFAMILY SSF161098 9 260 1.44E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS04015 fc21a27a723abd33c0174e535b94445c 274 Gene3D G3DSA:1.10.3720.10 13 267 1.2E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS04015 fc21a27a723abd33c0174e535b94445c 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 261 4.6E-8 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS17525 1d8b9684743e34756d70b3f911501c11 206 Pfam PF01865 Protein of unknown function DUF47 7 203 1.6E-28 T 06-07-2017 IPR018445 Putative phosphate transport regulator LK06_RS17205 d11533a4cc024d5080e6ba29520aa5aa 375 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 97 214 6.3E-22 T 06-07-2017 LK06_RS17205 d11533a4cc024d5080e6ba29520aa5aa 375 TIGRFAM TIGR04188 methyltr_grsp: methyltransferase, ATP-grasp peptide maturase system 11 370 1.3E-144 T 06-07-2017 IPR026448 Methyltransferase, ATP-grasp peptide maturase system LK06_RS17205 d11533a4cc024d5080e6ba29520aa5aa 375 Gene3D G3DSA:3.40.50.150 13 258 9.3E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS17205 d11533a4cc024d5080e6ba29520aa5aa 375 SUPERFAMILY SSF53335 106 218 1.63E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS17205 d11533a4cc024d5080e6ba29520aa5aa 375 SUPERFAMILY SSF53335 6 59 1.63E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25380 2ca81231231973199574944ec4bff951 250 Gene3D G3DSA:2.70.70.10 94 244 3.1E-41 T 06-07-2017 LK06_RS25380 2ca81231231973199574944ec4bff951 250 SUPERFAMILY SSF51261 77 243 1.2E-42 T 06-07-2017 IPR011055 Duplicated hybrid motif LK06_RS25380 2ca81231231973199574944ec4bff951 250 Pfam PF01551 Peptidase family M23 142 239 9.3E-29 T 06-07-2017 IPR016047 Peptidase M23 LK06_RS22200 3d4654a45854ae2b3c391483cdf8af57 1133 SUPERFAMILY SSF52540 574 780 5.72E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22200 3d4654a45854ae2b3c391483cdf8af57 1133 SUPERFAMILY SSF52540 36 470 5.72E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22200 3d4654a45854ae2b3c391483cdf8af57 1133 Gene3D G3DSA:3.40.50.300 37 157 6.8E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22200 3d4654a45854ae2b3c391483cdf8af57 1133 Gene3D G3DSA:3.40.50.300 203 319 6.8E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22200 3d4654a45854ae2b3c391483cdf8af57 1133 Pfam PF13361 UvrD-like helicase C-terminal domain 635 762 2.6E-19 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 LK06_RS22200 3d4654a45854ae2b3c391483cdf8af57 1133 Gene3D G3DSA:3.40.50.300 682 781 4.5E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22200 3d4654a45854ae2b3c391483cdf8af57 1133 Gene3D G3DSA:3.40.50.300 335 454 4.5E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22200 3d4654a45854ae2b3c391483cdf8af57 1133 Pfam PF00580 UvrD/REP helicase N-terminal domain 39 316 3.2E-47 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 LK06_RS22200 3d4654a45854ae2b3c391483cdf8af57 1133 SUPERFAMILY SSF52980 895 1039 4.4E-6 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LK06_RS22200 3d4654a45854ae2b3c391483cdf8af57 1133 Pfam PF12705 PD-(D/E)XK nuclease superfamily 870 1122 5.2E-38 T 06-07-2017 LK06_RS05910 16d5fe34c72277553204b9096abea6d1 79 Pfam PF03777 Small secreted domain (DUF320) 23 78 2.2E-22 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS24025 b9ffc60ac75af65007076bfe8a9c4e39 362 ProSitePatterns PS00770 Aminotransferases class-IV signature. 238 267 - T 06-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 LK06_RS24025 b9ffc60ac75af65007076bfe8a9c4e39 362 PIRSF PIRSF006468 5 362 1.0E-133 T 06-07-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 LK06_RS24025 b9ffc60ac75af65007076bfe8a9c4e39 362 Gene3D G3DSA:3.20.10.10 180 348 1.2E-65 T 06-07-2017 LK06_RS24025 b9ffc60ac75af65007076bfe8a9c4e39 362 Pfam PF01063 Amino-transferase class IV 74 316 7.9E-34 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 LK06_RS24025 b9ffc60ac75af65007076bfe8a9c4e39 362 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 48 359 1.0E-135 T 06-07-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 LK06_RS24025 b9ffc60ac75af65007076bfe8a9c4e39 362 SUPERFAMILY SSF56752 13 359 1.44E-118 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 LK06_RS24025 b9ffc60ac75af65007076bfe8a9c4e39 362 Gene3D G3DSA:3.30.470.10 20 179 2.3E-76 T 06-07-2017 LK06_RS01175 197d8f5356a893317691b9928f369264 418 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 360 369 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 Pfam PF00067 Cytochrome P450 91 387 1.4E-26 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00385 P450 superfamily signature 358 367 1.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00385 P450 superfamily signature 367 378 1.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00385 P450 superfamily signature 257 274 1.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00385 P450 superfamily signature 292 303 1.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 SUPERFAMILY SSF48264 19 418 2.88E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 Gene3D G3DSA:1.10.630.10 19 418 1.9E-114 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00359 B-class P450 signature 147 163 1.1E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00359 B-class P450 signature 337 352 1.1E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00359 B-class P450 signature 358 367 1.1E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00359 B-class P450 signature 292 303 1.1E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00359 B-class P450 signature 164 179 1.1E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00359 B-class P450 signature 100 111 1.1E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00359 B-class P450 signature 367 378 1.1E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS01175 197d8f5356a893317691b9928f369264 418 PRINTS PR00359 B-class P450 signature 309 336 1.1E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS10965 2469db8a6b200c7db8fadfe862a44c77 250 Pfam PF09339 IclR helix-turn-helix domain 15 60 4.7E-6 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LK06_RS10965 2469db8a6b200c7db8fadfe862a44c77 250 Gene3D G3DSA:3.30.450.40 85 240 1.8E-24 T 06-07-2017 IPR029016 GAF domain-like LK06_RS10965 2469db8a6b200c7db8fadfe862a44c77 250 Pfam PF01614 Bacterial transcriptional regulator 131 232 8.3E-15 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal LK06_RS10965 2469db8a6b200c7db8fadfe862a44c77 250 SUPERFAMILY SSF55781 85 238 7.19E-22 T 06-07-2017 IPR029016 GAF domain-like LK06_RS10965 2469db8a6b200c7db8fadfe862a44c77 250 SUPERFAMILY SSF46785 11 78 4.06E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS10965 2469db8a6b200c7db8fadfe862a44c77 250 Gene3D G3DSA:1.10.10.10 10 80 2.7E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18840 fa7eefaaff2ccbfbfec4cf4b47bc01fb 202 Gene3D G3DSA:2.30.110.10 40 196 1.0E-56 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS18840 fa7eefaaff2ccbfbfec4cf4b47bc01fb 202 SUPERFAMILY SSF50475 43 198 5.89E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS18840 fa7eefaaff2ccbfbfec4cf4b47bc01fb 202 Pfam PF01613 Flavin reductase like domain 52 199 7.1E-37 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS18840 fa7eefaaff2ccbfbfec4cf4b47bc01fb 202 SMART SM00903 51 198 1.3E-54 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS06215 e0641a70adabf7272cb800679d9c69c2 256 Pfam PF01183 Glycosyl hydrolases family 25 46 232 5.9E-52 T 06-07-2017 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 LK06_RS06215 e0641a70adabf7272cb800679d9c69c2 256 Gene3D G3DSA:3.20.20.80 43 250 4.4E-72 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS06215 e0641a70adabf7272cb800679d9c69c2 256 SUPERFAMILY SSF51445 43 249 1.68E-64 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS06215 e0641a70adabf7272cb800679d9c69c2 256 SMART SM00641 42 153 7.5E-34 T 06-07-2017 IPR018077 Glycoside hydrolase, family 25 subgroup LK06_RS03965 dba8980e42669df680b1996ed092caeb 404 Gene3D G3DSA:1.20.1250.20 209 394 2.8E-12 T 06-07-2017 LK06_RS03965 dba8980e42669df680b1996ed092caeb 404 Gene3D G3DSA:1.20.1250.20 19 190 7.4E-16 T 06-07-2017 LK06_RS03965 dba8980e42669df680b1996ed092caeb 404 SUPERFAMILY SSF103473 13 383 1.44E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS03965 dba8980e42669df680b1996ed092caeb 404 Pfam PF07690 Major Facilitator Superfamily 21 236 7.6E-12 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS18720 45992ae1dbb60f26c10ac8b5332ced00 286 Pfam PF12697 Alpha/beta hydrolase family 35 274 1.8E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS18720 45992ae1dbb60f26c10ac8b5332ced00 286 Gene3D G3DSA:3.40.50.1820 6 281 2.4E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS18720 45992ae1dbb60f26c10ac8b5332ced00 286 SUPERFAMILY SSF53474 7 280 2.3E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS14000 ba01af004a49b5a9f442a54de1142d0e 506 Pfam PF05175 Methyltransferase small domain 167 284 4.7E-12 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 LK06_RS14000 ba01af004a49b5a9f442a54de1142d0e 506 Gene3D G3DSA:3.40.50.150 164 304 1.8E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS14000 ba01af004a49b5a9f442a54de1142d0e 506 SUPERFAMILY SSF53335 164 301 6.64E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS14000 ba01af004a49b5a9f442a54de1142d0e 506 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 235 241 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LK06_RS01675 047307bf0a78514e0e0fc3ba7a9217b0 218 Pfam PF13490 Putative zinc-finger 9 37 9.0E-7 T 06-07-2017 IPR027383 Putative zinc-finger LK06_RS26305 94b88248784d8aeaf7273f86ceeea19b 154 Gene3D G3DSA:3.10.180.10 13 144 3.0E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS26305 94b88248784d8aeaf7273f86ceeea19b 154 SUPERFAMILY SSF54593 12 148 4.83E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS26305 94b88248784d8aeaf7273f86ceeea19b 154 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 129 1.5E-8 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS15875 e290d1f7387fb123456b0cf1afe4b9fd 121 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 5.8E-26 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor LK06_RS15875 e290d1f7387fb123456b0cf1afe4b9fd 121 SMART SM01234 1 68 4.2E-41 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor LK06_RS15875 e290d1f7387fb123456b0cf1afe4b9fd 121 Pfam PF01809 Haemolytic domain 5 68 3.9E-27 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor LK06_RS15875 e290d1f7387fb123456b0cf1afe4b9fd 121 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.783 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor LK06_RS15875 e290d1f7387fb123456b0cf1afe4b9fd 121 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 3.0E-25 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor LK06_RS28050 f0d953c130f94bd4ce60bd5d0811ce27 655 Pfam PF00326 Prolyl oligopeptidase family 438 641 1.9E-43 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 LK06_RS28050 f0d953c130f94bd4ce60bd5d0811ce27 655 SUPERFAMILY SSF82171 92 367 1.33E-12 T 06-07-2017 LK06_RS28050 f0d953c130f94bd4ce60bd5d0811ce27 655 SUPERFAMILY SSF53474 382 633 1.5E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28050 f0d953c130f94bd4ce60bd5d0811ce27 655 Pfam PF07676 WD40-like Beta Propeller Repeat 189 202 0.14 T 06-07-2017 IPR011659 WD40-like Beta Propeller LK06_RS28050 f0d953c130f94bd4ce60bd5d0811ce27 655 Pfam PF07676 WD40-like Beta Propeller Repeat 247 267 0.18 T 06-07-2017 IPR011659 WD40-like Beta Propeller LK06_RS28050 f0d953c130f94bd4ce60bd5d0811ce27 655 Gene3D G3DSA:3.40.50.1820 156 189 3.2E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28050 f0d953c130f94bd4ce60bd5d0811ce27 655 Gene3D G3DSA:3.40.50.1820 345 634 3.2E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS28050 f0d953c130f94bd4ce60bd5d0811ce27 655 Gene3D G3DSA:2.120.10.60 190 267 9.1E-8 T 06-07-2017 LK06_RS27205 03b5fe0c6bb2b23c19010b86aece5f4a 867 Pfam PF13535 ATP-grasp domain 167 304 9.8E-14 T 06-07-2017 LK06_RS27205 03b5fe0c6bb2b23c19010b86aece5f4a 867 Pfam PF13535 ATP-grasp domain 599 744 2.9E-16 T 06-07-2017 LK06_RS27205 03b5fe0c6bb2b23c19010b86aece5f4a 867 SUPERFAMILY SSF56059 166 345 1.1E-25 T 06-07-2017 LK06_RS27205 03b5fe0c6bb2b23c19010b86aece5f4a 867 Gene3D G3DSA:3.30.470.20 554 854 6.0E-17 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS27205 03b5fe0c6bb2b23c19010b86aece5f4a 867 SUPERFAMILY SSF56059 562 770 1.77E-23 T 06-07-2017 LK06_RS27205 03b5fe0c6bb2b23c19010b86aece5f4a 867 Gene3D G3DSA:3.30.470.20 166 333 7.1E-15 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS16600 7ca856da3b7efa7009b7c470197de0d5 839 SMART SM00331 483 695 5.8E-37 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS16600 7ca856da3b7efa7009b7c470197de0d5 839 Pfam PF13185 GAF domain 316 452 8.0E-7 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS16600 7ca856da3b7efa7009b7c470197de0d5 839 Gene3D G3DSA:3.30.450.40 304 460 2.5E-11 T 06-07-2017 IPR029016 GAF domain-like LK06_RS16600 7ca856da3b7efa7009b7c470197de0d5 839 SUPERFAMILY SSF55781 106 233 2.62E-5 T 06-07-2017 IPR029016 GAF domain-like LK06_RS16600 7ca856da3b7efa7009b7c470197de0d5 839 SUPERFAMILY SSF55874 738 814 4.1E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16600 7ca856da3b7efa7009b7c470197de0d5 839 SUPERFAMILY SSF81606 498 696 7.06E-7 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS16600 7ca856da3b7efa7009b7c470197de0d5 839 SUPERFAMILY SSF55781 318 462 3.27E-11 T 06-07-2017 IPR029016 GAF domain-like LK06_RS16600 7ca856da3b7efa7009b7c470197de0d5 839 Gene3D G3DSA:3.30.565.10 718 830 5.8E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16600 7ca856da3b7efa7009b7c470197de0d5 839 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 510 695 1.1E-47 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS16600 7ca856da3b7efa7009b7c470197de0d5 839 Pfam PF13581 Histidine kinase-like ATPase domain 716 826 2.5E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS05295 545663c0595bc220fba53e65a7315a46 559 Gene3D G3DSA:2.30.38.10 375 448 1.1E-25 T 06-07-2017 LK06_RS05295 545663c0595bc220fba53e65a7315a46 559 SUPERFAMILY SSF56801 10 553 1.31E-155 T 06-07-2017 LK06_RS05295 545663c0595bc220fba53e65a7315a46 559 Pfam PF00501 AMP-binding enzyme 35 456 2.1E-99 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS05295 545663c0595bc220fba53e65a7315a46 559 Pfam PF13193 AMP-binding enzyme C-terminal domain 466 541 1.3E-21 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS05295 545663c0595bc220fba53e65a7315a46 559 ProSitePatterns PS00455 Putative AMP-binding domain signature. 206 217 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS05295 545663c0595bc220fba53e65a7315a46 559 Gene3D G3DSA:3.30.300.30 452 551 8.8E-34 T 06-07-2017 LK06_RS05295 545663c0595bc220fba53e65a7315a46 559 Gene3D G3DSA:3.40.50.980 28 210 1.5E-38 T 06-07-2017 LK06_RS05295 545663c0595bc220fba53e65a7315a46 559 Gene3D G3DSA:3.40.50.980 211 368 2.2E-38 T 06-07-2017 LK06_RS19710 b11a6c610c140073360a9a10e10f3feb 289 Pfam PF00398 Ribosomal RNA adenine dimethylase 28 283 1.1E-44 T 06-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm LK06_RS19710 b11a6c610c140073360a9a10e10f3feb 289 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 24 283 4.4E-71 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 LK06_RS19710 b11a6c610c140073360a9a10e10f3feb 289 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 24 286 48.392 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 LK06_RS19710 b11a6c610c140073360a9a10e10f3feb 289 Gene3D G3DSA:3.40.50.150 12 215 3.9E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19710 b11a6c610c140073360a9a10e10f3feb 289 Gene3D G3DSA:1.10.8.100 221 284 8.2E-22 T 06-07-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 LK06_RS19710 b11a6c610c140073360a9a10e10f3feb 289 SUPERFAMILY SSF53335 24 284 1.37E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19710 b11a6c610c140073360a9a10e10f3feb 289 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 56 83 - T 06-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 LK06_RS19710 b11a6c610c140073360a9a10e10f3feb 289 SMART SM00650 40 214 1.5E-69 T 06-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 LK06_RS02650 7c0d6be0f20c7bdbdc005c5566325d71 205 SMART SM00823 Phosphopantetheine attachment site 133 202 8.2E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS02650 7c0d6be0f20c7bdbdc005c5566325d71 205 SUPERFAMILY SSF47336 126 198 1.03E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02650 7c0d6be0f20c7bdbdc005c5566325d71 205 Gene3D G3DSA:1.10.1200.10 138 201 4.1E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02650 7c0d6be0f20c7bdbdc005c5566325d71 205 Pfam PF00550 Phosphopantetheine attachment site 135 194 9.2E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02650 7c0d6be0f20c7bdbdc005c5566325d71 205 SUPERFAMILY SSF56801 33 144 9.94E-16 T 06-07-2017 LK06_RS02650 7c0d6be0f20c7bdbdc005c5566325d71 205 Gene3D G3DSA:3.30.300.30 33 137 8.9E-17 T 06-07-2017 LK06_RS02650 7c0d6be0f20c7bdbdc005c5566325d71 205 Pfam PF13193 AMP-binding enzyme C-terminal domain 35 103 1.0E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS27670 53aff71ef300ff88c7d3f9668f32ce7a 498 Gene3D G3DSA:3.40.50.2000 266 462 7.0E-70 T 06-07-2017 LK06_RS27670 53aff71ef300ff88c7d3f9668f32ce7a 498 SUPERFAMILY SSF53756 15 478 5.27E-135 T 06-07-2017 LK06_RS27670 53aff71ef300ff88c7d3f9668f32ce7a 498 Pfam PF00982 Glycosyltransferase family 20 16 477 7.5E-144 T 06-07-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 LK06_RS27670 53aff71ef300ff88c7d3f9668f32ce7a 498 Gene3D G3DSA:3.40.50.2000 15 265 7.7E-81 T 06-07-2017 LK06_RS08050 821a5b9573174260d5348380811a6d4c 351 Gene3D G3DSA:3.40.50.720 1 247 6.9E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08050 821a5b9573174260d5348380811a6d4c 351 SUPERFAMILY SSF51735 1 282 1.97E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08050 821a5b9573174260d5348380811a6d4c 351 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 209 8.0E-8 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS13280 eaa97271cdff4d092e0a9625cdfe51bc 205 SUPERFAMILY SSF160904 18 193 2.75E-39 T 06-07-2017 LK06_RS13280 eaa97271cdff4d092e0a9625cdfe51bc 205 Pfam PF11706 CGNR zinc finger 155 194 1.3E-8 T 06-07-2017 IPR021005 Zinc finger, CGNR LK06_RS13280 eaa97271cdff4d092e0a9625cdfe51bc 205 Pfam PF07336 Putative stress-induced transcription regulator 22 150 2.7E-22 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator LK06_RS13280 eaa97271cdff4d092e0a9625cdfe51bc 205 Gene3D G3DSA:1.10.3300.10 21 194 1.4E-38 T 06-07-2017 IPR023286 ABATE domain LK06_RS21115 5471a28d990dd54b6e4e52ee4cd6bc14 331 Pfam PF06259 Alpha/beta hydrolase 96 270 3.1E-41 T 06-07-2017 IPR010427 Protein of unknown function DUF1023 LK06_RS21115 5471a28d990dd54b6e4e52ee4cd6bc14 331 SUPERFAMILY SSF53474 133 264 7.35E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21115 5471a28d990dd54b6e4e52ee4cd6bc14 331 Gene3D G3DSA:3.40.50.1820 143 244 1.3E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS17170 8a4cdc5d315a5695312cbb1819000392 409 Gene3D G3DSA:1.25.40.10 150 376 2.6E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS17170 8a4cdc5d315a5695312cbb1819000392 409 SUPERFAMILY SSF48452 150 366 4.74E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS17170 8a4cdc5d315a5695312cbb1819000392 409 SUPERFAMILY SSF47413 24 73 9.01E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS17170 8a4cdc5d315a5695312cbb1819000392 409 Gene3D G3DSA:1.10.260.40 25 73 6.3E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS04775 7de67112efd48430e353d2342d7f2bd7 178 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS04775 7de67112efd48430e353d2342d7f2bd7 178 Pfam PF00293 NUDIX domain 40 164 2.9E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS04775 7de67112efd48430e353d2342d7f2bd7 178 Gene3D G3DSA:3.90.79.10 2 174 3.2E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS04775 7de67112efd48430e353d2342d7f2bd7 178 SUPERFAMILY SSF55811 3 173 7.45E-38 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS23870 36ae19f40faf22cabaaa260d3b40e062 333 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 9 326 2.5E-16 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 LK06_RS23870 36ae19f40faf22cabaaa260d3b40e062 333 Gene3D G3DSA:3.20.20.210 79 330 3.0E-14 T 06-07-2017 LK06_RS23870 36ae19f40faf22cabaaa260d3b40e062 333 SUPERFAMILY SSF51726 54 329 1.03E-29 T 06-07-2017 LK06_RS14370 dce507b56edd138a499fc7fc5ec7e9aa 228 Pfam PF01794 Ferric reductase like transmembrane component 19 140 1.1E-9 T 06-07-2017 IPR013130 Ferric reductase transmembrane component-like domain LK06_RS18565 3b41d80e05649737c31591f349b649fa 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site LK06_RS18565 3b41d80e05649737c31591f349b649fa 145 Gene3D G3DSA:1.10.10.10 8 140 2.7E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18565 3b41d80e05649737c31591f349b649fa 145 SMART SM00347 29 129 5.5E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS18565 3b41d80e05649737c31591f349b649fa 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 5.2E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS18565 3b41d80e05649737c31591f349b649fa 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 5.2E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS18565 3b41d80e05649737c31591f349b649fa 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 5.2E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS18565 3b41d80e05649737c31591f349b649fa 145 SUPERFAMILY SSF46785 13 136 1.98E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18565 3b41d80e05649737c31591f349b649fa 145 Pfam PF12802 MarR family 36 93 2.7E-14 T 06-07-2017 LK06_RS15055 a7061faf395ef4c71e1ca6b8d713aa70 200 SUPERFAMILY SSF55729 1 175 8.03E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS15055 a7061faf395ef4c71e1ca6b8d713aa70 200 Pfam PF13302 Acetyltransferase (GNAT) domain 11 151 5.0E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS15055 a7061faf395ef4c71e1ca6b8d713aa70 200 Gene3D G3DSA:3.40.630.30 4 181 1.6E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS02680 9abe8ff104bc75b16718f7ee6984148f 477 Gene3D G3DSA:3.50.50.60 5 187 1.8E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02680 9abe8ff104bc75b16718f7ee6984148f 477 Gene3D G3DSA:3.50.50.60 289 332 1.8E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02680 9abe8ff104bc75b16718f7ee6984148f 477 Pfam PF04820 Tryptophan halogenase 101 408 3.6E-56 T 06-07-2017 IPR006905 Tryptophan halogenase LK06_RS02680 9abe8ff104bc75b16718f7ee6984148f 477 Pfam PF04820 Tryptophan halogenase 8 95 6.7E-23 T 06-07-2017 IPR006905 Tryptophan halogenase LK06_RS02680 9abe8ff104bc75b16718f7ee6984148f 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 3.1E-9 T 06-07-2017 LK06_RS02680 9abe8ff104bc75b16718f7ee6984148f 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 3.1E-9 T 06-07-2017 LK06_RS02680 9abe8ff104bc75b16718f7ee6984148f 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 3.1E-9 T 06-07-2017 LK06_RS02680 9abe8ff104bc75b16718f7ee6984148f 477 SUPERFAMILY SSF51905 6 182 8.37E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02680 9abe8ff104bc75b16718f7ee6984148f 477 SUPERFAMILY SSF51905 284 385 8.37E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS03295 777c78ab8e45a18b16d983eab7541cc8 200 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 107 4.2E-10 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS03295 777c78ab8e45a18b16d983eab7541cc8 200 SUPERFAMILY SSF50475 15 142 9.49E-10 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS03295 777c78ab8e45a18b16d983eab7541cc8 200 Gene3D G3DSA:2.30.110.10 8 141 9.9E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS24090 3dec58ad1dadfdccf7b43dee4bb2495a 137 Pfam PF03259 Roadblock/LC7 domain 9 99 2.2E-25 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS24090 3dec58ad1dadfdccf7b43dee4bb2495a 137 SMART SM00960 9 99 3.9E-33 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS24090 3dec58ad1dadfdccf7b43dee4bb2495a 137 SUPERFAMILY SSF103196 2 125 3.14E-32 T 06-07-2017 LK06_RS24090 3dec58ad1dadfdccf7b43dee4bb2495a 137 Gene3D G3DSA:3.30.450.30 3 123 2.5E-25 T 06-07-2017 LK06_RS13260 5dbe2a000d080fe654228bacf8019efe 222 SUPERFAMILY SSF51735 2 214 6.97E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13260 5dbe2a000d080fe654228bacf8019efe 222 Gene3D G3DSA:3.40.50.720 2 212 6.4E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS13260 5dbe2a000d080fe654228bacf8019efe 222 Pfam PF13460 NAD(P)H-binding 7 208 1.4E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS11115 9d9ea8dcd8fd94e9ceb84aac17613abb 155 Pfam PF00578 AhpC/TSA family 8 134 1.0E-36 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LK06_RS11115 9d9ea8dcd8fd94e9ceb84aac17613abb 155 Gene3D G3DSA:3.40.30.10 2 153 3.7E-49 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS11115 9d9ea8dcd8fd94e9ceb84aac17613abb 155 SUPERFAMILY SSF52833 4 153 1.16E-47 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS12625 9a4aa4116ec3a5c578893c23709eed63 130 PIRSF PIRSF028777 1 130 1.7E-53 T 06-07-2017 IPR031308 Uncharacterised conserved protein UCP028777 LK06_RS12625 9a4aa4116ec3a5c578893c23709eed63 130 Pfam PF03733 Inner membrane component domain 68 118 1.2E-17 T 06-07-2017 IPR005185 Inner membrane component domain LK06_RS12625 9a4aa4116ec3a5c578893c23709eed63 130 Pfam PF03733 Inner membrane component domain 4 53 1.4E-17 T 06-07-2017 IPR005185 Inner membrane component domain LK06_RS03840 d46ccc47fa1cc100f5899429b931a81a 448 Gene3D G3DSA:1.20.1250.20 34 220 3.8E-11 T 06-07-2017 LK06_RS03840 d46ccc47fa1cc100f5899429b931a81a 448 Gene3D G3DSA:1.20.1250.20 252 433 2.2E-18 T 06-07-2017 LK06_RS03840 d46ccc47fa1cc100f5899429b931a81a 448 Pfam PF11700 Vacuole effluxer Atg22 like 161 440 1.3E-62 T 06-07-2017 IPR024671 Autophagy-related protein 22-like LK06_RS03840 d46ccc47fa1cc100f5899429b931a81a 448 Pfam PF11700 Vacuole effluxer Atg22 like 18 157 7.5E-28 T 06-07-2017 IPR024671 Autophagy-related protein 22-like LK06_RS03840 d46ccc47fa1cc100f5899429b931a81a 448 SUPERFAMILY SSF103473 23 434 4.05E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS31725 9be604e72631a6737f0b7055f8dcdbd5 254 Pfam PF01061 ABC-2 type transporter 7 217 3.8E-29 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS31725 9be604e72631a6737f0b7055f8dcdbd5 254 PIRSF PIRSF006648 1 254 7.4E-44 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS26800 ce6f5c9f2fa37b998abeacaf4f623b28 338 Pfam PF07070 SpoOM protein 3 216 3.4E-74 T 06-07-2017 IPR009776 Sporulation stage 0, protein M LK06_RS14935 3764c3f7191aa2969b06359b15d0c5a6 390 Gene3D G3DSA:3.30.565.10 192 298 2.9E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14935 3764c3f7191aa2969b06359b15d0c5a6 390 SUPERFAMILY SSF55874 189 301 1.31E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS14935 3764c3f7191aa2969b06359b15d0c5a6 390 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 192 297 5.9E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS18895 f0e04ae240ae0c4c4159ad78c0c0594f 166 Pfam PF04075 Domain of unknown function (DUF385) 44 156 5.3E-23 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 LK06_RS18895 f0e04ae240ae0c4c4159ad78c0c0594f 166 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 49 159 6.8E-25 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 LK06_RS14455 6033b094ca86e74cb086bfa853f807a2 237 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 23 231 8.7E-48 T 06-07-2017 IPR015402 Protein of unknown function DUF1980 LK06_RS25680 9ab6b6d780b37fec3addaeed67bc77f6 525 SUPERFAMILY SSF103473 478 507 1.02E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS25680 9ab6b6d780b37fec3addaeed67bc77f6 525 SUPERFAMILY SSF103473 253 424 1.02E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS25680 9ab6b6d780b37fec3addaeed67bc77f6 525 SUPERFAMILY SSF103473 4 204 1.02E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS25680 9ab6b6d780b37fec3addaeed67bc77f6 525 Gene3D G3DSA:1.20.1250.20 480 506 8.1E-21 T 06-07-2017 LK06_RS25680 9ab6b6d780b37fec3addaeed67bc77f6 525 Gene3D G3DSA:1.20.1250.20 272 428 8.1E-21 T 06-07-2017 LK06_RS25680 9ab6b6d780b37fec3addaeed67bc77f6 525 Gene3D G3DSA:1.20.1250.20 12 196 1.7E-22 T 06-07-2017 LK06_RS25680 9ab6b6d780b37fec3addaeed67bc77f6 525 Pfam PF07690 Major Facilitator Superfamily 20 414 1.1E-40 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS29540 138a00b2607503c9c78f99f4951963da 120 SUPERFAMILY SSF56784 7 110 7.03E-20 T 06-07-2017 IPR023214 HAD-like domain LK06_RS29540 138a00b2607503c9c78f99f4951963da 120 Gene3D G3DSA:3.40.50.1000 6 109 1.1E-21 T 06-07-2017 IPR023214 HAD-like domain LK06_RS29540 138a00b2607503c9c78f99f4951963da 120 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 102 1.4E-5 T 06-07-2017 IPR023214 HAD-like domain LK06_RS29540 138a00b2607503c9c78f99f4951963da 120 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 51 103 4.2E-13 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 LK06_RS25585 4a6079f24e5aa23669fd1414fdbf0a72 68 Pfam PF12728 Helix-turn-helix domain 5 59 4.7E-10 T 06-07-2017 LK06_RS25585 4a6079f24e5aa23669fd1414fdbf0a72 68 SUPERFAMILY SSF46955 5 59 4.03E-5 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 326 2.3E-89 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 SUPERFAMILY SSF52374 9 322 9.92E-105 T 06-07-2017 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 Gene3D G3DSA:3.40.50.620 9 73 2.0E-43 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 Gene3D G3DSA:3.40.50.620 199 253 2.0E-43 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 Gene3D G3DSA:1.10.1160.10 256 338 1.7E-29 T 06-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 197 207 2.5E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 12 24 2.5E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 41 54 2.5E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 26 37 2.5E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 213 221 2.5E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 Gene3D G3DSA:1.10.10.350 395 489 1.6E-21 T 06-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 Gene3D G3DSA:3.90.800.10 74 197 4.3E-40 T 06-07-2017 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 9 489 32.274 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 9 487 5.5E-143 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 LK06_RS24130 214928e34de7a5b2c3ec6840c76b5887 494 SUPERFAMILY SSF48163 323 489 1.7E-35 T 06-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 LK06_RS20790 fd930e1b2b33726cf90010630b02227e 295 SUPERFAMILY SSF53720 7 256 3.93E-46 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS20790 fd930e1b2b33726cf90010630b02227e 295 Pfam PF00171 Aldehyde dehydrogenase family 24 255 2.4E-41 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS20790 fd930e1b2b33726cf90010630b02227e 295 Gene3D G3DSA:3.40.605.10 6 255 7.4E-56 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS11630 b66a845b5b1a062b942154ed1b87bb26 748 SUPERFAMILY SSF53448 2 232 1.13E-52 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11630 b66a845b5b1a062b942154ed1b87bb26 748 SUPERFAMILY SSF53756 502 698 3.66E-7 T 06-07-2017 LK06_RS11630 b66a845b5b1a062b942154ed1b87bb26 748 Gene3D G3DSA:3.90.550.10 2 201 7.2E-51 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11630 b66a845b5b1a062b942154ed1b87bb26 748 Pfam PF00535 Glycosyl transferase family 2 5 141 1.4E-34 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS11630 b66a845b5b1a062b942154ed1b87bb26 748 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 343 699 2.1E-100 T 06-07-2017 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 LK06_RS07895 8f113c575e1c1dc28f3012360a1d705d 159 Gene3D G3DSA:3.30.530.20 4 146 6.9E-21 T 06-07-2017 IPR023393 START-like domain LK06_RS07895 8f113c575e1c1dc28f3012360a1d705d 159 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 123 6.1E-15 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain LK06_RS07895 8f113c575e1c1dc28f3012360a1d705d 159 SUPERFAMILY SSF55961 1 148 4.47E-40 T 06-07-2017 LK06_RS12060 53fd1029cc1ab9d2da2a4702f437a0b8 125 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 117 2.6E-22 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 LK06_RS12060 53fd1029cc1ab9d2da2a4702f437a0b8 125 Pfam PF13466 STAS domain 31 105 4.0E-17 T 06-07-2017 IPR002645 STAS domain LK06_RS12060 53fd1029cc1ab9d2da2a4702f437a0b8 125 SUPERFAMILY SSF52091 16 121 1.45E-25 T 06-07-2017 IPR002645 STAS domain LK06_RS12060 53fd1029cc1ab9d2da2a4702f437a0b8 125 Gene3D G3DSA:3.30.750.24 16 121 9.6E-35 T 06-07-2017 IPR002645 STAS domain LK06_RS01075 dc154b21d076de9f8484071bd290ccbb 124 SUPERFAMILY SSF51395 27 108 1.71E-18 T 06-07-2017 LK06_RS01075 dc154b21d076de9f8484071bd290ccbb 124 Pfam PF01070 FMN-dependent dehydrogenase 27 109 6.4E-27 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 LK06_RS01075 dc154b21d076de9f8484071bd290ccbb 124 Gene3D G3DSA:3.20.20.70 28 108 4.3E-28 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS26270 260ac1f45e171f6867898fa773035f4c 57 SUPERFAMILY SSF47598 5 47 2.14E-6 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 LK06_RS26270 260ac1f45e171f6867898fa773035f4c 57 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 45 8.7E-6 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 LK06_RS26270 260ac1f45e171f6867898fa773035f4c 57 Gene3D G3DSA:1.10.1220.10 4 47 3.1E-4 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 LK06_RS29915 aea16c43fbece73657dd6f3fc57af416 227 Gene3D G3DSA:3.20.20.190 3 219 2.9E-59 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS29915 aea16c43fbece73657dd6f3fc57af416 227 SUPERFAMILY SSF51695 4 220 1.54E-58 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS29915 aea16c43fbece73657dd6f3fc57af416 227 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 218 2.0E-30 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 LK06_RS17220 da234edbb19b4e8e68920adc4706deb6 184 Gene3D G3DSA:3.40.630.30 13 173 3.1E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS17220 da234edbb19b4e8e68920adc4706deb6 184 SUPERFAMILY SSF55729 9 168 9.17E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS31155 1d29e814d9bbf8d7b1040a11e1a7e7fe 276 SUPERFAMILY SSF81606 89 270 2.75E-8 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS31155 1d29e814d9bbf8d7b1040a11e1a7e7fe 276 SMART SM00331 56 269 5.3E-30 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS31155 1d29e814d9bbf8d7b1040a11e1a7e7fe 276 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 82 268 2.9E-43 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS26075 aeb763db2493eadd24609011235f8bef 151 SUPERFAMILY SSF55874 42 142 1.34E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS26075 aeb763db2493eadd24609011235f8bef 151 Gene3D G3DSA:3.30.565.10 44 142 8.3E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS26075 aeb763db2493eadd24609011235f8bef 151 Pfam PF13581 Histidine kinase-like ATPase domain 23 139 1.8E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17215 e82fadebe22bf52ce4c27a2ffc540a4d 186 Gene3D G3DSA:1.25.40.10 74 140 7.8E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS08940 07624962b9f61a27f83e247090ff36c0 480 SUPERFAMILY SSF51905 15 200 1.83E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS08940 07624962b9f61a27f83e247090ff36c0 480 SUPERFAMILY SSF51905 321 414 1.83E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS08940 07624962b9f61a27f83e247090ff36c0 480 Gene3D G3DSA:3.50.50.60 19 207 1.3E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS08940 07624962b9f61a27f83e247090ff36c0 480 Gene3D G3DSA:3.50.50.60 315 386 1.3E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS08940 07624962b9f61a27f83e247090ff36c0 480 Pfam PF12831 FAD dependent oxidoreductase 20 192 2.0E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 PRINTS PR01703 Manganese superoxide dismutase signature 165 177 3.4E-19 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 3.4E-19 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 3.4E-19 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 3.4E-19 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 PRINTS PR01703 Manganese superoxide dismutase signature 127 135 3.4E-19 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 101 200 2.1E-31 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 SUPERFAMILY SSF46609 3 84 1.7E-29 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 83 8.9E-30 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 167 174 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 SUPERFAMILY SSF54719 100 205 3.8E-37 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 PIRSF PIRSF000349 1 209 6.1E-69 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LK06_RS09995 cb6b6dec88f10a39b74942eb7ae8ee91 215 Gene3D G3DSA:1.10.287.990 22 84 8.3E-22 T 06-07-2017 LK06_RS02760 1659e23cc4298691cfbb31abc1122640 342 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 10 334 58.185 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS02760 1659e23cc4298691cfbb31abc1122640 342 SUPERFAMILY SSF53901 13 334 1.08E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS02760 1659e23cc4298691cfbb31abc1122640 342 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 12 334 2.1E-94 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS02760 1659e23cc4298691cfbb31abc1122640 342 Gene3D G3DSA:3.40.47.10 11 166 2.2E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS02760 1659e23cc4298691cfbb31abc1122640 342 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 193 2.1E-25 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS02760 1659e23cc4298691cfbb31abc1122640 342 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 247 334 1.2E-28 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS02760 1659e23cc4298691cfbb31abc1122640 342 Gene3D G3DSA:3.40.47.10 167 336 4.3E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS27985 e4f2a5c7452daa232fb4eec807ec0919 675 Pfam PF01642 Methylmalonyl-CoA mutase 3 495 9.2E-130 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS27985 e4f2a5c7452daa232fb4eec807ec0919 675 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 7 501 1.7E-139 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS27985 e4f2a5c7452daa232fb4eec807ec0919 675 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 536 665 1.4E-38 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS27985 e4f2a5c7452daa232fb4eec807ec0919 675 SUPERFAMILY SSF52242 514 658 7.2E-44 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS27985 e4f2a5c7452daa232fb4eec807ec0919 675 Pfam PF02310 B12 binding domain 538 644 4.2E-17 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS27985 e4f2a5c7452daa232fb4eec807ec0919 675 Gene3D G3DSA:3.20.20.240 3 497 1.3E-187 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS27985 e4f2a5c7452daa232fb4eec807ec0919 675 SUPERFAMILY SSF51703 4 497 9.42E-163 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS27985 e4f2a5c7452daa232fb4eec807ec0919 675 Gene3D G3DSA:3.40.50.280 513 656 4.8E-48 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 SUPERFAMILY SSF52518 5 282 3.99E-81 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 ProSitePatterns PS00802 Transketolase signature 2. 411 427 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 Gene3D G3DSA:3.40.50.970 299 479 2.5E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 Gene3D G3DSA:3.40.50.970 5 278 1.2E-85 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 SMART SM00861 305 468 3.6E-46 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 SUPERFAMILY SSF52518 296 470 4.85E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 Pfam PF02779 Transketolase, pyrimidine binding domain 304 465 4.1E-37 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 SUPERFAMILY SSF52922 478 606 1.96E-28 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 Gene3D G3DSA:3.40.50.920 481 607 5.3E-33 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 12 263 1.5E-51 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS28080 e187c3e9d743bd299689f0add1f66fd4 615 Pfam PF02780 Transketolase, C-terminal domain 485 601 2.9E-30 T 06-07-2017 IPR033248 Transketolase, C-terminal domain LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 5 333 42.416 T 06-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 SUPERFAMILY SSF52374 7 332 1.58E-98 T 06-07-2017 LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 5 332 2.5E-107 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 24 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 Gene3D G3DSA:1.10.240.10 215 308 1.0E-13 T 06-07-2017 LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 Gene3D G3DSA:3.40.50.620 4 214 7.1E-90 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 Pfam PF00579 tRNA synthetases class I (W and Y) 3 287 1.6E-79 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 1.5E-26 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 19 35 1.5E-26 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 199 209 1.5E-26 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LK06_RS20490 398a72d7e7af969fe7372b52422abdd8 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 146 167 1.5E-26 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LK06_RS22030 cebcbab454e5598c45ba4b8d401bf100 362 Pfam PF13490 Putative zinc-finger 21 49 1.8E-9 T 06-07-2017 IPR027383 Putative zinc-finger LK06_RS27095 2a1ef08044f77b2c59d4795ef5b519c2 145 Pfam PF13581 Histidine kinase-like ATPase domain 29 137 1.5E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS27095 2a1ef08044f77b2c59d4795ef5b519c2 145 SUPERFAMILY SSF55874 53 140 1.51E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS18950 3d2fe99a481f7cc69962d8acf348fc2d 384 Gene3D G3DSA:3.40.47.10 148 184 6.4E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18950 3d2fe99a481f7cc69962d8acf348fc2d 384 Gene3D G3DSA:3.40.47.10 248 334 6.4E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18950 3d2fe99a481f7cc69962d8acf348fc2d 384 Gene3D G3DSA:3.40.47.10 13 116 4.8E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18950 3d2fe99a481f7cc69962d8acf348fc2d 384 Gene3D G3DSA:3.40.47.10 200 227 4.8E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18950 3d2fe99a481f7cc69962d8acf348fc2d 384 SUPERFAMILY SSF53901 11 230 9.28E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18950 3d2fe99a481f7cc69962d8acf348fc2d 384 SUPERFAMILY SSF53901 253 369 9.86E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS18950 3d2fe99a481f7cc69962d8acf348fc2d 384 PIRSF PIRSF000429 6 375 5.9E-18 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS30700 f6ddf706251290e00e9068da713dcd88 145 Pfam PF03779 SPW repeat 36 83 6.3E-17 T 06-07-2017 IPR005530 SPW repeat LK06_RS30700 f6ddf706251290e00e9068da713dcd88 145 Pfam PF03779 SPW repeat 91 137 1.2E-16 T 06-07-2017 IPR005530 SPW repeat LK06_RS03040 55e0a3237f8e74f3a1e9d552c140bc8f 106 Pfam PF00550 Phosphopantetheine attachment site 24 77 1.2E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03040 55e0a3237f8e74f3a1e9d552c140bc8f 106 Gene3D G3DSA:1.10.1200.10 19 95 3.8E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS03040 55e0a3237f8e74f3a1e9d552c140bc8f 106 SUPERFAMILY SSF47336 19 97 5.76E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS15360 2ae903f0c490020ffbd92aa67efa63ba 224 Pfam PF07729 FCD domain 90 212 7.0E-24 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS15360 2ae903f0c490020ffbd92aa67efa63ba 224 SMART SM00345 22 80 2.1E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS15360 2ae903f0c490020ffbd92aa67efa63ba 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.0E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS15360 2ae903f0c490020ffbd92aa67efa63ba 224 Gene3D G3DSA:1.20.120.530 84 213 1.1E-29 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS15360 2ae903f0c490020ffbd92aa67efa63ba 224 SUPERFAMILY SSF46785 14 84 1.14E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15360 2ae903f0c490020ffbd92aa67efa63ba 224 SMART SM00895 90 214 4.7E-18 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS15360 2ae903f0c490020ffbd92aa67efa63ba 224 Gene3D G3DSA:1.10.10.10 7 80 3.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15360 2ae903f0c490020ffbd92aa67efa63ba 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 2.2E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS15360 2ae903f0c490020ffbd92aa67efa63ba 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 2.2E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS15360 2ae903f0c490020ffbd92aa67efa63ba 224 SUPERFAMILY SSF48008 86 215 1.54E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS15395 1b1e01ef794213c45a8356b15659189e 332 Pfam PF01636 Phosphotransferase enzyme family 18 267 3.3E-30 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS15395 1b1e01ef794213c45a8356b15659189e 332 Gene3D G3DSA:3.30.200.20 2 95 1.2E-15 T 06-07-2017 LK06_RS15395 1b1e01ef794213c45a8356b15659189e 332 Gene3D G3DSA:3.90.1200.10 99 328 3.0E-22 T 06-07-2017 LK06_RS15395 1b1e01ef794213c45a8356b15659189e 332 SUPERFAMILY SSF56112 2 305 4.23E-44 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS01470 4ec8f3ac65d8fe60fb02daf8ed790e5a 214 Gene3D G3DSA:3.90.45.10 24 188 2.2E-49 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS01470 4ec8f3ac65d8fe60fb02daf8ed790e5a 214 PRINTS PR01576 Peptide deformylase signature 124 135 8.0E-32 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS01470 4ec8f3ac65d8fe60fb02daf8ed790e5a 214 PRINTS PR01576 Peptide deformylase signature 55 84 8.0E-32 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS01470 4ec8f3ac65d8fe60fb02daf8ed790e5a 214 PRINTS PR01576 Peptide deformylase signature 136 154 8.0E-32 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS01470 4ec8f3ac65d8fe60fb02daf8ed790e5a 214 PRINTS PR01576 Peptide deformylase signature 155 184 8.0E-32 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS01470 4ec8f3ac65d8fe60fb02daf8ed790e5a 214 Pfam PF01327 Polypeptide deformylase 25 185 2.0E-38 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS01470 4ec8f3ac65d8fe60fb02daf8ed790e5a 214 SUPERFAMILY SSF56420 23 186 2.62E-46 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS01470 4ec8f3ac65d8fe60fb02daf8ed790e5a 214 PIRSF PIRSF004749 7 206 6.3E-51 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS01470 4ec8f3ac65d8fe60fb02daf8ed790e5a 214 Hamap MF_00163 Peptide deformylase [def]. 22 196 24.369 T 06-07-2017 IPR023635 Peptide deformylase LK06_RS28535 501e67fda0c26fa64ccf56ae564c2d99 336 Pfam PF11258 Protein of unknown function (DUF3048) 65 329 8.3E-62 T 06-07-2017 IPR021416 Protein of unknown function DUF3048 LK06_RS28535 501e67fda0c26fa64ccf56ae564c2d99 336 SUPERFAMILY SSF159774 64 334 7.45E-78 T 06-07-2017 IPR023158 YerB-like domain LK06_RS28535 501e67fda0c26fa64ccf56ae564c2d99 336 Gene3D G3DSA:3.50.90.10 49 334 2.1E-73 T 06-07-2017 IPR023158 YerB-like domain LK06_RS16230 d77ac3dbdb9210625ec9ead85b2095ed 265 Pfam PF08282 haloacid dehalogenase-like hydrolase 8 260 7.6E-44 T 06-07-2017 IPR023214 HAD-like domain LK06_RS16230 d77ac3dbdb9210625ec9ead85b2095ed 265 SUPERFAMILY SSF56784 5 264 1.96E-56 T 06-07-2017 IPR023214 HAD-like domain LK06_RS16230 d77ac3dbdb9210625ec9ead85b2095ed 265 Gene3D G3DSA:3.40.50.1000 5 75 3.2E-49 T 06-07-2017 IPR023214 HAD-like domain LK06_RS16230 d77ac3dbdb9210625ec9ead85b2095ed 265 Gene3D G3DSA:3.40.50.1000 169 264 3.2E-49 T 06-07-2017 IPR023214 HAD-like domain LK06_RS16230 d77ac3dbdb9210625ec9ead85b2095ed 265 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 7 260 1.3E-43 T 06-07-2017 IPR000150 Cof protein GO:0016787 LK06_RS05260 22e1d0023cf16ec3e69b441ae5ca19d3 280 SUPERFAMILY SSF103481 25 100 5.1E-6 T 06-07-2017 LK06_RS15690 dced572ad126b1a667f4e5e9a2cbf0a7 540 Pfam PF00069 Protein kinase domain 9 248 1.3E-36 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS15690 dced572ad126b1a667f4e5e9a2cbf0a7 540 SUPERFAMILY SSF56112 402 463 1.15E-60 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS15690 dced572ad126b1a667f4e5e9a2cbf0a7 540 SUPERFAMILY SSF56112 5 259 1.15E-60 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS15690 dced572ad126b1a667f4e5e9a2cbf0a7 540 SMART SM00220 9 258 7.3E-40 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS15690 dced572ad126b1a667f4e5e9a2cbf0a7 540 Gene3D G3DSA:1.10.510.10 101 259 3.4E-37 T 06-07-2017 LK06_RS15690 dced572ad126b1a667f4e5e9a2cbf0a7 540 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 123 135 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS15690 dced572ad126b1a667f4e5e9a2cbf0a7 540 Gene3D G3DSA:3.30.200.20 3 100 6.6E-17 T 06-07-2017 LK06_RS15110 f05be90979a8f539c8572e77ced5b71c 235 SUPERFAMILY SSF141523 81 202 1.96E-20 T 06-07-2017 LK06_RS15110 f05be90979a8f539c8572e77ced5b71c 235 Pfam PF03734 L,D-transpeptidase catalytic domain 84 202 9.7E-13 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 LK06_RS15110 f05be90979a8f539c8572e77ced5b71c 235 Gene3D G3DSA:2.40.440.10 83 202 7.0E-14 T 06-07-2017 LK06_RS26295 4df237d3abac1315c640660e80de5ff8 255 SUPERFAMILY SSF53335 23 210 1.14E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26295 4df237d3abac1315c640660e80de5ff8 255 Pfam PF01596 O-methyltransferase 53 195 1.9E-15 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 LK06_RS26295 4df237d3abac1315c640660e80de5ff8 255 Gene3D G3DSA:3.40.50.150 22 209 1.3E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS11600 59175c8e5e0a85798f8e33d329492204 410 Gene3D G3DSA:3.30.200.20 4 72 2.5E-16 T 06-07-2017 LK06_RS11600 59175c8e5e0a85798f8e33d329492204 410 SMART SM00220 9 273 7.0E-60 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS11600 59175c8e5e0a85798f8e33d329492204 410 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 LK06_RS11600 59175c8e5e0a85798f8e33d329492204 410 SUPERFAMILY SSF56112 6 267 5.93E-66 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS11600 59175c8e5e0a85798f8e33d329492204 410 Pfam PF00069 Protein kinase domain 9 262 6.4E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 LK06_RS11600 59175c8e5e0a85798f8e33d329492204 410 Gene3D G3DSA:1.10.510.10 73 263 5.8E-47 T 06-07-2017 LK06_RS22255 d74a8bcea915282c9183108a5dbe6b38 404 Gene3D G3DSA:3.40.50.720 130 357 6.3E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS22255 d74a8bcea915282c9183108a5dbe6b38 404 Pfam PF00899 ThiF family 127 357 5.3E-18 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 LK06_RS22255 d74a8bcea915282c9183108a5dbe6b38 404 SUPERFAMILY SSF69572 131 356 4.19E-11 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 LK06_RS22255 d74a8bcea915282c9183108a5dbe6b38 404 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 245 378 4.4E-10 T 06-07-2017 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain LK06_RS10085 86a4187bc92e1b7d9f5463b8d665be3c 252 SMART SM00382 22 205 1.3E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS10085 86a4187bc92e1b7d9f5463b8d665be3c 252 SUPERFAMILY SSF52540 2 216 5.43E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10085 86a4187bc92e1b7d9f5463b8d665be3c 252 Gene3D G3DSA:3.40.50.300 2 217 2.2E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10085 86a4187bc92e1b7d9f5463b8d665be3c 252 Pfam PF00005 ABC transporter 25 159 1.2E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS01825 2938a0f1a14ebe4042cf511b3a565922 971 Pfam PF08665 PglZ domain 529 700 9.2E-9 T 06-07-2017 IPR013973 PglZ domain LK06_RS01825 2938a0f1a14ebe4042cf511b3a565922 971 SUPERFAMILY SSF53649 528 779 5.49E-7 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 LK06_RS07435 744cb22ab72e4b59a439694a185eba51 66 Pfam PF02597 ThiS family 5 66 4.0E-15 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 LK06_RS07435 744cb22ab72e4b59a439694a185eba51 66 Gene3D G3DSA:3.10.20.30 1 66 1.1E-25 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS07435 744cb22ab72e4b59a439694a185eba51 66 SUPERFAMILY SSF54285 1 66 3.34E-16 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp LK06_RS07435 744cb22ab72e4b59a439694a185eba51 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 5.2E-22 T 06-07-2017 IPR010035 ThiS, thiamine-biosynthesis LK06_RS07150 28434defdae7fd57dc549af65e381b71 369 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 227 236 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 LK06_RS07150 28434defdae7fd57dc549af65e381b71 369 Gene3D G3DSA:3.90.1150.10 271 365 1.2E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS07150 28434defdae7fd57dc549af65e381b71 369 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 362 1.9E-96 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LK06_RS07150 28434defdae7fd57dc549af65e381b71 369 Pfam PF00155 Aminotransferase class I and II 29 360 4.3E-67 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS07150 28434defdae7fd57dc549af65e381b71 369 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 364 53.896 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LK06_RS07150 28434defdae7fd57dc549af65e381b71 369 SUPERFAMILY SSF53383 28 363 4.49E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS07150 28434defdae7fd57dc549af65e381b71 369 Gene3D G3DSA:3.40.640.10 46 270 1.8E-64 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS11905 61b73d0f6e31e325dd53eb940119dfa4 161 Pfam PF05995 Cysteine dioxygenase type I 19 150 9.9E-23 T 06-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 LK06_RS11905 61b73d0f6e31e325dd53eb940119dfa4 161 Gene3D G3DSA:2.60.120.10 46 152 2.5E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS11905 61b73d0f6e31e325dd53eb940119dfa4 161 SUPERFAMILY SSF51182 19 149 9.57E-32 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS11685 ead56f7a41dde0f4a794775187026cc1 282 Gene3D G3DSA:3.40.50.300 42 252 3.1E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11685 ead56f7a41dde0f4a794775187026cc1 282 SMART SM00382 56 239 1.5E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS11685 ead56f7a41dde0f4a794775187026cc1 282 SUPERFAMILY SSF52540 42 245 1.33E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11685 ead56f7a41dde0f4a794775187026cc1 282 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS11685 ead56f7a41dde0f4a794775187026cc1 282 Pfam PF00005 ABC transporter 48 181 1.3E-16 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 Pfam PF07690 Major Facilitator Superfamily 17 406 8.9E-60 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 SUPERFAMILY SSF103473 4 199 5.89E-75 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 SUPERFAMILY SSF103473 245 466 5.89E-75 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 1.2E-10 T 06-07-2017 LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 75 97 1.2E-10 T 06-07-2017 LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 335 355 1.2E-10 T 06-07-2017 LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 1.2E-10 T 06-07-2017 LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 1.2E-10 T 06-07-2017 LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 414 2.5E-79 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 Gene3D G3DSA:1.20.1250.20 7 198 3.9E-36 T 06-07-2017 LK06_RS09275 70fccfd56d999c61e0195680a5c00860 483 Gene3D G3DSA:1.20.1250.20 269 459 1.2E-20 T 06-07-2017 LK06_RS17910 b0f15b758ff502d728405f6774163e5b 377 Pfam PF03459 TOBE domain 307 366 2.6E-7 T 06-07-2017 IPR005116 Transport-associated OB, type 1 LK06_RS17910 b0f15b758ff502d728405f6774163e5b 377 Gene3D G3DSA:2.40.50.100 361 375 5.0E-7 T 06-07-2017 LK06_RS17910 b0f15b758ff502d728405f6774163e5b 377 Gene3D G3DSA:2.40.50.100 241 284 5.0E-7 T 06-07-2017 LK06_RS17910 b0f15b758ff502d728405f6774163e5b 377 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS17910 b0f15b758ff502d728405f6774163e5b 377 SMART SM00382 30 213 1.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS17910 b0f15b758ff502d728405f6774163e5b 377 Gene3D G3DSA:2.40.50.140 285 359 1.4E-8 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS17910 b0f15b758ff502d728405f6774163e5b 377 SUPERFAMILY SSF50331 238 375 1.84E-20 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal LK06_RS17910 b0f15b758ff502d728405f6774163e5b 377 SUPERFAMILY SSF52540 6 245 9.84E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS17910 b0f15b758ff502d728405f6774163e5b 377 Pfam PF00005 ABC transporter 22 163 7.3E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS17910 b0f15b758ff502d728405f6774163e5b 377 Gene3D G3DSA:3.40.50.300 4 236 2.1E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26100 6292f843aadcb6e159f4a2f230d7aba6 378 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 116 128 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS26100 6292f843aadcb6e159f4a2f230d7aba6 378 Gene3D G3DSA:1.10.540.10 3 110 3.9E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS26100 6292f843aadcb6e159f4a2f230d7aba6 378 Gene3D G3DSA:1.20.140.10 210 373 1.6E-53 T 06-07-2017 LK06_RS26100 6292f843aadcb6e159f4a2f230d7aba6 378 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 114 192 1.7E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS26100 6292f843aadcb6e159f4a2f230d7aba6 378 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 109 3.5E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS26100 6292f843aadcb6e159f4a2f230d7aba6 378 Gene3D G3DSA:2.40.110.10 113 209 3.1E-30 T 06-07-2017 LK06_RS26100 6292f843aadcb6e159f4a2f230d7aba6 378 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 219 368 2.4E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS26100 6292f843aadcb6e159f4a2f230d7aba6 378 SUPERFAMILY SSF47203 217 371 5.64E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS26100 6292f843aadcb6e159f4a2f230d7aba6 378 SUPERFAMILY SSF56645 4 230 1.57E-49 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS25265 497537eccf4fba02eddeedfd5006d4f5 252 Gene3D G3DSA:3.90.79.10 3 163 1.3E-49 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS25265 497537eccf4fba02eddeedfd5006d4f5 252 SUPERFAMILY SSF55811 5 172 7.99E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS25265 497537eccf4fba02eddeedfd5006d4f5 252 PRINTS PR00502 NUDIX hydrolase family signature 43 57 1.0E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS25265 497537eccf4fba02eddeedfd5006d4f5 252 PRINTS PR00502 NUDIX hydrolase family signature 57 72 1.0E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS25265 497537eccf4fba02eddeedfd5006d4f5 252 Gene3D G3DSA:1.10.10.10 167 239 8.0E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25265 497537eccf4fba02eddeedfd5006d4f5 252 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS25265 497537eccf4fba02eddeedfd5006d4f5 252 Pfam PF00293 NUDIX domain 14 137 7.1E-21 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS25265 497537eccf4fba02eddeedfd5006d4f5 252 SUPERFAMILY SSF46785 175 243 3.81E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26490 609475d18c3ee47a9423ddb24d8842e7 88 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 32 67 1.2E-9 T 06-07-2017 IPR006530 YD repeat LK06_RS26490 609475d18c3ee47a9423ddb24d8842e7 88 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 12 46 1.4E-5 T 06-07-2017 IPR006530 YD repeat LK06_RS26490 609475d18c3ee47a9423ddb24d8842e7 88 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 52 84 1.5E-5 T 06-07-2017 IPR006530 YD repeat LK06_RS26490 609475d18c3ee47a9423ddb24d8842e7 88 Pfam PF05593 RHS Repeat 52 86 2.3E-8 T 06-07-2017 IPR031325 RHS repeat LK06_RS26490 609475d18c3ee47a9423ddb24d8842e7 88 Pfam PF05593 RHS Repeat 12 47 4.3E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS24620 3f2560fb782f14c368000c4a791f94c0 511 Gene3D G3DSA:3.40.309.10 280 458 1.1E-63 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS24620 3f2560fb782f14c368000c4a791f94c0 511 SUPERFAMILY SSF53720 21 494 1.31E-160 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS24620 3f2560fb782f14c368000c4a791f94c0 511 Gene3D G3DSA:3.40.605.10 24 279 2.7E-96 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS24620 3f2560fb782f14c368000c4a791f94c0 511 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 LK06_RS24620 3f2560fb782f14c368000c4a791f94c0 511 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 LK06_RS24620 3f2560fb782f14c368000c4a791f94c0 511 Pfam PF00171 Aldehyde dehydrogenase family 33 491 4.5E-172 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS19600 f3d6bdc0e26a0399acdb918c966d5fdb 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 2.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS19600 f3d6bdc0e26a0399acdb918c966d5fdb 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 240 254 2.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS19600 f3d6bdc0e26a0399acdb918c966d5fdb 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS19600 f3d6bdc0e26a0399acdb918c966d5fdb 321 Gene3D G3DSA:3.40.50.1820 24 295 3.7E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS19600 f3d6bdc0e26a0399acdb918c966d5fdb 321 SUPERFAMILY SSF53474 16 293 9.68E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS19600 f3d6bdc0e26a0399acdb918c966d5fdb 321 Pfam PF12146 Serine aminopeptidase, S33 41 282 1.4E-20 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 LK06_RS27710 da94b50d5896800c7abf3526c0712c7e 71 Pfam PF01361 Tautomerase enzyme 2 61 3.0E-18 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 LK06_RS27710 da94b50d5896800c7abf3526c0712c7e 71 Gene3D G3DSA:3.30.429.20 1 60 2.4E-13 T 06-07-2017 LK06_RS27710 da94b50d5896800c7abf3526c0712c7e 71 SUPERFAMILY SSF55331 2 62 3.66E-12 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily LK06_RS20300 8b54abab7306f7eba4dfca1936a010a1 140 SUPERFAMILY SSF52242 6 133 5.23E-49 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS20300 8b54abab7306f7eba4dfca1936a010a1 140 Gene3D G3DSA:3.40.50.280 7 133 7.0E-55 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS20300 8b54abab7306f7eba4dfca1936a010a1 140 Pfam PF02310 B12 binding domain 8 100 1.1E-22 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS20300 8b54abab7306f7eba4dfca1936a010a1 140 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 8 134 7.1E-50 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS28085 7988ea45c601361e0504b11ff231b799 264 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 5 254 9.3E-59 T 06-07-2017 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 LK06_RS14920 f10a686aea111e48829450a8ecd81ecb 186 Pfam PF03029 Conserved hypothetical ATP binding protein 15 182 3.0E-20 T 06-07-2017 IPR004130 GPN-loop GTPase LK06_RS14920 f10a686aea111e48829450a8ecd81ecb 186 SUPERFAMILY SSF52540 10 183 1.42E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14920 f10a686aea111e48829450a8ecd81ecb 186 Gene3D G3DSA:3.40.50.300 10 111 1.9E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24810 115433c0ae4ae939b4fcc4ac87d2afc6 509 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 3 454 1.8E-55 T 06-07-2017 IPR007795 Type VII secretion system EccB LK06_RS24810 115433c0ae4ae939b4fcc4ac87d2afc6 509 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 505 1.5E-81 T 06-07-2017 IPR007795 Type VII secretion system EccB LK06_RS19850 4e0d9043cfff89843216b9b4fd93e602 438 Pfam PF07730 Histidine kinase 207 272 1.5E-17 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS19850 4e0d9043cfff89843216b9b4fd93e602 438 SUPERFAMILY SSF55874 339 436 4.26E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13915 e98723d4fbee0132d22b94a7387e11a5 297 Pfam PF13641 Glycosyltransferase like family 2 10 211 3.1E-11 T 06-07-2017 LK06_RS13915 e98723d4fbee0132d22b94a7387e11a5 297 SUPERFAMILY SSF53448 6 225 9.38E-36 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS13915 e98723d4fbee0132d22b94a7387e11a5 297 Gene3D G3DSA:3.90.550.10 10 227 1.2E-19 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS25105 03e54d499c1355c035c92dda7aa44af0 150 Pfam PF12802 MarR family 30 90 6.3E-11 T 06-07-2017 LK06_RS25105 03e54d499c1355c035c92dda7aa44af0 150 SUPERFAMILY SSF46785 5 139 1.79E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25105 03e54d499c1355c035c92dda7aa44af0 150 SMART SM00347 25 129 1.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS25105 03e54d499c1355c035c92dda7aa44af0 150 Gene3D G3DSA:1.10.10.10 4 139 3.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28320 81225d64bec4b13605295fc79f1970ea 470 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 119 398 4.7E-28 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD LK06_RS30065 5368a842bd9402ddb9195944f805efad 267 SUPERFAMILY SSF55874 26 137 1.61E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS30065 5368a842bd9402ddb9195944f805efad 267 Pfam PF13581 Histidine kinase-like ATPase domain 14 134 4.1E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS30065 5368a842bd9402ddb9195944f805efad 267 Gene3D G3DSA:3.30.565.10 42 138 6.6E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01945 dc6202af929e6f1e6ea1f89abe489966 547 Gene3D G3DSA:3.40.50.720 19 242 7.0E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01945 dc6202af929e6f1e6ea1f89abe489966 547 Pfam PF13460 NAD(P)H-binding 26 168 1.1E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01945 dc6202af929e6f1e6ea1f89abe489966 547 SUPERFAMILY SSF51735 21 300 1.74E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01945 dc6202af929e6f1e6ea1f89abe489966 547 SUPERFAMILY SSF55961 359 505 1.05E-5 T 06-07-2017 LK06_RS01945 dc6202af929e6f1e6ea1f89abe489966 547 Pfam PF11066 Protein of unknown function (DUF2867) 351 496 2.1E-42 T 06-07-2017 IPR021295 Protein of unknown function DUF2867 LK06_RS23445 a6edbb465820582ef9b84b3f550420f0 158 SUPERFAMILY SSF46785 7 152 3.98E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23445 a6edbb465820582ef9b84b3f550420f0 158 Pfam PF12802 MarR family 40 100 1.5E-10 T 06-07-2017 LK06_RS23445 a6edbb465820582ef9b84b3f550420f0 158 Gene3D G3DSA:1.10.10.10 3 153 5.2E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23445 a6edbb465820582ef9b84b3f550420f0 158 SMART SM00347 34 137 3.5E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 SUPERFAMILY SSF48264 21 406 5.63E-78 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 PRINTS PR00359 B-class P450 signature 278 289 1.8E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 PRINTS PR00359 B-class P450 signature 98 109 1.8E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 PRINTS PR00359 B-class P450 signature 145 161 1.8E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 PRINTS PR00359 B-class P450 signature 346 355 1.8E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 PRINTS PR00359 B-class P450 signature 355 366 1.8E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 PRINTS PR00359 B-class P450 signature 297 324 1.8E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 PRINTS PR00359 B-class P450 signature 199 221 1.8E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 PRINTS PR00359 B-class P450 signature 162 177 1.8E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 PRINTS PR00359 B-class P450 signature 325 340 1.8E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 Gene3D G3DSA:1.10.630.10 26 406 1.8E-99 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS02075 5c062f5d51dfa70ee15a893628ac4b21 406 Pfam PF00067 Cytochrome P450 279 375 7.5E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22645 c46ae27d33ec301764cf345edb2c4ab6 426 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 11 412 2.1E-87 T 06-07-2017 IPR026337 HEXXH motif domain LK06_RS26660 ff16a10bcf7aecef7efb35a295d08022 256 Pfam PF13628 Domain of unknown function (DUF4142) 64 198 1.4E-17 T 06-07-2017 IPR025419 Domain of unknown function DUF4142 LK06_RS28150 3944ab06f1f39b59d039c4376dfc23db 692 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 18 126 5.8E-10 T 06-07-2017 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV LK06_RS28150 3944ab06f1f39b59d039c4376dfc23db 692 SUPERFAMILY SSF53649 161 447 1.7E-12 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 LK06_RS28150 3944ab06f1f39b59d039c4376dfc23db 692 Gene3D G3DSA:3.40.720.10 132 447 6.1E-13 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 LK06_RS28150 3944ab06f1f39b59d039c4376dfc23db 692 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 313 472 4.7E-7 T 06-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 LK06_RS09540 89bd64cbdaffc8d774f4ed1ba33328bb 131 SUPERFAMILY SSF54427 4 128 4.71E-23 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS09540 89bd64cbdaffc8d774f4ed1ba33328bb 131 Gene3D G3DSA:3.10.450.50 2 130 1.3E-28 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS09540 89bd64cbdaffc8d774f4ed1ba33328bb 131 Pfam PF12680 SnoaL-like domain 10 114 1.2E-14 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain LK06_RS11655 8383cad2c30ee32ba31579cb87a89688 508 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 52 197 3.3E-9 T 06-07-2017 LK06_RS21895 03635f5c74ddbf07809d61a7de85e668 330 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 53 88 2.6E-9 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LK06_RS21895 03635f5c74ddbf07809d61a7de85e668 330 SUPERFAMILY SSF161098 125 315 2.49E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21895 03635f5c74ddbf07809d61a7de85e668 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 146 330 1.7E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21895 03635f5c74ddbf07809d61a7de85e668 330 Gene3D G3DSA:1.10.3720.10 123 327 7.0E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS18350 c13d220515fbead68e9ab2089d385c1a 311 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 13 306 41.423 T 06-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 LK06_RS18350 c13d220515fbead68e9ab2089d385c1a 311 Gene3D G3DSA:3.40.50.10490 16 259 2.8E-81 T 06-07-2017 LK06_RS18350 c13d220515fbead68e9ab2089d385c1a 311 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 196 213 - T 06-07-2017 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 LK06_RS18350 c13d220515fbead68e9ab2089d385c1a 311 Pfam PF01380 SIS domain 126 219 3.8E-11 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 LK06_RS18350 c13d220515fbead68e9ab2089d385c1a 311 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 17 306 1.2E-110 T 06-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 LK06_RS18350 c13d220515fbead68e9ab2089d385c1a 311 SUPERFAMILY SSF53697 17 258 4.25E-66 T 06-07-2017 LK06_RS07660 8e11706e7c551509893ecf0ecab0ae13 462 SUPERFAMILY SSF64307 388 460 1.7E-16 T 06-07-2017 IPR001455 TusA-like domain LK06_RS07660 8e11706e7c551509893ecf0ecab0ae13 462 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 393 417 - T 06-07-2017 IPR001455 TusA-like domain LK06_RS07660 8e11706e7c551509893ecf0ecab0ae13 462 Gene3D G3DSA:3.90.1150.10 243 364 8.5E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS07660 8e11706e7c551509893ecf0ecab0ae13 462 Gene3D G3DSA:3.40.640.10 14 242 2.6E-57 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS07660 8e11706e7c551509893ecf0ecab0ae13 462 SUPERFAMILY SSF53383 3 366 1.34E-76 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS07660 8e11706e7c551509893ecf0ecab0ae13 462 Pfam PF00266 Aminotransferase class-V 3 358 5.1E-43 T 06-07-2017 IPR000192 Aminotransferase class V domain LK06_RS07660 8e11706e7c551509893ecf0ecab0ae13 462 Pfam PF01206 Sulfurtransferase TusA 392 459 5.4E-13 T 06-07-2017 IPR001455 TusA-like domain LK06_RS07660 8e11706e7c551509893ecf0ecab0ae13 462 Gene3D G3DSA:3.30.110.40 392 460 3.4E-18 T 06-07-2017 IPR001455 TusA-like domain LK06_RS08070 a1972d7c37f4a0f033ed562a129a53e8 301 PIRSF PIRSF007580 5 297 1.3E-122 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 LK06_RS08070 a1972d7c37f4a0f033ed562a129a53e8 301 Pfam PF10118 Predicted metal-dependent hydrolase 20 277 1.5E-79 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 LK06_RS06340 8e8a32b9fced78a9d660e8e220a91127 295 SUPERFAMILY SSF51197 29 294 4.58E-59 T 06-07-2017 LK06_RS06340 8e8a32b9fced78a9d660e8e220a91127 295 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 19 295 1.8E-152 T 06-07-2017 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 LK06_RS06340 8e8a32b9fced78a9d660e8e220a91127 295 Gene3D G3DSA:2.60.120.620 32 273 4.1E-51 T 06-07-2017 LK06_RS06340 8e8a32b9fced78a9d660e8e220a91127 295 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 43 258 1.6E-38 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase LK06_RS03195 62eec7f798a756cc6fb87f45b2999389 67 Pfam PF13701 Transposase DDE domain group 1 2 64 2.9E-10 T 06-07-2017 IPR025668 Transposase DDE domain LK06_RS04365 56146c58a3f424c6d600dc0914a77fb8 207 Pfam PF14280 Domain of unknown function (DUF4365) 34 200 2.3E-23 T 06-07-2017 IPR025375 Domain of unknown function DUF4365 LK06_RS20625 f3066b1da738e94f3a3126f7747bc3a3 312 Pfam PF03102 NeuB family 41 277 5.0E-82 T 06-07-2017 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 LK06_RS20625 f3066b1da738e94f3a3126f7747bc3a3 312 SUPERFAMILY SSF51569 10 290 2.69E-86 T 06-07-2017 LK06_RS20625 f3066b1da738e94f3a3126f7747bc3a3 312 Gene3D G3DSA:3.20.20.70 11 277 2.6E-100 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS01665 5b1f508853e77f98cfcce312804230ac 63 SUPERFAMILY SSF88659 2 49 2.4E-7 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS01665 5b1f508853e77f98cfcce312804230ac 63 Gene3D G3DSA:1.10.10.10 2 49 1.5E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00300 6b30fba8c7166acc56d4e653df8b793f 803 SUPERFAMILY SSF48208 275 782 1.5E-92 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS00300 6b30fba8c7166acc56d4e653df8b793f 803 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 322 734 2.7E-144 T 06-07-2017 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 LK06_RS00300 6b30fba8c7166acc56d4e653df8b793f 803 PIRSF PIRSF036289 6 803 9.3E-211 T 06-07-2017 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase LK06_RS00300 6b30fba8c7166acc56d4e653df8b793f 803 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 20 270 1.4E-62 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 LK06_RS00300 6b30fba8c7166acc56d4e653df8b793f 803 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 742 791 1.5E-8 T 06-07-2017 IPR005194 Glycoside hydrolase family 65, C-terminal LK06_RS00300 6b30fba8c7166acc56d4e653df8b793f 803 Gene3D G3DSA:2.70.98.40 14 272 4.2E-79 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 LK06_RS00300 6b30fba8c7166acc56d4e653df8b793f 803 Gene3D G3DSA:1.50.10.10 319 720 5.0E-122 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 LK06_RS00300 6b30fba8c7166acc56d4e653df8b793f 803 SUPERFAMILY SSF74650 13 271 1.85E-61 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 LK06_RS08740 194062e2b2b750f793569a39efe78cff 74 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 47 1.2E-15 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LK06_RS08740 194062e2b2b750f793569a39efe78cff 74 SMART SM00834 1 42 3.8E-13 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LK06_RS08740 194062e2b2b750f793569a39efe78cff 74 Pfam PF09723 Zinc ribbon domain 1 40 3.2E-12 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LK06_RS13285 5841fe605cfd0359975a2e56543c1bf6 48 SUPERFAMILY SSF63992 2 47 9.55E-12 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase LK06_RS13285 5841fe605cfd0359975a2e56543c1bf6 48 Gene3D G3DSA:3.40.50.10780 2 47 6.0E-12 T 06-07-2017 IPR027476 D-aminopeptidase, N-terminal LK06_RS13285 5841fe605cfd0359975a2e56543c1bf6 48 Pfam PF04951 D-aminopeptidase 2 47 1.4E-12 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase LK06_RS29315 5ce9e578f04cbd5201c55bcc0db862bb 131 SUPERFAMILY SSF69754 22 104 1.83E-5 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 LK06_RS29315 5ce9e578f04cbd5201c55bcc0db862bb 131 Gene3D G3DSA:3.10.450.50 11 88 4.6E-4 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS17455 6c00a81a9f127c4ec20b5644829ee83c 189 Gene3D G3DSA:1.10.357.10 3 186 1.7E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS17455 6c00a81a9f127c4ec20b5644829ee83c 189 SUPERFAMILY SSF48498 78 188 8.01E-13 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS17455 6c00a81a9f127c4ec20b5644829ee83c 189 SUPERFAMILY SSF46689 4 75 2.15E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS17455 6c00a81a9f127c4ec20b5644829ee83c 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17455 6c00a81a9f127c4ec20b5644829ee83c 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS17455 6c00a81a9f127c4ec20b5644829ee83c 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 3.3E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS25320 22a2a8ff14040f257df022e4ba019e02 182 Pfam PF04341 Protein of unknown function, DUF485 81 167 1.4E-26 T 06-07-2017 IPR007436 Protein of unknown function DUF485 LK06_RS08525 0e3f2fd706f20bdf9a48f11303d6be2d 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 303 1.4E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS08525 0e3f2fd706f20bdf9a48f11303d6be2d 315 SUPERFAMILY SSF161098 30 304 1.18E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS08525 0e3f2fd706f20bdf9a48f11303d6be2d 315 Gene3D G3DSA:1.10.3720.10 27 299 6.5E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS31410 8d191042ccd4bb8d107a222ba2491bdc 410 SUPERFAMILY SSF56524 268 409 1.12E-34 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS31410 8d191042ccd4bb8d107a222ba2491bdc 410 Pfam PF00174 Oxidoreductase molybdopterin binding domain 271 408 2.3E-22 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS31410 8d191042ccd4bb8d107a222ba2491bdc 410 Gene3D G3DSA:3.90.420.10 268 408 2.1E-31 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS21420 a4df2c52447f611e0ea2e5eddfac0d0e 795 Pfam PF00912 Transglycosylase 99 276 1.5E-57 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 LK06_RS21420 a4df2c52447f611e0ea2e5eddfac0d0e 795 Gene3D G3DSA:1.10.3810.10 100 278 1.4E-62 T 06-07-2017 LK06_RS21420 a4df2c52447f611e0ea2e5eddfac0d0e 795 SUPERFAMILY SSF56601 309 650 2.73E-74 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS21420 a4df2c52447f611e0ea2e5eddfac0d0e 795 SUPERFAMILY SSF56601 263 280 2.73E-74 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS21420 a4df2c52447f611e0ea2e5eddfac0d0e 795 Gene3D G3DSA:3.40.710.10 279 739 2.2E-88 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS21420 a4df2c52447f611e0ea2e5eddfac0d0e 795 SUPERFAMILY SSF53955 89 292 1.24E-61 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS21420 a4df2c52447f611e0ea2e5eddfac0d0e 795 Pfam PF00905 Penicillin binding protein transpeptidase domain 385 635 4.9E-38 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Gene3D G3DSA:2.30.38.10 347 429 6.5E-25 T 06-07-2017 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Gene3D G3DSA:3.40.50.1820 1026 1142 1.6E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Gene3D G3DSA:3.40.50.1820 1243 1308 1.6E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Pfam PF00550 Phosphopantetheine attachment site 954 1017 1.4E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 SUPERFAMILY SSF47336 945 1017 3.66E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Pfam PF00975 Thioesterase domain 1040 1137 2.6E-21 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 39 463 4.1E-123 T 06-07-2017 IPR010071 Amino acid adenylation domain LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 ProSitePatterns PS00012 Phosphopantetheine attachment site. 976 991 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 PRINTS PR00154 AMP-binding signature 185 193 6.4E-5 T 06-07-2017 IPR020459 AMP-binding LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 PRINTS PR00154 AMP-binding signature 173 184 6.4E-5 T 06-07-2017 IPR020459 AMP-binding LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Gene3D G3DSA:3.40.50.980 187 335 2.8E-43 T 06-07-2017 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 SUPERFAMILY SSF56801 885 962 2.09E-146 T 06-07-2017 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 SUPERFAMILY SSF56801 15 494 2.09E-146 T 06-07-2017 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Gene3D G3DSA:3.30.300.30 890 955 7.1E-26 T 06-07-2017 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Gene3D G3DSA:3.30.300.30 434 489 7.1E-26 T 06-07-2017 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 SUPERFAMILY SSF53474 1023 1306 1.26E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Gene3D G3DSA:1.10.1200.10 956 1022 1.6E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Pfam PF00501 AMP-binding enzyme 20 439 1.7E-102 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Gene3D G3DSA:3.40.50.980 163 186 6.1E-49 T 06-07-2017 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 Gene3D G3DSA:3.40.50.980 15 125 6.1E-49 T 06-07-2017 LK06_RS27175 be026d8a454acd5c608275c445df67d8 1326 SMART SM00823 Phosphopantetheine attachment site 952 1021 1.2E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LK06_RS06525 4d6d7cac8c2da2f97af86a5741ad9b92 323 Pfam PF01040 UbiA prenyltransferase family 50 306 6.9E-68 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 LK06_RS06525 4d6d7cac8c2da2f97af86a5741ad9b92 323 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 89 111 - T 06-07-2017 IPR030470 UbiA prenyltransferase conserved site LK06_RS06525 4d6d7cac8c2da2f97af86a5741ad9b92 323 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 34 321 19.462 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 LK06_RS06525 4d6d7cac8c2da2f97af86a5741ad9b92 323 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 36 319 4.9E-97 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 LK06_RS28920 8eca791649dfff9fb8e3685ed7020cfa 267 PIRSF PIRSF017393 2 265 5.3E-97 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS28920 8eca791649dfff9fb8e3685ed7020cfa 267 Pfam PF04672 S-adenosyl methyltransferase 7 265 3.5E-110 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS28920 8eca791649dfff9fb8e3685ed7020cfa 267 SUPERFAMILY SSF53335 14 246 1.08E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28920 8eca791649dfff9fb8e3685ed7020cfa 267 Gene3D G3DSA:3.40.50.150 6 265 4.5E-108 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 SUPERFAMILY SSF48019 262 445 6.8E-73 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 65 169 8.7E-14 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 Gene3D G3DSA:1.10.3710.10 358 445 5.1E-27 T 06-07-2017 LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 Gene3D G3DSA:1.10.8.60 178 242 1.5E-6 T 06-07-2017 LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 331 350 5.2E-5 T 06-07-2017 LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 69 88 5.2E-5 T 06-07-2017 LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 Pfam PF16193 AAA C-terminal domain 200 276 1.2E-24 T 06-07-2017 IPR032423 AAA ATPase, C-terminal domain LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 Gene3D G3DSA:3.40.50.300 11 170 1.2E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 SMART SM00382 61 182 6.7E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 SUPERFAMILY SSF52540 20 245 5.22E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 Pfam PF12002 MgsA AAA+ ATPase C terminal 277 441 7.2E-69 T 06-07-2017 IPR021886 MgsA AAA+ ATPase C-terminal LK06_RS04215 0f1f18c4395f1b5f4daaa1acf57e587f 451 Gene3D G3DSA:1.20.272.10 258 356 2.1E-45 T 06-07-2017 LK06_RS21360 3247e032b1ff7d05c087be294b4cee57 130 Pfam PF07883 Cupin domain 43 113 8.0E-14 T 06-07-2017 IPR013096 Cupin 2, conserved barrel LK06_RS21360 3247e032b1ff7d05c087be294b4cee57 130 SUPERFAMILY SSF51182 17 115 2.39E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS21360 3247e032b1ff7d05c087be294b4cee57 130 Gene3D G3DSA:2.60.120.10 12 126 4.4E-22 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS25410 4f218be305c6ae8e20f8641e903dc417 396 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 58 381 2.1E-42 T 06-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 LK06_RS25410 4f218be305c6ae8e20f8641e903dc417 396 Gene3D G3DSA:3.40.720.10 32 330 5.9E-45 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 LK06_RS25410 4f218be305c6ae8e20f8641e903dc417 396 SUPERFAMILY SSF53649 55 392 9.6E-58 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 LK06_RS23670 a30a79c35ed355e66c31bba260458fe9 240 SUPERFAMILY SSF53448 3 221 2.06E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS23670 a30a79c35ed355e66c31bba260458fe9 240 Pfam PF00535 Glycosyl transferase family 2 3 167 3.4E-16 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS23670 a30a79c35ed355e66c31bba260458fe9 240 Gene3D G3DSA:3.90.550.10 3 198 3.2E-15 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS12055 59bff365b18299e03c9bedc0c06db667 189 Gene3D G3DSA:3.30.565.10 94 181 2.6E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS12055 59bff365b18299e03c9bedc0c06db667 189 Pfam PF13581 Histidine kinase-like ATPase domain 71 181 2.3E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS12055 59bff365b18299e03c9bedc0c06db667 189 SUPERFAMILY SSF55874 93 183 4.19E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11160 02264c88d832ed733c3bb22ab2a804f1 245 Gene3D G3DSA:3.30.230.70 3 239 2.0E-32 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LK06_RS11160 02264c88d832ed733c3bb22ab2a804f1 245 Hamap MF_00564 Ribonuclease PH [rph]. 2 240 47.442 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 LK06_RS11160 02264c88d832ed733c3bb22ab2a804f1 245 Pfam PF03725 3' exoribonuclease family, domain 2 162 225 6.8E-10 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LK06_RS11160 02264c88d832ed733c3bb22ab2a804f1 245 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 06-07-2017 IPR018336 Ribonuclease PH, conserved site LK06_RS11160 02264c88d832ed733c3bb22ab2a804f1 245 Pfam PF01138 3' exoribonuclease family, domain 1 12 141 2.5E-25 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LK06_RS11160 02264c88d832ed733c3bb22ab2a804f1 245 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 239 7.3E-116 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 LK06_RS11160 02264c88d832ed733c3bb22ab2a804f1 245 SUPERFAMILY SSF54211 3 183 3.09E-46 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS11160 02264c88d832ed733c3bb22ab2a804f1 245 SUPERFAMILY SSF55666 156 241 1.28E-24 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LK06_RS04580 4c3370f126c54395f32d76b4a0684678 212 SUPERFAMILY SSF55729 7 175 3.23E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS04580 4c3370f126c54395f32d76b4a0684678 212 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 3.2E-26 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS04580 4c3370f126c54395f32d76b4a0684678 212 Gene3D G3DSA:3.40.630.30 7 193 1.3E-47 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS02240 65403a2e981ef846c6c15155748c7c2e 412 SUPERFAMILY SSF53623 226 279 2.88E-29 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS02240 65403a2e981ef846c6c15155748c7c2e 412 SUPERFAMILY SSF53623 51 196 2.88E-29 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS02240 65403a2e981ef846c6c15155748c7c2e 412 Gene3D G3DSA:3.40.1190.10 47 284 5.4E-38 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS02240 65403a2e981ef846c6c15155748c7c2e 412 Pfam PF08353 Domain of unknown function (DUF1727) 304 403 4.2E-22 T 06-07-2017 IPR013564 Domain of unknown function DUF1727 LK06_RS02240 65403a2e981ef846c6c15155748c7c2e 412 Pfam PF08245 Mur ligase middle domain 65 266 2.6E-11 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 SUPERFAMILY SSF53720 19 435 1.41E-70 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 PIRSF PIRSF000099 5 436 2.8E-160 T 06-07-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 06-07-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 6.2E-83 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 6.2E-83 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 PRINTS PR00083 Histidinol dehydrogenase signature 367 385 6.2E-83 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 6.2E-83 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 PRINTS PR00083 Histidinol dehydrogenase signature 326 351 6.2E-83 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 6.2E-83 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 6.2E-83 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 6.2E-83 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 Pfam PF00815 Histidinol dehydrogenase 24 433 2.0E-153 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 433 38.445 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 432 5.2E-139 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LK06_RS07155 a82e88c33b3531fc39720e66ab828f10 441 Gene3D G3DSA:3.40.50.1980 30 243 1.5E-75 T 06-07-2017 LK06_RS30510 838a6958a5b6b85f694a5c6334f1678b 481 Pfam PF00083 Sugar (and other) transporter 62 448 7.9E-35 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 LK06_RS30510 838a6958a5b6b85f694a5c6334f1678b 481 Gene3D G3DSA:1.20.1250.20 267 445 1.7E-17 T 06-07-2017 LK06_RS30510 838a6958a5b6b85f694a5c6334f1678b 481 Gene3D G3DSA:1.20.1250.20 27 212 7.5E-27 T 06-07-2017 LK06_RS30510 838a6958a5b6b85f694a5c6334f1678b 481 SUPERFAMILY SSF103473 14 443 4.58E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS30510 838a6958a5b6b85f694a5c6334f1678b 481 ProSitePatterns PS00216 Sugar transport proteins signature 1. 82 98 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LK06_RS06130 8ed762119a682cb84455af1d3ab61a70 265 Pfam PF02104 SURF1 family 22 231 1.3E-29 T 06-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS28185 80270164e50ef9fa20a64070f13d3dbb 249 Pfam PF08241 Methyltransferase domain 40 134 4.5E-20 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS28185 80270164e50ef9fa20a64070f13d3dbb 249 SUPERFAMILY SSF53335 4 227 3.16E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28185 80270164e50ef9fa20a64070f13d3dbb 249 Gene3D G3DSA:3.40.50.150 4 137 3.2E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS31055 5fc1f2118225322f15af571c814c814e 509 Pfam PF00149 Calcineurin-like phosphoesterase 87 178 2.8E-6 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 LK06_RS31055 5fc1f2118225322f15af571c814c814e 509 SUPERFAMILY SSF56300 212 344 8.59E-28 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS31055 5fc1f2118225322f15af571c814c814e 509 SUPERFAMILY SSF56300 85 182 8.59E-28 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS31055 5fc1f2118225322f15af571c814c814e 509 Gene3D G3DSA:3.60.21.10 84 161 8.5E-27 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS31055 5fc1f2118225322f15af571c814c814e 509 Gene3D G3DSA:3.60.21.10 206 371 8.5E-27 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS17555 70be802086238786127ec2f903818511 308 Pfam PF00583 Acetyltransferase (GNAT) family 218 295 1.5E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS17555 70be802086238786127ec2f903818511 308 Pfam PF00583 Acetyltransferase (GNAT) family 68 137 8.2E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS17555 70be802086238786127ec2f903818511 308 SUPERFAMILY SSF55729 17 304 1.33E-49 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS17555 70be802086238786127ec2f903818511 308 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 15 306 36.821 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 LK06_RS17555 70be802086238786127ec2f903818511 308 Gene3D G3DSA:3.40.630.30 165 304 7.6E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS17555 70be802086238786127ec2f903818511 308 Gene3D G3DSA:3.40.630.30 20 143 4.3E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS17555 70be802086238786127ec2f903818511 308 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 17 304 5.5E-119 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 LK06_RS17555 70be802086238786127ec2f903818511 308 PIRSF PIRSF021524 9 308 1.1E-112 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 LK06_RS01125 e5da3f125c04d737dd54b781b4aadc80 236 Pfam PF14016 Protein of unknown function (DUF4232) 101 218 1.4E-33 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 LK06_RS09965 14257af2b057f60c01b8b77aecf86860 112 Pfam PF13551 Winged helix-turn helix 52 104 6.5E-10 T 06-07-2017 LK06_RS09965 14257af2b057f60c01b8b77aecf86860 112 SUPERFAMILY SSF46689 37 101 4.3E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01315 5a6cecd30887b3e879af6dba78ed08b7 450 SUPERFAMILY SSF53300 278 409 3.61E-8 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS01315 5a6cecd30887b3e879af6dba78ed08b7 450 PIRSF PIRSF010256 2 450 4.4E-126 T 06-07-2017 IPR011195 Uncharacterised conserved protein UCP010256 LK06_RS01315 5a6cecd30887b3e879af6dba78ed08b7 450 Pfam PF05762 VWA domain containing CoxE-like protein 222 441 3.3E-50 T 06-07-2017 IPR008912 Uncharacterised protein family CoxE-like LK06_RS18385 396c2d9bac289893bb048380badadf5c 123 SUPERFAMILY SSF47090 45 111 6.8E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18385 396c2d9bac289893bb048380badadf5c 123 Gene3D G3DSA:1.10.101.10 44 112 1.1E-20 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18385 396c2d9bac289893bb048380badadf5c 123 Pfam PF01471 Putative peptidoglycan binding domain 52 109 1.8E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS11575 e5f2d93a02138b7f4ef69d0974ee3238 305 PIRSF PIRSF003097 1 305 7.4E-75 T 06-07-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 LK06_RS11575 e5f2d93a02138b7f4ef69d0974ee3238 305 Pfam PF02687 FtsX-like permease family 184 304 1.2E-9 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS02285 9ffa23b628522f8c041f9444d0eff7b8 521 Pfam PF00561 alpha/beta hydrolase fold 103 481 3.1E-28 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS02285 9ffa23b628522f8c041f9444d0eff7b8 521 Gene3D G3DSA:3.40.50.1820 381 501 8.9E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02285 9ffa23b628522f8c041f9444d0eff7b8 521 Gene3D G3DSA:3.40.50.1820 67 155 8.9E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02285 9ffa23b628522f8c041f9444d0eff7b8 521 Gene3D G3DSA:3.40.50.1820 199 325 8.9E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02285 9ffa23b628522f8c041f9444d0eff7b8 521 SUPERFAMILY SSF53474 85 156 6.17E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02285 9ffa23b628522f8c041f9444d0eff7b8 521 SUPERFAMILY SSF53474 201 255 6.17E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02285 9ffa23b628522f8c041f9444d0eff7b8 521 SUPERFAMILY SSF53474 334 501 6.17E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS31460 e06623fc5df8ec368e19598fe4641d05 232 SUPERFAMILY SSF49899 23 214 2.16E-14 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain LK06_RS31460 e06623fc5df8ec368e19598fe4641d05 232 Pfam PF00722 Glycosyl hydrolases family 16 101 190 1.3E-4 T 06-07-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 LK06_RS31460 e06623fc5df8ec368e19598fe4641d05 232 Gene3D G3DSA:2.60.120.200 69 170 3.5E-13 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain LK06_RS04020 b8646b145f7740707e44502b94d23d93 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 274 2.3E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS04020 b8646b145f7740707e44502b94d23d93 303 SUPERFAMILY SSF161098 24 298 8.22E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS04020 b8646b145f7740707e44502b94d23d93 303 Gene3D G3DSA:1.10.3720.10 22 291 9.9E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS15560 0b426de3b64cf495def214a2c0e5ced9 279 SMART SM00240 205 254 9.0E-11 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS15560 0b426de3b64cf495def214a2c0e5ced9 279 Pfam PF00498 FHA domain 207 268 1.7E-14 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS15560 0b426de3b64cf495def214a2c0e5ced9 279 SUPERFAMILY SSF49879 164 275 1.86E-22 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS15560 0b426de3b64cf495def214a2c0e5ced9 279 Gene3D G3DSA:2.60.200.20 195 275 5.6E-24 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS15560 0b426de3b64cf495def214a2c0e5ced9 279 Pfam PF12401 Protein of unknown function (DUF2662) 4 118 6.3E-42 T 06-07-2017 IPR022128 Protein of unknown function DUF3662 LK06_RS28645 84a77c074a6c0257319499bddc55040c 302 Gene3D G3DSA:3.40.1190.20 6 298 5.7E-47 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS28645 84a77c074a6c0257319499bddc55040c 302 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 241 254 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 LK06_RS28645 84a77c074a6c0257319499bddc55040c 302 Pfam PF00294 pfkB family carbohydrate kinase 183 281 3.8E-18 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB LK06_RS28645 84a77c074a6c0257319499bddc55040c 302 SUPERFAMILY SSF53613 6 296 7.02E-47 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS12150 fca9263d54be649df494b7d8b1cdfcbb 170 Pfam PF00380 Ribosomal protein S9/S16 49 170 2.9E-43 T 06-07-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 LK06_RS12150 fca9263d54be649df494b7d8b1cdfcbb 170 ProSitePatterns PS00360 Ribosomal protein S9 signature. 108 126 - T 06-07-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 LK06_RS12150 fca9263d54be649df494b7d8b1cdfcbb 170 SUPERFAMILY SSF54211 46 170 4.17E-42 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS12150 fca9263d54be649df494b7d8b1cdfcbb 170 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 40 170 32.58 T 06-07-2017 IPR023035 Ribosomal protein S9, bacterial/plastid LK06_RS12150 fca9263d54be649df494b7d8b1cdfcbb 170 Gene3D G3DSA:3.30.230.10 46 170 7.6E-47 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS30600 f9b300fb6bcef9e437ec8b39914f81e6 356 SUPERFAMILY SSF53901 9 226 2.88E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS30600 f9b300fb6bcef9e437ec8b39914f81e6 356 Gene3D G3DSA:3.40.47.10 20 136 5.4E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS30600 f9b300fb6bcef9e437ec8b39914f81e6 356 Gene3D G3DSA:3.40.47.10 201 222 5.4E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS30600 f9b300fb6bcef9e437ec8b39914f81e6 356 Gene3D G3DSA:3.40.47.10 253 336 5.1E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS30600 f9b300fb6bcef9e437ec8b39914f81e6 356 SUPERFAMILY SSF53901 229 343 2.62E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS27885 1416c335d10bb894751ddd3bb3b2585a 469 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 55 9.6E-12 T 06-07-2017 LK06_RS27885 1416c335d10bb894751ddd3bb3b2585a 469 SUPERFAMILY SSF51905 2 297 4.32E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27885 1416c335d10bb894751ddd3bb3b2585a 469 SUPERFAMILY SSF51905 424 466 4.32E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27885 1416c335d10bb894751ddd3bb3b2585a 469 Gene3D G3DSA:3.50.50.60 300 340 2.4E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27885 1416c335d10bb894751ddd3bb3b2585a 469 Gene3D G3DSA:3.40.50.720 3 53 4.8E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27885 1416c335d10bb894751ddd3bb3b2585a 469 Gene3D G3DSA:3.50.50.60 433 467 5.2E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27885 1416c335d10bb894751ddd3bb3b2585a 469 Gene3D G3DSA:3.50.50.60 204 285 5.2E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27885 1416c335d10bb894751ddd3bb3b2585a 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 285 306 1.9E-6 T 06-07-2017 LK06_RS27885 1416c335d10bb894751ddd3bb3b2585a 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.9E-6 T 06-07-2017 LK06_RS02400 db380fb91ced0e82e9e78637e7bb37ce 84 SUPERFAMILY SSF47598 4 46 8.9E-6 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 LK06_RS03395 6a1e9fa8eb209c1a24b411bad2be73a0 572 Pfam PF00665 Integrase core domain 348 416 1.3E-8 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 LK06_RS03395 6a1e9fa8eb209c1a24b411bad2be73a0 572 Pfam PF09299 Mu transposase, C-terminal 506 567 7.2E-7 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal LK06_RS03395 6a1e9fa8eb209c1a24b411bad2be73a0 572 SUPERFAMILY SSF53098 361 468 1.42E-11 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03395 6a1e9fa8eb209c1a24b411bad2be73a0 572 SUPERFAMILY SSF53098 259 326 1.42E-11 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03395 6a1e9fa8eb209c1a24b411bad2be73a0 572 Gene3D G3DSA:3.30.420.10 357 468 8.7E-21 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03395 6a1e9fa8eb209c1a24b411bad2be73a0 572 Gene3D G3DSA:3.30.420.10 263 319 8.7E-21 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS28195 9bcef21afd5c1cbcffa32ee907ce8a98 308 Pfam PF13649 Methyltransferase domain 68 165 2.1E-11 T 06-07-2017 LK06_RS28195 9bcef21afd5c1cbcffa32ee907ce8a98 308 SUPERFAMILY SSF53335 47 240 2.15E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28195 9bcef21afd5c1cbcffa32ee907ce8a98 308 Gene3D G3DSA:3.40.50.150 52 257 5.9E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS14145 ba99124b4e3ba3d5d78cc6e42c6bdf32 294 Gene3D G3DSA:3.90.79.10 23 216 1.8E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS14145 ba99124b4e3ba3d5d78cc6e42c6bdf32 294 SUPERFAMILY SSF55811 25 77 6.84E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS14145 ba99124b4e3ba3d5d78cc6e42c6bdf32 294 SUPERFAMILY SSF55811 158 237 6.84E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS14145 ba99124b4e3ba3d5d78cc6e42c6bdf32 294 SUPERFAMILY SSF55811 105 116 6.84E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS01800 b420e15ae7b2308ab738ac8561f196ee 487 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 47 297 2.2E-34 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 LK06_RS01800 b420e15ae7b2308ab738ac8561f196ee 487 SUPERFAMILY SSF52777 69 187 1.33E-6 T 06-07-2017 LK06_RS01800 b420e15ae7b2308ab738ac8561f196ee 487 Pfam PF06974 Protein of unknown function (DUF1298) 338 478 7.5E-23 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 LK06_RS15090 dbd3af51ac8c449d49f1d5f64e47870e 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 3.2E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS15090 dbd3af51ac8c449d49f1d5f64e47870e 214 SUPERFAMILY SSF46689 2 76 8.21E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS15090 dbd3af51ac8c449d49f1d5f64e47870e 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS15090 dbd3af51ac8c449d49f1d5f64e47870e 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS15090 dbd3af51ac8c449d49f1d5f64e47870e 214 Gene3D G3DSA:1.10.357.10 2 203 1.5E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS13810 ac7e2ee4e3cfdc1b60fad06441700a07 365 Pfam PF09179 TilS substrate binding domain 293 360 5.6E-11 T 06-07-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 LK06_RS13810 ac7e2ee4e3cfdc1b60fad06441700a07 365 SUPERFAMILY SSF52402 66 276 9.43E-46 T 06-07-2017 LK06_RS13810 ac7e2ee4e3cfdc1b60fad06441700a07 365 Gene3D G3DSA:3.40.50.620 66 226 5.7E-12 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS13810 ac7e2ee4e3cfdc1b60fad06441700a07 365 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 58 354 20.195 T 06-07-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 LK06_RS13810 ac7e2ee4e3cfdc1b60fad06441700a07 365 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 66 247 8.0E-43 T 06-07-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 LK06_RS13810 ac7e2ee4e3cfdc1b60fad06441700a07 365 SUPERFAMILY SSF82829 256 360 1.83E-15 T 06-07-2017 LK06_RS13810 ac7e2ee4e3cfdc1b60fad06441700a07 365 Pfam PF01171 PP-loop family 66 244 5.1E-38 T 06-07-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 LK06_RS04025 8dccad27bace11a3fc57245f8db4878e 385 Gene3D G3DSA:3.40.190.10 11 164 9.3E-27 T 06-07-2017 LK06_RS04025 8dccad27bace11a3fc57245f8db4878e 385 Gene3D G3DSA:3.40.190.10 310 348 9.3E-27 T 06-07-2017 LK06_RS04025 8dccad27bace11a3fc57245f8db4878e 385 Gene3D G3DSA:3.40.190.10 167 309 3.8E-23 T 06-07-2017 LK06_RS04025 8dccad27bace11a3fc57245f8db4878e 385 SUPERFAMILY SSF53850 64 350 1.19E-50 T 06-07-2017 LK06_RS04025 8dccad27bace11a3fc57245f8db4878e 385 Pfam PF13343 Bacterial extracellular solute-binding protein 118 346 6.7E-37 T 06-07-2017 LK06_RS01050 7741fe4d319e2533f076d74827371642 265 Gene3D G3DSA:3.20.20.370 48 240 2.6E-46 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS01050 7741fe4d319e2533f076d74827371642 265 Pfam PF01522 Polysaccharide deacetylase 50 167 2.1E-28 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS01050 7741fe4d319e2533f076d74827371642 265 SUPERFAMILY SSF88713 43 242 5.56E-50 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 2.2E-25 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 Pfam PF00361 Proton-conducting membrane transporter 135 422 2.3E-82 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 6.4E-60 T 06-07-2017 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 6.4E-60 T 06-07-2017 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 6.4E-60 T 06-07-2017 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 6.4E-60 T 06-07-2017 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 6.4E-60 T 06-07-2017 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 6.4E-60 T 06-07-2017 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 6.4E-60 T 06-07-2017 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 3.6E-11 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 420 442 3.6E-11 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 3.6E-11 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 264 286 3.6E-11 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LK06_RS12900 3bd925d61a9e21e9026322e84d7ea8de 642 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 636 4.8E-235 T 06-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS31800 0571badcffde511c1e0450c96938e9b6 320 Pfam PF02779 Transketolase, pyrimidine binding domain 5 172 1.4E-31 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS31800 0571badcffde511c1e0450c96938e9b6 320 Gene3D G3DSA:3.40.50.970 4 190 1.5E-53 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS31800 0571badcffde511c1e0450c96938e9b6 320 SUPERFAMILY SSF52922 187 319 2.75E-28 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS31800 0571badcffde511c1e0450c96938e9b6 320 SUPERFAMILY SSF52518 2 201 1.01E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS31800 0571badcffde511c1e0450c96938e9b6 320 SMART SM00861 4 177 8.9E-41 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain LK06_RS31800 0571badcffde511c1e0450c96938e9b6 320 Pfam PF02780 Transketolase, C-terminal domain 191 309 2.1E-27 T 06-07-2017 IPR033248 Transketolase, C-terminal domain LK06_RS31800 0571badcffde511c1e0450c96938e9b6 320 Gene3D G3DSA:3.40.50.920 191 319 1.2E-29 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 LK06_RS26255 49e9fd102a24dfa764fd21c13a3a5251 285 Gene3D G3DSA:3.40.50.150 62 199 1.5E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26255 49e9fd102a24dfa764fd21c13a3a5251 285 SUPERFAMILY SSF53335 10 282 2.85E-62 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26255 49e9fd102a24dfa764fd21c13a3a5251 285 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 265 1.1E-50 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 LK06_RS26255 49e9fd102a24dfa764fd21c13a3a5251 285 Pfam PF04072 Leucine carboxyl methyltransferase 13 189 4.8E-50 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 LK06_RS30725 0c0c0eab9aad5bef7fbc8473bdbf1357 126 Pfam PF03965 Penicillinase repressor 12 122 5.8E-24 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 LK06_RS30725 0c0c0eab9aad5bef7fbc8473bdbf1357 126 SUPERFAMILY SSF46785 13 122 1.37E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30725 0c0c0eab9aad5bef7fbc8473bdbf1357 126 Gene3D G3DSA:1.10.10.10 14 79 7.9E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11635 15b4de8e973117b403d58428816dc9ca 749 Pfam PF00535 Glycosyl transferase family 2 60 128 1.7E-10 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS11635 15b4de8e973117b403d58428816dc9ca 749 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 357 720 1.7E-126 T 06-07-2017 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 LK06_RS11635 15b4de8e973117b403d58428816dc9ca 749 Gene3D G3DSA:3.90.550.10 2 229 1.3E-26 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11635 15b4de8e973117b403d58428816dc9ca 749 SUPERFAMILY SSF53756 519 719 6.91E-7 T 06-07-2017 LK06_RS11635 15b4de8e973117b403d58428816dc9ca 749 SUPERFAMILY SSF53448 1 231 1.2E-30 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS28570 6c2b7e3650d04162dcdaaca7a4582d2c 324 SUPERFAMILY SSF47240 12 319 2.3E-81 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS28570 6c2b7e3650d04162dcdaaca7a4582d2c 324 Pfam PF03405 Fatty acid desaturase 18 317 1.0E-75 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 LK06_RS28570 6c2b7e3650d04162dcdaaca7a4582d2c 324 PIRSF PIRSF000346 1 323 3.9E-113 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 LK06_RS28570 6c2b7e3650d04162dcdaaca7a4582d2c 324 Gene3D G3DSA:1.10.620.20 11 313 2.4E-107 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 LK06_RS19340 1b9e7dce01784b8f18076200c2a4a32c 277 Pfam PF01048 Phosphorylase superfamily 6 247 6.4E-41 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS19340 1b9e7dce01784b8f18076200c2a4a32c 277 SUPERFAMILY SSF53167 5 262 3.26E-83 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS19340 1b9e7dce01784b8f18076200c2a4a32c 277 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 6 250 3.7E-87 T 06-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 LK06_RS19340 1b9e7dce01784b8f18076200c2a4a32c 277 Gene3D G3DSA:3.40.50.1580 3 265 4.5E-83 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS19340 1b9e7dce01784b8f18076200c2a4a32c 277 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 4 272 41.805 T 06-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 LK06_RS14080 c79a6640af6cc67e0afef6799d8926a4 421 Gene3D G3DSA:3.20.20.370 80 380 5.4E-11 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS14080 c79a6640af6cc67e0afef6799d8926a4 421 SUPERFAMILY SSF88713 148 379 1.24E-24 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS14080 c79a6640af6cc67e0afef6799d8926a4 421 SUPERFAMILY SSF88713 76 118 1.24E-24 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS31745 7b09df6523c5cd4ad777f936279e13f6 385 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 253 259 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 LK06_RS31745 7b09df6523c5cd4ad777f936279e13f6 385 PIRSF PIRSF000138 1 359 4.9E-126 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 LK06_RS31745 7b09df6523c5cd4ad777f936279e13f6 385 SUPERFAMILY SSF51395 4 353 8.37E-95 T 06-07-2017 LK06_RS31745 7b09df6523c5cd4ad777f936279e13f6 385 Pfam PF01070 FMN-dependent dehydrogenase 13 356 3.6E-125 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 LK06_RS31745 7b09df6523c5cd4ad777f936279e13f6 385 Gene3D G3DSA:3.20.20.70 3 357 4.1E-131 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS30270 9ce9552c533f29542bc62a2a645f6b4a 155 Pfam PF09851 Short C-terminal domain 110 136 7.4E-8 T 06-07-2017 IPR018649 SHOCT domain LK06_RS30270 9ce9552c533f29542bc62a2a645f6b4a 155 Pfam PF13396 Phospholipase_D-nuclease N-terminal 27 73 6.1E-6 T 06-07-2017 IPR027379 Cardiolipin synthase N-terminal LK06_RS23565 f38939a2f9b22fa04b919a22c4dde692 242 Gene3D G3DSA:1.10.260.40 90 147 2.4E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS23565 f38939a2f9b22fa04b919a22c4dde692 242 Gene3D G3DSA:1.10.260.40 24 86 2.1E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS23565 f38939a2f9b22fa04b919a22c4dde692 242 SMART SM00530 22 84 0.16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS23565 f38939a2f9b22fa04b919a22c4dde692 242 SMART SM00530 90 146 0.021 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS10360 11bc4e9a053a95137a62b88cd285555d 230 Pfam PF01522 Polysaccharide deacetylase 49 183 5.8E-29 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS10360 11bc4e9a053a95137a62b88cd285555d 230 SUPERFAMILY SSF88713 13 185 8.16E-39 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS10360 11bc4e9a053a95137a62b88cd285555d 230 Gene3D G3DSA:3.20.20.370 49 186 1.8E-29 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS09395 7fc637556612fc8b393540b182d73aca 320 SUPERFAMILY SSF54814 201 320 1.37E-34 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 LK06_RS09395 7fc637556612fc8b393540b182d73aca 320 TIGRFAM TIGR00436 era: GTP-binding protein Era 22 303 5.0E-65 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 LK06_RS09395 7fc637556612fc8b393540b182d73aca 320 Gene3D G3DSA:3.30.300.20 211 316 4.4E-36 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS09395 7fc637556612fc8b393540b182d73aca 320 Gene3D G3DSA:3.40.50.300 25 210 5.0E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09395 7fc637556612fc8b393540b182d73aca 320 Hamap MF_00367 GTPase Era [era]. 19 320 34.333 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 LK06_RS09395 7fc637556612fc8b393540b182d73aca 320 Pfam PF01926 50S ribosome-binding GTPase 25 138 3.5E-20 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 LK06_RS09395 7fc637556612fc8b393540b182d73aca 320 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 26 150 4.6E-16 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 LK06_RS09395 7fc637556612fc8b393540b182d73aca 320 Pfam PF07650 KH domain 227 309 1.1E-15 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LK06_RS09395 7fc637556612fc8b393540b182d73aca 320 SUPERFAMILY SSF52540 25 232 1.18E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01360 7876f5017b12530eae69d77e2306da97 344 Gene3D G3DSA:3.90.180.10 1 168 1.7E-42 T 06-07-2017 IPR011032 GroES-like LK06_RS01360 7876f5017b12530eae69d77e2306da97 344 Gene3D G3DSA:3.40.50.720 169 302 1.1E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01360 7876f5017b12530eae69d77e2306da97 344 SUPERFAMILY SSF51735 147 310 6.91E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS01360 7876f5017b12530eae69d77e2306da97 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 126 1.6E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LK06_RS01360 7876f5017b12530eae69d77e2306da97 344 Pfam PF00107 Zinc-binding dehydrogenase 177 289 2.0E-16 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LK06_RS01360 7876f5017b12530eae69d77e2306da97 344 SUPERFAMILY SSF50129 1 176 8.67E-51 T 06-07-2017 IPR011032 GroES-like LK06_RS05475 b4eab8f2c30f8bd9aaac29e538ff91a3 364 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 182 312 6.6E-11 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS05475 b4eab8f2c30f8bd9aaac29e538ff91a3 364 Gene3D G3DSA:3.40.50.300 180 306 3.5E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05475 b4eab8f2c30f8bd9aaac29e538ff91a3 364 SUPERFAMILY SSF52540 172 315 7.72E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05475 b4eab8f2c30f8bd9aaac29e538ff91a3 364 SMART SM00382 178 315 5.9E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS30365 b283478bd1b89c4fb7b55e756c68aa45 467 Pfam PF09594 Protein of unknown function (DUF2029) 71 301 4.0E-50 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 Pfam PF05593 RHS Repeat 643 672 6.8E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 Pfam PF05593 RHS Repeat 429 462 4.7E-10 T 06-07-2017 IPR031325 RHS repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 Pfam PF05593 RHS Repeat 468 503 1.2E-6 T 06-07-2017 IPR031325 RHS repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 Pfam PF05593 RHS Repeat 529 563 5.3E-5 T 06-07-2017 IPR031325 RHS repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 Pfam PF05593 RHS Repeat 687 724 1.7E-11 T 06-07-2017 IPR031325 RHS repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 Pfam PF05593 RHS Repeat 729 758 4.1E-7 T 06-07-2017 IPR031325 RHS repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 Pfam PF05593 RHS Repeat 708 744 5.0E-13 T 06-07-2017 IPR031325 RHS repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 Pfam PF05593 RHS Repeat 573 609 3.2E-6 T 06-07-2017 IPR031325 RHS repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 Pfam PF05593 RHS Repeat 615 651 5.2E-10 T 06-07-2017 IPR031325 RHS repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 729 758 1.9E-7 T 06-07-2017 IPR006530 YD repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 619 656 9.9E-9 T 06-07-2017 IPR006530 YD repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 369 405 1.8E-4 T 06-07-2017 IPR006530 YD repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 468 505 7.6E-4 T 06-07-2017 IPR006530 YD repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 573 614 1.2E-7 T 06-07-2017 IPR006530 YD repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 636 673 1.5E-9 T 06-07-2017 IPR006530 YD repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 428 461 5.1E-8 T 06-07-2017 IPR006530 YD repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 657 706 2.7E-6 T 06-07-2017 IPR006530 YD repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 529 562 2.1E-5 T 06-07-2017 IPR006530 YD repeat LK06_RS18045 14bc6e1f95267d6fdebc718cafbdf1e2 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 708 746 6.9E-12 T 06-07-2017 IPR006530 YD repeat LK06_RS29495 1f513843ce8cec71ce0c1d2d7db93234 221 SUPERFAMILY SSF52833 54 217 7.33E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS29495 1f513843ce8cec71ce0c1d2d7db93234 221 Gene3D G3DSA:3.40.30.10 16 218 1.2E-42 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS29495 1f513843ce8cec71ce0c1d2d7db93234 221 Pfam PF02630 SCO1/SenC 58 184 1.2E-24 T 06-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS24980 439f3459b719f3b1e156fab5fb18a646 279 Pfam PF13413 Helix-turn-helix domain 28 87 5.6E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS24980 439f3459b719f3b1e156fab5fb18a646 279 Pfam PF13464 Domain of unknown function (DUF4115) 202 270 4.9E-15 T 06-07-2017 IPR025194 Domain of unknown function DUF4115 LK06_RS12650 c72552288c0911a42edc05c41124ee10 124 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 106 19.045 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 LK06_RS12650 c72552288c0911a42edc05c41124ee10 124 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 101 1.5E-28 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 LK06_RS03110 7b0a9ce1a2b1528cedfc9a320edb1988 524 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 66 444 2.2E-88 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 LK06_RS03110 7b0a9ce1a2b1528cedfc9a320edb1988 524 Pfam PF00795 Carbon-nitrogen hydrolase 220 447 5.4E-23 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS03110 7b0a9ce1a2b1528cedfc9a320edb1988 524 SUPERFAMILY SSF56317 218 478 1.1E-42 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS03110 7b0a9ce1a2b1528cedfc9a320edb1988 524 Gene3D G3DSA:3.60.110.10 216 474 1.7E-33 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS03110 7b0a9ce1a2b1528cedfc9a320edb1988 524 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 11 483 16.865 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 LK06_RS05500 6e44936e81ba872bf933be16c24f7b44 201 SUPERFAMILY SSF53335 12 156 1.23E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS05500 6e44936e81ba872bf933be16c24f7b44 201 Pfam PF08241 Methyltransferase domain 52 145 1.0E-21 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS05500 6e44936e81ba872bf933be16c24f7b44 201 Gene3D G3DSA:3.40.50.150 12 158 8.2E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25565 8becbd884031709b44ba81e256b046e6 1249 Pfam PF00271 Helicase conserved C-terminal domain 992 1037 3.4E-6 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS25565 8becbd884031709b44ba81e256b046e6 1249 SUPERFAMILY SSF52540 500 567 2.19E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25565 8becbd884031709b44ba81e256b046e6 1249 SUPERFAMILY SSF52540 956 1078 2.19E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25565 8becbd884031709b44ba81e256b046e6 1249 Gene3D G3DSA:3.40.50.300 940 1062 5.3E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23725 efedae631df162abb0281b2874edd042 347 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 43 214 2.7E-11 T 06-07-2017 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent LK06_RS23725 efedae631df162abb0281b2874edd042 347 SUPERFAMILY SSF51695 32 221 9.42E-12 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS27445 3eac123bea796f6b1b8fefa08bbae9f8 212 Gene3D G3DSA:3.30.1050.10 143 206 6.1E-6 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS27445 3eac123bea796f6b1b8fefa08bbae9f8 212 SUPERFAMILY SSF55718 143 209 3.3E-9 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS27445 3eac123bea796f6b1b8fefa08bbae9f8 212 Gene3D G3DSA:1.10.10.10 5 108 3.3E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27445 3eac123bea796f6b1b8fefa08bbae9f8 212 SUPERFAMILY SSF46785 7 115 6.68E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27445 3eac123bea796f6b1b8fefa08bbae9f8 212 Pfam PF02036 SCP-2 sterol transfer family 136 209 4.6E-6 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS27445 3eac123bea796f6b1b8fefa08bbae9f8 212 Pfam PF01638 HxlR-like helix-turn-helix 19 105 1.6E-22 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type LK06_RS16980 d4808127947c7576838ca07e5010affc 204 Gene3D G3DSA:3.40.50.2300 4 123 3.0E-33 T 06-07-2017 LK06_RS16980 d4808127947c7576838ca07e5010affc 204 SMART SM00448 5 118 2.5E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS16980 d4808127947c7576838ca07e5010affc 204 SUPERFAMILY SSF46894 128 204 2.65E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS16980 d4808127947c7576838ca07e5010affc 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 198 4.0E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS16980 d4808127947c7576838ca07e5010affc 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 1.4E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS16980 d4808127947c7576838ca07e5010affc 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 1.4E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS16980 d4808127947c7576838ca07e5010affc 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 1.4E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS16980 d4808127947c7576838ca07e5010affc 204 SMART SM00421 141 198 1.5E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS16980 d4808127947c7576838ca07e5010affc 204 Gene3D G3DSA:1.10.10.10 124 204 5.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16980 d4808127947c7576838ca07e5010affc 204 SUPERFAMILY SSF52172 4 132 2.56E-31 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS16980 d4808127947c7576838ca07e5010affc 204 Pfam PF00072 Response regulator receiver domain 8 118 8.4E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS23985 d7d534f78de147da34a347f37ec47e09 151 SUPERFAMILY SSF55874 27 133 5.08E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23985 d7d534f78de147da34a347f37ec47e09 151 Pfam PF13581 Histidine kinase-like ATPase domain 19 132 5.9E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23985 d7d534f78de147da34a347f37ec47e09 151 Gene3D G3DSA:3.30.565.10 35 133 1.9E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS12660 cf55acf6312ddb6a98c9f5a7493ae6d2 164 SUPERFAMILY SSF54862 17 124 3.56E-19 T 06-07-2017 LK06_RS12660 cf55acf6312ddb6a98c9f5a7493ae6d2 164 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 81 92 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS12660 cf55acf6312ddb6a98c9f5a7493ae6d2 164 Pfam PF00037 4Fe-4S binding domain 76 96 6.2E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LK06_RS12660 cf55acf6312ddb6a98c9f5a7493ae6d2 164 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 32 43 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LK06_RS12660 cf55acf6312ddb6a98c9f5a7493ae6d2 164 Gene3D G3DSA:3.30.70.20 28 114 3.4E-16 T 06-07-2017 LK06_RS21370 fdaab2a863ccb24da2899bc6cc005d9b 184 Gene3D G3DSA:3.40.30.10 2 177 5.0E-61 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS21370 fdaab2a863ccb24da2899bc6cc005d9b 184 Pfam PF00578 AhpC/TSA family 4 136 6.7E-34 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LK06_RS21370 fdaab2a863ccb24da2899bc6cc005d9b 184 PIRSF PIRSF000239 1 184 1.5E-51 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LK06_RS21370 fdaab2a863ccb24da2899bc6cc005d9b 184 SUPERFAMILY SSF52833 2 177 5.98E-54 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS20755 3c949983fbf73897b5409e7589c6632d 186 Pfam PF04892 VanZ like family 24 143 1.5E-13 T 06-07-2017 IPR006976 VanZ-like LK06_RS17365 56f21653b3b0662d187ef74252fea6a5 173 Gene3D G3DSA:3.40.630.30 29 149 9.0E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS17365 56f21653b3b0662d187ef74252fea6a5 173 SUPERFAMILY SSF55729 24 151 1.74E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS17365 56f21653b3b0662d187ef74252fea6a5 173 Pfam PF00583 Acetyltransferase (GNAT) family 80 141 5.9E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS12310 82694a6c3f69a040511af8b4b0671932 218 Gene3D G3DSA:3.40.1370.10 58 203 3.4E-51 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 LK06_RS12310 82694a6c3f69a040511af8b4b0671932 218 SUPERFAMILY SSF52166 1 204 3.27E-74 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 LK06_RS12310 82694a6c3f69a040511af8b4b0671932 218 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 208 33.173 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12310 82694a6c3f69a040511af8b4b0671932 218 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 203 3.4E-70 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12310 82694a6c3f69a040511af8b4b0671932 218 Pfam PF00573 Ribosomal protein L4/L1 family 17 203 1.1E-64 T 06-07-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 LK06_RS05730 98b0bf28a95e6e5afdf325ec8af44c76 600 Pfam PF00723 Glycosyl hydrolases family 15 220 589 1.5E-72 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 LK06_RS05730 98b0bf28a95e6e5afdf325ec8af44c76 600 SUPERFAMILY SSF48208 193 593 6.05E-111 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS05730 98b0bf28a95e6e5afdf325ec8af44c76 600 Gene3D G3DSA:1.50.10.10 216 593 3.1E-83 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 LK06_RS14010 db276ef83711b3f510d4c99e6967c89f 801 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 30 744 1.5E-201 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 LK06_RS14010 db276ef83711b3f510d4c99e6967c89f 801 PIRSF PIRSF001265 21 753 2.4E-261 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 LK06_RS14010 db276ef83711b3f510d4c99e6967c89f 801 Pfam PF03030 Inorganic H+ pyrophosphatase 38 739 2.6E-237 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 LK06_RS14010 db276ef83711b3f510d4c99e6967c89f 801 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 26 744 24.353 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 LK06_RS06300 38ca0bab73e3bd5c1e9e43bcc449a137 314 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 279 313 0.0012 T 06-07-2017 IPR019931 LPXTG cell wall anchor domain LK06_RS06355 f6c73b90652027ac6914cf17f0d9378b 157 Gene3D G3DSA:3.40.630.30 1 136 6.1E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS06355 f6c73b90652027ac6914cf17f0d9378b 157 Pfam PF00583 Acetyltransferase (GNAT) family 54 133 1.7E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS06355 f6c73b90652027ac6914cf17f0d9378b 157 SUPERFAMILY SSF55729 2 137 4.46E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS01970 83aa475977645be06cc3b4b6e9f61ff0 455 SUPERFAMILY SSF51445 192 428 1.66E-37 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS01970 83aa475977645be06cc3b4b6e9f61ff0 455 Gene3D G3DSA:3.20.20.80 176 440 1.3E-41 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS01970 83aa475977645be06cc3b4b6e9f61ff0 455 Pfam PF02156 Glycosyl hydrolase family 26 276 354 1.7E-9 T 06-07-2017 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 LK06_RS30060 686e16d09d8cf0829549127426dc13d2 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 9.0E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30060 686e16d09d8cf0829549127426dc13d2 201 SUPERFAMILY SSF46689 7 84 1.8E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS30060 686e16d09d8cf0829549127426dc13d2 201 SUPERFAMILY SSF48498 78 187 1.81E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS30060 686e16d09d8cf0829549127426dc13d2 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30060 686e16d09d8cf0829549127426dc13d2 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS30060 686e16d09d8cf0829549127426dc13d2 201 Gene3D G3DSA:1.10.357.10 6 191 3.4E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS15865 49e6ffe483fb40513a49a7cb8ebfd1ff 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 2.8E-20 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS15865 49e6ffe483fb40513a49a7cb8ebfd1ff 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 06-07-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS15865 49e6ffe483fb40513a49a7cb8ebfd1ff 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.729 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS15865 49e6ffe483fb40513a49a7cb8ebfd1ff 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 3.0E-13 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS15865 49e6ffe483fb40513a49a7cb8ebfd1ff 45 Pfam PF00468 Ribosomal protein L34 3 45 2.0E-20 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS31510 e42be8ec0882e65925cd83a55ac209bd 82 Pfam PF00550 Phosphopantetheine attachment site 3 69 9.1E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31510 e42be8ec0882e65925cd83a55ac209bd 82 Gene3D G3DSA:1.10.1200.10 3 73 2.6E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31510 e42be8ec0882e65925cd83a55ac209bd 82 SUPERFAMILY SSF47336 2 73 1.83E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS15925 9b737e057f9eeb519a9a1a8da0b585ca 241 Pfam PF08281 Sigma-70, region 4 130 182 8.1E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15925 9b737e057f9eeb519a9a1a8da0b585ca 241 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 183 3.0E-27 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15925 9b737e057f9eeb519a9a1a8da0b585ca 241 SUPERFAMILY SSF88946 8 115 1.81E-28 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15925 9b737e057f9eeb519a9a1a8da0b585ca 241 Gene3D G3DSA:1.10.10.10 124 186 1.6E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15925 9b737e057f9eeb519a9a1a8da0b585ca 241 SUPERFAMILY SSF88659 124 185 2.18E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15925 9b737e057f9eeb519a9a1a8da0b585ca 241 Pfam PF04542 Sigma-70 region 2 31 97 3.1E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS15925 9b737e057f9eeb519a9a1a8da0b585ca 241 Gene3D G3DSA:1.10.1740.10 10 117 2.9E-30 T 06-07-2017 LK06_RS18465 f53e33496ce59c238bdd23ebd3675d3b 286 Gene3D G3DSA:3.40.190.10 83 185 4.6E-15 T 06-07-2017 LK06_RS18465 f53e33496ce59c238bdd23ebd3675d3b 286 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 8 276 39.843 T 06-07-2017 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 LK06_RS18465 f53e33496ce59c238bdd23ebd3675d3b 286 Pfam PF02621 Menaquinone biosynthesis 9 270 1.4E-87 T 06-07-2017 IPR003773 Menaquinone biosynthesis enzyme LK06_RS18465 f53e33496ce59c238bdd23ebd3675d3b 286 SUPERFAMILY SSF53850 9 275 3.36E-80 T 06-07-2017 LK06_RS28820 ad2364bd3b4507e0522fbcab0d97f274 144 SUPERFAMILY SSF103196 9 133 2.88E-24 T 06-07-2017 LK06_RS28820 ad2364bd3b4507e0522fbcab0d97f274 144 SMART SM00960 14 104 3.9E-23 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS28820 ad2364bd3b4507e0522fbcab0d97f274 144 Pfam PF03259 Roadblock/LC7 domain 13 104 7.9E-24 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS28820 ad2364bd3b4507e0522fbcab0d97f274 144 Gene3D G3DSA:3.30.450.30 8 128 3.0E-19 T 06-07-2017 LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 250 1.0E-59 T 06-07-2017 LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 SUPERFAMILY SSF51735 10 252 1.51E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 Gene3D G3DSA:3.40.50.720 6 251 2.1E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS25015 3ec273a94c84fedda33ba16aa7578528 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS28550 3159af04acd502ce503a8be05d5a6bb5 312 SUPERFAMILY SSF51735 2 310 1.35E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28550 3159af04acd502ce503a8be05d5a6bb5 312 PIRSF PIRSF001439 1 311 7.8E-45 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LK06_RS28550 3159af04acd502ce503a8be05d5a6bb5 312 Gene3D G3DSA:3.40.50.720 133 283 2.2E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS28550 3159af04acd502ce503a8be05d5a6bb5 312 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 2 301 9.6E-34 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LK06_RS28550 3159af04acd502ce503a8be05d5a6bb5 312 Gene3D G3DSA:3.30.1780.10 2 132 9.8E-25 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 LK06_RS17540 b468bbe4f17aaf1a7774fda9690a296d 130 Pfam PF00293 NUDIX domain 6 128 1.4E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS17540 b468bbe4f17aaf1a7774fda9690a296d 130 Gene3D G3DSA:3.90.79.10 6 130 3.5E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS17540 b468bbe4f17aaf1a7774fda9690a296d 130 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS17540 b468bbe4f17aaf1a7774fda9690a296d 130 SUPERFAMILY SSF55811 6 129 5.69E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS13240 bb189224728380d94fb505ae12f4f8f9 104 SUPERFAMILY SSF46785 7 93 7.55E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13240 bb189224728380d94fb505ae12f4f8f9 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 3.2E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13240 bb189224728380d94fb505ae12f4f8f9 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 3.2E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13240 bb189224728380d94fb505ae12f4f8f9 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 3.2E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13240 bb189224728380d94fb505ae12f4f8f9 104 Gene3D G3DSA:1.10.10.10 8 89 7.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13240 bb189224728380d94fb505ae12f4f8f9 104 SMART SM00418 8 86 2.0E-28 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS13240 bb189224728380d94fb505ae12f4f8f9 104 Pfam PF01022 Bacterial regulatory protein, arsR family 15 61 1.1E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS04400 da4d6c53a6adae96d8e14005ad0741b5 86 Pfam PF13560 Helix-turn-helix domain 13 71 2.0E-15 T 06-07-2017 LK06_RS04400 da4d6c53a6adae96d8e14005ad0741b5 86 SMART SM00530 16 71 1.0E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS04400 da4d6c53a6adae96d8e14005ad0741b5 86 Gene3D G3DSA:1.10.260.40 3 76 7.9E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS04400 da4d6c53a6adae96d8e14005ad0741b5 86 SUPERFAMILY SSF47413 8 74 2.56E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS23450 c32b661da5e604926412ba809a0e6f01 268 Pfam PF01987 Mitochondrial biogenesis AIM24 31 216 2.3E-9 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS23450 c32b661da5e604926412ba809a0e6f01 268 Gene3D G3DSA:3.60.160.10 23 218 1.1E-20 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS23450 c32b661da5e604926412ba809a0e6f01 268 SUPERFAMILY SSF51219 24 217 3.92E-28 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain LK06_RS13160 4326020b41e081972876a6c5f9931b15 409 SUPERFAMILY SSF53756 76 374 4.44E-14 T 06-07-2017 LK06_RS13160 4326020b41e081972876a6c5f9931b15 409 Gene3D G3DSA:3.40.50.2000 222 371 3.7E-4 T 06-07-2017 LK06_RS13160 4326020b41e081972876a6c5f9931b15 409 Pfam PF13692 Glycosyl transferases group 1 233 371 1.6E-6 T 06-07-2017 LK06_RS22750 c66b66c14fea525d9ee09c632b2fa5b3 369 Gene3D G3DSA:1.10.620.20 36 253 1.2E-19 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 LK06_RS22750 c66b66c14fea525d9ee09c632b2fa5b3 369 SUPERFAMILY SSF47240 89 318 5.98E-68 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS22750 c66b66c14fea525d9ee09c632b2fa5b3 369 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 37 305 2.3E-13 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF LK06_RS23315 d3dd7099d065833647dff223200c324b 148 Pfam PF10739 Protein of unknown function (DUF2550) 12 142 1.1E-45 T 06-07-2017 IPR019675 Protein of unknown function DUF2550 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 06-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 4.3E-30 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 73 3.0E-24 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 20.706 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 Pfam PF01084 Ribosomal protein S18 20 71 5.4E-24 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 SUPERFAMILY SSF46911 5 75 3.01E-28 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 8.4E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 8.4E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 8.4E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 8.4E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS16000 34402d4140841ec86d8e93f5f87ed881 78 Gene3D G3DSA:4.10.640.10 11 75 3.0E-32 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS01530 eb1ccd29ead641e2e84cae01e9710979 450 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 40 344 2.9E-83 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LK06_RS01530 eb1ccd29ead641e2e84cae01e9710979 450 PIRSF PIRSF017901 2 434 1.6E-116 T 06-07-2017 LK06_RS01530 eb1ccd29ead641e2e84cae01e9710979 450 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 27 417 5.7E-146 T 06-07-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LK06_RS01530 eb1ccd29ead641e2e84cae01e9710979 450 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 15 415 32.308 T 06-07-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LK06_RS01530 eb1ccd29ead641e2e84cae01e9710979 450 SUPERFAMILY SSF55931 32 257 1.18E-36 T 06-07-2017 LK06_RS01530 eb1ccd29ead641e2e84cae01e9710979 450 SUPERFAMILY SSF55931 293 424 1.18E-36 T 06-07-2017 LK06_RS12010 675fecab7f53197422234f64f1705e0f 392 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 10 367 2.8E-119 T 06-07-2017 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 LK06_RS12010 675fecab7f53197422234f64f1705e0f 392 Gene3D G3DSA:3.20.20.140 4 387 1.5E-150 T 06-07-2017 LK06_RS12010 675fecab7f53197422234f64f1705e0f 392 SUPERFAMILY SSF51556 4 250 1.11E-103 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS12010 675fecab7f53197422234f64f1705e0f 392 SUPERFAMILY SSF51556 290 379 1.11E-103 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS13785 496767ea24b69e1d32448e1bb69b9e9a 203 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 39 169 1.1E-37 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LK06_RS13785 496767ea24b69e1d32448e1bb69b9e9a 203 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 124 135 - T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LK06_RS13785 496767ea24b69e1d32448e1bb69b9e9a 203 Gene3D G3DSA:3.30.70.560 38 190 4.3E-56 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LK06_RS13785 496767ea24b69e1d32448e1bb69b9e9a 203 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 38 169 8.1E-44 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LK06_RS13785 496767ea24b69e1d32448e1bb69b9e9a 203 SUPERFAMILY SSF55083 37 188 6.15E-50 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LK06_RS09480 752cc3f036170f807a57b7be712a7738 130 SUPERFAMILY SSF54593 3 126 2.55E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS09480 752cc3f036170f807a57b7be712a7738 130 Gene3D G3DSA:3.10.180.10 3 126 6.6E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS09480 752cc3f036170f807a57b7be712a7738 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 122 6.7E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS23840 d9fe99a4a476f5398f5ebe3f7d07f437 224 SUPERFAMILY SSF55846 73 217 4.06E-41 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS23840 d9fe99a4a476f5398f5ebe3f7d07f437 224 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 84 205 6.0E-23 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS23840 d9fe99a4a476f5398f5ebe3f7d07f437 224 Gene3D G3DSA:3.40.80.10 65 219 2.4E-42 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS23840 d9fe99a4a476f5398f5ebe3f7d07f437 224 SMART SM00644 75 204 2.9E-42 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 LK06_RS05895 e74aec6e9dddbaea4012692c01f1f21d 143 SUPERFAMILY SSF141322 79 142 3.27E-6 T 06-07-2017 LK06_RS05895 e74aec6e9dddbaea4012692c01f1f21d 143 Gene3D G3DSA:2.40.50.140 84 142 4.3E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS05895 e74aec6e9dddbaea4012692c01f1f21d 143 Pfam PF01957 NfeD-like C-terminal, partner-binding 9 142 7.2E-18 T 06-07-2017 IPR002810 NfeD-like, C-terminal domain LK06_RS09085 e993f272ddb7f1d1c76ce98898383e57 170 Pfam PF12728 Helix-turn-helix domain 119 162 5.3E-8 T 06-07-2017 LK06_RS09085 e993f272ddb7f1d1c76ce98898383e57 170 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 119 162 2.8E-9 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 LK06_RS08725 610d5793a0f4ffdbf56d0e6ad8cefa1e 367 Pfam PF12671 Putative amidase domain 211 364 1.0E-33 T 06-07-2017 IPR024301 Putative amidase domain LK06_RS18040 b05b653af3816d0f1234faac99f0d6d0 176 Gene3D G3DSA:3.40.630.30 24 174 1.3E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS18040 b05b653af3816d0f1234faac99f0d6d0 176 Pfam PF13673 Acetyltransferase (GNAT) domain 88 163 1.5E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS18040 b05b653af3816d0f1234faac99f0d6d0 176 SUPERFAMILY SSF55729 8 172 2.74E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS17735 6518ac8d9df6fcf31b5d76410bda5c20 362 SMART SM00331 129 354 1.4E-27 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS17735 6518ac8d9df6fcf31b5d76410bda5c20 362 Pfam PF13411 MerR HTH family regulatory protein 5 71 1.9E-12 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS17735 6518ac8d9df6fcf31b5d76410bda5c20 362 SMART SM00422 4 74 5.9E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS17735 6518ac8d9df6fcf31b5d76410bda5c20 362 Gene3D G3DSA:1.10.1660.10 4 95 6.8E-19 T 06-07-2017 LK06_RS17735 6518ac8d9df6fcf31b5d76410bda5c20 362 Gene3D G3DSA:3.60.40.10 122 354 9.6E-65 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS17735 6518ac8d9df6fcf31b5d76410bda5c20 362 SMART SM00332 114 352 1.7E-20 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS17735 6518ac8d9df6fcf31b5d76410bda5c20 362 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS17735 6518ac8d9df6fcf31b5d76410bda5c20 362 SUPERFAMILY SSF81606 123 354 1.57E-55 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS17735 6518ac8d9df6fcf31b5d76410bda5c20 362 Pfam PF13672 Protein phosphatase 2C 137 312 3.2E-10 T 06-07-2017 LK06_RS17735 6518ac8d9df6fcf31b5d76410bda5c20 362 SUPERFAMILY SSF46955 4 104 1.83E-19 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS00295 8b876dad29290b90b88b1502da432638 147 Pfam PF00582 Universal stress protein family 9 143 2.2E-29 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS00295 8b876dad29290b90b88b1502da432638 147 PRINTS PR01438 Universal stress protein signature 7 25 3.1E-18 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00295 8b876dad29290b90b88b1502da432638 147 PRINTS PR01438 Universal stress protein signature 121 143 3.1E-18 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00295 8b876dad29290b90b88b1502da432638 147 PRINTS PR01438 Universal stress protein signature 103 115 3.1E-18 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00295 8b876dad29290b90b88b1502da432638 147 Gene3D G3DSA:3.40.50.620 9 145 5.0E-37 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS00295 8b876dad29290b90b88b1502da432638 147 SUPERFAMILY SSF52402 9 144 2.16E-34 T 06-07-2017 LK06_RS00470 e34c4f322b87667f0ff9c17a1f0abf3d 264 SUPERFAMILY SSF53335 15 257 1.74E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS00470 e34c4f322b87667f0ff9c17a1f0abf3d 264 Pfam PF04672 S-adenosyl methyltransferase 7 262 4.5E-106 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS00470 e34c4f322b87667f0ff9c17a1f0abf3d 264 Gene3D G3DSA:3.40.50.150 5 262 8.2E-109 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS00470 e34c4f322b87667f0ff9c17a1f0abf3d 264 PIRSF PIRSF017393 1 263 6.7E-108 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type LK06_RS04420 eb4262ea7cadcab6a415024e3be28b0a 156 Pfam PF13581 Histidine kinase-like ATPase domain 31 149 1.9E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04420 eb4262ea7cadcab6a415024e3be28b0a 156 SUPERFAMILY SSF55874 39 153 6.67E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS27180 18d6cabfe43acaaab53e0bf95e789d2d 100 SUPERFAMILY SSF48600 5 94 1.48E-17 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS27180 18d6cabfe43acaaab53e0bf95e789d2d 100 Gene3D G3DSA:1.20.59.10 7 93 7.5E-14 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS27180 18d6cabfe43acaaab53e0bf95e789d2d 100 TIGRFAM TIGR01803 CM-like: chorismate mutase related enzymes 11 92 6.0E-25 T 06-07-2017 IPR008241 Salicylate biosynthesis protein PchB GO:0004106|GO:0009697|GO:0016835 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6406|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS27180 18d6cabfe43acaaab53e0bf95e789d2d 100 Pfam PF01817 Chorismate mutase type II 15 92 2.5E-12 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS27180 18d6cabfe43acaaab53e0bf95e789d2d 100 SMART SM00830 15 95 8.9E-12 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LK06_RS27585 5b4123d21e3589ff9f54eb536d5d60ab 263 Pfam PF00005 ABC transporter 26 180 4.8E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS27585 5b4123d21e3589ff9f54eb536d5d60ab 263 Gene3D G3DSA:3.40.50.300 3 245 2.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27585 5b4123d21e3589ff9f54eb536d5d60ab 263 SMART SM00382 35 228 5.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS27585 5b4123d21e3589ff9f54eb536d5d60ab 263 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS27585 5b4123d21e3589ff9f54eb536d5d60ab 263 SUPERFAMILY SSF52540 10 238 1.95E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25475 3341ab6b05bd9b2accca6b2df128d062 194 SUPERFAMILY SSF54637 21 159 1.79E-34 T 06-07-2017 IPR029069 HotDog domain LK06_RS25475 3341ab6b05bd9b2accca6b2df128d062 194 Pfam PF03061 Thioesterase superfamily 75 143 1.1E-9 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 LK06_RS25475 3341ab6b05bd9b2accca6b2df128d062 194 Gene3D G3DSA:3.10.129.10 21 167 1.3E-45 T 06-07-2017 IPR029069 HotDog domain LK06_RS21985 7e022beb41051f19a05f3e1f15e4b503 359 SUPERFAMILY SSF55031 170 270 1.38E-19 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS21985 7e022beb41051f19a05f3e1f15e4b503 359 SUPERFAMILY SSF53187 280 357 4.1E-44 T 06-07-2017 LK06_RS21985 7e022beb41051f19a05f3e1f15e4b503 359 SUPERFAMILY SSF53187 14 182 4.1E-44 T 06-07-2017 LK06_RS21985 7e022beb41051f19a05f3e1f15e4b503 359 Pfam PF07687 Peptidase dimerisation domain 170 268 5.7E-15 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS21985 7e022beb41051f19a05f3e1f15e4b503 359 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 11 358 2.3E-158 T 06-07-2017 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 LK06_RS21985 7e022beb41051f19a05f3e1f15e4b503 359 Pfam PF01546 Peptidase family M20/M25/M40 69 354 9.6E-23 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 LK06_RS21985 7e022beb41051f19a05f3e1f15e4b503 359 Gene3D G3DSA:3.30.70.360 171 271 5.7E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain LK06_RS21985 7e022beb41051f19a05f3e1f15e4b503 359 Gene3D G3DSA:3.40.630.10 12 170 6.4E-46 T 06-07-2017 LK06_RS21985 7e022beb41051f19a05f3e1f15e4b503 359 Gene3D G3DSA:3.40.630.10 280 355 6.4E-46 T 06-07-2017 LK06_RS15010 544bdbe4fa9383039e7c3e0c6bc4e97f 144 Gene3D G3DSA:2.30.110.10 14 142 4.8E-32 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS15010 544bdbe4fa9383039e7c3e0c6bc4e97f 144 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 20 122 1.6E-22 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related LK06_RS15010 544bdbe4fa9383039e7c3e0c6bc4e97f 144 SUPERFAMILY SSF50475 16 141 4.91E-17 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS21905 d82a411c33746ca324b86bdfd1e58ce1 365 Pfam PF00005 ABC transporter 37 188 2.5E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS21905 d82a411c33746ca324b86bdfd1e58ce1 365 SUPERFAMILY SSF52540 9 260 8.87E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21905 d82a411c33746ca324b86bdfd1e58ce1 365 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 314 2.2E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21905 d82a411c33746ca324b86bdfd1e58ce1 365 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS21905 d82a411c33746ca324b86bdfd1e58ce1 365 Gene3D G3DSA:3.40.50.300 7 262 3.5E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21905 d82a411c33746ca324b86bdfd1e58ce1 365 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 307 1.1E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LK06_RS21905 d82a411c33746ca324b86bdfd1e58ce1 365 SMART SM00382 45 238 2.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS14980 bc5c0b76664f9dd6fa0983061b924ae8 227 Pfam PF01066 CDP-alcohol phosphatidyltransferase 80 134 3.4E-8 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS14980 bc5c0b76664f9dd6fa0983061b924ae8 227 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 112 134 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS28180 2b5b8a58668f01287bfc8cb77836aa28 101 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 94 9.4E-24 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 LK06_RS28180 2b5b8a58668f01287bfc8cb77836aa28 101 SUPERFAMILY SSF55248 3 95 2.88E-24 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 LK06_RS28180 2b5b8a58668f01287bfc8cb77836aa28 101 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 3 95 20.552 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 LK06_RS28180 2b5b8a58668f01287bfc8cb77836aa28 101 Gene3D G3DSA:3.30.1360.20 2 95 1.1E-23 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 LK06_RS13085 8ebfda6c3092b5e53f7115e05a85b337 470 SUPERFAMILY SSF52777 241 464 2.0E-16 T 06-07-2017 LK06_RS13085 8ebfda6c3092b5e53f7115e05a85b337 470 Pfam PF00668 Condensation domain 67 339 2.1E-8 T 06-07-2017 IPR001242 Condensation domain LK06_RS13085 8ebfda6c3092b5e53f7115e05a85b337 470 SUPERFAMILY SSF52777 34 213 4.89E-19 T 06-07-2017 LK06_RS29255 a5c48426be3cb60e6b01624caaebbd4a 499 Gene3D G3DSA:1.20.1250.20 19 199 2.2E-26 T 06-07-2017 LK06_RS29255 a5c48426be3cb60e6b01624caaebbd4a 499 Gene3D G3DSA:1.20.1250.20 280 475 3.2E-16 T 06-07-2017 LK06_RS29255 a5c48426be3cb60e6b01624caaebbd4a 499 Pfam PF07690 Major Facilitator Superfamily 23 420 4.3E-34 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS29255 a5c48426be3cb60e6b01624caaebbd4a 499 SUPERFAMILY SSF103473 254 476 2.22E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS29255 a5c48426be3cb60e6b01624caaebbd4a 499 SUPERFAMILY SSF103473 17 208 2.22E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS17165 99fc28b5e028aff078acf93b73a34bdf 173 PRINTS PR00502 NUDIX hydrolase family signature 68 83 8.5E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS17165 99fc28b5e028aff078acf93b73a34bdf 173 PRINTS PR00502 NUDIX hydrolase family signature 54 68 8.5E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS17165 99fc28b5e028aff078acf93b73a34bdf 173 SUPERFAMILY SSF55811 27 159 2.44E-23 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS17165 99fc28b5e028aff078acf93b73a34bdf 173 ProSitePatterns PS00893 Nudix box signature. 59 80 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS17165 99fc28b5e028aff078acf93b73a34bdf 173 Gene3D G3DSA:3.90.79.10 27 162 2.0E-22 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS17165 99fc28b5e028aff078acf93b73a34bdf 173 Pfam PF00293 NUDIX domain 28 153 1.6E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS22285 de6652f1a41c9578a4dc4a0713624cf4 489 Pfam PF10103 Zinicin-like metallopeptidase 89 441 3.1E-127 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 LK06_RS22285 de6652f1a41c9578a4dc4a0713624cf4 489 SUPERFAMILY SSF55486 88 443 7.32E-117 T 06-07-2017 LK06_RS22285 de6652f1a41c9578a4dc4a0713624cf4 489 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 89 443 1.6E-122 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 LK06_RS06390 a6e20e96ff188c3d45997d01e9ded052 266 Gene3D G3DSA:1.20.1250.20 12 168 1.1E-11 T 06-07-2017 LK06_RS06390 a6e20e96ff188c3d45997d01e9ded052 266 SUPERFAMILY SSF103473 13 168 3.66E-12 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS12370 f2aa6922ce7de332ea97e21a7513e4a1 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.6E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS12370 f2aa6922ce7de332ea97e21a7513e4a1 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.6E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS12370 f2aa6922ce7de332ea97e21a7513e4a1 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.6E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS12370 f2aa6922ce7de332ea97e21a7513e4a1 321 Gene3D G3DSA:3.40.190.10 97 181 1.0E-6 T 06-07-2017 LK06_RS12370 f2aa6922ce7de332ea97e21a7513e4a1 321 SUPERFAMILY SSF53850 95 292 4.52E-18 T 06-07-2017 LK06_RS12370 f2aa6922ce7de332ea97e21a7513e4a1 321 Pfam PF03466 LysR substrate binding domain 93 294 1.6E-19 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS12370 f2aa6922ce7de332ea97e21a7513e4a1 321 SUPERFAMILY SSF46785 3 114 2.94E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12370 f2aa6922ce7de332ea97e21a7513e4a1 321 Gene3D G3DSA:1.10.10.10 2 83 1.1E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12370 f2aa6922ce7de332ea97e21a7513e4a1 321 Gene3D G3DSA:3.40.190.10 182 267 1.4E-15 T 06-07-2017 LK06_RS12370 f2aa6922ce7de332ea97e21a7513e4a1 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.2E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS24885 e342b4cd30d38d2cce4f843bef1435c6 459 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 66 89 - T 06-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 LK06_RS24885 e342b4cd30d38d2cce4f843bef1435c6 459 SUPERFAMILY SSF63411 264 450 9.41E-46 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LK06_RS24885 e342b4cd30d38d2cce4f843bef1435c6 459 Pfam PF05193 Peptidase M16 inactive domain 199 380 5.6E-43 T 06-07-2017 IPR007863 Peptidase M16, C-terminal LK06_RS24885 e342b4cd30d38d2cce4f843bef1435c6 459 Gene3D G3DSA:3.30.830.10 35 240 3.6E-56 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 LK06_RS24885 e342b4cd30d38d2cce4f843bef1435c6 459 Pfam PF00675 Insulinase (Peptidase family M16) 45 192 6.4E-36 T 06-07-2017 IPR011765 Peptidase M16, N-terminal LK06_RS24885 e342b4cd30d38d2cce4f843bef1435c6 459 Gene3D G3DSA:3.30.830.10 269 448 2.4E-54 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 LK06_RS24885 e342b4cd30d38d2cce4f843bef1435c6 459 SUPERFAMILY SSF63411 34 238 3.48E-58 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LK06_RS22665 2f835c51ef81c96d3f27531695a674a3 246 SMART SM00448 20 130 7.4E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS22665 2f835c51ef81c96d3f27531695a674a3 246 Gene3D G3DSA:3.40.50.2300 9 138 1.0E-39 T 06-07-2017 LK06_RS22665 2f835c51ef81c96d3f27531695a674a3 246 Pfam PF00072 Response regulator receiver domain 22 130 7.2E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS22665 2f835c51ef81c96d3f27531695a674a3 246 SMART SM00862 170 241 4.2E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS22665 2f835c51ef81c96d3f27531695a674a3 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 171 241 1.2E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS22665 2f835c51ef81c96d3f27531695a674a3 246 SUPERFAMILY SSF46894 147 242 3.12E-27 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS22665 2f835c51ef81c96d3f27531695a674a3 246 SUPERFAMILY SSF52172 17 139 1.85E-41 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS22665 2f835c51ef81c96d3f27531695a674a3 246 Gene3D G3DSA:1.10.10.10 148 243 1.1E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14500 855c1007d10bca69af36bea01f541475 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 109.162 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 LK06_RS14500 855c1007d10bca69af36bea01f541475 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 2.0E-85 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 LK06_RS14500 855c1007d10bca69af36bea01f541475 199 SUPERFAMILY SSF111304 3 197 4.45E-75 T 06-07-2017 IPR023627 Recombination protein RecR LK06_RS14500 855c1007d10bca69af36bea01f541475 199 Pfam PF00633 Helix-hairpin-helix motif 2 27 3.5E-6 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 LK06_RS14500 855c1007d10bca69af36bea01f541475 199 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 06-07-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 LK06_RS14500 855c1007d10bca69af36bea01f541475 199 Pfam PF13662 Toprim domain 80 170 3.6E-26 T 06-07-2017 IPR006171 Toprim domain LK06_RS14500 855c1007d10bca69af36bea01f541475 199 Gene3D G3DSA:3.40.50.140 115 169 4.4E-6 T 06-07-2017 IPR006171 Toprim domain LK06_RS14500 855c1007d10bca69af36bea01f541475 199 Pfam PF02132 RecR protein 38 77 1.6E-16 T 06-07-2017 IPR023628 Recombination protein RecR, C4-type zinc finger LK06_RS14500 855c1007d10bca69af36bea01f541475 199 SMART SM00493 79 164 3.2E-17 T 06-07-2017 IPR006171 Toprim domain LK06_RS31650 63664d8ac5b5ba86db0a6e3b1d00c2f9 67 SUPERFAMILY SSF51735 6 61 5.87E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31650 63664d8ac5b5ba86db0a6e3b1d00c2f9 67 Gene3D G3DSA:3.40.50.720 9 63 4.9E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31650 63664d8ac5b5ba86db0a6e3b1d00c2f9 67 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 10 62 2.0E-10 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LK06_RS10185 8a56fc61d80bbd99e5cf6457cacca3cb 225 PIRSF PIRSF012637 1 223 8.8E-70 T 06-07-2017 IPR016601 Uncharacterised conserved protein UCP012637 LK06_RS07770 2a0b5a67dc80ab5b7a92eedf6dabc6ba 261 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 261 39.214 T 06-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS07770 2a0b5a67dc80ab5b7a92eedf6dabc6ba 261 Pfam PF02654 Cobalamin-5-phosphate synthase 13 254 4.7E-43 T 06-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 LK06_RS15805 c992b6b5572d62043fbecafb4251e6d6 62 Pfam PF12728 Helix-turn-helix domain 8 57 2.9E-10 T 06-07-2017 LK06_RS32125 7c5dc59bfff376b41e1e3e89a39e5732 420 Pfam PF13535 ATP-grasp domain 191 288 8.2E-8 T 06-07-2017 LK06_RS32125 7c5dc59bfff376b41e1e3e89a39e5732 420 SUPERFAMILY SSF56059 113 295 5.3E-26 T 06-07-2017 LK06_RS32125 7c5dc59bfff376b41e1e3e89a39e5732 420 Gene3D G3DSA:3.30.470.20 112 290 2.2E-17 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS31430 e0f1fdbb289f8e9c02f71575c0032f88 232 Pfam PF00535 Glycosyl transferase family 2 11 129 4.7E-18 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS31430 e0f1fdbb289f8e9c02f71575c0032f88 232 SUPERFAMILY SSF53448 9 219 6.14E-35 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS31430 e0f1fdbb289f8e9c02f71575c0032f88 232 Gene3D G3DSA:3.90.550.10 10 188 3.3E-16 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS00650 9cbe119353bf322cb7a795aa3e43d0a7 911 Pfam PF13802 Galactose mutarotase-like 328 383 2.8E-7 T 06-07-2017 IPR025887 Glycoside hydrolase family 31, N-terminal domain LK06_RS00650 9cbe119353bf322cb7a795aa3e43d0a7 911 SUPERFAMILY SSF74650 206 409 1.44E-29 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 LK06_RS00650 9cbe119353bf322cb7a795aa3e43d0a7 911 Pfam PF17137 Domain of unknown function (DUF5110) 790 863 2.6E-15 T 06-07-2017 IPR033403 Domain of unknown function DUF5110 LK06_RS00650 9cbe119353bf322cb7a795aa3e43d0a7 911 SUPERFAMILY SSF51011 688 769 2.52E-18 T 06-07-2017 LK06_RS00650 9cbe119353bf322cb7a795aa3e43d0a7 911 Pfam PF01055 Glycosyl hydrolases family 31 546 773 2.9E-51 T 06-07-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 LK06_RS00650 9cbe119353bf322cb7a795aa3e43d0a7 911 SUPERFAMILY SSF51445 411 684 2.32E-25 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS29655 51b98f7cf93bc9eab44927298fe0e68c 137 Pfam PF03259 Roadblock/LC7 domain 8 96 9.6E-26 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS29655 51b98f7cf93bc9eab44927298fe0e68c 137 Gene3D G3DSA:3.30.450.30 3 122 9.7E-26 T 06-07-2017 LK06_RS29655 51b98f7cf93bc9eab44927298fe0e68c 137 SMART SM00960 8 98 3.4E-28 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS29655 51b98f7cf93bc9eab44927298fe0e68c 137 SUPERFAMILY SSF103196 4 127 3.84E-34 T 06-07-2017 LK06_RS08585 c999146ee7f8157499919b587f6d01e1 370 Pfam PF02361 Cobalt transport protein 49 230 2.8E-8 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component LK06_RS13275 0126cab6dd284fc9b3d004bb9ec1f7d3 246 Gene3D G3DSA:3.60.15.10 3 237 2.7E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS13275 0126cab6dd284fc9b3d004bb9ec1f7d3 246 Pfam PF12706 Beta-lactamase superfamily domain 19 216 2.4E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS13275 0126cab6dd284fc9b3d004bb9ec1f7d3 246 SUPERFAMILY SSF56281 2 240 6.0E-17 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS10100 e49871bbe7e7b4d0675d9cb9f8a9e519 178 Pfam PF14279 HNH endonuclease 83 125 1.6E-13 T 06-07-2017 IPR029471 HNH endonuclease 5 LK06_RS10100 e49871bbe7e7b4d0675d9cb9f8a9e519 178 SMART SM00507 70 119 8.6E-14 T 06-07-2017 IPR003615 HNH nuclease LK06_RS07355 8cd3bb3756a43516f3ca54efc67e878b 453 Pfam PF01882 Protein of unknown function DUF58 220 296 6.3E-20 T 06-07-2017 IPR002881 Domain of unknown function DUF58 LK06_RS08125 ec8391d19d84c6f296560f844d616b7e 275 Pfam PF14378 PAP2 superfamily 61 241 2.9E-46 T 06-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 LK06_RS24205 097293fe0677758604d7828c5c728c30 215 Gene3D G3DSA:3.90.550.10 5 168 3.4E-20 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS24205 097293fe0677758604d7828c5c728c30 215 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 3 211 21.832 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 LK06_RS24205 097293fe0677758604d7828c5c728c30 215 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 5 199 4.9E-50 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 LK06_RS24205 097293fe0677758604d7828c5c728c30 215 SUPERFAMILY SSF53448 4 200 2.13E-26 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS24205 097293fe0677758604d7828c5c728c30 215 Pfam PF01983 Guanylyl transferase CofC like 5 189 4.1E-10 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 Pfam PF00067 Cytochrome P450 25 436 3.4E-67 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 SUPERFAMILY SSF48264 16 455 1.57E-94 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 PRINTS PR00385 P450 superfamily signature 269 286 4.1E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 PRINTS PR00385 P450 superfamily signature 396 405 4.1E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 PRINTS PR00385 P450 superfamily signature 321 332 4.1E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 Gene3D G3DSA:1.10.630.10 16 455 1.7E-99 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 PRINTS PR00463 E-class P450 group I signature 278 304 6.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 PRINTS PR00463 E-class P450 group I signature 360 384 6.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 PRINTS PR00463 E-class P450 group I signature 395 405 6.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 PRINTS PR00463 E-class P450 group I signature 405 428 6.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 PRINTS PR00463 E-class P450 group I signature 46 65 6.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS22415 0b6455a1396f239fa1308a2272a60e54 456 PRINTS PR00463 E-class P450 group I signature 258 275 6.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS26760 80c5c2104a5ba4c57a07b61bbe9a3d59 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 208 1.1E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26760 80c5c2104a5ba4c57a07b61bbe9a3d59 222 SUPERFAMILY SSF161098 24 201 2.62E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26760 80c5c2104a5ba4c57a07b61bbe9a3d59 222 Gene3D G3DSA:1.10.3720.10 26 212 2.0E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS29170 81d6f30e7ee8cb125dc0abb197ae80a5 663 Gene3D G3DSA:3.50.50.60 8 204 2.0E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29170 81d6f30e7ee8cb125dc0abb197ae80a5 663 Gene3D G3DSA:3.50.50.60 574 613 2.0E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29170 81d6f30e7ee8cb125dc0abb197ae80a5 663 Pfam PF13454 FAD-NAD(P)-binding 9 197 1.2E-43 T 06-07-2017 LK06_RS29170 81d6f30e7ee8cb125dc0abb197ae80a5 663 SUPERFAMILY SSF51905 8 54 3.37E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS29170 81d6f30e7ee8cb125dc0abb197ae80a5 663 SUPERFAMILY SSF51905 91 218 3.37E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01725 21ebd93a727a565977b8b6de44b71922 428 Pfam PF01547 Bacterial extracellular solute-binding protein 52 337 6.5E-42 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 LK06_RS01725 21ebd93a727a565977b8b6de44b71922 428 Gene3D G3DSA:3.40.190.10 40 222 8.0E-37 T 06-07-2017 LK06_RS01725 21ebd93a727a565977b8b6de44b71922 428 SUPERFAMILY SSF53850 20 426 1.33E-68 T 06-07-2017 LK06_RS27105 a3fa57c153c23b3349546f9485979a8c 229 SMART SM00895 101 227 5.0E-14 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS27105 a3fa57c153c23b3349546f9485979a8c 229 SUPERFAMILY SSF46785 25 95 5.79E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27105 a3fa57c153c23b3349546f9485979a8c 229 SUPERFAMILY SSF48008 97 228 3.66E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS27105 a3fa57c153c23b3349546f9485979a8c 229 Pfam PF07729 FCD domain 101 226 6.1E-20 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS27105 a3fa57c153c23b3349546f9485979a8c 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 91 2.0E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS27105 a3fa57c153c23b3349546f9485979a8c 229 Gene3D G3DSA:1.20.120.530 97 228 4.4E-19 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS27105 a3fa57c153c23b3349546f9485979a8c 229 Gene3D G3DSA:1.10.10.10 18 91 4.8E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27105 a3fa57c153c23b3349546f9485979a8c 229 SMART SM00345 33 91 9.9E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS12640 43fb91c91ac26f78a26942144c6e1b94 542 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 59 538 7.9E-162 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12640 43fb91c91ac26f78a26942144c6e1b94 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 366 385 1.2E-39 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12640 43fb91c91ac26f78a26942144c6e1b94 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 200 224 1.2E-39 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12640 43fb91c91ac26f78a26942144c6e1b94 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 423 449 1.2E-39 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12640 43fb91c91ac26f78a26942144c6e1b94 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 272 296 1.2E-39 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12640 43fb91c91ac26f78a26942144c6e1b94 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 170 189 1.2E-39 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12640 43fb91c91ac26f78a26942144c6e1b94 542 Pfam PF00361 Proton-conducting membrane transporter 166 450 7.6E-60 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12480 a56e20bee378611f819b78154429ea4d 343 SUPERFAMILY SSF51556 8 340 3.85E-67 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS12480 a56e20bee378611f819b78154429ea4d 343 Gene3D G3DSA:3.20.20.140 7 340 2.1E-82 T 06-07-2017 LK06_RS12480 a56e20bee378611f819b78154429ea4d 343 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 281 287 - T 06-07-2017 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 LK06_RS12480 a56e20bee378611f819b78154429ea4d 343 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 10 336 2.3E-114 T 06-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 LK06_RS12480 a56e20bee378611f819b78154429ea4d 343 Pfam PF00962 Adenosine/AMP deaminase 10 335 9.8E-94 T 06-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 LK06_RS26170 e97a9698793304643d0c698eba910646 188 Gene3D G3DSA:1.10.357.10 7 177 2.4E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS26170 e97a9698793304643d0c698eba910646 188 SUPERFAMILY SSF48498 84 185 2.58E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS26170 e97a9698793304643d0c698eba910646 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 4.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS26170 e97a9698793304643d0c698eba910646 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 4.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS26170 e97a9698793304643d0c698eba910646 188 SUPERFAMILY SSF46689 4 88 2.98E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS26170 e97a9698793304643d0c698eba910646 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 3.5E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS01280 02b1fdf12a8e16abec786ea1a764acaf 270 Gene3D G3DSA:3.20.20.140 22 269 7.9E-58 T 06-07-2017 LK06_RS01280 02b1fdf12a8e16abec786ea1a764acaf 270 Pfam PF04909 Amidohydrolase 42 269 1.9E-39 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS01280 02b1fdf12a8e16abec786ea1a764acaf 270 SUPERFAMILY SSF51556 4 270 1.67E-57 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS08565 cec84bf503e8b28a41827aefda048666 340 SMART SM00849 24 250 1.3E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS08565 cec84bf503e8b28a41827aefda048666 340 SUPERFAMILY SSF56281 11 327 1.7E-55 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS08565 cec84bf503e8b28a41827aefda048666 340 Pfam PF00753 Metallo-beta-lactamase superfamily 23 250 1.7E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS08565 cec84bf503e8b28a41827aefda048666 340 Gene3D G3DSA:3.60.15.10 20 293 5.1E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS23325 0096c45a79a4d4d850becf7c59b6e159 231 Gene3D G3DSA:3.40.50.2300 6 128 2.8E-40 T 06-07-2017 LK06_RS23325 0096c45a79a4d4d850becf7c59b6e159 231 Pfam PF00072 Response regulator receiver domain 10 119 3.9E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS23325 0096c45a79a4d4d850becf7c59b6e159 231 SMART SM00862 152 227 2.0E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS23325 0096c45a79a4d4d850becf7c59b6e159 231 SUPERFAMILY SSF52172 6 185 1.96E-44 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS23325 0096c45a79a4d4d850becf7c59b6e159 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 1.7E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS23325 0096c45a79a4d4d850becf7c59b6e159 231 Gene3D G3DSA:1.10.10.10 129 229 9.9E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23325 0096c45a79a4d4d850becf7c59b6e159 231 SMART SM00448 8 119 2.5E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS11340 ed2d5b3f52425871329a362a9fb56750 263 SUPERFAMILY SSF54211 118 250 1.14E-18 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold LK06_RS11340 ed2d5b3f52425871329a362a9fb56750 263 Gene3D G3DSA:3.30.230.10 114 249 1.1E-22 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LK06_RS11340 ed2d5b3f52425871329a362a9fb56750 263 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 154 241 3.1E-7 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 LK06_RS19310 a97ee6946c82d694dbd0fbaba071795e 406 SUPERFAMILY SSF141523 248 376 1.24E-24 T 06-07-2017 LK06_RS19310 a97ee6946c82d694dbd0fbaba071795e 406 Gene3D G3DSA:2.40.440.10 248 377 6.3E-18 T 06-07-2017 LK06_RS19310 a97ee6946c82d694dbd0fbaba071795e 406 Pfam PF03734 L,D-transpeptidase catalytic domain 246 376 4.5E-16 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 LK06_RS31715 8ef7c129d5c8051fca8a79ab30e85790 408 Gene3D G3DSA:3.40.50.2000 231 380 2.0E-26 T 06-07-2017 LK06_RS31715 8ef7c129d5c8051fca8a79ab30e85790 408 SUPERFAMILY SSF53756 9 401 1.59E-67 T 06-07-2017 LK06_RS31715 8ef7c129d5c8051fca8a79ab30e85790 408 Gene3D G3DSA:3.40.50.2000 6 128 4.3E-17 T 06-07-2017 LK06_RS31715 8ef7c129d5c8051fca8a79ab30e85790 408 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 234 371 2.7E-15 T 06-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 LK06_RS27035 29f77759868c71eadca8decb6e2f1764 306 Pfam PF02574 Homocysteine S-methyltransferase 18 303 1.2E-68 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 LK06_RS27035 29f77759868c71eadca8decb6e2f1764 306 SUPERFAMILY SSF82282 10 305 2.35E-78 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 LK06_RS27035 29f77759868c71eadca8decb6e2f1764 306 Gene3D G3DSA:3.20.20.330 5 305 9.4E-88 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 LK06_RS00450 2dab0936b7e4b2dc1fb348c29b7ae060 199 Gene3D G3DSA:1.10.357.10 12 195 7.4E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS00450 2dab0936b7e4b2dc1fb348c29b7ae060 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 52 1.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS00450 2dab0936b7e4b2dc1fb348c29b7ae060 199 SUPERFAMILY SSF46689 14 68 7.98E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS19800 e59fec07e67b971c2f5b9f71defc1bb5 225 SUPERFAMILY SSF48498 102 212 4.67E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS19800 e59fec07e67b971c2f5b9f71defc1bb5 225 ProSitePatterns PS01081 TetR-type HTH domain signature. 47 77 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS19800 e59fec07e67b971c2f5b9f71defc1bb5 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 79 5.3E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS19800 e59fec07e67b971c2f5b9f71defc1bb5 225 Gene3D G3DSA:1.10.357.10 17 210 5.2E-47 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS19800 e59fec07e67b971c2f5b9f71defc1bb5 225 SUPERFAMILY SSF46689 21 99 1.03E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS19800 e59fec07e67b971c2f5b9f71defc1bb5 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 3.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS19800 e59fec07e67b971c2f5b9f71defc1bb5 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 3.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS13305 bb5a6ef842d54e93dcb4ebc644eff130 240 SUPERFAMILY SSF52172 3 124 5.27E-42 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS13305 bb5a6ef842d54e93dcb4ebc644eff130 240 SMART SM00862 162 237 3.9E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS13305 bb5a6ef842d54e93dcb4ebc644eff130 240 Gene3D G3DSA:3.40.50.2300 3 121 3.0E-40 T 06-07-2017 LK06_RS13305 bb5a6ef842d54e93dcb4ebc644eff130 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 237 3.4E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS13305 bb5a6ef842d54e93dcb4ebc644eff130 240 Pfam PF00072 Response regulator receiver domain 5 114 1.4E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS13305 bb5a6ef842d54e93dcb4ebc644eff130 240 SUPERFAMILY SSF46894 138 238 2.24E-27 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS13305 bb5a6ef842d54e93dcb4ebc644eff130 240 Gene3D G3DSA:1.10.10.10 141 239 1.2E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13305 bb5a6ef842d54e93dcb4ebc644eff130 240 SMART SM00448 3 114 1.4E-42 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25570 e4424c1fcbb21799f2aac40725df5806 1342 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 870 882 5.4E-13 T 06-07-2017 LK06_RS25570 e4424c1fcbb21799f2aac40725df5806 1342 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 568 584 5.4E-13 T 06-07-2017 LK06_RS25570 e4424c1fcbb21799f2aac40725df5806 1342 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 616 630 5.4E-13 T 06-07-2017 LK06_RS25570 e4424c1fcbb21799f2aac40725df5806 1342 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 910 934 5.4E-13 T 06-07-2017 LK06_RS25570 e4424c1fcbb21799f2aac40725df5806 1342 SUPERFAMILY SSF53335 559 712 2.63E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25570 e4424c1fcbb21799f2aac40725df5806 1342 SUPERFAMILY SSF53335 862 942 2.63E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25570 e4424c1fcbb21799f2aac40725df5806 1342 SUPERFAMILY SSF53335 283 440 2.63E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25570 e4424c1fcbb21799f2aac40725df5806 1342 Gene3D G3DSA:3.40.50.150 863 943 4.5E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25570 e4424c1fcbb21799f2aac40725df5806 1342 Gene3D G3DSA:3.40.50.150 570 710 4.5E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25570 e4424c1fcbb21799f2aac40725df5806 1342 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 873 879 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LK06_RS18470 b19ba73b0ed30a2a898cd9bc609acd55 243 Pfam PF01048 Phosphorylase superfamily 54 221 8.4E-13 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS18470 b19ba73b0ed30a2a898cd9bc609acd55 243 SUPERFAMILY SSF53167 6 214 2.75E-27 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS18470 b19ba73b0ed30a2a898cd9bc609acd55 243 Hamap MF_00991 Futalosine hydrolase [mqnB]. 20 232 24.538 T 06-07-2017 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 LK06_RS18470 b19ba73b0ed30a2a898cd9bc609acd55 243 Gene3D G3DSA:3.40.50.1580 5 240 3.7E-50 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LK06_RS18470 b19ba73b0ed30a2a898cd9bc609acd55 243 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 7 230 4.6E-63 T 06-07-2017 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 LK06_RS02175 a3f8b3892dbfdb07a557a1277a5ac64f 405 SUPERFAMILY SSF56645 16 242 2.62E-59 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS02175 a3f8b3892dbfdb07a557a1277a5ac64f 405 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 386 7.9E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS02175 a3f8b3892dbfdb07a557a1277a5ac64f 405 Gene3D G3DSA:2.40.110.10 110 218 2.7E-30 T 06-07-2017 LK06_RS02175 a3f8b3892dbfdb07a557a1277a5ac64f 405 SUPERFAMILY SSF47203 229 388 3.62E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS02175 a3f8b3892dbfdb07a557a1277a5ac64f 405 Gene3D G3DSA:1.20.140.10 219 396 1.1E-23 T 06-07-2017 LK06_RS02175 a3f8b3892dbfdb07a557a1277a5ac64f 405 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 111 206 1.1E-17 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS02175 a3f8b3892dbfdb07a557a1277a5ac64f 405 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 28 107 1.8E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS02175 a3f8b3892dbfdb07a557a1277a5ac64f 405 Gene3D G3DSA:1.10.540.10 12 108 1.2E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18420 1708b24e67e18dd61560d8463e24949b 228 SUPERFAMILY SSF47090 44 90 4.71E-5 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18420 1708b24e67e18dd61560d8463e24949b 228 Pfam PF03734 L,D-transpeptidase catalytic domain 111 219 8.0E-12 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 LK06_RS18420 1708b24e67e18dd61560d8463e24949b 228 SUPERFAMILY SSF141523 111 219 2.75E-21 T 06-07-2017 LK06_RS18420 1708b24e67e18dd61560d8463e24949b 228 Gene3D G3DSA:2.40.440.10 112 219 5.8E-11 T 06-07-2017 LK06_RS15675 76c68012d8e6f8ed6a66f07adae0d05e 501 SUPERFAMILY SSF52540 7 215 4.65E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15675 76c68012d8e6f8ed6a66f07adae0d05e 501 Gene3D G3DSA:1.10.10.10 271 317 3.1E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS15675 76c68012d8e6f8ed6a66f07adae0d05e 501 Gene3D G3DSA:3.40.50.300 9 182 3.2E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15675 76c68012d8e6f8ed6a66f07adae0d05e 501 SUPERFAMILY SSF46785 268 336 9.6E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03370 bc33402e07251606a6e60d4ef6045ccf 339 SUPERFAMILY SSF52540 93 313 1.15E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03370 bc33402e07251606a6e60d4ef6045ccf 339 Gene3D G3DSA:3.40.50.300 93 210 4.3E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03370 bc33402e07251606a6e60d4ef6045ccf 339 Pfam PF05621 Bacterial TniB protein 91 317 2.1E-27 T 06-07-2017 IPR008868 Bacterial TniB LK06_RS24460 4910cc0377589e523b703f3e5d4fbb8b 102 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 1.3E-52 T 06-07-2017 IPR019592 Protein of unknown function DUF2469 LK06_RS23570 0db261b8ba4c3364309281edb5abdaa4 229 Gene3D G3DSA:1.10.10.10 165 210 1.4E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23570 0db261b8ba4c3364309281edb5abdaa4 229 Gene3D G3DSA:3.40.50.2300 3 125 3.6E-28 T 06-07-2017 LK06_RS23570 0db261b8ba4c3364309281edb5abdaa4 229 SUPERFAMILY SSF52172 5 138 3.42E-31 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS23570 0db261b8ba4c3364309281edb5abdaa4 229 PIRSF PIRSF006171 5 228 4.7E-69 T 06-07-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 LK06_RS23570 0db261b8ba4c3364309281edb5abdaa4 229 Pfam PF00072 Response regulator receiver domain 9 120 2.8E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS23570 0db261b8ba4c3364309281edb5abdaa4 229 SMART SM00448 7 120 2.4E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.5E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 1.5E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.5E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.5E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.5E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.5E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 1.5E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.5E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.5E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 PIRSF PIRSF000532 1 345 1.0E-114 T 06-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 06-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 2.5E-142 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 Gene3D G3DSA:3.40.50.450 1 213 4.0E-73 T 06-07-2017 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 342 43.868 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 SUPERFAMILY SSF53784 1 332 7.59E-120 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS23555 b6a77fc92f855b739bb48169dfa8744b 346 Pfam PF00365 Phosphofructokinase 2 297 1.5E-98 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 LK06_RS11315 51ac49b7a298363236e286422b7d3214 388 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS11315 51ac49b7a298363236e286422b7d3214 388 Pfam PF00005 ABC transporter 4 150 1.8E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS11315 51ac49b7a298363236e286422b7d3214 388 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 3 351 1.3E-102 T 06-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 LK06_RS11315 51ac49b7a298363236e286422b7d3214 388 SUPERFAMILY SSF54631 237 356 2.72E-11 T 06-07-2017 LK06_RS11315 51ac49b7a298363236e286422b7d3214 388 Gene3D G3DSA:3.10.580.10 236 349 3.7E-9 T 06-07-2017 LK06_RS11315 51ac49b7a298363236e286422b7d3214 388 Gene3D G3DSA:3.40.50.300 2 224 1.3E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11315 51ac49b7a298363236e286422b7d3214 388 SMART SM00382 13 206 7.0E-21 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS11315 51ac49b7a298363236e286422b7d3214 388 SUPERFAMILY SSF52540 3 226 4.58E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 Pfam PF00742 Homoserine dehydrogenase 138 318 7.0E-68 T 06-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 SUPERFAMILY SSF55347 138 305 6.08E-54 T 06-07-2017 LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 PIRSF PIRSF000098 3 429 1.1E-159 T 06-07-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 Pfam PF01842 ACT domain 353 415 1.6E-14 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 06-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 Gene3D G3DSA:3.30.360.10 150 302 3.5E-56 T 06-07-2017 LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 Gene3D G3DSA:3.40.50.720 3 149 1.3E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 SUPERFAMILY SSF51735 4 159 1.82E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 SUPERFAMILY SSF55021 349 421 3.31E-15 T 06-07-2017 LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 Gene3D G3DSA:3.30.70.260 350 420 5.2E-12 T 06-07-2017 LK06_RS23210 85e159a85c5873764e37a99a35c8bddb 429 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 130 5.0E-23 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 LK06_RS00675 7b6811b3b33560279523542c7185fdd8 553 SMART SM00387 263 374 7.6E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00675 7b6811b3b33560279523542c7185fdd8 553 Gene3D G3DSA:3.30.565.10 266 372 7.7E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00675 7b6811b3b33560279523542c7185fdd8 553 SUPERFAMILY SSF55874 254 377 6.94E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS00675 7b6811b3b33560279523542c7185fdd8 553 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 266 372 7.8E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS01650 c6416693264a54054dea2ee487be5672 187 Gene3D G3DSA:3.40.50.620 52 187 2.8E-25 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS01650 c6416693264a54054dea2ee487be5672 187 PRINTS PR01438 Universal stress protein signature 50 68 1.9E-7 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS01650 c6416693264a54054dea2ee487be5672 187 PRINTS PR01438 Universal stress protein signature 165 187 1.9E-7 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS01650 c6416693264a54054dea2ee487be5672 187 Pfam PF00582 Universal stress protein family 51 187 1.9E-23 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS01650 c6416693264a54054dea2ee487be5672 187 SUPERFAMILY SSF52402 51 187 2.18E-24 T 06-07-2017 LK06_RS01205 cc388d76bb7a45d6f1c9b4455a957ea1 133 Pfam PF13466 STAS domain 23 102 2.1E-14 T 06-07-2017 IPR002645 STAS domain LK06_RS01205 cc388d76bb7a45d6f1c9b4455a957ea1 133 SUPERFAMILY SSF52091 15 117 1.37E-21 T 06-07-2017 IPR002645 STAS domain LK06_RS01205 cc388d76bb7a45d6f1c9b4455a957ea1 133 Gene3D G3DSA:3.30.750.24 18 118 4.2E-25 T 06-07-2017 IPR002645 STAS domain LK06_RS01205 cc388d76bb7a45d6f1c9b4455a957ea1 133 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 11 112 1.2E-25 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 LK06_RS07215 dd07c87f75b192185b77c23da6659611 556 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 55 151 1.0E-29 T 06-07-2017 IPR032093 Phospholipase D, N-terminal LK06_RS07215 dd07c87f75b192185b77c23da6659611 556 Gene3D G3DSA:3.60.21.10 171 443 1.1E-12 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS07215 dd07c87f75b192185b77c23da6659611 556 Gene3D G3DSA:3.60.21.10 478 525 1.1E-12 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS07215 dd07c87f75b192185b77c23da6659611 556 Pfam PF09423 PhoD-like phosphatase 164 521 8.3E-116 T 06-07-2017 IPR018946 Alkaline phosphatase D-related LK06_RS07215 dd07c87f75b192185b77c23da6659611 556 SUPERFAMILY SSF56300 161 526 5.06E-30 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS32210 05c305d0d0876e454065ee0bb10e85fe 60 Pfam PF12728 Helix-turn-helix domain 6 55 2.0E-11 T 06-07-2017 LK06_RS32210 05c305d0d0876e454065ee0bb10e85fe 60 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 53 8.3E-9 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 LK06_RS17065 188ed25c7a92e6d4ba082823037fd3ee 68 SUPERFAMILY SSF46955 11 59 2.61E-11 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS17065 188ed25c7a92e6d4ba082823037fd3ee 68 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 58 1.2E-8 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 LK06_RS17065 188ed25c7a92e6d4ba082823037fd3ee 68 Pfam PF12728 Helix-turn-helix domain 11 59 1.3E-11 T 06-07-2017 LK06_RS17065 188ed25c7a92e6d4ba082823037fd3ee 68 Gene3D G3DSA:1.10.1660.10 11 57 5.4E-7 T 06-07-2017 LK06_RS18710 0c33b3f638cdb8150f21e4064ac1126b 251 Hamap MF_01240 UPF0309 protein . 6 250 39.007 T 06-07-2017 IPR022951 Uncharacterised protein family UPF0309 LK06_RS18710 0c33b3f638cdb8150f21e4064ac1126b 251 SUPERFAMILY SSF53697 11 209 4.89E-21 T 06-07-2017 LK06_RS18710 0c33b3f638cdb8150f21e4064ac1126b 251 Pfam PF13580 SIS domain 10 146 8.6E-40 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 LK06_RS18710 0c33b3f638cdb8150f21e4064ac1126b 251 Gene3D G3DSA:3.40.50.10490 10 246 1.2E-68 T 06-07-2017 LK06_RS21155 dbacf3492638cf3ef4326e764db891eb 689 Pfam PF03190 Protein of unknown function, DUF255 2 161 8.2E-74 T 06-07-2017 IPR004879 Domain of unknown function DUF255 LK06_RS21155 dbacf3492638cf3ef4326e764db891eb 689 Gene3D G3DSA:1.50.10.10 189 320 9.9E-17 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 LK06_RS21155 dbacf3492638cf3ef4326e764db891eb 689 SUPERFAMILY SSF52833 3 126 2.59E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS21155 dbacf3492638cf3ef4326e764db891eb 689 SUPERFAMILY SSF48208 189 535 3.83E-72 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS21155 dbacf3492638cf3ef4326e764db891eb 689 Gene3D G3DSA:3.40.30.10 19 145 2.1E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS21155 dbacf3492638cf3ef4326e764db891eb 689 PIRSF PIRSF006402 1 678 5.1E-204 T 06-07-2017 IPR024705 Spermatogenesis-associated protein 20 LK06_RS13095 27896993891681814265a2ac7eb4e2b3 366 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 122 364 5.4E-78 T 06-07-2017 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 LK06_RS13095 27896993891681814265a2ac7eb4e2b3 366 Pfam PF01578 Cytochrome C assembly protein 145 358 5.1E-46 T 06-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 LK06_RS18595 58a687abaaf39242f1ef5468cef07597 229 Gene3D G3DSA:3.40.50.1110 3 213 1.2E-18 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS18595 58a687abaaf39242f1ef5468cef07597 229 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 201 3.1E-16 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS18595 58a687abaaf39242f1ef5468cef07597 229 SUPERFAMILY SSF52266 63 214 5.36E-22 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS18595 58a687abaaf39242f1ef5468cef07597 229 SUPERFAMILY SSF52266 2 26 5.36E-22 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS20280 591fe6eb4f2ebe65e709e192f9155ca2 331 Pfam PF00877 NlpC/P60 family 228 315 5.5E-19 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS20280 591fe6eb4f2ebe65e709e192f9155ca2 331 SUPERFAMILY SSF54001 213 317 3.14E-34 T 06-07-2017 LK06_RS20280 591fe6eb4f2ebe65e709e192f9155ca2 331 Gene3D G3DSA:3.90.1720.10 210 317 5.5E-37 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS13895 9414e2b1a290633d6040dbfdc79c37a0 377 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 160 377 6.0E-88 T 06-07-2017 LK06_RS13895 9414e2b1a290633d6040dbfdc79c37a0 377 Pfam PF10979 Protein of unknown function (DUF2786) 158 197 1.0E-15 T 06-07-2017 IPR024498 Domain of unknown function DUF2786 LK06_RS26425 37aa07d2758790800db6d11819b51b86 174 Gene3D G3DSA:3.10.450.50 19 173 7.5E-24 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS26425 37aa07d2758790800db6d11819b51b86 174 SUPERFAMILY SSF54427 24 167 7.02E-30 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS26425 37aa07d2758790800db6d11819b51b86 174 Pfam PF00866 Ring hydroxylating beta subunit 79 167 1.6E-9 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 LK06_RS11740 b33a8d2eea9918f744dc1120757a5b0d 391 Pfam PF06224 Winged helix DNA-binding domain 40 360 1.1E-66 T 06-07-2017 IPR009351 Protein of unknown function DUF1006 LK06_RS00745 51748d362b20549f55efea742e3ce24a 150 SMART SM00740 76 144 2.0E-5 T 06-07-2017 IPR005543 PASTA domain LK06_RS00745 51748d362b20549f55efea742e3ce24a 150 Pfam PF03793 PASTA domain 81 144 1.4E-5 T 06-07-2017 IPR005543 PASTA domain LK06_RS24425 84e269897de7e48e5d0812c30ab2baf2 277 Gene3D G3DSA:1.10.1270.20 168 257 7.4E-28 T 06-07-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 LK06_RS24425 84e269897de7e48e5d0812c30ab2baf2 277 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 232 3.1E-71 T 06-07-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 LK06_RS24425 84e269897de7e48e5d0812c30ab2baf2 277 SUPERFAMILY SSF75217 1 246 9.59E-83 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases LK06_RS24425 84e269897de7e48e5d0812c30ab2baf2 277 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 277 100.326 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 LK06_RS24425 84e269897de7e48e5d0812c30ab2baf2 277 Gene3D G3DSA:3.40.1280.10 1 167 1.7E-60 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LK06_RS24425 84e269897de7e48e5d0812c30ab2baf2 277 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 239 2.8E-64 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 LK06_RS24425 84e269897de7e48e5d0812c30ab2baf2 277 PIRSF PIRSF000386 1 259 7.9E-94 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 LK06_RS03705 77e7ec6045fd161cf6d39fdb3001b16e 655 Pfam PF13193 AMP-binding enzyme C-terminal domain 539 614 3.8E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS03705 77e7ec6045fd161cf6d39fdb3001b16e 655 SUPERFAMILY SSF56801 41 649 5.36E-127 T 06-07-2017 LK06_RS03705 77e7ec6045fd161cf6d39fdb3001b16e 655 ProSitePatterns PS00455 Putative AMP-binding domain signature. 269 280 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS03705 77e7ec6045fd161cf6d39fdb3001b16e 655 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 41 97 1.5E-12 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 LK06_RS03705 77e7ec6045fd161cf6d39fdb3001b16e 655 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 5 654 0.0 T 06-07-2017 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 LK06_RS03705 77e7ec6045fd161cf6d39fdb3001b16e 655 Gene3D G3DSA:3.30.300.30 525 615 4.7E-14 T 06-07-2017 LK06_RS03705 77e7ec6045fd161cf6d39fdb3001b16e 655 Gene3D G3DSA:3.40.50.980 99 274 1.1E-28 T 06-07-2017 LK06_RS03705 77e7ec6045fd161cf6d39fdb3001b16e 655 Gene3D G3DSA:3.40.50.980 275 428 1.7E-15 T 06-07-2017 LK06_RS03705 77e7ec6045fd161cf6d39fdb3001b16e 655 Pfam PF00501 AMP-binding enzyme 100 526 1.7E-46 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS17620 eff1a4e474ac0f9de7f9107e6e3fc786 281 ProSitePatterns PS00683 Rhodanese C-terminal signature. 257 267 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 LK06_RS17620 eff1a4e474ac0f9de7f9107e6e3fc786 281 Gene3D G3DSA:3.40.250.10 4 142 7.2E-37 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS17620 eff1a4e474ac0f9de7f9107e6e3fc786 281 SUPERFAMILY SSF52821 4 130 9.3E-35 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS17620 eff1a4e474ac0f9de7f9107e6e3fc786 281 Pfam PF00581 Rhodanese-like domain 151 268 6.1E-15 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS17620 eff1a4e474ac0f9de7f9107e6e3fc786 281 Pfam PF00581 Rhodanese-like domain 10 118 5.0E-17 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS17620 eff1a4e474ac0f9de7f9107e6e3fc786 281 SUPERFAMILY SSF52821 151 278 6.68E-33 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS17620 eff1a4e474ac0f9de7f9107e6e3fc786 281 SMART SM00450 8 122 2.6E-20 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS17620 eff1a4e474ac0f9de7f9107e6e3fc786 281 SMART SM00450 146 273 2.0E-20 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS17620 eff1a4e474ac0f9de7f9107e6e3fc786 281 Gene3D G3DSA:3.40.250.10 152 277 8.7E-33 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS06685 1e08e59bf67834bef916181049c33826 144 Gene3D G3DSA:1.20.1250.20 31 116 1.1E-4 T 06-07-2017 LK06_RS06685 1e08e59bf67834bef916181049c33826 144 SUPERFAMILY SSF103473 8 139 1.83E-7 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS22635 4e0950ead674ac3b0de126709a1015dd 1136 SUPERFAMILY SSF48452 786 898 9.21E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22635 4e0950ead674ac3b0de126709a1015dd 1136 SUPERFAMILY SSF48452 1018 1068 9.21E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22635 4e0950ead674ac3b0de126709a1015dd 1136 Gene3D G3DSA:1.25.40.10 989 1068 6.1E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22635 4e0950ead674ac3b0de126709a1015dd 1136 Gene3D G3DSA:1.25.40.10 785 940 6.1E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS07540 fe42983cea01bc9e90f2f16a49b68afd 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 143 6.6E-16 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase LK06_RS07540 fe42983cea01bc9e90f2f16a49b68afd 147 SUPERFAMILY SSF55961 1 144 2.09E-31 T 06-07-2017 LK06_RS07540 fe42983cea01bc9e90f2f16a49b68afd 147 Gene3D G3DSA:3.30.530.20 4 144 4.3E-17 T 06-07-2017 IPR023393 START-like domain LK06_RS13485 8381a1da325c1312244d07724063cf68 414 Gene3D G3DSA:1.20.1250.20 214 385 1.1E-17 T 06-07-2017 LK06_RS13485 8381a1da325c1312244d07724063cf68 414 SUPERFAMILY SSF103473 8 388 3.79E-27 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS13485 8381a1da325c1312244d07724063cf68 414 Pfam PF07690 Major Facilitator Superfamily 221 385 1.1E-11 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS02320 3719943346e7d84e1df764251044b92e 95 SUPERFAMILY SSF143120 5 53 8.89E-12 T 06-07-2017 LK06_RS02320 3719943346e7d84e1df764251044b92e 95 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 52 1.2E-16 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LK06_RS02320 3719943346e7d84e1df764251044b92e 95 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 58 9.1E-15 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LK06_RS02320 3719943346e7d84e1df764251044b92e 95 Gene3D G3DSA:3.40.1620.10 3 50 1.0E-14 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LK06_RS15480 0429cf524862d2ac70cae15ae8039f44 402 Pfam PF05090 Vitamin K-dependent gamma-carboxylase 242 368 3.0E-6 T 06-07-2017 IPR007782 Vitamin K-dependent gamma-carboxylase GO:0008488|GO:0017187 KEGG: 00130+4.1.1.90|Reactome: R-HSA-159740 LK06_RS15480 0429cf524862d2ac70cae15ae8039f44 402 SMART SM00752 17 361 5.6E-97 T 06-07-2017 IPR011020 HTTM Reactome: R-HSA-159740 LK06_RS15480 0429cf524862d2ac70cae15ae8039f44 402 ProDom PD031536 MEMBRANE TRANSMEMBRANE YVAX YITN 268 350 0.005 T 06-07-2017 LK06_RS20210 4c7bab9b5ad3f267359188f54a211140 537 Pfam PF00171 Aldehyde dehydrogenase family 48 501 4.4E-144 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 LK06_RS20210 4c7bab9b5ad3f267359188f54a211140 537 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 273 280 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 LK06_RS20210 4c7bab9b5ad3f267359188f54a211140 537 Gene3D G3DSA:3.40.605.10 45 287 3.6E-71 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 LK06_RS20210 4c7bab9b5ad3f267359188f54a211140 537 SUPERFAMILY SSF53720 40 504 2.09E-141 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 LK06_RS20210 4c7bab9b5ad3f267359188f54a211140 537 Gene3D G3DSA:3.40.309.10 288 465 6.4E-66 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 LK06_RS26715 5a467b995defc2a0556e94a803d71b48 151 SUPERFAMILY SSF52402 72 146 1.51E-20 T 06-07-2017 LK06_RS26715 5a467b995defc2a0556e94a803d71b48 151 Gene3D G3DSA:3.40.50.620 58 146 4.1E-12 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS17590 95641a524acb9f87718dfbeb6c9ef878 283 Pfam PF12697 Alpha/beta hydrolase family 65 269 2.2E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS17590 95641a524acb9f87718dfbeb6c9ef878 283 Gene3D G3DSA:3.40.50.1820 214 279 9.8E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS17590 95641a524acb9f87718dfbeb6c9ef878 283 Gene3D G3DSA:3.40.50.1820 34 171 9.8E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS17590 95641a524acb9f87718dfbeb6c9ef878 283 SUPERFAMILY SSF53474 214 278 9.67E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS17590 95641a524acb9f87718dfbeb6c9ef878 283 SUPERFAMILY SSF53474 48 170 9.67E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS15385 63bbfbbe0623d464441d7ed5b8985c52 413 SUPERFAMILY SSF52518 53 402 2.47E-99 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS15385 63bbfbbe0623d464441d7ed5b8985c52 413 Pfam PF00676 Dehydrogenase E1 component 90 371 1.0E-78 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 LK06_RS15385 63bbfbbe0623d464441d7ed5b8985c52 413 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 57 398 3.0E-137 T 06-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LK06_RS15385 63bbfbbe0623d464441d7ed5b8985c52 413 Gene3D G3DSA:3.40.50.970 34 398 1.8E-131 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS21780 7ec780828276ae4ed0c0eac3a1dc9a29 329 SUPERFAMILY SSF51445 98 269 1.32E-9 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS21780 7ec780828276ae4ed0c0eac3a1dc9a29 329 Gene3D G3DSA:3.20.20.80 99 271 2.4E-9 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS13770 69c4f61c52f0b927a2fa2ce99400e1dd 285 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 21 281 9.0E-89 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 LK06_RS13770 69c4f61c52f0b927a2fa2ce99400e1dd 285 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 21 36 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS13770 69c4f61c52f0b927a2fa2ce99400e1dd 285 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 55 68 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS13770 69c4f61c52f0b927a2fa2ce99400e1dd 285 SUPERFAMILY SSF51717 19 282 4.71E-91 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS13770 69c4f61c52f0b927a2fa2ce99400e1dd 285 Gene3D G3DSA:3.20.20.20 17 283 1.6E-102 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS13770 69c4f61c52f0b927a2fa2ce99400e1dd 285 Pfam PF00809 Pterin binding enzyme 22 267 1.7E-82 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LK06_RS31170 cb653fc7ba23e60dff41c70901886d79 347 SUPERFAMILY SSF51430 14 330 3.67E-86 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS31170 cb653fc7ba23e60dff41c70901886d79 347 Gene3D G3DSA:3.20.20.100 13 331 3.5E-81 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS31170 cb653fc7ba23e60dff41c70901886d79 347 Pfam PF00248 Aldo/keto reductase family 29 329 8.8E-65 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS20615 37a9e769adcec3d3610546eec7c1f647 437 SUPERFAMILY SSF53756 100 300 1.57E-6 T 06-07-2017 LK06_RS05375 e75c49ce898d433fad699798354b9550 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05375 e75c49ce898d433fad699798354b9550 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05375 e75c49ce898d433fad699798354b9550 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 2.6E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05375 e75c49ce898d433fad699798354b9550 220 SUPERFAMILY SSF46689 14 88 3.69E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS05375 e75c49ce898d433fad699798354b9550 220 Gene3D G3DSA:1.10.357.10 24 216 4.5E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS15155 bea272431ad27b1b5ebc79530541402c 167 Gene3D G3DSA:3.10.580.10 11 156 3.8E-10 T 06-07-2017 LK06_RS15155 bea272431ad27b1b5ebc79530541402c 167 SUPERFAMILY SSF54631 10 157 1.37E-14 T 06-07-2017 LK06_RS15155 bea272431ad27b1b5ebc79530541402c 167 SMART SM00116 9 57 3.4 T 06-07-2017 IPR000644 CBS domain LK06_RS15155 bea272431ad27b1b5ebc79530541402c 167 SMART SM00116 98 157 2.6 T 06-07-2017 IPR000644 CBS domain LK06_RS15155 bea272431ad27b1b5ebc79530541402c 167 Pfam PF00571 CBS domain 97 157 9.2E-5 T 06-07-2017 IPR000644 CBS domain LK06_RS15155 bea272431ad27b1b5ebc79530541402c 167 Pfam PF00571 CBS domain 10 56 0.0012 T 06-07-2017 IPR000644 CBS domain LK06_RS26755 05c15c4510853879d7576b6294d38d56 217 SUPERFAMILY SSF161098 14 196 1.44E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26755 05c15c4510853879d7576b6294d38d56 217 Gene3D G3DSA:1.10.3720.10 14 195 8.6E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26755 05c15c4510853879d7576b6294d38d56 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 205 8.2E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS31805 7bcba5178e251c32a4ae0c5edf87fe29 328 Gene3D G3DSA:2.40.440.10 166 291 1.9E-19 T 06-07-2017 LK06_RS31805 7bcba5178e251c32a4ae0c5edf87fe29 328 SUPERFAMILY SSF141523 161 290 1.1E-24 T 06-07-2017 LK06_RS31805 7bcba5178e251c32a4ae0c5edf87fe29 328 Pfam PF03734 L,D-transpeptidase catalytic domain 166 290 4.1E-17 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 LK06_RS31305 759e638d8f3e6d35b829e2f39ef3effa 195 Pfam PF01106 NifU-like domain 99 164 6.0E-11 T 06-07-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 LK06_RS31305 759e638d8f3e6d35b829e2f39ef3effa 195 SUPERFAMILY SSF117916 87 166 5.67E-9 T 06-07-2017 LK06_RS14350 599b37cd9bfb436171d1a29c1feaf7f8 234 SMART SM00448 12 119 1.8E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS14350 599b37cd9bfb436171d1a29c1feaf7f8 234 Gene3D G3DSA:3.40.50.2300 11 130 3.4E-37 T 06-07-2017 LK06_RS14350 599b37cd9bfb436171d1a29c1feaf7f8 234 SUPERFAMILY SSF52172 12 175 2.05E-40 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS14350 599b37cd9bfb436171d1a29c1feaf7f8 234 Gene3D G3DSA:1.10.10.10 131 225 8.5E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14350 599b37cd9bfb436171d1a29c1feaf7f8 234 Pfam PF00072 Response regulator receiver domain 14 120 4.2E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS14350 599b37cd9bfb436171d1a29c1feaf7f8 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 224 2.0E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS14350 599b37cd9bfb436171d1a29c1feaf7f8 234 SMART SM00862 152 224 1.3E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS10175 5adb3e59522019c6e631afc3ec336e85 334 Gene3D G3DSA:3.40.50.150 30 251 4.6E-62 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS10175 5adb3e59522019c6e631afc3ec336e85 334 SUPERFAMILY SSF53335 32 212 3.04E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS10175 5adb3e59522019c6e631afc3ec336e85 334 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 72 215 2.1E-26 T 06-07-2017 LK06_RS04320 5ae426fd8394fc3cb7168b0149da7631 387 Pfam PF13439 Glycosyltransferase Family 4 14 173 3.7E-34 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS04320 5ae426fd8394fc3cb7168b0149da7631 387 SUPERFAMILY SSF53756 2 363 8.57E-85 T 06-07-2017 LK06_RS04320 5ae426fd8394fc3cb7168b0149da7631 387 Gene3D G3DSA:3.40.50.2000 185 339 1.1E-26 T 06-07-2017 LK06_RS04320 5ae426fd8394fc3cb7168b0149da7631 387 Pfam PF13692 Glycosyl transferases group 1 188 328 8.6E-30 T 06-07-2017 LK06_RS00680 e2318725812493ab0851955bfcf9ad0f 135 SUPERFAMILY SSF103196 5 133 2.09E-32 T 06-07-2017 LK06_RS00680 e2318725812493ab0851955bfcf9ad0f 135 Gene3D G3DSA:3.30.450.30 8 131 8.3E-29 T 06-07-2017 LK06_RS00680 e2318725812493ab0851955bfcf9ad0f 135 Pfam PF03259 Roadblock/LC7 domain 12 104 1.2E-22 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS00680 e2318725812493ab0851955bfcf9ad0f 135 SMART SM00960 12 104 2.0E-25 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS23080 dfd03f4f7cefcc83f608c3e2f3cf27ab 180 Gene3D G3DSA:2.140.10.10 34 143 7.0E-8 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS23080 dfd03f4f7cefcc83f608c3e2f3cf27ab 180 SUPERFAMILY SSF50998 32 160 8.95E-6 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS30825 cea75a0b1ad435106f595c844e99e7cc 398 Pfam PF01494 FAD binding domain 127 310 9.2E-10 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS30825 cea75a0b1ad435106f595c844e99e7cc 398 SUPERFAMILY SSF51905 2 147 3.11E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30825 cea75a0b1ad435106f595c844e99e7cc 398 SUPERFAMILY SSF51905 244 346 3.11E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30825 cea75a0b1ad435106f595c844e99e7cc 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 257 272 3.3E-9 T 06-07-2017 LK06_RS30825 cea75a0b1ad435106f595c844e99e7cc 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 288 3.3E-9 T 06-07-2017 LK06_RS30825 cea75a0b1ad435106f595c844e99e7cc 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.3E-9 T 06-07-2017 LK06_RS30825 cea75a0b1ad435106f595c844e99e7cc 398 Gene3D G3DSA:3.50.50.60 1 42 3.7E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30825 cea75a0b1ad435106f595c844e99e7cc 398 Gene3D G3DSA:3.50.50.60 247 340 3.7E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS30825 cea75a0b1ad435106f595c844e99e7cc 398 Gene3D G3DSA:3.50.50.60 96 163 3.7E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS21490 205207f72ab6d0783f181c672670f40a 175 Pfam PF14030 Protein of unknown function (DUF4245) 8 172 9.5E-48 T 06-07-2017 IPR025339 Protein of unknown function DUF4245 LK06_RS23140 bd8d02d04193c76f305f33f2806feec5 606 SUPERFAMILY SSF52540 281 389 2.46E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23140 bd8d02d04193c76f305f33f2806feec5 606 SUPERFAMILY SSF52540 443 602 2.46E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23140 bd8d02d04193c76f305f33f2806feec5 606 Gene3D G3DSA:3.40.50.300 283 320 5.7E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23140 bd8d02d04193c76f305f33f2806feec5 606 Gene3D G3DSA:3.40.50.300 355 392 5.7E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23140 bd8d02d04193c76f305f33f2806feec5 606 Gene3D G3DSA:3.40.50.300 484 601 5.7E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01885 cc9131f19b981af06a1187502bd5c80e 336 Pfam PF00355 Rieske [2Fe-2S] domain 52 121 3.6E-10 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS01885 cc9131f19b981af06a1187502bd5c80e 336 Gene3D G3DSA:2.102.10.10 52 146 3.9E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS01885 cc9131f19b981af06a1187502bd5c80e 336 SUPERFAMILY SSF50022 49 146 2.1E-19 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LK06_RS27570 be90c784764c8a92439bb3653d7d9798 245 SMART SM00866 98 236 1.3E-33 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS27570 be90c784764c8a92439bb3653d7d9798 245 SMART SM00345 19 78 3.2E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS27570 be90c784764c8a92439bb3653d7d9798 245 SUPERFAMILY SSF64288 66 240 2.98E-45 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS27570 be90c784764c8a92439bb3653d7d9798 245 SUPERFAMILY SSF46785 8 82 4.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27570 be90c784764c8a92439bb3653d7d9798 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 3.9E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS27570 be90c784764c8a92439bb3653d7d9798 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 3.9E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS27570 be90c784764c8a92439bb3653d7d9798 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 9.4E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS27570 be90c784764c8a92439bb3653d7d9798 245 Pfam PF07702 UTRA domain 99 235 4.6E-36 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS27570 be90c784764c8a92439bb3653d7d9798 245 Gene3D G3DSA:3.40.1410.10 81 239 2.0E-46 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS27570 be90c784764c8a92439bb3653d7d9798 245 Gene3D G3DSA:1.10.10.10 8 80 4.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18770 c8dea43ee2ed50232b20af9379fc7638 196 Pfam PF04542 Sigma-70 region 2 29 95 1.4E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS18770 c8dea43ee2ed50232b20af9379fc7638 196 Gene3D G3DSA:1.10.10.10 133 181 9.3E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18770 c8dea43ee2ed50232b20af9379fc7638 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 180 4.9E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS18770 c8dea43ee2ed50232b20af9379fc7638 196 SUPERFAMILY SSF88946 11 95 7.59E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS18770 c8dea43ee2ed50232b20af9379fc7638 196 SUPERFAMILY SSF88659 129 181 5.23E-6 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS18770 c8dea43ee2ed50232b20af9379fc7638 196 Gene3D G3DSA:1.10.1740.10 11 111 6.8E-15 T 06-07-2017 LK06_RS07060 6ce240750c69b996871f9de065957d07 258 Pfam PF13462 Thioredoxin 84 253 1.7E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS07060 6ce240750c69b996871f9de065957d07 258 SUPERFAMILY SSF52833 78 253 2.07E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS07060 6ce240750c69b996871f9de065957d07 258 Gene3D G3DSA:3.40.30.10 86 253 4.4E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS01910 ba14d81841d642951816f0f82bdd1232 520 SUPERFAMILY SSF51905 34 353 6.8E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01910 ba14d81841d642951816f0f82bdd1232 520 SUPERFAMILY SSF51905 447 490 6.8E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01910 ba14d81841d642951816f0f82bdd1232 520 PRINTS PR00419 Adrenodoxin reductase family signature 60 73 6.4E-6 T 06-07-2017 LK06_RS01910 ba14d81841d642951816f0f82bdd1232 520 PRINTS PR00419 Adrenodoxin reductase family signature 37 59 6.4E-6 T 06-07-2017 LK06_RS01910 ba14d81841d642951816f0f82bdd1232 520 Pfam PF01593 Flavin containing amine oxidoreductase 45 487 1.1E-37 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 LK06_RS01910 ba14d81841d642951816f0f82bdd1232 520 Gene3D G3DSA:3.50.50.60 246 330 1.6E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01910 ba14d81841d642951816f0f82bdd1232 520 Gene3D G3DSA:3.50.50.60 179 195 1.6E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01910 ba14d81841d642951816f0f82bdd1232 520 Gene3D G3DSA:3.50.50.60 34 117 1.6E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS01910 ba14d81841d642951816f0f82bdd1232 520 Gene3D G3DSA:3.50.50.60 434 488 1.6E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS04070 effdeeca1f4906ef1eb5dbf886d8935d 714 Hamap MF_00983 Probable primosomal protein N' [priA]. 56 713 20.92 T 06-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 LK06_RS04070 effdeeca1f4906ef1eb5dbf886d8935d 714 Gene3D G3DSA:3.40.50.300 227 323 1.8E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04070 effdeeca1f4906ef1eb5dbf886d8935d 714 SUPERFAMILY SSF52540 224 313 2.97E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16080 e995de03ebb2ace3ef5544f71f8d4c9b 105 SUPERFAMILY SSF51182 25 103 2.9E-20 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS16080 e995de03ebb2ace3ef5544f71f8d4c9b 105 Gene3D G3DSA:2.60.120.10 2 104 3.8E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS16080 e995de03ebb2ace3ef5544f71f8d4c9b 105 Pfam PF07883 Cupin domain 33 100 3.2E-14 T 06-07-2017 IPR013096 Cupin 2, conserved barrel LK06_RS08340 4898cde24221ecd91978da9c77dba1de 108 SUPERFAMILY SSF54427 12 103 1.12E-11 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS08340 4898cde24221ecd91978da9c77dba1de 108 Gene3D G3DSA:3.10.450.50 12 104 8.6E-11 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS27505 78ab945ad0afd14e32c9393565f69325 238 Pfam PF00665 Integrase core domain 67 181 6.5E-28 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 LK06_RS27505 78ab945ad0afd14e32c9393565f69325 238 SUPERFAMILY SSF53098 62 223 1.39E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS27505 78ab945ad0afd14e32c9393565f69325 238 Pfam PF13276 HTH-like domain 3 43 1.0E-8 T 06-07-2017 IPR025948 HTH-like domain LK06_RS27505 78ab945ad0afd14e32c9393565f69325 238 Gene3D G3DSA:3.30.420.10 62 221 6.9E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS06495 823f451037b0c8229cf0920a015641df 301 Pfam PF00005 ABC transporter 24 154 8.5E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS06495 823f451037b0c8229cf0920a015641df 301 SUPERFAMILY SSF52540 1 214 5.42E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06495 823f451037b0c8229cf0920a015641df 301 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS06495 823f451037b0c8229cf0920a015641df 301 Gene3D G3DSA:3.40.50.300 1 214 3.2E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06495 823f451037b0c8229cf0920a015641df 301 SMART SM00382 24 210 2.7E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS30040 cc5498d1806b311f516d87e4a6618dee 412 Gene3D G3DSA:1.10.10.10 31 91 8.0E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30040 cc5498d1806b311f516d87e4a6618dee 412 SUPERFAMILY SSF53067 227 407 1.77E-33 T 06-07-2017 LK06_RS30040 cc5498d1806b311f516d87e4a6618dee 412 Pfam PF00480 ROK family 108 399 1.3E-32 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS30040 cc5498d1806b311f516d87e4a6618dee 412 Gene3D G3DSA:3.30.420.40 94 240 2.8E-23 T 06-07-2017 LK06_RS30040 cc5498d1806b311f516d87e4a6618dee 412 SUPERFAMILY SSF53067 95 224 1.88E-14 T 06-07-2017 LK06_RS30040 cc5498d1806b311f516d87e4a6618dee 412 Gene3D G3DSA:3.30.420.40 241 382 2.3E-34 T 06-07-2017 LK06_RS07180 380f86c98d9ee7703acaef3e2ca702d0 273 Pfam PF01061 ABC-2 type transporter 49 233 3.4E-12 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS27555 bbd4f9c36509e702c78627da076c7929 208 SUPERFAMILY SSF53597 5 181 1.23E-24 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 LK06_RS27555 bbd4f9c36509e702c78627da076c7929 208 Pfam PF01872 RibD C-terminal domain 3 176 3.8E-22 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 LK06_RS27555 bbd4f9c36509e702c78627da076c7929 208 Gene3D G3DSA:3.40.430.10 3 188 1.5E-25 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 LK06_RS02390 0da6e1ec7b647693aba05c0bbe8e4254 230 Gene3D G3DSA:3.40.50.150 24 196 2.3E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS02390 0da6e1ec7b647693aba05c0bbe8e4254 230 SUPERFAMILY SSF53335 35 220 3.79E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS02390 0da6e1ec7b647693aba05c0bbe8e4254 230 Pfam PF08241 Methyltransferase domain 55 147 7.1E-17 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS12355 b34b20b767d394937611ca463e66665e 211 SUPERFAMILY SSF52200 5 136 4.97E-9 T 06-07-2017 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 LK06_RS12355 b34b20b767d394937611ca463e66665e 211 Pfam PF13676 TIR domain 5 114 1.5E-14 T 06-07-2017 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 294 57.102 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 289 1.0E-84 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 PIRSF PIRSF001365 7 298 1.2E-79 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 47 64 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 SMART SM01130 10 295 4.4E-118 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 Pfam PF00701 Dihydrodipicolinate synthetase family 11 292 1.1E-83 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 SUPERFAMILY SSF51569 7 289 8.69E-94 T 06-07-2017 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 Gene3D G3DSA:3.20.20.70 9 294 4.6E-106 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 1.7E-31 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 1.7E-31 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 1.7E-31 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS24915 bdf3a96e657b19dfabd7f67f448ca370 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 1.7E-31 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS28075 228742c1c3898fa16796202a89464be7 225 Gene3D G3DSA:3.50.50.60 1 69 2.8E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS28075 228742c1c3898fa16796202a89464be7 225 SUPERFAMILY SSF51905 1 67 2.59E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS28075 228742c1c3898fa16796202a89464be7 225 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 60 5.1E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS22880 0adbe70f3eb53bba26e841b26f729ad4 509 SUPERFAMILY SSF54631 283 391 4.3E-18 T 06-07-2017 LK06_RS22880 0adbe70f3eb53bba26e841b26f729ad4 509 SMART SM00116 284 332 7.2E-7 T 06-07-2017 IPR000644 CBS domain LK06_RS22880 0adbe70f3eb53bba26e841b26f729ad4 509 Gene3D G3DSA:3.10.580.10 283 392 1.7E-15 T 06-07-2017 LK06_RS22880 0adbe70f3eb53bba26e841b26f729ad4 509 Pfam PF00571 CBS domain 284 332 7.1E-5 T 06-07-2017 IPR000644 CBS domain LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 Gene3D G3DSA:2.40.30.10 46 140 4.5E-27 T 06-07-2017 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 272 340 8.4E-11 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 Gene3D G3DSA:3.40.50.80 146 251 3.5E-25 T 06-07-2017 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 300 308 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 PRINTS PR00409 Phthalate dioxygenase reductase family signature 116 130 2.0E-30 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 PRINTS PR00409 Phthalate dioxygenase reductase family signature 226 234 2.0E-30 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 PRINTS PR00409 Phthalate dioxygenase reductase family signature 151 170 2.0E-30 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 PRINTS PR00409 Phthalate dioxygenase reductase family signature 70 80 2.0E-30 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 PRINTS PR00409 Phthalate dioxygenase reductase family signature 92 106 2.0E-30 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 PRINTS PR00409 Phthalate dioxygenase reductase family signature 80 92 2.0E-30 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 Gene3D G3DSA:3.10.20.30 252 347 3.1E-25 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 SUPERFAMILY SSF63380 47 140 1.21E-23 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 SUPERFAMILY SSF52343 138 257 9.95E-25 T 06-07-2017 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 SUPERFAMILY SSF54292 248 347 4.59E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LK06_RS08075 72fa63626397cc03c7ef58e9ff422537 349 Pfam PF00175 Oxidoreductase NAD-binding domain 152 240 4.0E-7 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LK06_RS11850 5cc9d3164797da9786478a131896a6d6 326 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 287 1.6E-38 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LK06_RS11850 5cc9d3164797da9786478a131896a6d6 326 SUPERFAMILY SSF160240 225 295 1.29E-7 T 06-07-2017 LK06_RS11850 5cc9d3164797da9786478a131896a6d6 326 Gene3D G3DSA:3.30.70.1350 224 298 4.9E-6 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain LK06_RS11850 5cc9d3164797da9786478a131896a6d6 326 Pfam PF01545 Cation efflux family 11 218 2.8E-34 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LK06_RS11850 5cc9d3164797da9786478a131896a6d6 326 Gene3D G3DSA:1.20.1510.10 8 218 5.8E-32 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain LK06_RS11850 5cc9d3164797da9786478a131896a6d6 326 SUPERFAMILY SSF161111 6 219 3.92E-37 T 06-07-2017 LK06_RS20435 5cbddedd0d46e2f8dac1c8939d59e763 241 SUPERFAMILY SSF51621 7 238 2.6E-46 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS20435 5cbddedd0d46e2f8dac1c8939d59e763 241 Pfam PF13714 Phosphoenolpyruvate phosphomutase 7 237 6.9E-60 T 06-07-2017 LK06_RS20435 5cbddedd0d46e2f8dac1c8939d59e763 241 Gene3D G3DSA:3.20.20.60 3 221 1.3E-52 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS24840 6f93ec9118e8cec00c52f6d670514cca 386 PRINTS PR00723 Subtilisin serine protease family (S8) signature 76 89 6.7E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS24840 6f93ec9118e8cec00c52f6d670514cca 386 PRINTS PR00723 Subtilisin serine protease family (S8) signature 239 255 6.7E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS24840 6f93ec9118e8cec00c52f6d670514cca 386 PRINTS PR00723 Subtilisin serine protease family (S8) signature 37 56 6.7E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related LK06_RS24840 6f93ec9118e8cec00c52f6d670514cca 386 Gene3D G3DSA:3.40.50.200 16 300 8.3E-71 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS24840 6f93ec9118e8cec00c52f6d670514cca 386 Pfam PF00082 Subtilase family 37 291 1.7E-42 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS24840 6f93ec9118e8cec00c52f6d670514cca 386 SUPERFAMILY SSF52743 16 300 2.88E-69 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 47 294 5.3E-74 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 Pfam PF02355 Protein export membrane protein 111 303 3.6E-65 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 Gene3D G3DSA:1.20.1640.10 106 306 2.4E-18 T 06-07-2017 LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 Pfam PF07549 SecD/SecF GG Motif 41 60 5.0E-4 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 SUPERFAMILY SSF82866 125 305 4.84E-28 T 06-07-2017 LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 305 24.165 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 PRINTS PR01755 Bacterial translocase SecF protein signature 237 252 3.5E-21 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 PRINTS PR01755 Bacterial translocase SecF protein signature 202 220 3.5E-21 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 PRINTS PR01755 Bacterial translocase SecF protein signature 45 60 3.5E-21 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 PRINTS PR01755 Bacterial translocase SecF protein signature 154 168 3.5E-21 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LK06_RS04265 7a8fb5bc32e8bb79ffbbba8eb027e66e 367 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 81 291 3.1E-50 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LK06_RS13000 9c10b9b78c61be8a7a1c5b71eba74f60 246 Pfam PF06259 Alpha/beta hydrolase 168 246 4.8E-9 T 06-07-2017 IPR010427 Protein of unknown function DUF1023 LK06_RS14320 9ddd523bc8192696be9c98e39fe24e8c 253 Pfam PF07987 Domain of unkown function (DUF1775) 32 177 2.2E-44 T 06-07-2017 IPR012533 GLE1, N-terminal, bacteria LK06_RS28675 5bbf734fdccaaead3fcd4eeabce1433d 197 Gene3D G3DSA:3.90.79.10 21 183 3.7E-48 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS28675 5bbf734fdccaaead3fcd4eeabce1433d 197 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 24 178 2.2E-35 T 06-07-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 LK06_RS28675 5bbf734fdccaaead3fcd4eeabce1433d 197 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 20 191 31.204 T 06-07-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 LK06_RS28675 5bbf734fdccaaead3fcd4eeabce1433d 197 SUPERFAMILY SSF55811 23 182 2.09E-42 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS28675 5bbf734fdccaaead3fcd4eeabce1433d 197 PIRSF PIRSF018427 2 194 1.1E-51 T 06-07-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 LK06_RS28675 5bbf734fdccaaead3fcd4eeabce1433d 197 Pfam PF00293 NUDIX domain 47 172 4.6E-24 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS06905 0c94a6e61c2ff12a1ffb79476c6f9b9e 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 293 2.1E-47 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 LK06_RS06905 0c94a6e61c2ff12a1ffb79476c6f9b9e 309 SUPERFAMILY SSF81345 47 215 1.96E-5 T 06-07-2017 IPR029022 ABC transporter, BtuC-like LK06_RS14555 21816b7d0269dd6406f674b352932907 181 Pfam PF12802 MarR family 46 105 9.9E-8 T 06-07-2017 LK06_RS14555 21816b7d0269dd6406f674b352932907 181 SUPERFAMILY SSF46785 33 139 8.16E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14555 21816b7d0269dd6406f674b352932907 181 Gene3D G3DSA:1.10.10.10 32 108 1.4E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS07385 289f57a80a704c7115f0a51a4794bc5e 694 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 477 681 4.3E-71 T 06-07-2017 IPR017501 Phage infection protein, YhgE, C-terminal LK06_RS07385 289f57a80a704c7115f0a51a4794bc5e 694 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 2.9E-58 T 06-07-2017 IPR017500 Phage infection protein, YhgE, N-terminal LK06_RS07385 289f57a80a704c7115f0a51a4794bc5e 694 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 217 244 1.6E-6 T 06-07-2017 IPR023908 xxxLxxG heptad repeat LK06_RS07385 289f57a80a704c7115f0a51a4794bc5e 694 Pfam PF12698 ABC-2 family transporter protein 24 158 1.6E-8 T 06-07-2017 LK06_RS07385 289f57a80a704c7115f0a51a4794bc5e 694 Pfam PF12698 ABC-2 family transporter protein 489 674 2.5E-15 T 06-07-2017 LK06_RS13620 8eb1aec86c28470ab698e5827ec974fc 234 SMART SM00862 161 232 2.0E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS13620 8eb1aec86c28470ab698e5827ec974fc 234 Gene3D G3DSA:1.10.10.10 141 233 6.6E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13620 8eb1aec86c28470ab698e5827ec974fc 234 SMART SM00448 5 115 1.4E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS13620 8eb1aec86c28470ab698e5827ec974fc 234 SUPERFAMILY SSF52172 3 124 5.27E-40 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS13620 8eb1aec86c28470ab698e5827ec974fc 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 232 3.2E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS13620 8eb1aec86c28470ab698e5827ec974fc 234 Pfam PF00072 Response regulator receiver domain 7 116 5.3E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS13620 8eb1aec86c28470ab698e5827ec974fc 234 Gene3D G3DSA:3.40.50.2300 3 121 5.1E-39 T 06-07-2017 LK06_RS13620 8eb1aec86c28470ab698e5827ec974fc 234 SUPERFAMILY SSF46894 137 232 1.33E-28 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 227 241 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 Pfam PF00459 Inositol monophosphatase family 20 257 6.8E-58 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 Gene3D G3DSA:3.40.190.80 174 275 5.1E-19 T 06-07-2017 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 Gene3D G3DSA:3.30.540.10 19 173 1.6E-36 T 06-07-2017 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 51 71 2.4E-23 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 73 89 2.4E-23 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 193 214 2.4E-23 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 149 172 2.4E-23 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 224 248 2.4E-23 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 100 116 2.4E-23 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 SUPERFAMILY SSF56655 23 265 3.4E-60 T 06-07-2017 LK06_RS27880 ec3c4ba101fee93a37496117cd75addd 281 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 100 113 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site LK06_RS03320 773b64a83b7a63c9aca427076db967a8 332 SUPERFAMILY SSF103481 218 318 3.53E-11 T 06-07-2017 LK06_RS03320 773b64a83b7a63c9aca427076db967a8 332 SUPERFAMILY SSF103481 71 169 4.71E-10 T 06-07-2017 LK06_RS03320 773b64a83b7a63c9aca427076db967a8 332 Pfam PF00892 EamA-like transporter family 180 315 6.2E-20 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS03320 773b64a83b7a63c9aca427076db967a8 332 Pfam PF00892 EamA-like transporter family 42 168 2.8E-17 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS05675 97c2a31e157d3bd5d1544be90f0e8d41 240 Gene3D G3DSA:3.90.79.10 6 143 1.2E-39 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS05675 97c2a31e157d3bd5d1544be90f0e8d41 240 SUPERFAMILY SSF55811 11 146 4.87E-26 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS05675 97c2a31e157d3bd5d1544be90f0e8d41 240 Gene3D G3DSA:1.10.10.10 179 219 5.4E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05675 97c2a31e157d3bd5d1544be90f0e8d41 240 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS05675 97c2a31e157d3bd5d1544be90f0e8d41 240 Pfam PF00293 NUDIX domain 17 116 3.1E-15 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS22710 7350787311338ef3124a4b3d9d8ad3df 170 SMART SM00960 20 125 5.7E-13 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS22710 7350787311338ef3124a4b3d9d8ad3df 170 Gene3D G3DSA:3.30.450.30 14 51 1.5E-4 T 06-07-2017 LK06_RS22710 7350787311338ef3124a4b3d9d8ad3df 170 Gene3D G3DSA:3.30.450.30 74 149 3.4E-8 T 06-07-2017 LK06_RS22710 7350787311338ef3124a4b3d9d8ad3df 170 Pfam PF03259 Roadblock/LC7 domain 73 123 2.8E-6 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS22710 7350787311338ef3124a4b3d9d8ad3df 170 SUPERFAMILY SSF103196 14 153 8.89E-19 T 06-07-2017 LK06_RS14415 566f37fd2ad58bbe7246acafdc041db2 95 Pfam PF02583 Metal-sensitive transcriptional repressor 11 85 5.2E-26 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 LK06_RS17765 1b9176d439b97e3d2091c487884257b2 158 SMART SM00530 12 67 1.0E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS17765 1b9176d439b97e3d2091c487884257b2 158 Pfam PF01381 Helix-turn-helix 13 65 8.2E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS17765 1b9176d439b97e3d2091c487884257b2 158 SUPERFAMILY SSF47413 8 69 1.85E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS17765 1b9176d439b97e3d2091c487884257b2 158 Gene3D G3DSA:1.10.260.40 8 110 4.4E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS04955 d95c0bed1e476e4d0066753e0221fcb9 299 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 249 16.255 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LK06_RS04955 d95c0bed1e476e4d0066753e0221fcb9 299 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 3 235 1.7E-53 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LK06_RS04955 d95c0bed1e476e4d0066753e0221fcb9 299 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 112 138 8.1E-34 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LK06_RS04955 d95c0bed1e476e4d0066753e0221fcb9 299 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 162 190 8.1E-34 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LK06_RS04955 d95c0bed1e476e4d0066753e0221fcb9 299 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 2 29 8.1E-34 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LK06_RS04955 d95c0bed1e476e4d0066753e0221fcb9 299 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 94 112 8.1E-34 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LK06_RS04955 d95c0bed1e476e4d0066753e0221fcb9 299 Pfam PF00902 Sec-independent protein translocase protein (TatC) 5 230 2.9E-60 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LK06_RS00465 2dba2f7bcf2ad6d9235ff7fe26d41f10 322 Gene3D G3DSA:3.40.50.1100 75 319 5.6E-71 T 06-07-2017 LK06_RS00465 2dba2f7bcf2ad6d9235ff7fe26d41f10 322 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 308 2.1E-76 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS00465 2dba2f7bcf2ad6d9235ff7fe26d41f10 322 SUPERFAMILY SSF53686 9 317 1.2E-93 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS09725 3177fcafa6489892ccad86b511e7eaf3 74 Pfam PF12728 Helix-turn-helix domain 19 68 8.5E-10 T 06-07-2017 LK06_RS14135 6f5bdb7ee7daec66472c8f55cf87a27c 274 Gene3D G3DSA:3.30.460.10 38 90 4.6E-9 T 06-07-2017 LK06_RS14135 6f5bdb7ee7daec66472c8f55cf87a27c 274 SUPERFAMILY SSF81301 29 82 9.09E-8 T 06-07-2017 LK06_RS16060 835010f7f12b3d52565af1e4f348fc4b 301 Pfam PF03466 LysR substrate binding domain 86 296 2.1E-24 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS16060 835010f7f12b3d52565af1e4f348fc4b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS16060 835010f7f12b3d52565af1e4f348fc4b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS16060 835010f7f12b3d52565af1e4f348fc4b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS16060 835010f7f12b3d52565af1e4f348fc4b 301 Gene3D G3DSA:3.40.190.10 91 174 3.7E-6 T 06-07-2017 LK06_RS16060 835010f7f12b3d52565af1e4f348fc4b 301 Gene3D G3DSA:3.40.190.10 175 261 6.1E-13 T 06-07-2017 LK06_RS16060 835010f7f12b3d52565af1e4f348fc4b 301 Gene3D G3DSA:1.10.10.10 1 80 7.5E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16060 835010f7f12b3d52565af1e4f348fc4b 301 SUPERFAMILY SSF46785 1 77 2.18E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS16060 835010f7f12b3d52565af1e4f348fc4b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.5E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS16060 835010f7f12b3d52565af1e4f348fc4b 301 SUPERFAMILY SSF53850 82 296 2.17E-22 T 06-07-2017 LK06_RS02945 f97e36402b668bfc058581a7722ad13a 702 SUPERFAMILY SSF89372 410 672 4.58E-13 T 06-07-2017 LK06_RS02380 01fb936744f6c2e44e4cd1a341294e9e 238 PIRSF PIRSF006755 1 207 1.6E-35 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 LK06_RS02380 01fb936744f6c2e44e4cd1a341294e9e 238 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 169 4.0E-30 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 LK06_RS02380 01fb936744f6c2e44e4cd1a341294e9e 238 Gene3D G3DSA:3.40.50.300 1 204 6.0E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02380 01fb936744f6c2e44e4cd1a341294e9e 238 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 202 23.472 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 LK06_RS02380 01fb936744f6c2e44e4cd1a341294e9e 238 SUPERFAMILY SSF52540 1 201 1.93E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS02380 01fb936744f6c2e44e4cd1a341294e9e 238 Pfam PF13500 AAA domain 4 201 2.4E-32 T 06-07-2017 LK06_RS30145 f656cdf4007f1839220577c91fe084a9 533 Pfam PF00795 Carbon-nitrogen hydrolase 304 489 1.4E-15 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS30145 f656cdf4007f1839220577c91fe084a9 533 Gene3D G3DSA:3.60.110.10 236 504 5.4E-33 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS30145 f656cdf4007f1839220577c91fe084a9 533 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 26 510 15.021 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 LK06_RS30145 f656cdf4007f1839220577c91fe084a9 533 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 79 472 1.4E-74 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 LK06_RS30145 f656cdf4007f1839220577c91fe084a9 533 SUPERFAMILY SSF56317 237 504 1.01E-37 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 LK06_RS13765 da729802ee3ec09e7b9533a99b8e148c 604 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 22 220 2.2E-12 T 06-07-2017 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 LK06_RS13765 da729802ee3ec09e7b9533a99b8e148c 604 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 245 551 3.0E-107 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal LK06_RS27265 645462f837f750643d6266ef75d53441 234 Gene3D G3DSA:3.30.870.10 3 126 3.4E-6 T 06-07-2017 LK06_RS27265 645462f837f750643d6266ef75d53441 234 Gene3D G3DSA:1.10.10.10 148 192 8.3E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS27265 645462f837f750643d6266ef75d53441 234 SUPERFAMILY SSF56024 3 126 2.2E-6 T 06-07-2017 LK06_RS27265 645462f837f750643d6266ef75d53441 234 SUPERFAMILY SSF46894 148 193 2.11E-7 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS10805 2e6422fdba91491fc66673a919f80735 351 Gene3D G3DSA:3.40.50.2300 189 325 3.5E-54 T 06-07-2017 LK06_RS10805 2e6422fdba91491fc66673a919f80735 351 SUPERFAMILY SSF53822 74 350 1.26E-70 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS10805 2e6422fdba91491fc66673a919f80735 351 Pfam PF13377 Periplasmic binding protein-like domain 184 351 3.3E-35 T 06-07-2017 LK06_RS10805 2e6422fdba91491fc66673a919f80735 351 SMART SM00354 13 83 4.0E-29 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS10805 2e6422fdba91491fc66673a919f80735 351 Gene3D G3DSA:3.40.50.2300 66 188 7.5E-35 T 06-07-2017 LK06_RS10805 2e6422fdba91491fc66673a919f80735 351 SUPERFAMILY SSF47413 13 71 5.38E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10805 2e6422fdba91491fc66673a919f80735 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 2.3E-18 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LK06_RS10805 2e6422fdba91491fc66673a919f80735 351 Gene3D G3DSA:1.10.260.40 14 65 4.0E-24 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10805 2e6422fdba91491fc66673a919f80735 351 ProSitePatterns PS00356 LacI-type HTH domain signature. 16 34 - T 06-07-2017 LK06_RS06505 15f34a21bcbd11eb6a08341decc39651 336 Pfam PF02628 Cytochrome oxidase assembly protein 36 303 4.1E-17 T 06-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 LK06_RS07450 f1f022341761123520b505f79e3043fa 292 Pfam PF01261 Xylose isomerase-like TIM barrel 29 249 9.0E-26 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS07450 f1f022341761123520b505f79e3043fa 292 Gene3D G3DSA:3.20.20.150 12 290 2.7E-80 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS07450 f1f022341761123520b505f79e3043fa 292 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 185 192 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 LK06_RS07450 f1f022341761123520b505f79e3043fa 292 SUPERFAMILY SSF51658 13 289 2.62E-69 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain LK06_RS07450 f1f022341761123520b505f79e3043fa 292 SMART SM00518 12 290 9.0E-117 T 06-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 LK06_RS07450 f1f022341761123520b505f79e3043fa 292 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 225 241 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 LK06_RS07450 f1f022341761123520b505f79e3043fa 292 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 76 84 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 LK06_RS07450 f1f022341761123520b505f79e3043fa 292 Hamap MF_00152 Probable endonuclease 4 [nfo]. 11 290 39.363 T 06-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 LK06_RS07450 f1f022341761123520b505f79e3043fa 292 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 13 288 8.6E-62 T 06-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 LK06_RS19300 38a26f71e43825f8d213b852d86434c4 507 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 436 5.2E-70 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS19300 38a26f71e43825f8d213b852d86434c4 507 Pfam PF07690 Major Facilitator Superfamily 27 428 4.0E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS19300 38a26f71e43825f8d213b852d86434c4 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 6.7E-7 T 06-07-2017 LK06_RS19300 38a26f71e43825f8d213b852d86434c4 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 6.7E-7 T 06-07-2017 LK06_RS19300 38a26f71e43825f8d213b852d86434c4 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 6.7E-7 T 06-07-2017 LK06_RS19300 38a26f71e43825f8d213b852d86434c4 507 Gene3D G3DSA:1.20.1250.20 18 206 2.7E-31 T 06-07-2017 LK06_RS19300 38a26f71e43825f8d213b852d86434c4 507 SUPERFAMILY SSF103473 263 486 7.72E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS19300 38a26f71e43825f8d213b852d86434c4 507 SUPERFAMILY SSF103473 14 212 7.72E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS19300 38a26f71e43825f8d213b852d86434c4 507 Gene3D G3DSA:1.20.1250.20 280 487 1.8E-12 T 06-07-2017 LK06_RS08000 a7e87d525bf5bd96159a9d2f71e3cdab 306 Pfam PF01435 Peptidase family M48 77 290 5.3E-34 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LK06_RS08000 a7e87d525bf5bd96159a9d2f71e3cdab 306 Hamap MF_00188 Protease HtpX [htpX]. 7 292 25.605 T 06-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 LK06_RS08000 a7e87d525bf5bd96159a9d2f71e3cdab 306 Gene3D G3DSA:3.30.2010.10 67 156 4.1E-31 T 06-07-2017 LK06_RS18115 808eeff8561d4b0f17e5f5818b94c89d 345 Gene3D G3DSA:3.30.2010.10 106 182 4.7E-16 T 06-07-2017 LK06_RS18115 808eeff8561d4b0f17e5f5818b94c89d 345 Pfam PF01435 Peptidase family M48 109 181 3.5E-11 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LK06_RS05290 1f35d4cf79fefa3b55ebabd06cc0aee3 197 Gene3D G3DSA:1.10.357.10 61 196 2.4E-40 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS05290 1f35d4cf79fefa3b55ebabd06cc0aee3 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS05290 1f35d4cf79fefa3b55ebabd06cc0aee3 197 Gene3D G3DSA:1.10.10.60 8 60 7.7E-25 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS05290 1f35d4cf79fefa3b55ebabd06cc0aee3 197 SUPERFAMILY SSF46689 5 88 4.19E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS05290 1f35d4cf79fefa3b55ebabd06cc0aee3 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.7E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05290 1f35d4cf79fefa3b55ebabd06cc0aee3 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.7E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05290 1f35d4cf79fefa3b55ebabd06cc0aee3 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.9E-23 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS05290 1f35d4cf79fefa3b55ebabd06cc0aee3 197 SUPERFAMILY SSF48498 84 196 1.34E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS19240 4c1ed00d9a3967611c46995c558f4af2 427 Pfam PF07690 Major Facilitator Superfamily 25 360 1.2E-43 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS19240 4c1ed00d9a3967611c46995c558f4af2 427 Gene3D G3DSA:1.20.1250.20 205 395 7.6E-8 T 06-07-2017 LK06_RS19240 4c1ed00d9a3967611c46995c558f4af2 427 SUPERFAMILY SSF103473 9 401 3.4E-58 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS19240 4c1ed00d9a3967611c46995c558f4af2 427 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 13 390 1.9E-73 T 06-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 LK06_RS19240 4c1ed00d9a3967611c46995c558f4af2 427 Gene3D G3DSA:1.20.1250.20 15 196 2.5E-27 T 06-07-2017 LK06_RS14030 43c2a237f8c0d270872d33d3a3328dcf 141 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 7 53 2.9E-5 T 06-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal LK06_RS14030 43c2a237f8c0d270872d33d3a3328dcf 141 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 5 108 3.3E-29 T 06-07-2017 IPR021202 Helicase/secretion neighbourhood TadE-like protein LK06_RS26950 5fbdae2829ae70f6fbb4e876b59ca76d 311 SUPERFAMILY SSF52402 16 219 5.82E-62 T 06-07-2017 LK06_RS26950 5fbdae2829ae70f6fbb4e876b59ca76d 311 Gene3D G3DSA:3.40.50.620 252 260 3.3E-51 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS26950 5fbdae2829ae70f6fbb4e876b59ca76d 311 Gene3D G3DSA:3.40.50.620 15 219 3.3E-51 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS26950 5fbdae2829ae70f6fbb4e876b59ca76d 311 PIRSF PIRSF002936 11 311 2.8E-136 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 LK06_RS26950 5fbdae2829ae70f6fbb4e876b59ca76d 311 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 20 311 1.4E-136 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 LK06_RS26950 5fbdae2829ae70f6fbb4e876b59ca76d 311 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 265 5.1E-47 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 LK06_RS27240 e12df82db661e5678dbff7ec9c7e68c0 286 Gene3D G3DSA:3.30.470.20 105 285 9.1E-29 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS27240 e12df82db661e5678dbff7ec9c7e68c0 286 Pfam PF13535 ATP-grasp domain 147 285 3.5E-16 T 06-07-2017 LK06_RS27240 e12df82db661e5678dbff7ec9c7e68c0 286 SUPERFAMILY SSF56059 104 285 2.47E-32 T 06-07-2017 LK06_RS27240 e12df82db661e5678dbff7ec9c7e68c0 286 SMART SM01209 111 284 2.1E-5 T 06-07-2017 LK06_RS18245 bd9bf45bb268873c20d081a62b64d03b 380 SUPERFAMILY SSF51338 5 51 1.57E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS18245 bd9bf45bb268873c20d081a62b64d03b 380 SUPERFAMILY SSF51338 345 375 1.57E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS18245 bd9bf45bb268873c20d081a62b64d03b 380 PIRSF PIRSF038994 5 377 9.9E-109 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 LK06_RS18245 bd9bf45bb268873c20d081a62b64d03b 380 SUPERFAMILY SSF51556 52 345 9.64E-90 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS18245 bd9bf45bb268873c20d081a62b64d03b 380 Pfam PF01979 Amidohydrolase family 49 374 1.6E-30 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS18245 bd9bf45bb268873c20d081a62b64d03b 380 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 1 371 3.2E-82 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 LK06_RS18245 bd9bf45bb268873c20d081a62b64d03b 380 Gene3D G3DSA:3.20.20.140 54 329 9.5E-96 T 06-07-2017 LK06_RS18245 bd9bf45bb268873c20d081a62b64d03b 380 Gene3D G3DSA:2.30.40.10 4 53 3.5E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS18245 bd9bf45bb268873c20d081a62b64d03b 380 Gene3D G3DSA:2.30.40.10 330 361 1.0E-9 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS08165 e920cd5b44887e275897de98ce965bf5 649 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 538 548 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site LK06_RS08165 e920cd5b44887e275897de98ce965bf5 649 Pfam PF09286 Pro-kumamolisin, activation domain 56 189 1.6E-30 T 06-07-2017 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 LK06_RS08165 e920cd5b44887e275897de98ce965bf5 649 SUPERFAMILY SSF52743 619 636 2.23E-49 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS08165 e920cd5b44887e275897de98ce965bf5 649 SUPERFAMILY SSF52743 244 591 2.23E-49 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS08165 e920cd5b44887e275897de98ce965bf5 649 SMART SM00944 51 190 5.2E-46 T 06-07-2017 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 LK06_RS08165 e920cd5b44887e275897de98ce965bf5 649 Pfam PF00082 Subtilase family 317 559 1.5E-13 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS08165 e920cd5b44887e275897de98ce965bf5 649 Gene3D G3DSA:3.40.50.200 238 636 4.5E-74 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS08165 e920cd5b44887e275897de98ce965bf5 649 SUPERFAMILY SSF54897 40 209 6.29E-40 T 06-07-2017 IPR009020 Proteinase propeptide inhibitor LK06_RS08290 b989d621f0521cac19f82584124b086c 378 Pfam PF09375 Imelysin 138 371 3.3E-43 T 06-07-2017 LK06_RS08290 b989d621f0521cac19f82584124b086c 378 Gene3D G3DSA:2.60.40.420 18 123 5.4E-8 T 06-07-2017 IPR008972 Cupredoxin LK06_RS08290 b989d621f0521cac19f82584124b086c 378 Pfam PF13473 Cupredoxin-like domain 15 115 4.8E-15 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain LK06_RS08290 b989d621f0521cac19f82584124b086c 378 SUPERFAMILY SSF49503 18 122 2.84E-5 T 06-07-2017 IPR008972 Cupredoxin LK06_RS08290 b989d621f0521cac19f82584124b086c 378 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 40 - T 06-07-2017 IPR010916 TonB box, conserved site LK06_RS26370 3bbb94b669cabc3510ec7df35d5781f6 659 SUPERFAMILY SSF51905 5 58 4.92E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26370 3bbb94b669cabc3510ec7df35d5781f6 659 SUPERFAMILY SSF51905 128 199 4.92E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26370 3bbb94b669cabc3510ec7df35d5781f6 659 SUPERFAMILY SSF51905 560 632 4.92E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26370 3bbb94b669cabc3510ec7df35d5781f6 659 Pfam PF13454 FAD-NAD(P)-binding 10 192 4.5E-43 T 06-07-2017 LK06_RS26370 3bbb94b669cabc3510ec7df35d5781f6 659 Gene3D G3DSA:3.50.50.60 9 199 6.6E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26370 3bbb94b669cabc3510ec7df35d5781f6 659 Gene3D G3DSA:3.50.50.60 572 609 6.6E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27155 b1fb90f842e1811a84c31a2e81745c8d 146 Gene3D G3DSA:3.30.530.20 4 142 1.4E-7 T 06-07-2017 IPR023393 START-like domain LK06_RS27155 b1fb90f842e1811a84c31a2e81745c8d 146 SUPERFAMILY SSF55961 4 142 3.74E-13 T 06-07-2017 LK06_RS16625 78988bce2e5b7cf10c5aa2a5c58603ba 515 Pfam PF00535 Glycosyl transferase family 2 27 192 7.7E-22 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS16625 78988bce2e5b7cf10c5aa2a5c58603ba 515 SUPERFAMILY SSF53448 10 236 5.91E-35 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS16625 78988bce2e5b7cf10c5aa2a5c58603ba 515 Pfam PF04138 GtrA-like protein 292 409 3.5E-11 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 LK06_RS16625 78988bce2e5b7cf10c5aa2a5c58603ba 515 Gene3D G3DSA:3.90.550.10 24 221 2.0E-20 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS17480 7fd109b5b0ac5ab33ee0b6f24bb26182 333 Gene3D G3DSA:1.10.530.10 49 191 2.5E-32 T 06-07-2017 LK06_RS17480 7fd109b5b0ac5ab33ee0b6f24bb26182 333 Pfam PF01464 Transglycosylase SLT domain 66 175 5.9E-16 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 LK06_RS17480 7fd109b5b0ac5ab33ee0b6f24bb26182 333 Gene3D G3DSA:3.90.1720.10 192 322 3.1E-39 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS17480 7fd109b5b0ac5ab33ee0b6f24bb26182 333 SUPERFAMILY SSF53955 48 188 2.58E-34 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS17480 7fd109b5b0ac5ab33ee0b6f24bb26182 333 Pfam PF00877 NlpC/P60 family 212 311 4.0E-24 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS17480 7fd109b5b0ac5ab33ee0b6f24bb26182 333 SUPERFAMILY SSF54001 191 321 1.08E-36 T 06-07-2017 LK06_RS11890 2b34d2576bc7b8be6e1d654d3742c2e8 1250 Pfam PF13641 Glycosyltransferase like family 2 44 289 6.0E-16 T 06-07-2017 LK06_RS11890 2b34d2576bc7b8be6e1d654d3742c2e8 1250 Gene3D G3DSA:3.90.550.10 31 111 1.8E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11890 2b34d2576bc7b8be6e1d654d3742c2e8 1250 Gene3D G3DSA:3.90.550.10 147 289 1.8E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11890 2b34d2576bc7b8be6e1d654d3742c2e8 1250 SUPERFAMILY SSF53448 146 293 5.94E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11890 2b34d2576bc7b8be6e1d654d3742c2e8 1250 SUPERFAMILY SSF53448 29 107 5.94E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS22020 bf89b786d92e20bc6fbf703428718ee1 232 SUPERFAMILY SSF53335 37 231 1.18E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS22020 bf89b786d92e20bc6fbf703428718ee1 232 Gene3D G3DSA:3.40.50.150 34 231 4.0E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS22020 bf89b786d92e20bc6fbf703428718ee1 232 Pfam PF01596 O-methyltransferase 57 229 1.4E-22 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 LK06_RS24070 2b39be2fb44d5fcd6ba032df95d2951c 531 SUPERFAMILY SSF52096 17 271 5.64E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS24070 2b39be2fb44d5fcd6ba032df95d2951c 531 Pfam PF01039 Carboxyl transferase domain 44 528 3.6E-199 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS24070 2b39be2fb44d5fcd6ba032df95d2951c 531 SUPERFAMILY SSF52096 269 531 1.46E-89 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS24070 2b39be2fb44d5fcd6ba032df95d2951c 531 Gene3D G3DSA:3.90.226.10 25 273 1.6E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS24070 2b39be2fb44d5fcd6ba032df95d2951c 531 Gene3D G3DSA:3.90.226.10 274 530 1.0E-102 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS15580 f30a2adbaee08a681a6604db10ebb04d 491 Gene3D G3DSA:3.90.1310.10 74 143 6.5E-6 T 06-07-2017 LK06_RS15580 f30a2adbaee08a681a6604db10ebb04d 491 Pfam PF00905 Penicillin binding protein transpeptidase domain 158 484 2.7E-66 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LK06_RS15580 f30a2adbaee08a681a6604db10ebb04d 491 Gene3D G3DSA:3.40.710.10 144 490 3.4E-91 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS15580 f30a2adbaee08a681a6604db10ebb04d 491 SUPERFAMILY SSF56601 112 490 4.44E-83 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS21160 e25e86f097c62f27bf60ee751d1a3fa4 250 Pfam PF01927 Mut7-C RNAse domain 90 231 1.2E-41 T 06-07-2017 IPR002782 Mut7-C RNAse domain LK06_RS21160 e25e86f097c62f27bf60ee751d1a3fa4 250 Pfam PF14451 Mut7-C ubiquitin 4 82 5.3E-25 T 06-07-2017 IPR027798 Ubiquitin Mut7-C domain LK06_RS11995 fcadc04dc4f53a730c1c65adef3d249a 168 SUPERFAMILY SSF160904 5 166 6.28E-38 T 06-07-2017 LK06_RS11995 fcadc04dc4f53a730c1c65adef3d249a 168 Pfam PF11706 CGNR zinc finger 124 166 8.0E-18 T 06-07-2017 IPR021005 Zinc finger, CGNR LK06_RS11995 fcadc04dc4f53a730c1c65adef3d249a 168 Gene3D G3DSA:1.10.3300.10 10 166 1.4E-37 T 06-07-2017 IPR023286 ABATE domain LK06_RS23490 9ed872e021c66bd67c5268b20e9cb3c9 435 SUPERFAMILY SSF103473 40 422 9.29E-32 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS23490 9ed872e021c66bd67c5268b20e9cb3c9 435 Pfam PF07690 Major Facilitator Superfamily 44 318 7.0E-12 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS23490 9ed872e021c66bd67c5268b20e9cb3c9 435 Gene3D G3DSA:1.20.1250.20 240 412 5.4E-9 T 06-07-2017 LK06_RS23490 9ed872e021c66bd67c5268b20e9cb3c9 435 Gene3D G3DSA:1.20.1250.20 40 223 3.5E-11 T 06-07-2017 LK06_RS09340 9dc4c4922da8c95ab7627d926813c9c1 67 Gene3D G3DSA:2.120.10.10 9 59 2.4E-5 T 06-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 LK06_RS12615 065401f2e24443bfd375ed0e72b253e3 88 Pfam PF04226 Transglycosylase associated protein 33 83 1.5E-8 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 LK06_RS30670 0fff34bc1bcf6eae41397a1bc17f91bf 536 SUPERFAMILY SSF53474 187 241 6.77E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30670 0fff34bc1bcf6eae41397a1bc17f91bf 536 SUPERFAMILY SSF53474 387 489 6.77E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30670 0fff34bc1bcf6eae41397a1bc17f91bf 536 SUPERFAMILY SSF53474 89 147 6.77E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30670 0fff34bc1bcf6eae41397a1bc17f91bf 536 Gene3D G3DSA:3.40.50.1820 381 504 1.7E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30670 0fff34bc1bcf6eae41397a1bc17f91bf 536 Gene3D G3DSA:3.40.50.1820 185 313 1.7E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30670 0fff34bc1bcf6eae41397a1bc17f91bf 536 Gene3D G3DSA:3.40.50.1820 64 146 1.7E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30670 0fff34bc1bcf6eae41397a1bc17f91bf 536 Pfam PF00561 alpha/beta hydrolase fold 98 481 3.6E-34 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS10545 054226d70ee85fc97f32c344eed24592 400 SUPERFAMILY SSF48452 174 282 6.07E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS10545 054226d70ee85fc97f32c344eed24592 400 SUPERFAMILY SSF47413 4 70 3.56E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10545 054226d70ee85fc97f32c344eed24592 400 Gene3D G3DSA:1.10.260.40 4 68 3.3E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10545 054226d70ee85fc97f32c344eed24592 400 Pfam PF13560 Helix-turn-helix domain 5 70 2.4E-6 T 06-07-2017 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 Pfam PF01266 FAD dependent oxidoreductase 38 391 8.5E-46 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 Gene3D G3DSA:3.50.50.60 35 276 1.5E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 352 358 1.3E-20 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 381 393 1.3E-20 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 112 124 1.3E-20 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 50 60 1.3E-20 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 37 49 1.3E-20 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 66 78 1.3E-20 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 423 538 6.8E-15 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 SUPERFAMILY SSF51905 145 256 2.36E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS05115 70a1f706e26730ca04154c746a1a3f1e 538 SUPERFAMILY SSF51905 25 103 2.36E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS00690 e7760456db50432a8c738539ad3173a2 197 Gene3D G3DSA:3.40.50.300 5 185 2.8E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00690 e7760456db50432a8c738539ad3173a2 197 SUPERFAMILY SSF52540 6 181 4.45E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00690 e7760456db50432a8c738539ad3173a2 197 PRINTS PR00449 Transforming protein P21 ras signature 156 178 2.9E-6 T 06-07-2017 LK06_RS00690 e7760456db50432a8c738539ad3173a2 197 PRINTS PR00449 Transforming protein P21 ras signature 9 30 2.9E-6 T 06-07-2017 LK06_RS00690 e7760456db50432a8c738539ad3173a2 197 Pfam PF03029 Conserved hypothetical ATP binding protein 13 178 1.4E-23 T 06-07-2017 IPR004130 GPN-loop GTPase LK06_RS21875 892c876af6f6c2e2b3bd125489c4ddae 589 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 120 503 4.8E-58 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS21875 892c876af6f6c2e2b3bd125489c4ddae 589 SUPERFAMILY SSF53850 71 587 1.9E-80 T 06-07-2017 LK06_RS21875 892c876af6f6c2e2b3bd125489c4ddae 589 PIRSF PIRSF002741 20 589 4.8E-54 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LK06_RS21875 892c876af6f6c2e2b3bd125489c4ddae 589 Gene3D G3DSA:3.40.190.10 241 356 4.4E-16 T 06-07-2017 LK06_RS21875 892c876af6f6c2e2b3bd125489c4ddae 589 Gene3D G3DSA:3.10.105.10 357 554 2.8E-34 T 06-07-2017 LK06_RS21875 892c876af6f6c2e2b3bd125489c4ddae 589 Gene3D G3DSA:3.90.76.10 83 240 9.1E-23 T 06-07-2017 LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 SUPERFAMILY SSF55785 204 324 1.48E-18 T 06-07-2017 IPR000014 PAS domain LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 Pfam PF00990 Diguanylate cyclase, GGDEF domain 421 543 8.6E-32 T 06-07-2017 IPR000160 GGDEF domain LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 SUPERFAMILY SSF55073 421 546 1.33E-35 T 06-07-2017 IPR029787 Nucleotide cyclase LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 SMART SM00267 328 550 1.0E-29 T 06-07-2017 IPR000160 GGDEF domain LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 SUPERFAMILY SSF55781 13 211 1.48E-14 T 06-07-2017 IPR029016 GAF domain-like LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 SMART SM00065 29 198 0.0013 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 Gene3D G3DSA:3.30.450.40 10 193 3.6E-15 T 06-07-2017 IPR029016 GAF domain-like LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 212 334 1.8E-14 T 06-07-2017 IPR000014 PAS domain LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 Pfam PF00989 PAS fold 237 315 2.3E-7 T 06-07-2017 IPR013767 PAS fold GO:0006355 LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 SMART SM00086 286 328 0.007 T 06-07-2017 IPR001610 PAC motif LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 Gene3D G3DSA:3.30.70.270 341 366 1.4E-46 T 06-07-2017 LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 Gene3D G3DSA:3.30.70.270 419 546 1.4E-46 T 06-07-2017 LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 Gene3D G3DSA:3.30.450.20 208 325 1.1E-19 T 06-07-2017 LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 SMART SM00091 216 286 2.0E-6 T 06-07-2017 IPR000014 PAS domain LK06_RS18230 18e011fe119ec11464eecdf691c638ca 551 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 420 543 2.0E-29 T 06-07-2017 IPR000160 GGDEF domain LK06_RS29890 81ba1c7f8fb1052a667439092e211fdd 188 Pfam PF17197 Domain of unknown function (DUF5134) 33 188 3.6E-37 T 06-07-2017 IPR033458 Protein of unknown function DUF5134 LK06_RS06870 b333d7c7fbf2a5402b65367e6e264f5b 643 Pfam PF13406 Transglycosylase SLT domain 181 224 2.0E-6 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 LK06_RS06870 b333d7c7fbf2a5402b65367e6e264f5b 643 SUPERFAMILY SSF53955 88 262 8.86E-35 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS06870 b333d7c7fbf2a5402b65367e6e264f5b 643 Gene3D G3DSA:1.10.530.10 119 146 8.1E-11 T 06-07-2017 LK06_RS06870 b333d7c7fbf2a5402b65367e6e264f5b 643 Gene3D G3DSA:1.10.530.10 182 246 8.1E-11 T 06-07-2017 LK06_RS23285 e6a891acd049c0237be170f3c548d56c 182 Pfam PF00430 ATP synthase B/B' CF(0) 25 153 6.8E-27 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 LK06_RS23285 e6a891acd049c0237be170f3c548d56c 182 SUPERFAMILY SSF81573 80 138 1.31E-10 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain LK06_RS23285 e6a891acd049c0237be170f3c548d56c 182 Gene3D G3DSA:1.20.5.620 80 139 1.3E-12 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain LK06_RS23285 e6a891acd049c0237be170f3c548d56c 182 Hamap MF_01398 ATP synthase subunit b [atpF]. 8 174 12.054 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 LK06_RS23285 e6a891acd049c0237be170f3c548d56c 182 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 28 174 2.6E-25 T 06-07-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 LK06_RS01560 b8ab31a308d90a30e63826593e5acaee 163 SUPERFAMILY SSF56784 8 146 4.03E-19 T 06-07-2017 IPR023214 HAD-like domain LK06_RS01560 b8ab31a308d90a30e63826593e5acaee 163 Gene3D G3DSA:3.40.50.1000 8 138 8.2E-17 T 06-07-2017 IPR023214 HAD-like domain LK06_RS21055 62c451295e435a1b34fd1c1c96fc2340 70 Pfam PF03621 MbtH-like protein 1 52 9.6E-28 T 06-07-2017 IPR005153 MbtH-like protein LK06_RS21055 62c451295e435a1b34fd1c1c96fc2340 70 SMART SM00923 3 53 4.2E-30 T 06-07-2017 IPR005153 MbtH-like protein LK06_RS21055 62c451295e435a1b34fd1c1c96fc2340 70 SUPERFAMILY SSF160582 1 68 2.35E-31 T 06-07-2017 LK06_RS21055 62c451295e435a1b34fd1c1c96fc2340 70 Gene3D G3DSA:3.90.820.10 10 69 2.9E-31 T 06-07-2017 LK06_RS15060 963bccf5f48f3d1edc5151cae29835e2 336 Pfam PF00899 ThiF family 76 213 1.7E-11 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 LK06_RS15060 963bccf5f48f3d1edc5151cae29835e2 336 Gene3D G3DSA:3.40.50.720 70 252 3.1E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15060 963bccf5f48f3d1edc5151cae29835e2 336 Gene3D G3DSA:3.40.50.720 284 314 3.1E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS15060 963bccf5f48f3d1edc5151cae29835e2 336 SUPERFAMILY SSF69572 60 228 7.06E-19 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 LK06_RS13950 0f063a8be46cbde7e75083f10d34df7a 338 Gene3D G3DSA:3.40.50.300 40 273 7.9E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13950 0f063a8be46cbde7e75083f10d34df7a 338 Pfam PF00005 ABC transporter 75 220 4.5E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS13950 0f063a8be46cbde7e75083f10d34df7a 338 ProSitePatterns PS00211 ABC transporters family signature. 193 207 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS13950 0f063a8be46cbde7e75083f10d34df7a 338 SMART SM00382 81 268 1.4E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS13950 0f063a8be46cbde7e75083f10d34df7a 338 SUPERFAMILY SSF52540 41 276 1.18E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20820 ec625ec084ada1cfeb9d9f040b76e206 145 Pfam PF13772 AIG2-like family 59 140 1.5E-21 T 06-07-2017 LK06_RS20820 ec625ec084ada1cfeb9d9f040b76e206 145 SUPERFAMILY SSF110857 1 119 1.7E-13 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like LK06_RS20820 ec625ec084ada1cfeb9d9f040b76e206 145 Gene3D G3DSA:3.10.490.10 1 145 4.5E-46 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like LK06_RS23720 cbb8bf80ed17ab4fba858a9875a50cb3 70 Gene3D G3DSA:1.10.238.10 5 69 1.4E-16 T 06-07-2017 IPR011992 EF-hand domain pair LK06_RS23720 cbb8bf80ed17ab4fba858a9875a50cb3 70 SUPERFAMILY SSF47473 4 68 2.51E-17 T 06-07-2017 IPR011992 EF-hand domain pair LK06_RS23720 cbb8bf80ed17ab4fba858a9875a50cb3 70 ProSitePatterns PS00018 EF-hand calcium-binding domain. 52 64 - T 06-07-2017 IPR018247 EF-Hand 1, calcium-binding site LK06_RS23720 cbb8bf80ed17ab4fba858a9875a50cb3 70 Pfam PF13499 EF-hand domain pair 6 65 1.3E-10 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 LK06_RS23720 cbb8bf80ed17ab4fba858a9875a50cb3 70 ProSitePatterns PS00018 EF-hand calcium-binding domain. 15 27 - T 06-07-2017 IPR018247 EF-Hand 1, calcium-binding site LK06_RS23720 cbb8bf80ed17ab4fba858a9875a50cb3 70 SMART SM00054 6 34 0.008 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 SUPERFAMILY SSF55909 1 402 6.87E-121 T 06-07-2017 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 Pfam PF02274 Amidinotransferase 18 400 6.3E-87 T 06-07-2017 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 PIRSF PIRSF006356 1 403 4.7E-137 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 Hamap MF_00242 Arginine deiminase [arcA]. 1 403 43.086 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 PRINTS PR01466 Bacterial arginine deiminase signature 339 356 7.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 PRINTS PR01466 Bacterial arginine deiminase signature 178 193 7.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 PRINTS PR01466 Bacterial arginine deiminase signature 150 168 7.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 PRINTS PR01466 Bacterial arginine deiminase signature 359 373 7.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 PRINTS PR01466 Bacterial arginine deiminase signature 382 400 7.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 PRINTS PR01466 Bacterial arginine deiminase signature 2 22 7.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 Gene3D G3DSA:3.75.10.10 150 402 5.7E-121 T 06-07-2017 LK06_RS29325 916c3ad444dfc51e4dcf0778523792ad 404 Gene3D G3DSA:3.75.10.10 1 67 5.7E-121 T 06-07-2017 LK06_RS07360 0c4f254037d06a9354fc19d50f703085 795 Gene3D G3DSA:3.90.260.10 413 562 6.7E-22 T 06-07-2017 IPR002931 Transglutaminase-like LK06_RS07360 0c4f254037d06a9354fc19d50f703085 795 SUPERFAMILY SSF54001 413 553 1.16E-31 T 06-07-2017 LK06_RS07360 0c4f254037d06a9354fc19d50f703085 795 Pfam PF13559 Domain of unknown function (DUF4129) 669 738 7.6E-8 T 06-07-2017 IPR025403 Domain of unknown function DUF4129 LK06_RS07360 0c4f254037d06a9354fc19d50f703085 795 SMART SM00460 478 548 4.4E-21 T 06-07-2017 IPR002931 Transglutaminase-like LK06_RS07360 0c4f254037d06a9354fc19d50f703085 795 Pfam PF01841 Transglutaminase-like superfamily 432 546 7.7E-25 T 06-07-2017 IPR002931 Transglutaminase-like LK06_RS32365 ceacf03ed69343d6b1e4ac8fccebbcea 1761 Gene3D G3DSA:1.25.10.10 1151 1183 1.6E-6 T 06-07-2017 IPR011989 Armadillo-like helical LK06_RS32365 ceacf03ed69343d6b1e4ac8fccebbcea 1761 Gene3D G3DSA:1.25.10.10 849 941 1.6E-6 T 06-07-2017 IPR011989 Armadillo-like helical LK06_RS32365 ceacf03ed69343d6b1e4ac8fccebbcea 1761 Gene3D G3DSA:1.25.10.10 983 1004 1.6E-6 T 06-07-2017 IPR011989 Armadillo-like helical LK06_RS32365 ceacf03ed69343d6b1e4ac8fccebbcea 1761 SUPERFAMILY SSF48371 846 974 3.3E-7 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS32365 ceacf03ed69343d6b1e4ac8fccebbcea 1761 SUPERFAMILY SSF48371 1270 1340 3.3E-7 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS32365 ceacf03ed69343d6b1e4ac8fccebbcea 1761 SUPERFAMILY SSF48371 1146 1184 3.3E-7 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS32365 ceacf03ed69343d6b1e4ac8fccebbcea 1761 Gene3D G3DSA:3.40.50.300 344 437 9.8E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32365 ceacf03ed69343d6b1e4ac8fccebbcea 1761 SUPERFAMILY SSF52540 324 483 4.19E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32365 ceacf03ed69343d6b1e4ac8fccebbcea 1761 Pfam PF05729 NACHT domain 348 511 6.4E-10 T 06-07-2017 LK06_RS28175 2a384d1d651e1a904243cb4e680c6755 275 SUPERFAMILY SSF47413 20 76 2.36E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS28175 2a384d1d651e1a904243cb4e680c6755 275 SMART SM00530 22 77 4.2E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS28175 2a384d1d651e1a904243cb4e680c6755 275 Pfam PF13560 Helix-turn-helix domain 20 80 2.7E-12 T 06-07-2017 LK06_RS28175 2a384d1d651e1a904243cb4e680c6755 275 Gene3D G3DSA:1.10.260.40 23 76 7.6E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS24465 f0e9877ceb61e1e66a23c128eeb6c642 131 Pfam PF02021 Uncharacterised protein family UPF0102 22 114 6.0E-27 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 LK06_RS24465 f0e9877ceb61e1e66a23c128eeb6c642 131 Hamap MF_00048 UPF0102 protein YraN [yraN]. 15 127 21.228 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 LK06_RS24465 f0e9877ceb61e1e66a23c128eeb6c642 131 Gene3D G3DSA:3.40.1350.10 21 130 2.4E-35 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 LK06_RS24465 f0e9877ceb61e1e66a23c128eeb6c642 131 SUPERFAMILY SSF52980 20 115 1.72E-18 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LK06_RS12155 f5251ef3d343b3d29a4c14028b6b89df 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 1.5E-61 T 06-07-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS12155 f5251ef3d343b3d29a4c14028b6b89df 147 Pfam PF00572 Ribosomal protein L13 14 137 9.8E-58 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 LK06_RS12155 f5251ef3d343b3d29a4c14028b6b89df 147 PIRSF PIRSF002181 2 147 8.9E-49 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 LK06_RS12155 f5251ef3d343b3d29a4c14028b6b89df 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 06-07-2017 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 LK06_RS12155 f5251ef3d343b3d29a4c14028b6b89df 147 SUPERFAMILY SSF52161 4 144 1.3E-60 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 LK06_RS12155 f5251ef3d343b3d29a4c14028b6b89df 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 28.566 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 LK06_RS12155 f5251ef3d343b3d29a4c14028b6b89df 147 Gene3D G3DSA:3.90.1180.10 3 141 3.8E-64 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 LK06_RS29450 da07abd1d30687aa0894f9e1fa48d9ef 359 Gene3D G3DSA:1.10.600.10 14 358 7.0E-86 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS29450 da07abd1d30687aa0894f9e1fa48d9ef 359 Pfam PF00348 Polyprenyl synthetase 47 300 1.4E-56 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS29450 da07abd1d30687aa0894f9e1fa48d9ef 359 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 94 108 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS29450 da07abd1d30687aa0894f9e1fa48d9ef 359 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 237 249 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 LK06_RS29450 da07abd1d30687aa0894f9e1fa48d9ef 359 SUPERFAMILY SSF48576 15 358 8.63E-78 T 06-07-2017 IPR008949 Isoprenoid synthase domain LK06_RS16775 4979201ee2f6cb86622e17c4b2e6cf56 152 Pfam PF03479 Domain of unknown function (DUF296) 11 111 5.6E-9 T 06-07-2017 IPR005175 PPC domain LK06_RS16775 4979201ee2f6cb86622e17c4b2e6cf56 152 SUPERFAMILY SSF117856 1 142 2.88E-16 T 06-07-2017 LK06_RS16775 4979201ee2f6cb86622e17c4b2e6cf56 152 Gene3D G3DSA:3.30.1330.80 6 142 2.0E-18 T 06-07-2017 LK06_RS11230 c1b099750ab7c114d460294b5d50bfd0 478 Pfam PF00324 Amino acid permease 36 468 1.5E-108 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 LK06_RS11230 c1b099750ab7c114d460294b5d50bfd0 478 PIRSF PIRSF006060 7 473 7.5E-62 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS11230 c1b099750ab7c114d460294b5d50bfd0 478 ProSitePatterns PS00218 Amino acid permeases signature. 60 90 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 LK06_RS24910 d976c0728ecc9fa8b9708fe49ee760a6 249 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 22 241 4.4E-63 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 LK06_RS24910 d976c0728ecc9fa8b9708fe49ee760a6 249 SUPERFAMILY SSF69796 17 242 9.42E-52 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 LK06_RS24910 d976c0728ecc9fa8b9708fe49ee760a6 249 Pfam PF02511 Thymidylate synthase complementing protein 24 235 3.2E-50 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 LK06_RS24910 d976c0728ecc9fa8b9708fe49ee760a6 249 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 18 249 27.402 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 LK06_RS03935 4cfb944896228c298ce2a29b211f49b9 90 SUPERFAMILY SSF101386 5 90 9.72E-21 T 06-07-2017 LK06_RS03935 4cfb944896228c298ce2a29b211f49b9 90 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 3 90 19.413 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 LK06_RS03935 4cfb944896228c298ce2a29b211f49b9 90 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 7 90 2.2E-24 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 LK06_RS03935 4cfb944896228c298ce2a29b211f49b9 90 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 15 89 2.2E-10 T 06-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 LK06_RS10330 74f171faeed2664d706c642474e25e73 79 Pfam PF03777 Small secreted domain (DUF320) 23 78 2.5E-30 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 206 5.7E-16 T 06-07-2017 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.7E-15 T 06-07-2017 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 344 366 4.7E-15 T 06-07-2017 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 4.7E-15 T 06-07-2017 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 4.7E-15 T 06-07-2017 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 Gene3D G3DSA:3.40.50.720 134 184 1.3E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 SUPERFAMILY SSF51905 262 393 1.77E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 SUPERFAMILY SSF51905 68 203 1.77E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 SUPERFAMILY SSF51905 1 35 1.77E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 1.0E-12 T 06-07-2017 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 1.0E-12 T 06-07-2017 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.0E-12 T 06-07-2017 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 Gene3D G3DSA:3.50.50.60 1 133 1.5E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 Gene3D G3DSA:3.50.50.60 185 222 1.8E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10390 3520071c7f9bf636b8195caffa755813 418 Gene3D G3DSA:3.50.50.60 262 394 1.8E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS12635 637b8c26e8124e37f1e2890c6bf917e5 507 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 16 499 14.903 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 LK06_RS12635 637b8c26e8124e37f1e2890c6bf917e5 507 Pfam PF00361 Proton-conducting membrane transporter 143 448 1.9E-52 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS04245 329641537a2730916a6c4366f936767b 409 Gene3D G3DSA:1.20.120.20 316 406 5.3E-4 T 06-07-2017 LK06_RS04245 329641537a2730916a6c4366f936767b 409 Pfam PF03993 Domain of Unknown Function (DUF349) 91 164 4.0E-13 T 06-07-2017 IPR007139 Protein of unknown function DUF349 LK06_RS04245 329641537a2730916a6c4366f936767b 409 Pfam PF03993 Domain of Unknown Function (DUF349) 168 241 1.7E-21 T 06-07-2017 IPR007139 Protein of unknown function DUF349 LK06_RS04245 329641537a2730916a6c4366f936767b 409 Pfam PF03993 Domain of Unknown Function (DUF349) 245 318 4.0E-21 T 06-07-2017 IPR007139 Protein of unknown function DUF349 LK06_RS16180 c2f7e2ec68e6d7c92a423f9cc1d0b3c3 299 Gene3D G3DSA:3.20.20.30 20 295 2.9E-60 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS16180 c2f7e2ec68e6d7c92a423f9cc1d0b3c3 299 Pfam PF00296 Luciferase-like monooxygenase 15 203 1.7E-43 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS16180 c2f7e2ec68e6d7c92a423f9cc1d0b3c3 299 SUPERFAMILY SSF51679 5 295 3.53E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS21685 68cc4da414bc78eb2ce4b5c2ae3fb1ab 130 SUPERFAMILY SSF88723 5 114 1.79E-8 T 06-07-2017 IPR029060 PIN domain-like LK06_RS21685 68cc4da414bc78eb2ce4b5c2ae3fb1ab 130 Pfam PF01850 PIN domain 6 110 1.4E-5 T 06-07-2017 IPR002716 PIN domain LK06_RS16285 7e8b8325206641620ac962d7d3cc67a9 187 SUPERFAMILY SSF55729 10 179 5.41E-43 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS16285 7e8b8325206641620ac962d7d3cc67a9 187 Gene3D G3DSA:3.40.630.30 10 178 2.2E-46 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS16285 7e8b8325206641620ac962d7d3cc67a9 187 Pfam PF13302 Acetyltransferase (GNAT) domain 12 155 6.8E-19 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS07890 950a2da3b3537b129ad51d5f012a3395 110 SUPERFAMILY SSF54909 2 106 7.51E-43 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS07890 950a2da3b3537b129ad51d5f012a3395 110 Gene3D G3DSA:3.30.70.1090 2 107 3.1E-47 T 06-07-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 LK06_RS07890 950a2da3b3537b129ad51d5f012a3395 110 Pfam PF04673 Polyketide synthesis cyclase 2 105 4.8E-46 T 06-07-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 LK06_RS07890 950a2da3b3537b129ad51d5f012a3395 110 ProDom PD012644 CYCLASE POLYKETIDE II SYNTHESIS ORF SYNTHASE JADI BIOSYNTHESIS ANTIBIOTIC CYCLASE-LIKE 2 105 3.0E-51 T 06-07-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 LK06_RS19355 a1708c4d483e74b4d6d06de578d17bdb 501 Pfam PF02080 TrkA-C domain 414 469 2.3E-11 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS19355 a1708c4d483e74b4d6d06de578d17bdb 501 Gene3D G3DSA:3.30.70.1450 411 469 8.5E-9 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS19355 a1708c4d483e74b4d6d06de578d17bdb 501 Pfam PF00999 Sodium/hydrogen exchanger family 15 385 3.3E-49 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 LK06_RS19355 a1708c4d483e74b4d6d06de578d17bdb 501 SUPERFAMILY SSF116726 409 477 9.81E-12 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS07280 ecfbbc48c1694c9874470ccd478b246c 239 PIRSF PIRSF004848 1 239 1.8E-65 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 LK06_RS07280 ecfbbc48c1694c9874470ccd478b246c 239 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 7 235 2.3E-43 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 LK06_RS07280 ecfbbc48c1694c9874470ccd478b246c 239 Gene3D G3DSA:3.20.20.10 2 236 1.8E-77 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS07280 ecfbbc48c1694c9874470ccd478b246c 239 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 LK06_RS07280 ecfbbc48c1694c9874470ccd478b246c 239 SUPERFAMILY SSF51419 4 233 2.29E-60 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS07280 ecfbbc48c1694c9874470ccd478b246c 239 Pfam PF01168 Alanine racemase, N-terminal domain 26 236 2.3E-21 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS31455 3047d893a4e64051a14e2598ff5f6840 129 PRINTS PR00050 Cold shock protein signature 25 34 8.6E-7 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS31455 3047d893a4e64051a14e2598ff5f6840 129 PRINTS PR00050 Cold shock protein signature 4 19 8.6E-7 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS31455 3047d893a4e64051a14e2598ff5f6840 129 PRINTS PR00050 Cold shock protein signature 39 57 8.6E-7 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS31455 3047d893a4e64051a14e2598ff5f6840 129 SMART SM00357 3 66 2.7E-13 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 LK06_RS31455 3047d893a4e64051a14e2598ff5f6840 129 Gene3D G3DSA:2.40.50.140 1 66 2.0E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS31455 3047d893a4e64051a14e2598ff5f6840 129 SUPERFAMILY SSF50249 1 65 1.05E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS31455 3047d893a4e64051a14e2598ff5f6840 129 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 1.6E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LK06_RS14460 79cfe0f135d23dab09960c980d6c7abf 316 Pfam PF03773 Predicted permease 36 312 5.2E-45 T 06-07-2017 IPR005524 Predicted permease DUF318 LK06_RS20700 9f8d225f71122d6c8a2ea8ef509a34a4 114 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 87 1.2E-8 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 LK06_RS20700 9f8d225f71122d6c8a2ea8ef509a34a4 114 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 40 80 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 LK06_RS20700 9f8d225f71122d6c8a2ea8ef509a34a4 114 Gene3D G3DSA:3.40.140.10 2 113 4.0E-37 T 06-07-2017 LK06_RS20700 9f8d225f71122d6c8a2ea8ef509a34a4 114 SUPERFAMILY SSF53927 2 112 3.2E-35 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 LK06_RS32195 31e242545d6996b2776ac356379dcfe3 1394 SUPERFAMILY SSF52266 1150 1385 1.69E-10 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS32195 31e242545d6996b2776ac356379dcfe3 1394 Gene3D G3DSA:3.40.50.1110 1171 1385 1.5E-8 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS11075 f0e6ac0622403c384e521429b08f4bbd 769 Pfam PF12704 MacB-like periplasmic core domain 14 225 1.5E-6 T 06-07-2017 IPR025857 MacB-like periplasmic core domain LK06_RS11075 f0e6ac0622403c384e521429b08f4bbd 769 Pfam PF12704 MacB-like periplasmic core domain 424 606 1.8E-9 T 06-07-2017 IPR025857 MacB-like periplasmic core domain LK06_RS11075 f0e6ac0622403c384e521429b08f4bbd 769 Pfam PF02687 FtsX-like permease family 262 381 9.5E-13 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS11075 f0e6ac0622403c384e521429b08f4bbd 769 Pfam PF02687 FtsX-like permease family 641 758 1.1E-15 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS01785 42ad67f874cb379751c6bed1bb133fe7 139 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 2 119 6.9E-48 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 LK06_RS01785 42ad67f874cb379751c6bed1bb133fe7 139 Pfam PF02261 Aspartate decarboxylase 2 114 6.9E-51 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 LK06_RS01785 42ad67f874cb379751c6bed1bb133fe7 139 Gene3D G3DSA:2.40.40.20 2 117 9.5E-55 T 06-07-2017 LK06_RS01785 42ad67f874cb379751c6bed1bb133fe7 139 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 1.0E-44 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 LK06_RS01785 42ad67f874cb379751c6bed1bb133fe7 139 PIRSF PIRSF006246 1 134 1.1E-51 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 LK06_RS01785 42ad67f874cb379751c6bed1bb133fe7 139 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 129 72.242 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 LK06_RS01785 42ad67f874cb379751c6bed1bb133fe7 139 SUPERFAMILY SSF50692 2 115 1.41E-47 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain LK06_RS03360 5fc5e3b8d38d1244777daf18f63fd411 205 Gene3D G3DSA:1.10.10.10 59 143 1.4E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03360 5fc5e3b8d38d1244777daf18f63fd411 205 Pfam PF03551 Transcriptional regulator PadR-like family 70 136 7.1E-20 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal LK06_RS03360 5fc5e3b8d38d1244777daf18f63fd411 205 SUPERFAMILY SSF46785 56 149 2.01E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS09195 180154293539ee8f5176957600050c21 285 SUPERFAMILY SSF53800 48 275 3.6E-36 T 06-07-2017 LK06_RS09195 180154293539ee8f5176957600050c21 285 Pfam PF01903 CbiX 54 150 5.6E-20 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 LK06_RS09195 180154293539ee8f5176957600050c21 285 Pfam PF01903 CbiX 179 269 9.2E-10 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 LK06_RS09195 180154293539ee8f5176957600050c21 285 Gene3D G3DSA:3.40.50.1400 172 281 8.7E-20 T 06-07-2017 LK06_RS09195 180154293539ee8f5176957600050c21 285 Gene3D G3DSA:3.40.50.1400 48 160 1.1E-28 T 06-07-2017 LK06_RS17505 4c9ac3e833fefa1d5c875f5cc1ac85a8 358 SUPERFAMILY SSF161098 91 345 5.36E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS17505 4c9ac3e833fefa1d5c875f5cc1ac85a8 358 Gene3D G3DSA:1.10.3720.10 82 352 2.3E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS17505 4c9ac3e833fefa1d5c875f5cc1ac85a8 358 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 155 356 8.2E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS17505 4c9ac3e833fefa1d5c875f5cc1ac85a8 358 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 84 350 1.6E-87 T 06-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 LK06_RS06640 59c665dab13bef32122d14ec91f75ce8 341 Pfam PF03668 P-loop ATPase protein family 59 341 6.3E-111 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 LK06_RS06640 59c665dab13bef32122d14ec91f75ce8 341 PIRSF PIRSF005052 58 341 5.0E-111 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 LK06_RS06640 59c665dab13bef32122d14ec91f75ce8 341 SUPERFAMILY SSF52540 59 211 4.69E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS06640 59c665dab13bef32122d14ec91f75ce8 341 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 58 340 41.378 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 LK06_RS06640 59c665dab13bef32122d14ec91f75ce8 341 Gene3D G3DSA:3.40.50.300 54 212 1.9E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32135 2a77220ecb974879b363e021b3a90122 402 Gene3D G3DSA:3.30.470.20 109 283 4.2E-11 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 LK06_RS32135 2a77220ecb974879b363e021b3a90122 402 Pfam PF02655 ATP-grasp domain 111 218 1.2E-7 T 06-07-2017 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 LK06_RS32135 2a77220ecb974879b363e021b3a90122 402 SUPERFAMILY SSF56059 91 313 2.89E-23 T 06-07-2017 LK06_RS03215 63f62b53bb8844a7d655a7aba34aa353 400 Gene3D G3DSA:1.20.1440.110 9 116 3.1E-34 T 06-07-2017 LK06_RS03215 63f62b53bb8844a7d655a7aba34aa353 400 Gene3D G3DSA:3.40.50.1820 121 399 3.2E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS03215 63f62b53bb8844a7d655a7aba34aa353 400 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 48 252 2.1E-8 T 06-07-2017 IPR010520 UPF0255 family LK06_RS03215 63f62b53bb8844a7d655a7aba34aa353 400 SUPERFAMILY SSF53474 12 258 1.49E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS03215 63f62b53bb8844a7d655a7aba34aa353 400 SUPERFAMILY SSF53474 292 398 1.49E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08875 b63abb34cf4983c4403ce9cd5c876fd6 292 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 58 280 7.6E-22 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS08875 b63abb34cf4983c4403ce9cd5c876fd6 292 SUPERFAMILY SSF52266 221 290 5.16E-27 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS08875 b63abb34cf4983c4403ce9cd5c876fd6 292 SUPERFAMILY SSF52266 53 192 5.16E-27 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS08875 b63abb34cf4983c4403ce9cd5c876fd6 292 Gene3D G3DSA:3.40.50.1110 227 290 3.7E-24 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS08875 b63abb34cf4983c4403ce9cd5c876fd6 292 Gene3D G3DSA:3.40.50.1110 54 191 3.7E-24 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS17225 cf9102caad6756b0e61d172bb41c5ad4 1483 Gene3D G3DSA:1.25.10.10 1121 1404 1.9E-7 T 06-07-2017 IPR011989 Armadillo-like helical LK06_RS17225 cf9102caad6756b0e61d172bb41c5ad4 1483 SUPERFAMILY SSF48371 1206 1357 4.8E-7 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS17225 cf9102caad6756b0e61d172bb41c5ad4 1483 SUPERFAMILY SSF48371 856 911 4.8E-7 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS18795 c83a3e7946e2cf67d34d63c5d2d08f30 291 Gene3D G3DSA:1.20.140.10 162 277 2.8E-27 T 06-07-2017 LK06_RS18795 c83a3e7946e2cf67d34d63c5d2d08f30 291 Gene3D G3DSA:1.10.540.10 3 91 3.5E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18795 c83a3e7946e2cf67d34d63c5d2d08f30 291 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 92 3.4E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS18795 c83a3e7946e2cf67d34d63c5d2d08f30 291 SUPERFAMILY SSF47203 157 287 5.8E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS18795 c83a3e7946e2cf67d34d63c5d2d08f30 291 SUPERFAMILY SSF56645 2 91 1.57E-14 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS18795 c83a3e7946e2cf67d34d63c5d2d08f30 291 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 162 280 4.6E-23 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS16075 550a3f8c5e9d0ac7bfe337b9b03396ea 125 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 115 4.1E-31 T 06-07-2017 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV LK06_RS30760 5ee10524fd07b151ec7763d6ce4c938a 127 Gene3D G3DSA:3.10.450.50 5 122 8.6E-16 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS30760 5ee10524fd07b151ec7763d6ce4c938a 127 SUPERFAMILY SSF54427 9 121 4.12E-32 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS30760 5ee10524fd07b151ec7763d6ce4c938a 127 Pfam PF12680 SnoaL-like domain 13 115 2.0E-13 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain LK06_RS11830 1e8a1ccd75499e35aaa0c06442e36017 334 Pfam PF06271 RDD family 18 144 5.4E-17 T 06-07-2017 IPR010432 RDD LK06_RS22670 e7063fb99e5450dfa7e1e15b6e037496 225 Gene3D G3DSA:3.40.50.150 63 203 2.5E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS22670 e7063fb99e5450dfa7e1e15b6e037496 225 SUPERFAMILY SSF53335 10 192 5.25E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS22670 e7063fb99e5450dfa7e1e15b6e037496 225 Pfam PF01564 Spermine/spermidine synthase 62 188 9.2E-7 T 06-07-2017 LK06_RS05965 38e330196cffd06de1a9c25a4efc1098 452 Gene3D G3DSA:1.20.1250.20 44 225 2.1E-20 T 06-07-2017 LK06_RS05965 38e330196cffd06de1a9c25a4efc1098 452 Gene3D G3DSA:1.20.1250.20 263 442 1.5E-13 T 06-07-2017 LK06_RS05965 38e330196cffd06de1a9c25a4efc1098 452 Pfam PF07690 Major Facilitator Superfamily 64 373 5.9E-22 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS05965 38e330196cffd06de1a9c25a4efc1098 452 SUPERFAMILY SSF103473 33 442 4.32E-47 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS05965 38e330196cffd06de1a9c25a4efc1098 452 TIGRFAM TIGR00896 CynX: cyanate transporter 47 422 2.5E-138 T 06-07-2017 IPR004747 Cyanate transport system protein GO:0016021 LK06_RS20970 f914e6177c48c3048e5563ada37b5975 167 Gene3D G3DSA:1.10.10.10 102 148 7.5E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20970 f914e6177c48c3048e5563ada37b5975 167 Pfam PF04545 Sigma-70, region 4 102 148 2.5E-7 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS20970 f914e6177c48c3048e5563ada37b5975 167 SUPERFAMILY SSF88659 101 151 2.62E-8 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS32090 0feae904e240364be22ef8ea5a09e9b9 294 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 89 287 6.3E-58 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS32090 0feae904e240364be22ef8ea5a09e9b9 294 Gene3D G3DSA:3.90.850.10 85 287 7.7E-62 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS32090 0feae904e240364be22ef8ea5a09e9b9 294 SUPERFAMILY SSF56529 85 287 2.22E-58 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS30045 a91fa367e24544d2d347637f79220390 221 Gene3D G3DSA:3.90.79.10 60 143 2.7E-11 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS30045 a91fa367e24544d2d347637f79220390 221 SUPERFAMILY SSF55811 49 178 6.23E-12 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS30045 a91fa367e24544d2d347637f79220390 221 Pfam PF00293 NUDIX domain 62 182 9.1E-8 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS00695 c9af52668771d89cd4c163965ed75520 408 SUPERFAMILY SSF48264 10 399 6.81E-56 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS00695 c9af52668771d89cd4c163965ed75520 408 Gene3D G3DSA:1.10.630.10 3 399 2.9E-83 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS00695 c9af52668771d89cd4c163965ed75520 408 PRINTS PR00359 B-class P450 signature 335 344 3.6E-19 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS00695 c9af52668771d89cd4c163965ed75520 408 PRINTS PR00359 B-class P450 signature 288 315 3.6E-19 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS00695 c9af52668771d89cd4c163965ed75520 408 PRINTS PR00359 B-class P450 signature 141 157 3.6E-19 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS00695 c9af52668771d89cd4c163965ed75520 408 PRINTS PR00359 B-class P450 signature 192 214 3.6E-19 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS21075 c680fec167fccf07a401438295fd114f 322 Gene3D G3DSA:3.60.130.10 26 317 2.8E-58 T 06-07-2017 LK06_RS21075 c680fec167fccf07a401438295fd114f 322 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 25 313 1.4E-40 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 LK06_RS21075 c680fec167fccf07a401438295fd114f 322 SUPERFAMILY SSF51197 23 314 2.01E-68 T 06-07-2017 LK06_RS02595 ee7c1576229f9356c9e665a7885e7d6c 416 Gene3D G3DSA:1.20.1290.10 188 230 1.0E-17 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS02595 ee7c1576229f9356c9e665a7885e7d6c 416 Gene3D G3DSA:1.20.1290.10 67 155 1.0E-17 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS02595 ee7c1576229f9356c9e665a7885e7d6c 416 Pfam PF02627 Carboxymuconolactone decarboxylase family 109 154 1.2E-5 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS02595 ee7c1576229f9356c9e665a7885e7d6c 416 SUPERFAMILY SSF69118 66 231 3.52E-23 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS22805 b80917a0b6bc5d9c0cf01f5b886f67ca 118 Pfam PF12840 Helix-turn-helix domain 24 80 6.0E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22805 b80917a0b6bc5d9c0cf01f5b886f67ca 118 SUPERFAMILY SSF46785 15 109 8.0E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22805 b80917a0b6bc5d9c0cf01f5b886f67ca 118 SMART SM00418 24 104 1.8E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS22805 b80917a0b6bc5d9c0cf01f5b886f67ca 118 Gene3D G3DSA:1.10.10.10 21 110 4.3E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22805 b80917a0b6bc5d9c0cf01f5b886f67ca 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 26 41 4.1E-7 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS22805 b80917a0b6bc5d9c0cf01f5b886f67ca 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 4.1E-7 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS24585 ea6d15af11a51bf4d763f888ab064766 397 Gene3D G3DSA:3.40.190.10 187 339 5.9E-42 T 06-07-2017 LK06_RS24585 ea6d15af11a51bf4d763f888ab064766 397 SUPERFAMILY SSF53850 53 395 1.14E-59 T 06-07-2017 LK06_RS24585 ea6d15af11a51bf4d763f888ab064766 397 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 132 145 2.5E-12 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LK06_RS24585 ea6d15af11a51bf4d763f888ab064766 397 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 164 180 2.5E-12 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LK06_RS24585 ea6d15af11a51bf4d763f888ab064766 397 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 290 309 2.5E-12 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LK06_RS24585 ea6d15af11a51bf4d763f888ab064766 397 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 116 130 2.5E-12 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LK06_RS24585 ea6d15af11a51bf4d763f888ab064766 397 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 246 265 2.5E-12 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LK06_RS24585 ea6d15af11a51bf4d763f888ab064766 397 Gene3D G3DSA:3.40.190.10 55 186 1.6E-12 T 06-07-2017 LK06_RS24585 ea6d15af11a51bf4d763f888ab064766 397 Pfam PF13416 Bacterial extracellular solute-binding protein 79 344 1.4E-25 T 06-07-2017 LK06_RS08595 b6357a840363704fc8c87e3dd09658af 274 Pfam PF12822 Protein of unknown function (DUF3816) 77 246 1.7E-19 T 06-07-2017 IPR024529 ECF transporter, substrate-specific component GO:0005215 LK06_RS08595 b6357a840363704fc8c87e3dd09658af 274 PIRSF PIRSF037395 6 270 2.5E-117 T 06-07-2017 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 LK06_RS12445 239731934a5cc4ac7a5a38c7c9e55171 313 SUPERFAMILY SSF89392 131 279 9.81E-9 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX LK06_RS05775 8f86e21dcae8a1e53fe3fec0fe9eb0b9 115 Pfam PF02036 SCP-2 sterol transfer family 33 102 1.5E-4 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS05775 8f86e21dcae8a1e53fe3fec0fe9eb0b9 115 SUPERFAMILY SSF55718 10 115 3.77E-14 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS05775 8f86e21dcae8a1e53fe3fec0fe9eb0b9 115 Gene3D G3DSA:3.30.1050.10 15 115 2.5E-14 T 06-07-2017 IPR003033 SCP2 sterol-binding domain LK06_RS17860 a0bfa7561af2171531debebbc32dfcd8 160 SMART SM01058 2 112 1.2E-32 T 06-07-2017 IPR003711 CarD-like/TRCF domain LK06_RS17860 a0bfa7561af2171531debebbc32dfcd8 160 SUPERFAMILY SSF141259 2 65 3.66E-15 T 06-07-2017 IPR003711 CarD-like/TRCF domain LK06_RS17860 a0bfa7561af2171531debebbc32dfcd8 160 Pfam PF02559 CarD-like/TRCF domain 3 110 1.4E-15 T 06-07-2017 IPR003711 CarD-like/TRCF domain LK06_RS06350 c0d1cea6712362918edb25962bdb7c94 239 Pfam PF01323 DSBA-like thioredoxin domain 2 207 2.5E-40 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 LK06_RS06350 c0d1cea6712362918edb25962bdb7c94 239 Gene3D G3DSA:3.40.30.10 1 211 1.1E-45 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS06350 c0d1cea6712362918edb25962bdb7c94 239 SUPERFAMILY SSF52833 1 212 4.35E-42 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS02875 ca1b35755c72c8859eea99b1c357f377 399 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 20 384 5.6E-90 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LK06_RS02875 ca1b35755c72c8859eea99b1c357f377 399 SUPERFAMILY SSF53383 57 385 3.06E-79 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS02875 ca1b35755c72c8859eea99b1c357f377 399 PIRSF PIRSF001434 8 387 4.0E-115 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LK06_RS02875 ca1b35755c72c8859eea99b1c357f377 399 Gene3D G3DSA:3.90.1150.10 270 385 5.9E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS02875 ca1b35755c72c8859eea99b1c357f377 399 Gene3D G3DSA:3.40.640.10 19 269 4.5E-70 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS23815 49a87b7c36cfff8371834990ecc841e0 325 Pfam PF08279 HTH domain 5 57 4.7E-17 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 LK06_RS23815 49a87b7c36cfff8371834990ecc841e0 325 Gene3D G3DSA:1.10.10.10 3 60 1.8E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS23815 49a87b7c36cfff8371834990ecc841e0 325 PIRSF PIRSF016838 1 320 6.7E-19 T 06-07-2017 IPR028349 Protein PafC LK06_RS23815 49a87b7c36cfff8371834990ecc841e0 325 Pfam PF13280 WYL domain 141 312 1.4E-32 T 06-07-2017 IPR026881 WYL domain LK06_RS23815 49a87b7c36cfff8371834990ecc841e0 325 SUPERFAMILY SSF46785 3 57 2.63E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26655 6b8f7730eddeae37e4679fa967f5ac30 554 Pfam PF08386 TAP-like protein 424 523 5.8E-25 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal LK06_RS26655 6b8f7730eddeae37e4679fa967f5ac30 554 Gene3D G3DSA:3.40.50.1820 74 167 2.1E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS26655 6b8f7730eddeae37e4679fa967f5ac30 554 Gene3D G3DSA:3.40.50.1820 211 337 2.1E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS26655 6b8f7730eddeae37e4679fa967f5ac30 554 Gene3D G3DSA:3.40.50.1820 390 511 2.1E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS26655 6b8f7730eddeae37e4679fa967f5ac30 554 SUPERFAMILY SSF53474 447 491 4.09E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS26655 6b8f7730eddeae37e4679fa967f5ac30 554 SUPERFAMILY SSF53474 201 266 4.09E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS26655 6b8f7730eddeae37e4679fa967f5ac30 554 SUPERFAMILY SSF53474 113 162 4.09E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS10960 a5c616beb16fbaa4511b35a09c263983 274 PIRSF PIRSF039085 20 274 1.9E-98 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LK06_RS10960 a5c616beb16fbaa4511b35a09c263983 274 Gene3D G3DSA:3.40.50.300 23 271 1.1E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10960 a5c616beb16fbaa4511b35a09c263983 274 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS10960 a5c616beb16fbaa4511b35a09c263983 274 Pfam PF00005 ABC transporter 39 198 7.4E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS10960 a5c616beb16fbaa4511b35a09c263983 274 SMART SM00382 48 247 1.3E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS10960 a5c616beb16fbaa4511b35a09c263983 274 SUPERFAMILY SSF52540 23 269 7.66E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10960 a5c616beb16fbaa4511b35a09c263983 274 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 24 274 3.4E-116 T 06-07-2017 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein LK06_RS13045 9ca6094647ec163704a99495963a748d 174 SUPERFAMILY SSF55729 17 173 9.45E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS13045 9ca6094647ec163704a99495963a748d 174 Gene3D G3DSA:3.40.630.30 16 173 4.1E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS13045 9ca6094647ec163704a99495963a748d 174 Pfam PF00583 Acetyltransferase (GNAT) family 68 147 1.4E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS27605 4f9f11b757f322b8af5e49200cbe1a42 747 Pfam PF04434 SWIM zinc finger 465 487 5.8E-6 T 06-07-2017 IPR007527 Zinc finger, SWIM-type GO:0008270 LK06_RS22820 da4bf669c9fb2b6ea985add5e70369ae 246 SUPERFAMILY SSF144091 7 183 1.7E-26 T 06-07-2017 LK06_RS22820 da4bf669c9fb2b6ea985add5e70369ae 246 Gene3D G3DSA:1.20.1540.10 16 181 5.7E-18 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 LK06_RS22820 da4bf669c9fb2b6ea985add5e70369ae 246 Pfam PF01694 Rhomboid family 49 183 1.1E-23 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 LK06_RS03285 73fb20e69de07b687b55f889a44e74be 75 Gene3D G3DSA:3.90.820.10 17 72 7.1E-26 T 06-07-2017 LK06_RS03285 73fb20e69de07b687b55f889a44e74be 75 SUPERFAMILY SSF160582 7 72 4.05E-24 T 06-07-2017 LK06_RS03285 73fb20e69de07b687b55f889a44e74be 75 Pfam PF03621 MbtH-like protein 8 58 1.4E-22 T 06-07-2017 IPR005153 MbtH-like protein LK06_RS03285 73fb20e69de07b687b55f889a44e74be 75 SMART SM00923 9 59 7.6E-22 T 06-07-2017 IPR005153 MbtH-like protein LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 SMART SM00382 40 232 0.0048 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 Pfam PF08494 DEAD/H associated 686 895 3.7E-77 T 06-07-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 Pfam PF00270 DEAD/DEAH box helicase 28 211 1.7E-27 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 SUPERFAMILY SSF52540 36 213 3.23E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 SUPERFAMILY SSF52540 279 322 3.23E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 SUPERFAMILY SSF52540 353 431 3.23E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 SMART SM00490 310 422 2.7E-13 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 Pfam PF00271 Helicase conserved C-terminal domain 297 422 1.8E-11 T 06-07-2017 IPR001650 Helicase, C-terminal LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 Gene3D G3DSA:3.40.50.300 289 451 1.8E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 SMART SM00487 23 242 1.7E-38 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain LK06_RS25025 661b70c63ab5571300c52e3ca7b535d5 1693 Gene3D G3DSA:3.40.50.300 19 209 1.2E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04045 31f7ac4f20240611e866ff3551a93321 347 Gene3D G3DSA:3.40.50.1360 74 329 6.7E-70 T 06-07-2017 LK06_RS04045 31f7ac4f20240611e866ff3551a93321 347 Pfam PF04198 Putative sugar-binding domain 81 329 1.7E-68 T 06-07-2017 IPR007324 Sugar-binding domain, putative GO:0030246 LK06_RS04045 31f7ac4f20240611e866ff3551a93321 347 SUPERFAMILY SSF100950 84 329 1.41E-56 T 06-07-2017 LK06_RS27750 4df476b1666e6e77f0fa345f4bd88701 383 Gene3D G3DSA:3.90.1200.10 196 333 3.9E-6 T 06-07-2017 LK06_RS27750 4df476b1666e6e77f0fa345f4bd88701 383 Pfam PF01636 Phosphotransferase enzyme family 71 327 1.0E-5 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS05170 dc41c924c4a86c6e968729b16fdad5a5 748 Pfam PF14490 Helix-hairpin-helix containing domain 161 245 2.8E-9 T 06-07-2017 IPR029493 RecD helicase-like helix-hairpin-helix domain LK06_RS05170 dc41c924c4a86c6e968729b16fdad5a5 748 Gene3D G3DSA:3.40.50.300 478 606 1.3E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05170 dc41c924c4a86c6e968729b16fdad5a5 748 Gene3D G3DSA:3.40.50.300 654 724 1.3E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05170 dc41c924c4a86c6e968729b16fdad5a5 748 SUPERFAMILY SSF52540 474 535 5.31E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05170 dc41c924c4a86c6e968729b16fdad5a5 748 SUPERFAMILY SSF52540 576 720 5.31E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21825 e19d814b68a2a8a2ee86c4a908d98a85 602 SUPERFAMILY SSF53850 71 600 3.72E-83 T 06-07-2017 LK06_RS21825 e19d814b68a2a8a2ee86c4a908d98a85 602 Gene3D G3DSA:3.90.76.10 84 256 4.3E-25 T 06-07-2017 LK06_RS21825 e19d814b68a2a8a2ee86c4a908d98a85 602 PIRSF PIRSF002741 13 602 2.0E-52 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LK06_RS21825 e19d814b68a2a8a2ee86c4a908d98a85 602 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 120 514 4.1E-60 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain LK06_RS21825 e19d814b68a2a8a2ee86c4a908d98a85 602 Gene3D G3DSA:3.10.105.10 366 564 2.4E-38 T 06-07-2017 LK06_RS21825 e19d814b68a2a8a2ee86c4a908d98a85 602 Gene3D G3DSA:3.40.190.10 257 365 5.0E-19 T 06-07-2017 LK06_RS27260 885e2f7c1423420c30b75abbf1ad12e4 348 Gene3D G3DSA:3.90.1150.10 235 344 5.7E-30 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS27260 885e2f7c1423420c30b75abbf1ad12e4 348 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 209 218 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 LK06_RS27260 885e2f7c1423420c30b75abbf1ad12e4 348 Gene3D G3DSA:3.40.640.10 27 234 8.5E-44 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS27260 885e2f7c1423420c30b75abbf1ad12e4 348 Pfam PF00155 Aminotransferase class I and II 14 332 6.0E-44 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS27260 885e2f7c1423420c30b75abbf1ad12e4 348 SUPERFAMILY SSF53383 12 339 1.9E-70 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS24065 4fd4de5263d7577b4d5f62157819a1a0 204 Gene3D G3DSA:1.10.3630.10 25 89 5.6E-5 T 06-07-2017 LK06_RS24065 4fd4de5263d7577b4d5f62157819a1a0 204 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 4 193 3.2E-20 T 06-07-2017 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 LK06_RS03035 1509ca631dd82ea6ff5c6cc6f2e2efc4 264 Gene3D G3DSA:3.40.50.1820 1 258 8.5E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS03035 1509ca631dd82ea6ff5c6cc6f2e2efc4 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 3.2E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS03035 1509ca631dd82ea6ff5c6cc6f2e2efc4 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 3.2E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS03035 1509ca631dd82ea6ff5c6cc6f2e2efc4 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 205 219 3.2E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS03035 1509ca631dd82ea6ff5c6cc6f2e2efc4 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 3.2E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS03035 1509ca631dd82ea6ff5c6cc6f2e2efc4 264 SUPERFAMILY SSF53474 2 257 1.2E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS03035 1509ca631dd82ea6ff5c6cc6f2e2efc4 264 Pfam PF00561 alpha/beta hydrolase fold 25 138 1.3E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS02685 60812476866f6d28755c26411b42e193 340 SUPERFAMILY SSF51679 16 322 2.06E-37 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS02685 60812476866f6d28755c26411b42e193 340 Pfam PF00296 Luciferase-like monooxygenase 13 311 4.2E-30 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS02685 60812476866f6d28755c26411b42e193 340 Gene3D G3DSA:3.20.20.30 16 324 3.6E-40 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS24760 186510be01bc98b3c3c3a10823eeb209 98 Pfam PF04296 Protein of unknown function (DUF448) 13 88 2.5E-23 T 06-07-2017 IPR007393 Domain of unknown function DUF448 LK06_RS24760 186510be01bc98b3c3c3a10823eeb209 98 SUPERFAMILY SSF64376 9 92 1.44E-23 T 06-07-2017 IPR007393 Domain of unknown function DUF448 LK06_RS24760 186510be01bc98b3c3c3a10823eeb209 98 Gene3D G3DSA:3.30.1230.10 8 90 2.9E-25 T 06-07-2017 IPR007393 Domain of unknown function DUF448 LK06_RS05670 591a30b69422e49d82bd8dd1d99d4577 340 Pfam PF03747 ADP-ribosylglycohydrolase 13 319 1.7E-56 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 LK06_RS05670 591a30b69422e49d82bd8dd1d99d4577 340 SUPERFAMILY SSF101478 12 227 3.92E-59 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 LK06_RS05670 591a30b69422e49d82bd8dd1d99d4577 340 SUPERFAMILY SSF101478 260 335 3.92E-59 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 LK06_RS05980 1876524dfa19facad4d7a79e55f82ab3 255 PIRSF PIRSF000094 2 255 6.9E-86 T 06-07-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 LK06_RS05980 1876524dfa19facad4d7a79e55f82ab3 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 2.6E-67 T 06-07-2017 LK06_RS05980 1876524dfa19facad4d7a79e55f82ab3 255 SUPERFAMILY SSF51735 6 253 9.47E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS05980 1876524dfa19facad4d7a79e55f82ab3 255 Gene3D G3DSA:3.40.50.720 3 252 6.7E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS17325 16a7b300f4818c1bca588266e6b0d46b 431 Gene3D G3DSA:1.20.1250.20 219 394 2.0E-13 T 06-07-2017 LK06_RS17325 16a7b300f4818c1bca588266e6b0d46b 431 Gene3D G3DSA:1.20.1250.20 16 190 1.2E-23 T 06-07-2017 LK06_RS17325 16a7b300f4818c1bca588266e6b0d46b 431 Pfam PF07690 Major Facilitator Superfamily 17 365 3.3E-31 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS17325 16a7b300f4818c1bca588266e6b0d46b 431 SUPERFAMILY SSF103473 14 399 2.88E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS17260 8600f0eb2ffe7931653160559be7626b 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 1.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17260 8600f0eb2ffe7931653160559be7626b 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 1.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17260 8600f0eb2ffe7931653160559be7626b 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17260 8600f0eb2ffe7931653160559be7626b 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17260 8600f0eb2ffe7931653160559be7626b 176 Gene3D G3DSA:1.10.10.10 3 149 6.8E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17260 8600f0eb2ffe7931653160559be7626b 176 SMART SM00347 31 134 4.0E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS17260 8600f0eb2ffe7931653160559be7626b 176 SUPERFAMILY SSF46785 3 148 8.31E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17260 8600f0eb2ffe7931653160559be7626b 176 Pfam PF12802 MarR family 43 97 9.9E-14 T 06-07-2017 LK06_RS23580 eae3cdc53fc19a636be6269439affe50 474 Gene3D G3DSA:1.10.3860.10 19 417 2.0E-104 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 LK06_RS23580 eae3cdc53fc19a636be6269439affe50 474 PRINTS PR00173 Glutamate-aspartate symporter signature 339 358 7.4E-22 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 LK06_RS23580 eae3cdc53fc19a636be6269439affe50 474 PRINTS PR00173 Glutamate-aspartate symporter signature 88 113 7.4E-22 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 LK06_RS23580 eae3cdc53fc19a636be6269439affe50 474 PRINTS PR00173 Glutamate-aspartate symporter signature 203 222 7.4E-22 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 LK06_RS23580 eae3cdc53fc19a636be6269439affe50 474 PRINTS PR00173 Glutamate-aspartate symporter signature 21 41 7.4E-22 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 LK06_RS23580 eae3cdc53fc19a636be6269439affe50 474 PRINTS PR00173 Glutamate-aspartate symporter signature 304 330 7.4E-22 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 LK06_RS23580 eae3cdc53fc19a636be6269439affe50 474 SUPERFAMILY SSF118215 23 413 3.79E-103 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 LK06_RS23580 eae3cdc53fc19a636be6269439affe50 474 Pfam PF00375 Sodium:dicarboxylate symporter family 23 413 5.3E-100 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 LK06_RS25120 aaefd2eb536b6988bb63780ff661eb2c 223 SUPERFAMILY SSF53213 96 223 1.7E-7 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 LK06_RS24415 520d0e0a931ceb7629f384e7d1f21bc9 79 SUPERFAMILY SSF54814 16 62 3.27E-8 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 LK06_RS24415 520d0e0a931ceb7629f384e7d1f21bc9 79 Gene3D G3DSA:3.30.300.120 6 63 1.4E-5 T 06-07-2017 LK06_RS24415 520d0e0a931ceb7629f384e7d1f21bc9 79 Pfam PF13083 KH domain 3 65 3.9E-19 T 06-07-2017 LK06_RS24415 520d0e0a931ceb7629f384e7d1f21bc9 79 Hamap MF_00088 UPF0109 protein . 2 73 21.556 T 06-07-2017 IPR020627 Uncharacterised protein family UPF0109 LK06_RS25610 e6118a8ac4e46a6c9e558bbbdbb8d20f 699 Pfam PF13365 Trypsin-like peptidase domain 28 176 7.0E-11 T 06-07-2017 LK06_RS25610 e6118a8ac4e46a6c9e558bbbdbb8d20f 699 Gene3D G3DSA:2.40.10.10 19 94 6.5E-5 T 06-07-2017 LK06_RS25610 e6118a8ac4e46a6c9e558bbbdbb8d20f 699 SUPERFAMILY SSF50494 21 208 6.71E-19 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS05220 de62f1a298509608103374a763e0a3b5 104 SUPERFAMILY SSF143212 11 86 2.35E-18 T 06-07-2017 LK06_RS05220 de62f1a298509608103374a763e0a3b5 104 Pfam PF08962 Domain of unknown function (DUF1876) 13 88 2.6E-22 T 06-07-2017 IPR015057 Protein of unknown function DUF1876 LK06_RS05220 de62f1a298509608103374a763e0a3b5 104 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 12 86 3.0E-7 T 06-07-2017 IPR015057 Protein of unknown function DUF1876 LK06_RS09190 cbc7966bec3526e360c8c38ef2a1f2fc 427 Pfam PF13286 Phosphohydrolase-associated domain 331 422 1.6E-19 T 06-07-2017 IPR026875 Phosphohydrolase-associated domain LK06_RS09190 cbc7966bec3526e360c8c38ef2a1f2fc 427 SUPERFAMILY SSF109604 203 421 7.51E-58 T 06-07-2017 LK06_RS09190 cbc7966bec3526e360c8c38ef2a1f2fc 427 SUPERFAMILY SSF109604 24 172 7.51E-58 T 06-07-2017 LK06_RS09190 cbc7966bec3526e360c8c38ef2a1f2fc 427 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 30 424 1.1E-73 T 06-07-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 LK06_RS09190 cbc7966bec3526e360c8c38ef2a1f2fc 427 SMART SM00471 69 232 6.2E-12 T 06-07-2017 IPR003607 HD/PDEase domain LK06_RS09190 cbc7966bec3526e360c8c38ef2a1f2fc 427 Gene3D G3DSA:1.10.3210.10 16 218 3.0E-66 T 06-07-2017 IPR006674 HD domain LK06_RS09190 cbc7966bec3526e360c8c38ef2a1f2fc 427 Pfam PF01966 HD domain 73 221 6.9E-15 T 06-07-2017 IPR006674 HD domain LK06_RS09190 cbc7966bec3526e360c8c38ef2a1f2fc 427 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 6 424 30.744 T 06-07-2017 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 LK06_RS09190 cbc7966bec3526e360c8c38ef2a1f2fc 427 Gene3D G3DSA:1.10.3410.10 219 351 2.5E-19 T 06-07-2017 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain LK06_RS17975 d991fd57b2c7e0392ef12ea8265a0884 135 ProSitePatterns PS00893 Nudix box signature. 30 51 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS17975 d991fd57b2c7e0392ef12ea8265a0884 135 SUPERFAMILY SSF55811 2 118 1.21E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS17975 d991fd57b2c7e0392ef12ea8265a0884 135 PRINTS PR00502 NUDIX hydrolase family signature 25 39 1.9E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS17975 d991fd57b2c7e0392ef12ea8265a0884 135 PRINTS PR00502 NUDIX hydrolase family signature 39 54 1.9E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LK06_RS17975 d991fd57b2c7e0392ef12ea8265a0884 135 Pfam PF00293 NUDIX domain 2 108 3.4E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS17975 d991fd57b2c7e0392ef12ea8265a0884 135 Gene3D G3DSA:3.90.79.10 1 110 7.2E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS28505 b36cbef506cfa84021693a0569eb17ff 275 SUPERFAMILY SSF54518 127 262 2.3E-10 T 06-07-2017 IPR025659 Tubby C-terminal-like domain LK06_RS28505 b36cbef506cfa84021693a0569eb17ff 275 Pfam PF10708 Protein of unknown function (DUF2510) 9 41 5.1E-15 T 06-07-2017 IPR018929 Domain of unknown function DUF2510 LK06_RS28505 b36cbef506cfa84021693a0569eb17ff 275 Pfam PF03803 Scramblase 80 265 1.2E-18 T 06-07-2017 IPR005552 Scramblase LK06_RS09760 387ad97fd95e4a1221fb182a12772360 469 SUPERFAMILY SSF52540 192 440 1.49E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09760 387ad97fd95e4a1221fb182a12772360 469 Pfam PF01580 FtsK/SpoIIIE family 206 385 3.3E-17 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS09760 387ad97fd95e4a1221fb182a12772360 469 Gene3D G3DSA:3.40.50.300 168 394 1.2E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24110 c33e8b71ff2a98c11a90c8f3ec2cba65 137 SUPERFAMILY SSF103196 2 125 3.92E-32 T 06-07-2017 LK06_RS24110 c33e8b71ff2a98c11a90c8f3ec2cba65 137 SMART SM00960 9 99 1.3E-32 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS24110 c33e8b71ff2a98c11a90c8f3ec2cba65 137 Gene3D G3DSA:3.30.450.30 3 123 1.7E-25 T 06-07-2017 LK06_RS24110 c33e8b71ff2a98c11a90c8f3ec2cba65 137 Pfam PF03259 Roadblock/LC7 domain 9 99 4.5E-26 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain LK06_RS13760 a5d6dc80a346a8a24a30b12b9bc9ec0e 375 SUPERFAMILY SSF53474 114 372 1.04E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS13760 a5d6dc80a346a8a24a30b12b9bc9ec0e 375 Pfam PF00756 Putative esterase 134 365 2.7E-17 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 LK06_RS13760 a5d6dc80a346a8a24a30b12b9bc9ec0e 375 Gene3D G3DSA:3.40.50.1820 112 372 6.9E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS24675 e5fc96b1ae0f8534926d9dbf540070fc 548 Pfam PF07905 Purine catabolism regulatory protein-like family 9 126 1.1E-31 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain LK06_RS24675 e5fc96b1ae0f8534926d9dbf540070fc 548 Pfam PF13556 PucR C-terminal helix-turn-helix domain 486 544 2.4E-22 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS15095 7b296c07336b81165514e48f32fb10ec 219 Pfam PF00005 ABC transporter 29 156 3.4E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS15095 7b296c07336b81165514e48f32fb10ec 219 Gene3D G3DSA:3.40.50.300 10 206 6.4E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15095 7b296c07336b81165514e48f32fb10ec 219 SMART SM00382 37 204 4.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS15095 7b296c07336b81165514e48f32fb10ec 219 SUPERFAMILY SSF52540 10 207 1.04E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01285 64d31533b80507a32ed6f95bf019749e 149 SUPERFAMILY SSF56235 1 119 3.4E-24 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS01285 64d31533b80507a32ed6f95bf019749e 149 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 22 117 5.3E-9 T 06-07-2017 IPR029132 Choloylglycine hydrolase/NAAA C-terminal LK06_RS01285 64d31533b80507a32ed6f95bf019749e 149 Gene3D G3DSA:3.60.60.10 1 136 3.1E-27 T 06-07-2017 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 Reactome: R-HSA-1660662 LK06_RS32315 39f421eda3364ffcb17f3f02f1184604 353 Pfam PF04909 Amidohydrolase 48 334 3.4E-36 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS32315 39f421eda3364ffcb17f3f02f1184604 353 Gene3D G3DSA:3.20.20.140 6 337 2.1E-81 T 06-07-2017 LK06_RS32315 39f421eda3364ffcb17f3f02f1184604 353 SUPERFAMILY SSF51556 41 338 9.53E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS04640 1221022859891b78a14d57e4620c3014 323 Gene3D G3DSA:3.20.20.100 48 313 2.1E-33 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS04640 1221022859891b78a14d57e4620c3014 323 SUPERFAMILY SSF51430 49 310 1.57E-36 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS04640 1221022859891b78a14d57e4620c3014 323 Pfam PF00248 Aldo/keto reductase family 51 307 1.9E-24 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS29960 7250f00b6ff1d039a32dfd7fb337a4f0 432 SUPERFAMILY SSF51621 100 345 1.26E-14 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS29960 7250f00b6ff1d039a32dfd7fb337a4f0 432 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 187 300 3.0E-7 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 LK06_RS29960 7250f00b6ff1d039a32dfd7fb337a4f0 432 Gene3D G3DSA:3.20.20.60 110 304 2.7E-14 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS19105 9049f0113e9f3826b7992d5e2cdea5c6 272 Pfam PF09359 VTC domain 33 118 1.8E-6 T 06-07-2017 IPR018966 VTC domain LK06_RS01145 80d18b87eb9814e1647fe04edac77adc 281 Pfam PF03537 Glycoside-hydrolase family GH114 57 259 3.3E-49 T 06-07-2017 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain LK06_RS01145 80d18b87eb9814e1647fe04edac77adc 281 SUPERFAMILY SSF51445 57 252 1.68E-22 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS25090 47da6e54ca5cbe55ed6c715875e8a63d 332 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 13 330 4.3E-70 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family LK06_RS25090 47da6e54ca5cbe55ed6c715875e8a63d 332 Gene3D G3DSA:3.40.190.10 125 263 8.7E-27 T 06-07-2017 LK06_RS25090 47da6e54ca5cbe55ed6c715875e8a63d 332 Pfam PF16868 NMT1-like family 46 328 6.1E-42 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family LK06_RS25090 47da6e54ca5cbe55ed6c715875e8a63d 332 SUPERFAMILY SSF53850 40 328 1.6E-54 T 06-07-2017 LK06_RS25090 47da6e54ca5cbe55ed6c715875e8a63d 332 Gene3D G3DSA:3.40.190.10 264 328 2.7E-25 T 06-07-2017 LK06_RS25090 47da6e54ca5cbe55ed6c715875e8a63d 332 Gene3D G3DSA:3.40.190.10 42 121 2.7E-25 T 06-07-2017 LK06_RS29850 c91204c6f6fe82aa11e7df89a7d35706 563 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 199 211 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS29850 c91204c6f6fe82aa11e7df89a7d35706 563 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 197 292 1.4E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS29850 c91204c6f6fe82aa11e7df89a7d35706 563 Gene3D G3DSA:2.40.110.10 197 295 1.1E-22 T 06-07-2017 LK06_RS29850 c91204c6f6fe82aa11e7df89a7d35706 563 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 417 436 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LK06_RS29850 c91204c6f6fe82aa11e7df89a7d35706 563 Gene3D G3DSA:1.20.140.10 296 463 4.5E-39 T 06-07-2017 LK06_RS29850 c91204c6f6fe82aa11e7df89a7d35706 563 SUPERFAMILY SSF56645 73 311 6.28E-38 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS29850 c91204c6f6fe82aa11e7df89a7d35706 563 SUPERFAMILY SSF47203 306 461 1.93E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS29850 c91204c6f6fe82aa11e7df89a7d35706 563 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 302 458 3.2E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS12555 b47b248541509523e49ad47e3da77e22 414 Pfam PF07690 Major Facilitator Superfamily 15 319 2.2E-17 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS12555 b47b248541509523e49ad47e3da77e22 414 SUPERFAMILY SSF103473 9 395 1.26E-27 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS12555 b47b248541509523e49ad47e3da77e22 414 Gene3D G3DSA:1.20.1250.20 221 392 6.1E-12 T 06-07-2017 LK06_RS12555 b47b248541509523e49ad47e3da77e22 414 Gene3D G3DSA:1.20.1250.20 9 192 8.6E-6 T 06-07-2017 LK06_RS01015 a37be1fb81b6b87c7aedfd96e322d837 588 SUPERFAMILY SSF52540 330 562 2.55E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01015 a37be1fb81b6b87c7aedfd96e322d837 588 SUPERFAMILY SSF90123 28 325 3.92E-42 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS01015 a37be1fb81b6b87c7aedfd96e322d837 588 SMART SM00382 363 547 1.0E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS01015 a37be1fb81b6b87c7aedfd96e322d837 588 Gene3D G3DSA:3.40.50.300 339 563 6.6E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01015 a37be1fb81b6b87c7aedfd96e322d837 588 Pfam PF00005 ABC transporter 354 500 8.8E-17 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS01015 a37be1fb81b6b87c7aedfd96e322d837 588 Gene3D G3DSA:1.20.1560.10 28 325 1.4E-39 T 06-07-2017 LK06_RS01015 a37be1fb81b6b87c7aedfd96e322d837 588 Pfam PF00664 ABC transporter transmembrane region 35 289 2.6E-19 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 LK06_RS32165 40f5a50cad9471b5fc1a35a2ebc59c79 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 1.1E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS32165 40f5a50cad9471b5fc1a35a2ebc59c79 356 Pfam PF01609 Transposase DDE domain 96 324 8.6E-21 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS09990 3f18584a8680a82e2c146eca3a4c3984 460 PIRSF PIRSF006060 3 459 6.4E-69 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS09990 3f18584a8680a82e2c146eca3a4c3984 460 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 LK06_RS09990 3f18584a8680a82e2c146eca3a4c3984 460 Pfam PF00324 Amino acid permease 26 433 2.7E-100 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 LK06_RS25880 8e6ce0de3f132a4216624f20ebac0249 424 Gene3D G3DSA:3.40.50.2000 199 369 3.2E-28 T 06-07-2017 LK06_RS25880 8e6ce0de3f132a4216624f20ebac0249 424 SUPERFAMILY SSF53756 1 391 3.77E-66 T 06-07-2017 LK06_RS25880 8e6ce0de3f132a4216624f20ebac0249 424 Pfam PF13439 Glycosyltransferase Family 4 19 203 6.6E-16 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LK06_RS25880 8e6ce0de3f132a4216624f20ebac0249 424 Pfam PF00534 Glycosyl transferases group 1 215 369 3.7E-26 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 LK06_RS28595 0da90422ab23dbf9145892104ebfb40a 247 Pfam PF04493 Endonuclease V 40 217 9.9E-63 T 06-07-2017 IPR007581 Endonuclease V GO:0004519|GO:0006281 LK06_RS28595 0da90422ab23dbf9145892104ebfb40a 247 Hamap MF_00801 Endonuclease V [nfi]. 13 227 32.855 T 06-07-2017 IPR007581 Endonuclease V GO:0004519|GO:0006281 LK06_RS11100 9849f857ba159202cc948e89c6db6df7 449 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 226 420 5.0E-24 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS11100 9849f857ba159202cc948e89c6db6df7 449 SUPERFAMILY SSF52266 221 432 2.6E-46 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS11100 9849f857ba159202cc948e89c6db6df7 449 Gene3D G3DSA:3.40.50.1110 223 435 9.7E-33 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS05285 3089ed0c09999b2ccd5a433fd3b62089 407 Gene3D G3DSA:2.40.110.10 133 241 2.2E-37 T 06-07-2017 LK06_RS05285 3089ed0c09999b2ccd5a433fd3b62089 407 Gene3D G3DSA:1.10.540.10 1 132 4.8E-34 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS05285 3089ed0c09999b2ccd5a433fd3b62089 407 SUPERFAMILY SSF47203 250 405 4.99E-41 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS05285 3089ed0c09999b2ccd5a433fd3b62089 407 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 239 2.2E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 LK06_RS05285 3089ed0c09999b2ccd5a433fd3b62089 407 Gene3D G3DSA:1.20.140.10 242 406 1.2E-44 T 06-07-2017 LK06_RS05285 3089ed0c09999b2ccd5a433fd3b62089 407 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 130 4.1E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 LK06_RS05285 3089ed0c09999b2ccd5a433fd3b62089 407 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 252 402 3.2E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LK06_RS05285 3089ed0c09999b2ccd5a433fd3b62089 407 SUPERFAMILY SSF56645 1 265 4.84E-61 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 LK06_RS16445 fc7885eaf89288fbf234774ef6b1003c 380 Gene3D G3DSA:1.10.443.10 177 357 5.1E-29 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS16445 fc7885eaf89288fbf234774ef6b1003c 380 Pfam PF00589 Phage integrase family 178 348 2.4E-16 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS16445 fc7885eaf89288fbf234774ef6b1003c 380 SUPERFAMILY SSF56349 71 350 1.56E-49 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS16445 fc7885eaf89288fbf234774ef6b1003c 380 Gene3D G3DSA:1.10.150.130 71 170 2.2E-15 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS16445 fc7885eaf89288fbf234774ef6b1003c 380 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 71 124 4.9E-9 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS25995 4debc7383e49042f7c819b4be7a435bd 605 Pfam PF01642 Methylmalonyl-CoA mutase 53 526 2.7E-126 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS25995 4debc7383e49042f7c819b4be7a435bd 605 Gene3D G3DSA:3.40.50.280 485 604 8.1E-44 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LK06_RS25995 4debc7383e49042f7c819b4be7a435bd 605 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 359 384 - T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS25995 4debc7383e49042f7c819b4be7a435bd 605 SUPERFAMILY SSF51703 10 522 2.94E-148 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS25995 4debc7383e49042f7c819b4be7a435bd 605 Gene3D G3DSA:1.10.196.20 8 41 9.2E-16 T 06-07-2017 IPR024067 Methylmalonyl-CoA mutase small subunit, N-terminal KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 LK06_RS25995 4debc7383e49042f7c819b4be7a435bd 605 Gene3D G3DSA:3.20.20.240 52 483 6.5E-130 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS16275 87cfc409af4468fccabb402fd056f8bf 148 SUPERFAMILY SSF55874 31 133 2.36E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16275 87cfc409af4468fccabb402fd056f8bf 148 Gene3D G3DSA:3.30.565.10 31 135 6.1E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16275 87cfc409af4468fccabb402fd056f8bf 148 Pfam PF13581 Histidine kinase-like ATPase domain 13 133 1.8E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS07125 1f1a454f79de3b1a66d69e444979202f 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 251 47.788 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 LK06_RS07125 1f1a454f79de3b1a66d69e444979202f 251 Gene3D G3DSA:3.20.20.70 6 251 1.3E-102 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS07125 1f1a454f79de3b1a66d69e444979202f 251 SUPERFAMILY SSF51366 3 251 4.4E-84 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 LK06_RS07125 1f1a454f79de3b1a66d69e444979202f 251 Pfam PF00977 Histidine biosynthesis protein 6 234 1.8E-87 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 LK06_RS07125 1f1a454f79de3b1a66d69e444979202f 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 251 2.7E-108 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 LK06_RS11010 fcc164334b389eb4e89e05512c3d2375 218 Gene3D G3DSA:3.40.50.1000 42 214 2.3E-28 T 06-07-2017 IPR023214 HAD-like domain LK06_RS11010 fcc164334b389eb4e89e05512c3d2375 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 37 182 8.3E-9 T 06-07-2017 IPR023214 HAD-like domain LK06_RS11010 fcc164334b389eb4e89e05512c3d2375 218 SUPERFAMILY SSF56784 1 214 9.34E-31 T 06-07-2017 IPR023214 HAD-like domain LK06_RS16210 dcad38acdf725210a745d4a4582b34f8 303 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS16210 dcad38acdf725210a745d4a4582b34f8 303 SMART SM00382 27 204 2.4E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS16210 dcad38acdf725210a745d4a4582b34f8 303 SUPERFAMILY SSF52540 9 210 9.09E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16210 dcad38acdf725210a745d4a4582b34f8 303 Pfam PF00005 ABC transporter 20 157 1.1E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS16210 dcad38acdf725210a745d4a4582b34f8 303 Gene3D G3DSA:3.40.50.300 3 216 3.4E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20610 2cbc7b94af9d8785c3c535692ce94644 325 Gene3D G3DSA:3.90.550.10 3 202 2.4E-42 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS20610 2cbc7b94af9d8785c3c535692ce94644 325 Pfam PF00535 Glycosyl transferase family 2 5 113 3.6E-33 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS20610 2cbc7b94af9d8785c3c535692ce94644 325 SUPERFAMILY SSF53448 3 231 1.41E-44 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS26040 c070592a69f17f3b883264ed849c834d 328 Pfam PF14016 Protein of unknown function (DUF4232) 187 324 5.1E-26 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 LK06_RS10665 3f6e50cff75bb25586f7fc24b7e43243 314 SUPERFAMILY SSF56601 50 278 2.99E-25 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS10665 3f6e50cff75bb25586f7fc24b7e43243 314 Gene3D G3DSA:3.40.710.10 50 107 2.2E-4 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS10665 3f6e50cff75bb25586f7fc24b7e43243 314 Gene3D G3DSA:3.40.710.10 118 281 7.4E-19 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS10665 3f6e50cff75bb25586f7fc24b7e43243 314 Pfam PF13354 Beta-lactamase enzyme family 119 254 1.5E-8 T 06-07-2017 LK06_RS19870 43af8dd63380736a958b81da3b513e58 943 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 625 724 2.1E-31 T 06-07-2017 IPR032722 Deaminase, Xanthomonas XOO_2897-like LK06_RS19870 43af8dd63380736a958b81da3b513e58 943 Pfam PF14435 SUKH-4 immunity protein 761 937 4.0E-41 T 06-07-2017 IPR025851 SUKH-4 immunity protein LK06_RS23465 add9802446252ac7390c232a6554e0ce 117 Pfam PF12823 Domain of unknown function (DUF3817) 9 95 1.1E-22 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane LK06_RS23465 add9802446252ac7390c232a6554e0ce 117 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 13 93 4.8E-23 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane LK06_RS25785 6fe827b2051f6ecefa55d1df287d42f7 201 Pfam PF13649 Methyltransferase domain 39 130 1.9E-14 T 06-07-2017 LK06_RS25785 6fe827b2051f6ecefa55d1df287d42f7 201 Gene3D G3DSA:3.40.50.150 17 198 5.9E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25785 6fe827b2051f6ecefa55d1df287d42f7 201 SUPERFAMILY SSF53335 1 193 1.0E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26975 e5ae22322b0537f703a751865c92e8cf 190 SUPERFAMILY SSF55729 46 172 1.05E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS26975 e5ae22322b0537f703a751865c92e8cf 190 Gene3D G3DSA:3.40.630.30 57 175 1.0E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS05535 d20fa7075fb5c1ad5916796df302d7d1 783 Gene3D G3DSA:1.10.443.10 457 649 8.5E-23 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS05535 d20fa7075fb5c1ad5916796df302d7d1 783 Pfam PF00589 Phage integrase family 459 643 1.0E-15 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS05535 d20fa7075fb5c1ad5916796df302d7d1 783 SUPERFAMILY SSF56349 461 650 2.62E-20 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS00015 5104107facce6442fc7257099492e51f 339 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 245 334 4.6E-21 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS00015 5104107facce6442fc7257099492e51f 339 Gene3D G3DSA:3.40.47.10 4 168 3.4E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS00015 5104107facce6442fc7257099492e51f 339 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 114 189 1.2E-8 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LK06_RS00015 5104107facce6442fc7257099492e51f 339 SUPERFAMILY SSF53901 9 335 2.45E-29 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS00015 5104107facce6442fc7257099492e51f 339 Gene3D G3DSA:3.40.47.10 169 336 1.3E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS19920 048c3ec5e3c156e10c10a2bc53516e6b 216 SUPERFAMILY SSF109998 32 157 1.02E-17 T 06-07-2017 IPR027304 Trigger factor/SurA domain LK06_RS19920 048c3ec5e3c156e10c10a2bc53516e6b 216 Pfam PF13624 SurA N-terminal domain 8 153 1.2E-13 T 06-07-2017 LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 Gene3D G3DSA:1.20.1250.20 271 430 6.0E-18 T 06-07-2017 LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 Gene3D G3DSA:1.20.1250.20 515 543 6.0E-18 T 06-07-2017 LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 Pfam PF07690 Major Facilitator Superfamily 26 416 2.0E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 440 3.1E-71 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 PRINTS PR01036 Tetracycline resistance protein TetB signature 407 426 1.9E-5 T 06-07-2017 LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 1.9E-5 T 06-07-2017 LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 1.9E-5 T 06-07-2017 LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 1.9E-5 T 06-07-2017 LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 SUPERFAMILY SSF103473 255 426 1.96E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 SUPERFAMILY SSF103473 509 538 1.96E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 SUPERFAMILY SSF103473 11 205 1.96E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS23590 6cde9a1642b8e01a4ff8e953ed100e8a 556 Gene3D G3DSA:1.20.1250.20 18 204 1.6E-33 T 06-07-2017 LK06_RS31205 a64f73db002bc403a47689a3644d23f5 333 SUPERFAMILY SSF51735 7 324 2.39E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31205 a64f73db002bc403a47689a3644d23f5 333 Gene3D G3DSA:3.90.25.10 193 320 8.3E-28 T 06-07-2017 LK06_RS31205 a64f73db002bc403a47689a3644d23f5 333 Gene3D G3DSA:3.40.50.720 9 192 1.9E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31205 a64f73db002bc403a47689a3644d23f5 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 312 1.3E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS21355 c7ced3153a151c054df54ed393a80db7 450 Pfam PF01594 Domain of unknown function DUF20 81 405 2.9E-59 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like LK06_RS10930 71dfff77b08e0a1c58dc95655f927f7c 314 Gene3D G3DSA:3.40.50.720 108 274 4.0E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS10930 71dfff77b08e0a1c58dc95655f927f7c 314 SUPERFAMILY SSF52283 30 123 7.05E-12 T 06-07-2017 LK06_RS10930 71dfff77b08e0a1c58dc95655f927f7c 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 273 7.9E-45 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LK06_RS10930 71dfff77b08e0a1c58dc95655f927f7c 314 SUPERFAMILY SSF51735 99 274 4.23E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS10930 71dfff77b08e0a1c58dc95655f927f7c 314 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 29 304 2.8E-6 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 LK06_RS10930 71dfff77b08e0a1c58dc95655f927f7c 314 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 212 228 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LK06_RS10930 71dfff77b08e0a1c58dc95655f927f7c 314 Gene3D G3DSA:3.40.50.720 3 107 2.0E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 PRINTS PR00359 B-class P450 signature 166 181 4.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 PRINTS PR00359 B-class P450 signature 149 165 4.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 PRINTS PR00359 B-class P450 signature 362 373 4.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 PRINTS PR00359 B-class P450 signature 303 330 4.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 PRINTS PR00359 B-class P450 signature 331 346 4.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 PRINTS PR00359 B-class P450 signature 353 362 4.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 PRINTS PR00359 B-class P450 signature 208 230 4.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 PRINTS PR00359 B-class P450 signature 286 297 4.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 PRINTS PR00359 B-class P450 signature 102 113 4.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 Gene3D G3DSA:1.10.630.10 7 410 1.8E-110 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 Pfam PF00067 Cytochrome P450 289 379 1.5E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS08610 ad514bb9f3f5f8d5931da47788ea85a1 411 SUPERFAMILY SSF48264 20 410 5.63E-81 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS21105 55abd9a1716309d1f258a4c8a68608d3 445 Pfam PF02687 FtsX-like permease family 56 173 6.6E-13 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS21105 55abd9a1716309d1f258a4c8a68608d3 445 Pfam PF02687 FtsX-like permease family 327 434 2.3E-11 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS16865 c3acd719417de6d8ab6199b023ff9747 761 SUPERFAMILY SSF48371 118 214 2.1E-6 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS16865 c3acd719417de6d8ab6199b023ff9747 761 SUPERFAMILY SSF48371 499 651 2.1E-6 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS16865 c3acd719417de6d8ab6199b023ff9747 761 Gene3D G3DSA:1.25.10.10 452 470 7.3E-5 T 06-07-2017 IPR011989 Armadillo-like helical LK06_RS16865 c3acd719417de6d8ab6199b023ff9747 761 Gene3D G3DSA:1.25.10.10 502 559 7.3E-5 T 06-07-2017 IPR011989 Armadillo-like helical LK06_RS16865 c3acd719417de6d8ab6199b023ff9747 761 Gene3D G3DSA:1.25.10.10 119 155 7.3E-5 T 06-07-2017 IPR011989 Armadillo-like helical LK06_RS20880 36a53da9122af0527d7f181ceb431de6 264 Gene3D G3DSA:3.90.226.10 8 204 2.3E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS20880 36a53da9122af0527d7f181ceb431de6 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 262 4.5E-56 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS20880 36a53da9122af0527d7f181ceb431de6 264 SUPERFAMILY SSF52096 8 263 1.71E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS20880 36a53da9122af0527d7f181ceb431de6 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 105 125 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 LK06_RS20880 36a53da9122af0527d7f181ceb431de6 264 Gene3D G3DSA:1.10.12.10 206 264 6.3E-18 T 06-07-2017 IPR014748 Crontonase, C-terminal LK06_RS11960 ad8db993c67dbf93addce97459e239f4 186 SUPERFAMILY SSF54637 21 174 7.78E-43 T 06-07-2017 IPR029069 HotDog domain LK06_RS11960 ad8db993c67dbf93addce97459e239f4 186 Pfam PF03061 Thioesterase superfamily 41 111 7.8E-20 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 LK06_RS11960 ad8db993c67dbf93addce97459e239f4 186 Gene3D G3DSA:3.10.129.10 21 173 1.5E-51 T 06-07-2017 IPR029069 HotDog domain LK06_RS18750 426140bae2dea627ce04bfbbf09fb987 385 Pfam PF13458 Periplasmic binding protein 7 326 1.3E-27 T 06-07-2017 IPR028081 Leucine-binding protein domain LK06_RS18750 426140bae2dea627ce04bfbbf09fb987 385 Gene3D G3DSA:3.40.50.2300 5 179 3.7E-19 T 06-07-2017 LK06_RS18750 426140bae2dea627ce04bfbbf09fb987 385 SUPERFAMILY SSF53822 7 324 1.14E-26 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS23735 6bfab544f5916e5e404da7d6a5fbaead 455 SUPERFAMILY SSF143548 17 159 2.35E-47 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 LK06_RS23735 6bfab544f5916e5e404da7d6a5fbaead 455 Pfam PF03313 Serine dehydratase alpha chain 188 449 2.0E-105 T 06-07-2017 IPR005130 Serine dehydratase-like, alpha subunit LK06_RS23735 6bfab544f5916e5e404da7d6a5fbaead 455 Pfam PF03315 Serine dehydratase beta chain 4 157 1.7E-60 T 06-07-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 LK06_RS23735 6bfab544f5916e5e404da7d6a5fbaead 455 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 452 7.9E-211 T 06-07-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 LK06_RS23735 6bfab544f5916e5e404da7d6a5fbaead 455 Gene3D G3DSA:3.30.1330.90 11 159 1.4E-56 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 LK06_RS20215 66f1e0d7a6827eeacaf43a7b4c323cd3 592 SUPERFAMILY SSF51905 482 542 5.83E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20215 66f1e0d7a6827eeacaf43a7b4c323cd3 592 SUPERFAMILY SSF51905 6 168 5.83E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20215 66f1e0d7a6827eeacaf43a7b4c323cd3 592 SUPERFAMILY SSF51905 198 313 5.83E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20215 66f1e0d7a6827eeacaf43a7b4c323cd3 592 Gene3D G3DSA:3.50.50.60 6 128 2.2E-84 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20215 66f1e0d7a6827eeacaf43a7b4c323cd3 592 Gene3D G3DSA:3.50.50.60 426 427 2.2E-84 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20215 66f1e0d7a6827eeacaf43a7b4c323cd3 592 Gene3D G3DSA:3.50.50.60 476 544 2.2E-84 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20215 66f1e0d7a6827eeacaf43a7b4c323cd3 592 Gene3D G3DSA:3.50.50.60 206 311 2.2E-84 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20215 66f1e0d7a6827eeacaf43a7b4c323cd3 592 Pfam PF05199 GMC oxidoreductase 480 537 3.7E-13 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LK06_RS20215 66f1e0d7a6827eeacaf43a7b4c323cd3 592 Pfam PF00732 GMC oxidoreductase 8 288 1.6E-11 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LK06_RS04510 6c8e7df51ac2140928c3f0c723883ba5 366 PRINTS PR00095 Anthranilate synthase component I signature 290 304 2.2E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS04510 6c8e7df51ac2140928c3f0c723883ba5 366 PRINTS PR00095 Anthranilate synthase component I signature 194 207 2.2E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS04510 6c8e7df51ac2140928c3f0c723883ba5 366 PRINTS PR00095 Anthranilate synthase component I signature 274 288 2.2E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LK06_RS04510 6c8e7df51ac2140928c3f0c723883ba5 366 SUPERFAMILY SSF56322 55 342 4.19E-91 T 06-07-2017 IPR005801 ADC synthase GO:0009058 LK06_RS04510 6c8e7df51ac2140928c3f0c723883ba5 366 Pfam PF00425 chorismate binding enzyme 87 335 9.6E-74 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal LK06_RS04510 6c8e7df51ac2140928c3f0c723883ba5 366 Gene3D G3DSA:3.60.120.10 75 343 1.2E-99 T 06-07-2017 IPR005801 ADC synthase GO:0009058 LK06_RS17020 4c6ce540f47f4594e44b12559b5c4376 226 Gene3D G3DSA:3.40.50.880 3 222 7.5E-41 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS17020 4c6ce540f47f4594e44b12559b5c4376 226 SUPERFAMILY SSF52317 3 221 1.29E-69 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS17020 4c6ce540f47f4594e44b12559b5c4376 226 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 221 40.701 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS17020 4c6ce540f47f4594e44b12559b5c4376 226 PIRSF PIRSF001586 1 226 1.2E-83 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS17020 4c6ce540f47f4594e44b12559b5c4376 226 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 204 1.6E-33 T 06-07-2017 LK06_RS17020 4c6ce540f47f4594e44b12559b5c4376 226 SMART SM01211 2 223 2.0E-122 T 06-07-2017 LK06_RS17020 4c6ce540f47f4594e44b12559b5c4376 226 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 222 1.1E-81 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 LK06_RS12195 9943f37cf3cde21ebef79700cacba75c 73 Gene3D G3DSA:2.40.50.140 2 73 8.0E-40 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS12195 9943f37cf3cde21ebef79700cacba75c 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 2.4E-29 T 06-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 LK06_RS12195 9943f37cf3cde21ebef79700cacba75c 73 SMART SM00316 5 73 2.0E-5 T 06-07-2017 IPR022967 RNA-binding domain, S1 LK06_RS12195 9943f37cf3cde21ebef79700cacba75c 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.966 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 LK06_RS12195 9943f37cf3cde21ebef79700cacba75c 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 2.4E-38 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 LK06_RS12195 9943f37cf3cde21ebef79700cacba75c 73 SUPERFAMILY SSF50249 4 73 5.88E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS04480 49aa31ebe947089278e90ef14adb1529 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.5E-38 T 06-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 LK06_RS31125 0a10cf4cf156efc7d375a1a78c208a20 220 SUPERFAMILY SSF63817 73 220 4.19E-17 T 06-07-2017 IPR023365 Sortase domain LK06_RS31125 0a10cf4cf156efc7d375a1a78c208a20 220 Gene3D G3DSA:2.40.260.10 111 220 2.0E-10 T 06-07-2017 IPR023365 Sortase domain LK06_RS31125 0a10cf4cf156efc7d375a1a78c208a20 220 Pfam PF04203 Sortase family 81 220 1.2E-17 T 06-07-2017 IPR005754 Sortase family LK06_RS21765 283561f18ddbb37a43fc359929265044 152 Pfam PF13581 Histidine kinase-like ATPase domain 33 145 2.2E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21765 283561f18ddbb37a43fc359929265044 152 SUPERFAMILY SSF55874 55 148 1.61E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS26140 e8efaf69d6ad94ed4ac63797aa884a68 355 SUPERFAMILY SSF51197 41 333 6.59E-54 T 06-07-2017 LK06_RS26140 e8efaf69d6ad94ed4ac63797aa884a68 355 Gene3D G3DSA:2.60.120.620 28 279 4.4E-32 T 06-07-2017 LK06_RS26140 e8efaf69d6ad94ed4ac63797aa884a68 355 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 51 266 4.0E-10 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase LK06_RS15760 226d07d0b42467606dafc966a962605c 446 Pfam PF01580 FtsK/SpoIIIE family 272 327 2.3E-8 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS15760 226d07d0b42467606dafc966a962605c 446 Pfam PF01580 FtsK/SpoIIIE family 145 264 4.3E-16 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LK06_RS15760 226d07d0b42467606dafc966a962605c 446 SUPERFAMILY SSF52540 136 404 1.21E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15760 226d07d0b42467606dafc966a962605c 446 Gene3D G3DSA:3.40.50.300 151 361 3.6E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26585 48b8f3c7ed65aaac412b86afff5a7203 338 SUPERFAMILY SSF89372 5 285 7.32E-20 T 06-07-2017 LK06_RS26585 48b8f3c7ed65aaac412b86afff5a7203 338 Gene3D G3DSA:2.120.10.70 101 218 1.1E-4 T 06-07-2017 LK06_RS20800 b1352005980f83a0f2539bb37ea44b0a 328 SUPERFAMILY SSF51569 70 308 9.42E-74 T 06-07-2017 LK06_RS20800 b1352005980f83a0f2539bb37ea44b0a 328 Pfam PF01791 DeoC/LacD family aldolase 65 306 6.6E-27 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 LK06_RS20800 b1352005980f83a0f2539bb37ea44b0a 328 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 72 290 6.9E-55 T 06-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 LK06_RS20800 b1352005980f83a0f2539bb37ea44b0a 328 Gene3D G3DSA:3.20.20.70 63 320 4.8E-93 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS20800 b1352005980f83a0f2539bb37ea44b0a 328 SMART SM01133 69 309 9.3E-72 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 LK06_RS27510 664a5f7e1fe07168d81290115d2fe38a 73 Pfam PF00589 Phage integrase family 2 38 6.0E-7 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS27510 664a5f7e1fe07168d81290115d2fe38a 73 SUPERFAMILY SSF56349 1 43 1.09E-12 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS27510 664a5f7e1fe07168d81290115d2fe38a 73 Gene3D G3DSA:1.10.443.10 2 51 2.2E-12 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS11695 bbed797ceaface6b156c3fd354f3d9fe 554 Gene3D G3DSA:3.90.550.10 4 232 7.7E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11695 bbed797ceaface6b156c3fd354f3d9fe 554 SUPERFAMILY SSF53448 4 213 2.19E-45 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS11695 bbed797ceaface6b156c3fd354f3d9fe 554 Pfam PF00535 Glycosyl transferase family 2 8 133 7.5E-32 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS13185 c5faae41f28fa55f7f739e21fa1e47f6 235 SUPERFAMILY SSF142823 7 213 2.35E-36 T 06-07-2017 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 LK06_RS13185 c5faae41f28fa55f7f739e21fa1e47f6 235 Pfam PF04029 2-phosphosulpholactate phosphatase 13 212 4.6E-30 T 06-07-2017 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 LK06_RS13185 c5faae41f28fa55f7f739e21fa1e47f6 235 Gene3D G3DSA:3.90.1560.10 7 217 1.5E-44 T 06-07-2017 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 LK06_RS17920 d5344215aabb82d9c5ad9c43e65fdabc 383 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 73 128 1.6E-9 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS17920 d5344215aabb82d9c5ad9c43e65fdabc 383 Gene3D G3DSA:1.10.150.130 73 172 9.1E-20 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS17920 d5344215aabb82d9c5ad9c43e65fdabc 383 Pfam PF00589 Phage integrase family 185 361 2.4E-30 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS17920 d5344215aabb82d9c5ad9c43e65fdabc 383 SUPERFAMILY SSF56349 73 369 9.18E-71 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS17920 d5344215aabb82d9c5ad9c43e65fdabc 383 Gene3D G3DSA:1.10.443.10 178 369 3.0E-47 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS18265 cd178b03d63e6a352a99c0d7e753075e 291 Pfam PF02358 Trehalose-phosphatase 44 257 2.1E-26 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 LK06_RS18265 cd178b03d63e6a352a99c0d7e753075e 291 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 40 287 1.1E-30 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 LK06_RS18265 cd178b03d63e6a352a99c0d7e753075e 291 Gene3D G3DSA:3.40.50.1000 41 120 9.8E-33 T 06-07-2017 IPR023214 HAD-like domain LK06_RS18265 cd178b03d63e6a352a99c0d7e753075e 291 Gene3D G3DSA:3.40.50.1000 200 289 9.8E-33 T 06-07-2017 IPR023214 HAD-like domain LK06_RS18265 cd178b03d63e6a352a99c0d7e753075e 291 SUPERFAMILY SSF56784 42 287 2.6E-33 T 06-07-2017 IPR023214 HAD-like domain LK06_RS02580 5c4df24b4184b83dabb2a755e0e08052 356 Pfam PF01609 Transposase DDE domain 96 324 7.1E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS02580 5c4df24b4184b83dabb2a755e0e08052 356 Pfam PF13808 DDE_Tnp_1-associated 2 85 6.0E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS15895 e80ee10bf4ef20f80ad0acb8cb78e482 357 Pfam PF13614 AAA domain 80 256 4.4E-58 T 06-07-2017 IPR025669 AAA domain LK06_RS15895 e80ee10bf4ef20f80ad0acb8cb78e482 357 Gene3D G3DSA:3.40.50.300 81 329 6.1E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS15895 e80ee10bf4ef20f80ad0acb8cb78e482 357 SUPERFAMILY SSF52540 80 329 1.65E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13975 df7d7804d689a57664a5bb3989fe87cb 543 Gene3D G3DSA:3.40.50.1820 92 178 4.0E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS13975 df7d7804d689a57664a5bb3989fe87cb 543 Gene3D G3DSA:3.40.50.1820 410 530 4.0E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS13975 df7d7804d689a57664a5bb3989fe87cb 543 Gene3D G3DSA:3.40.50.1820 222 348 4.0E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS13975 df7d7804d689a57664a5bb3989fe87cb 543 Pfam PF00561 alpha/beta hydrolase fold 127 515 4.0E-35 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS13975 df7d7804d689a57664a5bb3989fe87cb 543 SUPERFAMILY SSF53474 402 515 4.27E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS13975 df7d7804d689a57664a5bb3989fe87cb 543 SUPERFAMILY SSF53474 121 179 4.27E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS13975 df7d7804d689a57664a5bb3989fe87cb 543 SUPERFAMILY SSF53474 224 278 4.27E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS02745 0719f2b7c9855d57ab015d79263effe2 383 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 229 242 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 LK06_RS02745 0719f2b7c9855d57ab015d79263effe2 383 SUPERFAMILY SSF53383 2 381 3.06E-91 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS02745 0719f2b7c9855d57ab015d79263effe2 383 Pfam PF00155 Aminotransferase class I and II 29 379 2.7E-49 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS02745 0719f2b7c9855d57ab015d79263effe2 383 Gene3D G3DSA:3.90.1150.10 252 382 5.0E-24 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS02745 0719f2b7c9855d57ab015d79263effe2 383 Gene3D G3DSA:3.40.640.10 40 251 2.6E-61 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS16320 24325112556428012d6234b44ee04daa 275 Gene3D G3DSA:3.20.20.190 3 270 4.3E-76 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS16320 24325112556428012d6234b44ee04daa 275 SUPERFAMILY SSF51695 9 271 2.62E-66 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS16320 24325112556428012d6234b44ee04daa 275 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 267 2.6E-44 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 LK06_RS12775 8606cc76343d6aeb57efbd8aea25f254 319 SMART SM00382 48 223 3.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS12775 8606cc76343d6aeb57efbd8aea25f254 319 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS12775 8606cc76343d6aeb57efbd8aea25f254 319 Gene3D G3DSA:3.40.50.300 21 237 6.8E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12775 8606cc76343d6aeb57efbd8aea25f254 319 Pfam PF00005 ABC transporter 40 175 4.4E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS12775 8606cc76343d6aeb57efbd8aea25f254 319 SUPERFAMILY SSF52540 25 236 2.81E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23885 a428d37e3d7196c2a70262a29f0c8793 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 8.2E-17 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 LK06_RS23885 a428d37e3d7196c2a70262a29f0c8793 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 24.205 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 LK06_RS23885 a428d37e3d7196c2a70262a29f0c8793 98 SUPERFAMILY SSF141000 4 94 1.57E-27 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 LK06_RS23885 a428d37e3d7196c2a70262a29f0c8793 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 1.9E-24 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 LK06_RS30460 bf49931a918a7859d7bcfc64e5ae80df 183 Pfam PF10400 Virulence activator alpha C-term 93 173 3.5E-22 T 06-07-2017 IPR018309 Transcription regulator PadR, C-terminal LK06_RS30460 bf49931a918a7859d7bcfc64e5ae80df 183 Gene3D G3DSA:1.10.10.10 1 85 2.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS30460 bf49931a918a7859d7bcfc64e5ae80df 183 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 1.2E-11 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal LK06_RS30460 bf49931a918a7859d7bcfc64e5ae80df 183 SUPERFAMILY SSF46785 2 176 2.48E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11750 6cf5000d06bc27651f0f9df4b2668032 230 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 100 9.0E-20 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 LK06_RS11750 6cf5000d06bc27651f0f9df4b2668032 230 Gene3D G3DSA:3.30.160.100 2 100 4.2E-26 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 LK06_RS11750 6cf5000d06bc27651f0f9df4b2668032 230 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 2 104 1.7E-21 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 LK06_RS11750 6cf5000d06bc27651f0f9df4b2668032 230 SUPERFAMILY SSF69754 3 110 1.11E-22 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 LK06_RS11750 6cf5000d06bc27651f0f9df4b2668032 230 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 154 207 2.3E-21 T 06-07-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal LK06_RS26785 00061e4e82642becfd9dc08f4a8a715f 307 SUPERFAMILY SSF53850 39 305 4.67E-48 T 06-07-2017 LK06_RS26785 00061e4e82642becfd9dc08f4a8a715f 307 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 40 302 4.2E-53 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 LK06_RS26785 00061e4e82642becfd9dc08f4a8a715f 307 Gene3D G3DSA:3.40.190.10 257 306 4.6E-38 T 06-07-2017 LK06_RS26785 00061e4e82642becfd9dc08f4a8a715f 307 Gene3D G3DSA:3.40.190.10 36 144 4.6E-38 T 06-07-2017 LK06_RS26785 00061e4e82642becfd9dc08f4a8a715f 307 Gene3D G3DSA:3.40.190.120 145 245 1.3E-27 T 06-07-2017 LK06_RS06025 7c1be201e44e0a6f19a32b47599509b2 467 Pfam PF01523 Putative modulator of DNA gyrase 24 326 6.4E-30 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 LK06_RS06025 7c1be201e44e0a6f19a32b47599509b2 467 SUPERFAMILY SSF111283 12 460 3.79E-63 T 06-07-2017 LK06_RS07695 e73c5eb18d78bff291dc35c8df07199a 394 Pfam PF02445 Quinolinate synthetase A protein 52 392 7.9E-106 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 LK06_RS07695 e73c5eb18d78bff291dc35c8df07199a 394 SUPERFAMILY SSF142754 52 393 4.58E-93 T 06-07-2017 LK06_RS07695 e73c5eb18d78bff291dc35c8df07199a 394 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 46 393 2.0E-98 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 LK06_RS07695 e73c5eb18d78bff291dc35c8df07199a 394 Hamap MF_00569 Quinolinate synthase A [nadA]. 43 393 57.092 T 06-07-2017 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 LK06_RS05145 728235e64fae309b5edd52d57f69a107 228 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 203 2.2E-96 T 06-07-2017 IPR022492 Phosphomutase MSMEG4193, putative LK06_RS05145 728235e64fae309b5edd52d57f69a107 228 SMART SM00855 3 162 2.1E-22 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS05145 728235e64fae309b5edd52d57f69a107 228 SUPERFAMILY SSF53254 1 205 1.07E-45 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS05145 728235e64fae309b5edd52d57f69a107 228 Gene3D G3DSA:3.40.50.1240 1 207 7.6E-47 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS05145 728235e64fae309b5edd52d57f69a107 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 202 1.5E-48 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS15435 1d8e5e902f20d38bab3d731b26e13d88 306 Gene3D G3DSA:3.90.550.10 18 208 2.5E-40 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS15435 1d8e5e902f20d38bab3d731b26e13d88 306 Pfam PF12804 MobA-like NTP transferase domain 20 165 1.8E-30 T 06-07-2017 IPR025877 MobA-like NTP transferase LK06_RS15435 1d8e5e902f20d38bab3d731b26e13d88 306 SUPERFAMILY SSF53448 18 197 2.29E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS05120 c83fd922eb55d237a7cd933b1d0e5c3a 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 5.8E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05120 c83fd922eb55d237a7cd933b1d0e5c3a 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 5.8E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05120 c83fd922eb55d237a7cd933b1d0e5c3a 223 SUPERFAMILY SSF46785 4 70 2.95E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05120 c83fd922eb55d237a7cd933b1d0e5c3a 223 Gene3D G3DSA:1.20.120.530 88 220 2.8E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS05120 c83fd922eb55d237a7cd933b1d0e5c3a 223 Pfam PF07729 FCD domain 92 213 2.7E-24 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS05120 c83fd922eb55d237a7cd933b1d0e5c3a 223 SMART SM00345 7 66 5.4E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05120 c83fd922eb55d237a7cd933b1d0e5c3a 223 Gene3D G3DSA:1.10.10.10 4 71 1.9E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05120 c83fd922eb55d237a7cd933b1d0e5c3a 223 SMART SM00895 92 214 1.0E-17 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS05120 c83fd922eb55d237a7cd933b1d0e5c3a 223 SUPERFAMILY SSF48008 89 221 6.28E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS05120 c83fd922eb55d237a7cd933b1d0e5c3a 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 6.6E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS10760 9a8acb63504738340c4e44da3d0af841 590 Pfam PF04183 IucA / IucC family 140 389 2.5E-79 T 06-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 LK06_RS10760 9a8acb63504738340c4e44da3d0af841 590 Pfam PF06276 Ferric iron reductase FhuF-like transporter 411 567 7.6E-41 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain LK06_RS27070 d2895dcf4df86b9d4a6871789d4dbca8 537 SUPERFAMILY SSF49384 431 534 2.37E-25 T 06-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 LK06_RS27070 d2895dcf4df86b9d4a6871789d4dbca8 537 Pfam PF00553 Cellulose binding domain 436 534 3.9E-22 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 LK06_RS27070 d2895dcf4df86b9d4a6871789d4dbca8 537 SMART SM00637 436 534 2.9E-28 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 LK06_RS27070 d2895dcf4df86b9d4a6871789d4dbca8 537 Gene3D G3DSA:2.60.40.290 435 534 7.6E-27 T 06-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 LK06_RS25930 caf95850d708ae3ab45a0f4a5db6ca60 476 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 24 476 1.8E-118 T 06-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase LK06_RS25930 caf95850d708ae3ab45a0f4a5db6ca60 476 Pfam PF13727 CoA-binding domain 93 212 3.3E-6 T 06-07-2017 LK06_RS25930 caf95850d708ae3ab45a0f4a5db6ca60 476 Pfam PF02397 Bacterial sugar transferase 283 470 3.7E-54 T 06-07-2017 IPR003362 Bacterial sugar transferase LK06_RS29905 7078b66e300655578986f81ece7b0548 130 Gene3D G3DSA:3.10.180.10 9 124 4.2E-25 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS29905 7078b66e300655578986f81ece7b0548 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 113 3.2E-11 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS29905 7078b66e300655578986f81ece7b0548 130 SUPERFAMILY SSF54593 11 121 4.97E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS14600 b4ee46229a970c991fa7b83510ebc2c5 286 SUPERFAMILY SSF140959 30 285 3.53E-78 T 06-07-2017 LK06_RS14600 b4ee46229a970c991fa7b83510ebc2c5 286 Pfam PF03301 Tryptophan 2,3-dioxygenase 22 286 2.7E-79 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 LK06_RS14600 b4ee46229a970c991fa7b83510ebc2c5 286 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 24 286 36.76 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 LK06_RS04680 6de4ca76d0ade936ffe82dd343d03add 265 Pfam PF04205 FMN-binding domain 73 144 2.3E-8 T 06-07-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 LK06_RS04680 6de4ca76d0ade936ffe82dd343d03add 265 Pfam PF04205 FMN-binding domain 189 260 2.8E-9 T 06-07-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 LK06_RS04680 6de4ca76d0ade936ffe82dd343d03add 265 SMART SM00900 71 147 6.4E-12 T 06-07-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 LK06_RS04680 6de4ca76d0ade936ffe82dd343d03add 265 SMART SM00900 187 263 3.9E-11 T 06-07-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 LK06_RS07310 922053e49bc27e9587eb6d37eb4a0945 473 Pfam PF08245 Mur ligase middle domain 122 307 2.0E-27 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS07310 922053e49bc27e9587eb6d37eb4a0945 473 Gene3D G3DSA:3.90.190.20 328 468 1.6E-44 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS07310 922053e49bc27e9587eb6d37eb4a0945 473 SUPERFAMILY SSF53244 328 471 7.32E-37 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LK06_RS07310 922053e49bc27e9587eb6d37eb4a0945 473 SUPERFAMILY SSF53623 117 324 4.19E-49 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS07310 922053e49bc27e9587eb6d37eb4a0945 473 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 14 469 8.6E-118 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS07310 922053e49bc27e9587eb6d37eb4a0945 473 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 13 471 33.852 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LK06_RS07310 922053e49bc27e9587eb6d37eb4a0945 473 Gene3D G3DSA:3.40.1190.10 103 325 2.2E-68 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 LK06_RS07310 922053e49bc27e9587eb6d37eb4a0945 473 SUPERFAMILY SSF51984 9 103 4.71E-16 T 06-07-2017 LK06_RS07310 922053e49bc27e9587eb6d37eb4a0945 473 Gene3D G3DSA:3.40.50.720 9 102 5.3E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS20710 6b71339424a5a836052fb55029edd25f 306 Pfam PF03547 Membrane transport protein 10 132 1.5E-8 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 LK06_RS20710 6b71339424a5a836052fb55029edd25f 306 Pfam PF03547 Membrane transport protein 160 298 5.2E-15 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 LK06_RS10860 c4b8d72d15c25e09246553d3d19e08e2 493 SUPERFAMILY SSF48452 251 338 3.98E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS10860 c4b8d72d15c25e09246553d3d19e08e2 493 Gene3D G3DSA:1.25.40.10 253 327 4.8E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS10860 c4b8d72d15c25e09246553d3d19e08e2 493 Gene3D G3DSA:1.25.40.10 376 483 4.8E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS20060 52273f86c329e767ceaef91054ff9fa2 424 SUPERFAMILY SSF53474 120 399 2.92E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS20060 52273f86c329e767ceaef91054ff9fa2 424 Pfam PF12697 Alpha/beta hydrolase family 131 393 5.9E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS20060 52273f86c329e767ceaef91054ff9fa2 424 Gene3D G3DSA:3.40.50.1820 94 401 5.7E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS07130 50cafbe3ac473ad1083ac6f14d98d080 131 Gene3D G3DSA:3.30.1330.40 4 128 3.3E-29 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS07130 50cafbe3ac473ad1083ac6f14d98d080 131 Pfam PF01042 Endoribonuclease L-PSP 18 125 1.9E-12 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family LK06_RS07130 50cafbe3ac473ad1083ac6f14d98d080 131 SUPERFAMILY SSF55298 5 127 3.14E-22 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LK06_RS13980 82892cf80a08e3959241c78d3f88b885 401 Pfam PF13177 DNA polymerase III, delta subunit 40 186 7.3E-33 T 06-07-2017 LK06_RS13980 82892cf80a08e3959241c78d3f88b885 401 SUPERFAMILY SSF52540 4 227 3.55E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS13980 82892cf80a08e3959241c78d3f88b885 401 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 40 223 9.9E-55 T 06-07-2017 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LK06_RS13980 82892cf80a08e3959241c78d3f88b885 401 Gene3D G3DSA:3.40.50.300 4 186 1.2E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21515 8b50cedab088d333cf6cd3127755e758 250 SUPERFAMILY SSF53067 1 247 2.49E-39 T 06-07-2017 LK06_RS21515 8b50cedab088d333cf6cd3127755e758 250 Gene3D G3DSA:3.30.420.40 107 246 6.9E-39 T 06-07-2017 LK06_RS21515 8b50cedab088d333cf6cd3127755e758 250 Pfam PF00480 ROK family 171 244 9.6E-5 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS21515 8b50cedab088d333cf6cd3127755e758 250 Pfam PF00480 ROK family 4 161 1.6E-16 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS21515 8b50cedab088d333cf6cd3127755e758 250 Gene3D G3DSA:3.30.420.40 1 106 2.3E-40 T 06-07-2017 LK06_RS00840 a015721e4e75ad0ddf929d04a088054b 423 SUPERFAMILY SSF54909 59 416 1.14E-94 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS00840 a015721e4e75ad0ddf929d04a088054b 423 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 66 410 1.7E-95 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LK06_RS00840 a015721e4e75ad0ddf929d04a088054b 423 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 10 421 9.3E-145 T 06-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 LK06_RS00840 a015721e4e75ad0ddf929d04a088054b 423 Pfam PF04261 Dyp-type peroxidase family 66 410 6.2E-105 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LK06_RS21350 41ee3805ad0e0effc724b5da51c56991 244 Pfam PF01464 Transglycosylase SLT domain 165 231 5.2E-8 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 LK06_RS21350 41ee3805ad0e0effc724b5da51c56991 244 SUPERFAMILY SSF53955 171 239 2.62E-11 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS19055 18e64f7a0ae215fc88177326c951460d 285 SUPERFAMILY SSF47413 10 69 2.82E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS19055 18e64f7a0ae215fc88177326c951460d 285 Pfam PF13560 Helix-turn-helix domain 13 69 1.6E-16 T 06-07-2017 LK06_RS19055 18e64f7a0ae215fc88177326c951460d 285 Gene3D G3DSA:1.10.260.40 6 73 1.7E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS19055 18e64f7a0ae215fc88177326c951460d 285 SMART SM00530 17 72 6.2E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS27870 423ee566400cd51ca11ddc503461746c 513 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 47 491 5.0E-149 T 06-07-2017 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 LK06_RS27870 423ee566400cd51ca11ddc503461746c 513 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 42 474 1.2E-144 T 06-07-2017 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0005215|GO:0006810|GO:0016020 LK06_RS22090 d786afce9f29c30b6fd27ef8ea7436bc 285 SUPERFAMILY SSF89550 2 80 1.41E-45 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 LK06_RS22090 d786afce9f29c30b6fd27ef8ea7436bc 285 SUPERFAMILY SSF89550 163 252 1.41E-45 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 LK06_RS22090 d786afce9f29c30b6fd27ef8ea7436bc 285 SMART SM00481 3 67 6.6E-17 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 LK06_RS22090 d786afce9f29c30b6fd27ef8ea7436bc 285 Gene3D G3DSA:3.20.20.140 155 252 2.3E-39 T 06-07-2017 LK06_RS22090 d786afce9f29c30b6fd27ef8ea7436bc 285 Gene3D G3DSA:3.20.20.140 2 85 2.3E-39 T 06-07-2017 LK06_RS22090 d786afce9f29c30b6fd27ef8ea7436bc 285 Pfam PF02811 PHP domain 4 180 5.1E-10 T 06-07-2017 IPR004013 PHP domain GO:0003824 LK06_RS11735 19ced121b8656782ba3ce2322992f0a9 189 Gene3D G3DSA:3.40.630.30 1 173 5.1E-53 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS11735 19ced121b8656782ba3ce2322992f0a9 189 Pfam PF13302 Acetyltransferase (GNAT) domain 10 148 7.1E-28 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS11735 19ced121b8656782ba3ce2322992f0a9 189 SUPERFAMILY SSF55729 1 172 6.78E-43 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS05605 c64f23bbebd645bd8e323ff3d578e2b7 392 Pfam PF04188 Mannosyltransferase (PIG-V) 54 204 1.8E-5 T 06-07-2017 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 Reactome: R-HSA-162710 LK06_RS31320 670b2f7d9095548801306fef802113db 181 Gene3D G3DSA:1.20.120.520 6 134 4.9E-9 T 06-07-2017 LK06_RS31320 670b2f7d9095548801306fef802113db 181 Pfam PF01814 Hemerythrin HHE cation binding domain 3 120 4.7E-10 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 LK06_RS31330 8e3586f2928e06ef3e9e1d6b2a7901cc 65 Pfam PF14013 MT0933-like antitoxin protein 10 56 3.5E-15 T 06-07-2017 IPR028037 Antitoxin Rv0909/MT0933 LK06_RS10190 6d9f6b9ebbc11b2c6f39c97bc97a6695 142 SUPERFAMILY SSF54637 3 126 7.21E-31 T 06-07-2017 IPR029069 HotDog domain LK06_RS10190 6d9f6b9ebbc11b2c6f39c97bc97a6695 142 Gene3D G3DSA:3.10.129.10 2 126 2.2E-42 T 06-07-2017 IPR029069 HotDog domain LK06_RS10190 6d9f6b9ebbc11b2c6f39c97bc97a6695 142 Pfam PF03061 Thioesterase superfamily 17 94 4.0E-15 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 LK06_RS17300 02e7972b3b63164f67c919b8209cf94e 692 SUPERFAMILY SSF56235 42 198 6.69E-13 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS17300 02e7972b3b63164f67c919b8209cf94e 692 Pfam PF00733 Asparagine synthase 265 657 2.0E-8 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 LK06_RS17300 02e7972b3b63164f67c919b8209cf94e 692 Gene3D G3DSA:3.40.50.620 216 404 4.3E-4 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS17300 02e7972b3b63164f67c919b8209cf94e 692 Gene3D G3DSA:3.40.50.620 511 575 4.3E-4 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS17300 02e7972b3b63164f67c919b8209cf94e 692 Gene3D G3DSA:3.60.20.10 93 192 5.5E-9 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS17300 02e7972b3b63164f67c919b8209cf94e 692 SUPERFAMILY SSF52402 516 576 1.09E-8 T 06-07-2017 LK06_RS17300 02e7972b3b63164f67c919b8209cf94e 692 SUPERFAMILY SSF52402 216 233 1.09E-8 T 06-07-2017 LK06_RS17300 02e7972b3b63164f67c919b8209cf94e 692 SUPERFAMILY SSF52402 261 401 1.09E-8 T 06-07-2017 LK06_RS11405 eeca13e547fa59da840b241d5b9ca10a 297 SUPERFAMILY SSF55447 181 251 1.04E-5 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal LK06_RS11405 eeca13e547fa59da840b241d5b9ca10a 297 Gene3D G3DSA:3.30.43.10 15 55 2.7E-8 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 LK06_RS11405 eeca13e547fa59da840b241d5b9ca10a 297 Gene3D G3DSA:3.30.390.50 182 260 3.5E-5 T 06-07-2017 LK06_RS11405 eeca13e547fa59da840b241d5b9ca10a 297 Gene3D G3DSA:3.30.465.10 62 175 1.7E-26 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 LK06_RS11405 eeca13e547fa59da840b241d5b9ca10a 297 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 12 175 8.4E-40 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 LK06_RS11405 eeca13e547fa59da840b241d5b9ca10a 297 SUPERFAMILY SSF56176 9 175 6.8E-39 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 LK06_RS11175 e16876f057a05b4cf5694729cfc3b320 421 Pfam PF02378 Phosphotransferase system, EIIC 27 340 3.2E-76 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 LK06_RS10565 b356478f6cdb80b7f7ef6f41d47b9c4a 463 Gene3D G3DSA:3.40.50.300 171 380 5.5E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10565 b356478f6cdb80b7f7ef6f41d47b9c4a 463 SUPERFAMILY SSF52540 157 429 3.05E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21140 152f664f74154a03cd64fdc3c56df5eb 497 Gene3D G3DSA:3.90.1300.10 13 490 1.6E-137 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS21140 152f664f74154a03cd64fdc3c56df5eb 497 SUPERFAMILY SSF75304 9 483 4.58E-112 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS21140 152f664f74154a03cd64fdc3c56df5eb 497 Pfam PF01425 Amidase 35 471 1.7E-88 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LK06_RS15040 6639295d1157ab4f9b15da16abf44359 160 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 46 156 1.9E-25 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15040 6639295d1157ab4f9b15da16abf44359 160 Gene3D G3DSA:3.40.50.700 35 157 1.9E-29 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15040 6639295d1157ab4f9b15da16abf44359 160 SUPERFAMILY SSF56770 33 158 3.92E-46 T 06-07-2017 LK06_RS10245 2a88047b35b1a59f559e40643b5cf96f 401 Gene3D G3DSA:1.10.260.40 3 65 1.7E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10245 2a88047b35b1a59f559e40643b5cf96f 401 Gene3D G3DSA:1.25.40.10 144 273 8.5E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS10245 2a88047b35b1a59f559e40643b5cf96f 401 Pfam PF13560 Helix-turn-helix domain 5 62 2.6E-13 T 06-07-2017 LK06_RS10245 2a88047b35b1a59f559e40643b5cf96f 401 SUPERFAMILY SSF47413 3 67 8.45E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS10245 2a88047b35b1a59f559e40643b5cf96f 401 SMART SM00530 8 64 4.8E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS00255 b2271df178e861c9eed9febae01d98cd 455 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 6 421 3.3E-131 T 06-07-2017 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 LK06_RS00255 b2271df178e861c9eed9febae01d98cd 455 SUPERFAMILY SSF54675 5 131 2.69E-32 T 06-07-2017 LK06_RS00255 b2271df178e861c9eed9febae01d98cd 455 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 150 203 7.4E-7 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 LK06_RS00255 b2271df178e861c9eed9febae01d98cd 455 Gene3D G3DSA:3.20.140.10 4 358 2.0E-86 T 06-07-2017 LK06_RS00255 b2271df178e861c9eed9febae01d98cd 455 SUPERFAMILY SSF51690 133 437 1.24E-90 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 LK06_RS00255 b2271df178e861c9eed9febae01d98cd 455 PIRSF PIRSF000484 1 440 4.9E-114 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 LK06_RS17295 2bcafb4450acebc08a59acdf962a3620 474 Gene3D G3DSA:1.25.40.10 233 350 3.0E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS25450 509beb290ab1ddbf9bfff426c7464409 217 SMART SM00862 145 217 7.5E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS25450 509beb290ab1ddbf9bfff426c7464409 217 Gene3D G3DSA:3.40.50.2300 2 119 2.6E-32 T 06-07-2017 LK06_RS25450 509beb290ab1ddbf9bfff426c7464409 217 Pfam PF00072 Response regulator receiver domain 3 113 1.7E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS25450 509beb290ab1ddbf9bfff426c7464409 217 SUPERFAMILY SSF52172 2 172 2.05E-34 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS25450 509beb290ab1ddbf9bfff426c7464409 217 Gene3D G3DSA:1.10.10.10 125 217 4.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS25450 509beb290ab1ddbf9bfff426c7464409 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 6.3E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LK06_RS25450 509beb290ab1ddbf9bfff426c7464409 217 SMART SM00448 1 112 2.6E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS00305 53ef5af203f6ca5fe835d3a598f3cff8 292 Pfam PF00582 Universal stress protein family 5 139 8.3E-25 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS00305 53ef5af203f6ca5fe835d3a598f3cff8 292 Pfam PF00582 Universal stress protein family 151 289 1.1E-22 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS00305 53ef5af203f6ca5fe835d3a598f3cff8 292 SUPERFAMILY SSF52402 151 290 7.28E-22 T 06-07-2017 LK06_RS00305 53ef5af203f6ca5fe835d3a598f3cff8 292 SUPERFAMILY SSF52402 5 141 2.34E-26 T 06-07-2017 LK06_RS00305 53ef5af203f6ca5fe835d3a598f3cff8 292 PRINTS PR01438 Universal stress protein signature 2 20 1.1E-11 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00305 53ef5af203f6ca5fe835d3a598f3cff8 292 PRINTS PR01438 Universal stress protein signature 117 139 1.1E-11 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00305 53ef5af203f6ca5fe835d3a598f3cff8 292 PRINTS PR01438 Universal stress protein signature 99 111 1.1E-11 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS00305 53ef5af203f6ca5fe835d3a598f3cff8 292 Gene3D G3DSA:3.40.50.620 150 290 4.4E-24 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS00305 53ef5af203f6ca5fe835d3a598f3cff8 292 Gene3D G3DSA:3.40.50.620 4 139 4.9E-29 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS01750 6c5c5e2a0fc85a7016c2cc50789b1720 443 SUPERFAMILY SSF52777 217 438 3.56E-5 T 06-07-2017 LK06_RS01750 6c5c5e2a0fc85a7016c2cc50789b1720 443 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 6 249 7.3E-54 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 LK06_RS01750 6c5c5e2a0fc85a7016c2cc50789b1720 443 Pfam PF06974 Protein of unknown function (DUF1298) 292 436 3.3E-20 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 LK06_RS01750 6c5c5e2a0fc85a7016c2cc50789b1720 443 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 6 440 3.4E-116 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 LK06_RS23480 73e9700a5b508d0edd0036cd2777b90d 215 SUPERFAMILY SSF46689 5 86 3.28E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS23480 73e9700a5b508d0edd0036cd2777b90d 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23480 73e9700a5b508d0edd0036cd2777b90d 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23480 73e9700a5b508d0edd0036cd2777b90d 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 6.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23480 73e9700a5b508d0edd0036cd2777b90d 215 Gene3D G3DSA:1.10.357.10 6 175 6.4E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS19005 da57c10596a62dbdc8e660b304b6312b 281 Pfam PF00296 Luciferase-like monooxygenase 17 239 6.0E-42 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS19005 da57c10596a62dbdc8e660b304b6312b 281 Gene3D G3DSA:3.20.20.30 17 242 1.0E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS19005 da57c10596a62dbdc8e660b304b6312b 281 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 262 4.3E-68 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted LK06_RS19005 da57c10596a62dbdc8e660b304b6312b 281 SUPERFAMILY SSF51679 17 275 1.09E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS09940 dec77a7910a88f290eadbd25fb2159d5 397 Pfam PF01757 Acyltransferase family 50 352 4.0E-25 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 LK06_RS07285 d70f1646b1cb89bd48f871cd7c5e80ab 242 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 16 240 1.2E-68 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase LK06_RS07285 d70f1646b1cb89bd48f871cd7c5e80ab 242 Gene3D G3DSA:3.60.140.10 8 241 3.2E-83 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase LK06_RS07285 d70f1646b1cb89bd48f871cd7c5e80ab 242 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 21 241 1.0E-49 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase LK06_RS07285 d70f1646b1cb89bd48f871cd7c5e80ab 242 SUPERFAMILY SSF64438 9 242 3.48E-73 T 06-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic LK06_RS16170 6a372269475f0e9e0cfbd490cb489a3e 414 Pfam PF04434 SWIM zinc finger 136 157 2.4E-5 T 06-07-2017 IPR007527 Zinc finger, SWIM-type GO:0008270 LK06_RS14285 49c695b632defe103c51cb427bff88b4 336 Pfam PF06259 Alpha/beta hydrolase 93 258 8.7E-34 T 06-07-2017 IPR010427 Protein of unknown function DUF1023 LK06_RS11240 8d4a540629c51d148a6fcbb2fd6512cf 201 Pfam PF09438 Domain of unknown function (DUF2017) 9 198 1.3E-59 T 06-07-2017 IPR018561 Domain of unknown function DUF2017 LK06_RS05460 54d75ab00528c6e9a22c8819ba604d8c 257 Pfam PF01522 Polysaccharide deacetylase 56 186 7.5E-31 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS05460 54d75ab00528c6e9a22c8819ba604d8c 257 SUPERFAMILY SSF88713 20 191 3.24E-39 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS05460 54d75ab00528c6e9a22c8819ba604d8c 257 Gene3D G3DSA:3.20.20.370 53 186 1.3E-30 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS28225 e3f3e1cb2ed5827d3774a967e5abcbd2 384 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 51 354 1.9E-89 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter LK06_RS28225 e3f3e1cb2ed5827d3774a967e5abcbd2 384 PIRSF PIRSF026166 38 372 1.1E-124 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter LK06_RS05610 b3f28563fdc5c316fb12e1576937be8e 346 Gene3D G3DSA:1.20.144.10 49 231 2.5E-19 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS05610 b3f28563fdc5c316fb12e1576937be8e 346 SUPERFAMILY SSF48317 36 248 2.09E-28 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS05610 b3f28563fdc5c316fb12e1576937be8e 346 SMART SM00014 115 230 3.7E-6 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS05610 b3f28563fdc5c316fb12e1576937be8e 346 Pfam PF01569 PAP2 superfamily 117 232 4.9E-18 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS03065 13271665fc0275a698d02d39dbe6c396 150 SUPERFAMILY SSF54637 10 145 6.75E-18 T 06-07-2017 IPR029069 HotDog domain LK06_RS03065 13271665fc0275a698d02d39dbe6c396 150 Pfam PF14539 Domain of unknown function (DUF4442) 11 145 7.3E-25 T 06-07-2017 IPR027961 Protein of unknown function DUF4442 LK06_RS03065 13271665fc0275a698d02d39dbe6c396 150 Gene3D G3DSA:3.10.129.10 7 147 4.6E-37 T 06-07-2017 IPR029069 HotDog domain LK06_RS31785 1a405dfff6e82492f43248c18ea0bead 332 PIRSF PIRSF009283 1 332 3.7E-91 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 LK06_RS31785 1a405dfff6e82492f43248c18ea0bead 332 Gene3D G3DSA:3.10.180.10 2 103 1.3E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS31785 1a405dfff6e82492f43248c18ea0bead 332 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 5 329 1.0E-85 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 LK06_RS31785 1a405dfff6e82492f43248c18ea0bead 332 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 289 2.2E-12 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS31785 1a405dfff6e82492f43248c18ea0bead 332 Gene3D G3DSA:3.10.180.10 139 332 1.2E-55 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS31785 1a405dfff6e82492f43248c18ea0bead 332 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 1 104 1.7E-7 T 06-07-2017 LK06_RS31785 1a405dfff6e82492f43248c18ea0bead 332 SUPERFAMILY SSF54593 1 322 5.94E-59 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS05165 57b2346f1693065b8ef143ee122e2b2d 327 Gene3D G3DSA:3.20.20.100 9 321 1.7E-87 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS05165 57b2346f1693065b8ef143ee122e2b2d 327 SUPERFAMILY SSF51430 1 316 1.2E-87 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS05165 57b2346f1693065b8ef143ee122e2b2d 327 Pfam PF00248 Aldo/keto reductase family 15 312 1.2E-58 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS05800 3e7f81198fb36430efbf5fe32c9f77ca 427 PIRSF PIRSF033563 14 427 6.5E-122 T 06-07-2017 IPR008323 Uncharacterised conserved protein UCP033563 LK06_RS05800 3e7f81198fb36430efbf5fe32c9f77ca 427 Pfam PF06245 Protein of unknown function (DUF1015) 17 423 4.7E-115 T 06-07-2017 IPR008323 Uncharacterised conserved protein UCP033563 LK06_RS08025 d00359faddb4cddec29895acc29c6304 122 SUPERFAMILY SSF52833 2 117 4.48E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS08025 d00359faddb4cddec29895acc29c6304 122 Pfam PF03960 ArsC family 54 115 1.4E-8 T 06-07-2017 IPR006660 Arsenate reductase-like LK06_RS08025 d00359faddb4cddec29895acc29c6304 122 Gene3D G3DSA:3.40.30.10 2 118 1.2E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS06810 6bd1eb46bc1a47d41267fb1cb82dd795 214 SUPERFAMILY SSF52833 47 183 3.73E-6 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS06810 6bd1eb46bc1a47d41267fb1cb82dd795 214 Pfam PF05988 Bacterial protein of unknown function (DUF899) 3 212 8.5E-77 T 06-07-2017 IPR010296 Protein of unknown function DUF899, thioredoxin-like LK06_RS12385 a90a79ae7afa3ef30368b047e6b12a67 533 Pfam PF01235 Sodium:alanine symporter family 98 517 8.1E-125 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 LK06_RS12385 a90a79ae7afa3ef30368b047e6b12a67 533 PRINTS PR00175 Sodium/alanine symporter signature 273 292 2.7E-43 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 LK06_RS12385 a90a79ae7afa3ef30368b047e6b12a67 533 PRINTS PR00175 Sodium/alanine symporter signature 134 156 2.7E-43 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 LK06_RS12385 a90a79ae7afa3ef30368b047e6b12a67 533 PRINTS PR00175 Sodium/alanine symporter signature 479 499 2.7E-43 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 LK06_RS12385 a90a79ae7afa3ef30368b047e6b12a67 533 PRINTS PR00175 Sodium/alanine symporter signature 245 263 2.7E-43 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 LK06_RS12385 a90a79ae7afa3ef30368b047e6b12a67 533 PRINTS PR00175 Sodium/alanine symporter signature 418 440 2.7E-43 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 LK06_RS12385 a90a79ae7afa3ef30368b047e6b12a67 533 PRINTS PR00175 Sodium/alanine symporter signature 363 381 2.7E-43 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 LK06_RS12385 a90a79ae7afa3ef30368b047e6b12a67 533 TIGRFAM TIGR00835 agcS: amino acid carrier protein 62 507 2.0E-113 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 LK06_RS07605 96e270afa1f5170a78078b8bfa31e5b7 456 Gene3D G3DSA:3.90.1150.10 411 436 1.0E-14 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS07605 96e270afa1f5170a78078b8bfa31e5b7 456 Gene3D G3DSA:3.90.1150.10 296 379 1.0E-14 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS07605 96e270afa1f5170a78078b8bfa31e5b7 456 SUPERFAMILY SSF53383 38 439 2.06E-83 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS07605 96e270afa1f5170a78078b8bfa31e5b7 456 Pfam PF00266 Aminotransferase class-V 41 428 9.2E-73 T 06-07-2017 IPR000192 Aminotransferase class V domain LK06_RS07605 96e270afa1f5170a78078b8bfa31e5b7 456 Gene3D G3DSA:3.40.640.10 57 295 6.1E-65 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS11975 50b968f6bce47ff23c5421c61e7c53ce 540 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 410 501 6.5E-14 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain LK06_RS11975 50b968f6bce47ff23c5421c61e7c53ce 540 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 141 301 6.7E-37 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS11975 50b968f6bce47ff23c5421c61e7c53ce 540 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 141 302 2.7E-41 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS08655 d1d3d8cad9611a75ac35537f21eb2eca 193 Pfam PF01169 Uncharacterized protein family UPF0016 10 79 9.5E-15 T 06-07-2017 IPR001727 Gdt1 family GO:0032472 LK06_RS08655 d1d3d8cad9611a75ac35537f21eb2eca 193 Pfam PF01169 Uncharacterized protein family UPF0016 110 183 1.4E-18 T 06-07-2017 IPR001727 Gdt1 family GO:0032472 LK06_RS24610 57979cf7f8da45a2e0e60d4dc7c693f0 134 Pfam PF13828 Domain of unknown function (DUF4190) 58 122 2.3E-10 T 06-07-2017 IPR025241 Domain of unknown function DUF4190 LK06_RS21125 3bc15ba96e97d8544ae195685fc5b06b 277 SUPERFAMILY SSF53335 75 213 7.93E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS21125 3bc15ba96e97d8544ae195685fc5b06b 277 Pfam PF13578 Methyltransferase domain 108 209 2.6E-19 T 06-07-2017 LK06_RS21125 3bc15ba96e97d8544ae195685fc5b06b 277 Gene3D G3DSA:3.40.50.150 68 215 1.1E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS03085 09024dc0e04e9f200c81ae00fbe25344 256 Pfam PF09335 SNARE associated Golgi protein 101 218 6.3E-24 T 06-07-2017 IPR032816 SNARE associated Golgi protein LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 5.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 5.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 5.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 SUPERFAMILY SSF52172 2 123 3.13E-11 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 SUPERFAMILY SSF46894 131 200 1.63E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 Gene3D G3DSA:1.10.10.10 120 201 3.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 SMART SM00421 138 195 9.1E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 194 8.2E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 Pfam PF00072 Response regulator receiver domain 4 116 3.0E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 SMART SM00448 2 115 0.0075 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS01025 1fec2accc41838e3db508ddc8b9895a1 201 Gene3D G3DSA:3.40.50.2300 2 119 4.5E-11 T 06-07-2017 LK06_RS16240 e26720ef4e0e40615d5ae431307936c5 310 PIRSF PIRSF001500 1 278 1.2E-61 T 06-07-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 LK06_RS16240 e26720ef4e0e40615d5ae431307936c5 310 Gene3D G3DSA:3.40.190.10 93 170 5.5E-22 T 06-07-2017 LK06_RS16240 e26720ef4e0e40615d5ae431307936c5 310 Pfam PF01842 ACT domain 203 258 7.9E-9 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 LK06_RS16240 e26720ef4e0e40615d5ae431307936c5 310 Gene3D G3DSA:3.40.190.10 4 92 2.1E-24 T 06-07-2017 LK06_RS16240 e26720ef4e0e40615d5ae431307936c5 310 SUPERFAMILY SSF55021 177 275 4.93E-22 T 06-07-2017 LK06_RS16240 e26720ef4e0e40615d5ae431307936c5 310 Gene3D G3DSA:3.30.70.260 189 276 3.0E-27 T 06-07-2017 LK06_RS16240 e26720ef4e0e40615d5ae431307936c5 310 SUPERFAMILY SSF53850 5 187 7.73E-51 T 06-07-2017 LK06_RS16240 e26720ef4e0e40615d5ae431307936c5 310 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 158 180 - T 06-07-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 LK06_RS16240 e26720ef4e0e40615d5ae431307936c5 310 Pfam PF00800 Prephenate dehydratase 6 183 3.3E-48 T 06-07-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 LK06_RS08325 07376118e5bce8ec84048562b67d6624 448 Gene3D G3DSA:1.20.1250.20 47 211 3.2E-29 T 06-07-2017 LK06_RS08325 07376118e5bce8ec84048562b67d6624 448 Gene3D G3DSA:1.20.1250.20 252 441 4.7E-6 T 06-07-2017 LK06_RS08325 07376118e5bce8ec84048562b67d6624 448 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 33 430 4.7E-94 T 06-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 LK06_RS08325 07376118e5bce8ec84048562b67d6624 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 88 104 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LK06_RS08325 07376118e5bce8ec84048562b67d6624 448 SUPERFAMILY SSF103473 20 442 5.89E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08325 07376118e5bce8ec84048562b67d6624 448 Pfam PF07690 Major Facilitator Superfamily 47 396 6.7E-38 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS00250 4cbc595e5dd7658d11ec520bca627e0e 134 Gene3D G3DSA:2.60.40.790 26 132 5.4E-25 T 06-07-2017 IPR008978 HSP20-like chaperone LK06_RS00250 4cbc595e5dd7658d11ec520bca627e0e 134 SUPERFAMILY SSF49764 11 130 9.42E-27 T 06-07-2017 IPR008978 HSP20-like chaperone LK06_RS00250 4cbc595e5dd7658d11ec520bca627e0e 134 Pfam PF00011 Hsp20/alpha crystallin family 38 130 3.6E-20 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain LK06_RS30125 d26df9e86c032498411da9650819f026 387 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 3 378 7.2E-147 T 06-07-2017 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB LK06_RS30125 d26df9e86c032498411da9650819f026 387 Gene3D G3DSA:3.90.550.10 39 245 3.5E-18 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS30125 d26df9e86c032498411da9650819f026 387 SUPERFAMILY SSF53448 29 248 2.2E-34 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS30125 d26df9e86c032498411da9650819f026 387 Pfam PF13641 Glycosyltransferase like family 2 38 247 1.9E-20 T 06-07-2017 LK06_RS24635 c5f9eb6b0ed8a86fbbcc48ecbdd75f61 309 SUPERFAMILY SSF161098 25 303 2.22E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24635 c5f9eb6b0ed8a86fbbcc48ecbdd75f61 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 296 2.9E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24635 c5f9eb6b0ed8a86fbbcc48ecbdd75f61 309 Gene3D G3DSA:1.10.3720.10 20 300 1.6E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS06660 a2b14552820bcb191dce50cecaabf7d2 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 237 250 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 LK06_RS06660 a2b14552820bcb191dce50cecaabf7d2 303 Gene3D G3DSA:3.40.1190.20 2 296 1.9E-66 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS06660 a2b14552820bcb191dce50cecaabf7d2 303 Pfam PF00294 pfkB family carbohydrate kinase 2 295 2.0E-45 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB LK06_RS06660 a2b14552820bcb191dce50cecaabf7d2 303 SUPERFAMILY SSF53613 2 296 1.56E-63 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS15630 ef4b8388ae013522b13c43e714a750a2 296 Pfam PF01694 Rhomboid family 129 263 7.6E-37 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 LK06_RS15630 ef4b8388ae013522b13c43e714a750a2 296 Gene3D G3DSA:1.20.1540.10 85 261 1.2E-39 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 LK06_RS15630 ef4b8388ae013522b13c43e714a750a2 296 SUPERFAMILY SSF144091 83 268 5.75E-44 T 06-07-2017 LK06_RS01140 b3ab07bee9da1a5f96905346a1c51792 322 Gene3D G3DSA:3.20.20.100 9 317 9.3E-109 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS01140 b3ab07bee9da1a5f96905346a1c51792 322 PRINTS PR00069 Aldo-keto reductase signature 113 131 2.7E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS01140 b3ab07bee9da1a5f96905346a1c51792 322 PRINTS PR00069 Aldo-keto reductase signature 144 161 2.7E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS01140 b3ab07bee9da1a5f96905346a1c51792 322 PRINTS PR00069 Aldo-keto reductase signature 47 71 2.7E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LK06_RS01140 b3ab07bee9da1a5f96905346a1c51792 322 SUPERFAMILY SSF51430 1 315 2.75E-107 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS01140 b3ab07bee9da1a5f96905346a1c51792 322 Pfam PF00248 Aldo/keto reductase family 15 312 4.3E-79 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS12740 c9048ccdc9f4f090e4c9d193d7f22621 399 Pfam PF03888 MucB/RseB N-terminal domain 187 273 1.9E-5 T 06-07-2017 IPR033434 MucB/RseB, N-terminal LK06_RS12740 c9048ccdc9f4f090e4c9d193d7f22621 399 Gene3D G3DSA:2.50.20.10 145 291 1.9E-17 T 06-07-2017 LK06_RS12740 c9048ccdc9f4f090e4c9d193d7f22621 399 SUPERFAMILY SSF89392 133 289 5.49E-17 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX LK06_RS15995 0ff128d6d33d17aba4c0f7b797643d09 190 Pfam PF00436 Single-strand binding protein family 7 107 3.7E-30 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 LK06_RS15995 0ff128d6d33d17aba4c0f7b797643d09 190 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 123 4.4E-29 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 LK06_RS15995 0ff128d6d33d17aba4c0f7b797643d09 190 Gene3D G3DSA:2.40.50.140 4 116 3.2E-41 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS15995 0ff128d6d33d17aba4c0f7b797643d09 190 SUPERFAMILY SSF50249 6 190 1.93E-45 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS15995 0ff128d6d33d17aba4c0f7b797643d09 190 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.182 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 LK06_RS07295 f84bb969040e89e41fbf0bccecb5afb3 260 Pfam PF08478 POTRA domain, FtsQ-type 54 122 3.7E-17 T 06-07-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type LK06_RS07295 f84bb969040e89e41fbf0bccecb5afb3 260 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 23 258 18.661 T 06-07-2017 IPR026579 Cell division protein FtsQ GO:0090529 LK06_RS03725 97e639f597f2b9bd9fc79f14b0807926 396 SUPERFAMILY SSF53901 4 229 1.6E-31 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03725 97e639f597f2b9bd9fc79f14b0807926 396 Gene3D G3DSA:3.40.47.10 193 220 1.3E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03725 97e639f597f2b9bd9fc79f14b0807926 396 Gene3D G3DSA:3.40.47.10 9 112 1.3E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03725 97e639f597f2b9bd9fc79f14b0807926 396 SUPERFAMILY SSF53901 276 385 9.6E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03725 97e639f597f2b9bd9fc79f14b0807926 396 PIRSF PIRSF000429 1 396 2.7E-33 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS03725 97e639f597f2b9bd9fc79f14b0807926 396 Pfam PF00108 Thiolase, N-terminal domain 23 111 2.3E-7 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 LK06_RS03725 97e639f597f2b9bd9fc79f14b0807926 396 Gene3D G3DSA:3.40.47.10 143 182 6.9E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS03725 97e639f597f2b9bd9fc79f14b0807926 396 Gene3D G3DSA:3.40.47.10 257 394 6.9E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS17695 513eb0f65877f8a2200360bd7faae486 307 SUPERFAMILY SSF46785 21 93 3.03E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17695 513eb0f65877f8a2200360bd7faae486 307 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 80 1.9E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17695 513eb0f65877f8a2200360bd7faae486 307 Gene3D G3DSA:1.10.10.10 28 93 2.3E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17695 513eb0f65877f8a2200360bd7faae486 307 SMART SM00345 29 89 1.3E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17695 513eb0f65877f8a2200360bd7faae486 307 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 1.1E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17695 513eb0f65877f8a2200360bd7faae486 307 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 1.1E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS17035 c7f370d372aedd1723428ed3336ccb39 151 Pfam PF03724 META domain 37 143 4.7E-25 T 06-07-2017 IPR005184 Domain of unknown function DUF306, Meta/HslJ LK06_RS20530 c4335f4164a73788edcdcc47f2475fd8 145 SUPERFAMILY SSF54593 9 128 6.04E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS20530 c4335f4164a73788edcdcc47f2475fd8 145 Gene3D G3DSA:3.10.180.10 13 124 8.0E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS17315 a2825f4ab466f667aee746ed90393a20 458 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 342 9.4E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS17315 a2825f4ab466f667aee746ed90393a20 458 SUPERFAMILY SSF51905 173 356 1.87E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS17315 a2825f4ab466f667aee746ed90393a20 458 Gene3D G3DSA:3.50.50.60 5 122 2.7E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS17315 a2825f4ab466f667aee746ed90393a20 458 Gene3D G3DSA:3.50.50.60 278 356 2.7E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS17315 a2825f4ab466f667aee746ed90393a20 458 SUPERFAMILY SSF51905 6 224 1.79E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS17315 a2825f4ab466f667aee746ed90393a20 458 Gene3D G3DSA:3.50.50.60 123 277 2.1E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS17315 a2825f4ab466f667aee746ed90393a20 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.8E-10 T 06-07-2017 LK06_RS17315 a2825f4ab466f667aee746ed90393a20 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 6.8E-10 T 06-07-2017 LK06_RS17315 a2825f4ab466f667aee746ed90393a20 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 6.8E-10 T 06-07-2017 LK06_RS08410 a9aa7a3fbd39849f41b1857918f4dc36 260 Pfam PF03883 Protein of unknown function (DUF328) 2 241 2.1E-40 T 06-07-2017 IPR005583 Peroxide stress protein YaaA LK06_RS08410 a9aa7a3fbd39849f41b1857918f4dc36 260 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 257 20.806 T 06-07-2017 IPR005583 Peroxide stress protein YaaA LK06_RS05840 c3cb4ad7896a40b753ef4a87c9e1668c 431 Pfam PF01609 Transposase DDE domain 170 387 1.3E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS05840 c3cb4ad7896a40b753ef4a87c9e1668c 431 Pfam PF13808 DDE_Tnp_1-associated 37 125 5.3E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS27085 440301d6b8dd5a49bb087e73bd41e197 160 Pfam PF04306 Protein of unknown function (DUF456) 21 156 5.2E-27 T 06-07-2017 IPR007403 Protein of unknown function DUF456 LK06_RS19220 d6d848cdf0b8bb44d88514c713006fd9 195 SMART SM00860 37 161 2.8E-4 T 06-07-2017 IPR018958 SMI1/KNR4-like domain LK06_RS19220 d6d848cdf0b8bb44d88514c713006fd9 195 SUPERFAMILY SSF160631 28 168 3.01E-7 T 06-07-2017 LK06_RS23400 88d31f7c6a6bb82bab2cdc88af6f8809 295 Pfam PF12679 ABC-2 family transporter protein 101 295 1.2E-9 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 LK06_RS00045 f429b5cb221a7d996d9dd7eb18a1c2ba 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 285 1.8E-36 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 LK06_RS19520 a7606cb851331599c10740cbed921027 295 SUPERFAMILY SSF81301 18 154 6.54E-9 T 06-07-2017 LK06_RS19520 a7606cb851331599c10740cbed921027 295 Gene3D G3DSA:3.30.460.10 18 71 2.2E-5 T 06-07-2017 LK06_RS26310 9696c9c3b6aad19a8bdb4d05414a5708 355 Pfam PF00155 Aminotransferase class I and II 44 345 6.1E-43 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS26310 9696c9c3b6aad19a8bdb4d05414a5708 355 Gene3D G3DSA:3.90.1150.10 255 350 2.6E-19 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS26310 9696c9c3b6aad19a8bdb4d05414a5708 355 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 209 218 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 LK06_RS26310 9696c9c3b6aad19a8bdb4d05414a5708 355 SUPERFAMILY SSF53383 18 349 3.48E-69 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS26310 9696c9c3b6aad19a8bdb4d05414a5708 355 Gene3D G3DSA:3.40.640.10 35 254 1.0E-50 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS29775 efe5e6c3ac7fdf19953ea6fb881cd4c7 124 Pfam PF01937 Protein of unknown function DUF89 6 89 8.7E-13 T 06-07-2017 IPR002791 Domain of unknown function DUF89 LK06_RS29775 efe5e6c3ac7fdf19953ea6fb881cd4c7 124 SUPERFAMILY SSF111321 6 85 1.44E-5 T 06-07-2017 IPR002791 Domain of unknown function DUF89 LK06_RS20115 618b830128d98d69ae2b9f9eb6b392f1 102 SMART SM00883 9 100 1.3E-52 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS20115 618b830128d98d69ae2b9f9eb6b392f1 102 ProSitePatterns PS00681 Chaperonins cpn10 signature. 10 34 - T 06-07-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 LK06_RS20115 618b830128d98d69ae2b9f9eb6b392f1 102 Hamap MF_00580 10 kDa chaperonin [groS]. 9 101 25.823 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS20115 618b830128d98d69ae2b9f9eb6b392f1 102 Pfam PF00166 Chaperonin 10 Kd subunit 10 100 4.5E-33 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS20115 618b830128d98d69ae2b9f9eb6b392f1 102 Gene3D G3DSA:2.30.33.40 10 101 3.5E-37 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS20115 618b830128d98d69ae2b9f9eb6b392f1 102 PRINTS PR00297 10kDa chaperonin signature 10 25 2.8E-31 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS20115 618b830128d98d69ae2b9f9eb6b392f1 102 PRINTS PR00297 10kDa chaperonin signature 87 100 2.8E-31 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS20115 618b830128d98d69ae2b9f9eb6b392f1 102 PRINTS PR00297 10kDa chaperonin signature 32 53 2.8E-31 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS20115 618b830128d98d69ae2b9f9eb6b392f1 102 PRINTS PR00297 10kDa chaperonin signature 66 78 2.8E-31 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS20115 618b830128d98d69ae2b9f9eb6b392f1 102 SUPERFAMILY SSF50129 9 101 4.36E-33 T 06-07-2017 IPR011032 GroES-like LK06_RS25220 6976e0c0f83ced07939e9b1727252e62 219 SUPERFAMILY SSF53254 4 199 2.62E-43 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS25220 6976e0c0f83ced07939e9b1727252e62 219 Gene3D G3DSA:3.40.50.1240 4 204 2.4E-45 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS25220 6976e0c0f83ced07939e9b1727252e62 219 SMART SM00855 6 166 7.9E-18 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS25220 6976e0c0f83ced07939e9b1727252e62 219 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 LK06_RS25220 6976e0c0f83ced07939e9b1727252e62 219 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 198 4.7E-36 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS21940 ca21a0a0eac6e85cfd369b0715c8bf10 246 PIRSF PIRSF006648 1 244 5.4E-19 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS21940 ca21a0a0eac6e85cfd369b0715c8bf10 246 Pfam PF12698 ABC-2 family transporter protein 50 232 9.2E-14 T 06-07-2017 LK06_RS15975 268e24d66e9e3564f376891573aad7d4 343 Gene3D G3DSA:3.20.20.10 26 172 3.1E-14 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS15975 268e24d66e9e3564f376891573aad7d4 343 SUPERFAMILY SSF51419 9 176 8.72E-16 T 06-07-2017 IPR029066 PLP-binding barrel LK06_RS15975 268e24d66e9e3564f376891573aad7d4 343 Pfam PF01168 Alanine racemase, N-terminal domain 7 153 2.0E-14 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LK06_RS28865 3af1a2ff6c5cb76d244dcdcde1068c3d 235 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 29 217 5.9E-26 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LK06_RS28865 3af1a2ff6c5cb76d244dcdcde1068c3d 235 SUPERFAMILY SSF52518 33 229 3.21E-47 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS28865 3af1a2ff6c5cb76d244dcdcde1068c3d 235 Gene3D G3DSA:3.40.50.970 32 229 4.7E-47 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS13440 4602c76e3c4396dfeba3df1c85bac4a9 314 Gene3D G3DSA:3.40.50.1000 136 280 4.0E-50 T 06-07-2017 IPR023214 HAD-like domain LK06_RS13440 4602c76e3c4396dfeba3df1c85bac4a9 314 SUPERFAMILY SSF56784 62 275 1.01E-29 T 06-07-2017 IPR023214 HAD-like domain LK06_RS13440 4602c76e3c4396dfeba3df1c85bac4a9 314 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 63 253 2.1E-16 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 LK06_RS13440 4602c76e3c4396dfeba3df1c85bac4a9 314 Pfam PF12710 haloacid dehalogenase-like hydrolase 64 250 1.9E-29 T 06-07-2017 LK06_RS13440 4602c76e3c4396dfeba3df1c85bac4a9 314 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 63 264 1.6E-55 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial LK06_RS22815 270228de23834527742ec208e061784f 222 Pfam PF09335 SNARE associated Golgi protein 46 176 1.9E-19 T 06-07-2017 IPR032816 SNARE associated Golgi protein LK06_RS16630 b2daf4fa0f19199145bfbd80c42d866b 762 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 110 267 1.6E-32 T 06-07-2017 LK06_RS09815 17cfdcb134a62c79803bbe4e55cc383b 340 SUPERFAMILY SSF56796 3 333 1.13E-55 T 06-07-2017 LK06_RS09815 17cfdcb134a62c79803bbe4e55cc383b 340 Gene3D G3DSA:3.40.50.1970 3 144 2.3E-26 T 06-07-2017 LK06_RS09815 17cfdcb134a62c79803bbe4e55cc383b 340 Pfam PF13685 Iron-containing alcohol dehydrogenase 3 257 4.5E-56 T 06-07-2017 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295 LK06_RS09815 17cfdcb134a62c79803bbe4e55cc383b 340 Gene3D G3DSA:1.20.1090.10 146 326 3.6E-59 T 06-07-2017 LK06_RS09815 17cfdcb134a62c79803bbe4e55cc383b 340 PIRSF PIRSF000112 1 339 8.3E-91 T 06-07-2017 LK06_RS08335 86eb16b470f87a276df7b001778f1348 408 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 62 291 2.5E-34 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 LK06_RS08335 86eb16b470f87a276df7b001778f1348 408 Gene3D G3DSA:3.40.710.10 61 311 4.2E-68 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS08335 86eb16b470f87a276df7b001778f1348 408 SUPERFAMILY SSF56601 22 311 4.12E-47 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS27400 49c6a72bac1c3459be2f11eeb25583b5 132 SUPERFAMILY SSF49472 5 132 1.96E-28 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 LK06_RS27400 49c6a72bac1c3459be2f11eeb25583b5 132 ProSitePatterns PS00768 Transthyretin signature 1. 12 27 - T 06-07-2017 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 LK06_RS27400 49c6a72bac1c3459be2f11eeb25583b5 132 Pfam PF00576 HIUase/Transthyretin family 9 131 2.6E-35 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 LK06_RS27400 49c6a72bac1c3459be2f11eeb25583b5 132 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 7 132 4.9E-31 T 06-07-2017 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394 LK06_RS27400 49c6a72bac1c3459be2f11eeb25583b5 132 Gene3D G3DSA:2.60.40.180 6 132 3.1E-35 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 21 371 8.7E-108 T 06-07-2017 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 Gene3D G3DSA:1.10.275.10 20 110 2.9E-28 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 Pfam PF00206 Lyase 26 321 4.6E-34 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 Gene3D G3DSA:1.20.200.10 111 391 4.3E-90 T 06-07-2017 LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 SMART SM00998 386 465 8.1E-11 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 Gene3D G3DSA:1.10.40.30 392 465 2.3E-18 T 06-07-2017 LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 SUPERFAMILY SSF48557 25 467 4.24E-87 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 Pfam PF10397 Adenylosuccinate lyase C-terminus 387 464 1.2E-10 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 PRINTS PR00149 Fumarate lyase superfamily signature 298 314 4.5E-17 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 PRINTS PR00149 Fumarate lyase superfamily signature 108 126 4.5E-17 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 PRINTS PR00149 Fumarate lyase superfamily signature 253 280 4.5E-17 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS27280 032acd0803755801dc7e0ea1baaf38bd 472 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 4.5E-17 T 06-07-2017 IPR000362 Fumarate lyase family LK06_RS07875 413d93e7c1c4b4a4551c916804954095 353 Gene3D G3DSA:1.20.1260.10 50 115 1.8E-4 T 06-07-2017 IPR012347 Ferritin-related LK06_RS07875 413d93e7c1c4b4a4551c916804954095 353 Pfam PF12902 Ferritin-like 52 246 9.8E-50 T 06-07-2017 LK06_RS26015 b0457e6229c69f3922dd87742e53f933 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 1.6E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS26015 b0457e6229c69f3922dd87742e53f933 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 1.6E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS26015 b0457e6229c69f3922dd87742e53f933 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 1.6E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS26015 b0457e6229c69f3922dd87742e53f933 154 Gene3D G3DSA:1.10.10.10 16 150 2.4E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26015 b0457e6229c69f3922dd87742e53f933 154 SUPERFAMILY SSF46785 16 149 9.25E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS26015 b0457e6229c69f3922dd87742e53f933 154 Pfam PF01047 MarR family 45 99 8.9E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS26015 b0457e6229c69f3922dd87742e53f933 154 SMART SM00347 36 136 6.7E-22 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS30735 74f63481c8a651a57fdac7705607d962 130 Gene3D G3DSA:3.10.180.10 3 129 1.2E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30735 74f63481c8a651a57fdac7705607d962 130 SUPERFAMILY SSF54593 2 128 3.09E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30735 74f63481c8a651a57fdac7705607d962 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 124 3.3E-14 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LK06_RS28515 473227d044949c2f4d2cdb6891aeee48 281 Pfam PF14378 PAP2 superfamily 56 235 1.6E-39 T 06-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 LK06_RS31500 c7b4e1812f2292d8042f7203bda3e43b 107 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 18 96 3.1E-26 T 06-07-2017 IPR009359 Phenylacetic acid degradation B LK06_RS31500 c7b4e1812f2292d8042f7203bda3e43b 107 Pfam PF06243 Phenylacetic acid degradation B 18 97 6.2E-28 T 06-07-2017 IPR009359 Phenylacetic acid degradation B LK06_RS17665 5221b1203e948bc1c2cabd174647dfcf 191 SUPERFAMILY SSF50814 7 165 1.13E-41 T 06-07-2017 IPR011038 Calycin-like LK06_RS17665 5221b1203e948bc1c2cabd174647dfcf 191 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 4 166 31.91 T 06-07-2017 IPR022939 Uncharacterised protein family UPF0678 LK06_RS17665 5221b1203e948bc1c2cabd174647dfcf 191 Pfam PF08768 Domain of unknown function (DUF1794) 12 164 7.5E-48 T 06-07-2017 IPR014878 Domain of unknown function DUF1794 LK06_RS32000 cc184a5317e54863eb3ab5d274bdc7fb 180 SUPERFAMILY SSF52540 2 126 9.08E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32000 cc184a5317e54863eb3ab5d274bdc7fb 180 Gene3D G3DSA:3.40.50.300 2 114 4.8E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21680 472ff49471d1cad73a0bd4a3c3bb5adf 128 Pfam PF14206 Cysteine-rich CPCC 5 79 2.5E-34 T 06-07-2017 IPR025983 Cysteine-rich CPCC domain LK06_RS30910 31828c11919c06276f59379d86c5f7c6 111 Pfam PF04343 Protein of unknown function, DUF488 2 109 5.6E-29 T 06-07-2017 IPR007438 Protein of unknown function DUF488 LK06_RS21405 053ff5474fefb809bdb4e0107e7bc815 174 Gene3D G3DSA:1.10.10.10 1 87 9.9E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21405 053ff5474fefb809bdb4e0107e7bc815 174 SUPERFAMILY SSF46785 3 167 4.17E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21405 053ff5474fefb809bdb4e0107e7bc815 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 6.3E-14 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal LK06_RS21970 278ff859f4daef5373d2ddae05fe98e2 375 SUPERFAMILY SSF53383 17 375 2.15E-79 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS21970 278ff859f4daef5373d2ddae05fe98e2 375 Gene3D G3DSA:3.40.640.10 55 253 9.5E-42 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS21970 278ff859f4daef5373d2ddae05fe98e2 375 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 233 246 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 LK06_RS21970 278ff859f4daef5373d2ddae05fe98e2 375 Pfam PF00155 Aminotransferase class I and II 42 375 2.0E-38 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS21970 278ff859f4daef5373d2ddae05fe98e2 375 Gene3D G3DSA:3.90.1150.10 254 375 1.8E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS21970 278ff859f4daef5373d2ddae05fe98e2 375 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 20 375 3.8E-181 T 06-07-2017 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria LK06_RS16875 f623911125e374cae21aa06d9e344d68 268 SUPERFAMILY SSF56112 32 239 5.83E-16 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS16875 f623911125e374cae21aa06d9e344d68 268 Gene3D G3DSA:3.90.1200.10 115 247 1.2E-7 T 06-07-2017 LK06_RS23765 e708579c82e4e04263f66fb6052ffa0f 276 Pfam PF14581 SseB protein C-terminal domain 135 239 1.2E-15 T 06-07-2017 IPR027945 SseB protein, C-terminal LK06_RS24185 359848c1eb8ae91eb0a08d6f9161ae73 197 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 39.274 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 LK06_RS24185 359848c1eb8ae91eb0a08d6f9161ae73 197 Gene3D G3DSA:3.20.19.10 1 185 5.5E-40 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel LK06_RS24185 359848c1eb8ae91eb0a08d6f9161ae73 197 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 178 1.7E-56 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 LK06_RS24185 359848c1eb8ae91eb0a08d6f9161ae73 197 Pfam PF00694 Aconitase C-terminal domain 1 117 6.5E-26 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 LK06_RS24185 359848c1eb8ae91eb0a08d6f9161ae73 197 SUPERFAMILY SSF52016 1 179 3.53E-51 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel LK06_RS18805 c5b0f10433f773c6172ca65b48655ac9 158 Pfam PF13581 Histidine kinase-like ATPase domain 11 120 5.7E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS18805 c5b0f10433f773c6172ca65b48655ac9 158 SUPERFAMILY SSF55874 37 127 3.51E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16095 d84572076e9bf233625c76bd59c61e6f 145 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 2.7E-32 T 06-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 LK06_RS06825 a1ae3c8b782b33eef9184e6a40b6b3e1 209 Pfam PF01479 S4 domain 59 105 2.4E-11 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS06825 a1ae3c8b782b33eef9184e6a40b6b3e1 209 Gene3D G3DSA:3.10.290.10 58 149 1.3E-30 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS06825 a1ae3c8b782b33eef9184e6a40b6b3e1 209 SUPERFAMILY SSF55174 59 141 6.28E-24 T 06-07-2017 LK06_RS06825 a1ae3c8b782b33eef9184e6a40b6b3e1 209 SMART SM00363 59 123 7.8E-7 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 LK06_RS18570 a400c36ef484c2339a35caa2898bb662 424 Gene3D G3DSA:1.20.1250.20 8 190 3.5E-19 T 06-07-2017 LK06_RS18570 a400c36ef484c2339a35caa2898bb662 424 Gene3D G3DSA:1.20.1250.20 216 389 6.2E-14 T 06-07-2017 LK06_RS18570 a400c36ef484c2339a35caa2898bb662 424 SUPERFAMILY SSF103473 8 392 2.62E-47 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS18570 a400c36ef484c2339a35caa2898bb662 424 Pfam PF05977 Transmembrane secretion effector 2 388 2.4E-48 T 06-07-2017 IPR010290 Transmembrane secretion effector LK06_RS28475 200e7b69770c0dd6763312186818b7bc 178 Pfam PF04542 Sigma-70 region 2 27 89 7.8E-7 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS28475 200e7b69770c0dd6763312186818b7bc 178 Pfam PF08281 Sigma-70, region 4 120 171 3.5E-11 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS28475 200e7b69770c0dd6763312186818b7bc 178 SUPERFAMILY SSF88659 112 175 3.74E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS28475 200e7b69770c0dd6763312186818b7bc 178 Gene3D G3DSA:1.10.1740.10 22 97 3.3E-11 T 06-07-2017 LK06_RS28475 200e7b69770c0dd6763312186818b7bc 178 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 175 8.8E-13 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS28475 200e7b69770c0dd6763312186818b7bc 178 SUPERFAMILY SSF88946 22 106 1.06E-11 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS28475 200e7b69770c0dd6763312186818b7bc 178 Gene3D G3DSA:1.10.10.10 116 175 1.6E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11935 51981bffa8ebcf79fb4fa13719430e70 251 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 11 247 4.6E-81 T 06-07-2017 IPR017523 Conserved hypothetical protein CHP03089 LK06_RS11935 51981bffa8ebcf79fb4fa13719430e70 251 Gene3D G3DSA:3.40.50.980 7 90 6.0E-7 T 06-07-2017 LK06_RS11935 51981bffa8ebcf79fb4fa13719430e70 251 Gene3D G3DSA:3.40.50.980 191 249 3.6E-4 T 06-07-2017 LK06_RS11935 51981bffa8ebcf79fb4fa13719430e70 251 Pfam PF00501 AMP-binding enzyme 18 90 2.9E-6 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS11935 51981bffa8ebcf79fb4fa13719430e70 251 SUPERFAMILY SSF56801 5 248 3.01E-20 T 06-07-2017 LK06_RS28325 2c63c6ca5201ac1597962a51efa8614b 254 SUPERFAMILY SSF102215 33 240 8.76E-54 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 LK06_RS28325 2c63c6ca5201ac1597962a51efa8614b 254 Pfam PF02633 Creatinine amidohydrolase 28 239 2.5E-55 T 06-07-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 LK06_RS28325 2c63c6ca5201ac1597962a51efa8614b 254 Gene3D G3DSA:3.40.50.10310 31 239 3.4E-60 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 LK06_RS24270 e0548cdf3e84722be94e8f7e88b661b2 194 Gene3D G3DSA:3.40.50.150 1 186 6.7E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS24270 e0548cdf3e84722be94e8f7e88b661b2 194 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 183 3.4E-42 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS24270 e0548cdf3e84722be94e8f7e88b661b2 194 SUPERFAMILY SSF53335 2 182 1.57E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS24270 e0548cdf3e84722be94e8f7e88b661b2 194 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LK06_RS24270 e0548cdf3e84722be94e8f7e88b661b2 194 Pfam PF03602 Conserved hypothetical protein 95 2 183 2.4E-52 T 06-07-2017 LK06_RS24270 e0548cdf3e84722be94e8f7e88b661b2 194 PIRSF PIRSF004553 1 187 1.1E-50 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 SUPERFAMILY SSF51182 2 374 1.64E-95 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 Gene3D G3DSA:1.10.441.10 136 227 1.9E-17 T 06-07-2017 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 Gene3D G3DSA:1.10.441.10 270 282 1.9E-17 T 06-07-2017 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 Gene3D G3DSA:2.60.120.10 6 135 3.9E-58 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 Gene3D G3DSA:2.60.120.10 234 269 3.9E-58 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 2 375 3.0E-75 T 06-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 PIRSF PIRSF001480 1 382 1.0E-92 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 PRINTS PR00714 Phosphomannose isomerase type I signature 76 97 1.6E-61 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 PRINTS PR00714 Phosphomannose isomerase type I signature 251 270 1.6E-61 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 PRINTS PR00714 Phosphomannose isomerase type I signature 270 289 1.6E-61 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 1.6E-61 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 PRINTS PR00714 Phosphomannose isomerase type I signature 121 144 1.6E-61 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 1.6E-61 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 PRINTS PR00714 Phosphomannose isomerase type I signature 216 231 1.6E-61 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 PRINTS PR00714 Phosphomannose isomerase type I signature 232 251 1.6E-61 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 Gene3D G3DSA:2.60.120.10 283 380 1.9E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 Pfam PF01238 Phosphomannose isomerase type I 3 346 2.1E-68 T 06-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS11855 62e35eda8bc92a029ff8c32cac4b6f70 383 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 121 129 - T 06-07-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 LK06_RS02980 888785d883db68f35b19aba6e6a1ff68 135 Pfam PF13380 CoA binding domain 18 131 7.2E-37 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS02980 888785d883db68f35b19aba6e6a1ff68 135 Gene3D G3DSA:3.40.50.720 6 132 1.5E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02980 888785d883db68f35b19aba6e6a1ff68 135 SUPERFAMILY SSF51735 17 133 5.71E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS02980 888785d883db68f35b19aba6e6a1ff68 135 SMART SM00881 12 105 5.6E-20 T 06-07-2017 IPR003781 CoA-binding GO:0048037 LK06_RS08160 69c1dcdae9195c8147471cf4dc1f0f1f 210 Pfam PF03713 Domain of unknown function (DUF305) 45 201 6.3E-47 T 06-07-2017 IPR005183 Domain of unknown function DUF305 LK06_RS08160 69c1dcdae9195c8147471cf4dc1f0f1f 210 Gene3D G3DSA:1.20.1260.10 38 204 2.2E-61 T 06-07-2017 IPR012347 Ferritin-related LK06_RS00220 60fdf85088227e514948d89bafacdcea 137 SUPERFAMILY SSF81333 68 135 4.58E-12 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 LK06_RS00220 60fdf85088227e514948d89bafacdcea 137 Gene3D G3DSA:1.20.120.610 46 136 7.8E-15 T 06-07-2017 LK06_RS00220 60fdf85088227e514948d89bafacdcea 137 Pfam PF00137 ATP synthase subunit C 74 133 8.5E-13 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 LK06_RS00220 60fdf85088227e514948d89bafacdcea 137 PRINTS PR00124 ATP synthase C subunit signature 109 134 1.1E-8 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 LK06_RS00220 60fdf85088227e514948d89bafacdcea 137 PRINTS PR00124 ATP synthase C subunit signature 71 90 1.1E-8 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 LK06_RS27955 6f20ed5ad97f00971df06c0c79c2be42 378 SUPERFAMILY SSF110738 6 374 6.93E-116 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 LK06_RS27955 6f20ed5ad97f00971df06c0c79c2be42 378 Gene3D G3DSA:3.90.1510.10 46 278 5.2E-88 T 06-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 LK06_RS27955 6f20ed5ad97f00971df06c0c79c2be42 378 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 6 374 4.2E-119 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 LK06_RS27955 6f20ed5ad97f00971df06c0c79c2be42 378 Pfam PF02595 Glycerate kinase family 7 374 1.1E-129 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 LK06_RS27955 6f20ed5ad97f00971df06c0c79c2be42 378 PIRSF PIRSF006078 5 378 1.9E-119 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 LK06_RS31110 74810488bf459c83ab7fbfbed4acf13c 287 Gene3D G3DSA:3.90.1200.10 94 265 2.4E-15 T 06-07-2017 LK06_RS31110 74810488bf459c83ab7fbfbed4acf13c 287 SUPERFAMILY SSF56112 31 279 1.75E-41 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS31110 74810488bf459c83ab7fbfbed4acf13c 287 Pfam PF03881 Fructosamine kinase 49 279 2.0E-40 T 06-07-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 LK06_RS31110 74810488bf459c83ab7fbfbed4acf13c 287 PIRSF PIRSF006221 23 286 1.1E-53 T 06-07-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 LK06_RS28955 fe9b4c99043b360b8324c41f19cea626 167 SUPERFAMILY SSF140663 34 154 1.57E-25 T 06-07-2017 IPR023203 TTHA0068-like domain LK06_RS28955 fe9b4c99043b360b8324c41f19cea626 167 Pfam PF03745 Domain of unknown function (DUF309) 54 111 3.4E-18 T 06-07-2017 IPR005500 Protein of unknown function DUF309 LK06_RS28955 fe9b4c99043b360b8324c41f19cea626 167 Gene3D G3DSA:1.10.3450.10 23 155 5.7E-23 T 06-07-2017 IPR023203 TTHA0068-like domain LK06_RS25755 7565dec73c0b5594577aafd1d00ec0c1 263 Gene3D G3DSA:3.40.50.150 85 235 3.5E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25755 7565dec73c0b5594577aafd1d00ec0c1 263 SUPERFAMILY SSF53335 80 203 1.0E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS25755 7565dec73c0b5594577aafd1d00ec0c1 263 Pfam PF08241 Methyltransferase domain 92 187 1.1E-7 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS10645 fe261add62c14effe00b9903cc6206e1 606 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 25 383 1.6E-112 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 LK06_RS10645 fe261add62c14effe00b9903cc6206e1 606 Gene3D G3DSA:3.40.50.1700 409 597 3.6E-20 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 LK06_RS10645 fe261add62c14effe00b9903cc6206e1 606 SUPERFAMILY SSF51445 7 419 2.63E-100 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS10645 fe261add62c14effe00b9903cc6206e1 606 SUPERFAMILY SSF52279 422 599 2.35E-18 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 LK06_RS10645 fe261add62c14effe00b9903cc6206e1 606 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 422 598 3.8E-19 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 LK06_RS10645 fe261add62c14effe00b9903cc6206e1 606 Gene3D G3DSA:3.20.20.300 61 408 4.1E-106 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 LK06_RS17290 e1525482fe9c58debadb639a0e916c16 405 Pfam PF01266 FAD dependent oxidoreductase 12 394 8.9E-60 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS17290 e1525482fe9c58debadb639a0e916c16 405 Gene3D G3DSA:3.30.9.10 96 146 2.9E-7 T 06-07-2017 LK06_RS17290 e1525482fe9c58debadb639a0e916c16 405 Gene3D G3DSA:3.30.9.10 217 233 2.9E-7 T 06-07-2017 LK06_RS17290 e1525482fe9c58debadb639a0e916c16 405 SUPERFAMILY SSF51905 10 308 8.63E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS17290 e1525482fe9c58debadb639a0e916c16 405 Gene3D G3DSA:3.50.50.60 147 216 3.4E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS17290 e1525482fe9c58debadb639a0e916c16 405 Gene3D G3DSA:3.50.50.60 8 93 3.4E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS04240 089a312793be0161277fc8e411b865e4 282 SUPERFAMILY SSF50891 103 277 2.19E-30 T 06-07-2017 IPR029000 Cyclophilin-like domain LK06_RS04240 089a312793be0161277fc8e411b865e4 282 Gene3D G3DSA:2.40.100.10 102 280 8.7E-34 T 06-07-2017 IPR029000 Cyclophilin-like domain LK06_RS04240 089a312793be0161277fc8e411b865e4 282 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 113 278 5.4E-24 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 LK06_RS12830 6b6897b862f5831fa2b24369b2358c23 167 Pfam PF07977 FabA-like domain 24 154 1.1E-21 T 06-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 LK06_RS12830 6b6897b862f5831fa2b24369b2358c23 167 SUPERFAMILY SSF54637 18 162 1.09E-32 T 06-07-2017 IPR029069 HotDog domain LK06_RS12830 6b6897b862f5831fa2b24369b2358c23 167 Gene3D G3DSA:3.10.129.10 11 161 7.2E-42 T 06-07-2017 IPR029069 HotDog domain LK06_RS08300 b8cf6262ebcd4341407356496d727b85 290 Pfam PF03239 Iron permease FTR1 family 1 268 2.4E-71 T 06-07-2017 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 LK06_RS06795 45bd5c80f003a30a52622b5aec94bed1 266 Pfam PF07859 alpha/beta hydrolase fold 41 149 3.2E-8 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 LK06_RS06795 45bd5c80f003a30a52622b5aec94bed1 266 Gene3D G3DSA:3.40.50.1820 20 259 1.4E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS06795 45bd5c80f003a30a52622b5aec94bed1 266 SUPERFAMILY SSF53474 21 230 1.05E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS12880 78bd15f5ecd1b369094cdc79310452c1 312 Pfam PF01435 Peptidase family M48 144 207 1.5E-7 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LK06_RS12880 78bd15f5ecd1b369094cdc79310452c1 312 Gene3D G3DSA:3.30.2010.10 120 198 6.2E-11 T 06-07-2017 LK06_RS17780 b2d7a428ce45497733cbf8c8b74c312b 433 Gene3D G3DSA:3.40.50.2300 46 174 3.3E-20 T 06-07-2017 LK06_RS17780 b2d7a428ce45497733cbf8c8b74c312b 433 SMART SM00448 47 165 4.2E-7 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS17780 b2d7a428ce45497733cbf8c8b74c312b 433 Pfam PF00072 Response regulator receiver domain 50 161 2.6E-9 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS17780 b2d7a428ce45497733cbf8c8b74c312b 433 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 236 431 2.5E-39 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS17780 b2d7a428ce45497733cbf8c8b74c312b 433 SUPERFAMILY SSF52172 46 198 1.21E-16 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS17780 b2d7a428ce45497733cbf8c8b74c312b 433 SMART SM00331 207 431 1.2E-12 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS25345 87e5e16ab70158e82567148381a3f75d 313 Pfam PF06999 Sucrase/ferredoxin-like 17 219 8.6E-19 T 06-07-2017 IPR009737 Thioredoxin-like ferredoxin LK06_RS25345 87e5e16ab70158e82567148381a3f75d 313 PIRSF PIRSF035042 1 311 6.3E-73 T 06-07-2017 IPR010350 Thioredoxin-like ferredoxin, bacteria LK06_RS25345 87e5e16ab70158e82567148381a3f75d 313 Gene3D G3DSA:3.40.30.10 138 213 1.9E-8 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS25345 87e5e16ab70158e82567148381a3f75d 313 SUPERFAMILY SSF52833 134 214 1.27E-9 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS19960 47f8e4d3ed8eee1b8d54d7ea67ffa866 317 Gene3D G3DSA:3.30.420.40 2 125 1.1E-49 T 06-07-2017 LK06_RS19960 47f8e4d3ed8eee1b8d54d7ea67ffa866 317 SUPERFAMILY SSF53067 134 310 9.93E-39 T 06-07-2017 LK06_RS19960 47f8e4d3ed8eee1b8d54d7ea67ffa866 317 Gene3D G3DSA:3.30.420.150 133 309 8.8E-60 T 06-07-2017 LK06_RS19960 47f8e4d3ed8eee1b8d54d7ea67ffa866 317 SUPERFAMILY SSF53067 3 124 7.28E-34 T 06-07-2017 LK06_RS19960 47f8e4d3ed8eee1b8d54d7ea67ffa866 317 Pfam PF02541 Ppx/GppA phosphatase family 23 303 1.4E-59 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 LK06_RS06900 4b84b6345b21833c0fd1dc4dd260af24 402 SUPERFAMILY SSF53822 34 394 1.08E-79 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS06900 4b84b6345b21833c0fd1dc4dd260af24 402 Pfam PF13458 Periplasmic binding protein 34 390 1.5E-50 T 06-07-2017 IPR028081 Leucine-binding protein domain LK06_RS06900 4b84b6345b21833c0fd1dc4dd260af24 402 Gene3D G3DSA:3.40.50.2300 34 243 1.1E-54 T 06-07-2017 LK06_RS17150 f83e3f72938779182d698ad0404abf71 309 Pfam PF10935 Protein of unknown function (DUF2637) 32 159 1.3E-12 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 LK06_RS23070 42b04a2635ef2c4aa3a98e3abed2504b 153 SUPERFAMILY SSF50998 58 122 1.04E-5 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LK06_RS23070 42b04a2635ef2c4aa3a98e3abed2504b 153 Gene3D G3DSA:2.140.10.10 57 120 3.1E-6 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS08170 0ca786a85d3ae7ac05768f0f09d767d2 423 Gene3D G3DSA:1.20.1250.20 202 380 2.0E-9 T 06-07-2017 LK06_RS08170 0ca786a85d3ae7ac05768f0f09d767d2 423 SUPERFAMILY SSF103473 3 379 3.92E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS08170 0ca786a85d3ae7ac05768f0f09d767d2 423 Pfam PF07690 Major Facilitator Superfamily 8 338 8.8E-38 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS08170 0ca786a85d3ae7ac05768f0f09d767d2 423 Gene3D G3DSA:1.20.1250.20 5 186 8.1E-27 T 06-07-2017 LK06_RS11615 292f85bfa94ecaa66e1caa7fbf4eb2c6 464 Gene3D G3DSA:3.40.190.10 194 387 7.9E-27 T 06-07-2017 LK06_RS11615 292f85bfa94ecaa66e1caa7fbf4eb2c6 464 Pfam PF13416 Bacterial extracellular solute-binding protein 84 392 1.5E-21 T 06-07-2017 LK06_RS11615 292f85bfa94ecaa66e1caa7fbf4eb2c6 464 SUPERFAMILY SSF53850 63 459 6.21E-52 T 06-07-2017 LK06_RS11615 292f85bfa94ecaa66e1caa7fbf4eb2c6 464 Gene3D G3DSA:3.40.190.10 72 193 7.6E-23 T 06-07-2017 LK06_RS04540 657031da90422d7de18f0ca0dc2110c2 91 Pfam PF13453 Transcription factor zinc-finger 2 40 1.3E-17 T 06-07-2017 IPR027392 Transcription factor zinc-finger LK06_RS01545 102fa8ea7792c221abaf74eb2c8847dd 320 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 190 314 6.5E-41 T 06-07-2017 IPR019257 Histidine-specific methyltransferase, SAM-dependent LK06_RS01545 102fa8ea7792c221abaf74eb2c8847dd 320 PIRSF PIRSF018005 2 320 9.2E-138 T 06-07-2017 IPR017804 Methyltransferase EgtD-like LK06_RS01545 102fa8ea7792c221abaf74eb2c8847dd 320 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 6 319 55.614 T 06-07-2017 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 LK06_RS01545 102fa8ea7792c221abaf74eb2c8847dd 320 SUPERFAMILY SSF53335 282 310 8.33E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS01545 102fa8ea7792c221abaf74eb2c8847dd 320 SUPERFAMILY SSF53335 35 193 8.33E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS01545 102fa8ea7792c221abaf74eb2c8847dd 320 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 19 316 4.0E-116 T 06-07-2017 IPR017804 Methyltransferase EgtD-like LK06_RS01545 102fa8ea7792c221abaf74eb2c8847dd 320 Gene3D G3DSA:3.40.50.150 54 215 2.1E-7 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28875 3ac75d4ce2436439faa893f9c1e42d1a 420 Gene3D G3DSA:3.40.50.980 64 208 3.1E-4 T 06-07-2017 LK06_RS28875 3ac75d4ce2436439faa893f9c1e42d1a 420 SUPERFAMILY SSF56801 32 372 1.96E-20 T 06-07-2017 LK06_RS25895 bfaf8d1b09d12b1ba05501c1e613155c 649 Pfam PF07940 Heparinase II/III-like protein 400 635 7.7E-48 T 06-07-2017 IPR012480 Heparinase II/III-like GO:0016829 LK06_RS25895 bfaf8d1b09d12b1ba05501c1e613155c 649 Gene3D G3DSA:1.50.10.110 92 334 4.9E-10 T 06-07-2017 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 LK06_RS25895 bfaf8d1b09d12b1ba05501c1e613155c 649 SUPERFAMILY SSF48230 92 355 1.28E-31 T 06-07-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 LK06_RS25895 bfaf8d1b09d12b1ba05501c1e613155c 649 Pfam PF16889 Heparinase II/III N-terminus 121 327 2.9E-16 T 06-07-2017 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 LK06_RS01290 6fabaa2e77ddd2463b4c466cd03d87ac 433 SUPERFAMILY SSF53474 16 291 2.63E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS01290 6fabaa2e77ddd2463b4c466cd03d87ac 433 Pfam PF00561 alpha/beta hydrolase fold 49 240 1.3E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS01290 6fabaa2e77ddd2463b4c466cd03d87ac 433 Gene3D G3DSA:3.40.50.1820 315 426 2.2E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS01290 6fabaa2e77ddd2463b4c466cd03d87ac 433 Gene3D G3DSA:3.40.50.1820 15 243 2.2E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS01290 6fabaa2e77ddd2463b4c466cd03d87ac 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 140 154 7.5E-9 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 LK06_RS01290 6fabaa2e77ddd2463b4c466cd03d87ac 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 59 7.5E-9 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 LK06_RS01290 6fabaa2e77ddd2463b4c466cd03d87ac 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 81 92 7.5E-9 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 LK06_RS25915 2e4ded84cf942d2151af332a7f4fb5d1 455 Pfam PF02706 Chain length determinant protein 4 125 1.9E-6 T 06-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 LK06_RS26720 b931c514d6b69921c912bf9667e477dd 118 Pfam PF02627 Carboxymuconolactone decarboxylase family 9 87 1.3E-5 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS26720 b931c514d6b69921c912bf9667e477dd 118 Gene3D G3DSA:1.20.1290.10 12 116 2.1E-8 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS26720 b931c514d6b69921c912bf9667e477dd 118 SUPERFAMILY SSF69118 20 92 5.22E-9 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS28565 4bc70e89a4976abf5b1ae3e5a92230d1 81 Pfam PF02467 Transcription factor WhiB 16 76 6.6E-23 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS28565 4bc70e89a4976abf5b1ae3e5a92230d1 81 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 79 16.218 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS20255 9a33a21d1c10f25c84af601aee8d2ebb 432 Pfam PF04024 PspC domain 13 68 4.6E-14 T 06-07-2017 IPR007168 Phage shock protein, PspC, N-terminal LK06_RS05125 caa611c27e4732598d3e24e22a174c29 329 SUPERFAMILY SSF159659 3 260 9.68E-89 T 06-07-2017 LK06_RS05125 caa611c27e4732598d3e24e22a174c29 329 Pfam PF09754 PAC2 family 19 236 4.6E-53 T 06-07-2017 IPR019151 Proteasome assembly chaperone 2 LK06_RS05125 caa611c27e4732598d3e24e22a174c29 329 PIRSF PIRSF028754 2 288 2.2E-123 T 06-07-2017 IPR008492 Protein of unknown function DUF774 LK06_RS02315 0e7cbc5bcbf184f10d487c7b0570398f 100 PIRSF PIRSF001223 1 100 2.2E-52 T 06-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02315 0e7cbc5bcbf184f10d487c7b0570398f 100 SUPERFAMILY SSF54111 2 99 2.88E-46 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02315 0e7cbc5bcbf184f10d487c7b0570398f 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.882 T 06-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02315 0e7cbc5bcbf184f10d487c7b0570398f 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 2.0E-44 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02315 0e7cbc5bcbf184f10d487c7b0570398f 100 Gene3D G3DSA:3.30.280.10 2 99 4.3E-50 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02315 0e7cbc5bcbf184f10d487c7b0570398f 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 2 99 5.4E-51 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS02315 0e7cbc5bcbf184f10d487c7b0570398f 100 Pfam PF00547 Urease, gamma subunit 2 99 5.0E-48 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 LK06_RS15615 3af0db7b0e06765de6f8a5865fee622f 229 Gene3D G3DSA:2.40.260.10 77 217 7.0E-24 T 06-07-2017 IPR023365 Sortase domain LK06_RS15615 3af0db7b0e06765de6f8a5865fee622f 229 SUPERFAMILY SSF63817 67 218 2.62E-30 T 06-07-2017 IPR023365 Sortase domain LK06_RS15615 3af0db7b0e06765de6f8a5865fee622f 229 TIGRFAM TIGR01076 sortase_fam: sortase 84 212 1.5E-13 T 06-07-2017 IPR005754 Sortase family LK06_RS15615 3af0db7b0e06765de6f8a5865fee622f 229 Pfam PF04203 Sortase family 82 213 2.3E-25 T 06-07-2017 IPR005754 Sortase family LK06_RS16550 76f234941be2e0f77ee2bc705b47b2e0 279 Pfam PF13586 Transposase DDE domain 197 260 1.6E-12 T 06-07-2017 IPR025668 Transposase DDE domain LK06_RS16550 76f234941be2e0f77ee2bc705b47b2e0 279 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 90 3.6E-24 T 06-07-2017 IPR025161 Putative transposase IS4/IS5 family LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 Gene3D G3DSA:1.10.630.10 9 405 2.4E-125 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 SUPERFAMILY SSF48264 11 405 1.22E-95 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 Pfam PF00067 Cytochrome P450 190 376 3.1E-24 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 PRINTS PR00359 B-class P450 signature 282 293 1.3E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 PRINTS PR00359 B-class P450 signature 327 342 1.3E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 PRINTS PR00359 B-class P450 signature 158 173 1.3E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 PRINTS PR00359 B-class P450 signature 348 357 1.3E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 PRINTS PR00359 B-class P450 signature 201 223 1.3E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 PRINTS PR00359 B-class P450 signature 357 368 1.3E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 PRINTS PR00359 B-class P450 signature 141 157 1.3E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 PRINTS PR00359 B-class P450 signature 95 106 1.3E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS14570 bcda137e408595ddac8788db7bd3980a 406 PRINTS PR00359 B-class P450 signature 299 326 1.3E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 LK06_RS27660 22e0883501f92a6bbba59c471709b0ab 155 Pfam PF01613 Flavin reductase like domain 1 146 8.3E-36 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS27660 22e0883501f92a6bbba59c471709b0ab 155 Gene3D G3DSA:2.30.110.10 1 144 6.0E-45 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS27660 22e0883501f92a6bbba59c471709b0ab 155 SUPERFAMILY SSF50475 1 145 9.32E-44 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS27660 22e0883501f92a6bbba59c471709b0ab 155 SMART SM00903 1 145 2.3E-49 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 LK06_RS19030 2b5ea5b32d6fa8e33e8dd86ebcfb3bc4 262 SUPERFAMILY SSF51735 6 261 5.29E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS19030 2b5ea5b32d6fa8e33e8dd86ebcfb3bc4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19030 2b5ea5b32d6fa8e33e8dd86ebcfb3bc4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.1E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19030 2b5ea5b32d6fa8e33e8dd86ebcfb3bc4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.1E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19030 2b5ea5b32d6fa8e33e8dd86ebcfb3bc4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.1E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19030 2b5ea5b32d6fa8e33e8dd86ebcfb3bc4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.1E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19030 2b5ea5b32d6fa8e33e8dd86ebcfb3bc4 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 258 2.2E-40 T 06-07-2017 LK06_RS19030 2b5ea5b32d6fa8e33e8dd86ebcfb3bc4 262 Gene3D G3DSA:3.40.50.720 3 259 1.4E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12835 a8d962adf60ac68af7c607673bd15bb9 669 Pfam PF00583 Acetyltransferase (GNAT) family 54 135 7.2E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS12835 a8d962adf60ac68af7c607673bd15bb9 669 Gene3D G3DSA:3.40.630.30 1 141 1.9E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS12835 a8d962adf60ac68af7c607673bd15bb9 669 SUPERFAMILY SSF55729 1 141 1.19E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS03410 68dfb040a2305d7d5ecd2f861e021daa 693 SUPERFAMILY SSF53098 250 315 5.99E-11 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03410 68dfb040a2305d7d5ecd2f861e021daa 693 SUPERFAMILY SSF53098 351 412 5.99E-11 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03410 68dfb040a2305d7d5ecd2f861e021daa 693 Gene3D G3DSA:3.30.420.10 347 457 1.3E-19 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03410 68dfb040a2305d7d5ecd2f861e021daa 693 Gene3D G3DSA:3.30.420.10 253 309 1.3E-19 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03410 68dfb040a2305d7d5ecd2f861e021daa 693 Pfam PF00665 Integrase core domain 252 405 3.7E-11 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 LK06_RS04840 635bbd58ae376ce15af0d7d477ed2816 320 SUPERFAMILY SSF56601 92 302 2.71E-21 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS04840 635bbd58ae376ce15af0d7d477ed2816 320 Gene3D G3DSA:3.40.710.10 97 316 1.9E-17 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS08685 b3e10380b74197df9d79ae1a971610bd 151 Pfam PF07681 DoxX 15 93 3.0E-8 T 06-07-2017 IPR032808 DoxX family LK06_RS16745 89c818b4da420fbedd4994318c55f5a3 73 SUPERFAMILY SSF141259 24 69 3.92E-5 T 06-07-2017 IPR003711 CarD-like/TRCF domain LK06_RS11195 fa624dead5aa06566f3490fc41d3a547 153 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 56 149 2.8E-8 T 06-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 LK06_RS11195 fa624dead5aa06566f3490fc41d3a547 153 Gene3D G3DSA:2.30.30.110 53 150 8.0E-4 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor LK06_RS11195 fa624dead5aa06566f3490fc41d3a547 153 SUPERFAMILY SSF50118 55 150 2.83E-10 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor LK06_RS08730 5d7d171c3624cf9552a251363069393a 431 Gene3D G3DSA:3.20.20.370 101 277 4.9E-12 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS08730 5d7d171c3624cf9552a251363069393a 431 Gene3D G3DSA:3.20.20.370 324 407 4.9E-12 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS08730 5d7d171c3624cf9552a251363069393a 431 SUPERFAMILY SSF88713 107 148 4.45E-24 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS08730 5d7d171c3624cf9552a251363069393a 431 SUPERFAMILY SSF88713 178 409 4.45E-24 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS12730 46dd31d87981c6474fc0f3c6e653b213 294 Pfam PF12730 ABC-2 family transporter protein 81 202 8.8E-10 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 LK06_RS18125 7cb792e1ca129a41f39dc6bbc9a326c4 461 SUPERFAMILY SSF53756 132 358 5.14E-17 T 06-07-2017 LK06_RS18125 7cb792e1ca129a41f39dc6bbc9a326c4 461 Gene3D G3DSA:3.40.50.2000 194 357 2.7E-21 T 06-07-2017 LK06_RS18125 7cb792e1ca129a41f39dc6bbc9a326c4 461 Pfam PF13692 Glycosyl transferases group 1 244 355 5.3E-8 T 06-07-2017 LK06_RS18125 7cb792e1ca129a41f39dc6bbc9a326c4 461 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 56 198 4.9E-6 T 06-07-2017 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 LK06_RS03015 aa3fe7889414aa35a67324a5de1cb73d 214 Pfam PF09335 SNARE associated Golgi protein 32 159 4.7E-19 T 06-07-2017 IPR032816 SNARE associated Golgi protein LK06_RS10925 543abf3cfaa95d853ed071490f9aa077 261 PIRSF PIRSF015736 7 247 9.5E-63 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase LK06_RS07115 fc852d71618d56fe13b7d7131c4928df 211 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 5 203 9.6E-81 T 06-07-2017 IPR017519 Conserved hypothetical protein CHP03085 LK06_RS07115 fc852d71618d56fe13b7d7131c4928df 211 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 185 4.2E-39 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type LK06_RS07115 fc852d71618d56fe13b7d7131c4928df 211 SUPERFAMILY SSF109854 13 114 1.92E-6 T 06-07-2017 LK06_RS15745 f2f6c8021a212097905804ac28ace6c5 176 Pfam PF08378 Nuclease-related domain 19 120 3.1E-11 T 06-07-2017 IPR011528 Nuclease-related domain, NERD LK06_RS15025 e0584bd6c2ac0845d395c28931d9ace2 226 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 17 201 3.0E-26 T 06-07-2017 LK06_RS19370 789d26c181c7b7e279c8a501ece7dd82 300 Gene3D G3DSA:3.90.550.10 10 282 6.4E-75 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS19370 789d26c181c7b7e279c8a501ece7dd82 300 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 273 3.5E-105 T 06-07-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 LK06_RS19370 789d26c181c7b7e279c8a501ece7dd82 300 SUPERFAMILY SSF53448 10 291 1.87E-64 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS19370 789d26c181c7b7e279c8a501ece7dd82 300 Pfam PF00483 Nucleotidyl transferase 10 274 1.3E-27 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LK06_RS03590 58d0ce30efe2b3b9baacc99e06517d90 274 Gene3D G3DSA:3.40.190.10 50 172 1.3E-34 T 06-07-2017 LK06_RS03590 58d0ce30efe2b3b9baacc99e06517d90 274 PIRSF PIRSF004846 7 274 8.4E-62 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 LK06_RS03590 58d0ce30efe2b3b9baacc99e06517d90 274 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 59 268 8.8E-41 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 LK06_RS03590 58d0ce30efe2b3b9baacc99e06517d90 274 Pfam PF13531 Bacterial extracellular solute-binding protein 54 271 1.4E-43 T 06-07-2017 LK06_RS03590 58d0ce30efe2b3b9baacc99e06517d90 274 Gene3D G3DSA:3.40.190.10 173 224 2.2E-8 T 06-07-2017 LK06_RS03590 58d0ce30efe2b3b9baacc99e06517d90 274 SUPERFAMILY SSF53850 53 274 2.18E-49 T 06-07-2017 LK06_RS03240 2fb1e0708df927f5d1427f0aaefeb0e7 242 Gene3D G3DSA:3.40.50.1820 3 234 1.5E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS03240 2fb1e0708df927f5d1427f0aaefeb0e7 242 Pfam PF00975 Thioesterase domain 6 229 1.4E-33 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS03240 2fb1e0708df927f5d1427f0aaefeb0e7 242 SUPERFAMILY SSF53474 4 231 7.77E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS09355 7b7521ec119f9754d77a339e7d530bd8 404 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 348 2.0E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS09355 7b7521ec119f9754d77a339e7d530bd8 404 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 393 2.0E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS09355 7b7521ec119f9754d77a339e7d530bd8 404 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 374 2.0E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LK06_RS09355 7b7521ec119f9754d77a339e7d530bd8 404 Gene3D G3DSA:3.30.565.10 291 400 4.4E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS09355 7b7521ec119f9754d77a339e7d530bd8 404 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 394 1.5E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS09355 7b7521ec119f9754d77a339e7d530bd8 404 SMART SM00387 298 396 4.4E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS09355 7b7521ec119f9754d77a339e7d530bd8 404 SUPERFAMILY SSF55874 267 395 7.47E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS09355 7b7521ec119f9754d77a339e7d530bd8 404 PIRSF PIRSF037434 2 401 1.2E-135 T 06-07-2017 IPR017205 Signal transduction histidine kinase, ChrS LK06_RS09355 7b7521ec119f9754d77a339e7d530bd8 404 Pfam PF07730 Histidine kinase 193 260 2.0E-17 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS07405 2909bf07ab44855625aedda1c4db06d0 307 SUPERFAMILY SSF51730 15 301 1.47E-92 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like LK06_RS07405 2909bf07ab44855625aedda1c4db06d0 307 Pfam PF02219 Methylenetetrahydrofolate reductase 16 300 5.1E-109 T 06-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 LK06_RS07405 2909bf07ab44855625aedda1c4db06d0 307 Gene3D G3DSA:3.20.20.220 12 303 2.7E-102 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like LK06_RS07405 2909bf07ab44855625aedda1c4db06d0 307 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 27 299 9.0E-95 T 06-07-2017 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 LK06_RS19445 0a511c77803550b9cf67a400b342de29 278 Pfam PF13814 Replication-relaxation 34 221 8.8E-30 T 06-07-2017 IPR025855 Plasmid replication-relaxation LK06_RS31760 6e3e3d60cadc0a4232a7b7ad908aed20 78 SUPERFAMILY SSF47336 7 73 9.78E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29240 88c78502af01e73da3e850802d7c8c41 161 SUPERFAMILY SSF46785 16 147 3.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29240 88c78502af01e73da3e850802d7c8c41 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 4.2E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29240 88c78502af01e73da3e850802d7c8c41 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 4.2E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29240 88c78502af01e73da3e850802d7c8c41 161 SMART SM00347 35 136 2.3E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS29240 88c78502af01e73da3e850802d7c8c41 161 Gene3D G3DSA:1.10.10.10 16 148 2.4E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29240 88c78502af01e73da3e850802d7c8c41 161 Pfam PF12802 MarR family 41 100 6.6E-14 T 06-07-2017 LK06_RS10750 34ac804c0bfa64d11e63b04c7cf69164 414 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 1 327 1.1E-119 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase LK06_RS10750 34ac804c0bfa64d11e63b04c7cf69164 414 SUPERFAMILY SSF51905 3 241 7.55E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10750 34ac804c0bfa64d11e63b04c7cf69164 414 Gene3D G3DSA:3.50.50.60 79 212 6.0E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS13645 d028cafd159682dc783445bac6c62e6d 210 Gene3D G3DSA:3.40.50.1000 81 130 3.5E-7 T 06-07-2017 IPR023214 HAD-like domain LK06_RS13645 d028cafd159682dc783445bac6c62e6d 210 SUPERFAMILY SSF56784 78 196 7.05E-10 T 06-07-2017 IPR023214 HAD-like domain LK06_RS13645 d028cafd159682dc783445bac6c62e6d 210 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 20 99 1.3E-8 T 06-07-2017 IPR005519 Acid phosphatase, class B-like LK06_RS13645 d028cafd159682dc783445bac6c62e6d 210 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 103 206 7.9E-19 T 06-07-2017 IPR005519 Acid phosphatase, class B-like LK06_RS09125 d5d9b94dae65ff2fbd2eec9af710aa6a 45 SUPERFAMILY SSF56349 2 44 2.59E-5 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS09125 d5d9b94dae65ff2fbd2eec9af710aa6a 45 Gene3D G3DSA:1.10.150.130 3 44 1.2E-5 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal LK06_RS09125 d5d9b94dae65ff2fbd2eec9af710aa6a 45 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 8 44 3.7E-8 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LK06_RS28165 26898e641d691925785a18a47a606ced 164 SUPERFAMILY SSF89155 5 155 7.06E-23 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone LK06_RS28165 26898e641d691925785a18a47a606ced 164 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 15 150 7.2E-21 T 06-07-2017 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 LK06_RS28165 26898e641d691925785a18a47a606ced 164 Pfam PF02613 Nitrate reductase delta subunit 29 144 8.1E-10 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone LK06_RS20425 6bbb66d5931d6749c017f48a2b87f03c 672 SUPERFAMILY SSF161098 479 664 1.57E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS20425 6bbb66d5931d6749c017f48a2b87f03c 672 SUPERFAMILY SSF161098 157 339 4.97E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS20425 6bbb66d5931d6749c017f48a2b87f03c 672 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 500 658 1.8E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS20425 6bbb66d5931d6749c017f48a2b87f03c 672 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 181 340 9.1E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS20425 6bbb66d5931d6749c017f48a2b87f03c 672 Gene3D G3DSA:1.10.3720.10 38 65 3.4E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS20425 6bbb66d5931d6749c017f48a2b87f03c 672 Gene3D G3DSA:1.10.3720.10 478 663 5.3E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS20425 6bbb66d5931d6749c017f48a2b87f03c 672 Gene3D G3DSA:1.10.3720.10 142 335 3.4E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS29385 ce4fed49ae7b33783f0b02da5cd04d9b 763 SUPERFAMILY SSF82866 165 382 4.19E-31 T 06-07-2017 LK06_RS29385 ce4fed49ae7b33783f0b02da5cd04d9b 763 SUPERFAMILY SSF82866 520 749 7.85E-25 T 06-07-2017 LK06_RS29385 ce4fed49ae7b33783f0b02da5cd04d9b 763 Gene3D G3DSA:1.20.1640.10 193 385 3.1E-31 T 06-07-2017 LK06_RS29385 ce4fed49ae7b33783f0b02da5cd04d9b 763 Gene3D G3DSA:1.20.1640.10 549 754 1.2E-29 T 06-07-2017 LK06_RS29385 ce4fed49ae7b33783f0b02da5cd04d9b 763 Pfam PF03176 MMPL family 103 413 7.4E-53 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS29385 ce4fed49ae7b33783f0b02da5cd04d9b 763 Pfam PF03176 MMPL family 490 753 3.6E-28 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS08295 54a15ad494557f4ea7da33faf6020240 422 SUPERFAMILY SSF54909 61 411 1.56E-95 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS08295 54a15ad494557f4ea7da33faf6020240 422 Pfam PF04261 Dyp-type peroxidase family 66 407 1.5E-120 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LK06_RS08295 54a15ad494557f4ea7da33faf6020240 422 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 66 407 5.6E-106 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LK06_RS08295 54a15ad494557f4ea7da33faf6020240 422 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 14 418 1.0E-173 T 06-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 LK06_RS04910 9918d42c65f7efc84d8c51580aa3a006 281 Pfam PF08021 Siderophore-interacting FAD-binding domain 16 131 1.8E-39 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting LK06_RS04910 9918d42c65f7efc84d8c51580aa3a006 281 Gene3D G3DSA:2.40.30.10 7 130 4.5E-36 T 06-07-2017 LK06_RS04910 9918d42c65f7efc84d8c51580aa3a006 281 Gene3D G3DSA:3.40.50.80 133 274 8.6E-51 T 06-07-2017 LK06_RS04910 9918d42c65f7efc84d8c51580aa3a006 281 Pfam PF04954 Siderophore-interacting protein 138 253 8.7E-38 T 06-07-2017 IPR007037 Siderophore-interacting protein LK06_RS04910 9918d42c65f7efc84d8c51580aa3a006 281 SUPERFAMILY SSF63380 7 135 6.43E-13 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 LK06_RS06260 fe2c1b5f32dba8967db3eb5b6f8a10c5 243 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 215 9.5E-43 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06260 fe2c1b5f32dba8967db3eb5b6f8a10c5 243 PIRSF PIRSF036427 1 239 1.8E-71 T 06-07-2017 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 LK06_RS06260 fe2c1b5f32dba8967db3eb5b6f8a10c5 243 SUPERFAMILY SSF53790 1 234 2.36E-41 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06260 fe2c1b5f32dba8967db3eb5b6f8a10c5 243 Gene3D G3DSA:3.40.1010.10 1 131 8.5E-30 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 LK06_RS06260 fe2c1b5f32dba8967db3eb5b6f8a10c5 243 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 4 231 8.3E-72 T 06-07-2017 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 LK06_RS22015 fad697f173f0b4d4963abba8b5eaf8f3 74 Pfam PF11314 Protein of unknown function (DUF3117) 23 72 9.3E-29 T 06-07-2017 IPR021465 Protein of unknown function DUF3117 LK06_RS06375 00fda7398e95f9b22b320522a467bdcd 53 SMART SM00421 1 44 1.3E-4 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS06375 00fda7398e95f9b22b320522a467bdcd 53 Gene3D G3DSA:1.10.10.10 1 49 4.7E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS06375 00fda7398e95f9b22b320522a467bdcd 53 Pfam PF00196 Bacterial regulatory proteins, luxR family 1 43 1.6E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS06375 00fda7398e95f9b22b320522a467bdcd 53 SUPERFAMILY SSF46894 1 50 1.39E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS09885 728a36a583f0b3e3cdaf48de05740a60 119 Pfam PF14017 Protein of unknown function (DUF4233) 2 105 6.0E-32 T 06-07-2017 IPR025327 Protein of unknown function DUF4233 LK06_RS24735 d2f5c0ee03eccc95f2b3254382c61654 305 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 40 290 7.9E-71 T 06-07-2017 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 LK06_RS24735 d2f5c0ee03eccc95f2b3254382c61654 305 SUPERFAMILY SSF56112 29 279 2.62E-9 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS27385 8b8d628ed6e2f03cb300e0336b8c4544 83 Gene3D G3DSA:3.30.70.930 19 73 1.3E-6 T 06-07-2017 IPR029756 MTH1187/YkoF-like LK06_RS27385 8b8d628ed6e2f03cb300e0336b8c4544 83 SUPERFAMILY SSF89957 1 73 8.24E-8 T 06-07-2017 IPR029756 MTH1187/YkoF-like LK06_RS13945 73109d8a90a8ca045133852b2faff963 403 Pfam PF12704 MacB-like periplasmic core domain 21 244 4.7E-39 T 06-07-2017 IPR025857 MacB-like periplasmic core domain LK06_RS13945 73109d8a90a8ca045133852b2faff963 403 Pfam PF02687 FtsX-like permease family 286 396 1.8E-16 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS17750 1c3c7b3c70b4806274a12ea598cc5c1f 87 Pfam PF01494 FAD binding domain 5 77 6.4E-7 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS17750 1c3c7b3c70b4806274a12ea598cc5c1f 87 SUPERFAMILY SSF51905 1 85 3.11E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS17750 1c3c7b3c70b4806274a12ea598cc5c1f 87 PRINTS PR00419 Adrenodoxin reductase family signature 27 40 7.7E-7 T 06-07-2017 LK06_RS17750 1c3c7b3c70b4806274a12ea598cc5c1f 87 PRINTS PR00419 Adrenodoxin reductase family signature 4 26 7.7E-7 T 06-07-2017 LK06_RS17750 1c3c7b3c70b4806274a12ea598cc5c1f 87 Gene3D G3DSA:3.50.50.60 2 70 2.3E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19415 39c2c688986dbef284e7a561c2ce6448 174 Gene3D G3DSA:3.40.50.1390 23 157 3.3E-24 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 LK06_RS19415 39c2c688986dbef284e7a561c2ce6448 174 Pfam PF00239 Resolvase, N terminal domain 23 174 8.5E-30 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 LK06_RS19415 39c2c688986dbef284e7a561c2ce6448 174 ProSitePatterns PS00397 Site-specific recombinases active site. 26 34 - T 06-07-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 LK06_RS19415 39c2c688986dbef284e7a561c2ce6448 174 SMART SM00857 23 173 6.6E-34 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 LK06_RS19415 39c2c688986dbef284e7a561c2ce6448 174 SUPERFAMILY SSF53041 22 174 1.7E-27 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 LK06_RS17980 81e08e98f65e76170cdf1bfb5b37413b 142 Gene3D G3DSA:3.30.565.10 41 133 2.2E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17980 81e08e98f65e76170cdf1bfb5b37413b 142 Pfam PF13581 Histidine kinase-like ATPase domain 19 129 1.2E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17980 81e08e98f65e76170cdf1bfb5b37413b 142 SUPERFAMILY SSF55874 37 131 8.64E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS02130 8e4b81b93ada146033d4e568f1786c13 298 Gene3D G3DSA:3.20.20.70 5 291 7.2E-82 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS02130 8e4b81b93ada146033d4e568f1786c13 298 Pfam PF00701 Dihydrodipicolinate synthetase family 10 289 2.4E-44 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS02130 8e4b81b93ada146033d4e568f1786c13 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 109 125 3.4E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS02130 8e4b81b93ada146033d4e568f1786c13 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 3.4E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS02130 8e4b81b93ada146033d4e568f1786c13 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 3.4E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS02130 8e4b81b93ada146033d4e568f1786c13 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 42 63 3.4E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS02130 8e4b81b93ada146033d4e568f1786c13 298 SMART SM01130 8 293 1.5E-83 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS02130 8e4b81b93ada146033d4e568f1786c13 298 SUPERFAMILY SSF51569 7 291 9.84E-75 T 06-07-2017 LK06_RS02130 8e4b81b93ada146033d4e568f1786c13 298 PIRSF PIRSF001365 5 295 1.4E-67 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 LK06_RS13875 b0fed2eb6500f5b5d683482551d2cf9a 158 Pfam PF13581 Histidine kinase-like ATPase domain 25 134 6.2E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13875 b0fed2eb6500f5b5d683482551d2cf9a 158 SUPERFAMILY SSF55874 44 139 1.3E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS03315 4bf0a1da8b01d0939ab4068d655b363b 300 SUPERFAMILY SSF46785 1 111 1.05E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03315 4bf0a1da8b01d0939ab4068d655b363b 300 Pfam PF03466 LysR substrate binding domain 88 292 1.4E-40 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS03315 4bf0a1da8b01d0939ab4068d655b363b 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.7E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS03315 4bf0a1da8b01d0939ab4068d655b363b 300 Gene3D G3DSA:3.40.190.10 182 267 1.0E-21 T 06-07-2017 LK06_RS03315 4bf0a1da8b01d0939ab4068d655b363b 300 Gene3D G3DSA:3.40.190.10 91 181 1.2E-17 T 06-07-2017 LK06_RS03315 4bf0a1da8b01d0939ab4068d655b363b 300 Gene3D G3DSA:1.10.10.10 1 88 1.2E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS03315 4bf0a1da8b01d0939ab4068d655b363b 300 SUPERFAMILY SSF53850 89 298 2.64E-34 T 06-07-2017 LK06_RS09870 73b0806a6e74a1bcaa97e623db17e8d3 311 PIRSF PIRSF038471 1 282 1.3E-41 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 LK06_RS09870 73b0806a6e74a1bcaa97e623db17e8d3 311 Pfam PF04085 rod shape-determining protein MreC 129 270 1.0E-34 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 LK06_RS09870 73b0806a6e74a1bcaa97e623db17e8d3 311 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 10 272 1.3E-28 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 LK06_RS13955 7b2b3728363084baa65f21df2ca77547 495 SUPERFAMILY SSF111369 116 269 4.58E-11 T 06-07-2017 LK06_RS13955 7b2b3728363084baa65f21df2ca77547 495 Pfam PF13533 Biotin-lipoyl like 131 177 1.7E-6 T 06-07-2017 LK06_RS13955 7b2b3728363084baa65f21df2ca77547 495 Gene3D G3DSA:2.40.50.100 130 156 9.2E-11 T 06-07-2017 LK06_RS13955 7b2b3728363084baa65f21df2ca77547 495 Gene3D G3DSA:2.40.50.100 243 266 9.2E-11 T 06-07-2017 LK06_RS14160 851aa990af249edf124e899290eb230f 325 Gene3D G3DSA:3.40.50.300 6 227 2.9E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14160 851aa990af249edf124e899290eb230f 325 Pfam PF02374 Anion-transporting ATPase 6 180 9.0E-21 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 LK06_RS14160 851aa990af249edf124e899290eb230f 325 SUPERFAMILY SSF52540 5 227 2.67E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12735 df669bed0c0e43973988a1faf06a2038 360 Pfam PF00005 ABC transporter 72 216 8.9E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS12735 df669bed0c0e43973988a1faf06a2038 360 Gene3D G3DSA:3.40.50.300 48 278 2.5E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12735 df669bed0c0e43973988a1faf06a2038 360 SMART SM00382 80 288 3.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS12735 df669bed0c0e43973988a1faf06a2038 360 SUPERFAMILY SSF52540 51 278 6.03E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12735 df669bed0c0e43973988a1faf06a2038 360 ProSitePatterns PS00211 ABC transporters family signature. 188 202 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS27120 f0098221509a7475c200941e889638e7 557 Pfam PF07905 Purine catabolism regulatory protein-like family 6 120 2.4E-25 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain LK06_RS27120 f0098221509a7475c200941e889638e7 557 Pfam PF13556 PucR C-terminal helix-turn-helix domain 498 555 2.4E-21 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS30540 48292e17359d8273af19cd6b951b1904 268 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 3 234 2.2E-49 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 LK06_RS14635 5cf6f6ebaabd07aab9ef754095b64bdb 176 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 4 157 2.0E-79 T 06-07-2017 IPR024486 Protein of unknown function DUF2617 LK06_RS14635 5cf6f6ebaabd07aab9ef754095b64bdb 176 Pfam PF10936 Protein of unknown function DUF2617 3 164 1.1E-62 T 06-07-2017 IPR024486 Protein of unknown function DUF2617 LK06_RS27520 62aa04a898bc7eeeabccd78fda5e4ae8 541 Gene3D G3DSA:3.20.20.360 72 417 7.4E-119 T 06-07-2017 LK06_RS27520 62aa04a898bc7eeeabccd78fda5e4ae8 541 Pfam PF01274 Malate synthase 18 539 1.1E-204 T 06-07-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 LK06_RS27520 62aa04a898bc7eeeabccd78fda5e4ae8 541 ProSitePatterns PS00510 Malate synthase signature. 270 285 - T 06-07-2017 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 LK06_RS27520 62aa04a898bc7eeeabccd78fda5e4ae8 541 PIRSF PIRSF001363 3 541 1.4E-243 T 06-07-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 LK06_RS27520 62aa04a898bc7eeeabccd78fda5e4ae8 541 SUPERFAMILY SSF51645 18 539 8.63E-184 T 06-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 LK06_RS27520 62aa04a898bc7eeeabccd78fda5e4ae8 541 Gene3D G3DSA:1.20.1220.12 420 533 1.1E-25 T 06-07-2017 LK06_RS27520 62aa04a898bc7eeeabccd78fda5e4ae8 541 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 23 539 1.1E-255 T 06-07-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 LK06_RS07220 d73c3b0199f830c16ecab2b6be0c0683 190 Pfam PF01738 Dienelactone hydrolase family 3 187 1.1E-17 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 LK06_RS07220 d73c3b0199f830c16ecab2b6be0c0683 190 SUPERFAMILY SSF53474 3 186 1.55E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS07220 d73c3b0199f830c16ecab2b6be0c0683 190 Gene3D G3DSA:3.40.50.1820 3 186 9.8E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS29680 dcbe2b7c63de609a51a9e3fbe061de9c 94 SUPERFAMILY SSF143800 2 87 2.47E-14 T 06-07-2017 LK06_RS29680 dcbe2b7c63de609a51a9e3fbe061de9c 94 TIGRFAM TIGR00105 L31: ribosomal protein bL31 3 87 8.1E-13 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS29680 dcbe2b7c63de609a51a9e3fbe061de9c 94 Pfam PF01197 Ribosomal protein L31 64 86 1.4E-5 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS29680 dcbe2b7c63de609a51a9e3fbe061de9c 94 Pfam PF01197 Ribosomal protein L31 3 64 2.4E-15 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS24515 6bdc7d28cac9bfbd9db2367bc70d2bc1 377 Pfam PF01148 Cytidylyltransferase family 117 370 1.2E-63 T 06-07-2017 LK06_RS24515 6bdc7d28cac9bfbd9db2367bc70d2bc1 377 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 331 357 - T 06-07-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 LK06_RS25870 803f5f4c756f203f9207a98111daab0a 274 Gene3D G3DSA:3.90.550.10 1 254 8.5E-44 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS25870 803f5f4c756f203f9207a98111daab0a 274 SUPERFAMILY SSF53448 1 255 8.34E-43 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS32045 20ae3d4d25503d23ae072354bf5097bf 188 SUPERFAMILY SSF46894 118 188 2.04E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS32045 20ae3d4d25503d23ae072354bf5097bf 188 Pfam PF00196 Bacterial regulatory proteins, luxR family 128 182 1.9E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS32045 20ae3d4d25503d23ae072354bf5097bf 188 Gene3D G3DSA:1.10.10.10 127 188 2.8E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS32045 20ae3d4d25503d23ae072354bf5097bf 188 SMART SM00421 125 182 5.5E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS32045 20ae3d4d25503d23ae072354bf5097bf 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 128 142 1.3E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS32045 20ae3d4d25503d23ae072354bf5097bf 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 170 1.3E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS32045 20ae3d4d25503d23ae072354bf5097bf 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 158 1.3E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LK06_RS16985 e3dc8a81b99d0ee936493dadbb041560 455 SUPERFAMILY SSF55874 302 429 1.12E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS16985 e3dc8a81b99d0ee936493dadbb041560 455 Pfam PF07730 Histidine kinase 219 286 3.6E-14 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS16985 e3dc8a81b99d0ee936493dadbb041560 455 Gene3D G3DSA:3.30.565.10 302 365 4.6E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 SUPERFAMILY SSF51735 4 249 6.33E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 Pfam PF00106 short chain dehydrogenase 9 197 1.2E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 Gene3D G3DSA:3.40.50.720 8 208 1.2E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS19605 a26372dd1c9d3a1138c1c330c67d5226 294 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 188 5.0E-4 T 06-07-2017 LK06_RS22760 f1c40650406564f5bf2545be3ebe7bb5 453 Pfam PF01098 Cell cycle protein 91 441 1.0E-70 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 LK06_RS27865 3bc1acd1cb210db12e179af60ef48974 342 SUPERFAMILY SSF51679 1 335 8.51E-57 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS27865 3bc1acd1cb210db12e179af60ef48974 342 Gene3D G3DSA:3.20.20.30 1 338 1.6E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS27865 3bc1acd1cb210db12e179af60ef48974 342 Pfam PF00296 Luciferase-like monooxygenase 6 312 3.7E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS27865 3bc1acd1cb210db12e179af60ef48974 342 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 337 5.0E-171 T 06-07-2017 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 LK06_RS25485 8b8861a321960e2e4113f88db3c6ee04 253 Pfam PF12502 Protein of unknown function (DUF3710) 49 222 8.8E-62 T 06-07-2017 IPR022183 Protein of unknown function DUF3710 LK06_RS22000 37248a3101a37cfcbcb3edd9fc20c132 120 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 52 82 1.2E-8 T 06-07-2017 IPR019933 DivIVA domain LK06_RS06580 ec3a2414eee79a8ce9d063acf591ef20 423 Pfam PF01547 Bacterial extracellular solute-binding protein 51 337 2.5E-36 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 LK06_RS06580 ec3a2414eee79a8ce9d063acf591ef20 423 Gene3D G3DSA:3.40.190.10 165 358 4.0E-50 T 06-07-2017 LK06_RS06580 ec3a2414eee79a8ce9d063acf591ef20 423 Gene3D G3DSA:3.40.190.10 36 164 1.8E-20 T 06-07-2017 LK06_RS06580 ec3a2414eee79a8ce9d063acf591ef20 423 SUPERFAMILY SSF53850 45 418 7.41E-78 T 06-07-2017 LK06_RS27275 0c3a29c63654165902f577fe70f4a64c 699 Pfam PF13454 FAD-NAD(P)-binding 10 202 1.7E-43 T 06-07-2017 LK06_RS27275 0c3a29c63654165902f577fe70f4a64c 699 Gene3D G3DSA:3.50.50.60 7 209 5.1E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS27275 0c3a29c63654165902f577fe70f4a64c 699 SUPERFAMILY SSF51905 6 257 2.46E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20445 4f5e0ab224d536b4c0a12548314a3178 169 SUPERFAMILY SSF69118 20 161 3.66E-39 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS20445 4f5e0ab224d536b4c0a12548314a3178 169 Gene3D G3DSA:1.20.1290.10 19 165 2.3E-48 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS20445 4f5e0ab224d536b4c0a12548314a3178 169 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 44 93 1.1E-16 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS20445 4f5e0ab224d536b4c0a12548314a3178 169 Pfam PF02627 Carboxymuconolactone decarboxylase family 28 109 6.7E-16 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LK06_RS11895 af8538588c20e79c828729946028a536 87 Pfam PF02467 Transcription factor WhiB 19 82 6.1E-27 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS11895 af8538588c20e79c828729946028a536 87 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 87 18.896 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS07615 60d433bf2e7977ad728ea25c5cc4f5e9 545 SUPERFAMILY SSF81342 23 300 7.85E-63 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 LK06_RS07615 60d433bf2e7977ad728ea25c5cc4f5e9 545 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 124 297 4.6E-56 T 06-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 LK06_RS07615 60d433bf2e7977ad728ea25c5cc4f5e9 545 Gene3D G3DSA:1.20.810.10 23 444 3.9E-91 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 LK06_RS21455 3db48742fc704bf73add1a8cb36d88f8 251 Pfam PF10137 Predicted nucleotide-binding protein containing TIR-like domain 70 201 2.4E-26 T 06-07-2017 IPR019302 Nucleotide-binding protein, predicted, TIR-like domain LK06_RS01550 587abdf0ae0bc1d83787b6b8c9ea629e 418 Gene3D G3DSA:3.40.190.10 29 159 2.2E-15 T 06-07-2017 LK06_RS01550 587abdf0ae0bc1d83787b6b8c9ea629e 418 Pfam PF01547 Bacterial extracellular solute-binding protein 43 329 2.3E-35 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 LK06_RS01550 587abdf0ae0bc1d83787b6b8c9ea629e 418 Gene3D G3DSA:3.40.190.10 160 346 2.6E-37 T 06-07-2017 LK06_RS01550 587abdf0ae0bc1d83787b6b8c9ea629e 418 SUPERFAMILY SSF53850 25 409 3.56E-61 T 06-07-2017 LK06_RS13740 08c650eb0dabf7002a0441cfdd1d7707 383 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 4 383 40.434 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS13740 08c650eb0dabf7002a0441cfdd1d7707 383 Gene3D G3DSA:1.10.645.10 16 371 1.5E-58 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS13740 08c650eb0dabf7002a0441cfdd1d7707 383 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 134 306 1.1E-44 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS13740 08c650eb0dabf7002a0441cfdd1d7707 383 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 309 383 1.7E-20 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS13740 08c650eb0dabf7002a0441cfdd1d7707 383 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 56 67 - T 06-07-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS13740 08c650eb0dabf7002a0441cfdd1d7707 383 SUPERFAMILY SSF56762 29 382 2.22E-101 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS26285 b1fa1565cb99bce37e12894f3770820b 206 SMART SM00448 16 129 2.1E-6 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS26285 b1fa1565cb99bce37e12894f3770820b 206 Gene3D G3DSA:3.40.50.2300 15 136 4.7E-19 T 06-07-2017 LK06_RS26285 b1fa1565cb99bce37e12894f3770820b 206 SUPERFAMILY SSF52172 16 147 4.7E-22 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS26285 b1fa1565cb99bce37e12894f3770820b 206 Pfam PF00072 Response regulator receiver domain 18 128 5.5E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS12550 7c26dcd0f428372b178348c5cc4016ff 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS12550 7c26dcd0f428372b178348c5cc4016ff 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS12550 7c26dcd0f428372b178348c5cc4016ff 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS12550 7c26dcd0f428372b178348c5cc4016ff 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.5E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS12550 7c26dcd0f428372b178348c5cc4016ff 317 Gene3D G3DSA:3.40.190.10 101 216 2.7E-8 T 06-07-2017 LK06_RS12550 7c26dcd0f428372b178348c5cc4016ff 317 Pfam PF03466 LysR substrate binding domain 97 293 4.3E-15 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS12550 7c26dcd0f428372b178348c5cc4016ff 317 SUPERFAMILY SSF46785 1 84 1.21E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12550 7c26dcd0f428372b178348c5cc4016ff 317 Gene3D G3DSA:1.10.10.10 1 83 5.7E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS12550 7c26dcd0f428372b178348c5cc4016ff 317 SUPERFAMILY SSF53850 99 297 3.26E-20 T 06-07-2017 LK06_RS05230 340f16d04f943567ac8e336d3a1cf850 233 Gene3D G3DSA:1.20.120.530 86 220 2.7E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS05230 340f16d04f943567ac8e336d3a1cf850 233 SMART SM00345 12 70 2.9E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05230 340f16d04f943567ac8e336d3a1cf850 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 70 1.9E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05230 340f16d04f943567ac8e336d3a1cf850 233 SMART SM00895 99 223 6.0E-13 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS05230 340f16d04f943567ac8e336d3a1cf850 233 Pfam PF07729 FCD domain 100 219 2.0E-18 T 06-07-2017 IPR011711 GntR, C-terminal LK06_RS05230 340f16d04f943567ac8e336d3a1cf850 233 SUPERFAMILY SSF48008 96 224 1.02E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal LK06_RS05230 340f16d04f943567ac8e336d3a1cf850 233 SUPERFAMILY SSF46785 5 74 4.87E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05230 340f16d04f943567ac8e336d3a1cf850 233 Gene3D G3DSA:1.10.10.10 5 72 2.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11050 58ec5f47b83c7c60d8918cba8f2892e4 285 SUPERFAMILY SSF56529 68 283 1.31E-72 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS11050 58ec5f47b83c7c60d8918cba8f2892e4 285 Gene3D G3DSA:3.90.850.10 68 283 6.4E-82 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS11050 58ec5f47b83c7c60d8918cba8f2892e4 285 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 281 1.9E-66 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 LK06_RS24290 705f28f144cc59bec93ed8e3d40f311d 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 55 19.072 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24290 705f28f144cc59bec93ed8e3d40f311d 57 Pfam PF01783 Ribosomal L32p protein family 2 56 2.1E-25 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24290 705f28f144cc59bec93ed8e3d40f311d 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 5.2E-26 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS24290 705f28f144cc59bec93ed8e3d40f311d 57 SUPERFAMILY SSF57829 2 56 5.19E-21 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 LK06_RS23940 15b78a8546b90513d51380527e0c813a 332 Pfam PF00248 Aldo/keto reductase family 16 323 4.1E-59 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS23940 15b78a8546b90513d51380527e0c813a 332 SUPERFAMILY SSF51430 2 324 7.86E-83 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS23940 15b78a8546b90513d51380527e0c813a 332 Gene3D G3DSA:3.20.20.100 2 324 5.2E-105 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS01130 b3b0d193e687306bd0b760b843c96ec8 402 SUPERFAMILY SSF88713 71 111 3.89E-24 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS01130 b3b0d193e687306bd0b760b843c96ec8 402 SUPERFAMILY SSF88713 141 373 3.89E-24 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS01130 b3b0d193e687306bd0b760b843c96ec8 402 Gene3D G3DSA:3.20.20.370 53 373 8.3E-10 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS27080 0d6cee1e3709f93de08320dafcdd7131 394 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 199 381 1.5E-22 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS27080 0d6cee1e3709f93de08320dafcdd7131 394 SUPERFAMILY SSF52266 195 390 6.11E-45 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS27080 0d6cee1e3709f93de08320dafcdd7131 394 Gene3D G3DSA:3.40.50.1110 197 391 3.2E-34 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS26705 4ea5c92af95cb8fee473cbe9619019be 367 Gene3D G3DSA:3.40.50.300 31 227 5.1E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26705 4ea5c92af95cb8fee473cbe9619019be 367 SUPERFAMILY SSF52540 101 275 1.3E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26705 4ea5c92af95cb8fee473cbe9619019be 367 Pfam PF03969 AFG1-like ATPase 258 358 1.5E-14 T 06-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 LK06_RS26705 4ea5c92af95cb8fee473cbe9619019be 367 Pfam PF03969 AFG1-like ATPase 57 245 2.8E-41 T 06-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 LK06_RS06550 ca16ea452efa4ee880ea6f1436700c4d 344 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 299 3.5E-82 T 06-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA LK06_RS06550 ca16ea452efa4ee880ea6f1436700c4d 344 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 300 2.8E-94 T 06-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA LK06_RS31770 69dc45dbad3e5f780c0bbfba775e7930 181 SUPERFAMILY SSF53901 12 155 4.97E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS12855 ab257bb6ba0969de48ce41ddc18cdd56 387 SUPERFAMILY SSF52777 16 151 4.67E-8 T 06-07-2017 LK06_RS01955 619baff00b9981aa6d3ec7daa87acb69 435 Pfam PF01757 Acyltransferase family 64 406 5.5E-17 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 LK06_RS02755 228cca27e2ab83d11badd41cdda53775 75 Gene3D G3DSA:1.10.1200.10 3 72 8.8E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02755 228cca27e2ab83d11badd41cdda53775 75 Pfam PF00550 Phosphopantetheine attachment site 3 68 2.9E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS02755 228cca27e2ab83d11badd41cdda53775 75 SUPERFAMILY SSF47336 2 72 1.57E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS20635 96751ea899a3aedcd7bc27b9173235c3 273 SUPERFAMILY SSF56281 188 236 2.62E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS20635 96751ea899a3aedcd7bc27b9173235c3 273 SUPERFAMILY SSF56281 19 160 2.62E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS20635 96751ea899a3aedcd7bc27b9173235c3 273 Pfam PF00753 Metallo-beta-lactamase superfamily 25 92 2.0E-6 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS20635 96751ea899a3aedcd7bc27b9173235c3 273 SMART SM00849 26 224 7.5E-11 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS20635 96751ea899a3aedcd7bc27b9173235c3 273 Gene3D G3DSA:3.60.15.10 5 229 7.0E-30 T 06-07-2017 IPR001279 Metallo-beta-lactamase LK06_RS29210 7062839f0a86126c74ed5fcd24a5439b 256 SUPERFAMILY SSF53474 14 219 5.36E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS29210 7062839f0a86126c74ed5fcd24a5439b 256 Pfam PF00975 Thioesterase domain 20 219 3.6E-19 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS29210 7062839f0a86126c74ed5fcd24a5439b 256 Gene3D G3DSA:3.40.50.1820 166 219 7.2E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS29210 7062839f0a86126c74ed5fcd24a5439b 256 Gene3D G3DSA:3.40.50.1820 5 125 7.2E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS29020 9723f924b36ca325f8231f1c64a46154 204 Pfam PF13346 ABC-2 family transporter protein 24 190 4.6E-10 T 06-07-2017 IPR025699 ABC-2 membrane transporter-like LK06_RS15225 82d3a0723d6a570bc65f9532a4f84a8b 191 SUPERFAMILY SSF69118 11 179 1.05E-16 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS15225 82d3a0723d6a570bc65f9532a4f84a8b 191 Gene3D G3DSA:1.20.1290.10 151 177 5.3E-11 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS15225 82d3a0723d6a570bc65f9532a4f84a8b 191 Gene3D G3DSA:1.20.1290.10 10 101 5.3E-11 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 LK06_RS19980 a6b41b4635f6b2c37ed8de23fb2a2215 460 SUPERFAMILY SSF51905 263 347 6.17E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19980 a6b41b4635f6b2c37ed8de23fb2a2215 460 SUPERFAMILY SSF51905 5 175 6.17E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19980 a6b41b4635f6b2c37ed8de23fb2a2215 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.0E-7 T 06-07-2017 LK06_RS19980 a6b41b4635f6b2c37ed8de23fb2a2215 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 3.0E-7 T 06-07-2017 LK06_RS19980 a6b41b4635f6b2c37ed8de23fb2a2215 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 3.0E-7 T 06-07-2017 LK06_RS19980 a6b41b4635f6b2c37ed8de23fb2a2215 460 SUPERFAMILY SSF51905 153 268 1.62E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19980 a6b41b4635f6b2c37ed8de23fb2a2215 460 Gene3D G3DSA:3.50.50.60 6 112 1.7E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19980 a6b41b4635f6b2c37ed8de23fb2a2215 460 Gene3D G3DSA:3.50.50.60 270 348 1.7E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19980 a6b41b4635f6b2c37ed8de23fb2a2215 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 336 2.3E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS19980 a6b41b4635f6b2c37ed8de23fb2a2215 460 Gene3D G3DSA:3.50.50.60 113 269 2.0E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS22350 35bf438085b44ccc8d77f12c695abcf8 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 4.4E-24 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 LK06_RS22350 35bf438085b44ccc8d77f12c695abcf8 107 SUPERFAMILY SSF103481 6 105 3.92E-17 T 06-07-2017 LK06_RS15120 6fbcf2aa0c77ab774776db6f1ad6d8c9 226 Gene3D G3DSA:2.40.440.10 155 220 1.9E-4 T 06-07-2017 LK06_RS15120 6fbcf2aa0c77ab774776db6f1ad6d8c9 226 Gene3D G3DSA:2.40.440.10 45 93 1.9E-4 T 06-07-2017 LK06_RS07225 88040d7c5a39433690c3326ccab04764 366 Gene3D G3DSA:2.30.30.60 193 241 4.8E-12 T 06-07-2017 LK06_RS07225 88040d7c5a39433690c3326ccab04764 366 SUPERFAMILY SSF50182 177 242 1.67E-16 T 06-07-2017 IPR010920 LSM domain LK06_RS07225 88040d7c5a39433690c3326ccab04764 366 Pfam PF00924 Mechanosensitive ion channel 140 327 1.3E-32 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 LK06_RS12985 f65faec82c66112f84cf23f904f376bb 202 SUPERFAMILY SSF51338 9 51 2.85E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 LK06_RS30195 2d5c280c3c0fb29c0f5d9260ff1f8c8d 267 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 10 233 7.9E-108 T 06-07-2017 IPR022488 Polyphosphate kinase-2-related LK06_RS30195 2d5c280c3c0fb29c0f5d9260ff1f8c8d 267 SUPERFAMILY SSF52540 40 228 5.33E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30195 2d5c280c3c0fb29c0f5d9260ff1f8c8d 267 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 10 233 1.4E-114 T 06-07-2017 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 LK06_RS30195 2d5c280c3c0fb29c0f5d9260ff1f8c8d 267 PIRSF PIRSF028756 1 264 3.2E-126 T 06-07-2017 IPR016898 Polyphosphate kinase 2 LK06_RS30195 2d5c280c3c0fb29c0f5d9260ff1f8c8d 267 Gene3D G3DSA:3.40.50.300 7 244 1.3E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18415 70899fbc52db43dff04425717abd4fc3 684 Gene3D G3DSA:3.40.50.300 382 514 6.0E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18415 70899fbc52db43dff04425717abd4fc3 684 Gene3D G3DSA:3.40.50.300 185 247 6.0E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18415 70899fbc52db43dff04425717abd4fc3 684 SUPERFAMILY SSF52540 178 257 1.34E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18415 70899fbc52db43dff04425717abd4fc3 684 SUPERFAMILY SSF52540 399 677 1.34E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18415 70899fbc52db43dff04425717abd4fc3 684 Pfam PF13538 UvrD-like helicase C-terminal domain 629 672 1.5E-6 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain LK06_RS18415 70899fbc52db43dff04425717abd4fc3 684 Gene3D G3DSA:3.40.50.300 522 679 1.2E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18415 70899fbc52db43dff04425717abd4fc3 684 Pfam PF13245 Part of AAA domain 193 257 2.0E-13 T 06-07-2017 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 376 386 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 528 2.3E-30 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 4.1E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 341 347 4.1E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 4.1E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 4.1E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 4.1E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 371 383 4.1E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 Gene3D G3DSA:3.50.50.60 19 252 6.1E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 SUPERFAMILY SSF51905 290 351 6.37E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 SUPERFAMILY SSF51905 24 253 6.37E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS20180 f76b0cace0ca3790c387564cabd1a61c 568 Pfam PF01266 FAD dependent oxidoreductase 24 377 8.4E-50 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LK06_RS04685 5d07d29979449fdb7f9098582036156c 263 SUPERFAMILY SSF143631 12 260 2.35E-56 T 06-07-2017 IPR003374 ApbE-like domain LK06_RS04685 5d07d29979449fdb7f9098582036156c 263 Pfam PF02424 ApbE family 18 97 6.0E-9 T 06-07-2017 IPR024932 Flavin transferase ApbE GO:0017013 LK06_RS04685 5d07d29979449fdb7f9098582036156c 263 Pfam PF02424 ApbE family 103 242 1.2E-32 T 06-07-2017 IPR024932 Flavin transferase ApbE GO:0017013 LK06_RS31215 995bd9e384a415c65fc78dd6eab461ad 301 SUPERFAMILY SSF51735 1 292 5.45E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31215 995bd9e384a415c65fc78dd6eab461ad 301 Gene3D G3DSA:3.90.25.10 196 292 1.2E-16 T 06-07-2017 LK06_RS31215 995bd9e384a415c65fc78dd6eab461ad 301 Gene3D G3DSA:3.40.50.720 1 195 1.9E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31215 995bd9e384a415c65fc78dd6eab461ad 301 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 214 1.9E-31 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS06740 7a9ae05f9380df36330dcb3cbf794974 264 Pfam PF13489 Methyltransferase domain 35 198 2.3E-11 T 06-07-2017 LK06_RS06740 7a9ae05f9380df36330dcb3cbf794974 264 Gene3D G3DSA:3.40.50.150 20 203 4.1E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS06740 7a9ae05f9380df36330dcb3cbf794974 264 SUPERFAMILY SSF53335 20 199 1.13E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS02815 c0ae8bb58088758592957f34cfeb12c6 489 Gene3D G3DSA:3.90.79.10 48 176 2.5E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS02815 c0ae8bb58088758592957f34cfeb12c6 489 SUPERFAMILY SSF55811 40 177 3.38E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS02815 c0ae8bb58088758592957f34cfeb12c6 489 Gene3D G3DSA:3.90.79.10 192 321 6.1E-10 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS02815 c0ae8bb58088758592957f34cfeb12c6 489 Pfam PF00293 NUDIX domain 48 173 1.1E-14 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS02815 c0ae8bb58088758592957f34cfeb12c6 489 Pfam PF00293 NUDIX domain 354 468 2.9E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS02815 c0ae8bb58088758592957f34cfeb12c6 489 SUPERFAMILY SSF55811 193 323 2.17E-11 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS02815 c0ae8bb58088758592957f34cfeb12c6 489 Gene3D G3DSA:3.90.79.10 353 478 6.7E-19 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS02815 c0ae8bb58088758592957f34cfeb12c6 489 SUPERFAMILY SSF55811 352 479 4.87E-19 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS02190 80ae0414a6c2cdd660b1419b39ccf424 157 SUPERFAMILY SSF55811 8 150 2.17E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS02190 80ae0414a6c2cdd660b1419b39ccf424 157 Pfam PF00293 NUDIX domain 7 141 4.7E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS02190 80ae0414a6c2cdd660b1419b39ccf424 157 ProSitePatterns PS00893 Nudix box signature. 47 68 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LK06_RS02190 80ae0414a6c2cdd660b1419b39ccf424 157 Gene3D G3DSA:3.90.79.10 7 145 3.6E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS05270 6656eb43bd8a3c3dc9b381fd9db659db 130 Pfam PF02656 Domain of unknown function (DUF202) 27 92 2.3E-14 T 06-07-2017 IPR003807 Domain of unknown function DUF202 LK06_RS22280 e57e41bc3c8043bf41eecb4071309d07 173 Pfam PF00293 NUDIX domain 44 155 1.8E-11 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS22280 e57e41bc3c8043bf41eecb4071309d07 173 Gene3D G3DSA:3.90.79.10 43 160 1.1E-17 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS22280 e57e41bc3c8043bf41eecb4071309d07 173 SUPERFAMILY SSF55811 43 168 8.26E-19 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS08775 e040aa946a81581ae6ff9b0a9a850d1a 192 Gene3D G3DSA:2.60.60.30 18 184 1.4E-72 T 06-07-2017 LK06_RS08775 e040aa946a81581ae6ff9b0a9a850d1a 192 Pfam PF02342 TerD domain 1 187 1.7E-83 T 06-07-2017 IPR003325 TerD domain GO:0006950 LK06_RS16905 98790f84e84f940fedc089c999951019 158 Gene3D G3DSA:3.40.50.450 40 153 2.0E-6 T 06-07-2017 LK06_RS16905 98790f84e84f940fedc089c999951019 158 SUPERFAMILY SSF102405 2 154 9.16E-13 T 06-07-2017 LK06_RS15950 367f9bf394df7f7f7e60b74c850a739c 420 SUPERFAMILY SSF103473 17 414 9.16E-24 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS15950 367f9bf394df7f7f7e60b74c850a739c 420 Pfam PF07690 Major Facilitator Superfamily 43 379 2.8E-14 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS15950 367f9bf394df7f7f7e60b74c850a739c 420 Gene3D G3DSA:1.20.1250.20 237 410 3.1E-7 T 06-07-2017 LK06_RS15950 367f9bf394df7f7f7e60b74c850a739c 420 Gene3D G3DSA:1.20.1250.20 33 195 2.1E-9 T 06-07-2017 LK06_RS18965 cc26f4ee3cdf56d62354bf3f4b920dee 410 Pfam PF04909 Amidohydrolase 110 400 5.0E-40 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS18965 cc26f4ee3cdf56d62354bf3f4b920dee 410 Gene3D G3DSA:3.20.20.140 88 401 9.5E-65 T 06-07-2017 LK06_RS18965 cc26f4ee3cdf56d62354bf3f4b920dee 410 Gene3D G3DSA:3.20.20.140 8 36 9.5E-65 T 06-07-2017 LK06_RS18965 cc26f4ee3cdf56d62354bf3f4b920dee 410 SUPERFAMILY SSF51556 8 36 1.13E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS18965 cc26f4ee3cdf56d62354bf3f4b920dee 410 SUPERFAMILY SSF51556 101 400 1.13E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS04475 51b2d2bbd0dc13763358868f3d60e579 151 TIGRFAM TIGR02611 TIGR02611: TIGR02611 family protein 29 144 1.2E-39 T 06-07-2017 IPR013434 Conserved hypothetical protein CHP02611 LK06_RS04475 51b2d2bbd0dc13763358868f3d60e579 151 Pfam PF09656 Putative transmembrane protein (PGPGW) 49 101 1.9E-21 T 06-07-2017 IPR019099 Uncharacterised protein family PGPGW, transmembrane LK06_RS02280 9be0490755e3d638255ff6108ba30741 239 SMART SM00563 35 154 1.4E-38 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS02280 9be0490755e3d638255ff6108ba30741 239 SUPERFAMILY SSF69593 2 216 2.22E-53 T 06-07-2017 LK06_RS02280 9be0490755e3d638255ff6108ba30741 239 Gene3D G3DSA:3.40.1130.10 3 208 1.4E-34 T 06-07-2017 LK06_RS02280 9be0490755e3d638255ff6108ba30741 239 Pfam PF01553 Acyltransferase 21 151 1.2E-24 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 LK06_RS14590 b73c1f2687665e671903f26842413323 310 Gene3D G3DSA:3.40.50.1820 18 305 2.5E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS14590 b73c1f2687665e671903f26842413323 310 SUPERFAMILY SSF53474 12 304 1.17E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS14590 b73c1f2687665e671903f26842413323 310 Pfam PF00326 Prolyl oligopeptidase family 130 287 2.6E-6 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 LK06_RS31790 356ddbf6684fb583a18f8f75eaa56b6d 307 Gene3D G3DSA:2.60.120.620 22 267 7.2E-48 T 06-07-2017 LK06_RS31790 356ddbf6684fb583a18f8f75eaa56b6d 307 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 32 253 3.0E-20 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase LK06_RS31790 356ddbf6684fb583a18f8f75eaa56b6d 307 SUPERFAMILY SSF51197 22 269 4.21E-46 T 06-07-2017 LK06_RS09825 0882069f034b292d007856f821193808 1421 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 668 1067 9.1E-154 T 06-07-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 LK06_RS09825 0882069f034b292d007856f821193808 1421 Pfam PF10150 Ribonuclease E/G family 772 1041 8.9E-108 T 06-07-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 LK06_RS09825 0882069f034b292d007856f821193808 1421 SMART SM00316 691 770 1.6E-4 T 06-07-2017 IPR022967 RNA-binding domain, S1 LK06_RS09825 0882069f034b292d007856f821193808 1421 SUPERFAMILY SSF50249 693 776 4.91E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS09825 0882069f034b292d007856f821193808 1421 Gene3D G3DSA:2.40.50.140 685 776 3.2E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS08060 35a2b124769887a451b143715ad2a67e 166 Pfam PF12688 Tetratrico peptide repeat 45 161 5.9E-56 T 06-07-2017 LK06_RS15250 3c21842582b86dd1455760bb35a926f4 387 SUPERFAMILY SSF81606 156 370 1.75E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15250 3c21842582b86dd1455760bb35a926f4 387 SMART SM00331 143 371 1.6E-21 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS15250 3c21842582b86dd1455760bb35a926f4 387 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 169 371 7.7E-40 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS06240 5261450afea45aa31a0fb308950010de 1214 Pfam PF02514 CobN/Magnesium Chelatase 97 1194 0.0 T 06-07-2017 IPR003672 CobN/magnesium chelatase GO:0009058 LK06_RS06240 5261450afea45aa31a0fb308950010de 1214 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 37 1205 0.0 T 06-07-2017 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 LK06_RS14075 7cc0fdb76cbc8f2a110074bc5ddec348 328 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 8 223 3.1E-12 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain LK06_RS14075 7cc0fdb76cbc8f2a110074bc5ddec348 328 Gene3D G3DSA:3.40.50.300 119 250 4.5E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14075 7cc0fdb76cbc8f2a110074bc5ddec348 328 Gene3D G3DSA:3.40.50.300 2 77 4.5E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14075 7cc0fdb76cbc8f2a110074bc5ddec348 328 SUPERFAMILY SSF52540 101 246 1.09E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS14075 7cc0fdb76cbc8f2a110074bc5ddec348 328 SUPERFAMILY SSF52540 3 53 1.09E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25035 db804248f318725efe86bbc5756c6f9f 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 61 1.0E-31 T 06-07-2017 IPR021408 Protein of unknown function DUF3046 LK06_RS01100 423f11d3c4cb33fe7bf5317d095852a0 131 Gene3D G3DSA:2.60.120.10 3 110 2.8E-33 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS01100 423f11d3c4cb33fe7bf5317d095852a0 131 Pfam PF07883 Cupin domain 34 97 7.7E-12 T 06-07-2017 IPR013096 Cupin 2, conserved barrel LK06_RS01100 423f11d3c4cb33fe7bf5317d095852a0 131 SUPERFAMILY SSF51182 2 113 2.61E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS31795 b8717d01766e9d76b2ce52a1332b95e1 327 Pfam PF00676 Dehydrogenase E1 component 15 273 1.4E-70 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 LK06_RS31795 b8717d01766e9d76b2ce52a1332b95e1 327 SUPERFAMILY SSF52518 14 320 1.05E-82 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS31795 b8717d01766e9d76b2ce52a1332b95e1 327 Gene3D G3DSA:3.40.50.970 15 317 6.8E-103 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS00380 431ca632e72e30c5dee05011bd242827 319 SUPERFAMILY SSF161098 92 298 7.98E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS00380 431ca632e72e30c5dee05011bd242827 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 315 1.2E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS00380 431ca632e72e30c5dee05011bd242827 319 Gene3D G3DSA:1.10.3720.10 89 312 2.3E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS17135 045ccd05b340f1db30b3743912511a92 228 Gene3D G3DSA:1.10.260.40 23 88 8.6E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS17135 045ccd05b340f1db30b3743912511a92 228 SUPERFAMILY SSF47413 21 92 1.04E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS08760 c890ca5907809d3bc09506bc00708417 243 Pfam PF02342 TerD domain 1 174 9.9E-47 T 06-07-2017 IPR003325 TerD domain GO:0006950 LK06_RS08760 c890ca5907809d3bc09506bc00708417 243 Gene3D G3DSA:2.60.60.30 17 172 1.7E-32 T 06-07-2017 LK06_RS31950 f29a996ee0e671d1f37f4b747fa19349 855 Pfam PF04738 Lantibiotic dehydratase, C terminus 703 763 4.5E-7 T 06-07-2017 IPR006827 Lantibiotic dehydratase, C-terminal LK06_RS02990 474c255b0326d07316609b170248f03a 119 SUPERFAMILY SSF46785 13 99 9.87E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02990 474c255b0326d07316609b170248f03a 119 SMART SM00418 24 102 2.1E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS02990 474c255b0326d07316609b170248f03a 119 Gene3D G3DSA:1.10.10.10 11 106 1.9E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS02990 474c255b0326d07316609b170248f03a 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 26 41 5.7E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS02990 474c255b0326d07316609b170248f03a 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 5.7E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS02990 474c255b0326d07316609b170248f03a 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 5.7E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS02990 474c255b0326d07316609b170248f03a 119 Pfam PF01022 Bacterial regulatory protein, arsR family 31 76 8.9E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LK06_RS06400 f53944ba447857bb0399acdc0203c8f6 400 Pfam PF02342 TerD domain 20 158 8.6E-30 T 06-07-2017 IPR003325 TerD domain GO:0006950 LK06_RS06400 f53944ba447857bb0399acdc0203c8f6 400 Pfam PF02342 TerD domain 218 385 3.2E-40 T 06-07-2017 IPR003325 TerD domain GO:0006950 LK06_RS06400 f53944ba447857bb0399acdc0203c8f6 400 Gene3D G3DSA:2.60.60.30 20 156 5.2E-29 T 06-07-2017 LK06_RS06400 f53944ba447857bb0399acdc0203c8f6 400 Gene3D G3DSA:2.60.60.30 236 389 2.6E-50 T 06-07-2017 LK06_RS27960 e79ed3daf45ebb7c1dfe260ad4963bfd 271 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 26 198 7.3E-33 T 06-07-2017 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 LK06_RS27960 e79ed3daf45ebb7c1dfe260ad4963bfd 271 Pfam PF01066 CDP-alcohol phosphatidyltransferase 21 100 1.1E-11 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS27960 e79ed3daf45ebb7c1dfe260ad4963bfd 271 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 79 100 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS03930 bb97961d187027053bd73a64a5aef330 282 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 282 31.819 T 06-07-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 LK06_RS03930 bb97961d187027053bd73a64a5aef330 282 Pfam PF08029 HisG, C-terminal domain 207 278 9.4E-26 T 06-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 LK06_RS03930 bb97961d187027053bd73a64a5aef330 282 Pfam PF01634 ATP phosphoribosyltransferase 49 203 2.1E-39 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 LK06_RS03930 bb97961d187027053bd73a64a5aef330 282 SUPERFAMILY SSF54913 210 281 3.89E-21 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta LK06_RS03930 bb97961d187027053bd73a64a5aef330 282 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 191 281 1.5E-29 T 06-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 LK06_RS03930 bb97961d187027053bd73a64a5aef330 282 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 2.6E-49 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 LK06_RS03930 bb97961d187027053bd73a64a5aef330 282 Gene3D G3DSA:3.30.70.120 210 281 8.8E-29 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal LK06_RS03930 bb97961d187027053bd73a64a5aef330 282 SUPERFAMILY SSF53850 1 208 1.14E-58 T 06-07-2017 LK06_RS03930 bb97961d187027053bd73a64a5aef330 282 Gene3D G3DSA:3.40.190.10 1 107 5.7E-33 T 06-07-2017 LK06_RS03930 bb97961d187027053bd73a64a5aef330 282 Gene3D G3DSA:3.40.190.10 108 173 1.6E-22 T 06-07-2017 LK06_RS24720 ae7bdd156dd84f621590bdc736de753c 176 SUPERFAMILY SSF55729 12 169 4.82E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS24720 ae7bdd156dd84f621590bdc736de753c 176 Gene3D G3DSA:3.40.630.30 44 173 1.3E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS24720 ae7bdd156dd84f621590bdc736de753c 176 Pfam PF13508 Acetyltransferase (GNAT) domain 57 149 6.4E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS03450 d3d532b0f10ec675a070d7f568b65487 273 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 77 3.4E-19 T 06-07-2017 IPR025161 Putative transposase IS4/IS5 family LK06_RS03450 d3d532b0f10ec675a070d7f568b65487 273 Pfam PF01609 Transposase DDE domain 97 225 6.6E-17 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS23165 d6f5439e1b697cd446907f65cbf3aad6 312 Pfam PF01609 Transposase DDE domain 170 299 2.0E-9 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS23165 d6f5439e1b697cd446907f65cbf3aad6 312 Pfam PF13808 DDE_Tnp_1-associated 37 125 3.0E-15 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS26730 cc52a1e0cba5bf13a0257f64dcbee704 164 Pfam PF06271 RDD family 17 143 1.1E-15 T 06-07-2017 IPR010432 RDD LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 SUPERFAMILY SSF51905 284 378 2.7E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 SUPERFAMILY SSF51905 7 167 2.7E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 5.7E-15 T 06-07-2017 LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 5.7E-15 T 06-07-2017 LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 5.7E-15 T 06-07-2017 LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 5.7E-15 T 06-07-2017 LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 SUPERFAMILY SSF54373 171 279 1.88E-15 T 06-07-2017 LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 Pfam PF01494 FAD binding domain 272 335 5.5E-5 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 Gene3D G3DSA:3.50.50.60 7 63 1.2E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 Gene3D G3DSA:3.50.50.60 285 364 1.2E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS26185 8fbfc25cdc3b37dd2f9e87146a9aefe1 400 Gene3D G3DSA:3.50.50.60 95 172 1.2E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS15795 300cfc4da59bcde06520351b709541ac 60 Gene3D G3DSA:2.10.230.10 6 49 0.001 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 LK06_RS05245 ce5be226cde802fce660908705117d47 209 Gene3D G3DSA:1.20.950.20 13 207 4.7E-45 T 06-07-2017 LK06_RS05245 ce5be226cde802fce660908705117d47 209 Pfam PF01292 Prokaryotic cytochrome b561 18 181 2.8E-12 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 LK06_RS05245 ce5be226cde802fce660908705117d47 209 SUPERFAMILY SSF81342 13 207 5.96E-23 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 LK06_RS28830 8118df7341c09771097707fe3c62cefb 199 Gene3D G3DSA:3.40.50.300 11 184 5.1E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28830 8118df7341c09771097707fe3c62cefb 199 SUPERFAMILY SSF52540 13 168 3.82E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28830 8118df7341c09771097707fe3c62cefb 199 Pfam PF03029 Conserved hypothetical ATP binding protein 18 185 2.4E-27 T 06-07-2017 IPR004130 GPN-loop GTPase LK06_RS24695 caa3f36d3c41652b8fe2158b6f3db950 95 Pfam PF09851 Short C-terminal domain 67 94 6.0E-9 T 06-07-2017 IPR018649 SHOCT domain LK06_RS28995 b118f744f8f5876d08c4d0f6b77a4f8c 305 SUPERFAMILY SSF161098 65 291 5.23E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS28995 b118f744f8f5876d08c4d0f6b77a4f8c 305 Gene3D G3DSA:1.10.3720.10 73 301 4.5E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS28995 b118f744f8f5876d08c4d0f6b77a4f8c 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 297 7.7E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS18285 b614487c71a10aada5f7c48a900a41c1 427 TIGRFAM TIGR00260 thrC: threonine synthase 71 402 3.8E-83 T 06-07-2017 IPR004450 Threonine synthase-like LK06_RS18285 b614487c71a10aada5f7c48a900a41c1 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 396 1.4E-65 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS18285 b614487c71a10aada5f7c48a900a41c1 427 Gene3D G3DSA:3.40.50.1100 126 210 4.2E-28 T 06-07-2017 LK06_RS18285 b614487c71a10aada5f7c48a900a41c1 427 Gene3D G3DSA:3.40.50.1100 211 406 4.2E-37 T 06-07-2017 LK06_RS18285 b614487c71a10aada5f7c48a900a41c1 427 SUPERFAMILY SSF53686 18 410 1.7E-90 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS23980 6beb45946f58fd1d0b0c2e2ac5a3a76b 196 SUPERFAMILY SSF46689 4 65 1.49E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS23980 6beb45946f58fd1d0b0c2e2ac5a3a76b 196 SUPERFAMILY SSF48498 77 181 5.34E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS23980 6beb45946f58fd1d0b0c2e2ac5a3a76b 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 4.8E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23980 6beb45946f58fd1d0b0c2e2ac5a3a76b 196 Gene3D G3DSA:1.10.357.10 4 189 2.6E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS23980 6beb45946f58fd1d0b0c2e2ac5a3a76b 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS23980 6beb45946f58fd1d0b0c2e2ac5a3a76b 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS28295 5578d9c7ae8e2616a98e131846696cfa 253 Pfam PF01066 CDP-alcohol phosphatidyltransferase 69 136 1.5E-8 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS28295 5578d9c7ae8e2616a98e131846696cfa 253 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 114 136 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS21880 634d75eb52b2a2ea2de48608c6713346 329 Gene3D G3DSA:1.10.3720.10 108 325 4.6E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21880 634d75eb52b2a2ea2de48608c6713346 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 328 6.5E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21880 634d75eb52b2a2ea2de48608c6713346 329 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 67 1.9E-11 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LK06_RS21880 634d75eb52b2a2ea2de48608c6713346 329 SUPERFAMILY SSF161098 110 314 4.32E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21990 b021c57641bcbd192cbf612feef08da0 252 Gene3D G3DSA:3.40.50.450 53 248 2.5E-63 T 06-07-2017 LK06_RS21990 b021c57641bcbd192cbf612feef08da0 252 SUPERFAMILY SSF102405 44 245 8.85E-64 T 06-07-2017 LK06_RS21990 b021c57641bcbd192cbf612feef08da0 252 Pfam PF03641 Possible lysine decarboxylase 116 244 8.3E-33 T 06-07-2017 IPR031100 LOG family LK06_RS21990 b021c57641bcbd192cbf612feef08da0 252 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 74 247 2.0E-41 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG LK06_RS09805 06141dfb2203effeab3215696d4c51c2 84 Pfam PF01016 Ribosomal L27 protein 2 80 7.3E-36 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09805 06141dfb2203effeab3215696d4c51c2 84 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.9E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09805 06141dfb2203effeab3215696d4c51c2 84 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.9E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09805 06141dfb2203effeab3215696d4c51c2 84 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.9E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09805 06141dfb2203effeab3215696d4c51c2 84 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 72 1.0E-17 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09805 06141dfb2203effeab3215696d4c51c2 84 Gene3D G3DSA:2.40.50.100 20 82 2.5E-28 T 06-07-2017 LK06_RS09805 06141dfb2203effeab3215696d4c51c2 84 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.83 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09805 06141dfb2203effeab3215696d4c51c2 84 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 06-07-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LK06_RS09805 06141dfb2203effeab3215696d4c51c2 84 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 7.1E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS09805 06141dfb2203effeab3215696d4c51c2 84 SUPERFAMILY SSF110324 2 81 8.37E-31 T 06-07-2017 LK06_RS10570 c4e46234af375f9bd04f9ec794e4aedd 239 Pfam PF10935 Protein of unknown function (DUF2637) 10 95 3.0E-8 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 LK06_RS06040 14bb71a8f0c7af2e7dbad6b1b2c0f0c3 136 Pfam PF11298 Protein of unknown function (DUF3099) 13 81 5.0E-23 T 06-07-2017 IPR021449 Protein of unknown function DUF3099 LK06_RS22810 1be44f227f1ea23e982461ce8f6528d9 201 SMART SM00014 62 175 9.5E-16 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS22810 1be44f227f1ea23e982461ce8f6528d9 201 Pfam PF01569 PAP2 superfamily 67 180 2.5E-22 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS22810 1be44f227f1ea23e982461ce8f6528d9 201 Gene3D G3DSA:1.20.144.10 22 181 1.7E-30 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS22810 1be44f227f1ea23e982461ce8f6528d9 201 SUPERFAMILY SSF48317 21 182 2.88E-33 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS06395 b52a30c227b8874dd01fe7ebf3628540 269 SUPERFAMILY SSF51735 1 232 5.07E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06395 b52a30c227b8874dd01fe7ebf3628540 269 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 169 5.1E-21 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 LK06_RS06395 b52a30c227b8874dd01fe7ebf3628540 269 Gene3D G3DSA:3.40.50.720 4 218 3.0E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS19635 86b3c7995ffbb05dd4d0aecf49e749af 91 Pfam PF08962 Domain of unknown function (DUF1876) 7 87 5.5E-29 T 06-07-2017 IPR015057 Protein of unknown function DUF1876 LK06_RS19635 86b3c7995ffbb05dd4d0aecf49e749af 91 SUPERFAMILY SSF143212 1 84 1.7E-26 T 06-07-2017 LK06_RS19635 86b3c7995ffbb05dd4d0aecf49e749af 91 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 2 80 1.0E-33 T 06-07-2017 IPR015057 Protein of unknown function DUF1876 LK06_RS30200 e6ec981153f53d344488b52f34c698bb 332 SUPERFAMILY SSF55469 4 81 1.44E-8 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS30200 e6ec981153f53d344488b52f34c698bb 332 Gene3D G3DSA:3.40.109.30 7 91 1.8E-11 T 06-07-2017 LK06_RS30200 e6ec981153f53d344488b52f34c698bb 332 Pfam PF00881 Nitroreductase family 122 307 8.0E-7 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 LK06_RS30200 e6ec981153f53d344488b52f34c698bb 332 Gene3D G3DSA:3.40.109.10 233 316 4.0E-15 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS30200 e6ec981153f53d344488b52f34c698bb 332 Gene3D G3DSA:3.40.109.10 112 174 4.0E-15 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS30200 e6ec981153f53d344488b52f34c698bb 332 SUPERFAMILY SSF55469 115 170 4.49E-12 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS30200 e6ec981153f53d344488b52f34c698bb 332 SUPERFAMILY SSF55469 228 319 4.49E-12 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS10715 d6e811973bee32b966b233bf60d78f4e 538 SUPERFAMILY SSF52096 240 520 6.69E-89 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS10715 d6e811973bee32b966b233bf60d78f4e 538 Gene3D G3DSA:3.90.226.10 35 278 1.0E-78 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS10715 d6e811973bee32b966b233bf60d78f4e 538 Gene3D G3DSA:3.90.226.10 283 533 8.8E-95 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS10715 d6e811973bee32b966b233bf60d78f4e 538 SUPERFAMILY SSF52096 28 272 4.23E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS10715 d6e811973bee32b966b233bf60d78f4e 538 Pfam PF01039 Carboxyl transferase domain 51 527 2.0E-152 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS11560 eb99da3b706d46bd58157ae632276c74 333 Pfam PF04087 Domain of unknown function (DUF389) 66 201 4.8E-28 T 06-07-2017 IPR005240 Protein of unknown function DUF389 LK06_RS13190 22bc243b012b756284b55bd8ad9640ba 70 SUPERFAMILY SSF56784 2 65 2.87E-10 T 06-07-2017 IPR023214 HAD-like domain LK06_RS13190 22bc243b012b756284b55bd8ad9640ba 70 Gene3D G3DSA:3.40.50.1000 2 64 3.4E-10 T 06-07-2017 IPR023214 HAD-like domain LK06_RS20240 dd01b4a85304b9bc8ec978c0a665c0cf 426 Gene3D G3DSA:2.60.40.10 319 418 2.1E-6 T 06-07-2017 IPR013783 Immunoglobulin-like fold LK06_RS21045 7d365acdaae57dc64d8615ea6edc8a1f 262 Pfam PF00975 Thioesterase domain 23 234 3.0E-51 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 LK06_RS21045 7d365acdaae57dc64d8615ea6edc8a1f 262 Gene3D G3DSA:3.40.50.1820 12 241 8.2E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS21045 7d365acdaae57dc64d8615ea6edc8a1f 262 SMART SM00824 Thioesterase 25 247 1.7E-4 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 LK06_RS21045 7d365acdaae57dc64d8615ea6edc8a1f 262 SUPERFAMILY SSF53474 7 245 3.74E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08905 98bcbfee58636189a0b609cc22513389 546 Gene3D G3DSA:3.90.1150.10 268 368 7.3E-21 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS08905 98bcbfee58636189a0b609cc22513389 546 Gene3D G3DSA:3.40.640.10 45 263 5.5E-50 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS08905 98bcbfee58636189a0b609cc22513389 546 Pfam PF00155 Aminotransferase class I and II 54 360 1.5E-24 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS08905 98bcbfee58636189a0b609cc22513389 546 SUPERFAMILY SSF53383 21 367 6.93E-57 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS31920 ccd90221225ce02d059185aa882e57d3 240 PIRSF PIRSF006648 1 237 7.1E-18 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS15625 8c23ea242567c3e6bf2f58f6eef89667 84 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 84 22.863 T 06-07-2017 IPR009619 Cell division protein CrgA LK06_RS15625 8c23ea242567c3e6bf2f58f6eef89667 84 Pfam PF06781 Uncharacterised protein family (UPF0233) 2 84 2.6E-29 T 06-07-2017 IPR009619 Cell division protein CrgA LK06_RS01445 bb4d7e932a2ad3020a692bb035a3c799 148 Pfam PF03779 SPW repeat 35 74 3.1E-10 T 06-07-2017 IPR005530 SPW repeat LK06_RS01445 bb4d7e932a2ad3020a692bb035a3c799 148 Pfam PF03779 SPW repeat 91 138 1.1E-7 T 06-07-2017 IPR005530 SPW repeat LK06_RS17775 f2e55076007757d88ffe8e9f2a87bbd1 114 Pfam PF10724 Protein of unknown function (DUF2516) 6 91 4.8E-27 T 06-07-2017 IPR019662 Protein of unknown function DUF2516 LK06_RS11865 9e7b26d4d725095a29aa11463fff5ea5 56 Pfam PF03966 Trm112p-like protein 7 43 9.5E-8 T 06-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 LK06_RS11865 9e7b26d4d725095a29aa11463fff5ea5 56 SUPERFAMILY SSF158997 1 54 8.11E-17 T 06-07-2017 LK06_RS11865 9e7b26d4d725095a29aa11463fff5ea5 56 Gene3D G3DSA:2.20.25.10 10 54 3.6E-20 T 06-07-2017 LK06_RS12665 a4d7193e4a4dc6aa30d8603b7d44a1c8 322 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 3 321 22.235 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12665 a4d7193e4a4dc6aa30d8603b7d44a1c8 322 Pfam PF00146 NADH dehydrogenase 11 314 3.6E-100 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS26460 4885e52164c7627e43eb9e485cb5ac8c 31 Pfam PF05593 RHS Repeat 2 29 1.5E-5 T 06-07-2017 IPR031325 RHS repeat LK06_RS26460 4885e52164c7627e43eb9e485cb5ac8c 31 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2 30 3.7E-6 T 06-07-2017 IPR006530 YD repeat LK06_RS06690 1c6f4dc5f211e05977e64212b413d04e 366 Pfam PF01699 Sodium/calcium exchanger protein 222 361 5.2E-14 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 LK06_RS06690 1c6f4dc5f211e05977e64212b413d04e 366 Pfam PF01699 Sodium/calcium exchanger protein 36 188 1.6E-13 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 LK06_RS16990 fb116ebe921cce441360d624caf1b16b 289 Pfam PF01061 ABC-2 type transporter 43 250 1.4E-16 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS00390 ffa3e0f515c61889de372ca55b39f7f8 415 Pfam PF00480 ROK family 127 382 2.1E-51 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LK06_RS00390 ffa3e0f515c61889de372ca55b39f7f8 415 SUPERFAMILY SSF53067 87 385 3.65E-52 T 06-07-2017 LK06_RS00390 ffa3e0f515c61889de372ca55b39f7f8 415 Gene3D G3DSA:1.10.10.10 20 80 4.2E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00390 ffa3e0f515c61889de372ca55b39f7f8 415 Gene3D G3DSA:3.30.420.40 86 223 6.3E-39 T 06-07-2017 LK06_RS00390 ffa3e0f515c61889de372ca55b39f7f8 415 SUPERFAMILY SSF46785 19 80 1.02E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00390 ffa3e0f515c61889de372ca55b39f7f8 415 Gene3D G3DSA:3.30.420.40 224 366 5.3E-42 T 06-07-2017 LK06_RS14650 02559319a8bd151ecab25be4b78ecc00 123 Pfam PF03330 Lytic transglycolase 22 118 8.0E-15 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain LK06_RS14650 02559319a8bd151ecab25be4b78ecc00 123 Gene3D G3DSA:2.40.40.10 22 121 1.6E-14 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain LK06_RS14650 02559319a8bd151ecab25be4b78ecc00 123 SUPERFAMILY SSF50685 12 122 1.92E-22 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain LK06_RS19740 43c2a362585a27d7fd3a0889bd53a765 563 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 51 460 2.5E-63 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS19740 43c2a362585a27d7fd3a0889bd53a765 563 Pfam PF00474 Sodium:solute symporter family 51 460 4.6E-45 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS07030 d02fe1f531b31d9d5d0e1c31ef5d076b 241 Gene3D G3DSA:3.40.50.410 39 154 2.4E-5 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS07030 d02fe1f531b31d9d5d0e1c31ef5d076b 241 Pfam PF10138 vWA found in TerF C terminus 37 238 3.0E-66 T 06-07-2017 IPR019303 vWA found in TerF C terminus LK06_RS07030 d02fe1f531b31d9d5d0e1c31ef5d076b 241 SUPERFAMILY SSF53300 37 188 1.14E-14 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS07030 d02fe1f531b31d9d5d0e1c31ef5d076b 241 SMART SM00327 36 210 4.6E-6 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS16480 b8e4e5fd7df115c0aaa26b7d4c90c389 388 PIRSF PIRSF000429 10 339 2.1E-17 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 LK06_RS16480 b8e4e5fd7df115c0aaa26b7d4c90c389 388 SUPERFAMILY SSF53901 11 237 1.75E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS16480 b8e4e5fd7df115c0aaa26b7d4c90c389 388 SUPERFAMILY SSF53901 242 376 7.52E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS16480 b8e4e5fd7df115c0aaa26b7d4c90c389 388 Gene3D G3DSA:3.40.47.10 19 119 6.4E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS16480 b8e4e5fd7df115c0aaa26b7d4c90c389 388 Gene3D G3DSA:3.40.47.10 207 234 6.4E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 LK06_RS14550 c4ac1b8c18a96a1a223ecfcc745efc68 281 Pfam PF00781 Diacylglycerol kinase catalytic domain 10 126 2.8E-6 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 LK06_RS14550 c4ac1b8c18a96a1a223ecfcc745efc68 281 SUPERFAMILY SSF111331 9 132 2.07E-12 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain LK06_RS09345 b316eca684072ee02816655ff18f33a6 228 Pfam PF00005 ABC transporter 22 171 6.2E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS09345 b316eca684072ee02816655ff18f33a6 228 Gene3D G3DSA:3.40.50.300 3 220 2.9E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09345 b316eca684072ee02816655ff18f33a6 228 SMART SM00382 31 219 1.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS09345 b316eca684072ee02816655ff18f33a6 228 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS09345 b316eca684072ee02816655ff18f33a6 228 SUPERFAMILY SSF52540 3 221 5.1E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27420 a606846ffd0d59bb7664d8a62aecfb91 455 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 345 365 - T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 LK06_RS27420 a606846ffd0d59bb7664d8a62aecfb91 455 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 10 428 1.5E-106 T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 LK06_RS27420 a606846ffd0d59bb7664d8a62aecfb91 455 Pfam PF00860 Permease family 15 397 1.8E-91 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS27420 a606846ffd0d59bb7664d8a62aecfb91 455 TIGRFAM TIGR03173 pbuX: xanthine permease 19 430 5.5E-153 T 06-07-2017 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 LK06_RS30795 8308fa657d4f97bd79bd87ffbf00a14e 154 SUPERFAMILY SSF55874 61 136 1.32E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23805 2809026e9afbb36a967ce991f65c837e 287 Pfam PF13622 Thioesterase-like superfamily 39 284 1.6E-41 T 06-07-2017 LK06_RS23805 2809026e9afbb36a967ce991f65c837e 287 SUPERFAMILY SSF54637 137 285 2.34E-10 T 06-07-2017 IPR029069 HotDog domain LK06_RS23805 2809026e9afbb36a967ce991f65c837e 287 SUPERFAMILY SSF54637 20 112 2.44E-9 T 06-07-2017 IPR029069 HotDog domain LK06_RS26910 f9a4a9836ec8f91d33445966f26ac6c0 183 SUPERFAMILY SSF160379 1 178 8.76E-52 T 06-07-2017 LK06_RS26910 f9a4a9836ec8f91d33445966f26ac6c0 183 Gene3D G3DSA:3.30.70.1280 1 88 3.0E-27 T 06-07-2017 LK06_RS26910 f9a4a9836ec8f91d33445966f26ac6c0 183 PIRSF PIRSF008502 1 181 8.1E-47 T 06-07-2017 IPR012545 Protein of unknown function DUF1697 LK06_RS26910 f9a4a9836ec8f91d33445966f26ac6c0 183 Pfam PF08002 Protein of unknown function (DUF1697) 1 137 1.9E-42 T 06-07-2017 IPR012545 Protein of unknown function DUF1697 LK06_RS16260 de569f07e72f5da7583bc67104633934 217 Pfam PF02630 SCO1/SenC 53 170 1.6E-23 T 06-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS16260 de569f07e72f5da7583bc67104633934 217 SUPERFAMILY SSF52833 53 214 7.48E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS16260 de569f07e72f5da7583bc67104633934 217 Gene3D G3DSA:3.40.30.10 11 215 3.5E-42 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS11310 81a311e53bf4f11971c71a6dacb544fc 215 Gene3D G3DSA:1.10.3720.10 11 201 3.1E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS11310 81a311e53bf4f11971c71a6dacb544fc 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 206 3.1E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS11310 81a311e53bf4f11971c71a6dacb544fc 215 SUPERFAMILY SSF161098 13 198 6.28E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS24170 be2f6e5a7851b113801857b4a88606eb 174 Pfam PF13826 Domain of unknown function (DUF4188) 18 140 3.1E-36 T 06-07-2017 IPR025444 Protein of unknown function DUF4188 LK06_RS05250 276d0d44f2eb313710716c5fbc7072c3 244 Pfam PF00174 Oxidoreductase molybdopterin binding domain 75 221 1.2E-37 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS05250 276d0d44f2eb313710716c5fbc7072c3 244 Gene3D G3DSA:3.90.420.10 73 230 6.0E-50 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS05250 276d0d44f2eb313710716c5fbc7072c3 244 SUPERFAMILY SSF56524 68 233 1.01E-52 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS18625 01cc39932e8e8f6eeeb5e3da7fc73d24 332 Pfam PF00892 EamA-like transporter family 183 314 4.7E-17 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS18625 01cc39932e8e8f6eeeb5e3da7fc73d24 332 SUPERFAMILY SSF103481 83 176 1.44E-5 T 06-07-2017 LK06_RS18625 01cc39932e8e8f6eeeb5e3da7fc73d24 332 SUPERFAMILY SSF103481 219 318 4.97E-10 T 06-07-2017 LK06_RS18640 1499bc0464b5f71129fb7027223114ca 108 Pfam PF03551 Transcriptional regulator PadR-like family 16 87 1.6E-23 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal LK06_RS18640 1499bc0464b5f71129fb7027223114ca 108 SUPERFAMILY SSF46785 4 104 1.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS18640 1499bc0464b5f71129fb7027223114ca 108 Gene3D G3DSA:1.10.10.10 5 105 6.9E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS20695 9a00e15cd2dbbc659840a2aa3053f71d 429 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 352 3.5E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 LK06_RS00795 39a4f99b0b6f9d6ebe7de12da16a3b5d 540 Pfam PF00144 Beta-lactamase 68 393 1.0E-63 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS00795 39a4f99b0b6f9d6ebe7de12da16a3b5d 540 Gene3D G3DSA:3.40.710.10 56 405 4.1E-75 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS00795 39a4f99b0b6f9d6ebe7de12da16a3b5d 540 Pfam PF11954 Domain of unknown function (DUF3471) 441 527 4.5E-14 T 06-07-2017 IPR021860 Peptidase S12, Pab87-related, C-terminal LK06_RS00795 39a4f99b0b6f9d6ebe7de12da16a3b5d 540 SUPERFAMILY SSF56601 63 406 9.58E-74 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS27100 2b9a4cd609149daf029a18ee816dd250 346 Pfam PF10935 Protein of unknown function (DUF2637) 69 217 2.7E-23 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 LK06_RS07165 c5da1fc416244a2ebd94c69819ce9340 246 SMART SM00464 5 222 2.7E-48 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 LK06_RS07165 c5da1fc416244a2ebd94c69819ce9340 246 SUPERFAMILY SSF88697 5 221 1.79E-39 T 06-07-2017 IPR015947 PUA-like domain LK06_RS07165 c5da1fc416244a2ebd94c69819ce9340 246 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 221 1.5E-28 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 LK06_RS13040 6207093ba81684350d930edb28d9bae3 102 Pfam PF14012 Protein of unknown function (DUF4229) 2 73 5.6E-21 T 06-07-2017 IPR025323 Protein of unknown function DUF4229 LK06_RS10770 8f9a3f6f6164c46c8952846e59dcf205 605 Pfam PF01380 SIS domain 462 585 3.5E-18 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 LK06_RS10770 8f9a3f6f6164c46c8952846e59dcf205 605 Pfam PF01380 SIS domain 293 417 7.8E-29 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 LK06_RS10770 8f9a3f6f6164c46c8952846e59dcf205 605 Pfam PF13522 Glutamine amidotransferase domain 64 193 1.3E-20 T 06-07-2017 LK06_RS10770 8f9a3f6f6164c46c8952846e59dcf205 605 Gene3D G3DSA:3.40.50.10490 443 605 1.7E-56 T 06-07-2017 LK06_RS10770 8f9a3f6f6164c46c8952846e59dcf205 605 SUPERFAMILY SSF53697 245 605 3.9E-98 T 06-07-2017 LK06_RS10770 8f9a3f6f6164c46c8952846e59dcf205 605 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 605 7.3E-226 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 LK06_RS10770 8f9a3f6f6164c46c8952846e59dcf205 605 Gene3D G3DSA:3.40.50.10490 245 442 1.1E-69 T 06-07-2017 LK06_RS10770 8f9a3f6f6164c46c8952846e59dcf205 605 SUPERFAMILY SSF56235 2 234 2.92E-68 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS10770 8f9a3f6f6164c46c8952846e59dcf205 605 Gene3D G3DSA:3.60.20.10 2 240 1.5E-75 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal LK06_RS10770 8f9a3f6f6164c46c8952846e59dcf205 605 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 605 37.718 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 LK06_RS10810 5f37b7ac0ad7fd648a74195cd2b7d984 439 Gene3D G3DSA:3.40.190.10 60 175 3.0E-10 T 06-07-2017 LK06_RS10810 5f37b7ac0ad7fd648a74195cd2b7d984 439 Gene3D G3DSA:3.40.190.10 176 362 3.4E-23 T 06-07-2017 LK06_RS10810 5f37b7ac0ad7fd648a74195cd2b7d984 439 SUPERFAMILY SSF53850 45 436 1.19E-46 T 06-07-2017 LK06_RS10810 5f37b7ac0ad7fd648a74195cd2b7d984 439 Pfam PF13416 Bacterial extracellular solute-binding protein 65 363 5.0E-29 T 06-07-2017 LK06_RS17595 86b90532d6bfe06ffd81e65946e3aa9d 84 Gene3D G3DSA:3.10.20.30 3 84 1.2E-13 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS17595 86b90532d6bfe06ffd81e65946e3aa9d 84 SUPERFAMILY SSF54285 4 84 1.1E-13 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp LK06_RS17595 86b90532d6bfe06ffd81e65946e3aa9d 84 Pfam PF02597 ThiS family 6 84 1.6E-9 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 LK06_RS03465 9d8d3aa60e6f4b4579c756cb73b80305 706 Gene3D G3DSA:3.30.420.10 367 476 3.9E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03465 9d8d3aa60e6f4b4579c756cb73b80305 706 Gene3D G3DSA:3.30.420.10 266 331 3.9E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03465 9d8d3aa60e6f4b4579c756cb73b80305 706 Pfam PF09299 Mu transposase, C-terminal 513 574 4.9E-7 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal LK06_RS03465 9d8d3aa60e6f4b4579c756cb73b80305 706 Pfam PF00665 Integrase core domain 268 423 5.4E-10 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 LK06_RS03465 9d8d3aa60e6f4b4579c756cb73b80305 706 SUPERFAMILY SSF53098 266 333 3.14E-11 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS03465 9d8d3aa60e6f4b4579c756cb73b80305 706 SUPERFAMILY SSF53098 368 475 3.14E-11 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS25430 6a0f39bb51c67adc44908e090777426e 342 Pfam PF11268 Protein of unknown function (DUF3071) 1 168 1.3E-54 T 06-07-2017 IPR021421 Protein of unknown function DUF3071 LK06_RS25600 bc3cc8bfb9c3c7fc757b70e5c7ef7132 227 SUPERFAMILY SSF56524 26 220 5.76E-51 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS25600 bc3cc8bfb9c3c7fc757b70e5c7ef7132 227 Pfam PF00174 Oxidoreductase molybdopterin binding domain 50 198 1.2E-27 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS25600 bc3cc8bfb9c3c7fc757b70e5c7ef7132 227 Gene3D G3DSA:3.90.420.10 30 218 6.9E-43 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LK06_RS14965 b11e3f8e4a4ec5808b0dc874e5f5de9a 532 Pfam PF13394 4Fe-4S single cluster domain 126 205 3.9E-7 T 06-07-2017 LK06_RS14965 b11e3f8e4a4ec5808b0dc874e5f5de9a 532 Pfam PF04055 Radical SAM superfamily 123 289 9.7E-19 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS14965 b11e3f8e4a4ec5808b0dc874e5f5de9a 532 Gene3D G3DSA:3.20.20.70 106 352 1.1E-49 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS14965 b11e3f8e4a4ec5808b0dc874e5f5de9a 532 SUPERFAMILY SSF102114 107 361 4.12E-38 T 06-07-2017 LK06_RS05715 f4d994aff2898c0c458b7862feddfd63 208 Gene3D G3DSA:3.90.79.10 8 183 1.3E-48 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS05715 f4d994aff2898c0c458b7862feddfd63 208 SUPERFAMILY SSF55811 9 182 1.49E-43 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS05715 f4d994aff2898c0c458b7862feddfd63 208 Pfam PF00293 NUDIX domain 48 161 3.7E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS15365 101efcd6e6027eb4076a0fa1f0bd88a3 300 Gene3D G3DSA:3.40.710.10 39 297 1.6E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS15365 101efcd6e6027eb4076a0fa1f0bd88a3 300 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 278 3.0E-43 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 LK06_RS15365 101efcd6e6027eb4076a0fa1f0bd88a3 300 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 2.1E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LK06_RS15365 101efcd6e6027eb4076a0fa1f0bd88a3 300 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 2.1E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LK06_RS15365 101efcd6e6027eb4076a0fa1f0bd88a3 300 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 157 170 2.1E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LK06_RS15365 101efcd6e6027eb4076a0fa1f0bd88a3 300 SUPERFAMILY SSF56601 42 296 1.51E-61 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS05485 d329776cf072b69cc34e6fca57aee645 116 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 70 1.7E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05485 d329776cf072b69cc34e6fca57aee645 116 SMART SM00345 11 70 2.4E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS05485 d329776cf072b69cc34e6fca57aee645 116 Gene3D G3DSA:1.10.10.10 2 71 2.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS05485 d329776cf072b69cc34e6fca57aee645 116 SUPERFAMILY SSF46785 3 80 1.39E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS11215 e3d73afa9648e2680ea1395bf5772fe2 92 Gene3D G3DSA:3.10.20.30 3 88 1.5E-29 T 06-07-2017 IPR012675 Beta-grasp domain LK06_RS11215 e3d73afa9648e2680ea1395bf5772fe2 92 Pfam PF02597 ThiS family 5 90 4.7E-19 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 LK06_RS11215 e3d73afa9648e2680ea1395bf5772fe2 92 SUPERFAMILY SSF54285 1 90 9.16E-24 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp LK06_RS11625 88785d9e96a9442c8516df853d95969c 304 Gene3D G3DSA:1.10.3720.10 32 292 1.2E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS11625 88785d9e96a9442c8516df853d95969c 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 289 3.0E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS11625 88785d9e96a9442c8516df853d95969c 304 SUPERFAMILY SSF161098 37 304 9.06E-68 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10265 b4ba4e669acdb7b26607058db4f06c4d 271 Gene3D G3DSA:3.40.630.30 114 262 3.4E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS10265 b4ba4e669acdb7b26607058db4f06c4d 271 Pfam PF13673 Acetyltransferase (GNAT) domain 181 263 2.5E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS10265 b4ba4e669acdb7b26607058db4f06c4d 271 SUPERFAMILY SSF55729 24 262 1.32E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS03535 0769d346c610a81e63b1c59dd9a16d0e 180 Pfam PF13302 Acetyltransferase (GNAT) domain 11 146 7.2E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS03535 0769d346c610a81e63b1c59dd9a16d0e 180 SUPERFAMILY SSF55729 7 172 2.3E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS03535 0769d346c610a81e63b1c59dd9a16d0e 180 Gene3D G3DSA:3.40.630.30 8 175 3.5E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS03635 d2fee5686d1bab6a9815fe7b98893db2 245 SUPERFAMILY SSF46955 36 99 1.97E-12 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS03635 d2fee5686d1bab6a9815fe7b98893db2 245 Pfam PF00376 MerR family regulatory protein 22 63 1.8E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS03635 d2fee5686d1bab6a9815fe7b98893db2 245 Gene3D G3DSA:1.10.1660.10 36 100 3.7E-17 T 06-07-2017 LK06_RS03635 d2fee5686d1bab6a9815fe7b98893db2 245 SMART SM00422 21 95 7.7E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LK06_RS20165 cb65995d3122a9d2b065d4dd190218c2 374 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 4 367 1.8E-198 T 06-07-2017 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 LK06_RS20165 cb65995d3122a9d2b065d4dd190218c2 374 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 15 297 2.1E-43 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 LK06_RS20165 cb65995d3122a9d2b065d4dd190218c2 374 Gene3D G3DSA:3.20.20.70 16 366 6.8E-76 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS20165 cb65995d3122a9d2b065d4dd190218c2 374 SUPERFAMILY SSF51412 12 77 1.04E-69 T 06-07-2017 LK06_RS20165 cb65995d3122a9d2b065d4dd190218c2 374 SUPERFAMILY SSF51412 113 369 1.04E-69 T 06-07-2017 LK06_RS20165 cb65995d3122a9d2b065d4dd190218c2 374 SMART SM01240 14 373 4.8E-28 T 06-07-2017 LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 Pfam PF02080 TrkA-C domain 150 217 4.2E-12 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 Pfam PF02254 TrkA-N domain 3 118 5.5E-25 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.2E-11 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.2E-11 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.2E-11 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.2E-11 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.2E-11 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 Gene3D G3DSA:3.40.50.720 2 143 2.0E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 Gene3D G3DSA:3.30.70.1450 148 213 1.9E-8 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 SUPERFAMILY SSF51735 2 142 9.41E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS00290 70ec64bd0704ab5f567fa58736d5e204 218 SUPERFAMILY SSF116726 145 217 3.01E-12 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 Pfam PF13229 Right handed beta helix region 158 304 3.0E-14 T 06-07-2017 LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 Gene3D G3DSA:2.160.20.10 56 357 8.3E-19 T 06-07-2017 IPR012334 Pectin lyase fold LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 SMART SM00710 132 157 7700.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 SMART SM00710 267 289 1000.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 SMART SM00710 243 265 180.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 SMART SM00710 338 359 750.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 SMART SM00710 159 181 70.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 SMART SM00710 290 327 290.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 SMART SM00710 207 242 310.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 SUPERFAMILY SSF51126 338 360 2.32E-25 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 SUPERFAMILY SSF51126 56 304 2.32E-25 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor LK06_RS25890 3b88c65062ba5866e7fcf4a171c5b843 506 SMART SM00722 158 312 0.0039 T 06-07-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain LK06_RS13170 3a1cf36ebccf01f1a9bb89b618d04334 386 SUPERFAMILY SSF53756 2 385 3.93E-18 T 06-07-2017 LK06_RS13790 9ab4440ca7db42ff060ac738c6a44ac8 162 Pfam PF11377 Protein of unknown function (DUF3180) 9 149 3.5E-37 T 06-07-2017 IPR021517 Protein of unknown function DUF3180 LK06_RS15505 32e893101fff61221fd69c97776d64d7 178 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 18 177 6.9E-52 T 06-07-2017 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit LK06_RS15505 32e893101fff61221fd69c97776d64d7 178 Pfam PF01883 Domain of unknown function DUF59 16 72 8.4E-12 T 06-07-2017 IPR002744 Domain of unknown function DUF59 LK06_RS15505 32e893101fff61221fd69c97776d64d7 178 SUPERFAMILY SSF117916 6 102 3.6E-20 T 06-07-2017 LK06_RS31130 213368a3a842c6900689c9ea4053e899 388 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 171 270 2.3E-13 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS31130 213368a3a842c6900689c9ea4053e899 388 SUPERFAMILY SSF52266 165 373 2.29E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS31130 213368a3a842c6900689c9ea4053e899 388 Gene3D G3DSA:3.40.50.1110 313 372 2.1E-9 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS31130 213368a3a842c6900689c9ea4053e899 388 Gene3D G3DSA:3.40.50.1110 168 279 2.1E-9 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS15410 81d1163aa0d17eb90c6f42c1a3dd5063 180 Pfam PF10759 Protein of unknown function (DUF2587) 30 171 1.1E-78 T 06-07-2017 IPR019695 Bacterial proteasome activator GO:0061136 LK06_RS15210 4d9345f4e6f6b6346bb239f77ea5b446 322 SUPERFAMILY SSF53590 5 321 2.09E-84 T 06-07-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain LK06_RS15210 4d9345f4e6f6b6346bb239f77ea5b446 322 Gene3D G3DSA:3.90.245.10 5 321 5.9E-95 T 06-07-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain LK06_RS15210 4d9345f4e6f6b6346bb239f77ea5b446 322 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 7 312 3.4E-67 T 06-07-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain LK06_RS10000 416f479b64331a84d422da7becc72cb8 218 SUPERFAMILY SSF52833 13 178 2.17E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS10000 416f479b64331a84d422da7becc72cb8 218 Pfam PF01323 DSBA-like thioredoxin domain 13 164 1.8E-6 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 LK06_RS10000 416f479b64331a84d422da7becc72cb8 218 Gene3D G3DSA:3.40.30.10 10 176 9.7E-10 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS31085 8bc69ef9831ae7d4344cca84b61d3457 754 Gene3D G3DSA:1.20.1640.10 536 739 1.3E-27 T 06-07-2017 LK06_RS31085 8bc69ef9831ae7d4344cca84b61d3457 754 Gene3D G3DSA:1.20.1640.10 185 368 3.2E-29 T 06-07-2017 LK06_RS31085 8bc69ef9831ae7d4344cca84b61d3457 754 SUPERFAMILY SSF82866 176 364 6.93E-28 T 06-07-2017 LK06_RS31085 8bc69ef9831ae7d4344cca84b61d3457 754 Pfam PF03176 MMPL family 438 736 1.6E-34 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS31085 8bc69ef9831ae7d4344cca84b61d3457 754 Pfam PF03176 MMPL family 71 400 5.5E-52 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 LK06_RS31085 8bc69ef9831ae7d4344cca84b61d3457 754 SUPERFAMILY SSF82866 512 733 1.23E-24 T 06-07-2017 LK06_RS16610 7c73c09549aacbbb413db3d2a35afae0 290 Pfam PF10977 Protein of unknown function (DUF2797) 34 265 6.6E-34 T 06-07-2017 IPR021246 Protein of unknown function DUF2797 LK06_RS00325 5daf29e1da7f9a9d9b08c0435f5cfc18 307 Gene3D G3DSA:3.40.50.700 22 195 5.3E-24 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS00325 5daf29e1da7f9a9d9b08c0435f5cfc18 307 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 34 180 2.8E-22 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS00325 5daf29e1da7f9a9d9b08c0435f5cfc18 307 SUPERFAMILY SSF56770 23 244 4.84E-42 T 06-07-2017 LK06_RS08695 87ef693105ea8de1f6a6f65111505ccc 80 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 74 1.9E-28 T 06-07-2017 IPR018735 Protein of unknown function DUF2277 LK06_RS22055 7c46353cee4db7004773ce157b061dd4 199 Pfam PF06210 Protein of unknown function (DUF1003) 57 158 1.6E-40 T 06-07-2017 IPR010406 Protein of unknown function DUF1003 LK06_RS13850 5a42fc1ceed85f029900bbfb99b32f5f 468 Gene3D G3DSA:3.90.1150.10 346 443 4.2E-4 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS13850 5a42fc1ceed85f029900bbfb99b32f5f 468 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 48 372 7.6E-70 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 LK06_RS13850 5a42fc1ceed85f029900bbfb99b32f5f 468 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 33 449 2.6E-188 T 06-07-2017 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 LK06_RS13850 5a42fc1ceed85f029900bbfb99b32f5f 468 SUPERFAMILY SSF53383 30 451 4.37E-127 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS13850 5a42fc1ceed85f029900bbfb99b32f5f 468 Gene3D G3DSA:3.40.640.10 82 327 1.1E-25 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS23800 3d27166ea432ca30ff1c9b7d950108c8 419 Gene3D G3DSA:3.40.50.1820 117 371 1.1E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS23800 3d27166ea432ca30ff1c9b7d950108c8 419 Pfam PF00756 Putative esterase 134 366 1.4E-15 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 LK06_RS23800 3d27166ea432ca30ff1c9b7d950108c8 419 SUPERFAMILY SSF53474 122 367 3.79E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS23705 87bd0cf0fd05e30062eb929f517dcee6 167 SUPERFAMILY SSF55874 71 158 2.13E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23705 87bd0cf0fd05e30062eb929f517dcee6 167 Pfam PF13581 Histidine kinase-like ATPase domain 47 157 2.9E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23705 87bd0cf0fd05e30062eb929f517dcee6 167 Gene3D G3DSA:3.30.565.10 77 154 9.8E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS23695 fcde6893dde149a521c2366184f8387f 384 Pfam PF03734 L,D-transpeptidase catalytic domain 230 333 5.3E-10 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 LK06_RS23695 fcde6893dde149a521c2366184f8387f 384 SUPERFAMILY SSF141523 232 357 2.09E-21 T 06-07-2017 LK06_RS23695 fcde6893dde149a521c2366184f8387f 384 Gene3D G3DSA:2.40.440.10 232 332 2.0E-15 T 06-07-2017 LK06_RS29150 8f7aa728ae210d2b88ee37f1f152fbd1 63 SUPERFAMILY SSF46894 7 62 7.82E-7 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LK06_RS29150 8f7aa728ae210d2b88ee37f1f152fbd1 63 Gene3D G3DSA:1.10.10.10 11 62 9.0E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00900 589da2133628a7adbf2b187e1290474e 138 SUPERFAMILY SSF50249 28 118 2.4E-11 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS06440 5bd4d1e13498b256516704fa77b52866 107 SUPERFAMILY SSF103481 6 105 2.35E-18 T 06-07-2017 LK06_RS06440 5bd4d1e13498b256516704fa77b52866 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.6E-27 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 LK06_RS11980 eb3c6cf2088f5d2f3bc519a013fec7c7 414 Pfam PF01548 Transposase 9 157 4.3E-25 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS11980 eb3c6cf2088f5d2f3bc519a013fec7c7 414 Pfam PF02371 Transposase IS116/IS110/IS902 family 255 340 1.1E-20 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 LK06_RS21020 eb3c6cf2088f5d2f3bc519a013fec7c7 414 Pfam PF01548 Transposase 9 157 4.3E-25 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS21020 eb3c6cf2088f5d2f3bc519a013fec7c7 414 Pfam PF02371 Transposase IS116/IS110/IS902 family 255 340 1.1E-20 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 LK06_RS22605 693ec57106a11ccb1fb74fddf619cff1 326 Pfam PF13349 Putative adhesin 138 262 9.7E-8 T 06-07-2017 IPR025164 Putative adhesin LK06_RS21210 cd19fdc8b9b56b2af07639e5b12ebaf4 334 SUPERFAMILY SSF53613 1 299 2.95E-62 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS21210 cd19fdc8b9b56b2af07639e5b12ebaf4 334 Gene3D G3DSA:3.40.1190.20 1 305 4.8E-92 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS21210 cd19fdc8b9b56b2af07639e5b12ebaf4 334 Pfam PF00294 pfkB family carbohydrate kinase 10 291 1.3E-46 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB LK06_RS21575 79a4066f402e5c3007a9959905b72d14 319 SUPERFAMILY SSF52540 30 218 1.13E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS21575 79a4066f402e5c3007a9959905b72d14 319 Pfam PF13481 AAA domain 12 177 6.6E-11 T 06-07-2017 LK06_RS21575 79a4066f402e5c3007a9959905b72d14 319 Gene3D G3DSA:3.40.50.300 18 215 1.7E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS04095 8cdbdc53e44e050bf50e9fe2fcbd9343 107 SUPERFAMILY SSF46946 56 103 1.18E-7 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 LK06_RS04095 8cdbdc53e44e050bf50e9fe2fcbd9343 107 Gene3D G3DSA:1.10.8.50 50 104 5.4E-14 T 06-07-2017 LK06_RS30080 68673fd8121a619c7ee5661233834c44 161 SUPERFAMILY SSF55961 19 152 2.33E-18 T 06-07-2017 LK06_RS30080 68673fd8121a619c7ee5661233834c44 161 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 19 152 3.8E-16 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase LK06_RS30080 68673fd8121a619c7ee5661233834c44 161 Gene3D G3DSA:3.30.530.20 18 153 1.1E-13 T 06-07-2017 IPR023393 START-like domain LK06_RS04205 39d26474553f8819a14b1d2b0fff743a 147 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 1.2E-9 T 06-07-2017 IPR009293 Uncharacterised protein family UPF0478 LK06_RS22370 4e028f24dcaff6d35d6cd3685e126bc6 271 Gene3D G3DSA:3.90.1680.10 1 261 1.8E-74 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) LK06_RS22370 4e028f24dcaff6d35d6cd3685e126bc6 271 SUPERFAMILY SSF143081 2 261 9.42E-65 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) LK06_RS22370 4e028f24dcaff6d35d6cd3685e126bc6 271 Pfam PF02586 SOS response associated peptidase (SRAP) 1 251 5.2E-67 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) LK06_RS12585 388e510b6b1b45d36caf889d431c0e12 70 Gene3D G3DSA:1.10.443.10 7 61 2.3E-7 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS12585 388e510b6b1b45d36caf889d431c0e12 70 SUPERFAMILY SSF56349 5 59 2.12E-7 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS13475 1ec7342c2c1efa80c54644f6d837f48f 271 Pfam PF15698 Phosphatase 7 269 4.3E-114 T 06-07-2017 IPR031423 Uncharacterised phosphatase SCO2771 LK06_RS00410 2c7d703aff15c851a9c865cad65fb2e3 345 SUPERFAMILY SSF52518 23 336 1.2E-94 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS00410 2c7d703aff15c851a9c865cad65fb2e3 345 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 25 333 1.5E-128 T 06-07-2017 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LK06_RS00410 2c7d703aff15c851a9c865cad65fb2e3 345 Pfam PF00676 Dehydrogenase E1 component 30 324 3.5E-82 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 LK06_RS00410 2c7d703aff15c851a9c865cad65fb2e3 345 Gene3D G3DSA:3.40.50.970 12 335 1.7E-123 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold LK06_RS12960 7a661211a49fc5d48c8c702efb47ac8b 283 SUPERFAMILY SSF54001 162 282 1.08E-37 T 06-07-2017 LK06_RS12960 7a661211a49fc5d48c8c702efb47ac8b 283 Pfam PF00877 NlpC/P60 family 181 269 2.1E-21 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS12960 7a661211a49fc5d48c8c702efb47ac8b 283 Gene3D G3DSA:3.90.1720.10 163 282 1.1E-38 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS30385 19b232fc81dfe35881da98f9c694ed09 248 Pfam PF13649 Methyltransferase domain 60 155 6.8E-20 T 06-07-2017 LK06_RS30385 19b232fc81dfe35881da98f9c694ed09 248 SUPERFAMILY SSF53335 9 219 7.44E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS30385 19b232fc81dfe35881da98f9c694ed09 248 Gene3D G3DSA:3.40.50.150 19 216 2.5E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19680 c6b0719c34a399a6b35eeeb7782006a0 385 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 176 371 3.7E-38 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS19680 c6b0719c34a399a6b35eeeb7782006a0 385 SUPERFAMILY SSF81606 158 370 7.59E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS19680 c6b0719c34a399a6b35eeeb7782006a0 385 SMART SM00331 148 371 7.6E-35 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS27975 a306fa31d2ed243f15070cf559479787 174 Pfam PF01575 MaoC like domain 12 118 2.2E-15 T 06-07-2017 IPR002539 MaoC-like domain LK06_RS27975 a306fa31d2ed243f15070cf559479787 174 Gene3D G3DSA:3.10.129.10 2 149 4.9E-42 T 06-07-2017 IPR029069 HotDog domain LK06_RS27975 a306fa31d2ed243f15070cf559479787 174 SUPERFAMILY SSF54637 2 149 1.86E-42 T 06-07-2017 IPR029069 HotDog domain LK06_RS07000 1256b0d8bc5585e491058161d2f8a880 357 Gene3D G3DSA:3.20.20.70 1 331 2.9E-68 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS07000 1256b0d8bc5585e491058161d2f8a880 357 Pfam PF03060 Nitronate monooxygenase 3 335 8.8E-93 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 LK06_RS07000 1256b0d8bc5585e491058161d2f8a880 357 SUPERFAMILY SSF51412 299 343 4.73E-60 T 06-07-2017 LK06_RS07000 1256b0d8bc5585e491058161d2f8a880 357 SUPERFAMILY SSF51412 1 257 4.73E-60 T 06-07-2017 LK06_RS28585 1f0f187f2105d7235061cca25eeffca6 138 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 2.0E-31 T 06-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 LK06_RS27090 ff6ee982bdae877aff70de723afe4c09 484 Pfam PF13672 Protein phosphatase 2C 212 462 3.4E-27 T 06-07-2017 LK06_RS30400 ce1c784055c733c39cb2ac111bfca62b 109 Gene3D G3DSA:3.40.50.1820 3 99 1.3E-15 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30400 ce1c784055c733c39cb2ac111bfca62b 109 SUPERFAMILY SSF53474 16 92 2.39E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS30400 ce1c784055c733c39cb2ac111bfca62b 109 Pfam PF05448 Acetyl xylan esterase (AXE1) 2 108 9.3E-30 T 06-07-2017 IPR008391 Acetyl xylan esterase LK06_RS01600 1632580b891b3ed5f3555d6242b9ede1 294 Pfam PF03466 LysR substrate binding domain 88 293 8.3E-47 T 06-07-2017 IPR005119 LysR, substrate-binding LK06_RS01600 1632580b891b3ed5f3555d6242b9ede1 294 Gene3D G3DSA:1.10.10.10 1 84 9.1E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01600 1632580b891b3ed5f3555d6242b9ede1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.7E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS01600 1632580b891b3ed5f3555d6242b9ede1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.7E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS01600 1632580b891b3ed5f3555d6242b9ede1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.7E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS01600 1632580b891b3ed5f3555d6242b9ede1 294 Gene3D G3DSA:3.40.190.10 178 269 1.1E-23 T 06-07-2017 LK06_RS01600 1632580b891b3ed5f3555d6242b9ede1 294 SUPERFAMILY SSF46785 1 110 5.87E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01600 1632580b891b3ed5f3555d6242b9ede1 294 SUPERFAMILY SSF53850 90 294 3.19E-43 T 06-07-2017 LK06_RS01600 1632580b891b3ed5f3555d6242b9ede1 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.1E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LK06_RS01600 1632580b891b3ed5f3555d6242b9ede1 294 Gene3D G3DSA:3.40.190.10 90 177 7.1E-20 T 06-07-2017 LK06_RS23505 97e977c118a125da0f4647d00a3ee571 566 SUPERFAMILY SSF51703 6 560 1.07E-190 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS23505 97e977c118a125da0f4647d00a3ee571 566 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 564 5.8E-199 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS23505 97e977c118a125da0f4647d00a3ee571 566 Gene3D G3DSA:3.20.20.240 28 560 9.1E-214 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS23505 97e977c118a125da0f4647d00a3ee571 566 Pfam PF01642 Methylmalonyl-CoA mutase 29 558 1.3E-211 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS10225 0f37f083b27061f6620ef61b233bfb76 535 Pfam PF00350 Dynamin family 65 193 2.6E-8 T 06-07-2017 IPR022812 Dynamin superfamily LK06_RS10225 0f37f083b27061f6620ef61b233bfb76 535 SUPERFAMILY SSF52540 41 250 3.47E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10225 0f37f083b27061f6620ef61b233bfb76 535 Gene3D G3DSA:3.40.50.300 155 232 9.1E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10225 0f37f083b27061f6620ef61b233bfb76 535 Gene3D G3DSA:3.40.50.300 61 107 9.1E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22330 89a17a6238366c06adf8bc6f48f7f054 138 Pfam PF01475 Ferric uptake regulator family 11 102 5.0E-25 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 LK06_RS22330 89a17a6238366c06adf8bc6f48f7f054 138 Gene3D G3DSA:1.10.10.10 2 82 6.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS22330 89a17a6238366c06adf8bc6f48f7f054 138 SUPERFAMILY SSF46785 3 133 1.7E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS13745 ad1049261c1ceba170e8082116a01c50 167 Pfam PF03703 Bacterial PH domain 78 156 1.1E-16 T 06-07-2017 IPR005182 Domain of unknown function DUF304 LK06_RS07725 a1c8262da47ebeb1eb05d14519f2010f 246 Pfam PF11241 Protein of unknown function (DUF3043) 78 244 3.5E-63 T 06-07-2017 IPR021403 Protein of unknown function DUF3043 LK06_RS10710 d2fc9af8705eacbc9b5863a67b507933 201 Gene3D G3DSA:1.10.357.10 57 171 3.1E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS10710 d2fc9af8705eacbc9b5863a67b507933 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS10710 d2fc9af8705eacbc9b5863a67b507933 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS10710 d2fc9af8705eacbc9b5863a67b507933 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 5.3E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS10710 d2fc9af8705eacbc9b5863a67b507933 201 SUPERFAMILY SSF46689 3 70 3.19E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS10710 d2fc9af8705eacbc9b5863a67b507933 201 Gene3D G3DSA:1.10.10.60 4 56 4.0E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS18940 be274c849e18322730e3ee8ab4e536ab 262 Gene3D G3DSA:3.90.226.10 10 231 7.0E-49 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS18940 be274c849e18322730e3ee8ab4e536ab 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 232 4.4E-33 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS18940 be274c849e18322730e3ee8ab4e536ab 262 SUPERFAMILY SSF52096 6 238 5.89E-49 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS29200 40fe2bfadfead114478d8461abcff203 189 Pfam PF01590 GAF domain 46 173 2.7E-5 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS29200 40fe2bfadfead114478d8461abcff203 189 Gene3D G3DSA:3.30.450.40 33 174 3.3E-5 T 06-07-2017 IPR029016 GAF domain-like LK06_RS11040 b6b3d13e49d7829ad48007b32ad880bd 172 PIRSF PIRSF008757 10 172 4.5E-63 T 06-07-2017 IPR010371 Uncharacterised protein family UPF0303 LK06_RS11040 b6b3d13e49d7829ad48007b32ad880bd 172 SUPERFAMILY SSF143744 24 163 6.41E-29 T 06-07-2017 LK06_RS11040 b6b3d13e49d7829ad48007b32ad880bd 172 Pfam PF03928 Haem-degrading 33 161 1.7E-34 T 06-07-2017 IPR005624 Haem-degrading LK06_RS11040 b6b3d13e49d7829ad48007b32ad880bd 172 Hamap MF_00761 UPF0303 protein . 11 166 33.613 T 06-07-2017 IPR010371 Uncharacterised protein family UPF0303 LK06_RS00550 380812f6cd5462cea89cd2ec6073d9f3 287 SUPERFAMILY SSF103481 37 119 2.48E-7 T 06-07-2017 LK06_RS29650 ce217243adf2ec97070fed07ec376108 142 Gene3D G3DSA:2.30.110.10 3 138 8.6E-41 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS29650 ce217243adf2ec97070fed07ec376108 142 SUPERFAMILY SSF50475 3 137 1.8E-33 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS29650 ce217243adf2ec97070fed07ec376108 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 91 1.4E-19 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LK06_RS29650 ce217243adf2ec97070fed07ec376108 142 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 135 2.0E-41 T 06-07-2017 IPR019920 F420-binding domain, putative LK06_RS03960 a9075301efabd50dc15ab253c605f9a7 255 Pfam PF13460 NAD(P)H-binding 8 169 1.5E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03960 a9075301efabd50dc15ab253c605f9a7 255 Gene3D G3DSA:3.40.50.720 4 204 4.2E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS03960 a9075301efabd50dc15ab253c605f9a7 255 SUPERFAMILY SSF51735 4 212 7.05E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS10950 007833de229662c68f39a17591ce4a58 247 SUPERFAMILY SSF161098 14 201 7.72E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10950 007833de229662c68f39a17591ce4a58 247 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 2.5E-21 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 LK06_RS10950 007833de229662c68f39a17591ce4a58 247 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 12 216 1.9E-64 T 06-07-2017 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC LK06_RS10950 007833de229662c68f39a17591ce4a58 247 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 214 8.8E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10950 007833de229662c68f39a17591ce4a58 247 Gene3D G3DSA:1.10.3720.10 13 216 2.1E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 255 1.3E-52 T 06-07-2017 LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 Gene3D G3DSA:3.40.50.720 4 256 4.2E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 194 0.0013 T 06-07-2017 LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 SUPERFAMILY SSF51735 8 256 3.61E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 4.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 4.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS31480 b6130364cac4dea5e35723793a8f3e29 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 4.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS15490 10d9701df14785e6a8e455b2a86d7d8e 338 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 30 318 2.1E-160 T 06-07-2017 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 LK06_RS15490 10d9701df14785e6a8e455b2a86d7d8e 338 SUPERFAMILY SSF47240 50 293 1.1E-86 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS15490 10d9701df14785e6a8e455b2a86d7d8e 338 Pfam PF05138 Phenylacetic acid catabolic protein 40 314 3.2E-107 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 LK06_RS15490 10d9701df14785e6a8e455b2a86d7d8e 338 Gene3D G3DSA:1.20.1260.10 40 295 4.2E-108 T 06-07-2017 IPR012347 Ferritin-related LK06_RS04780 9755aa15755d15f640bdf8e57c437faf 446 SUPERFAMILY SSF48452 215 365 1.71E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS04780 9755aa15755d15f640bdf8e57c437faf 446 Gene3D G3DSA:1.25.40.10 214 406 1.6E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18765 3531c571a2564923f535227373e331c5 415 SUPERFAMILY SSF109854 106 287 1.81E-14 T 06-07-2017 LK06_RS18765 3531c571a2564923f535227373e331c5 415 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 118 281 4.3E-6 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 LK06_RS18765 3531c571a2564923f535227373e331c5 415 Pfam PF13490 Putative zinc-finger 38 67 1.3E-5 T 06-07-2017 IPR027383 Putative zinc-finger LK06_RS30075 1fd4611e49ab7c71fb6d0a76377b2d41 374 Gene3D G3DSA:3.40.50.1100 66 162 5.6E-22 T 06-07-2017 LK06_RS30075 1fd4611e49ab7c71fb6d0a76377b2d41 374 SUPERFAMILY SSF53686 42 354 2.75E-69 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS30075 1fd4611e49ab7c71fb6d0a76377b2d41 374 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 48 334 1.1E-44 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS30075 1fd4611e49ab7c71fb6d0a76377b2d41 374 Gene3D G3DSA:3.40.50.1100 163 353 1.1E-33 T 06-07-2017 LK06_RS25710 9a28cb8730bbc2f2c0cfcc06d2f40482 122 Gene3D G3DSA:1.20.120.520 5 62 8.3E-5 T 06-07-2017 LK06_RS18740 f16862f5809f571c4cbde4b4047f1999 461 SUPERFAMILY SSF48452 351 420 3.41E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18740 f16862f5809f571c4cbde4b4047f1999 461 SUPERFAMILY SSF48452 225 255 3.41E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS18740 f16862f5809f571c4cbde4b4047f1999 461 Gene3D G3DSA:1.25.40.10 216 437 2.9E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05545 0cd8c588a1eb03c01f20c29cd2c69c78 323 Gene3D G3DSA:1.10.1780.10 174 226 1.2E-6 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS05545 0cd8c588a1eb03c01f20c29cd2c69c78 323 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.8E-15 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS05545 0cd8c588a1eb03c01f20c29cd2c69c78 323 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 178 214 1.8E-6 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS05545 0cd8c588a1eb03c01f20c29cd2c69c78 323 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 92 139 1.3E-11 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS05545 0cd8c588a1eb03c01f20c29cd2c69c78 323 SUPERFAMILY SSF81923 4 141 7.26E-27 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS05545 0cd8c588a1eb03c01f20c29cd2c69c78 323 Gene3D G3DSA:1.10.1780.10 1 140 4.5E-44 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS05545 0cd8c588a1eb03c01f20c29cd2c69c78 323 SUPERFAMILY SSF81923 173 220 2.16E-5 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 LK06_RS12905 d43672cc21ea81570458692316f7ef39 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.628 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 LK06_RS12905 d43672cc21ea81570458692316f7ef39 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 9.9E-24 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 LK06_RS05915 091669d463ef1136271b172f80d0942b 78 Pfam PF03777 Small secreted domain (DUF320) 25 77 1.1E-21 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS09040 6d6300bc528112c903c0b1402ac15025 137 Pfam PF01850 PIN domain 6 123 1.7E-11 T 06-07-2017 IPR002716 PIN domain LK06_RS09040 6d6300bc528112c903c0b1402ac15025 137 SUPERFAMILY SSF88723 6 122 7.29E-13 T 06-07-2017 IPR029060 PIN domain-like LK06_RS09040 6d6300bc528112c903c0b1402ac15025 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 129 11.206 T 06-07-2017 IPR022907 VapC family GO:0004540 LK06_RS09040 6d6300bc528112c903c0b1402ac15025 137 Gene3D G3DSA:3.40.50.1010 5 123 2.7E-6 T 06-07-2017 IPR029060 PIN domain-like LK06_RS04810 dae6f6782f8699aa1e2c66935405b26d 127 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS04810 dae6f6782f8699aa1e2c66935405b26d 127 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.7E-38 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS04810 dae6f6782f8699aa1e2c66935405b26d 127 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.7E-38 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS04810 dae6f6782f8699aa1e2c66935405b26d 127 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.7E-38 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS04810 dae6f6782f8699aa1e2c66935405b26d 127 SUPERFAMILY SSF74731 3 117 2.09E-45 T 06-07-2017 LK06_RS04810 dae6f6782f8699aa1e2c66935405b26d 127 Pfam PF00453 Ribosomal protein L20 3 109 2.0E-44 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS04810 dae6f6782f8699aa1e2c66935405b26d 127 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 2.0E-23 T 06-07-2017 LK06_RS04810 dae6f6782f8699aa1e2c66935405b26d 127 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 113 1.6E-44 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS04810 dae6f6782f8699aa1e2c66935405b26d 127 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.925 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LK06_RS04810 dae6f6782f8699aa1e2c66935405b26d 127 Gene3D G3DSA:1.10.1900.20 56 117 6.6E-32 T 06-07-2017 LK06_RS16925 d28214a49a59ab5a4875ce44c9443b66 101 Gene3D G3DSA:3.40.1350.10 2 66 9.3E-7 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 LK06_RS06370 bc4862b32e84d161c7bf6d89a1fde1a2 156 Pfam PF13302 Acetyltransferase (GNAT) domain 4 131 1.9E-18 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS06370 bc4862b32e84d161c7bf6d89a1fde1a2 156 Gene3D G3DSA:3.40.630.30 3 145 1.3E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS06370 bc4862b32e84d161c7bf6d89a1fde1a2 156 SUPERFAMILY SSF55729 3 150 1.24E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS16540 16bc77af4257fa663057267d149129cb 325 SUPERFAMILY SSF75011 189 312 1.31E-8 T 06-07-2017 LK06_RS16540 16bc77af4257fa663057267d149129cb 325 SUPERFAMILY SSF75011 47 106 1.31E-8 T 06-07-2017 LK06_RS12475 368794e7fd8a4d616b4469760d48276f 408 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 LK06_RS12475 368794e7fd8a4d616b4469760d48276f 408 Gene3D G3DSA:3.40.640.10 53 282 4.0E-75 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS12475 368794e7fd8a4d616b4469760d48276f 408 Gene3D G3DSA:3.90.1150.10 283 405 9.7E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS12475 368794e7fd8a4d616b4469760d48276f 408 SUPERFAMILY SSF53383 12 405 1.9E-112 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS12475 368794e7fd8a4d616b4469760d48276f 408 Pfam PF00155 Aminotransferase class I and II 40 394 4.2E-73 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS03925 6942f26224bc472c81d60a4d5393efcf 151 Pfam PF10756 Bacterial PH domain 65 135 1.5E-15 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 LK06_RS29645 008345108ea4aca1b0b38afe6bd8f4f4 200 Pfam PF03029 Conserved hypothetical ATP binding protein 21 187 9.0E-25 T 06-07-2017 IPR004130 GPN-loop GTPase LK06_RS29645 008345108ea4aca1b0b38afe6bd8f4f4 200 Gene3D G3DSA:3.40.50.300 15 186 1.2E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS29645 008345108ea4aca1b0b38afe6bd8f4f4 200 SUPERFAMILY SSF52540 17 187 4.2E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30320 0dddb2c5b337d97cb449968d617bad5d 153 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 28 145 19.007 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LK06_RS30320 0dddb2c5b337d97cb449968d617bad5d 153 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 29 139 2.7E-21 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LK06_RS30320 0dddb2c5b337d97cb449968d617bad5d 153 TIGRFAM TIGR00494 crcB: protein CrcB 30 141 1.8E-24 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LK06_RS03455 71040c8610d90fb0d89df24c1fa9eb6b 445 Pfam PF13546 DDE superfamily endonuclease 31 242 8.5E-42 T 06-07-2017 LK06_RS03455 71040c8610d90fb0d89df24c1fa9eb6b 445 SUPERFAMILY SSF53098 71 379 1.21E-17 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS08680 ec194e3f3764e8fd7615176315e5b78a 214 Pfam PF09335 SNARE associated Golgi protein 43 178 2.7E-9 T 06-07-2017 IPR032816 SNARE associated Golgi protein LK06_RS01985 f8746a6bc9e5378a94cd26bc2caa7def 434 Pfam PF13556 PucR C-terminal helix-turn-helix domain 370 427 2.6E-16 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS30865 09f8d32cb4f3932e36bb01d4ed63d91b 225 Gene3D G3DSA:3.60.160.10 32 220 7.1E-40 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS30865 09f8d32cb4f3932e36bb01d4ed63d91b 225 SUPERFAMILY SSF51219 32 218 9.68E-44 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain LK06_RS30865 09f8d32cb4f3932e36bb01d4ed63d91b 225 Pfam PF01987 Mitochondrial biogenesis AIM24 33 214 2.8E-31 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS23560 df86c2b4bef077349d35d757bb5c97af 542 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 86 105 2.0E-7 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS23560 df86c2b4bef077349d35d757bb5c97af 542 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 479 492 2.0E-7 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS23560 df86c2b4bef077349d35d757bb5c97af 542 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 391 405 2.0E-7 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS23560 df86c2b4bef077349d35d757bb5c97af 542 Gene3D G3DSA:3.40.710.10 273 508 2.2E-38 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS23560 df86c2b4bef077349d35d757bb5c97af 542 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 50 508 4.9E-55 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS23560 df86c2b4bef077349d35d757bb5c97af 542 Gene3D G3DSA:3.40.710.10 62 102 2.0E-6 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS23560 df86c2b4bef077349d35d757bb5c97af 542 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 74 475 3.2E-42 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LK06_RS23560 df86c2b4bef077349d35d757bb5c97af 542 SUPERFAMILY SSF56601 177 521 1.25E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS23560 df86c2b4bef077349d35d757bb5c97af 542 SUPERFAMILY SSF56601 45 143 1.25E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS19860 68a06d59224a180f6a0de908ec86dd07 172 Pfam PF14431 YwqJ-like deaminase 38 162 1.0E-22 T 06-07-2017 IPR025968 YwqJ-like deaminase LK06_RS30885 e23ef13a5a4bf980bab0cc0c1d46b875 288 SUPERFAMILY SSF52402 148 287 3.35E-25 T 06-07-2017 LK06_RS30885 e23ef13a5a4bf980bab0cc0c1d46b875 288 Gene3D G3DSA:3.40.50.620 1 134 9.3E-30 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS30885 e23ef13a5a4bf980bab0cc0c1d46b875 288 Gene3D G3DSA:3.40.50.620 143 286 1.0E-25 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS30885 e23ef13a5a4bf980bab0cc0c1d46b875 288 SUPERFAMILY SSF52402 3 137 3.18E-25 T 06-07-2017 LK06_RS30885 e23ef13a5a4bf980bab0cc0c1d46b875 288 PRINTS PR01438 Universal stress protein signature 2 20 8.8E-12 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS30885 e23ef13a5a4bf980bab0cc0c1d46b875 288 PRINTS PR01438 Universal stress protein signature 112 134 8.8E-12 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS30885 e23ef13a5a4bf980bab0cc0c1d46b875 288 PRINTS PR01438 Universal stress protein signature 94 106 8.8E-12 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS30885 e23ef13a5a4bf980bab0cc0c1d46b875 288 Pfam PF00582 Universal stress protein family 1 134 6.0E-20 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS30885 e23ef13a5a4bf980bab0cc0c1d46b875 288 Pfam PF00582 Universal stress protein family 156 286 5.0E-19 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS12670 adb0d597761fa17bae288a8689e8bf64 582 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 80 136 3.0E-20 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12670 adb0d597761fa17bae288a8689e8bf64 582 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 31 148 8.4E-32 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS12670 adb0d597761fa17bae288a8689e8bf64 582 SUPERFAMILY SSF143243 20 154 1.1E-36 T 06-07-2017 LK06_RS00645 f555d47da09749ba7628fbd1844457b1 373 SUPERFAMILY SSF55729 150 318 2.01E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS00645 f555d47da09749ba7628fbd1844457b1 373 Pfam PF13480 Acetyltransferase (GNAT) domain 156 296 5.0E-37 T 06-07-2017 LK06_RS08955 e97c4e19b279391cb76ac7f642054b00 467 SUPERFAMILY SSF52096 4 226 2.42E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS08955 e97c4e19b279391cb76ac7f642054b00 467 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 111 129 3.3E-15 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 LK06_RS08955 e97c4e19b279391cb76ac7f642054b00 467 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 77 91 3.3E-15 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 LK06_RS08955 e97c4e19b279391cb76ac7f642054b00 467 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 148 165 3.3E-15 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 LK06_RS08955 e97c4e19b279391cb76ac7f642054b00 467 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 177 188 3.3E-15 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 LK06_RS08955 e97c4e19b279391cb76ac7f642054b00 467 SUPERFAMILY SSF52096 253 456 1.57E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS08955 e97c4e19b279391cb76ac7f642054b00 467 Gene3D G3DSA:3.90.226.10 4 224 1.7E-37 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS08955 e97c4e19b279391cb76ac7f642054b00 467 Pfam PF01039 Carboxyl transferase domain 299 435 2.8E-11 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS08955 e97c4e19b279391cb76ac7f642054b00 467 Pfam PF01039 Carboxyl transferase domain 52 200 1.0E-12 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LK06_RS08955 e97c4e19b279391cb76ac7f642054b00 467 Gene3D G3DSA:3.90.226.10 255 457 1.8E-31 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS26180 23dd3a97a600ea2bad410aadb89a223f 213 Pfam PF01596 O-methyltransferase 49 212 4.5E-47 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 LK06_RS26180 23dd3a97a600ea2bad410aadb89a223f 213 Gene3D G3DSA:3.40.50.150 11 212 3.8E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26180 23dd3a97a600ea2bad410aadb89a223f 213 SUPERFAMILY SSF53335 35 212 8.36E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS24505 5c36ea80305d4bbdf77d23a97ed02653 252 SUPERFAMILY SSF53633 16 245 7.85E-68 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS24505 5c36ea80305d4bbdf77d23a97ed02653 252 Gene3D G3DSA:3.40.1160.10 9 245 9.7E-82 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS24505 5c36ea80305d4bbdf77d23a97ed02653 252 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 16 245 8.9E-91 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 LK06_RS24505 5c36ea80305d4bbdf77d23a97ed02653 252 PIRSF PIRSF005650 12 251 3.3E-88 T 06-07-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 LK06_RS24505 5c36ea80305d4bbdf77d23a97ed02653 252 Hamap MF_01220_B Uridylate kinase [pyrH]. 12 246 42.699 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 LK06_RS24505 5c36ea80305d4bbdf77d23a97ed02653 252 Pfam PF00696 Amino acid kinase family 16 224 3.2E-25 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase LK06_RS18955 fbe52826275970b7e25344a671f37598 532 Gene3D G3DSA:2.30.38.10 359 433 2.1E-24 T 06-07-2017 LK06_RS18955 fbe52826275970b7e25344a671f37598 532 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 523 8.8E-21 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain LK06_RS18955 fbe52826275970b7e25344a671f37598 532 SUPERFAMILY SSF56801 5 531 2.35E-142 T 06-07-2017 LK06_RS18955 fbe52826275970b7e25344a671f37598 532 Gene3D G3DSA:3.40.50.980 7 198 1.1E-34 T 06-07-2017 LK06_RS18955 fbe52826275970b7e25344a671f37598 532 Gene3D G3DSA:3.30.300.30 434 530 6.6E-29 T 06-07-2017 LK06_RS18955 fbe52826275970b7e25344a671f37598 532 Gene3D G3DSA:3.40.50.980 199 349 6.3E-39 T 06-07-2017 LK06_RS18955 fbe52826275970b7e25344a671f37598 532 ProSitePatterns PS00455 Putative AMP-binding domain signature. 190 201 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS18955 fbe52826275970b7e25344a671f37598 532 Pfam PF00501 AMP-binding enzyme 15 439 4.7E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS27040 83e5314e4f29edf56dea44480e446729 252 SUPERFAMILY SSF53474 17 244 8.45E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS27040 83e5314e4f29edf56dea44480e446729 252 Gene3D G3DSA:3.40.50.1820 17 244 8.2E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS08405 96af16dbab03e65b781df1755781a74f 500 SMART SM00955 52 393 6.0E-19 T 06-07-2017 LK06_RS08405 96af16dbab03e65b781df1755781a74f 500 SUPERFAMILY SSF50249 20 437 3.2E-63 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS08405 96af16dbab03e65b781df1755781a74f 500 Pfam PF00773 RNB domain 91 384 5.1E-25 T 06-07-2017 LK06_RS05645 0e5a5c5424713b469621087d8a05253d 231 TIGRFAM TIGR00017 cmk: cytidylate kinase 12 222 3.0E-63 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 LK06_RS05645 0e5a5c5424713b469621087d8a05253d 231 Pfam PF02224 Cytidylate kinase 14 225 1.1E-65 T 06-07-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 LK06_RS05645 0e5a5c5424713b469621087d8a05253d 231 SUPERFAMILY SSF52540 10 227 1.93E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05645 0e5a5c5424713b469621087d8a05253d 231 Gene3D G3DSA:3.40.50.300 10 225 7.4E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS05645 0e5a5c5424713b469621087d8a05253d 231 Hamap MF_00238 Cytidylate kinase [cmk]. 12 228 30.794 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 LK06_RS08155 271306c5a3f9a1010388db7ee6354cb5 238 Pfam PF11303 Protein of unknown function (DUF3105) 108 230 2.1E-43 T 06-07-2017 IPR021454 Protein of unknown function DUF3105 LK06_RS19330 507b4476c4ab4de5166a07fe5537fba1 161 SUPERFAMILY SSF81330 18 129 1.83E-23 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 LK06_RS19330 507b4476c4ab4de5166a07fe5537fba1 161 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 10 150 3.9E-33 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 LK06_RS19330 507b4476c4ab4de5166a07fe5537fba1 161 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 19 32 - T 06-07-2017 IPR019823 Large-conductance mechanosensitive channel, conserved site LK06_RS19330 507b4476c4ab4de5166a07fe5537fba1 161 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 9 151 7.9E-22 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 LK06_RS22355 d43fd599f2cf7f371c9ee827192b7ba0 336 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 334 26.683 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 LK06_RS22355 d43fd599f2cf7f371c9ee827192b7ba0 336 Gene3D G3DSA:3.40.50.300 113 271 9.2E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22355 d43fd599f2cf7f371c9ee827192b7ba0 336 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 322 6.9E-42 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 LK06_RS22355 d43fd599f2cf7f371c9ee827192b7ba0 336 Pfam PF03193 Protein of unknown function, DUF258 95 271 1.2E-41 T 06-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 LK06_RS22355 d43fd599f2cf7f371c9ee827192b7ba0 336 Gene3D G3DSA:1.10.40.50 273 333 2.3E-13 T 06-07-2017 LK06_RS22355 d43fd599f2cf7f371c9ee827192b7ba0 336 SUPERFAMILY SSF52540 113 332 1.64E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22740 17d738cf2af2998b44d3b4647e245338 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 69 4.4E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS22740 17d738cf2af2998b44d3b4647e245338 217 SUPERFAMILY SSF46689 10 83 8.72E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS22740 17d738cf2af2998b44d3b4647e245338 217 Gene3D G3DSA:1.10.357.10 9 203 1.7E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS26275 fd0123b10c6c3a2a213b34b193c48a3d 114 Gene3D G3DSA:3.10.180.10 8 111 5.6E-8 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS26275 fd0123b10c6c3a2a213b34b193c48a3d 114 SUPERFAMILY SSF54593 3 111 3.6E-8 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS24795 c13c138c695829d5a9d80022f80f0497 1058 Pfam PF13614 AAA domain 686 831 3.8E-10 T 06-07-2017 IPR025669 AAA domain LK06_RS24795 c13c138c695829d5a9d80022f80f0497 1058 Gene3D G3DSA:3.40.50.300 685 922 5.9E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24795 c13c138c695829d5a9d80022f80f0497 1058 SUPERFAMILY SSF52540 684 924 6.08E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS27575 3619a4e1aaa3d593e5089bb1c900d17a 334 SUPERFAMILY SSF53822 51 323 1.16E-48 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS27575 3619a4e1aaa3d593e5089bb1c900d17a 334 Pfam PF13407 Periplasmic binding protein domain 53 297 1.2E-39 T 06-07-2017 IPR025997 Periplasmic binding protein LK06_RS27575 3619a4e1aaa3d593e5089bb1c900d17a 334 Gene3D G3DSA:3.40.50.2300 170 312 1.0E-14 T 06-07-2017 LK06_RS27575 3619a4e1aaa3d593e5089bb1c900d17a 334 Gene3D G3DSA:3.40.50.2300 47 169 5.6E-30 T 06-07-2017 LK06_RS06950 ca755b76a569f39a4334dbbb74f81065 69 Gene3D G3DSA:3.40.630.30 2 49 7.6E-5 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS25750 106d586076be91d268a92b944bab7ce1 255 Gene3D G3DSA:3.50.50.60 139 226 2.9E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS25750 106d586076be91d268a92b944bab7ce1 255 SUPERFAMILY SSF51905 140 244 1.3E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS07585 229143b638a1e9a9526516c3ecd1f9b0 447 Pfam PF05991 YacP-like NYN domain 328 445 3.1E-17 T 06-07-2017 IPR010298 Protein of unknown function DUF901 LK06_RS16155 bba6f77f75307fab2730045762f30360 133 SUPERFAMILY SSF88723 8 125 2.16E-6 T 06-07-2017 IPR029060 PIN domain-like LK06_RS06140 8f4e52326a54be08c8bd67495436c757 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 1.5E-44 T 06-07-2017 LK06_RS06140 8f4e52326a54be08c8bd67495436c757 251 SUPERFAMILY SSF51735 1 248 1.03E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06140 8f4e52326a54be08c8bd67495436c757 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.0E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06140 8f4e52326a54be08c8bd67495436c757 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.0E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06140 8f4e52326a54be08c8bd67495436c757 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.0E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06140 8f4e52326a54be08c8bd67495436c757 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.0E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS06140 8f4e52326a54be08c8bd67495436c757 251 Gene3D G3DSA:3.40.50.720 1 247 3.8E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS06140 8f4e52326a54be08c8bd67495436c757 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 174 0.0044 T 06-07-2017 LK06_RS22120 e069129941a78002fbfbf64398f95080 251 SUPERFAMILY SSF47240 41 162 9.18E-10 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS22120 e069129941a78002fbfbf64398f95080 251 Gene3D G3DSA:1.20.1260.10 38 163 5.0E-9 T 06-07-2017 IPR012347 Ferritin-related LK06_RS22120 e069129941a78002fbfbf64398f95080 251 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 35 219 1.1E-97 T 06-07-2017 LK06_RS11285 02273eebfcc6828ba5d8acdf23a9f7b2 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 24 121 2.1E-34 T 06-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 LK06_RS31105 d6e004b693f4fd609891c85df1fc42a2 63 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 1 63 4.9E-12 T 06-07-2017 IPR026496 Putative ATP-grasp target RiPP LK06_RS31105 d6e004b693f4fd609891c85df1fc42a2 63 Pfam PF14404 Ribosomally synthesized peptide in Streptomyces species 1 63 5.0E-36 T 06-07-2017 IPR025744 Ribosomally synthesised peptide in Streptomyces LK06_RS11760 23ddae2c079549ea8e722b84dbe8260a 594 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 331 593 2.3E-49 T 06-07-2017 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal LK06_RS11760 23ddae2c079549ea8e722b84dbe8260a 594 SUPERFAMILY SSF50969 320 574 1.57E-11 T 06-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like LK06_RS11760 23ddae2c079549ea8e722b84dbe8260a 594 Gene3D G3DSA:2.120.10.30 352 583 5.5E-11 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like LK06_RS11760 23ddae2c079549ea8e722b84dbe8260a 594 Hamap MF_01373 Lipoprotein LpqB [lpqB]. 1 594 21.448 T 06-07-2017 IPR023959 Lipoprotein LpqB LK06_RS11760 23ddae2c079549ea8e722b84dbe8260a 594 SMART SM00909 208 303 9.0E-6 T 06-07-2017 IPR019606 GerMN domain LK06_RS11760 23ddae2c079549ea8e722b84dbe8260a 594 Pfam PF10646 Sporulation and spore germination 179 292 5.8E-7 T 06-07-2017 IPR019606 GerMN domain LK06_RS18850 38cc7b4f9f3e71ef0bc87f49d94eef09 262 Gene3D G3DSA:1.10.12.10 204 262 3.8E-20 T 06-07-2017 IPR014748 Crontonase, C-terminal LK06_RS18850 38cc7b4f9f3e71ef0bc87f49d94eef09 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 261 1.4E-63 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS18850 38cc7b4f9f3e71ef0bc87f49d94eef09 262 Gene3D G3DSA:3.90.226.10 7 202 8.3E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS18850 38cc7b4f9f3e71ef0bc87f49d94eef09 262 SUPERFAMILY SSF52096 7 262 1.41E-84 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS19665 a8ec5ca8704c52c44970c4e1e1a844dd 350 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 249 334 1.0E-21 T 06-07-2017 LK06_RS19665 a8ec5ca8704c52c44970c4e1e1a844dd 350 Pfam PF13190 PDGLE domain 253 329 3.4E-13 T 06-07-2017 IPR025937 PDGLE domain LK06_RS19665 a8ec5ca8704c52c44970c4e1e1a844dd 350 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 208 1.6E-59 T 06-07-2017 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 LK06_RS17670 f3fec2cc2304fd108f5da64ac627a425 145 SUPERFAMILY SSF46785 6 135 5.35E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17670 f3fec2cc2304fd108f5da64ac627a425 145 Gene3D G3DSA:1.10.10.10 5 82 4.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS17670 f3fec2cc2304fd108f5da64ac627a425 145 Pfam PF01475 Ferric uptake regulator family 13 122 7.2E-24 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 LK06_RS06205 b6c6acc15e9dc539cdc513fae9af960f 375 SUPERFAMILY SSF53474 144 374 7.28E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS06205 b6c6acc15e9dc539cdc513fae9af960f 375 Pfam PF12697 Alpha/beta hydrolase family 158 359 8.7E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS06205 b6c6acc15e9dc539cdc513fae9af960f 375 Gene3D G3DSA:3.40.50.1820 138 371 3.5E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS01415 0ce88a12c364c5e687f0545554153e7a 472 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 37 374 1.0E-25 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 LK06_RS01415 0ce88a12c364c5e687f0545554153e7a 472 Gene3D G3DSA:3.40.640.10 73 327 6.7E-57 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS01415 0ce88a12c364c5e687f0545554153e7a 472 SUPERFAMILY SSF53383 35 397 3.51E-62 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS30055 ab6e98614ec598a3c768931ee53f0f37 192 Pfam PF16157 Domain of unknown function (DUF4865) 1 179 6.8E-65 T 06-07-2017 IPR032349 Protein of unknown function DUF4865 LK06_RS31960 9e55637f001b0f33aff1604fc12a152f 182 Pfam PF02371 Transposase IS116/IS110/IS902 family 57 131 1.1E-8 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 LK06_RS28510 b4260615fa28810300c7e70861b87450 358 SUPERFAMILY SSF103481 40 115 9.94E-5 T 06-07-2017 LK06_RS02450 df535d991668e18f732904a27c48e169 172 Gene3D G3DSA:3.40.630.30 8 166 1.8E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS02450 df535d991668e18f732904a27c48e169 172 SUPERFAMILY SSF55729 8 162 1.91E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS02450 df535d991668e18f732904a27c48e169 172 Pfam PF13302 Acetyltransferase (GNAT) domain 13 153 2.1E-22 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS15335 e6da8bfd1109eb4d740131203ecce7a3 164 Pfam PF04525 LURP-one-related 3 152 1.8E-27 T 06-07-2017 IPR007612 LURP1-related protein domain LK06_RS15335 e6da8bfd1109eb4d740131203ecce7a3 164 SUPERFAMILY SSF54518 1 152 4.97E-31 T 06-07-2017 IPR025659 Tubby C-terminal-like domain LK06_RS31755 16c27573448be48b07b80989db88c3ad 90 Pfam PF00550 Phosphopantetheine attachment site 9 70 8.4E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31755 16c27573448be48b07b80989db88c3ad 90 Gene3D G3DSA:1.10.1200.10 3 81 5.2E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS31755 16c27573448be48b07b80989db88c3ad 90 SUPERFAMILY SSF47336 2 82 5.04E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS32375 c75450176fbf4d9b6c8268478e6f2025 432 Pfam PF16289 Domain of unknown function (DUF4935) 34 226 1.3E-9 T 06-07-2017 IPR032557 Protein of unknown function DUF4935 LK06_RS24525 e2ec2deaf36dedac8808583a20b7908d 370 Pfam PF04055 Radical SAM superfamily 126 297 1.7E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 LK06_RS24525 e2ec2deaf36dedac8808583a20b7908d 370 PIRSF PIRSF006004 16 370 4.6E-124 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS24525 e2ec2deaf36dedac8808583a20b7908d 370 SUPERFAMILY SSF102114 115 344 1.57E-16 T 06-07-2017 LK06_RS24525 e2ec2deaf36dedac8808583a20b7908d 370 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 22 369 2.7E-96 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS24525 e2ec2deaf36dedac8808583a20b7908d 370 Gene3D G3DSA:3.20.20.70 122 342 4.6E-16 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS24525 e2ec2deaf36dedac8808583a20b7908d 370 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 21 370 66.244 T 06-07-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS21580 9a5370afdca50d449c74817f99806b34 60 Gene3D G3DSA:1.10.10.10 6 54 1.2E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS21580 9a5370afdca50d449c74817f99806b34 60 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 53 1.2E-8 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 LK06_RS21580 9a5370afdca50d449c74817f99806b34 60 Pfam PF12728 Helix-turn-helix domain 6 54 4.6E-11 T 06-07-2017 LK06_RS21580 9a5370afdca50d449c74817f99806b34 60 SUPERFAMILY SSF46955 5 53 2.38E-6 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS24970 90dc17c0e8f07d4b7b49ee25fccdf167 226 SUPERFAMILY SSF52172 3 144 1.71E-37 T 06-07-2017 IPR011006 CheY-like superfamily LK06_RS24970 90dc17c0e8f07d4b7b49ee25fccdf167 226 SMART SM00448 5 119 7.4E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS24970 90dc17c0e8f07d4b7b49ee25fccdf167 226 Gene3D G3DSA:3.40.50.2300 3 128 6.5E-36 T 06-07-2017 LK06_RS24970 90dc17c0e8f07d4b7b49ee25fccdf167 226 Pfam PF00072 Response regulator receiver domain 7 119 1.5E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LK06_RS22940 d8f6a6bde278980b575b4efd5a4ac1a5 601 Pfam PF12696 TraM recognition site of TraD and TraG 414 535 1.1E-22 T 06-07-2017 IPR032689 TraD/TraG, TraM recognition site LK06_RS22940 d8f6a6bde278980b575b4efd5a4ac1a5 601 Gene3D G3DSA:3.40.50.300 360 559 1.2E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22940 d8f6a6bde278980b575b4efd5a4ac1a5 601 Gene3D G3DSA:3.40.50.300 130 221 1.2E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS22940 d8f6a6bde278980b575b4efd5a4ac1a5 601 SUPERFAMILY SSF52540 135 559 7.96E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS00580 061082c4c40592c0981a637026f4a02c 609 Pfam PF04185 Phosphoesterase family 50 506 1.5E-77 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 LK06_RS06730 cd1c89618443029529bf92e4e0815513 299 SUPERFAMILY SSF110581 2 297 6.15E-101 T 06-07-2017 LK06_RS06730 cd1c89618443029529bf92e4e0815513 299 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 4 298 39.557 T 06-07-2017 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 LK06_RS06730 cd1c89618443029529bf92e4e0815513 299 Pfam PF04227 Indigoidine synthase A like protein 5 294 3.1E-113 T 06-07-2017 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 LK06_RS15575 70ef5cee82cd87b857b12d87317de0c0 482 Pfam PF01098 Cell cycle protein 87 460 2.1E-78 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 LK06_RS04715 1d285d1bf8e94887ac672e1c96b9bd0b 277 Gene3D G3DSA:1.25.40.10 19 251 1.2E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS04715 1d285d1bf8e94887ac672e1c96b9bd0b 277 SUPERFAMILY SSF48452 140 242 6.45E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS04715 1d285d1bf8e94887ac672e1c96b9bd0b 277 SUPERFAMILY SSF48452 19 126 3.8E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS21840 ba3b87d8c3c6ad51399f7c22df3d3e16 57 Pfam PF07282 Putative transposase DNA-binding domain 1 22 4.4E-6 T 06-07-2017 IPR010095 Transposase IS605, OrfB, C-terminal LK06_RS31345 3eb2b54ca78dd47450baaf688dd1bc96 302 Pfam PF03773 Predicted permease 20 298 5.3E-47 T 06-07-2017 IPR005524 Predicted permease DUF318 LK06_RS23030 8a78421073d43dc3c1eee01645d69a01 518 SUPERFAMILY SSF52540 85 479 3.44E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23030 8a78421073d43dc3c1eee01645d69a01 518 Gene3D G3DSA:3.40.50.300 114 198 6.2E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23030 8a78421073d43dc3c1eee01645d69a01 518 Gene3D G3DSA:3.40.50.300 332 453 6.2E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31930 2fef26badd7151023dc1049fd0cfb246 349 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 38 324 1.4E-33 T 06-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain LK06_RS31930 2fef26badd7151023dc1049fd0cfb246 349 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 155 327 1.0E-16 T 06-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain LK06_RS06515 dea6fdbed34af2f8f5c3cea76755268d 368 Pfam PF04909 Amidohydrolase 195 367 1.8E-12 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS06515 dea6fdbed34af2f8f5c3cea76755268d 368 Gene3D G3DSA:3.20.20.140 1 368 2.7E-113 T 06-07-2017 LK06_RS06515 dea6fdbed34af2f8f5c3cea76755268d 368 SUPERFAMILY SSF51556 169 368 6.74E-12 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS13210 469518a189f4f8eb77d19f032d4d5edc 229 Gene3D G3DSA:3.40.50.620 29 163 2.0E-42 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS13210 469518a189f4f8eb77d19f032d4d5edc 229 Pfam PF02698 DUF218 domain 45 157 6.9E-20 T 06-07-2017 IPR003848 Domain of unknown function DUF218 LK06_RS14520 540f2956c1e491fad9d257a906b0f6cb 451 SUPERFAMILY SSF53383 15 443 3.84E-118 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS14520 540f2956c1e491fad9d257a906b0f6cb 451 Pfam PF00202 Aminotransferase class-III 34 443 4.6E-98 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS14520 540f2956c1e491fad9d257a906b0f6cb 451 Gene3D G3DSA:3.90.1150.10 320 444 1.1E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS14520 540f2956c1e491fad9d257a906b0f6cb 451 Gene3D G3DSA:3.40.640.10 68 319 1.4E-79 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS14520 540f2956c1e491fad9d257a906b0f6cb 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LK06_RS06220 1a54fbdc8d7fb412f3dadd203e22dd78 419 Pfam PF01384 Phosphate transporter family 22 156 6.4E-32 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 LK06_RS06220 1a54fbdc8d7fb412f3dadd203e22dd78 419 Pfam PF01384 Phosphate transporter family 168 322 3.5E-45 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 LK06_RS01690 e645c9017dc7342cb6033ad6822ba6b2 473 Pfam PF06762 Lipase maturation factor 121 267 4.2E-57 T 06-07-2017 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 LK06_RS01690 e645c9017dc7342cb6033ad6822ba6b2 473 Pfam PF06762 Lipase maturation factor 277 465 7.0E-63 T 06-07-2017 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 LK06_RS25845 977e26d3ed0aca4b0b8e74ce56906571 315 Gene3D G3DSA:3.90.550.10 5 217 2.8E-45 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS25845 977e26d3ed0aca4b0b8e74ce56906571 315 Pfam PF00535 Glycosyl transferase family 2 8 120 2.4E-27 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS25845 977e26d3ed0aca4b0b8e74ce56906571 315 SUPERFAMILY SSF53448 5 221 2.44E-45 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS26650 5eac295f932d4cb7d554b3206ca33190 243 SUPERFAMILY SSF54909 23 242 7.24E-76 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel LK06_RS26650 5eac295f932d4cb7d554b3206ca33190 243 Gene3D G3DSA:3.30.70.1100 145 242 2.9E-40 T 06-07-2017 LK06_RS26650 5eac295f932d4cb7d554b3206ca33190 243 Pfam PF06778 Chlorite dismutase 45 232 6.8E-74 T 06-07-2017 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase LK06_RS26650 5eac295f932d4cb7d554b3206ca33190 243 Gene3D G3DSA:3.30.70.1030 29 144 3.9E-29 T 06-07-2017 LK06_RS19855 1cd1ebdacecfcf1376219a64650d8927 164 Pfam PF14433 SUKH-3 immunity protein 11 155 2.0E-47 T 06-07-2017 IPR025850 SUKH-3 immunity protein LK06_RS32325 f6e55a038bee47541e8d64f7732f1060 206 Pfam PF01548 Transposase 20 174 2.7E-22 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 LK06_RS16085 87c7b530180361d6a7d3261cb17fbea3 70 ProDom PD267558 MEMBRANE TRANSMEMBRANE SPANNING SCO3924 1 70 4.0E-18 T 06-07-2017 IPR020246 Uncharacterised protein family SCO3924 LK06_RS10020 670315a389994cdbb6f825d083229a10 594 Gene3D G3DSA:3.60.21.10 127 213 1.1E-65 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS10020 670315a389994cdbb6f825d083229a10 594 Gene3D G3DSA:3.60.21.10 272 287 1.1E-65 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS10020 670315a389994cdbb6f825d083229a10 594 Gene3D G3DSA:3.60.21.10 358 536 1.1E-65 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS10020 670315a389994cdbb6f825d083229a10 594 SUPERFAMILY SSF56300 128 213 8.95E-33 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS10020 670315a389994cdbb6f825d083229a10 594 SUPERFAMILY SSF56300 392 529 8.95E-33 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS10020 670315a389994cdbb6f825d083229a10 594 SUPERFAMILY SSF56300 272 299 8.95E-33 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS10020 670315a389994cdbb6f825d083229a10 594 TIGRFAM TIGR03767 P_acnes_RR: metallophosphoesterase, PPA1498 family 92 592 2.3E-216 T 06-07-2017 IPR022506 Metallophosphoesterase, PPA1498 LK06_RS10020 670315a389994cdbb6f825d083229a10 594 Pfam PF00149 Calcineurin-like phosphoesterase 128 492 2.4E-4 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 LK06_RS08745 7352154e6bb9ae8d4a60fb1c465da347 270 Gene3D G3DSA:3.40.50.1000 181 227 8.5E-9 T 06-07-2017 IPR023214 HAD-like domain LK06_RS08745 7352154e6bb9ae8d4a60fb1c465da347 270 Gene3D G3DSA:3.40.50.1000 3 105 8.5E-9 T 06-07-2017 IPR023214 HAD-like domain LK06_RS08745 7352154e6bb9ae8d4a60fb1c465da347 270 SUPERFAMILY SSF56784 1 14 1.88E-15 T 06-07-2017 IPR023214 HAD-like domain LK06_RS08745 7352154e6bb9ae8d4a60fb1c465da347 270 SUPERFAMILY SSF56784 41 230 1.88E-15 T 06-07-2017 IPR023214 HAD-like domain LK06_RS08745 7352154e6bb9ae8d4a60fb1c465da347 270 PIRSF PIRSF030802 1 237 5.1E-14 T 06-07-2017 IPR024197 Uncharacterised conserved protein UCP030802 LK06_RS15650 3e5501100c9821c904a3a0e3cb4fc0a4 286 SUPERFAMILY SSF103473 4 155 3.79E-16 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS15650 3e5501100c9821c904a3a0e3cb4fc0a4 286 Pfam PF07690 Major Facilitator Superfamily 11 157 1.4E-11 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS15650 3e5501100c9821c904a3a0e3cb4fc0a4 286 Gene3D G3DSA:1.20.1250.20 10 155 4.6E-14 T 06-07-2017 LK06_RS19640 ac1ca4f41f847a39c34a46d8c35e0227 386 Gene3D G3DSA:3.40.710.10 246 382 3.9E-76 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS19640 ac1ca4f41f847a39c34a46d8c35e0227 386 Gene3D G3DSA:3.40.710.10 6 214 3.9E-76 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS19640 ac1ca4f41f847a39c34a46d8c35e0227 386 Pfam PF00144 Beta-lactamase 26 378 1.7E-68 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS19640 ac1ca4f41f847a39c34a46d8c35e0227 386 SUPERFAMILY SSF56601 8 381 3.22E-66 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS00105 e240814d29df7f68bb9934ecd75d8b01 152 Gene3D G3DSA:2.60.120.10 11 121 2.4E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS00105 e240814d29df7f68bb9934ecd75d8b01 152 Pfam PF00027 Cyclic nucleotide-binding domain 26 112 3.1E-10 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain LK06_RS00105 e240814d29df7f68bb9934ecd75d8b01 152 SUPERFAMILY SSF51206 8 125 7.73E-21 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like LK06_RS30345 276f437c9ceb58c9e67c8623e69542de 342 Pfam PF06089 L-asparaginase II 26 328 3.3E-111 T 06-07-2017 IPR010349 L-asparaginase II LK06_RS23350 0cffe98c9594c5fd9a9ce006d0388619 249 Pfam PF01061 ABC-2 type transporter 11 212 9.6E-28 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS23350 0cffe98c9594c5fd9a9ce006d0388619 249 PIRSF PIRSF006648 2 248 1.5E-42 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS14580 b226e135858e3d7691b9e4512142d1bb 64 Pfam PF04149 Domain of unknown function (DUF397) 8 57 1.2E-19 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS17830 7ca5bc46bb1fbd38af6aad12c310f1d6 82 Pfam PF14026 Protein of unknown function (DUF4242) 4 78 4.1E-24 T 06-07-2017 IPR025336 Protein of unknown function DUF4242 LK06_RS24785 d3ec332eba457a705ef27d70ee363c89 1181 SUPERFAMILY SSF50494 6 196 4.4E-12 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS24785 d3ec332eba457a705ef27d70ee363c89 1181 SUPERFAMILY SSF52540 243 388 1.98E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11495 55dc3f1e54d364678aa556ca86e09a60 264 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 216 259 1.4E-10 T 06-07-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal LK06_RS11495 55dc3f1e54d364678aa556ca86e09a60 264 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 140 188 1.5E-11 T 06-07-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal LK06_RS11495 55dc3f1e54d364678aa556ca86e09a60 264 Gene3D G3DSA:3.30.160.100 23 105 8.5E-9 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 LK06_RS11495 55dc3f1e54d364678aa556ca86e09a60 264 SUPERFAMILY SSF69754 23 102 1.31E-9 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 LK06_RS10515 4d999e6e132759c932ab38780bf3a34e 67 Pfam PF12728 Helix-turn-helix domain 12 61 6.2E-10 T 06-07-2017 LK06_RS12795 5c4dd221c62791b85d427e4f8f2715fb 84 Pfam PF00550 Phosphopantetheine attachment site 8 57 3.3E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS12795 5c4dd221c62791b85d427e4f8f2715fb 84 Gene3D G3DSA:1.10.1200.10 7 75 5.4E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS12795 5c4dd221c62791b85d427e4f8f2715fb 84 ProSitePatterns PS00012 Phosphopantetheine attachment site. 27 42 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site LK06_RS12795 5c4dd221c62791b85d427e4f8f2715fb 84 SUPERFAMILY SSF47336 11 76 2.62E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain LK06_RS29010 1c9a9e058d5c10ae150e69918527abd8 128 Gene3D G3DSA:1.10.10.10 6 76 4.5E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29010 1c9a9e058d5c10ae150e69918527abd8 128 SUPERFAMILY SSF46785 7 80 2.85E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS29010 1c9a9e058d5c10ae150e69918527abd8 128 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 7.8E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS29010 1c9a9e058d5c10ae150e69918527abd8 128 SMART SM00345 17 76 8.8E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LK06_RS30120 1478e6932354fc4a6d1865f3b768a3f7 437 Pfam PF02342 TerD domain 5 172 8.4E-40 T 06-07-2017 IPR003325 TerD domain GO:0006950 LK06_RS30120 1478e6932354fc4a6d1865f3b768a3f7 437 Gene3D G3DSA:2.60.60.30 18 170 1.4E-31 T 06-07-2017 LK06_RS30120 1478e6932354fc4a6d1865f3b768a3f7 437 Gene3D G3DSA:2.60.60.30 255 360 6.0E-5 T 06-07-2017 LK06_RS30120 1478e6932354fc4a6d1865f3b768a3f7 437 PIRSF PIRSF037118 4 437 9.6E-165 T 06-07-2017 IPR017115 Tellurite resistance, TerA LK06_RS17630 9a1b6847b6d05d01d0771b93d68a3d81 87 Pfam PF11298 Protein of unknown function (DUF3099) 3 60 6.8E-8 T 06-07-2017 IPR021449 Protein of unknown function DUF3099 LK06_RS09020 30df8db4cc9baed4fd06df4b404a5386 170 SUPERFAMILY SSF55874 56 162 5.85E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS09020 30df8db4cc9baed4fd06df4b404a5386 170 Gene3D G3DSA:3.30.565.10 59 166 1.5E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS09020 30df8db4cc9baed4fd06df4b404a5386 170 Pfam PF13581 Histidine kinase-like ATPase domain 48 157 6.1E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS13805 a1e0e42b4c79cb8071bc13bc74568fa9 186 Gene3D G3DSA:3.40.50.2020 4 184 5.7E-82 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS13805 a1e0e42b4c79cb8071bc13bc74568fa9 186 SUPERFAMILY SSF53271 7 184 1.84E-56 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like LK06_RS13805 a1e0e42b4c79cb8071bc13bc74568fa9 186 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 15 179 4.1E-66 T 06-07-2017 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 LK06_RS13805 a1e0e42b4c79cb8071bc13bc74568fa9 186 Pfam PF00156 Phosphoribosyl transferase domain 22 166 3.7E-25 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 LK06_RS08915 5fa1053d719f63be4935498eaf171865 216 Pfam PF14273 Domain of unknown function (DUF4360) 35 213 1.3E-67 T 06-07-2017 IPR025649 Protein of unknown function DUF4360 LK06_RS10940 3c444a6082f54c3c8c2a76dd0596485b 164 SUPERFAMILY SSF50891 7 149 1.9E-8 T 06-07-2017 IPR029000 Cyclophilin-like domain LK06_RS10940 3c444a6082f54c3c8c2a76dd0596485b 164 Pfam PF12903 Protein of unknown function (DUF3830) 8 163 2.3E-62 T 06-07-2017 IPR024532 Protein of unknown function DUF3830 LK06_RS10120 df1b00d3f1c4b0b1c9c7ed7bcf465edd 313 SUPERFAMILY SSF161098 59 299 7.98E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10120 df1b00d3f1c4b0b1c9c7ed7bcf465edd 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 295 1.2E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10120 df1b00d3f1c4b0b1c9c7ed7bcf465edd 313 Gene3D G3DSA:1.10.3720.10 9 302 4.4E-55 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS02385 e8a9620ea7c57dbf19d1002acb5f51a0 421 SUPERFAMILY SSF53098 10 411 1.21E-31 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS02385 e8a9620ea7c57dbf19d1002acb5f51a0 421 Pfam PF13546 DDE superfamily endonuclease 20 290 1.2E-90 T 06-07-2017 LK06_RS01385 e8a9620ea7c57dbf19d1002acb5f51a0 421 SUPERFAMILY SSF53098 10 411 1.21E-31 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS01385 e8a9620ea7c57dbf19d1002acb5f51a0 421 Pfam PF13546 DDE superfamily endonuclease 20 290 1.2E-90 T 06-07-2017 LK06_RS02565 ec0430b15bf1b465c5d3253d752efdf1 74 SUPERFAMILY SSF109854 1 58 4.3E-5 T 06-07-2017 LK06_RS02565 ec0430b15bf1b465c5d3253d752efdf1 74 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 1 53 1.1E-5 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 LK06_RS20595 d898714b264d253b178852b575f0b2d9 526 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 5 522 1.1E-236 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS20595 d898714b264d253b178852b575f0b2d9 526 Pfam PF01642 Methylmalonyl-CoA mutase 6 518 5.7E-220 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS20595 d898714b264d253b178852b575f0b2d9 526 Gene3D G3DSA:3.20.20.240 5 520 1.1E-224 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS20595 d898714b264d253b178852b575f0b2d9 526 SUPERFAMILY SSF51703 3 520 3.14E-208 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 LK06_RS04750 52b042c4162448e610fbd6c28cecfa99 66 SUPERFAMILY SSF103481 7 64 2.48E-6 T 06-07-2017 LK06_RS04725 5b64476476fabbc6c34aa79d2903b5f4 316 Pfam PF00535 Glycosyl transferase family 2 4 169 7.1E-34 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LK06_RS04725 5b64476476fabbc6c34aa79d2903b5f4 316 Gene3D G3DSA:3.90.550.10 1 131 3.8E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS04725 5b64476476fabbc6c34aa79d2903b5f4 316 SUPERFAMILY SSF53448 1 179 3.15E-38 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases LK06_RS29640 281f762053c19610deb98a7f8746baf8 199 Pfam PF08241 Methyltransferase domain 46 141 6.7E-19 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS29640 281f762053c19610deb98a7f8746baf8 199 SUPERFAMILY SSF53335 3 181 2.95E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS29640 281f762053c19610deb98a7f8746baf8 199 Gene3D G3DSA:3.40.50.150 6 186 9.4E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS24565 b9c87073c74ac9cb34235aef216cf653 246 SUPERFAMILY SSF52540 10 233 1.45E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24565 b9c87073c74ac9cb34235aef216cf653 246 SMART SM00382 35 226 2.7E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS24565 b9c87073c74ac9cb34235aef216cf653 246 Gene3D G3DSA:3.40.50.300 10 226 7.4E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24565 b9c87073c74ac9cb34235aef216cf653 246 Pfam PF00005 ABC transporter 27 175 1.4E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS25135 96c1c187a0e4162ea1d81ef37c7c6554 289 SUPERFAMILY SSF54506 5 136 1.94E-34 T 06-07-2017 LK06_RS25135 96c1c187a0e4162ea1d81ef37c7c6554 289 Pfam PF01678 Diaminopimelate epimerase 7 135 3.0E-35 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 LK06_RS25135 96c1c187a0e4162ea1d81ef37c7c6554 289 Pfam PF01678 Diaminopimelate epimerase 153 274 8.2E-29 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 LK06_RS25135 96c1c187a0e4162ea1d81ef37c7c6554 289 Gene3D G3DSA:3.10.310.10 132 269 6.8E-40 T 06-07-2017 LK06_RS25135 96c1c187a0e4162ea1d81ef37c7c6554 289 SUPERFAMILY SSF54506 142 279 4.04E-36 T 06-07-2017 LK06_RS25135 96c1c187a0e4162ea1d81ef37c7c6554 289 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 5 281 31.867 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 LK06_RS25135 96c1c187a0e4162ea1d81ef37c7c6554 289 Gene3D G3DSA:3.10.310.10 6 131 1.3E-39 T 06-07-2017 LK06_RS25135 96c1c187a0e4162ea1d81ef37c7c6554 289 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 279 5.4E-68 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 LK06_RS25135 96c1c187a0e4162ea1d81ef37c7c6554 289 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 76 90 - T 06-07-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 LK06_RS07100 f6be4265da9b5b480bd1e55a8d060d75 407 Gene3D G3DSA:3.40.50.200 83 402 2.3E-61 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS07100 f6be4265da9b5b480bd1e55a8d060d75 407 SUPERFAMILY SSF52743 81 404 1.13E-38 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LK06_RS07100 f6be4265da9b5b480bd1e55a8d060d75 407 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 332 342 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site LK06_RS08600 914f29e48e35291c165788fa93ca4e96 137 Gene3D G3DSA:1.10.530.10 62 124 5.1E-9 T 06-07-2017 LK06_RS08600 914f29e48e35291c165788fa93ca4e96 137 Pfam PF01464 Transglycosylase SLT domain 62 125 1.0E-8 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 LK06_RS08600 914f29e48e35291c165788fa93ca4e96 137 SUPERFAMILY SSF53955 64 124 9.29E-12 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS07975 40a0f07608a1e0d847a709d3a5461c3b 263 Pfam PF02517 CAAX protease self-immunity 160 247 7.3E-9 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 LK06_RS02435 cd368419daa31f5c9e314438f9276169 154 Pfam PF08388 Group II intron, maturase-specific domain 83 129 2.5E-9 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS01510 45054364267ec98bf2b9aa4e9ea09750 497 Pfam PF15975 Flotillin 363 464 3.8E-10 T 06-07-2017 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 LK06_RS01510 45054364267ec98bf2b9aa4e9ea09750 497 Pfam PF01145 SPFH domain / Band 7 family 29 214 2.8E-22 T 06-07-2017 IPR001107 Band 7 domain LK06_RS01510 45054364267ec98bf2b9aa4e9ea09750 497 SUPERFAMILY SSF117892 65 205 6.41E-25 T 06-07-2017 IPR001107 Band 7 domain LK06_RS30000 398174d07955525f7c794ef030f73f9f 149 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 35 114 5.5E-14 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 LK06_RS30000 398174d07955525f7c794ef030f73f9f 149 Pfam PF04075 Domain of unknown function (DUF385) 33 110 1.8E-10 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 LK06_RS26010 f68a434427033e916f7e1c632098e264 285 Pfam PF00296 Luciferase-like monooxygenase 5 248 2.4E-40 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS26010 f68a434427033e916f7e1c632098e264 285 SUPERFAMILY SSF51679 3 277 3.53E-51 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS26010 f68a434427033e916f7e1c632098e264 285 Gene3D G3DSA:3.20.20.30 4 277 8.5E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS12715 e18b7dd2feab03090500894121d21081 284 Gene3D G3DSA:3.40.50.720 1 217 1.1E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12715 e18b7dd2feab03090500894121d21081 284 Pfam PF13460 NAD(P)H-binding 7 183 1.8E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS12715 e18b7dd2feab03090500894121d21081 284 SUPERFAMILY SSF51735 3 255 2.79E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS25500 29448c6838ba9c13d7e6a1b7279d90f2 132 Gene3D G3DSA:2.40.50.140 42 126 4.6E-10 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS25500 29448c6838ba9c13d7e6a1b7279d90f2 132 PIRSF PIRSF006910 1 129 6.9E-57 T 06-07-2017 IPR016499 Nucleic acid binding protein, Rv2694c, predicted LK06_RS25500 29448c6838ba9c13d7e6a1b7279d90f2 132 SUPERFAMILY SSF50249 40 124 7.88E-5 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS24370 66e6f4b8af845eef9c29dbc92db77f9c 492 SUPERFAMILY SSF48452 232 353 1.04E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS24370 66e6f4b8af845eef9c29dbc92db77f9c 492 SUPERFAMILY SSF48452 413 448 1.04E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS24370 66e6f4b8af845eef9c29dbc92db77f9c 492 Gene3D G3DSA:1.25.40.10 234 480 1.5E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS27925 46739578509814317b8356f789d46e22 285 SUPERFAMILY SSF51730 5 262 2.35E-36 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like LK06_RS27925 46739578509814317b8356f789d46e22 285 Gene3D G3DSA:3.20.20.220 6 263 9.4E-32 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like LK06_RS11140 744c62df6542ff9851390042c65988d9 258 Pfam PF06182 ABC-2 family transporter protein 26 257 6.3E-65 T 06-07-2017 IPR010390 Protein of unknown function DUF990 LK06_RS31630 5e8d71f1d376175a48cf335fbdfaa676 355 Gene3D G3DSA:3.40.50.2300 36 157 1.8E-31 T 06-07-2017 LK06_RS31630 5e8d71f1d376175a48cf335fbdfaa676 355 Gene3D G3DSA:3.40.50.2300 158 328 2.4E-37 T 06-07-2017 LK06_RS31630 5e8d71f1d376175a48cf335fbdfaa676 355 SUPERFAMILY SSF53822 35 329 3.93E-62 T 06-07-2017 IPR028082 Periplasmic binding protein-like I LK06_RS31630 5e8d71f1d376175a48cf335fbdfaa676 355 Pfam PF13407 Periplasmic binding protein domain 39 299 1.8E-58 T 06-07-2017 IPR025997 Periplasmic binding protein LK06_RS13115 beb90429c69d7af7a53516c17f3ae367 430 Gene3D G3DSA:3.20.20.370 79 395 5.2E-13 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS13115 beb90429c69d7af7a53516c17f3ae367 430 SUPERFAMILY SSF88713 159 394 2.7E-27 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS13115 beb90429c69d7af7a53516c17f3ae367 430 SUPERFAMILY SSF88713 81 129 2.7E-27 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS08010 a73687937069145bca5f3d43d0c6557d 446 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 46 431 1.5E-137 T 06-07-2017 IPR018721 Protein of unknown function DUF2252 LK06_RS24520 5fc7a5132b3098d492795111dee6ff1d 148 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 140 1.6E-19 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase LK06_RS24520 5fc7a5132b3098d492795111dee6ff1d 148 Gene3D G3DSA:3.30.530.20 4 130 4.9E-17 T 06-07-2017 IPR023393 START-like domain LK06_RS24520 5fc7a5132b3098d492795111dee6ff1d 148 SUPERFAMILY SSF55961 2 145 1.62E-27 T 06-07-2017 LK06_RS16455 1b37a48d04e470787acaa53d457872d5 226 Gene3D G3DSA:3.10.490.10 14 193 1.7E-6 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like LK06_RS05155 4c72cc28b679f57b2262aae02172574c 262 SUPERFAMILY SSF47240 15 170 3.02E-8 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS08520 b22a1603b8c531d37d8fdeca4780f7b5 277 SUPERFAMILY SSF161098 7 277 3.27E-72 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS08520 b22a1603b8c531d37d8fdeca4780f7b5 277 Gene3D G3DSA:1.10.3720.10 12 264 9.7E-64 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS08520 b22a1603b8c531d37d8fdeca4780f7b5 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 269 9.5E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS14470 993877920d8ced812c7581509c7b0bfe 266 Pfam PF02104 SURF1 family 22 228 1.6E-20 T 06-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS27015 a0a0b5932ace14b2cbb59cfa213936ff 289 Gene3D G3DSA:3.20.20.60 4 256 4.9E-56 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS27015 a0a0b5932ace14b2cbb59cfa213936ff 289 Pfam PF13714 Phosphoenolpyruvate phosphomutase 16 244 1.0E-32 T 06-07-2017 LK06_RS27015 a0a0b5932ace14b2cbb59cfa213936ff 289 SUPERFAMILY SSF51621 4 250 7.18E-59 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 LK06_RS03505 a42f61956508191d3a1fac59c091bcdc 134 Pfam PF05621 Bacterial TniB protein 1 110 9.3E-13 T 06-07-2017 IPR008868 Bacterial TniB LK06_RS19390 4ca80da6b7b54c081c598002a48dfb12 213 Pfam PF13302 Acetyltransferase (GNAT) domain 5 152 4.5E-17 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS19390 4ca80da6b7b54c081c598002a48dfb12 213 SUPERFAMILY SSF55729 3 176 1.56E-41 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS19390 4ca80da6b7b54c081c598002a48dfb12 213 Gene3D G3DSA:3.40.630.30 3 182 5.5E-58 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS00970 9488b01feb257e696eaf7f6f3a12d4c9 406 SUPERFAMILY SSF53300 219 350 4.62E-15 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS00970 9488b01feb257e696eaf7f6f3a12d4c9 406 Pfam PF05762 VWA domain containing CoxE-like protein 167 382 1.1E-62 T 06-07-2017 IPR008912 Uncharacterised protein family CoxE-like LK06_RS00970 9488b01feb257e696eaf7f6f3a12d4c9 406 SMART SM00327 220 387 1.3E-6 T 06-07-2017 IPR002035 von Willebrand factor, type A LK06_RS00970 9488b01feb257e696eaf7f6f3a12d4c9 406 PIRSF PIRSF010256 17 392 1.1E-99 T 06-07-2017 IPR011195 Uncharacterised conserved protein UCP010256 LK06_RS19350 365c65fecf8af5160f7aeffccf1285e8 431 Pfam PF07690 Major Facilitator Superfamily 44 313 9.8E-14 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS19350 365c65fecf8af5160f7aeffccf1285e8 431 Gene3D G3DSA:1.20.1250.20 234 407 1.9E-9 T 06-07-2017 LK06_RS19350 365c65fecf8af5160f7aeffccf1285e8 431 Gene3D G3DSA:1.20.1250.20 30 206 5.7E-9 T 06-07-2017 LK06_RS19350 365c65fecf8af5160f7aeffccf1285e8 431 SUPERFAMILY SSF103473 23 407 1.22E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS04745 0334772bfdbc0974cee49aaa6f48327a 202 SUPERFAMILY SSF53254 5 184 1.39E-28 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS04745 0334772bfdbc0974cee49aaa6f48327a 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 25 185 2.2E-23 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS04745 0334772bfdbc0974cee49aaa6f48327a 202 SMART SM00855 4 151 0.0076 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS04745 0334772bfdbc0974cee49aaa6f48327a 202 Gene3D G3DSA:3.40.50.1240 11 183 1.1E-21 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS05660 58bb81ab0ecfd3d7500b4b87301439ee 254 Pfam PF10127 Predicted nucleotidyltransferase 17 224 3.4E-39 T 06-07-2017 IPR018775 Nucleotidyltransferase, predicted LK06_RS08780 08de044ed05aa50b0327a5bae1f1325d 191 Pfam PF02342 TerD domain 3 187 1.2E-87 T 06-07-2017 IPR003325 TerD domain GO:0006950 LK06_RS08780 08de044ed05aa50b0327a5bae1f1325d 191 Gene3D G3DSA:2.60.60.30 18 185 2.7E-76 T 06-07-2017 LK06_RS05255 28a994d4ad083292ea5220d85a44ff7d 349 Gene3D G3DSA:1.25.40.10 294 321 9.6E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS05255 28a994d4ad083292ea5220d85a44ff7d 349 Gene3D G3DSA:1.25.40.10 63 205 9.6E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS22170 0b19be04137698e2e647510c870a6a3a 249 Pfam PF12138 Spherulation-specific family 4 22 242 2.5E-14 T 06-07-2017 IPR021986 Spherulation-specific family 4 LK06_RS16845 2deb7de05412a963b510a4a33940ba43 150 Pfam PF15644 Papain fold toxin 1, glutamine deamidase 41 135 2.0E-15 T 06-07-2017 IPR028908 Tox-PL domain LK06_RS24240 1fe6e8ed1f7d3ff0e5b1b8c6f2bd9a30 261 Pfam PF08543 Phosphomethylpyrimidine kinase 12 254 2.8E-89 T 06-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 LK06_RS24240 1fe6e8ed1f7d3ff0e5b1b8c6f2bd9a30 261 SUPERFAMILY SSF53613 2 258 2.65E-76 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS24240 1fe6e8ed1f7d3ff0e5b1b8c6f2bd9a30 261 Gene3D G3DSA:3.40.1190.20 2 255 5.7E-98 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS24240 1fe6e8ed1f7d3ff0e5b1b8c6f2bd9a30 261 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 255 2.0E-92 T 06-07-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LK06_RS25225 af91e1f55323f04f5967ed81b96e44e0 301 SUPERFAMILY SSF101478 10 292 6.28E-50 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 LK06_RS25225 af91e1f55323f04f5967ed81b96e44e0 301 Pfam PF03747 ADP-ribosylglycohydrolase 17 275 1.4E-43 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 LK06_RS11825 96fc1bcf482de5dff846b55ab1e1d1dc 335 Pfam PF01944 Stage II sporulation protein M 109 283 4.1E-36 T 06-07-2017 IPR002798 Stage II sporulation protein M-like LK06_RS03615 c39bcd99761ab7cdf7efc945b73a5f41 142 SUPERFAMILY SSF50346 23 124 1.88E-24 T 06-07-2017 IPR011033 PRC-barrel-like LK06_RS03615 c39bcd99761ab7cdf7efc945b73a5f41 142 Gene3D G3DSA:2.30.30.240 27 66 4.1E-4 T 06-07-2017 LK06_RS03615 c39bcd99761ab7cdf7efc945b73a5f41 142 Pfam PF05239 PRC-barrel domain 27 90 6.7E-10 T 06-07-2017 IPR027275 PRC-barrel domain LK06_RS08080 6a0f6fc5c77c93d2ad9016ad86b01aef 229 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LK06_RS08080 6a0f6fc5c77c93d2ad9016ad86b01aef 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 3.9E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS08080 6a0f6fc5c77c93d2ad9016ad86b01aef 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS08080 6a0f6fc5c77c93d2ad9016ad86b01aef 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LK06_RS08080 6a0f6fc5c77c93d2ad9016ad86b01aef 229 Gene3D G3DSA:1.10.357.10 6 188 2.2E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 LK06_RS08080 6a0f6fc5c77c93d2ad9016ad86b01aef 229 SUPERFAMILY SSF46689 6 78 1.49E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS16605 0bba27010696e00fe0e23834c40daaf0 311 Pfam PF14342 Domain of unknown function (DUF4396) 83 219 1.0E-29 T 06-07-2017 IPR025509 Domain of unknown function DUF4396 LK06_RS29480 995d805edf4d3fac8851ab5427312c2a 322 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 42 283 3.0E-78 T 06-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related LK06_RS02475 089e7087df1d9d8de5674df2bd95bf7d 332 Pfam PF08012 Protein of unknown function (DUF1702) 5 321 3.0E-128 T 06-07-2017 IPR012964 Protein of unknown function DUF1702 LK06_RS03950 2a0796a8558c85b575ea5c9a4985e200 213 Pfam PF04973 Nicotinamide mononucleotide transporter 18 197 3.7E-43 T 06-07-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 LK06_RS18530 f1e8c4c48b9e0f2df1fb03a752b9bf04 89 Gene3D G3DSA:2.60.120.10 2 85 2.1E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS18530 f1e8c4c48b9e0f2df1fb03a752b9bf04 89 SUPERFAMILY SSF51182 3 83 4.67E-14 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS08635 218557871002d27bd288e6be203fd330 150 Pfam PF09350 Domain of unknown function (DUF1992) 14 77 9.3E-20 T 06-07-2017 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain LK06_RS26495 9ebf924d60cb50864f2358834ffc8388 638 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 149 228 1.6E-14 T 06-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 LK06_RS00605 f29851b162557043478a0fa9c1c1f4da 145 Pfam PF01475 Ferric uptake regulator family 16 129 2.1E-18 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 LK06_RS00605 f29851b162557043478a0fa9c1c1f4da 145 Gene3D G3DSA:1.10.10.10 10 84 1.4E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00605 f29851b162557043478a0fa9c1c1f4da 145 SUPERFAMILY SSF46785 11 137 4.12E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01450 560d6425c07a1dee1936b86a1ac6cd3f 216 Gene3D G3DSA:3.40.50.300 2 212 9.6E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01450 560d6425c07a1dee1936b86a1ac6cd3f 216 SMART SM00382 27 198 0.0067 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS01450 560d6425c07a1dee1936b86a1ac6cd3f 216 SUPERFAMILY SSF52540 3 211 3.79E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS01450 560d6425c07a1dee1936b86a1ac6cd3f 216 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LK06_RS01450 560d6425c07a1dee1936b86a1ac6cd3f 216 Pfam PF00005 ABC transporter 19 153 5.0E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS26915 80c3ef78159528e7720d3c9a457e856f 230 SUPERFAMILY SSF52833 29 190 6.27E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS26915 80c3ef78159528e7720d3c9a457e856f 230 Gene3D G3DSA:3.40.30.10 28 189 6.8E-13 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS26915 80c3ef78159528e7720d3c9a457e856f 230 Pfam PF01323 DSBA-like thioredoxin domain 33 188 2.3E-10 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 LK06_RS07630 a1a66d14a7421eade4798e0ba629650c 206 Gene3D G3DSA:1.20.120.80 25 205 4.8E-55 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07630 a1a66d14a7421eade4798e0ba629650c 206 Pfam PF00510 Cytochrome c oxidase subunit III 25 204 2.4E-24 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07630 a1a66d14a7421eade4798e0ba629650c 206 SUPERFAMILY SSF81452 9 205 6.41E-55 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS25305 2fa00c9b35306fcb5deae35e45c01009 172 Pfam PF07301 Protein of unknown function (DUF1453) 8 124 4.5E-6 T 06-07-2017 IPR009916 Protein of unknown function DUF1453 LK06_RS07730 f2ea5ab5c3a5f4f3b00a6e637353526b 233 Pfam PF08241 Methyltransferase domain 22 122 3.0E-19 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS07730 f2ea5ab5c3a5f4f3b00a6e637353526b 233 SUPERFAMILY SSF53335 7 150 8.14E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07730 f2ea5ab5c3a5f4f3b00a6e637353526b 233 Gene3D G3DSA:3.40.50.150 9 138 4.4E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26405 9d4d34bef4d0c4974aa7d0e5e07dc318 163 Pfam PF07681 DoxX 6 90 2.7E-10 T 06-07-2017 IPR032808 DoxX family LK06_RS28335 9807b1176c5bc5aa7d280f8df6607a1f 441 Pfam PF07690 Major Facilitator Superfamily 19 320 6.9E-33 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS28335 9807b1176c5bc5aa7d280f8df6607a1f 441 Gene3D G3DSA:1.20.1250.20 22 170 4.1E-23 T 06-07-2017 LK06_RS28335 9807b1176c5bc5aa7d280f8df6607a1f 441 SUPERFAMILY SSF103473 221 324 1.26E-39 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS28335 9807b1176c5bc5aa7d280f8df6607a1f 441 SUPERFAMILY SSF103473 18 177 1.26E-39 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS07850 64f77c9a5a54afecd09e0fccbf1fd025 488 Gene3D G3DSA:1.25.40.10 269 447 4.0E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS27160 c9dfb0166f69ada9a1750a191762cc06 272 Pfam PF01522 Polysaccharide deacetylase 73 192 1.8E-40 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS27160 c9dfb0166f69ada9a1750a191762cc06 272 SUPERFAMILY SSF88713 70 259 1.56E-60 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LK06_RS27160 c9dfb0166f69ada9a1750a191762cc06 272 Gene3D G3DSA:3.20.20.370 69 260 2.1E-63 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 LK06_RS31825 0eafaf6df559709a1e6f689682a949e5 374 Pfam PF03601 Conserved hypothetical protein 698 39 352 1.6E-72 T 06-07-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 LK06_RS20080 dd2f9e02bba5122c84604ab18aacb125 165 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 5 141 1.0E-31 T 06-07-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 LK06_RS20080 dd2f9e02bba5122c84604ab18aacb125 165 SUPERFAMILY SSF55729 5 145 3.9E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS20080 dd2f9e02bba5122c84604ab18aacb125 165 Gene3D G3DSA:3.40.630.30 2 143 1.3E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS20080 dd2f9e02bba5122c84604ab18aacb125 165 Pfam PF00583 Acetyltransferase (GNAT) family 50 121 4.0E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS01165 abc94beff3676db5d5c9904b00ea55db 177 Pfam PF02441 Flavoprotein 12 133 6.2E-10 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS01165 abc94beff3676db5d5c9904b00ea55db 177 SUPERFAMILY SSF52507 8 174 1.96E-26 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS01165 abc94beff3676db5d5c9904b00ea55db 177 Gene3D G3DSA:3.40.50.1950 11 174 3.4E-21 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LK06_RS21240 4fba6c485b7de103d5a57c1dd8e80dfe 129 SUPERFAMILY SSF55874 25 104 3.87E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS24600 802dcb7fdb44c834cf36720a8a3c9da8 227 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 219 2.9E-32 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 LK06_RS24600 802dcb7fdb44c834cf36720a8a3c9da8 227 Gene3D G3DSA:3.20.20.190 3 225 3.8E-50 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS24600 802dcb7fdb44c834cf36720a8a3c9da8 227 SUPERFAMILY SSF51695 5 223 1.17E-49 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS29635 d0d1cd0164f30da2e11f6c15ed931e4f 301 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 43 247 6.6E-19 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 LK06_RS08425 8fe86a30bbe6bdb411ef4c0e96365ace 279 Pfam PF02591 C4-type zinc ribbon domain 237 271 7.2E-11 T 06-07-2017 IPR003743 C4-type zinc ribbon domain LK06_RS26900 1f7537972507fe834d244ad673dab5bb 287 Pfam PF01636 Phosphotransferase enzyme family 36 234 2.8E-15 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase LK06_RS26900 1f7537972507fe834d244ad673dab5bb 287 SUPERFAMILY SSF56112 6 258 2.92E-31 T 06-07-2017 IPR011009 Protein kinase-like domain LK06_RS26900 1f7537972507fe834d244ad673dab5bb 287 Gene3D G3DSA:3.90.1200.10 93 272 3.2E-13 T 06-07-2017 LK06_RS05440 3029a898f5f1061c0a304c9cff395e02 268 Gene3D G3DSA:3.40.50.1110 37 257 5.1E-63 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS05440 3029a898f5f1061c0a304c9cff395e02 268 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 40 256 6.4E-22 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS05440 3029a898f5f1061c0a304c9cff395e02 268 SUPERFAMILY SSF52266 37 256 8.99E-59 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain LK06_RS26745 d96fe4b32d8d823ddfc4ea6f3ce1155f 433 SMART SM00331 206 415 3.8E-23 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS26745 d96fe4b32d8d823ddfc4ea6f3ce1155f 433 SUPERFAMILY SSF81606 219 414 1.67E-10 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS26745 d96fe4b32d8d823ddfc4ea6f3ce1155f 433 Gene3D G3DSA:3.30.450.40 41 183 6.6E-8 T 06-07-2017 IPR029016 GAF domain-like LK06_RS26745 d96fe4b32d8d823ddfc4ea6f3ce1155f 433 SMART SM00065 52 185 0.0027 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS26745 d96fe4b32d8d823ddfc4ea6f3ce1155f 433 SUPERFAMILY SSF55781 100 186 2.62E-8 T 06-07-2017 IPR029016 GAF domain-like LK06_RS26745 d96fe4b32d8d823ddfc4ea6f3ce1155f 433 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 234 414 2.2E-42 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS03550 ce156edea5620dad46d34b8c782d7586 535 Pfam PF14104 Domain of unknown function (DUF4277) 7 96 3.2E-15 T 06-07-2017 IPR025457 Domain of unknown function DUF4277 LK06_RS19900 9dca0ed884e09f07abd833f0d37303c6 777 SUPERFAMILY SSF53335 269 556 5.88E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS19900 9dca0ed884e09f07abd833f0d37303c6 777 Pfam PF02384 N-6 DNA Methylase 271 497 7.2E-31 T 06-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 LK06_RS19900 9dca0ed884e09f07abd833f0d37303c6 777 SUPERFAMILY SSF116734 645 766 1.29E-7 T 06-07-2017 LK06_RS19900 9dca0ed884e09f07abd833f0d37303c6 777 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 406 430 2.4E-12 T 06-07-2017 LK06_RS19900 9dca0ed884e09f07abd833f0d37303c6 777 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 372 384 2.4E-12 T 06-07-2017 LK06_RS19900 9dca0ed884e09f07abd833f0d37303c6 777 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 285 301 2.4E-12 T 06-07-2017 LK06_RS19900 9dca0ed884e09f07abd833f0d37303c6 777 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 307 321 2.4E-12 T 06-07-2017 LK06_RS19900 9dca0ed884e09f07abd833f0d37303c6 777 Gene3D G3DSA:3.40.50.150 283 459 1.6E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26540 592ca1118e55478d33e37629f55fd795 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 301 4.7E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26540 592ca1118e55478d33e37629f55fd795 307 Gene3D G3DSA:1.10.3720.10 32 295 1.1E-59 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS26540 592ca1118e55478d33e37629f55fd795 307 SUPERFAMILY SSF161098 33 304 3.4E-64 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS04945 fed2a320d3bb6f42b216452fe44958bc 525 SUPERFAMILY SSF55874 204 352 2.49E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04945 fed2a320d3bb6f42b216452fe44958bc 525 Gene3D G3DSA:3.30.565.10 243 351 3.8E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS04945 fed2a320d3bb6f42b216452fe44958bc 525 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 243 346 9.2E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS22540 e7b833e5279122618310de32cfa805c0 144 TIGRFAM TIGR02754 sod_Ni_protease: nickel-type superoxide dismutase maturation protease 21 103 2.8E-24 T 06-07-2017 IPR014124 Peptidase S26A, superoxide dismutase maturation protease, nickel-type LK06_RS22540 e7b833e5279122618310de32cfa805c0 144 Gene3D G3DSA:2.10.109.10 20 110 2.6E-18 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain LK06_RS22540 e7b833e5279122618310de32cfa805c0 144 SUPERFAMILY SSF51306 20 110 2.09E-22 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C LK06_RS22540 e7b833e5279122618310de32cfa805c0 144 Pfam PF00717 Peptidase S24-like 21 83 9.1E-10 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B LK06_RS31045 0c7803f31082fba0296dc895f640fb2d 312 Gene3D G3DSA:3.60.130.10 15 309 8.2E-80 T 06-07-2017 LK06_RS31045 0c7803f31082fba0296dc895f640fb2d 312 SUPERFAMILY SSF51197 19 308 1.88E-78 T 06-07-2017 LK06_RS31045 0c7803f31082fba0296dc895f640fb2d 312 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 20 301 6.2E-54 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 LK06_RS28640 9e1f607df6d9047e9e75755793c998bc 162 SUPERFAMILY SSF52949 4 156 1.88E-36 T 06-07-2017 LK06_RS28640 9e1f607df6d9047e9e75755793c998bc 162 SMART SM00506 3 141 7.6E-14 T 06-07-2017 IPR002589 Macro domain LK06_RS07870 350c9bb8de32c48dbd77df93b872ea27 234 Pfam PF13829 Domain of unknown function (DUF4191) 11 222 4.7E-83 T 06-07-2017 IPR025445 Protein of unknown function DUF4191 LK06_RS07870 350c9bb8de32c48dbd77df93b872ea27 234 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 1 233 3.0E-100 T 06-07-2017 LK06_RS31310 c423c2d8c15fa3a321538795409777b1 599 Pfam PF00374 Nickel-dependent hydrogenase 181 577 1.8E-46 T 06-07-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 LK06_RS31310 c423c2d8c15fa3a321538795409777b1 599 Pfam PF00374 Nickel-dependent hydrogenase 57 139 9.9E-18 T 06-07-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 LK06_RS31310 c423c2d8c15fa3a321538795409777b1 599 SUPERFAMILY SSF56762 21 577 1.01E-109 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS31310 c423c2d8c15fa3a321538795409777b1 599 Gene3D G3DSA:1.10.645.10 21 577 3.7E-148 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS24365 e53938f6d8573b9993b28955d6b128d4 220 SMART SM00943 27 206 1.2E-34 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal LK06_RS24365 e53938f6d8573b9993b28955d6b128d4 220 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 35 198 3.2E-15 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal LK06_RS11535 71692c46dbf194abd16a0c4c1bdcac09 462 SUPERFAMILY SSF103473 20 438 3.4E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS11535 71692c46dbf194abd16a0c4c1bdcac09 462 Pfam PF07690 Major Facilitator Superfamily 53 398 1.1E-19 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS11535 71692c46dbf194abd16a0c4c1bdcac09 462 Gene3D G3DSA:1.20.1250.20 48 218 5.5E-12 T 06-07-2017 LK06_RS11535 71692c46dbf194abd16a0c4c1bdcac09 462 Gene3D G3DSA:1.20.1250.20 240 435 3.3E-10 T 06-07-2017 LK06_RS09450 608e62f5d207c9a44739056ed023756b 359 Pfam PF02562 PhoH-like protein 128 331 1.7E-95 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 LK06_RS09450 608e62f5d207c9a44739056ed023756b 359 SUPERFAMILY SSF52540 121 308 1.69E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09450 608e62f5d207c9a44739056ed023756b 359 Gene3D G3DSA:3.40.50.300 127 331 8.3E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20805 5cad4241693087f905db0fe802be6f5c 221 Pfam PF10756 Bacterial PH domain 75 148 1.3E-8 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 LK06_RS18485 7b9b04fc4984f0b86babe25af09dc1f4 308 Pfam PF11228 Protein of unknown function (DUF3027) 36 261 1.8E-82 T 06-07-2017 IPR021391 Protein of unknown function DUF3027 LK06_RS11920 ce9087ef984bf4a8a3d12a3136b074c7 298 Gene3D G3DSA:1.10.340.30 110 225 1.3E-17 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS11920 ce9087ef984bf4a8a3d12a3136b074c7 298 SUPERFAMILY SSF48150 96 278 6.8E-28 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LK06_RS19345 74aa029a88f88128a6ef3d4e179a7597 110 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 7.0E-19 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LK06_RS19345 74aa029a88f88128a6ef3d4e179a7597 110 SMART SM00834 2 41 3.1E-13 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LK06_RS19345 74aa029a88f88128a6ef3d4e179a7597 110 Pfam PF09723 Zinc ribbon domain 2 40 6.0E-13 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LK06_RS28700 97480b974cfe2600f665696b8200b8d5 259 Pfam PF01066 CDP-alcohol phosphatidyltransferase 49 114 1.0E-9 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 SUPERFAMILY SSF81464 26 124 8.34E-19 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 263 280 2.6E-14 T 06-07-2017 LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 111 2.6E-14 T 06-07-2017 LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 135 154 2.6E-14 T 06-07-2017 LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 245 262 2.6E-14 T 06-07-2017 LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 225 245 2.6E-14 T 06-07-2017 LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 48 289 1.2E-48 T 06-07-2017 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 210 280 1.5E-17 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 Gene3D G3DSA:1.10.287.90 41 124 4.9E-15 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 Gene3D G3DSA:2.60.40.420 137 292 1.7E-40 T 06-07-2017 IPR008972 Cupredoxin LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 SUPERFAMILY SSF49503 135 158 2.51E-40 T 06-07-2017 IPR008972 Cupredoxin LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 SUPERFAMILY SSF49503 203 299 2.51E-40 T 06-07-2017 IPR008972 Cupredoxin LK06_RS07655 92b55231614099f8d6e21e0da29c7556 320 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 226 274 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LK06_RS05585 83425338c7f52aa21d62e7bc296d5b3f 145 Pfam PF04472 Protein of unknown function (DUF552) 59 128 1.9E-24 T 06-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 LK06_RS05585 83425338c7f52aa21d62e7bc296d5b3f 145 Hamap MF_01197 Cell division protein SepF [sepF]. 1 136 19.355 T 06-07-2017 IPR023052 Cell division protein SepF GO:0090529 LK06_RS30675 c6e18b1df97b75a72675e3c90bb329ad 238 Pfam PF03777 Small secreted domain (DUF320) 28 83 6.7E-27 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS30675 c6e18b1df97b75a72675e3c90bb329ad 238 Pfam PF03777 Small secreted domain (DUF320) 98 152 2.2E-23 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS01615 3ff9886978a3615736c133aca0659ac1 319 Pfam PF03640 Secreted repeat of unknown function 206 248 7.1E-15 T 06-07-2017 IPR005297 Lipoprotein repeat LK06_RS01615 3ff9886978a3615736c133aca0659ac1 319 Pfam PF03640 Secreted repeat of unknown function 267 307 1.8E-14 T 06-07-2017 IPR005297 Lipoprotein repeat LK06_RS01615 3ff9886978a3615736c133aca0659ac1 319 Pfam PF03640 Secreted repeat of unknown function 146 186 3.1E-14 T 06-07-2017 IPR005297 Lipoprotein repeat LK06_RS01615 3ff9886978a3615736c133aca0659ac1 319 Pfam PF03640 Secreted repeat of unknown function 85 127 2.1E-15 T 06-07-2017 IPR005297 Lipoprotein repeat LK06_RS02600 034911cf6182a9b461fed52dcab235ec 109 Pfam PF13751 Transposase DDE domain 1 85 1.5E-17 T 06-07-2017 IPR025668 Transposase DDE domain LK06_RS05665 5834baf69d567b6f691aa3ec98fc52ea 247 Pfam PF10127 Predicted nucleotidyltransferase 7 241 2.5E-55 T 06-07-2017 IPR018775 Nucleotidyltransferase, predicted LK06_RS18365 45cb86d1ec9447eb62d014b09645376f 89 Pfam PF13223 Protein of unknown function (DUF4031) 3 77 8.7E-31 T 06-07-2017 IPR025109 Domain of unknown function DUF4031 LK06_RS08790 42fc398b16ef913857ca5a1ab61e9c16 151 Pfam PF11253 Protein of unknown function (DUF3052) 21 145 3.2E-54 T 06-07-2017 IPR021412 Protein of unknown function DUF3052 LK06_RS29305 a4bd437f6ba8082aa8d54dcb35e99fcf 164 Gene3D G3DSA:2.30.110.10 28 159 7.9E-35 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS29305 a4bd437f6ba8082aa8d54dcb35e99fcf 164 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 32 153 7.2E-27 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related LK06_RS29305 a4bd437f6ba8082aa8d54dcb35e99fcf 164 SUPERFAMILY SSF50475 29 154 5.24E-18 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS28480 de1bda65917ba694b28678f64fe0cb50 121 Gene3D G3DSA:3.30.1380.10 38 89 4.0E-4 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 LK06_RS01045 57000b9fe69acb283cdcc3896be85506 348 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 7 154 3.3E-18 T 06-07-2017 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 LK06_RS01045 57000b9fe69acb283cdcc3896be85506 348 Gene3D G3DSA:3.40.50.2000 160 322 4.6E-9 T 06-07-2017 LK06_RS01045 57000b9fe69acb283cdcc3896be85506 348 SUPERFAMILY SSF53756 83 335 7.33E-13 T 06-07-2017 LK06_RS15770 d549386788ca71370f0a884fa1701f3d 63 SUPERFAMILY SSF57938 18 60 2.75E-5 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 LK06_RS15770 d549386788ca71370f0a884fa1701f3d 63 Gene3D G3DSA:2.10.230.10 18 61 1.2E-6 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 LK06_RS08900 20e6c18c0aa94404762fe94939e957c8 385 SUPERFAMILY SSF56601 14 361 1.93E-51 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS08900 20e6c18c0aa94404762fe94939e957c8 385 Gene3D G3DSA:3.40.710.10 11 357 2.1E-56 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS08900 20e6c18c0aa94404762fe94939e957c8 385 Pfam PF00144 Beta-lactamase 35 378 2.2E-48 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS17945 388282869ce6fbfefa240a2f3931e4ff 63 Pfam PF05122 Mobile element transfer protein 12 61 8.9E-32 T 06-07-2017 IPR007806 Mobile element transfer LK06_RS28985 90742ae2b15da29bd233080cf2ebe1dd 455 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 62 352 2.6E-31 T 06-07-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 LK06_RS28985 90742ae2b15da29bd233080cf2ebe1dd 455 SUPERFAMILY SSF51445 171 356 1.53E-50 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS28985 90742ae2b15da29bd233080cf2ebe1dd 455 SUPERFAMILY SSF51445 31 137 1.53E-50 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS28985 90742ae2b15da29bd233080cf2ebe1dd 455 Gene3D G3DSA:3.20.20.80 43 138 1.3E-50 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS28985 90742ae2b15da29bd233080cf2ebe1dd 455 Gene3D G3DSA:3.20.20.80 171 366 1.3E-50 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS16200 43cb38c09ed68aeb66488b41f88fd987 321 SUPERFAMILY SSF52540 7 210 9.87E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16200 43cb38c09ed68aeb66488b41f88fd987 321 Pfam PF00005 ABC transporter 17 160 2.5E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LK06_RS16200 43cb38c09ed68aeb66488b41f88fd987 321 Gene3D G3DSA:3.40.50.300 2 223 9.5E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS16200 43cb38c09ed68aeb66488b41f88fd987 321 SMART SM00382 25 209 1.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS05335 632aea59668355f0aed7d01d0a317287 96 Pfam PF05360 yiaA/B two helix domain 14 66 4.3E-18 T 06-07-2017 IPR008024 YiaAB two helix LK06_RS00490 cccc924e788857bb42bf55fb39dfdad0 440 Pfam PF13520 Amino acid permease 3 398 6.1E-14 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS00490 cccc924e788857bb42bf55fb39dfdad0 440 PIRSF PIRSF006060 1 436 4.3E-15 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS11125 defe39ddbca35590f9dae75f17364d11 119 Pfam PF00166 Chaperonin 10 Kd subunit 17 103 4.0E-19 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS11125 defe39ddbca35590f9dae75f17364d11 119 PRINTS PR00297 10kDa chaperonin signature 18 33 8.5E-9 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS11125 defe39ddbca35590f9dae75f17364d11 119 PRINTS PR00297 10kDa chaperonin signature 44 65 8.5E-9 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS11125 defe39ddbca35590f9dae75f17364d11 119 PRINTS PR00297 10kDa chaperonin signature 70 82 8.5E-9 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS11125 defe39ddbca35590f9dae75f17364d11 119 PRINTS PR00297 10kDa chaperonin signature 91 104 8.5E-9 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS11125 defe39ddbca35590f9dae75f17364d11 119 Gene3D G3DSA:2.30.33.40 18 103 2.4E-19 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS11125 defe39ddbca35590f9dae75f17364d11 119 SUPERFAMILY SSF50129 17 104 1.56E-17 T 06-07-2017 IPR011032 GroES-like LK06_RS11125 defe39ddbca35590f9dae75f17364d11 119 SMART SM00883 17 104 2.8E-24 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LK06_RS01850 e702b69dcf6933632fd679c99812d6b6 67 Pfam PF04149 Domain of unknown function (DUF397) 14 63 1.1E-21 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS30505 1b0706817755fa80576f1f8582d8bdef 250 Gene3D G3DSA:3.40.50.10310 5 249 1.2E-70 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 LK06_RS30505 1b0706817755fa80576f1f8582d8bdef 250 SUPERFAMILY SSF102215 5 249 2.48E-59 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 LK06_RS30505 1b0706817755fa80576f1f8582d8bdef 250 Pfam PF02633 Creatinine amidohydrolase 8 245 1.9E-62 T 06-07-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 LK06_RS19070 f7a96b938c3af9b94bdde829d78b5de0 168 PIRSF PIRSF000303 1 168 1.4E-61 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 LK06_RS19070 f7a96b938c3af9b94bdde829d78b5de0 168 PRINTS PR01011 Glutathione peroxidase family signature 129 138 1.3E-18 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 LK06_RS19070 f7a96b938c3af9b94bdde829d78b5de0 168 PRINTS PR01011 Glutathione peroxidase family signature 28 45 1.3E-18 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 LK06_RS19070 f7a96b938c3af9b94bdde829d78b5de0 168 PRINTS PR01011 Glutathione peroxidase family signature 63 79 1.3E-18 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 LK06_RS19070 f7a96b938c3af9b94bdde829d78b5de0 168 Pfam PF00255 Glutathione peroxidase 14 116 8.8E-38 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 LK06_RS19070 f7a96b938c3af9b94bdde829d78b5de0 168 Gene3D G3DSA:3.40.30.10 15 167 6.9E-61 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS19070 f7a96b938c3af9b94bdde829d78b5de0 168 ProSitePatterns PS00460 Glutathione peroxidases active site. 30 45 - T 06-07-2017 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 LK06_RS19070 f7a96b938c3af9b94bdde829d78b5de0 168 SUPERFAMILY SSF52833 17 167 2.5E-53 T 06-07-2017 IPR012336 Thioredoxin-like fold LK06_RS01555 f42a6200179cec39b8a17a17387c3c68 71 SUPERFAMILY SSF89807 3 68 1.96E-25 T 06-07-2017 IPR009923 Dodecin LK06_RS01555 f42a6200179cec39b8a17a17387c3c68 71 Gene3D G3DSA:3.30.1660.10 3 69 7.1E-37 T 06-07-2017 IPR025543 Dodecin-like LK06_RS01555 f42a6200179cec39b8a17a17387c3c68 71 Pfam PF07311 Dodecin 5 68 2.7E-29 T 06-07-2017 IPR009923 Dodecin LK06_RS02850 bfd9a47a51eff4c86956ddb0c088e7f4 81 Gene3D G3DSA:1.10.1740.10 2 59 9.3E-5 T 06-07-2017 LK06_RS02850 bfd9a47a51eff4c86956ddb0c088e7f4 81 SUPERFAMILY SSF88946 2 66 1.18E-6 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS02850 bfd9a47a51eff4c86956ddb0c088e7f4 81 Pfam PF04542 Sigma-70 region 2 2 59 2.1E-7 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 Gene3D G3DSA:3.40.50.300 341 530 1.2E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 SUPERFAMILY SSF52540 341 585 5.51E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 PRINTS PR00819 CbxX/CfqX superfamily signature 503 522 7.8E-51 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 PRINTS PR00819 CbxX/CfqX superfamily signature 340 354 7.8E-51 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 PRINTS PR00819 CbxX/CfqX superfamily signature 380 395 7.8E-51 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 PRINTS PR00819 CbxX/CfqX superfamily signature 465 477 7.8E-51 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 PRINTS PR00819 CbxX/CfqX superfamily signature 563 575 7.8E-51 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 PRINTS PR00819 CbxX/CfqX superfamily signature 486 503 7.8E-51 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 PRINTS PR00819 CbxX/CfqX superfamily signature 418 432 7.8E-51 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 PRINTS PR00819 CbxX/CfqX superfamily signature 432 451 7.8E-51 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 Gene3D G3DSA:1.25.40.10 18 52 7.9E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 Gene3D G3DSA:1.25.40.10 176 256 7.9E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 382 515 2.5E-14 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 SMART SM00382 377 518 1.5E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 SUPERFAMILY SSF48452 175 243 1.18E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 SUPERFAMILY SSF48452 334 349 1.18E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS03910 2f51d4480e260e9e25f37f7fefa6cd4a 621 SUPERFAMILY SSF48452 14 51 1.18E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS17740 0973690bb5ad7e13f8d099b010bf8e19 135 SUPERFAMILY SSF64288 3 101 1.04E-11 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS17740 0973690bb5ad7e13f8d099b010bf8e19 135 Gene3D G3DSA:3.40.1410.10 9 110 4.9E-20 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain LK06_RS17740 0973690bb5ad7e13f8d099b010bf8e19 135 Pfam PF07702 UTRA domain 42 97 1.3E-4 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LK06_RS10820 1e3b4d3852ef3cebfa54eaa8a8edea17 285 Gene3D G3DSA:1.10.3720.10 18 271 8.1E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10820 1e3b4d3852ef3cebfa54eaa8a8edea17 285 SUPERFAMILY SSF161098 18 285 2.88E-59 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS10820 1e3b4d3852ef3cebfa54eaa8a8edea17 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 272 1.3E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS17050 e6b9078d809d7027c30fceaf5b498329 82 Pfam PF11273 Protein of unknown function (DUF3073) 2 62 1.8E-21 T 06-07-2017 IPR021426 Protein of unknown function DUF3073 LK06_RS31550 2bd4bb3d123562360fb1226a52d9d5af 222 Pfam PF07884 Vitamin K epoxide reductase family 39 171 6.5E-29 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 LK06_RS31550 2bd4bb3d123562360fb1226a52d9d5af 222 SMART SM00756 34 175 2.7E-51 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 LK06_RS29215 dc3b9856658734739d781ad183ce8476 286 Gene3D G3DSA:3.30.450.20 155 252 3.8E-8 T 06-07-2017 LK06_RS29215 dc3b9856658734739d781ad183ce8476 286 SUPERFAMILY SSF55785 155 261 3.43E-9 T 06-07-2017 IPR000014 PAS domain LK06_RS30980 c8d2ab9abe62ec0aba3232be58b58305 99 Pfam PF17196 Protein of unknown function (DUF5133) 1 65 5.4E-25 T 06-07-2017 IPR033457 Protein of unknown function DUF5133 LK06_RS08630 4aaa1d78cd0f9ec70a79c8a69df2121a 130 SUPERFAMILY SSF49879 30 89 2.04E-6 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS08630 4aaa1d78cd0f9ec70a79c8a69df2121a 130 Gene3D G3DSA:2.60.200.20 23 71 2.5E-4 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS26340 f02890bf363e29c304e1a32df09a61d6 645 Pfam PF13546 DDE superfamily endonuclease 278 544 1.4E-45 T 06-07-2017 LK06_RS26340 f02890bf363e29c304e1a32df09a61d6 645 SMART SM00470 30 114 9.6E-8 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS26340 f02890bf363e29c304e1a32df09a61d6 645 Gene3D G3DSA:3.90.1530.10 49 114 1.8E-6 T 06-07-2017 LK06_RS26340 f02890bf363e29c304e1a32df09a61d6 645 Pfam PF02195 ParB-like nuclease domain 46 113 1.9E-7 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS26340 f02890bf363e29c304e1a32df09a61d6 645 SUPERFAMILY SSF110849 29 115 4.36E-9 T 06-07-2017 IPR003115 ParB/Sulfiredoxin LK06_RS31685 708f9441c29e0cfaa1b53ec2f12d9219 121 SUPERFAMILY SSF54427 13 119 3.95E-13 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS31685 708f9441c29e0cfaa1b53ec2f12d9219 121 Pfam PF14534 Domain of unknown function (DUF4440) 18 112 4.3E-9 T 06-07-2017 IPR027843 Domain of unknown function DUF4440 LK06_RS31685 708f9441c29e0cfaa1b53ec2f12d9219 121 Gene3D G3DSA:3.10.450.50 10 118 2.1E-9 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS12750 b0aba0173ce7da228988fd1721b04598 162 Gene3D G3DSA:1.10.530.10 83 160 2.4E-9 T 06-07-2017 LK06_RS12750 b0aba0173ce7da228988fd1721b04598 162 Pfam PF01464 Transglycosylase SLT domain 82 160 1.6E-8 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 LK06_RS12750 b0aba0173ce7da228988fd1721b04598 162 SUPERFAMILY SSF53955 49 162 2.46E-14 T 06-07-2017 IPR023346 Lysozyme-like domain LK06_RS10235 31789d9a09b61aacd07da2ded28ddc4f 79 Gene3D G3DSA:3.30.420.10 29 76 2.2E-4 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 Pfam PF00459 Inositol monophosphatase family 9 237 2.4E-54 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 185 206 3.4E-36 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 216 240 3.4E-36 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 3.4E-36 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 139 162 3.4E-36 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 43 63 3.4E-36 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 65 81 3.4E-36 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 SUPERFAMILY SSF56655 7 265 2.23E-73 T 06-07-2017 LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 Gene3D G3DSA:3.30.540.10 7 160 6.8E-48 T 06-07-2017 LK06_RS25445 5dfe9db529d9fc1160e5209d54f2daac 271 Gene3D G3DSA:3.40.190.80 161 265 6.5E-28 T 06-07-2017 LK06_RS27780 8199b6aff5feac71c4a6add3f81d28cd 67 SUPERFAMILY SSF56349 2 52 3.24E-7 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS27780 8199b6aff5feac71c4a6add3f81d28cd 67 Gene3D G3DSA:1.10.443.10 2 52 2.4E-7 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS26155 0de8f3cc564488e8c65b7f3843116d92 176 SUPERFAMILY SSF55729 10 161 1.08E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS26155 0de8f3cc564488e8c65b7f3843116d92 176 Gene3D G3DSA:3.40.630.30 8 161 7.4E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS26155 0de8f3cc564488e8c65b7f3843116d92 176 Pfam PF00583 Acetyltransferase (GNAT) family 54 141 4.8E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS23990 af795736bf2f2aaa9247dc1523ed9ac4 293 Pfam PF13560 Helix-turn-helix domain 13 78 6.9E-11 T 06-07-2017 LK06_RS23990 af795736bf2f2aaa9247dc1523ed9ac4 293 SMART SM00530 17 80 0.0017 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS25810 e6a03629157e69b74da65d2e96559918 104 Gene3D G3DSA:3.40.250.10 2 96 1.6E-18 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25810 e6a03629157e69b74da65d2e96559918 104 SMART SM00450 1 94 2.5E-8 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS25810 e6a03629157e69b74da65d2e96559918 104 SUPERFAMILY SSF52821 2 97 4.45E-22 T 06-07-2017 IPR001763 Rhodanese-like domain LK06_RS16505 c16b1c014b4ff4fd5fd9af51ac0c23dc 59 SUPERFAMILY SSF48498 1 57 3.69E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LK06_RS20780 e452062b1fc15886f1ae1dcf1787bbc6 200 SUPERFAMILY SSF52540 1 139 1.74E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS20780 e452062b1fc15886f1ae1dcf1787bbc6 200 Gene3D G3DSA:3.40.50.300 1 163 4.5E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS11875 e95afce32410c5b93a5a48b31fcb7dab 140 Pfam PF12005 Protein of unknown function (DUF3499) 20 136 2.6E-47 T 06-07-2017 IPR021888 Protein of unknown function DUF3499 LK06_RS08555 efe947b9e12600df75a8adac2c6c44c8 77 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 9 61 7.8E-10 T 06-07-2017 LK06_RS08555 efe947b9e12600df75a8adac2c6c44c8 77 Gene3D G3DSA:3.30.70.20 5 63 1.3E-13 T 06-07-2017 LK06_RS08555 efe947b9e12600df75a8adac2c6c44c8 77 SUPERFAMILY SSF54862 5 63 1.11E-11 T 06-07-2017 LK06_RS08555 efe947b9e12600df75a8adac2c6c44c8 77 PRINTS PR00352 3Fe-4S ferredoxin signature 20 30 6.5E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS08555 efe947b9e12600df75a8adac2c6c44c8 77 PRINTS PR00352 3Fe-4S ferredoxin signature 9 20 6.5E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS08555 efe947b9e12600df75a8adac2c6c44c8 77 PRINTS PR00352 3Fe-4S ferredoxin signature 49 61 6.5E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 LK06_RS25065 0b920b19d14ac71476cbfe7dbcfef935 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 217 1.8E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS25065 0b920b19d14ac71476cbfe7dbcfef935 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 112 5.4E-16 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 LK06_RS25065 0b920b19d14ac71476cbfe7dbcfef935 221 Gene3D G3DSA:1.10.3720.10 9 216 1.8E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS25065 0b920b19d14ac71476cbfe7dbcfef935 221 SUPERFAMILY SSF161098 10 203 2.09E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS17485 5490a37d8abd701e36868ab03350d1a4 235 SUPERFAMILY SSF48317 10 184 9.16E-32 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS17485 5490a37d8abd701e36868ab03350d1a4 235 Gene3D G3DSA:1.20.144.10 12 179 6.5E-26 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS17485 5490a37d8abd701e36868ab03350d1a4 235 Pfam PF01569 PAP2 superfamily 74 179 9.0E-16 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS17485 5490a37d8abd701e36868ab03350d1a4 235 SMART SM00014 69 180 3.4E-7 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS22615 38ddbc8dd52f33604670fc44b345dc1b 219 Pfam PF12773 Double zinc ribbon 172 216 1.5E-7 T 06-07-2017 IPR025874 Double zinc ribbon LK06_RS08880 1f1ac44c12bace7f8af8c2726137d4e3 267 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 10 231 1.4E-29 T 06-07-2017 LK06_RS09095 8003fb6202e010080571dab0362864ec 119 Gene3D G3DSA:1.10.10.60 12 49 1.5E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS09485 a1c4e0bc406b23d01bd253b9bc75ac88 246 SUPERFAMILY SSF75217 75 245 1.57E-44 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases LK06_RS09485 a1c4e0bc406b23d01bd253b9bc75ac88 246 SUPERFAMILY SSF88697 5 61 8.45E-10 T 06-07-2017 IPR015947 PUA-like domain LK06_RS09485 a1c4e0bc406b23d01bd253b9bc75ac88 246 PIRSF PIRSF015601 2 245 1.7E-47 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS09485 a1c4e0bc406b23d01bd253b9bc75ac88 246 Gene3D G3DSA:3.40.1280.10 3 246 4.9E-69 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LK06_RS09485 a1c4e0bc406b23d01bd253b9bc75ac88 246 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 11 239 1.9E-32 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS09485 a1c4e0bc406b23d01bd253b9bc75ac88 246 Pfam PF04452 RNA methyltransferase 20 238 1.4E-60 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 LK06_RS25215 fab28b5f7a47eb88ed76d9182c85b6eb 201 Pfam PF16291 Domain of unknown function (DUF4937 2 86 1.0E-28 T 06-07-2017 IPR032555 Domain of unknown function DUF4937 LK06_RS15525 d93ef262b733c6b5737f5105fed2a597 270 Gene3D G3DSA:1.10.287.110 135 173 9.4E-6 T 06-07-2017 IPR001623 DnaJ domain LK06_RS15525 d93ef262b733c6b5737f5105fed2a597 270 SUPERFAMILY SSF46565 133 173 3.4E-5 T 06-07-2017 IPR001623 DnaJ domain LK06_RS00855 c8cd59da246d70f8ee2801838770c898 127 Gene3D G3DSA:1.10.10.10 16 86 2.6E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00855 c8cd59da246d70f8ee2801838770c898 127 SUPERFAMILY SSF46785 16 123 7.53E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS00855 c8cd59da246d70f8ee2801838770c898 127 Pfam PF03965 Penicillinase repressor 16 123 7.1E-22 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 LK06_RS23700 5e2b2893bededfbd07254508b73fd296 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 LK06_RS23700 5e2b2893bededfbd07254508b73fd296 255 SUPERFAMILY SSF52096 2 253 7.76E-82 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS23700 5e2b2893bededfbd07254508b73fd296 255 Gene3D G3DSA:3.90.226.10 2 247 4.0E-85 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS23700 5e2b2893bededfbd07254508b73fd296 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 249 1.8E-67 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS31270 d7ebd6dd2a0b11e2d28b4553344bd258 96 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 21 37 3.7E-12 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC LK06_RS31270 d7ebd6dd2a0b11e2d28b4553344bd258 96 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 42 58 3.7E-12 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC LK06_RS31270 d7ebd6dd2a0b11e2d28b4553344bd258 96 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 60 72 3.7E-12 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC LK06_RS31270 d7ebd6dd2a0b11e2d28b4553344bd258 96 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 3.7E-12 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC LK06_RS31270 d7ebd6dd2a0b11e2d28b4553344bd258 96 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 06-07-2017 IPR019812 Hydrogenase assembly chaperone, conserved site LK06_RS31270 d7ebd6dd2a0b11e2d28b4553344bd258 96 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 78 1.7E-22 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC LK06_RS31270 d7ebd6dd2a0b11e2d28b4553344bd258 96 Pfam PF01455 HupF/HypC family 1 69 3.7E-25 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC LK06_RS31270 d7ebd6dd2a0b11e2d28b4553344bd258 96 SUPERFAMILY SSF159127 1 81 4.97E-23 T 06-07-2017 LK06_RS28270 83534acdd347c861c71a6c56f45bf1f8 278 PIRSF PIRSF018008 4 275 3.1E-19 T 06-07-2017 IPR008306 Uncharacterised conserved protein UCP018008 LK06_RS28270 83534acdd347c861c71a6c56f45bf1f8 278 Pfam PF04250 Protein of unknown function (DUF429) 8 245 3.7E-16 T 06-07-2017 IPR007362 Protein of unknown function DUF429 LK06_RS09260 05c6a07ac150e9f5ee01758cdb596eb9 645 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 8 201 3.1E-36 T 06-07-2017 IPR032856 Putative glycogen debranching enzyme, N-terminal LK06_RS09260 05c6a07ac150e9f5ee01758cdb596eb9 645 SUPERFAMILY SSF48208 273 639 2.17E-56 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS20565 da3eb8f6a63b2b5364c8862473bc18a4 234 Pfam PF14219 Domain of unknown function (DUF4328) 66 217 2.4E-42 T 06-07-2017 IPR025565 Domain of unknown function DUF4328 LK06_RS07055 619be409cbb5be281dae8c97cc58982d 347 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 LK06_RS07055 619be409cbb5be281dae8c97cc58982d 347 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 261 15.388 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 LK06_RS07055 619be409cbb5be281dae8c97cc58982d 347 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 11 256 2.3E-41 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 LK06_RS07055 619be409cbb5be281dae8c97cc58982d 347 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 14 255 1.1E-61 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 LK06_RS13100 f3e31090a6cc6f1f12670129461ab645 577 Pfam PF05140 ResB-like family 58 537 1.0E-128 T 06-07-2017 IPR007816 ResB-like domain LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 Gene3D G3DSA:1.25.40.10 612 806 1.8E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 Gene3D G3DSA:1.25.40.10 409 529 1.8E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 Pfam PF13191 AAA ATPase domain 14 184 1.3E-24 T 06-07-2017 LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 SUPERFAMILY SSF52540 12 200 1.02E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 SUPERFAMILY SSF48452 413 449 3.97E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 SUPERFAMILY SSF48452 613 760 3.97E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 Gene3D G3DSA:3.40.50.300 16 103 1.6E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 Gene3D G3DSA:3.40.50.300 137 185 1.6E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 SMART SM00028 414 447 75.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 SMART SM00028 611 644 19.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS28530 c7557ab12a9f2aab3652b13a0efa4c00 893 SMART SM00028 652 685 2.9 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 LK06_RS09510 abf2fe13422da55211d3048634ce5798 260 Pfam PF11296 Protein of unknown function (DUF3097) 6 258 3.4E-121 T 06-07-2017 IPR021447 Protein of unknown function DUF3097 LK06_RS07275 a0f0d572b624a058c0ef95324e6d2468 213 Pfam PF04472 Protein of unknown function (DUF552) 125 196 3.6E-27 T 06-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 LK06_RS07275 a0f0d572b624a058c0ef95324e6d2468 213 Hamap MF_01197 Cell division protein SepF [sepF]. 2 204 22.451 T 06-07-2017 IPR023052 Cell division protein SepF GO:0090529 LK06_RS17160 8ba08860ed4c214c651361e6c04ad10d 569 Pfam PF03432 Relaxase/Mobilisation nuclease domain 121 234 2.3E-4 T 06-07-2017 IPR005094 Endonuclease relaxase, MobA/VirD2 LK06_RS18585 fb740720538554576360bac3d5dd4958 330 Gene3D G3DSA:3.20.20.100 1 318 2.4E-95 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS18585 fb740720538554576360bac3d5dd4958 330 Pfam PF00248 Aldo/keto reductase family 15 317 2.6E-71 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS18585 fb740720538554576360bac3d5dd4958 330 SUPERFAMILY SSF51430 1 320 2.1E-94 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain LK06_RS27965 862e3adf832baabe41ca3426d821dc0d 218 Pfam PF02666 Phosphatidylserine decarboxylase 59 212 2.4E-30 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 LK06_RS27965 862e3adf832baabe41ca3426d821dc0d 218 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 32 217 3.1E-54 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 LK06_RS27965 862e3adf832baabe41ca3426d821dc0d 218 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 17 218 32.632 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 LK06_RS10460 a8b10e5a4bf3ec32a28372715fd21a97 316 Gene3D G3DSA:3.40.1190.20 2 312 3.0E-105 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS10460 a8b10e5a4bf3ec32a28372715fd21a97 316 SUPERFAMILY SSF53613 2 310 1.87E-77 T 06-07-2017 IPR029056 Ribokinase-like LK06_RS10460 a8b10e5a4bf3ec32a28372715fd21a97 316 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 3 309 4.8E-116 T 06-07-2017 IPR030830 5-dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 LK06_RS10460 a8b10e5a4bf3ec32a28372715fd21a97 316 Pfam PF00294 pfkB family carbohydrate kinase 7 302 9.2E-54 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB LK06_RS31490 2fc7d093e69a4e29213c93bfa54c0967 150 SUPERFAMILY SSF117916 4 87 5.89E-13 T 06-07-2017 LK06_RS31490 2fc7d093e69a4e29213c93bfa54c0967 150 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 4 149 6.5E-42 T 06-07-2017 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit LK06_RS31490 2fc7d093e69a4e29213c93bfa54c0967 150 Pfam PF01883 Domain of unknown function DUF59 4 57 1.6E-5 T 06-07-2017 IPR002744 Domain of unknown function DUF59 LK06_RS19440 62927d676b588c16634e76760d312c74 213 Pfam PF10935 Protein of unknown function (DUF2637) 11 114 1.4E-10 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 LK06_RS13920 c7bdf0893fe5822d6703cc27927748d7 373 Pfam PF03824 High-affinity nickel-transport protein 66 354 4.4E-83 T 06-07-2017 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 LK06_RS13920 c7bdf0893fe5822d6703cc27927748d7 373 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 69 349 4.2E-110 T 06-07-2017 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 LK06_RS26790 da5bfa470aa9b5f6b1363abdede11951 151 SUPERFAMILY SSF158682 20 150 3.53E-23 T 06-07-2017 IPR029024 TerB-like LK06_RS26790 da5bfa470aa9b5f6b1363abdede11951 151 Gene3D G3DSA:1.10.3680.10 21 150 1.5E-22 T 06-07-2017 IPR029024 TerB-like LK06_RS26790 da5bfa470aa9b5f6b1363abdede11951 151 Pfam PF05099 Tellurite resistance protein TerB 11 150 6.4E-32 T 06-07-2017 IPR007791 Co-chaperone DjlA, N-terminal LK06_RS26640 df8141385fe105a97b586596cd431b91 338 Pfam PF14257 Domain of unknown function (DUF4349) 34 298 3.2E-73 T 06-07-2017 IPR025645 Domain of unknown function DUF4349 LK06_RS08835 fb6d2fa2fd0034ff5cb9fa3141c403e0 275 Gene3D G3DSA:3.40.710.10 8 268 3.8E-47 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS08835 fb6d2fa2fd0034ff5cb9fa3141c403e0 275 Pfam PF00144 Beta-lactamase 14 253 1.0E-37 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS08835 fb6d2fa2fd0034ff5cb9fa3141c403e0 275 SUPERFAMILY SSF56601 8 267 1.53E-55 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS18210 6388a86c81731ae650f3c8c2c5c1a0c3 191 Pfam PF02342 TerD domain 1 187 2.0E-84 T 06-07-2017 IPR003325 TerD domain GO:0006950 LK06_RS18210 6388a86c81731ae650f3c8c2c5c1a0c3 191 Gene3D G3DSA:2.60.60.30 18 185 1.1E-73 T 06-07-2017 LK06_RS30870 bc57b81c86f278f8b37521c0d9f6f3da 361 Gene3D G3DSA:3.40.710.10 12 342 4.1E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS30870 bc57b81c86f278f8b37521c0d9f6f3da 361 SUPERFAMILY SSF56601 26 334 1.38E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS30870 bc57b81c86f278f8b37521c0d9f6f3da 361 Pfam PF00144 Beta-lactamase 19 334 8.9E-57 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS18525 efb4764e476c39dc7a990df15f841d35 1052 SUPERFAMILY SSF55874 59 150 6.29E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS18525 efb4764e476c39dc7a990df15f841d35 1052 Gene3D G3DSA:3.30.565.10 37 238 4.7E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS17635 11e277ce78d43a96cfeea6da24e2d6de 409 Gene3D G3DSA:3.90.1150.10 294 401 6.8E-10 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 LK06_RS17635 11e277ce78d43a96cfeea6da24e2d6de 409 Pfam PF00155 Aminotransferase class I and II 70 399 4.0E-29 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LK06_RS17635 11e277ce78d43a96cfeea6da24e2d6de 409 SUPERFAMILY SSF53383 51 401 5.18E-62 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase LK06_RS17635 11e277ce78d43a96cfeea6da24e2d6de 409 Gene3D G3DSA:3.40.640.10 84 293 4.4E-51 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 LK06_RS06170 54ccc3e4e2bb7eff6fa1bfa49315a088 156 Pfam PF03780 Asp23 family, cell envelope-related function 32 142 2.8E-31 T 06-07-2017 IPR005531 Alkaline shock protein Asp23 LK06_RS28965 9736852bded175ea5c3bd7c0b0721068 103 Gene3D G3DSA:1.10.443.10 6 92 3.0E-16 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS28965 9736852bded175ea5c3bd7c0b0721068 103 Pfam PF00589 Phage integrase family 8 86 1.6E-10 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LK06_RS28965 9736852bded175ea5c3bd7c0b0721068 103 SUPERFAMILY SSF56349 8 92 1.68E-15 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LK06_RS32170 99c32027df2df30031a0515372c078d2 445 Pfam PF13546 DDE superfamily endonuclease 31 242 8.5E-42 T 06-07-2017 LK06_RS32170 99c32027df2df30031a0515372c078d2 445 SUPERFAMILY SSF53098 71 379 1.44E-17 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS12575 26d54b202c8c81c5c79dc015a2ece328 925 Pfam PF05729 NACHT domain 147 315 1.9E-9 T 06-07-2017 LK06_RS12575 26d54b202c8c81c5c79dc015a2ece328 925 SUPERFAMILY SSF52540 147 329 7.5E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS12575 26d54b202c8c81c5c79dc015a2ece328 925 Gene3D G3DSA:3.40.50.300 147 281 2.5E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18775 e542f18648d3c7a8f426e80a036c03c0 128 Gene3D G3DSA:3.30.750.24 5 117 1.2E-35 T 06-07-2017 IPR002645 STAS domain LK06_RS18775 e542f18648d3c7a8f426e80a036c03c0 128 SUPERFAMILY SSF52091 6 117 1.92E-21 T 06-07-2017 IPR002645 STAS domain LK06_RS18775 e542f18648d3c7a8f426e80a036c03c0 128 Pfam PF13466 STAS domain 18 82 8.5E-14 T 06-07-2017 IPR002645 STAS domain LK06_RS18775 e542f18648d3c7a8f426e80a036c03c0 128 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 5 114 1.9E-17 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 LK06_RS10450 f859c298ff05aca41f52bc0e2ec98242 274 SUPERFAMILY SSF51182 14 252 4.56E-60 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS10450 f859c298ff05aca41f52bc0e2ec98242 274 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 21 267 5.7E-83 T 06-07-2017 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 LK06_RS10450 f859c298ff05aca41f52bc0e2ec98242 274 Gene3D G3DSA:2.60.120.10 18 121 6.3E-28 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS10450 f859c298ff05aca41f52bc0e2ec98242 274 Gene3D G3DSA:2.60.120.10 122 267 1.0E-61 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS10450 f859c298ff05aca41f52bc0e2ec98242 274 Pfam PF04962 KduI/IolB family 12 267 1.7E-88 T 06-07-2017 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 LK06_RS10450 f859c298ff05aca41f52bc0e2ec98242 274 PIRSF PIRSF036628 2 272 7.0E-101 T 06-07-2017 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 LK06_RS27225 769d89bfec2c68b4a14e9fe663c08823 423 Gene3D G3DSA:1.20.1250.20 8 192 3.7E-16 T 06-07-2017 LK06_RS27225 769d89bfec2c68b4a14e9fe663c08823 423 Gene3D G3DSA:1.20.1250.20 267 401 5.8E-10 T 06-07-2017 LK06_RS27225 769d89bfec2c68b4a14e9fe663c08823 423 Pfam PF07690 Major Facilitator Superfamily 17 361 7.1E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS27225 769d89bfec2c68b4a14e9fe663c08823 423 SUPERFAMILY SSF103473 27 403 4.19E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS03835 f8b22720dc5d6907a2972ced5c27c314 258 SUPERFAMILY SSF51695 17 251 7.85E-63 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS03835 f8b22720dc5d6907a2972ced5c27c314 258 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 23 246 7.6E-42 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 LK06_RS03835 f8b22720dc5d6907a2972ced5c27c314 258 Gene3D G3DSA:3.20.20.190 14 257 8.7E-77 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS05410 5d898a933afea6dbaceed92aa4fe9ef3 270 Pfam PF10099 Anti-sigma-K factor rskA 66 259 1.0E-34 T 06-07-2017 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 LK06_RS19425 7b67bb91a6867ba02d0da5fb71c9bb86 75 Pfam PF12728 Helix-turn-helix domain 20 68 4.0E-12 T 06-07-2017 LK06_RS19425 7b67bb91a6867ba02d0da5fb71c9bb86 75 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 20 68 4.7E-12 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 LK06_RS17610 3545805fad91f7a72112f31eb16c5e41 180 SUPERFAMILY SSF56973 71 128 1.57E-6 T 06-07-2017 LK06_RS28685 b7b5a2227226a621011c048d833a5fc0 605 Pfam PF01066 CDP-alcohol phosphatidyltransferase 196 262 5.2E-8 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS28685 b7b5a2227226a621011c048d833a5fc0 605 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 240 262 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS08055 318d539f57911276422a6f307acaefb4 507 Pfam PF09362 Domain of unknown function (DUF1996) 254 485 6.6E-31 T 06-07-2017 IPR018535 Domain of unknown function DUF1996 LK06_RS14905 05732e666d88f9fd1044ceb71882bffa 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 24 248 2.6E-26 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 LK06_RS14905 05732e666d88f9fd1044ceb71882bffa 262 Gene3D G3DSA:3.90.226.10 13 238 9.6E-48 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS14905 05732e666d88f9fd1044ceb71882bffa 262 SUPERFAMILY SSF52096 14 238 2.38E-47 T 06-07-2017 IPR029045 ClpP/crotonase-like domain LK06_RS19430 ea192b878e2bfc2594d29229032cabf4 215 Pfam PF06114 Domain of unknown function (DUF955) 70 175 6.9E-19 T 06-07-2017 IPR010359 HTH domain, IrrE-type LK06_RS23375 6883f17a0634f4b124fb50cde6519cd6 906 Gene3D G3DSA:3.40.50.300 103 215 9.0E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23375 6883f17a0634f4b124fb50cde6519cd6 906 SUPERFAMILY SSF52540 100 260 7.71E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS08845 bb4028176c748a6e79ea9485870e26f6 401 Pfam PF13556 PucR C-terminal helix-turn-helix domain 333 390 8.9E-20 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS08690 71be89cd4b7ec5ad007de746bc89624c 656 Pfam PF13454 FAD-NAD(P)-binding 37 201 2.5E-43 T 06-07-2017 LK06_RS08690 71be89cd4b7ec5ad007de746bc89624c 656 Gene3D G3DSA:3.50.50.60 32 187 1.8E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS10885 cd31b9ffa0448cf882b38294c0f88644 445 Gene3D G3DSA:3.40.50.300 17 229 3.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10885 cd31b9ffa0448cf882b38294c0f88644 445 SUPERFAMILY SSF52540 21 396 5.45E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS10885 cd31b9ffa0448cf882b38294c0f88644 445 Pfam PF13245 Part of AAA domain 25 89 3.6E-10 T 06-07-2017 LK06_RS00360 f24b87b41536e6464051173eb4caedf6 356 Gene3D G3DSA:3.40.50.1100 95 353 3.9E-55 T 06-07-2017 LK06_RS00360 f24b87b41536e6464051173eb4caedf6 356 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 52 318 6.5E-64 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS00360 f24b87b41536e6464051173eb4caedf6 356 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 65 78 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 LK06_RS00360 f24b87b41536e6464051173eb4caedf6 356 SUPERFAMILY SSF53686 57 319 4.85E-66 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS06595 ac1191dc85a253b447dbfb45617ada08 760 Pfam PF02687 FtsX-like permease family 632 750 3.3E-11 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS06595 ac1191dc85a253b447dbfb45617ada08 760 Pfam PF02687 FtsX-like permease family 247 364 4.4E-11 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS06265 8e985e8589ea06ee5857fb1b1b25017d 242 Pfam PF02535 ZIP Zinc transporter 89 236 1.8E-11 T 06-07-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 LK06_RS04880 4c6509b7f89ee0bf6805bd71b9eb9a37 229 SUPERFAMILY SSF52317 32 223 2.14E-37 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS04880 4c6509b7f89ee0bf6805bd71b9eb9a37 229 Gene3D G3DSA:3.40.50.880 4 213 1.0E-39 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like LK06_RS04880 4c6509b7f89ee0bf6805bd71b9eb9a37 229 Pfam PF07722 Peptidase C26 5 212 2.0E-64 T 06-07-2017 IPR011697 Peptidase C26 GO:0006541|GO:0016787 LK06_RS00065 f08b302f5bafc6d7e5faed110027a211 118 Gene3D G3DSA:3.90.50.10 9 102 8.5E-7 T 06-07-2017 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 LK06_RS00065 f08b302f5bafc6d7e5faed110027a211 118 Pfam PF05239 PRC-barrel domain 7 75 1.6E-5 T 06-07-2017 IPR027275 PRC-barrel domain LK06_RS00065 f08b302f5bafc6d7e5faed110027a211 118 SUPERFAMILY SSF50346 6 105 7.06E-21 T 06-07-2017 IPR011033 PRC-barrel-like LK06_RS05950 cca1795567e30b01107947fcd3c8ed09 172 Gene3D G3DSA:3.40.50.1240 4 171 7.0E-52 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS05950 cca1795567e30b01107947fcd3c8ed09 172 SUPERFAMILY SSF53254 6 154 3.43E-22 T 06-07-2017 IPR029033 Histidine phosphatase superfamily LK06_RS05950 cca1795567e30b01107947fcd3c8ed09 172 SMART SM00855 8 119 1.9E-5 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS05950 cca1795567e30b01107947fcd3c8ed09 172 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 100 3.2E-10 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 LK06_RS05990 b257953944529de93bfa838539a5fb95 508 SUPERFAMILY SSF111283 12 498 1.09E-96 T 06-07-2017 LK06_RS05990 b257953944529de93bfa838539a5fb95 508 Pfam PF01523 Putative modulator of DNA gyrase 32 347 4.8E-50 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 LK06_RS05785 83f022dc8fc3d5797831a52e2c3c6de2 351 SUPERFAMILY SSF81345 22 342 7.19E-71 T 06-07-2017 IPR029022 ABC transporter, BtuC-like LK06_RS05785 83f022dc8fc3d5797831a52e2c3c6de2 351 Pfam PF01032 FecCD transport family 41 343 1.6E-82 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 LK06_RS05785 83f022dc8fc3d5797831a52e2c3c6de2 351 Gene3D G3DSA:1.10.3470.10 26 347 5.8E-92 T 06-07-2017 IPR029022 ABC transporter, BtuC-like LK06_RS03230 3ff882c945e920010d32fc18470b79ed 77 SUPERFAMILY SSF46689 7 60 4.93E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS01295 1bd24dc2cb7a0547903ea0ccdee13c2f 251 Pfam PF02754 Cysteine-rich domain 138 222 8.2E-18 T 06-07-2017 IPR004017 Cysteine-rich domain LK06_RS01295 1bd24dc2cb7a0547903ea0ccdee13c2f 251 Pfam PF02754 Cysteine-rich domain 3 83 3.1E-14 T 06-07-2017 IPR004017 Cysteine-rich domain LK06_RS12720 47f872b28a5f66f8f743e58262b9138c 341 Pfam PF00892 EamA-like transporter family 157 287 2.3E-7 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS12720 47f872b28a5f66f8f743e58262b9138c 341 Pfam PF00892 EamA-like transporter family 11 147 2.9E-10 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS12720 47f872b28a5f66f8f743e58262b9138c 341 TIGRFAM TIGR00688 rarD: protein RarD 14 262 5.1E-64 T 06-07-2017 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 LK06_RS12720 47f872b28a5f66f8f743e58262b9138c 341 SUPERFAMILY SSF103481 52 149 7.98E-12 T 06-07-2017 LK06_RS12720 47f872b28a5f66f8f743e58262b9138c 341 SUPERFAMILY SSF103481 197 287 4.84E-10 T 06-07-2017 LK06_RS14700 53cb1c56a44d5adf10804866356f38c1 176 Pfam PF10722 Putative bacterial sensory transduction regulator 30 155 1.3E-16 T 06-07-2017 IPR019660 Putative sensory transduction regulator YbjN LK06_RS10380 7c4e19297b7003eb73405e257d620d42 429 SUPERFAMILY SSF51445 127 350 5.95E-34 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily LK06_RS10380 7c4e19297b7003eb73405e257d620d42 429 Gene3D G3DSA:3.20.20.80 90 369 1.3E-42 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 LK06_RS10380 7c4e19297b7003eb73405e257d620d42 429 Pfam PF02156 Glycosyl hydrolase family 26 222 309 4.0E-8 T 06-07-2017 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 LK06_RS23265 98c1cf26b95dea8c59c70fdc83510e07 444 Pfam PF00953 Glycosyl transferase family 4 83 242 2.7E-35 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 LK06_RS01390 4e1b17bdf535f39274a8fb02d830369d 187 Gene3D G3DSA:3.40.630.30 3 186 1.1E-46 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS01390 4e1b17bdf535f39274a8fb02d830369d 187 SUPERFAMILY SSF55729 3 157 4.99E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS01390 4e1b17bdf535f39274a8fb02d830369d 187 Pfam PF13302 Acetyltransferase (GNAT) domain 9 153 6.8E-30 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS05030 039457c66b27baba5d3966f11937a641 497 Pfam PF03136 Pup-ligase protein 1 451 3.6E-190 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 LK06_RS05030 039457c66b27baba5d3966f11937a641 497 PIRSF PIRSF018077 4 494 3.1E-218 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 LK06_RS05030 039457c66b27baba5d3966f11937a641 497 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 1 484 1.2E-244 T 06-07-2017 IPR022366 Pup deamidase GO:0008233|GO:0016811 LK06_RS03510 7b09e2bcf75156e016ad4e19e8fa85e7 148 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 78 8.7E-20 T 06-07-2017 IPR025161 Putative transposase IS4/IS5 family LK06_RS03510 7b09e2bcf75156e016ad4e19e8fa85e7 148 Pfam PF01609 Transposase DDE domain 97 147 3.8E-5 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS14045 07774ce4d64f7d457a82f07bfcdf7573 196 Pfam PF00482 Type II secretion system (T2SS), protein F 59 181 2.6E-12 T 06-07-2017 IPR018076 Type II secretion system F domain LK06_RS07365 aad2b7ef9b46623ce254a23617523982 127 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 6.3E-29 T 06-07-2017 IPR021401 Protein of unknown function DUF3040 LK06_RS11965 fe791e48c1130667da857cd9142d497d 441 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 198 353 8.0E-40 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS11965 fe791e48c1130667da857cd9142d497d 441 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 198 353 1.8E-44 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS28635 5cf42408b2c6202ad6be55fcdc6797a5 488 ProSitePatterns PS00218 Amino acid permeases signature. 62 92 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 LK06_RS28635 5cf42408b2c6202ad6be55fcdc6797a5 488 PIRSF PIRSF006060 19 486 3.4E-56 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS28635 5cf42408b2c6202ad6be55fcdc6797a5 488 Pfam PF00324 Amino acid permease 37 473 7.5E-101 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 LK06_RS22900 de377b1c4d6f144123045146da7c5531 158 Pfam PF14124 Domain of unknown function (DUF4291) 10 146 1.2E-52 T 06-07-2017 IPR025633 Protein of unknown function DUF4291 LK06_RS19215 a33f17a4041a8e3188e3e6f1e16a9f2f 555 Gene3D G3DSA:1.10.10.60 316 345 2.4E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS19215 a33f17a4041a8e3188e3e6f1e16a9f2f 555 Pfam PF01610 Transposase 434 550 7.7E-8 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain LK06_RS19215 a33f17a4041a8e3188e3e6f1e16a9f2f 555 Pfam PF01610 Transposase 161 256 1.8E-17 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain LK06_RS09700 a86677ca48a95cf2e2061d14a817e72f 156 Gene3D G3DSA:3.90.79.10 5 149 4.8E-37 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS09700 a86677ca48a95cf2e2061d14a817e72f 156 Pfam PF00293 NUDIX domain 20 137 5.8E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 LK06_RS09700 a86677ca48a95cf2e2061d14a817e72f 156 SUPERFAMILY SSF55811 5 150 1.9E-35 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 LK06_RS17520 040d76d59c1aeae57982ca78cc08ded3 332 Pfam PF01384 Phosphate transporter family 20 166 1.3E-39 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 LK06_RS17520 040d76d59c1aeae57982ca78cc08ded3 332 Pfam PF01384 Phosphate transporter family 164 320 7.3E-46 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 LK06_RS08320 451760a5b29934be00b0e6e773b556c3 348 SUPERFAMILY SSF56601 11 324 5.32E-74 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS08320 451760a5b29934be00b0e6e773b556c3 348 Pfam PF00144 Beta-lactamase 11 336 1.7E-61 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS08320 451760a5b29934be00b0e6e773b556c3 348 Gene3D G3DSA:3.40.710.10 9 327 7.4E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS15640 1d8b93f70a49f771ea1d78b74de3c8fe 233 ProDom PD190647 REGULATORY RESISTANCE TRANSCRIPTION TRANSCRIPTIONAL ANTIBIOTIC DNA-BINDING ACTIVATOR REGULATION ORF699 NOSIHEPTIDE 1 232 9.0E-82 T 06-07-2017 LK06_RS22185 49c949bf713e971f8dd8efb3c5c06801 514 Pfam PF08386 TAP-like protein 409 513 5.6E-34 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal LK06_RS22185 49c949bf713e971f8dd8efb3c5c06801 514 SUPERFAMILY SSF53474 193 486 1.18E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22185 49c949bf713e971f8dd8efb3c5c06801 514 SUPERFAMILY SSF53474 105 151 1.18E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22185 49c949bf713e971f8dd8efb3c5c06801 514 Gene3D G3DSA:3.40.50.1820 197 321 7.8E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22185 49c949bf713e971f8dd8efb3c5c06801 514 Gene3D G3DSA:3.40.50.1820 68 153 7.8E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS22185 49c949bf713e971f8dd8efb3c5c06801 514 Gene3D G3DSA:3.40.50.1820 380 501 7.8E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS13080 590ae5e76ea40f1c74ff800e1b3428a7 149 SUPERFAMILY SSF53927 6 145 5.88E-35 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 LK06_RS13080 590ae5e76ea40f1c74ff800e1b3428a7 149 Gene3D G3DSA:3.40.140.10 3 136 4.1E-33 T 06-07-2017 LK06_RS13080 590ae5e76ea40f1c74ff800e1b3428a7 149 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 101 2.0E-17 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 LK06_RS21145 e4bd88fe9e471fb6f7e548fd38e32570 437 PIRSF PIRSF033563 19 431 5.4E-101 T 06-07-2017 IPR008323 Uncharacterised conserved protein UCP033563 LK06_RS21145 e4bd88fe9e471fb6f7e548fd38e32570 437 Pfam PF06245 Protein of unknown function (DUF1015) 22 427 2.5E-104 T 06-07-2017 IPR008323 Uncharacterised conserved protein UCP033563 LK06_RS02665 5986118a6fbb9593dc4388ea324db69d 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 3.6E-7 T 06-07-2017 LK06_RS02665 5986118a6fbb9593dc4388ea324db69d 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 3.6E-7 T 06-07-2017 LK06_RS02665 5986118a6fbb9593dc4388ea324db69d 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 3.6E-7 T 06-07-2017 LK06_RS02665 5986118a6fbb9593dc4388ea324db69d 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 388 403 3.6E-7 T 06-07-2017 LK06_RS02665 5986118a6fbb9593dc4388ea324db69d 534 SUPERFAMILY SSF51905 6 242 1.09E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02665 5986118a6fbb9593dc4388ea324db69d 534 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 11 210 1.6E-18 T 06-07-2017 LK06_RS02665 5986118a6fbb9593dc4388ea324db69d 534 Gene3D G3DSA:3.50.50.60 359 529 1.0E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02665 5986118a6fbb9593dc4388ea324db69d 534 Gene3D G3DSA:3.50.50.60 5 247 8.4E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02665 5986118a6fbb9593dc4388ea324db69d 534 SUPERFAMILY SSF51905 318 532 6.47E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS03565 a1e165635734930c71b20db07b8eee9e 505 PIRSF PIRSF012666 1 498 1.3E-222 T 06-07-2017 IPR016602 Uncharacterised conserved protein UCP012666 LK06_RS03565 a1e165635734930c71b20db07b8eee9e 505 SUPERFAMILY SSF55931 37 462 5.0E-48 T 06-07-2017 LK06_RS11450 a22922dd62e4a0f1188bdeda69b72841 248 Pfam PF13490 Putative zinc-finger 8 34 3.6E-7 T 06-07-2017 IPR027383 Putative zinc-finger LK06_RS17200 5289b7c3f1fa74db212ad305622d463d 317 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 6 312 8.1E-130 T 06-07-2017 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family LK06_RS17200 5289b7c3f1fa74db212ad305622d463d 317 SUPERFAMILY SSF56059 135 314 6.86E-23 T 06-07-2017 LK06_RS17200 5289b7c3f1fa74db212ad305622d463d 317 Gene3D G3DSA:3.30.1490.20 144 170 1.6E-5 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 LK06_RS16535 36deaf256f56af77ca9e3eb930316984 48 SUPERFAMILY SSF46689 5 48 1.27E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS16535 36deaf256f56af77ca9e3eb930316984 48 Gene3D G3DSA:1.10.10.60 9 48 3.1E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS18395 638a72436507cd110ac164753971c1b1 122 Gene3D G3DSA:1.10.101.10 41 110 3.3E-20 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18395 638a72436507cd110ac164753971c1b1 122 Pfam PF01471 Putative peptidoglycan binding domain 52 106 1.8E-10 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18395 638a72436507cd110ac164753971c1b1 122 SUPERFAMILY SSF47090 42 110 2.88E-16 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS23175 b805be14a0c89acd67b86c1780ea91c4 126 Pfam PF01609 Transposase DDE domain 18 82 6.5E-9 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS20470 2a242ff53da62616f23d5bd399225db8 276 Gene3D G3DSA:1.10.260.40 16 70 7.3E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS20470 2a242ff53da62616f23d5bd399225db8 276 SMART SM00530 20 75 6.1E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS20470 2a242ff53da62616f23d5bd399225db8 276 Pfam PF13560 Helix-turn-helix domain 16 71 1.4E-16 T 06-07-2017 LK06_RS20470 2a242ff53da62616f23d5bd399225db8 276 SUPERFAMILY SSF47413 16 69 1.56E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS12025 af7822cf9bc44453136c32029470b703 170 Pfam PF04138 GtrA-like protein 17 137 4.0E-24 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 LK06_RS12115 94c9381340167acac86b880dcbaa8139 124 Gene3D G3DSA:3.30.450.30 8 123 6.4E-4 T 06-07-2017 LK06_RS07745 4f4d9b3505c5eff881aa8c149cd98afa 339 Pfam PF13489 Methyltransferase domain 120 272 9.7E-21 T 06-07-2017 LK06_RS07745 4f4d9b3505c5eff881aa8c149cd98afa 339 Gene3D G3DSA:3.40.50.150 108 274 1.3E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07745 4f4d9b3505c5eff881aa8c149cd98afa 339 SUPERFAMILY SSF53335 105 299 1.04E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS18080 61f67c959ea730879e4a6c0da4310e77 182 Pfam PF05598 Transposase domain (DUF772) 45 119 4.7E-18 T 06-07-2017 IPR008490 Transposase InsH, N-terminal LK06_RS28525 5aa1dc8d344cba896269db2b9aaa20a4 346 Pfam PF10708 Protein of unknown function (DUF2510) 7 43 5.4E-10 T 06-07-2017 IPR018929 Domain of unknown function DUF2510 LK06_RS16755 cdc6c1d46d8f3eccb895809c697fe634 194 Pfam PF14016 Protein of unknown function (DUF4232) 52 164 9.9E-11 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 LK06_RS20145 769c4d9422824132a8a3e94e939205c1 109 Pfam PF02467 Transcription factor WhiB 17 87 6.2E-25 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS20145 769c4d9422824132a8a3e94e939205c1 109 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 95 19.571 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS11955 6e78e68146508c9452870405cdbf6b45 460 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 344 430 3.0E-13 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain LK06_RS11955 6e78e68146508c9452870405cdbf6b45 460 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 79 233 1.6E-46 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS11955 6e78e68146508c9452870405cdbf6b45 460 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 79 233 1.1E-44 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS18180 53f498c2077e8ad73c4479428f5ef101 215 Pfam PF13599 Pentapeptide repeats (9 copies) 115 172 1.6E-8 T 06-07-2017 IPR001646 Pentapeptide repeat LK06_RS18180 53f498c2077e8ad73c4479428f5ef101 215 SUPERFAMILY SSF141571 32 205 3.14E-33 T 06-07-2017 LK06_RS09670 9a12970b99a49bc611cb440e4026cb03 142 Pfam PF13358 DDE superfamily endonuclease 24 106 5.3E-18 T 06-07-2017 LK06_RS03185 0a280d527ef9390d08e78f3746b8668c 149 Pfam PF11236 Protein of unknown function (DUF3037) 31 148 1.6E-41 T 06-07-2017 IPR021398 Protein of unknown function DUF3037 LK06_RS02360 066bf640066470e9e2d8e29b8bb60a05 74 Pfam PF04149 Domain of unknown function (DUF397) 18 74 2.5E-19 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS18555 c5a39294c4ad258e2a03395b929e2019 483 Pfam PF00860 Permease family 42 439 1.0E-26 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS28070 ec02e6c7fbef6a112b094b4937ef7b05 115 Gene3D G3DSA:3.10.180.10 3 109 1.2E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS28070 ec02e6c7fbef6a112b094b4937ef7b05 115 SUPERFAMILY SSF54593 9 109 1.75E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS30610 5448eb0ddfc31f5dea8ea62fb5925c69 81 Pfam PF04149 Domain of unknown function (DUF397) 25 74 5.9E-10 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS21700 9f4038912d60bb8a3e953e75690d4358 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 85 1.8E-13 T 06-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family LK06_RS21700 9f4038912d60bb8a3e953e75690d4358 87 SUPERFAMILY SSF143011 4 83 1.44E-19 T 06-07-2017 LK06_RS02590 99b40efc3962dc2f7d27eb8faf2c4c3f 437 Gene3D G3DSA:3.50.50.60 310 349 5.1E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02590 99b40efc3962dc2f7d27eb8faf2c4c3f 437 Gene3D G3DSA:3.50.50.60 104 195 5.1E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02590 99b40efc3962dc2f7d27eb8faf2c4c3f 437 Gene3D G3DSA:3.50.50.60 6 70 5.1E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02590 99b40efc3962dc2f7d27eb8faf2c4c3f 437 SUPERFAMILY SSF51905 306 373 4.54E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS02590 99b40efc3962dc2f7d27eb8faf2c4c3f 437 SUPERFAMILY SSF51905 7 199 4.54E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS23470 be19ac5e8584c1d1eaee620fb3f8cdf7 98 Gene3D G3DSA:3.30.70.930 1 92 2.7E-34 T 06-07-2017 IPR029756 MTH1187/YkoF-like LK06_RS23470 be19ac5e8584c1d1eaee620fb3f8cdf7 98 SUPERFAMILY SSF89957 1 95 3.27E-29 T 06-07-2017 IPR029756 MTH1187/YkoF-like LK06_RS23470 be19ac5e8584c1d1eaee620fb3f8cdf7 98 Pfam PF01910 Thiamine-binding protein 3 92 1.3E-29 T 06-07-2017 IPR002767 Thiamine-binding protein LK06_RS23470 be19ac5e8584c1d1eaee620fb3f8cdf7 98 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 94 2.1E-18 T 06-07-2017 IPR002767 Thiamine-binding protein LK06_RS13870 2e08626a3cf1f8981276749cc8ade9c2 274 Pfam PF13560 Helix-turn-helix domain 3 65 5.2E-14 T 06-07-2017 LK06_RS13870 2e08626a3cf1f8981276749cc8ade9c2 274 Gene3D G3DSA:1.10.260.40 2 57 2.3E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS13870 2e08626a3cf1f8981276749cc8ade9c2 274 SUPERFAMILY SSF47413 1 58 1.01E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 LK06_RS13870 2e08626a3cf1f8981276749cc8ade9c2 274 SMART SM00530 6 61 9.6E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LK06_RS26560 87b9657dbc3a3ff76218023285b28f62 434 Pfam PF02653 Branched-chain amino acid transport system / permease component 88 416 2.3E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 LK06_RS14070 c363d3dfd9f35b7518a5e5c684af7e6e 274 Pfam PF02661 Fic/DOC family 113 202 5.0E-5 T 06-07-2017 IPR003812 Fido domain LK06_RS14070 c363d3dfd9f35b7518a5e5c684af7e6e 274 SUPERFAMILY SSF140931 106 251 1.44E-5 T 06-07-2017 IPR003812 Fido domain LK06_RS14070 c363d3dfd9f35b7518a5e5c684af7e6e 274 Gene3D G3DSA:1.10.3290.10 42 239 3.4E-9 T 06-07-2017 IPR003812 Fido domain LK06_RS10495 239dc693047cccb05d00ad962217e0d2 487 Gene3D G3DSA:3.40.50.620 176 412 1.3E-10 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS10495 239dc693047cccb05d00ad962217e0d2 487 SUPERFAMILY SSF52402 360 452 1.68E-15 T 06-07-2017 LK06_RS10495 239dc693047cccb05d00ad962217e0d2 487 SUPERFAMILY SSF52402 176 318 1.68E-15 T 06-07-2017 LK06_RS10495 239dc693047cccb05d00ad962217e0d2 487 Pfam PF00733 Asparagine synthase 177 318 7.9E-5 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 LK06_RS18560 71f3a5031d67c1b246ed9457bfeeed74 60 SUPERFAMILY SSF47598 4 39 4.45E-7 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 LK06_RS18560 71f3a5031d67c1b246ed9457bfeeed74 60 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 29 2.2E-4 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 LK06_RS13585 ec72307fe62fa58521fd710805ed95a3 574 Gene3D G3DSA:1.10.1740.10 39 129 7.8E-4 T 06-07-2017 LK06_RS13585 ec72307fe62fa58521fd710805ed95a3 574 Gene3D G3DSA:2.60.40.360 417 490 6.4E-4 T 06-07-2017 IPR008962 PapD-like LK06_RS32290 786703ba11c9857b65b6800d675ad145 333 Gene3D G3DSA:1.20.144.10 125 247 3.3E-5 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS32290 786703ba11c9857b65b6800d675ad145 333 SUPERFAMILY SSF48317 131 252 1.24E-8 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LK06_RS31220 af96150b68c59da9e1ac643bf8e01e61 220 Pfam PF12138 Spherulation-specific family 4 3 180 1.3E-31 T 06-07-2017 IPR021986 Spherulation-specific family 4 LK06_RS00245 2b11a2fd1b16ca08ef1051d847fdd57d 197 Pfam PF01813 ATP synthase subunit D 1 180 1.3E-25 T 06-07-2017 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 LK06_RS21735 64e84d84500b5d639ecd3424674263b8 324 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 44 262 1.9E-7 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region LK06_RS21735 64e84d84500b5d639ecd3424674263b8 324 SUPERFAMILY SSF63829 22 302 9.81E-31 T 06-07-2017 LK06_RS21735 64e84d84500b5d639ecd3424674263b8 324 Gene3D G3DSA:2.120.10.30 38 297 1.5E-25 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like LK06_RS08495 6c6ff1215b8f3258683354b5da28985f 356 Gene3D G3DSA:1.50.10.20 20 220 1.4E-17 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS08495 6c6ff1215b8f3258683354b5da28985f 356 Gene3D G3DSA:1.50.10.20 264 335 1.4E-17 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LK06_RS08495 6c6ff1215b8f3258683354b5da28985f 356 SUPERFAMILY SSF48208 37 333 9.41E-38 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS22790 6ba56d01fab69f265b4c46bd3a737c50 330 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 12 255 9.5E-78 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain LK06_RS27425 dc85006649c761f5441f0388dd72bd6b 140 Gene3D G3DSA:3.10.129.10 2 132 1.1E-33 T 06-07-2017 IPR029069 HotDog domain LK06_RS27425 dc85006649c761f5441f0388dd72bd6b 140 Pfam PF13279 Thioesterase-like superfamily 14 119 1.9E-15 T 06-07-2017 LK06_RS27425 dc85006649c761f5441f0388dd72bd6b 140 SUPERFAMILY SSF54637 3 133 1.75E-35 T 06-07-2017 IPR029069 HotDog domain LK06_RS26710 064016d7d9a4939126134533a3a3c968 287 SUPERFAMILY SSF53597 68 286 8.67E-36 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 LK06_RS26710 064016d7d9a4939126134533a3a3c968 287 Pfam PF01872 RibD C-terminal domain 70 263 4.5E-27 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 LK06_RS26710 064016d7d9a4939126134533a3a3c968 287 Gene3D G3DSA:3.40.430.10 64 286 4.4E-57 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 LK06_RS24080 c79aae09278a81cde055653c281140d7 193 Pfam PF03029 Conserved hypothetical ATP binding protein 21 188 3.6E-28 T 06-07-2017 IPR004130 GPN-loop GTPase LK06_RS24080 c79aae09278a81cde055653c281140d7 193 Gene3D G3DSA:3.40.50.300 11 186 2.5E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24080 c79aae09278a81cde055653c281140d7 193 SUPERFAMILY SSF52540 16 190 7.98E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09100 881c335111ed0d583d25d5e69539b6c4 365 Pfam PF13481 AAA domain 57 201 4.2E-9 T 06-07-2017 LK06_RS09100 881c335111ed0d583d25d5e69539b6c4 365 SUPERFAMILY SSF52540 57 207 2.04E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09100 881c335111ed0d583d25d5e69539b6c4 365 Gene3D G3DSA:3.40.50.300 57 233 1.6E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS32265 000f59e0f16aff5b8cd5c1feaaf410fc 67 Pfam PF12728 Helix-turn-helix domain 12 61 2.2E-8 T 06-07-2017 LK06_RS04975 c39cc1f58f0f1eefc648e06478672b86 346 Pfam PF13280 WYL domain 154 321 6.9E-32 T 06-07-2017 IPR026881 WYL domain LK06_RS04975 c39cc1f58f0f1eefc648e06478672b86 346 PIRSF PIRSF016838 8 328 2.9E-85 T 06-07-2017 IPR028349 Protein PafC LK06_RS00625 c648abab1b2fba3dbd0a87837b3df9aa 547 Pfam PF04476 Putative methanogenic enzyme for methanofuran 11 159 2.9E-7 T 06-07-2017 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5423|MetaCyc: PWY-7410 LK06_RS07565 92eb4502901eb842e27e02b56adb9ab1 411 PIRSF PIRSF010361 1 409 4.6E-88 T 06-07-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane LK06_RS07565 92eb4502901eb842e27e02b56adb9ab1 411 Pfam PF09594 Protein of unknown function (DUF2029) 66 309 3.7E-14 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 LK06_RS10210 25d1ddfd7f8fb310d480fa80c76dc06f 452 Pfam PF05506 Domain of unknown function (DUF756) 315 377 2.6E-8 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 LK06_RS10210 25d1ddfd7f8fb310d480fa80c76dc06f 452 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 107 154 1.8E-17 T 06-07-2017 IPR023849 Uncharacterised domain CHP03934, TQXA LK06_RS25050 be604880871c579751cfb63cc74ddbc4 407 Gene3D G3DSA:1.20.1250.20 22 203 1.6E-9 T 06-07-2017 LK06_RS25050 be604880871c579751cfb63cc74ddbc4 407 Gene3D G3DSA:1.20.1250.20 252 396 1.1E-8 T 06-07-2017 LK06_RS25050 be604880871c579751cfb63cc74ddbc4 407 SUPERFAMILY SSF103473 22 399 1.2E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS26940 9f0f16489eb44fdf7ef5d6956d8dec78 369 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 54 349 2.1E-57 T 06-07-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 LK06_RS26940 9f0f16489eb44fdf7ef5d6956d8dec78 369 SUPERFAMILY SSF53850 53 284 5.44E-36 T 06-07-2017 LK06_RS26940 9f0f16489eb44fdf7ef5d6956d8dec78 369 Gene3D G3DSA:3.40.190.10 138 270 2.2E-15 T 06-07-2017 LK06_RS26940 9f0f16489eb44fdf7ef5d6956d8dec78 369 Pfam PF13379 NMT1-like family 53 288 9.7E-25 T 06-07-2017 LK06_RS16020 2f14471ab01ac2e1016c03169142b464 461 Gene3D G3DSA:3.40.710.10 25 340 3.1E-74 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS16020 2f14471ab01ac2e1016c03169142b464 461 Pfam PF00144 Beta-lactamase 24 338 3.9E-62 T 06-07-2017 IPR001466 Beta-lactamase-related LK06_RS16020 2f14471ab01ac2e1016c03169142b464 461 SUPERFAMILY SSF56601 12 335 1.06E-71 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like LK06_RS22970 680cf4f827e0457d79e0aa0f44653807 116 Gene3D G3DSA:2.140.10.10 22 95 7.7E-5 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain LK06_RS26995 3f1881961237b4cc7031136d4228a51c 386 Pfam PF03631 Virulence factor BrkB 45 299 2.6E-46 T 06-07-2017 IPR017039 Virulence factor BrkB LK06_RS02340 f3a55f5bc6833cfe6c61e193f5c4cfd9 157 Pfam PF00877 NlpC/P60 family 56 145 7.8E-25 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS02340 f3a55f5bc6833cfe6c61e193f5c4cfd9 157 SUPERFAMILY SSF54001 42 153 1.28E-36 T 06-07-2017 LK06_RS02340 f3a55f5bc6833cfe6c61e193f5c4cfd9 157 Gene3D G3DSA:3.90.1720.10 38 154 2.1E-39 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain LK06_RS04445 f92cd61b4f23bf106af6568cfa303ba4 283 Pfam PF13814 Replication-relaxation 21 231 2.9E-42 T 06-07-2017 IPR025855 Plasmid replication-relaxation LK06_RS04915 ceb4a3d7ef7216af5f685a00350bdcfb 312 Pfam PF06189 5'-nucleotidase 40 307 8.2E-107 T 06-07-2017 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|Reactome: R-HSA-74259 LK06_RS27550 66e47702cc3ceeb6acddc829fd3cbb6e 269 Pfam PF01987 Mitochondrial biogenesis AIM24 6 238 4.0E-52 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS27550 66e47702cc3ceeb6acddc829fd3cbb6e 269 Gene3D G3DSA:3.60.160.10 3 261 1.9E-71 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 LK06_RS27550 66e47702cc3ceeb6acddc829fd3cbb6e 269 SUPERFAMILY SSF51219 4 251 7.06E-49 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain LK06_RS27705 0bc7fcd072101308021f0c8df26d1935 302 SUPERFAMILY SSF51735 234 256 1.47E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27705 0bc7fcd072101308021f0c8df26d1935 302 SUPERFAMILY SSF51735 4 206 1.47E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27705 0bc7fcd072101308021f0c8df26d1935 302 Gene3D G3DSA:3.40.50.720 7 256 9.3E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain LK06_RS27705 0bc7fcd072101308021f0c8df26d1935 302 Pfam PF00106 short chain dehydrogenase 8 200 7.9E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27705 0bc7fcd072101308021f0c8df26d1935 302 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 197 0.0098 T 06-07-2017 LK06_RS27705 0bc7fcd072101308021f0c8df26d1935 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27705 0bc7fcd072101308021f0c8df26d1935 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27705 0bc7fcd072101308021f0c8df26d1935 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS27705 0bc7fcd072101308021f0c8df26d1935 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR LK06_RS11780 cd40adfccb3a20c5f04f938c3d9275ad 447 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 287 364 3.0E-9 T 06-07-2017 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain LK06_RS19235 ff1d877a258be578ccf83ae9400be630 61 Gene3D G3DSA:3.50.50.60 14 55 1.9E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LK06_RS24075 51d6dfaf2be4f1795516a573bc223e4b 65 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 4 63 4.8E-17 T 06-07-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit LK06_RS00320 9f71fd8d675c8a2ffd90a613137e055d 464 Pfam PF00374 Nickel-dependent hydrogenase 44 129 2.9E-12 T 06-07-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 LK06_RS00320 9f71fd8d675c8a2ffd90a613137e055d 464 Pfam PF00374 Nickel-dependent hydrogenase 340 455 7.9E-9 T 06-07-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 LK06_RS00320 9f71fd8d675c8a2ffd90a613137e055d 464 SUPERFAMILY SSF56762 6 455 2.88E-83 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS00320 9f71fd8d675c8a2ffd90a613137e055d 464 Gene3D G3DSA:1.10.645.10 6 455 2.7E-83 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS11520 c34cc88e7c193e73db917c073578ce16 302 Gene3D G3DSA:3.40.50.620 1 138 1.4E-32 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS11520 c34cc88e7c193e73db917c073578ce16 302 Gene3D G3DSA:3.40.50.620 160 299 3.5E-24 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LK06_RS11520 c34cc88e7c193e73db917c073578ce16 302 PRINTS PR01438 Universal stress protein signature 98 110 4.1E-12 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS11520 c34cc88e7c193e73db917c073578ce16 302 PRINTS PR01438 Universal stress protein signature 2 20 4.1E-12 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS11520 c34cc88e7c193e73db917c073578ce16 302 PRINTS PR01438 Universal stress protein signature 116 138 4.1E-12 T 06-07-2017 IPR006015 Universal stress protein A LK06_RS11520 c34cc88e7c193e73db917c073578ce16 302 SUPERFAMILY SSF52402 162 299 2.34E-21 T 06-07-2017 LK06_RS11520 c34cc88e7c193e73db917c073578ce16 302 Pfam PF00582 Universal stress protein family 162 299 8.2E-21 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS11520 c34cc88e7c193e73db917c073578ce16 302 Pfam PF00582 Universal stress protein family 1 138 5.0E-27 T 06-07-2017 IPR006016 UspA GO:0006950 LK06_RS11520 c34cc88e7c193e73db917c073578ce16 302 SUPERFAMILY SSF52402 3 140 4.27E-29 T 06-07-2017 LK06_RS28945 8381a4907094d49d021b05fbd4212fd1 252 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 4 237 6.9E-48 T 06-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 LK06_RS28945 8381a4907094d49d021b05fbd4212fd1 252 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 4 239 3.3E-69 T 06-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 LK06_RS30095 83958c7ef215a21d0a1af418220a645f 59 Pfam PF01526 Tn3 transposase DDE domain 2 54 6.0E-5 T 06-07-2017 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 LK06_RS30820 9d7599b1f91181b46e2ea00fe4267ac7 146 Pfam PF06236 Tyrosinase co-factor MelC1 13 143 2.0E-39 T 06-07-2017 IPR010928 Tyrosinase co-factor MelC1 GO:0005507|GO:0042438 LK06_RS31385 2772e055c170e64aa8d12158b6d3a228 314 SUPERFAMILY SSF53335 16 144 1.3E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS31385 2772e055c170e64aa8d12158b6d3a228 314 Gene3D G3DSA:3.40.50.150 22 142 1.4E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS31385 2772e055c170e64aa8d12158b6d3a228 314 Pfam PF13649 Methyltransferase domain 45 137 9.3E-15 T 06-07-2017 LK06_RS15565 ca6e09939d113c60b3befe03583f390a 176 Pfam PF00498 FHA domain 103 161 2.7E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS15565 ca6e09939d113c60b3befe03583f390a 176 Gene3D G3DSA:2.60.200.20 81 175 1.6E-26 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS15565 ca6e09939d113c60b3befe03583f390a 176 SUPERFAMILY SSF49879 56 175 4.21E-26 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 LK06_RS15565 ca6e09939d113c60b3befe03583f390a 176 SMART SM00240 102 153 1.1E-13 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LK06_RS25625 163d0db66427c984c83a6849cc05e99b 58 SUPERFAMILY SSF53098 7 46 1.06E-7 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS25625 163d0db66427c984c83a6849cc05e99b 58 Pfam PF01609 Transposase DDE domain 8 45 5.7E-7 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS25625 163d0db66427c984c83a6849cc05e99b 58 Gene3D G3DSA:3.90.350.10 7 47 3.3E-5 T 06-07-2017 IPR014736 Transposase, Tn5-like, core LK06_RS22095 60429e499bdc4fc510befed7c7bffb8a 201 Pfam PF01914 MarC family integral membrane protein 6 197 1.1E-46 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 LK06_RS22095 60429e499bdc4fc510befed7c7bffb8a 201 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 5 194 4.1E-44 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 LK06_RS03750 1636467252757efc0afc296e5e251a31 131 Pfam PF05331 Protein of unknown function (DUF742) 15 131 1.6E-37 T 06-07-2017 IPR007995 Protein of unknown function DUF742 LK06_RS25945 d89d8f35360fd20f7cd805a1db944715 460 Pfam PF09661 Protein of unknown function (DUF2398) 20 409 3.9E-110 T 06-07-2017 IPR013494 Conserved hypothetical protein CHP02678 LK06_RS25945 d89d8f35360fd20f7cd805a1db944715 460 TIGRFAM TIGR02678 TIGR02678: TIGR02678 family protein 19 413 9.5E-132 T 06-07-2017 IPR013494 Conserved hypothetical protein CHP02678 LK06_RS17145 c2d114a79ed5ef26c4fd95a4137c6255 436 Pfam PF12307 Protein of unknown function (DUF3631) 237 420 3.5E-69 T 06-07-2017 IPR022081 Domain of unknown function DUF3631 LK06_RS30295 d851bd7f1b9805a8b8afd5b038f81d6e 132 Pfam PF07179 SseB protein N-terminal domain 15 127 5.4E-14 T 06-07-2017 IPR009839 SseB protein N-terminal domain LK06_RS22395 309e968d140b7985f225f74358201246 418 SUPERFAMILY SSF109604 233 397 3.4E-10 T 06-07-2017 LK06_RS22395 309e968d140b7985f225f74358201246 418 Gene3D G3DSA:1.10.3210.10 254 370 6.2E-6 T 06-07-2017 IPR006674 HD domain LK06_RS06760 7d50e4efc2227b777107461b52e764b6 159 Pfam PF08592 Domain of unknown function (DUF1772) 22 157 4.8E-15 T 06-07-2017 IPR013901 Protein of unknown function DUF1772 LK06_RS08015 44d5c1adaa06d2fa810c9268289eb3ee 239 Pfam PF06224 Winged helix DNA-binding domain 14 219 1.4E-38 T 06-07-2017 IPR009351 Protein of unknown function DUF1006 LK06_RS29160 272deaa214d535ff765d53f5cb288bf8 105 Pfam PF13276 HTH-like domain 57 100 2.8E-11 T 06-07-2017 IPR025948 HTH-like domain LK06_RS14395 c4c9f8a970d426a6d9bd3df6d7cad512 134 SUPERFAMILY SSF103247 2 127 3.4E-37 T 06-07-2017 IPR005180 Domain of unknown function DUF302 LK06_RS14395 c4c9f8a970d426a6d9bd3df6d7cad512 134 PIRSF PIRSF021774 1 129 1.0E-43 T 06-07-2017 IPR016796 Uncharacterised conserved protein UCP021774 LK06_RS14395 c4c9f8a970d426a6d9bd3df6d7cad512 134 Gene3D G3DSA:3.30.310.70 3 126 1.1E-48 T 06-07-2017 IPR005180 Domain of unknown function DUF302 LK06_RS14395 c4c9f8a970d426a6d9bd3df6d7cad512 134 Pfam PF03625 Domain of unknown function DUF302 35 97 7.9E-26 T 06-07-2017 IPR005180 Domain of unknown function DUF302 LK06_RS16410 43b7ef9fe2f30b61528929a9c4404a3d 219 Pfam PF10935 Protein of unknown function (DUF2637) 6 119 5.1E-20 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 LK06_RS18550 0108d59945af5d6d10654171ed003145 88 Pfam PF10745 Protein of unknown function (DUF2530) 11 74 4.0E-7 T 06-07-2017 IPR019681 Protein of unknown function DUF2530 LK06_RS09635 658455166d0a69709a0f034e2a448c18 366 Gene3D G3DSA:3.30.2010.10 73 159 1.7E-20 T 06-07-2017 LK06_RS09635 658455166d0a69709a0f034e2a448c18 366 Pfam PF01435 Peptidase family M48 78 273 2.2E-24 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LK06_RS24590 6ec3bcdb723011927aff9a84ab12c248 420 Pfam PF13546 DDE superfamily endonuclease 20 290 1.2E-90 T 06-07-2017 LK06_RS24590 6ec3bcdb723011927aff9a84ab12c248 420 SUPERFAMILY SSF53098 10 411 1.29E-31 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 LK06_RS29285 86f84d1a8f3c8042364088b59c2b41cc 154 SUPERFAMILY SSF50475 7 133 1.59E-22 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS29285 86f84d1a8f3c8042364088b59c2b41cc 154 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 11 131 1.8E-26 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related LK06_RS29285 86f84d1a8f3c8042364088b59c2b41cc 154 Gene3D G3DSA:2.30.110.10 4 136 1.1E-40 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 LK06_RS09945 f899d9422d1017bc55b2e44b48da7634 168 SUPERFAMILY SSF109604 21 160 1.57E-24 T 06-07-2017 LK06_RS09945 f899d9422d1017bc55b2e44b48da7634 168 Pfam PF13328 HD domain 28 101 1.2E-8 T 06-07-2017 IPR003607 HD/PDEase domain LK06_RS26440 0a4ff5f0cb9c2f6d347f9a1d4a6e59b7 174 Gene3D G3DSA:3.40.50.2300 58 144 2.1E-6 T 06-07-2017 LK06_RS19060 91fc659e27d55f4b7abc941f095ccb1d 63 Pfam PF04149 Domain of unknown function (DUF397) 10 62 6.7E-22 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS21665 4dbbffd5b622f7a18afd4db5aee408ba 178 Pfam PF03691 Uncharacterised protein family (UPF0167) 5 177 1.0E-52 T 06-07-2017 IPR005363 Uncharacterised protein family UPF0167 LK06_RS02655 8005bf8c5261ac215262941d6cfc649e 218 Pfam PF05988 Bacterial protein of unknown function (DUF899) 2 216 8.0E-73 T 06-07-2017 IPR010296 Protein of unknown function DUF899, thioredoxin-like LK06_RS25955 6e36062fb3caad069b84b5c199f131a9 416 Pfam PF09664 Protein of unknown function C-terminus (DUF2399) 259 411 9.7E-47 T 06-07-2017 IPR024465 Domain of unknown function DUF2399 LK06_RS25955 6e36062fb3caad069b84b5c199f131a9 416 Pfam PF11796 Protein of unknown function N-terminus (DUF3323) 37 238 1.1E-49 T 06-07-2017 IPR024466 Conserved hypothetical protein CHP02679, N terminus LK06_RS25955 6e36062fb3caad069b84b5c199f131a9 416 TIGRFAM TIGR02679 TIGR02679: TIGR02679 family protein 32 411 1.9E-127 T 06-07-2017 IPR013495 Conserved hypothetical protein CHP02679 LK06_RS08605 5a5f610a0f5de85eaff31338a882ddb9 231 Pfam PF06912 Protein of unknown function (DUF1275) 25 224 1.1E-39 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 LK06_RS03225 f5bcdf8aebf9477046723fac68759fef 77 Gene3D G3DSA:3.90.350.10 20 65 1.9E-4 T 06-07-2017 IPR014736 Transposase, Tn5-like, core LK06_RS19670 21dd10cda98539ab293c58ae65afa45e 112 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 22 109 5.7E-23 T 06-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 LK06_RS16215 e2d01c07335a81bbd0f733ceaa359e8a 239 Pfam PF12679 ABC-2 family transporter protein 53 169 3.3E-9 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 LK06_RS02255 7434fa2c5db9eec21df6e152cd1a623e 316 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 38 279 3.0E-81 T 06-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related LK06_RS23180 6126badefc4d563d5336bdc749351d97 163 Pfam PF07508 Recombinase 53 161 5.1E-18 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 LK06_RS15775 f5737719050ec84e04b9fe6589f9900a 221 Pfam PF10935 Protein of unknown function (DUF2637) 9 124 1.9E-19 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 LK06_RS03690 bc3c07ee6a6ba76f6eba4c041b1496d0 149 SUPERFAMILY SSF51261 3 147 8.89E-37 T 06-07-2017 IPR011055 Duplicated hybrid motif LK06_RS03690 bc3c07ee6a6ba76f6eba4c041b1496d0 149 Gene3D G3DSA:2.70.70.10 3 148 7.0E-46 T 06-07-2017 LK06_RS03690 bc3c07ee6a6ba76f6eba4c041b1496d0 149 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 3 124 7.0E-39 T 06-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 LK06_RS14050 fa59b7a5c581662f091625ed6563ee2b 281 Pfam PF00482 Type II secretion system (T2SS), protein F 113 233 1.1E-7 T 06-07-2017 IPR018076 Type II secretion system F domain LK06_RS03805 2608818001f65cc678ed6e666d4a9e7f 472 SUPERFAMILY SSF48371 234 431 7.92E-6 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 LK06_RS18375 195230c65b281c7e6c8089b96eee1e38 139 Pfam PF01471 Putative peptidoglycan binding domain 73 129 3.4E-6 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18375 195230c65b281c7e6c8089b96eee1e38 139 Gene3D G3DSA:1.10.101.10 60 133 4.8E-14 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS18375 195230c65b281c7e6c8089b96eee1e38 139 SUPERFAMILY SSF47090 60 133 4.87E-12 T 06-07-2017 IPR002477 Peptidoglycan binding-like LK06_RS28905 2ca799a249a9eb48789adb7250d15356 391 Pfam PF04909 Amidohydrolase 92 373 2.4E-18 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 LK06_RS28905 2ca799a249a9eb48789adb7250d15356 391 Gene3D G3DSA:3.20.20.140 8 373 3.8E-108 T 06-07-2017 LK06_RS28905 2ca799a249a9eb48789adb7250d15356 391 SUPERFAMILY SSF51556 15 373 1.15E-12 T 06-07-2017 IPR032466 Metal-dependent hydrolase LK06_RS23380 304db7406d779edf8fb5c3dce5dd7760 223 Pfam PF01939 Protein of unknown function DUF91 2 223 7.6E-86 T 06-07-2017 IPR002793 Endonuclease NucS LK06_RS23380 304db7406d779edf8fb5c3dce5dd7760 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 215 31.507 T 06-07-2017 IPR002793 Endonuclease NucS LK06_RS20455 98b1854e18e792c1ff2a0bc5a8cd4965 275 SUPERFAMILY SSF103481 40 119 1.19E-5 T 06-07-2017 LK06_RS09525 375868e8fdb5fb61b26d8ed92d127d9d 624 SUPERFAMILY SSF56801 358 619 3.4E-117 T 06-07-2017 LK06_RS09525 375868e8fdb5fb61b26d8ed92d127d9d 624 SUPERFAMILY SSF56801 8 301 3.4E-117 T 06-07-2017 LK06_RS09525 375868e8fdb5fb61b26d8ed92d127d9d 624 Gene3D G3DSA:3.40.50.980 206 296 1.8E-25 T 06-07-2017 LK06_RS09525 375868e8fdb5fb61b26d8ed92d127d9d 624 Gene3D G3DSA:3.40.50.980 355 417 1.8E-25 T 06-07-2017 LK06_RS09525 375868e8fdb5fb61b26d8ed92d127d9d 624 Gene3D G3DSA:3.40.50.980 14 205 3.4E-35 T 06-07-2017 LK06_RS09525 375868e8fdb5fb61b26d8ed92d127d9d 624 Gene3D G3DSA:2.30.38.10 418 479 1.2E-21 T 06-07-2017 LK06_RS09525 375868e8fdb5fb61b26d8ed92d127d9d 624 Pfam PF00501 AMP-binding enzyme 21 488 3.1E-97 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 LK06_RS09525 375868e8fdb5fb61b26d8ed92d127d9d 624 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 06-07-2017 IPR020845 AMP-binding, conserved site LK06_RS27390 6bdce71bf24978314394de2be0216b24 120 Pfam PF13309 HTH domain 54 115 1.0E-20 T 06-07-2017 LK06_RS27390 6bdce71bf24978314394de2be0216b24 120 Gene3D G3DSA:1.10.10.60 86 116 6.1E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS29815 ae7d4a4ae6739e3f17e7b38a849f054c 345 SUPERFAMILY SSF51004 37 327 1.02E-38 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain LK06_RS29815 ae7d4a4ae6739e3f17e7b38a849f054c 345 Gene3D G3DSA:2.130.10.10 11 344 1.3E-89 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 LK06_RS29815 ae7d4a4ae6739e3f17e7b38a849f054c 345 Pfam PF10282 Lactonase, 7-bladed beta-propeller 12 344 1.1E-87 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 LK06_RS18870 21dbdf19f654397874a86d3d3bfdfd7e 149 Pfam PF07681 DoxX 54 109 7.6E-6 T 06-07-2017 IPR032808 DoxX family LK06_RS22460 71b764835aefc46689f1c36b1596cbcb 85 Pfam PF02467 Transcription factor WhiB 3 71 1.8E-27 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS22460 71b764835aefc46689f1c36b1596cbcb 85 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 19.028 T 06-07-2017 IPR003482 Transcription factor WhiB LK06_RS07645 d161dc42178ee19fe6d58ca862ade352 132 PIRSF PIRSF017385 1 131 2.9E-50 T 06-07-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 LK06_RS07645 d161dc42178ee19fe6d58ca862ade352 132 Pfam PF12270 Cytochrome c oxidase subunit IV 2 129 4.5E-53 T 06-07-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 LK06_RS19795 a5c46957cd36dc4b33d77840fe9a6e8c 126 Gene3D G3DSA:3.10.180.10 6 117 8.2E-40 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS19795 a5c46957cd36dc4b33d77840fe9a6e8c 126 SUPERFAMILY SSF54593 4 120 8.66E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS17850 d77e485865dbadd39898cbe982ce543d 222 SUPERFAMILY SSF110087 42 159 1.31E-6 T 06-07-2017 IPR007410 DR1885-like metal-binding protein LK06_RS25735 221efbb72f8dc647a92052c4fd835168 65 Pfam PF04149 Domain of unknown function (DUF397) 12 61 7.5E-20 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS30570 5c443c4840f252159b8dffbee4dde95f 194 Pfam PF01810 LysE type translocator 8 192 3.2E-15 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 LK06_RS25360 b595a8f26b6b21abad7f470e0e9fe852 361 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 11 179 8.5E-40 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain LK06_RS25360 b595a8f26b6b21abad7f470e0e9fe852 361 Gene3D G3DSA:3.40.50.300 9 200 4.4E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS25360 b595a8f26b6b21abad7f470e0e9fe852 361 Gene3D G3DSA:3.30.1220.10 216 326 2.7E-17 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LK06_RS25360 b595a8f26b6b21abad7f470e0e9fe852 361 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 238 327 1.4E-18 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LK06_RS25360 b595a8f26b6b21abad7f470e0e9fe852 361 SMART SM00833 237 328 1.4E-8 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LK06_RS25360 b595a8f26b6b21abad7f470e0e9fe852 361 SUPERFAMILY SSF90002 238 326 6.8E-15 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LK06_RS25360 b595a8f26b6b21abad7f470e0e9fe852 361 SUPERFAMILY SSF52540 9 199 1.0E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS18135 a5c3373fbc7ca52ada27bbe285a5c446 366 Pfam PF01758 Sodium Bile acid symporter family 68 260 3.4E-32 T 06-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 LK06_RS24850 40a2616983743179dcc41940b0a899a3 100 Pfam PF06013 Proteins of 100 residues with WXG 9 92 5.7E-16 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like LK06_RS24850 40a2616983743179dcc41940b0a899a3 100 SUPERFAMILY SSF140453 8 99 1.27E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like LK06_RS24850 40a2616983743179dcc41940b0a899a3 100 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 9 97 2.3E-18 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like LK06_RS24850 40a2616983743179dcc41940b0a899a3 100 Gene3D G3DSA:1.10.287.1060 8 99 8.2E-20 T 06-07-2017 LK06_RS27740 a686c9d1d3281bfc52ea28e098d06c13 325 Pfam PF00296 Luciferase-like monooxygenase 35 292 1.3E-21 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS27740 a686c9d1d3281bfc52ea28e098d06c13 325 Gene3D G3DSA:3.20.20.30 18 308 4.9E-31 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS27740 a686c9d1d3281bfc52ea28e098d06c13 325 SUPERFAMILY SSF51679 15 309 2.86E-29 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LK06_RS14215 e542f832fa9488759ffa6870be623c41 396 Pfam PF01609 Transposase DDE domain 139 364 6.9E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS14215 e542f832fa9488759ffa6870be623c41 396 Pfam PF13808 DDE_Tnp_1-associated 32 125 5.8E-23 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS15145 766fef403dc2989c803352460fbd9333 432 PRINTS PR00758 Arsenical pump membrane protein signature 279 303 4.0E-16 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 LK06_RS15145 766fef403dc2989c803352460fbd9333 432 PRINTS PR00758 Arsenical pump membrane protein signature 367 392 4.0E-16 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 LK06_RS15145 766fef403dc2989c803352460fbd9333 432 PRINTS PR00758 Arsenical pump membrane protein signature 222 247 4.0E-16 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 LK06_RS15145 766fef403dc2989c803352460fbd9333 432 PRINTS PR00758 Arsenical pump membrane protein signature 106 130 4.0E-16 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 LK06_RS15145 766fef403dc2989c803352460fbd9333 432 PRINTS PR00758 Arsenical pump membrane protein signature 400 424 4.0E-16 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 LK06_RS15145 766fef403dc2989c803352460fbd9333 432 Pfam PF03600 Citrate transporter 17 371 2.3E-49 T 06-07-2017 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 LK06_RS08345 76ce58ec45306516b247fa36ca7f45d2 181 Pfam PF07681 DoxX 10 95 2.0E-13 T 06-07-2017 IPR032808 DoxX family LK06_RS13540 815db5028e584ce5f307d35b352210e2 265 SUPERFAMILY SSF53335 1 159 8.6E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS13540 815db5028e584ce5f307d35b352210e2 265 Gene3D G3DSA:3.40.50.150 18 159 1.2E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS13540 815db5028e584ce5f307d35b352210e2 265 Pfam PF08241 Methyltransferase domain 58 147 9.5E-15 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 LK06_RS14830 59fab9c67b2f446f7c2cf85f7dd4bca7 72 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 37 1.1E-4 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 LK06_RS31340 abeae36c4fbc1428e3dabc4fd4cd0448 607 Pfam PF04185 Phosphoesterase family 252 459 6.6E-15 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 LK06_RS29065 6c74eb8418993f3dde85c52de7605fc3 209 Pfam PF05908 Poly-gamma-glutamate hydrolase 28 175 9.1E-17 T 06-07-2017 IPR008585 Poly-gamma-glutamate hydrolase LK06_RS19505 fd14e79c2a6e6c332d9d946c804c3865 108 Gene3D G3DSA:3.40.50.1390 9 94 3.4E-5 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 LK06_RS00570 e83dc09fa662231c4eaf26d8bb36923c 402 Pfam PF09375 Imelysin 163 358 1.2E-16 T 06-07-2017 LK06_RS10625 3ca037862b0dbb9b24d52cdd91d68ffd 65 Pfam PF04149 Domain of unknown function (DUF397) 6 59 8.0E-21 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS13390 40883ca816e8a56e4c974b36276bb8b9 118 Pfam PF05656 Protein of unknown function (DUF805) 11 111 3.6E-31 T 06-07-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 LK06_RS07755 549fa261416a80c3319a8d8928c7b40d 591 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 254 552 8.0E-110 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal LK06_RS07755 549fa261416a80c3319a8d8928c7b40d 591 SUPERFAMILY SSF103473 213 240 3.66E-5 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS07755 549fa261416a80c3319a8d8928c7b40d 591 SUPERFAMILY SSF103473 22 174 3.66E-5 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS07755 549fa261416a80c3319a8d8928c7b40d 591 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 24 231 4.8E-14 T 06-07-2017 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 LK06_RS21890 c1c300f6320c6f62df6a606477f9d854 307 SUPERFAMILY SSF161098 90 288 1.02E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21890 c1c300f6320c6f62df6a606477f9d854 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 6.6E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS21890 c1c300f6320c6f62df6a606477f9d854 307 Gene3D G3DSA:1.10.3720.10 89 302 1.7E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS13330 04f78506dfe72d7c9d6ca90645379647 397 SUPERFAMILY SSF103365 10 397 3.53E-130 T 06-07-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 LK06_RS13330 04f78506dfe72d7c9d6ca90645379647 397 Pfam PF01139 tRNA-splicing ligase RtcB 29 397 1.3E-130 T 06-07-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 LK06_RS21395 43873f804a7a29ce8078799fad8e7f95 780 Pfam PF02687 FtsX-like permease family 663 770 7.2E-8 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS29030 7c4c694b6c5478d974c9e8fc04fa52c8 358 Pfam PF02653 Branched-chain amino acid transport system / permease component 67 344 4.0E-55 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 LK06_RS31360 a9456d05a89a203ea59edfb67d8a5a38 499 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 346 430 3.6E-15 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain LK06_RS31360 a9456d05a89a203ea59edfb67d8a5a38 499 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 77 232 6.2E-39 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS31360 a9456d05a89a203ea59edfb67d8a5a38 499 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 77 232 2.8E-42 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain LK06_RS12690 ba83444202f15f0e221e56e3b2d8d9d8 459 Pfam PF13796 Putative sensor 53 241 2.0E-46 T 06-07-2017 IPR025828 Putative sensor domain LK06_RS12690 ba83444202f15f0e221e56e3b2d8d9d8 459 Gene3D G3DSA:3.30.565.10 375 455 2.5E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS12690 ba83444202f15f0e221e56e3b2d8d9d8 459 SUPERFAMILY SSF55874 348 455 3.56E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS12690 ba83444202f15f0e221e56e3b2d8d9d8 459 Pfam PF07730 Histidine kinase 269 334 9.9E-13 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS31870 ae28627f10305ec81c964d0999f62c75 131 SUPERFAMILY SSF51126 3 121 8.17E-7 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor LK06_RS24030 0e9dc1807cd777755ced3784c5f87a73 480 PIRSF PIRSF002744 1 470 6.2E-71 T 06-07-2017 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 LK06_RS24030 0e9dc1807cd777755ced3784c5f87a73 480 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 10 448 4.9E-104 T 06-07-2017 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 LK06_RS05185 ebccdb93f5b6366c06bc10fac660c10a 266 Pfam PF03777 Small secreted domain (DUF320) 90 142 8.8E-21 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS05185 ebccdb93f5b6366c06bc10fac660c10a 266 Pfam PF03777 Small secreted domain (DUF320) 24 78 1.1E-26 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS18510 ca2ba816bbb973b227b7fbbeb1b269a5 23 Pfam PF04149 Domain of unknown function (DUF397) 3 21 3.3E-7 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS04330 88b65303dd62cd6df9f3f2d140662042 247 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 87 109 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS04330 88b65303dd62cd6df9f3f2d140662042 247 Pfam PF01066 CDP-alcohol phosphatidyltransferase 45 109 2.2E-10 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LK06_RS02470 4b9b843c58cea77915715894f802a943 324 Pfam PF08012 Protein of unknown function (DUF1702) 5 317 3.2E-131 T 06-07-2017 IPR012964 Protein of unknown function DUF1702 LK06_RS21190 2529a705fee3fec28b1104aafde623fd 203 Pfam PF08044 Domain of unknown function (DUF1707) 25 76 2.5E-16 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 LK06_RS22080 80feb7441ac7ba6b66b345e5916cba19 194 Pfam PF05076 Suppressor of fused protein (SUFU) 29 189 8.9E-36 T 06-07-2017 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 LK06_RS00545 b7e2cbc90535cad4924565db1df92844 306 SUPERFAMILY SSF103481 49 121 6.02E-7 T 06-07-2017 LK06_RS02520 9db983128bd51f8c4d306d717c6d13e4 112 SUPERFAMILY SSF52091 18 92 2.16E-5 T 06-07-2017 IPR002645 STAS domain LK06_RS02520 9db983128bd51f8c4d306d717c6d13e4 112 Gene3D G3DSA:3.30.750.24 21 93 3.7E-4 T 06-07-2017 IPR002645 STAS domain LK06_RS08640 a2e31078adfb262cbad304c9f5602049 192 Pfam PF00583 Acetyltransferase (GNAT) family 70 146 2.9E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS08640 a2e31078adfb262cbad304c9f5602049 192 Gene3D G3DSA:3.40.630.30 12 165 4.1E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS08640 a2e31078adfb262cbad304c9f5602049 192 SUPERFAMILY SSF55729 11 162 1.15E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS10350 197928cd8f9cd7e5c09533751348487f 457 Pfam PF04932 O-Antigen ligase 205 361 5.4E-13 T 06-07-2017 IPR007016 O-antigen ligase-related LK06_RS04670 4c07075017d7a465327a36ddcee88e0b 167 Pfam PF04205 FMN-binding domain 89 162 1.1E-9 T 06-07-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 LK06_RS04670 4c07075017d7a465327a36ddcee88e0b 167 SMART SM00900 87 165 4.2E-14 T 06-07-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 LK06_RS15820 6fc2ecd6302e783666ea6ab47a5ac22c 242 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 122 240 5.5E-40 T 06-07-2017 IPR021949 Domain of unknown function DUF3566. transmembrane LK06_RS09025 1ebfd681cbe1a39a000f10a276584757 374 SUPERFAMILY SSF51395 9 359 2.54E-94 T 06-07-2017 LK06_RS09025 1ebfd681cbe1a39a000f10a276584757 374 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 16 359 4.5E-61 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 LK06_RS09025 1ebfd681cbe1a39a000f10a276584757 374 Gene3D G3DSA:3.20.20.70 8 360 2.7E-99 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS01925 e0fb126fd5be21aad154be0e407c4a80 193 Pfam PF14325 Domain of unknown function (DUF4383) 18 132 1.4E-14 T 06-07-2017 IPR025492 Protein of unknown function DUF4383 LK06_RS17155 648fe65af61b4c8442b48c1e3c1b1252 189 Pfam PF05713 Bacterial mobilisation protein (MobC) 133 164 1.9E-9 T 06-07-2017 IPR008687 Bacterial mobilisation LK06_RS13880 39dc8ffc2c17f299f38437d44f0ff0ee 72 Pfam PF04149 Domain of unknown function (DUF397) 10 62 2.1E-17 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS15620 5681ed7df47a241f4527c81f7a9a6fb9 261 Pfam PF05949 Bacterial protein of unknown function (DUF881) 104 258 6.8E-41 T 06-07-2017 IPR010273 Protein of unknown function DUF881 LK06_RS17415 4342d8bf520625aef9699701e912650b 115 Pfam PF04149 Domain of unknown function (DUF397) 5 56 1.5E-10 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS28440 0d268f70100ca9798da39f99fc8305e3 301 Pfam PF00149 Calcineurin-like phosphoesterase 10 243 1.3E-15 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 LK06_RS28440 0d268f70100ca9798da39f99fc8305e3 301 Gene3D G3DSA:3.60.21.10 10 84 6.5E-23 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS28440 0d268f70100ca9798da39f99fc8305e3 301 Gene3D G3DSA:3.60.21.10 178 262 6.5E-23 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS28440 0d268f70100ca9798da39f99fc8305e3 301 SUPERFAMILY SSF56300 175 262 1.35E-26 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS28440 0d268f70100ca9798da39f99fc8305e3 301 SUPERFAMILY SSF56300 6 135 1.35E-26 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like LK06_RS22260 7f2ba123dfde3da803afa76ccb1e5861 198 Pfam PF01863 Protein of unknown function DUF45 96 180 1.5E-22 T 06-07-2017 IPR002725 Protein of unknown function DUF45 LK06_RS21945 2de0dc6012b3f3dca54771f83202154f 392 SUPERFAMILY SSF55874 289 386 6.48E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS21945 2de0dc6012b3f3dca54771f83202154f 392 Pfam PF07730 Histidine kinase 197 262 2.5E-18 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LK06_RS21745 903a66dbe07f0c80ba1d4928e07ee0cd 363 Pfam PF13828 Domain of unknown function (DUF4190) 23 79 1.6E-16 T 06-07-2017 IPR025241 Domain of unknown function DUF4190 LK06_RS21745 903a66dbe07f0c80ba1d4928e07ee0cd 363 Pfam PF13845 Septum formation 96 201 4.3E-10 T 06-07-2017 IPR026004 Septum formation-related domain LK06_RS27150 aa0758f139eba98b7845fdfe3f9a3244 383 Pfam PF02625 XdhC and CoxI family 11 78 1.3E-22 T 06-07-2017 IPR003777 XdhC- CoxI LK06_RS27150 aa0758f139eba98b7845fdfe3f9a3244 383 Pfam PF02625 XdhC and CoxI family 118 183 1.3E-11 T 06-07-2017 IPR003777 XdhC- CoxI LK06_RS27150 aa0758f139eba98b7845fdfe3f9a3244 383 Pfam PF13478 XdhC Rossmann domain 206 348 5.9E-41 T 06-07-2017 IPR027051 XdhC Rossmann domain LK06_RS19950 0756e3a5f7375189306cf80a6bfbebd6 158 Pfam PF04977 Septum formation initiator 47 124 2.3E-17 T 06-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 LK06_RS13750 7df7d32e7af4f63b1200cfabc29b17e8 452 PIRSF PIRSF026631 24 445 5.4E-152 T 06-07-2017 IPR014529 Uncharacterised conserved protein UCP026631 LK06_RS13750 7df7d32e7af4f63b1200cfabc29b17e8 452 Pfam PF03703 Bacterial PH domain 88 165 1.6E-16 T 06-07-2017 IPR005182 Domain of unknown function DUF304 LK06_RS13750 7df7d32e7af4f63b1200cfabc29b17e8 452 Pfam PF03703 Bacterial PH domain 262 328 2.1E-8 T 06-07-2017 IPR005182 Domain of unknown function DUF304 LK06_RS13750 7df7d32e7af4f63b1200cfabc29b17e8 452 Pfam PF03703 Bacterial PH domain 356 430 4.1E-11 T 06-07-2017 IPR005182 Domain of unknown function DUF304 LK06_RS03520 65812d53fab2d423158788a56f07caa6 123 Pfam PF13586 Transposase DDE domain 22 101 3.6E-15 T 06-07-2017 IPR025668 Transposase DDE domain LK06_RS16295 0846dcc157c658681d21f189a06d19ff 460 Gene3D G3DSA:3.30.450.40 55 176 1.5E-6 T 06-07-2017 IPR029016 GAF domain-like LK06_RS16295 0846dcc157c658681d21f189a06d19ff 460 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 267 460 3.5E-36 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS16295 0846dcc157c658681d21f189a06d19ff 460 SMART SM00331 240 459 2.8E-15 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 LK06_RS16295 0846dcc157c658681d21f189a06d19ff 460 SUPERFAMILY SSF55781 74 222 2.29E-5 T 06-07-2017 IPR029016 GAF domain-like LK06_RS06815 80e925284f3ee867d6494bea984b193e 588 Pfam PF13515 Fusaric acid resistance protein-like 339 457 1.7E-15 T 06-07-2017 LK06_RS17435 d2e8477248e1d425b4ff18b554312b46 317 SUPERFAMILY SSF103481 43 150 1.44E-6 T 06-07-2017 LK06_RS17435 d2e8477248e1d425b4ff18b554312b46 317 Pfam PF00892 EamA-like transporter family 9 147 3.1E-20 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS17435 d2e8477248e1d425b4ff18b554312b46 317 Pfam PF00892 EamA-like transporter family 166 301 1.7E-6 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 LK06_RS16555 3ded86df253f99070b18df0d045e4b3c 83 Pfam PF13586 Transposase DDE domain 14 64 1.8E-12 T 06-07-2017 IPR025668 Transposase DDE domain LK06_RS13735 c4dfae72ce4aa5dee27a691b641ad6e0 331 SUPERFAMILY SSF53335 2 220 3.99E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS13735 c4dfae72ce4aa5dee27a691b641ad6e0 331 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 70 220 1.4E-11 T 06-07-2017 IPR003788 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA Reactome: R-HSA-6799198 LK06_RS00010 8a8434b591095974bc5ccce870913969 217 SUPERFAMILY SSF55961 46 199 1.12E-12 T 06-07-2017 LK06_RS00010 8a8434b591095974bc5ccce870913969 217 Gene3D G3DSA:3.30.530.20 46 160 9.6E-4 T 06-07-2017 IPR023393 START-like domain LK06_RS28315 b649c33fc39c4988d5bcef3cb22872a9 301 SUPERFAMILY SSF53335 52 165 3.21E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28315 b649c33fc39c4988d5bcef3cb22872a9 301 Gene3D G3DSA:3.40.50.150 54 160 2.1E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS28315 b649c33fc39c4988d5bcef3cb22872a9 301 Pfam PF13649 Methyltransferase domain 69 161 2.6E-6 T 06-07-2017 LK06_RS01185 8575eb399dade3f69d5d5d5761f83fbc 102 Pfam PF14019 Protein of unknown function (DUF4235) 15 91 1.1E-24 T 06-07-2017 IPR025329 Protein of unknown function DUF4235 LK06_RS18440 18fab36a4e49c10e75c9c5bbecc10bee 892 Pfam PF13625 Helicase conserved C-terminal domain 601 723 4.1E-43 T 06-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 LK06_RS28135 22dcb630aa2a98455c3210fe804d6a88 212 Pfam PF09335 SNARE associated Golgi protein 47 173 9.4E-12 T 06-07-2017 IPR032816 SNARE associated Golgi protein LK06_RS03850 eaa8d9b8b44ad861212c017394284666 185 Pfam PF04186 FxsA cytoplasmic membrane protein 26 131 3.9E-29 T 06-07-2017 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 LK06_RS15530 10781a4ad429a508ee9c39c253f86c1f 455 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 52 443 2.1E-135 T 06-07-2017 IPR018721 Protein of unknown function DUF2252 LK06_RS06060 5952ec481ef6f53327bbe2c18ea24c29 117 Pfam PF04341 Protein of unknown function, DUF485 25 110 3.7E-30 T 06-07-2017 IPR007436 Protein of unknown function DUF485 LK06_RS21000 3b2a8509ba79bd07d1318b75d75af7ad 132 Pfam PF14155 Domain of unknown function (DUF4307) 22 129 4.5E-30 T 06-07-2017 IPR025443 Protein of unknown function DUF4307 LK06_RS25910 d7e58a50c31535b02f174d250aacd2b1 506 Pfam PF02706 Chain length determinant protein 16 140 1.6E-10 T 06-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 LK06_RS27220 eec91984116aa1b6789ef75d73c5eebf 336 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 299 3.7E-70 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS27220 eec91984116aa1b6789ef75d73c5eebf 336 Gene3D G3DSA:3.40.50.1100 44 141 2.7E-33 T 06-07-2017 LK06_RS27220 eec91984116aa1b6789ef75d73c5eebf 336 Gene3D G3DSA:3.40.50.1100 142 307 7.3E-69 T 06-07-2017 LK06_RS27220 eec91984116aa1b6789ef75d73c5eebf 336 TIGRFAM TIGR01136 cysKM: cysteine synthase 14 307 2.4E-104 T 06-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 LK06_RS27220 eec91984116aa1b6789ef75d73c5eebf 336 SUPERFAMILY SSF53686 10 309 4.45E-94 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme LK06_RS14430 b1a40e42758d2b8c9290159df6b886a2 149 Gene3D G3DSA:3.30.300.20 16 148 3.3E-32 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta LK06_RS14430 b1a40e42758d2b8c9290159df6b886a2 149 SUPERFAMILY SSF82784 7 148 2.22E-29 T 06-07-2017 IPR003718 OsmC/Ohr family LK06_RS14430 b1a40e42758d2b8c9290159df6b886a2 149 Pfam PF02566 OsmC-like protein 51 147 1.8E-15 T 06-07-2017 IPR003718 OsmC/Ohr family LK06_RS07370 e4e5f697045a4960c8778bab75d8eef0 256 Gene3D G3DSA:3.40.50.150 24 206 7.0E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07370 e4e5f697045a4960c8778bab75d8eef0 256 SUPERFAMILY SSF53335 13 204 1.81E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS07370 e4e5f697045a4960c8778bab75d8eef0 256 Pfam PF13649 Methyltransferase domain 38 134 1.7E-13 T 06-07-2017 LK06_RS31160 acf4d0c2f4b0c83f6e875af78a6905ab 337 Pfam PF05231 MASE1 18 290 4.3E-49 T 06-07-2017 IPR007895 MASE1 LK06_RS30470 4f631c3c37388a20460a376df18ece36 251 Pfam PF07335 Fungal chitosanase of glycosyl hydrolase group 75 87 219 5.4E-25 T 06-07-2017 IPR009939 Fungal chitosanase KEGG: 00520+3.2.1.132 LK06_RS04405 4239a0027bd18e9f92495d83ed3a83ca 272 SUPERFAMILY SSF53474 1 242 1.98E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS04405 4239a0027bd18e9f92495d83ed3a83ca 272 Gene3D G3DSA:3.40.50.1820 4 268 1.6E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold LK06_RS04405 4239a0027bd18e9f92495d83ed3a83ca 272 Pfam PF12146 Serine aminopeptidase, S33 27 143 4.0E-22 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 LK06_RS04405 4239a0027bd18e9f92495d83ed3a83ca 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 4.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS04405 4239a0027bd18e9f92495d83ed3a83ca 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 4.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS04405 4239a0027bd18e9f92495d83ed3a83ca 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 4.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 LK06_RS27580 20055dd862b5241b5e205eaa6194ba6b 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 331 4.7E-50 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 LK06_RS18915 97b90e6b5773c1e062c621576118f12e 207 Pfam PF01810 LysE type translocator 16 202 6.2E-24 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 LK06_RS14100 6a024d44406d16ede08abacef84a12f7 162 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 16 134 2.6E-22 T 06-07-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III LK06_RS01440 ad10d931122b40cce726fefee0ef18f5 259 Pfam PF03988 Repeat of Unknown Function (DUF347) 146 190 4.8E-8 T 06-07-2017 IPR007136 Protein of unknown function DUF347 LK06_RS01440 ad10d931122b40cce726fefee0ef18f5 259 Pfam PF03988 Repeat of Unknown Function (DUF347) 200 255 5.6E-11 T 06-07-2017 IPR007136 Protein of unknown function DUF347 LK06_RS01440 ad10d931122b40cce726fefee0ef18f5 259 Pfam PF03988 Repeat of Unknown Function (DUF347) 81 132 2.1E-14 T 06-07-2017 IPR007136 Protein of unknown function DUF347 LK06_RS01440 ad10d931122b40cce726fefee0ef18f5 259 Pfam PF03988 Repeat of Unknown Function (DUF347) 28 77 3.0E-11 T 06-07-2017 IPR007136 Protein of unknown function DUF347 LK06_RS25520 9a0adcb8ddc1751a988c01486ae1e76b 682 Pfam PF13520 Amino acid permease 59 477 6.5E-33 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS14365 224ad7934719d8b2b873f73510671dcd 320 SUPERFAMILY SSF143631 12 294 2.88E-62 T 06-07-2017 IPR003374 ApbE-like domain LK06_RS14365 224ad7934719d8b2b873f73510671dcd 320 Pfam PF02424 ApbE family 35 288 5.6E-55 T 06-07-2017 IPR024932 Flavin transferase ApbE GO:0017013 LK06_RS06445 31f502093d7414ff8e9e3954c5440464 270 SUPERFAMILY SSF110221 134 269 5.1E-31 T 06-07-2017 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 LK06_RS06445 31f502093d7414ff8e9e3954c5440464 270 Gene3D G3DSA:2.80.10.50 127 267 6.9E-35 T 06-07-2017 LK06_RS06445 31f502093d7414ff8e9e3954c5440464 270 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 136 264 8.1E-37 T 06-07-2017 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 LK06_RS10490 913ab4e36ee7e9d8eccdadeee8393205 238 SUPERFAMILY SSF53335 20 219 8.44E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS10490 913ab4e36ee7e9d8eccdadeee8393205 238 Pfam PF13649 Methyltransferase domain 42 130 9.3E-12 T 06-07-2017 LK06_RS10490 913ab4e36ee7e9d8eccdadeee8393205 238 Gene3D G3DSA:3.40.50.150 191 217 1.5E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS10490 913ab4e36ee7e9d8eccdadeee8393205 238 Gene3D G3DSA:3.40.50.150 18 158 1.5E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LK06_RS26985 a0a1456dc36ee220855b4c5d0f3e4a67 433 Pfam PF01590 GAF domain 109 216 1.5E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 LK06_RS07465 40729f7cb8b441c498948483bacd5e85 88 Pfam PF04324 BFD-like [2Fe-2S] binding domain 15 63 1.2E-11 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain LK06_RS05875 3afd505135e1da43febec491d5df9c1f 260 Pfam PF07070 SpoOM protein 3 216 4.4E-79 T 06-07-2017 IPR009776 Sporulation stage 0, protein M LK06_RS22700 d3640a3fa4681d13aed346520ca8f376 262 Pfam PF13672 Protein phosphatase 2C 14 229 2.6E-8 T 06-07-2017 LK06_RS24670 79ee1692f29164dba5ac413b1515b8be 708 Gene3D G3DSA:3.40.50.300 295 378 2.0E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24670 79ee1692f29164dba5ac413b1515b8be 708 Gene3D G3DSA:3.40.50.300 500 650 2.0E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS24670 79ee1692f29164dba5ac413b1515b8be 708 SUPERFAMILY SSF52540 289 628 9.53E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS30265 e182320a25693b1f5762d90511b3b847 216 Pfam PF03729 Short repeat of unknown function (DUF308) 100 157 2.7E-8 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane LK06_RS30265 e182320a25693b1f5762d90511b3b847 216 Pfam PF03729 Short repeat of unknown function (DUF308) 157 207 2.1E-5 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane LK06_RS30265 e182320a25693b1f5762d90511b3b847 216 Pfam PF03729 Short repeat of unknown function (DUF308) 46 113 1.5E-15 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane LK06_RS24770 275d45ea597b675361fda160d3028b7c 97 SUPERFAMILY SSF103007 1 94 1.31E-31 T 06-07-2017 IPR007546 Protein of unknown function DUF503 LK06_RS24770 275d45ea597b675361fda160d3028b7c 97 Pfam PF04456 Protein of unknown function (DUF503) 3 89 1.1E-32 T 06-07-2017 IPR007546 Protein of unknown function DUF503 LK06_RS24770 275d45ea597b675361fda160d3028b7c 97 Gene3D G3DSA:3.30.70.1120 1 96 4.9E-37 T 06-07-2017 IPR007546 Protein of unknown function DUF503 LK06_RS02150 a7183d963b6b0c15edd07550fd476097 214 Pfam PF09335 SNARE associated Golgi protein 38 168 2.2E-18 T 06-07-2017 IPR032816 SNARE associated Golgi protein LK06_RS30550 b15410aabb00176650c2426beda8e8b0 370 Pfam PF03060 Nitronate monooxygenase 12 350 5.9E-46 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 LK06_RS30550 b15410aabb00176650c2426beda8e8b0 370 Gene3D G3DSA:3.20.20.70 106 345 4.6E-53 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS30550 b15410aabb00176650c2426beda8e8b0 370 Gene3D G3DSA:3.20.20.70 1 71 4.6E-53 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 LK06_RS30550 b15410aabb00176650c2426beda8e8b0 370 SUPERFAMILY SSF51412 93 309 4.12E-43 T 06-07-2017 LK06_RS30550 b15410aabb00176650c2426beda8e8b0 370 SUPERFAMILY SSF51412 22 58 4.12E-43 T 06-07-2017 LK06_RS09035 72908f2ccd77c1b0850d0f4ee7594f6b 85 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 48 1.4E-8 T 06-07-2017 IPR019239 Bacterial antitoxin of type II TA system, VapB LK06_RS15030 59d82c406700c10254a84e8496245a51 318 Pfam PF00146 NADH dehydrogenase 14 306 6.3E-38 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS04325 11474e65d334e85a29190ebf1580f0d7 302 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 8 292 1.6E-62 T 06-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 LK06_RS02725 aff78aceb698285dddce51a64c7d580b 191 Gene3D G3DSA:3.90.470.20 113 162 6.1E-4 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS15000 0c5bdda4b6ef2b982230d955800d4fea 122 Gene3D G3DSA:3.30.565.10 8 121 3.5E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS15000 0c5bdda4b6ef2b982230d955800d4fea 122 SUPERFAMILY SSF55874 26 115 5.31E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain LK06_RS11120 f5566d7e7d8b9b573920df3fc7e6e74b 109 Pfam PF12277 Protein of unknown function (DUF3618) 7 52 2.1E-16 T 06-07-2017 IPR022062 Protein of unknown function DUF3618 LK06_RS01240 5bda5d41c13e5ccff694c62ec7157b59 164 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 161 4.3E-62 T 06-07-2017 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger LK06_RS06230 39cb0edb3e87adc70a235eae4964f908 314 Pfam PF03186 CobD/Cbib protein 12 290 1.5E-85 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 LK06_RS06230 39cb0edb3e87adc70a235eae4964f908 314 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 15 292 1.5E-50 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 LK06_RS06230 39cb0edb3e87adc70a235eae4964f908 314 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 312 93.958 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 LK06_RS04620 c46ca90bf2e7798bfd0bf7e7b5aab6b6 395 SUPERFAMILY SSF51695 61 386 6.28E-73 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS04620 c46ca90bf2e7798bfd0bf7e7b5aab6b6 395 Gene3D G3DSA:3.20.20.190 62 386 1.9E-85 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 LK06_RS04620 c46ca90bf2e7798bfd0bf7e7b5aab6b6 395 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 67 384 3.9E-45 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 LK06_RS07085 8aecd4a2be3d61b4793c6526ecf78d92 144 Pfam PF10825 Protein of unknown function (DUF2752) 50 98 1.1E-18 T 06-07-2017 IPR021215 Protein of unknown function DUF2752 LK06_RS13530 98d329c25c3a5d2c7dff5a8420a40493 262 Pfam PF01061 ABC-2 type transporter 27 225 1.0E-34 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS13530 98d329c25c3a5d2c7dff5a8420a40493 262 PIRSF PIRSF006648 1 262 3.9E-20 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 LK06_RS10580 a211d5825f4b20b95c6f686e013ae366 74 Pfam PF12728 Helix-turn-helix domain 19 66 8.9E-10 T 06-07-2017 LK06_RS15935 6d0f1fde534ea3df8a613cad093423e4 785 PRINTS PR01806 Virulence factor MviN signature 298 314 3.6E-18 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS15935 6d0f1fde534ea3df8a613cad093423e4 785 PRINTS PR01806 Virulence factor MviN signature 402 423 3.6E-18 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS15935 6d0f1fde534ea3df8a613cad093423e4 785 PRINTS PR01806 Virulence factor MviN signature 378 402 3.6E-18 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS15935 6d0f1fde534ea3df8a613cad093423e4 785 PRINTS PR01806 Virulence factor MviN signature 620 639 3.6E-18 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS15935 6d0f1fde534ea3df8a613cad093423e4 785 PRINTS PR01806 Virulence factor MviN signature 676 693 3.6E-18 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS15935 6d0f1fde534ea3df8a613cad093423e4 785 PRINTS PR01806 Virulence factor MviN signature 279 298 3.6E-18 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS15935 6d0f1fde534ea3df8a613cad093423e4 785 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 249 776 1.9E-152 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS15935 6d0f1fde534ea3df8a613cad093423e4 785 Pfam PF03023 MviN-like protein 274 751 1.2E-133 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ LK06_RS19140 1f32c2c275433a59cb67194a540a4cf3 412 Pfam PF02687 FtsX-like permease family 293 405 1.1E-23 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 LK06_RS19140 1f32c2c275433a59cb67194a540a4cf3 412 Pfam PF12704 MacB-like periplasmic core domain 42 253 6.8E-14 T 06-07-2017 IPR025857 MacB-like periplasmic core domain LK06_RS09015 51d7e76d1a992c4c6a11c30eef92d9f3 505 Pfam PF13556 PucR C-terminal helix-turn-helix domain 442 500 9.8E-20 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS14925 8431399b0698be580c1d5673f937c2d8 129 Pfam PF05331 Protein of unknown function (DUF742) 13 121 1.2E-26 T 06-07-2017 IPR007995 Protein of unknown function DUF742 LK06_RS13890 e47a6888ddd2100fc0c02704440bf28e 169 Pfam PF14016 Protein of unknown function (DUF4232) 33 165 1.4E-19 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 LK06_RS13205 04800ea8c0867ab84d08b8127664f3b7 73 Pfam PF08889 WbqC-like protein family 6 71 1.2E-8 T 06-07-2017 IPR014985 WbqC-like protein family LK06_RS06695 8635f3940288715840846cc367e10191 333 Pfam PF03741 Integral membrane protein TerC family 68 274 1.9E-53 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 LK06_RS06695 8635f3940288715840846cc367e10191 333 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 310 2.7E-115 T 06-07-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 LK06_RS03645 9092cf4976b575afab64509a377a8374 287 Pfam PF05949 Bacterial protein of unknown function (DUF881) 150 282 2.1E-40 T 06-07-2017 IPR010273 Protein of unknown function DUF881 LK06_RS01465 043552e3dba9d0e843f5b26647cd4f84 151 Pfam PF13463 Winged helix DNA-binding domain 36 101 3.2E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LK06_RS01465 043552e3dba9d0e843f5b26647cd4f84 151 SUPERFAMILY SSF46785 15 141 2.58E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS01465 043552e3dba9d0e843f5b26647cd4f84 151 Gene3D G3DSA:1.10.10.10 19 141 4.6E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS14155 2ef80c0ca90fc0ef4eec24a813fc4022 53 Pfam PF13783 Domain of unknown function (DUF4177) 4 49 1.5E-6 T 06-07-2017 IPR025234 Protein of unknown function DUF4177 LK06_RS11370 1815adc949d6bbb9e530cdbef8134851 120 Gene3D G3DSA:1.10.287.1060 15 105 1.9E-4 T 06-07-2017 LK06_RS20950 d7572f50ae9f130e2da4f291f478b7f0 511 SUPERFAMILY SSF103473 468 498 1.57E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS20950 d7572f50ae9f130e2da4f291f478b7f0 511 SUPERFAMILY SSF103473 239 410 1.57E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS20950 d7572f50ae9f130e2da4f291f478b7f0 511 SUPERFAMILY SSF103473 5 194 1.57E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS20950 d7572f50ae9f130e2da4f291f478b7f0 511 Gene3D G3DSA:1.20.1250.20 261 416 3.8E-17 T 06-07-2017 LK06_RS20950 d7572f50ae9f130e2da4f291f478b7f0 511 Gene3D G3DSA:1.20.1250.20 475 502 3.8E-17 T 06-07-2017 LK06_RS20950 d7572f50ae9f130e2da4f291f478b7f0 511 Gene3D G3DSA:1.20.1250.20 14 187 1.4E-22 T 06-07-2017 LK06_RS20950 d7572f50ae9f130e2da4f291f478b7f0 511 Pfam PF07690 Major Facilitator Superfamily 22 401 1.6E-32 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LK06_RS12780 7c180f7104018e193a0fbfad9ff47d99 265 Pfam PF01061 ABC-2 type transporter 25 202 3.7E-9 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LK06_RS04720 9a0911eeedd58a0762fc5d3a4b4598d1 120 Pfam PF04138 GtrA-like protein 8 117 7.4E-20 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 LK06_RS30325 0eb2593e99f865ef3c04a1a4da64055b 125 Pfam PF02641 Uncharacterized ACR, COG1993 10 105 4.9E-41 T 06-07-2017 IPR003793 Domain of unknown function DUF190 LK06_RS30325 0eb2593e99f865ef3c04a1a4da64055b 125 Gene3D G3DSA:3.30.70.120 4 113 1.5E-47 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal LK06_RS30325 0eb2593e99f865ef3c04a1a4da64055b 125 SUPERFAMILY SSF54913 8 106 2.45E-35 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta LK06_RS04380 7367c2b6431953a73bf917c06a14cc8b 70 Pfam PF13619 KTSC domain 8 64 1.4E-23 T 06-07-2017 IPR025309 KTSC domain LK06_RS29895 1ab3aac91f812d39e8fd8809c6169dc3 265 Pfam PF13515 Fusaric acid resistance protein-like 42 152 2.9E-15 T 06-07-2017 LK06_RS29155 2532eae97808206627495748b083bd5d 234 Pfam PF08388 Group II intron, maturase-specific domain 121 181 1.0E-14 T 06-07-2017 IPR013597 Group II intron, maturase-specific LK06_RS00040 cc9693c1a39675dc3b9482924318c06e 377 Pfam PF02653 Branched-chain amino acid transport system / permease component 66 344 1.1E-28 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 LK06_RS14250 cfa020536bbc18d0d5c40243f78261ae 297 PIRSF PIRSF030850 2 289 6.6E-54 T 06-07-2017 IPR011396 Uncharacterised conserved protein UCP030850 LK06_RS14250 cfa020536bbc18d0d5c40243f78261ae 297 Pfam PF13391 HNH endonuclease 180 233 3.5E-9 T 06-07-2017 IPR003615 HNH nuclease LK06_RS23410 36e3b95ba0db934ca558e9940a39ed07 257 Pfam PF12679 ABC-2 family transporter protein 69 255 2.4E-6 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 LK06_RS31995 2839e7acb95d6fba62887969bf692017 195 SUPERFAMILY SSF46955 76 120 8.7E-5 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS19560 014570399bbd801e83b55191b4cfacf8 310 Pfam PF12183 Restriction endonuclease NotI 21 239 3.2E-7 T 06-07-2017 IPR022009 Restriction endonuclease, type II, NotI LK06_RS27850 b3b2be803c56694260074acc0b32933e 525 Pfam PF07905 Purine catabolism regulatory protein-like family 22 141 5.5E-32 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain LK06_RS27850 b3b2be803c56694260074acc0b32933e 525 Pfam PF13556 PucR C-terminal helix-turn-helix domain 461 519 3.3E-14 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS27850 b3b2be803c56694260074acc0b32933e 525 Gene3D G3DSA:1.10.10.60 463 497 7.1E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 LK06_RS28825 a080f27a5890b5b7f143956813321c71 123 Gene3D G3DSA:1.10.10.10 61 106 3.4E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain LK06_RS28825 a080f27a5890b5b7f143956813321c71 123 Pfam PF05331 Protein of unknown function (DUF742) 13 122 1.2E-37 T 06-07-2017 IPR007995 Protein of unknown function DUF742 LK06_RS26765 502df07b19f0f5dc6dff2cc3df2c631f 199 Pfam PF03029 Conserved hypothetical ATP binding protein 27 165 2.8E-19 T 06-07-2017 IPR004130 GPN-loop GTPase LK06_RS26765 502df07b19f0f5dc6dff2cc3df2c631f 199 Gene3D G3DSA:3.40.50.300 22 196 2.9E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS26765 502df07b19f0f5dc6dff2cc3df2c631f 199 SUPERFAMILY SSF52540 20 196 2.01E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS31935 e4ddb55c1b7e262f26786aa1d6114e4a 505 Gene3D G3DSA:3.40.109.10 407 492 1.8E-7 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS31935 e4ddb55c1b7e262f26786aa1d6114e4a 505 SUPERFAMILY SSF55469 412 494 1.96E-8 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LK06_RS18650 0b6905023d36a944a679808de3e506a8 579 Pfam PF07287 Protein of unknown function (DUF1446) 6 348 1.9E-123 T 06-07-2017 IPR010839 Protein of unknown function DUF1446 LK06_RS10430 f51191bfe2fff07cd0f81a9e8e7593b7 463 Pfam PF13520 Amino acid permease 25 419 2.4E-33 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS10430 f51191bfe2fff07cd0f81a9e8e7593b7 463 PIRSF PIRSF006060 8 457 1.7E-53 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 LK06_RS02020 b3f9e5c59151eb01dfad0511f5a30724 145 Pfam PF13358 DDE superfamily endonuclease 30 104 1.4E-14 T 06-07-2017 LK06_RS14340 c2bd4c970235ce39c435652e2f9b21a0 210 Pfam PF01914 MarC family integral membrane protein 6 206 3.2E-30 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 LK06_RS22440 3dc313baf2789c04e856136f0b4ed6a8 90 Pfam PF11755 Protein of unknown function (DUF3311) 22 79 1.8E-24 T 06-07-2017 IPR021741 Protein of unknown function DUF3311 LK06_RS21280 038e9361fdebda6fd4a9bc51adfbe749 314 Pfam PF00482 Type II secretion system (T2SS), protein F 147 270 5.8E-18 T 06-07-2017 IPR018076 Type II secretion system F domain LK06_RS13345 812433a23ddf62d947f7b23aad33b7f1 409 Pfam PF10935 Protein of unknown function (DUF2637) 8 161 1.3E-41 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 LK06_RS23055 8d99a7ba7a7aa5d789cd03a57d69a00f 302 SUPERFAMILY SSF52540 29 93 3.72E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23055 8d99a7ba7a7aa5d789cd03a57d69a00f 302 SUPERFAMILY SSF52540 123 254 3.72E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS23055 8d99a7ba7a7aa5d789cd03a57d69a00f 302 Gene3D G3DSA:3.40.50.300 29 285 3.5E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase LK06_RS09770 0f5448234a01182663eea062d7ff1e55 61 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 52 1.1E-8 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 LK06_RS09770 0f5448234a01182663eea062d7ff1e55 61 Pfam PF12728 Helix-turn-helix domain 6 54 4.3E-11 T 06-07-2017 LK06_RS19410 3b23b9f6a7a06480580a6938dbdfd97b 56 Pfam PF13408 Recombinase zinc beta ribbon domain 13 55 1.1E-6 T 06-07-2017 IPR025827 Recombinase zinc beta ribbon domain LK06_RS27300 d4b3d49373e38b95188245b3896b1454 140 Pfam PF15868 Transcription activator MBF2 58 136 5.2E-9 T 06-07-2017 IPR031734 Transcription activator MBF2 LK06_RS10920 d70399597ac4b8a947aa431e7634b143 243 PIRSF PIRSF015736 3 239 1.2E-47 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase LK06_RS24835 1a34064cd6ad54f4da629851c030e6c4 591 Gene3D G3DSA:1.10.287.1060 65 144 5.8E-4 T 06-07-2017 LK06_RS03205 5e706bbd8a1f9f6e39e4ae59f8baf8a0 141 Gene3D G3DSA:3.10.450.50 3 130 6.4E-49 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS03205 5e706bbd8a1f9f6e39e4ae59f8baf8a0 141 SUPERFAMILY SSF54427 7 129 1.36E-31 T 06-07-2017 IPR032710 NTF2-like domain LK06_RS03205 5e706bbd8a1f9f6e39e4ae59f8baf8a0 141 Pfam PF12680 SnoaL-like domain 14 117 1.0E-10 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain LK06_RS28115 2afe4bbe244bc956acf211adba505c62 129 Pfam PF11387 Protein of unknown function (DUF2795) 76 113 3.0E-7 T 06-07-2017 IPR021527 Protein of unknown function DUF2795 LK06_RS30685 23c71dc7f8a726fa16070bdad6f80d22 54 Gene3D G3DSA:3.40.630.30 1 45 2.8E-4 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS13005 834020e61b70b3a0adc137cbd06edc9f 30 Pfam PF13358 DDE superfamily endonuclease 2 27 1.3E-7 T 06-07-2017 LK06_RS19695 60751c6bc9469eeb3cae440ef34dc74e 133 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 26 48 - T 06-07-2017 IPR007087 Zinc finger, C2H2 GO:0046872 LK06_RS27360 1888598cfd0675374cbc44ae1abedfba 188 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 7 111 1.6E-11 T 06-07-2017 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain LK06_RS24555 013bfcb754119e61f61d5a3eb2121ad7 135 Gene3D G3DSA:3.10.180.10 3 131 2.4E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS24555 013bfcb754119e61f61d5a3eb2121ad7 135 SUPERFAMILY SSF54593 4 131 3.16E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LK06_RS03435 7b2358f348bddf6e38dd6e5fd6c2babd 175 Pfam PF15589 Immunity protein 21 1 157 1.8E-46 T 06-07-2017 IPR028961 Immunity protein 21 LK06_RS14780 67c974a28fa2eae586b77c02fb74b1d4 324 Pfam PF04893 Yip1 domain 157 315 8.1E-15 T 06-07-2017 IPR006977 Yip1 domain GO:0016020 LK06_RS07980 f5a6b2c3708ac6730ba49f9eedb68e6a 456 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 82 424 1.3E-42 T 06-07-2017 IPR003776 YcaO-like domain LK06_RS25325 e7a437164e119ee0df30a987449f88aa 530 Pfam PF00474 Sodium:solute symporter family 38 453 3.6E-79 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 LK06_RS10465 9ec139bdbcf287724db3c7a326b49314 66 SUPERFAMILY SSF46955 5 57 4.07E-8 T 06-07-2017 IPR009061 Putative DNA-binding domain LK06_RS10465 9ec139bdbcf287724db3c7a326b49314 66 Gene3D G3DSA:1.10.1660.10 5 46 2.4E-5 T 06-07-2017 LK06_RS23595 ae9a157a968d2099836db0696192018e 254 Pfam PF09900 Predicted membrane protein (DUF2127) 75 221 1.2E-43 T 06-07-2017 IPR021125 Protein of unknown function DUF2127 LK06_RS03485 13962011be5299d15b0c8f80781d387f 196 SUPERFAMILY SSF140453 118 186 6.41E-5 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like LK06_RS21285 527e294c7bdbc4130169704708ef6ca7 295 Pfam PF00482 Type II secretion system (T2SS), protein F 152 277 2.1E-19 T 06-07-2017 IPR018076 Type II secretion system F domain LK06_RS04980 5b74ce3f39b47ed0fc505306917d6a4b 325 Pfam PF13280 WYL domain 156 322 3.6E-31 T 06-07-2017 IPR026881 WYL domain LK06_RS16725 223576948a0a29e8bdb7379727a43edc 225 Pfam PF03729 Short repeat of unknown function (DUF308) 113 182 3.8E-10 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane LK06_RS16725 223576948a0a29e8bdb7379727a43edc 225 Pfam PF03729 Short repeat of unknown function (DUF308) 56 126 1.1E-14 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane LK06_RS16725 223576948a0a29e8bdb7379727a43edc 225 Pfam PF03729 Short repeat of unknown function (DUF308) 170 218 1.2E-7 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane LK06_RS16725 223576948a0a29e8bdb7379727a43edc 225 SUPERFAMILY SSF103473 42 203 8.11E-5 T 06-07-2017 IPR020846 Major facilitator superfamily domain LK06_RS27285 dd3f4cb09bb1730972af0b69d825f8a7 405 Pfam PF01474 Class-II DAHP synthetase family 3 161 2.8E-61 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 LK06_RS27285 dd3f4cb09bb1730972af0b69d825f8a7 405 Pfam PF01474 Class-II DAHP synthetase family 162 376 2.2E-99 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 LK06_RS27285 dd3f4cb09bb1730972af0b69d825f8a7 405 SUPERFAMILY SSF51569 2 379 2.45E-160 T 06-07-2017 LK06_RS29810 c900cb21e3b0311ac6a6cd16e7c14274 509 Pfam PF13515 Fusaric acid resistance protein-like 198 323 2.2E-14 T 06-07-2017 LK06_RS22765 ee73058bdc619bb583334a0f627ebae9 155 Pfam PF08239 Bacterial SH3 domain 88 145 1.3E-7 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type LK06_RS08770 987b9da7c95f6161697c2731431c7238 379 Pfam PF04332 Protein of unknown function (DUF475) 44 361 4.0E-142 T 06-07-2017 IPR007427 Protein of unknown function DUF475 LK06_RS24225 d6f0009d6049b45cd64fe44b8dd0dea7 172 Pfam PF12028 Protein of unknown function (DUF3515) 19 166 1.7E-22 T 06-07-2017 IPR021903 Protein of unknown function DUF3515 LK06_RS05615 ccac0b384bc2f7dee0aa5b06a6f3539a 71 Pfam PF11720 Peptidase inhibitor I78 family 17 65 3.4E-7 T 06-07-2017 IPR021719 Proteinase inhibitor I78 LK06_RS10905 4ba6370dfcf6488d3f87f03fa5b5bde8 419 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 70 345 8.3E-58 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 LK06_RS10905 4ba6370dfcf6488d3f87f03fa5b5bde8 419 Gene3D G3DSA:3.40.390.10 207 265 6.2E-5 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 LK06_RS07045 f520c647787e902492b84c4740bc8351 243 Pfam PF01988 VIT family 28 235 4.7E-64 T 06-07-2017 IPR008217 Ccc1 family LK06_RS01760 c8064dc132f7974d23edd905a532390f 257 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 224 243 7.3E-8 T 06-07-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 LK06_RS12655 9f97c8fd49496fee1a052ce323ef745f 205 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 31 173 4.4E-31 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS15195 e83f19e6900724012031de5f3ff15234 236 Pfam PF14219 Domain of unknown function (DUF4328) 74 209 1.2E-25 T 06-07-2017 IPR025565 Domain of unknown function DUF4328 LK06_RS30935 f85af9e2cf079a925df9240567894f2b 740 Pfam PF04632 Fusaric acid resistance protein family 412 724 2.8E-17 T 06-07-2017 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 LK06_RS29515 6736ef1321e9d85a17969440dbcc9d76 242 Pfam PF02535 ZIP Zinc transporter 90 238 5.6E-28 T 06-07-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 LK06_RS29515 6736ef1321e9d85a17969440dbcc9d76 242 Pfam PF02535 ZIP Zinc transporter 5 88 8.6E-9 T 06-07-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 LK06_RS01715 bd6fafcb6feee0a3b5dd1930d24c9843 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 294 1.6E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS01715 bd6fafcb6feee0a3b5dd1930d24c9843 301 SUPERFAMILY SSF161098 35 301 1.7E-66 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS01715 bd6fafcb6feee0a3b5dd1930d24c9843 301 Gene3D G3DSA:1.10.3720.10 34 288 8.6E-61 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 LK06_RS31350 ed52c5d6f5968abe06ad6ceed05cdec6 250 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 24 241 3.2E-46 T 06-07-2017 IPR015402 Protein of unknown function DUF1980 LK06_RS01620 0dfefcbfb12e00600cda2cee243c6d43 254 Pfam PF14023 Protein of unknown function (DUF4239) 49 246 1.1E-21 T 06-07-2017 IPR025333 Protein of unknown function DUF4239 LK06_RS22515 e403375c1250a2dc6bd595700b711031 110 SUPERFAMILY SSF56399 7 108 2.7E-22 T 06-07-2017 LK06_RS22515 e403375c1250a2dc6bd595700b711031 110 Pfam PF06108 Protein of unknown function (DUF952) 11 106 1.1E-24 T 06-07-2017 IPR009297 Protein of unknown function DUF952 LK06_RS15780 540e15275369cae9cbc56d24eb3a85ac 62 Pfam PF05122 Mobile element transfer protein 12 61 8.1E-28 T 06-07-2017 IPR007806 Mobile element transfer LK06_RS16420 b08623aa2150d9e1a4c248339a326b01 63 Pfam PF05122 Mobile element transfer protein 12 60 1.6E-30 T 06-07-2017 IPR007806 Mobile element transfer LK06_RS30360 40eed4c3e514ccbf7611a7473081b5d7 468 Pfam PF09594 Protein of unknown function (DUF2029) 145 380 4.0E-7 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 LK06_RS29445 7b028b2a8e1664ef6b9429409d2b9131 137 SUPERFAMILY SSF51182 8 131 1.61E-27 T 06-07-2017 IPR011051 RmlC-like cupin domain LK06_RS29445 7b028b2a8e1664ef6b9429409d2b9131 137 Gene3D G3DSA:2.60.120.10 5 130 4.1E-27 T 06-07-2017 IPR014710 RmlC-like jelly roll fold LK06_RS29445 7b028b2a8e1664ef6b9429409d2b9131 137 Pfam PF07883 Cupin domain 39 97 5.7E-9 T 06-07-2017 IPR013096 Cupin 2, conserved barrel LK06_RS30925 288cf5b1da54b292b6be7ba11e3e554f 204 Pfam PF01810 LysE type translocator 16 201 2.6E-34 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 LK06_RS28465 70f3d1c8a5862ff7d5cb977063858af1 224 Gene3D G3DSA:3.30.450.20 25 64 1.5E-4 T 06-07-2017 LK06_RS21165 de5490e36a7fa0efd1178dfbdada9331 237 Pfam PF03006 Haemolysin-III related 29 226 1.9E-44 T 06-07-2017 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 LK06_RS22745 b668c47021c2599acafba674b73f7bcf 312 SUPERFAMILY SSF47240 38 228 1.18E-12 T 06-07-2017 IPR009078 Ferritin-like superfamily LK06_RS22745 b668c47021c2599acafba674b73f7bcf 312 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 21 295 1.2E-96 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF LK06_RS30575 3da174780d1d78364a7af0d462509fc1 161 Gene3D G3DSA:3.30.428.10 16 147 8.9E-18 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS30575 3da174780d1d78364a7af0d462509fc1 161 SUPERFAMILY SSF54197 17 154 6.07E-15 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 LK06_RS04610 a1240a882158e2150b50e55886761132 165 SUPERFAMILY SSF55729 1 143 7.43E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS04610 a1240a882158e2150b50e55886761132 165 Gene3D G3DSA:3.40.630.30 2 158 2.7E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase LK06_RS04610 a1240a882158e2150b50e55886761132 165 Pfam PF00583 Acetyltransferase (GNAT) family 61 138 5.0E-16 T 06-07-2017 IPR000182 GNAT domain GO:0008080 LK06_RS25970 e9b3ccfe75cf70ec22184e92e00df7e1 249 Pfam PF10099 Anti-sigma-K factor rskA 58 244 1.4E-31 T 06-07-2017 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 LK06_RS26695 af21ed874c904fd5bd89d6b795b931e7 496 Pfam PF00916 Sulfate permease family 18 385 1.0E-55 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 LK06_RS12680 4f5b3b3c1ea1d07a3316c4edc20c8172 139 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 39 138 2.2E-29 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LK06_RS26470 c42b41661b196cdfbee4be4c064255d3 146 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 6 37 2.6E-4 T 06-07-2017 IPR006530 YD repeat LK06_RS26470 c42b41661b196cdfbee4be4c064255d3 146 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 104 130 0.0014 T 06-07-2017 IPR006530 YD repeat LK06_RS26470 c42b41661b196cdfbee4be4c064255d3 146 Pfam PF05593 RHS Repeat 111 146 5.7E-9 T 06-07-2017 IPR031325 RHS repeat LK06_RS26470 c42b41661b196cdfbee4be4c064255d3 146 Pfam PF05593 RHS Repeat 6 37 3.3E-8 T 06-07-2017 IPR031325 RHS repeat LK06_RS05420 112ca954d4e4a48fae427d39e70d9568 513 Pfam PF14224 Domain of unknown function (DUF4331) 44 442 2.1E-156 T 06-07-2017 IPR025566 Protein of unknown function DUF4331 LK06_RS01780 71dfb561ea23645760d80a22a2443d45 88 PRINTS PR01217 Proline rich extensin signature 1 17 1.6E-11 T 06-07-2017 LK06_RS01780 71dfb561ea23645760d80a22a2443d45 88 PRINTS PR01217 Proline rich extensin signature 43 64 1.6E-11 T 06-07-2017 LK06_RS01780 71dfb561ea23645760d80a22a2443d45 88 PRINTS PR01217 Proline rich extensin signature 21 33 1.6E-11 T 06-07-2017 LK06_RS06865 7dd80a6b44e7c141203106100e2938dc 331 Pfam PF11271 Protein of unknown function (DUF3068) 5 306 6.1E-76 T 06-07-2017 IPR021424 Protein of unknown function DUF3068 LK06_RS14890 c798bf8e32ea4d4f61558a8159cca8d9 437 Pfam PF14240 YHYH protein 262 354 5.3E-13 T 06-07-2017 IPR025924 YHYH domain LK06_RS17280 976e7d416077f90c4c2c2c47f99cd9f5 463 Pfam PF13367 Protease prsW family 117 317 8.8E-51 T 06-07-2017 IPR026898 Protease PrsW GO:0008233 LK06_RS14040 737f1c70f65587a16681ff47df833f17 59 Pfam PF14029 Protein of unknown function (DUF4244) 4 56 2.8E-24 T 06-07-2017 IPR025338 Protein of unknown function DUF4244 LK06_RS19320 0af1e6036090582257ae80a621196c2f 412 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 36 388 1.3E-91 T 06-07-2017 IPR010640 Low temperature requirement A LK06_RS14330 dfbe6226030fbbf460be294350b3c600 163 Pfam PF17197 Domain of unknown function (DUF5134) 43 148 3.7E-11 T 06-07-2017 IPR033458 Protein of unknown function DUF5134 LK06_RS10400 0b6e4009f6aa082780bcd18858f3fa8e 75 Pfam PF03777 Small secreted domain (DUF320) 19 74 1.5E-30 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species LK06_RS13385 17f9ad88b1d425bbfa7f2d7f7bb2d013 272 Pfam PF14062 Domain of unknown function (DUF4253) 164 272 5.7E-39 T 06-07-2017 IPR025349 Domain of unknown function DUF4253 LK06_RS20690 bd77a838b9c9a571d08a7266c3f8b056 375 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 339 2.6E-40 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 LK06_RS29885 c4747640da8f61639a2fc92677db203d 311 Gene3D G3DSA:3.30.2010.10 160 196 1.9E-5 T 06-07-2017 LK06_RS09120 623736e7dc5deed3cbb25762655a25c8 73 Pfam PF14657 AP2-like DNA-binding integrase domain 31 73 1.7E-9 T 06-07-2017 IPR028259 AP2-like integrase, N-terminal domain LK06_RS15280 36f3656d06ed8ee30e997f4c808cfab8 646 Pfam PF13515 Fusaric acid resistance protein-like 364 484 6.1E-21 T 06-07-2017 LK06_RS12850 0ec0878cb2ecff9e4fa6d4b3f5aef67e 182 Gene3D G3DSA:3.90.470.20 33 100 3.5E-4 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 LK06_RS25840 df238c54445d4258ed6656c6cca41631 412 Pfam PF04230 Polysaccharide pyruvyl transferase 21 328 1.1E-24 T 06-07-2017 IPR007345 Polysaccharide pyruvyl transferase LK06_RS14210 444e2a876dd442a4146fce2e0c2573f2 332 Pfam PF13808 DDE_Tnp_1-associated 1 64 1.4E-8 T 06-07-2017 IPR032806 H repeat-associated protein, N-terminal LK06_RS01505 007b584ad61f49d5447df520b10f4f0b 72 Gene3D G3DSA:2.40.50.140 4 57 4.6E-5 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold LK06_RS18515 cf6328ab6d7cc8d920fa66326417cc71 47 Pfam PF04149 Domain of unknown function (DUF397) 1 42 8.3E-10 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS07335 160161fd196adbe3ce8d8a24c236bda8 216 Pfam PF04977 Septum formation initiator 77 124 5.8E-7 T 06-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 LK06_RS25155 3f01a3b4b64b850348c19dda4982d4d9 378 Gene3D G3DSA:2.40.10.10 142 245 5.5E-7 T 06-07-2017 LK06_RS25155 3f01a3b4b64b850348c19dda4982d4d9 378 SUPERFAMILY SSF50494 122 349 1.23E-15 T 06-07-2017 IPR009003 Peptidase S1, PA clan LK06_RS01565 2046b0b7015613b38a43198a4cdef994 62 Pfam PF14013 MT0933-like antitoxin protein 4 51 6.5E-15 T 06-07-2017 IPR028037 Antitoxin Rv0909/MT0933 LK06_RS00225 99e0b53e9de8d91440ec631d86b406e9 76 Gene3D G3DSA:3.40.50.10580 3 60 9.6E-4 T 06-07-2017 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 LK06_RS21230 668e23f5176d77182805cae6418316bd 61 Pfam PF04149 Domain of unknown function (DUF397) 6 59 1.1E-20 T 06-07-2017 IPR007278 Domain of unknown function DUF397 LK06_RS02055 a26318d3016d2120ac73dd8b493976fd 355 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 73 342 1.2E-25 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD LK06_RS29115 5df2728ee43516c3c5e8e146ecf6f047 224 Pfam PF01609 Transposase DDE domain 74 191 7.1E-7 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 LK06_RS25820 36cd42dadd2a450421072c51a955e4a3 447 Pfam PF02945 Recombination endonuclease VII 249 285 5.0E-8 T 06-07-2017 IPR004211 Recombination endonuclease VII LK06_RS25820 36cd42dadd2a450421072c51a955e4a3 447 SUPERFAMILY SSF54060 249 305 5.77E-9 T 06-07-2017 LK06_RS23160 b3fd4254bb3665c0b84d1e587ff25561 128 Gene3D G3DSA:3.40.50.1390 28 75 2.7E-4 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 LK06_RS20750 be78261710dd7bc96c8024812b493431 66 Pfam PF04024 PspC domain 4 58 4.8E-17 T 06-07-2017 IPR007168 Phage shock protein, PspC, N-terminal LK06_RS20310 bf3f2040f64fbc2f1d75ed50bf43c30a 451 Pfam PF04434 SWIM zinc finger 72 90 2.8E-5 T 06-07-2017 IPR007527 Zinc finger, SWIM-type GO:0008270 LK06_RS22715 befee717131107baa49a27fe9b22e59b 154 Pfam PF05331 Protein of unknown function (DUF742) 16 154 1.3E-40 T 06-07-2017 IPR007995 Protein of unknown function DUF742 LK06_RS13075 5362a70d24757778cae1b9f99044402b 128 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 59 2.8E-11 T 06-07-2017 IPR027379 Cardiolipin synthase N-terminal LK06_RS10420 fe4e273b6984ff9ddf40c75168519070 287 Pfam PF12679 ABC-2 family transporter protein 25 285 3.6E-10 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 LK06_RS19020 a74064232d05287fe28a6ba194b0fadc 178 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 22 169 2.4E-56 T 06-07-2017 IPR018681 Protein of unknown function DUF2165, transmembrane LK06_RS31355 baebb1dd8a523e49d3e1b0247e35bcea 88 Pfam PF04226 Transglycosylase associated protein 33 83 9.9E-10 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 LK06_RS03560 fad38bb76e28b2e5ec72e4b90cc4d89f 266 Pfam PF02517 CAAX protease self-immunity 159 247 3.3E-15 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 LK06_RS21755 d573ba42c2587e6e7d8f7c15b7787ef0 66 Pfam PF05036 Sporulation related domain 14 46 9.0E-5 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 LK06_RS21755 d573ba42c2587e6e7d8f7c15b7787ef0 66 Gene3D G3DSA:3.30.70.1070 16 51 3.1E-4 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 LK06_RS26615 0d907058760cfa7ed91a7e31ae5337a4 223 Pfam PF11452 Protein of unknown function (DUF3000) 31 204 1.1E-70 T 06-07-2017 IPR021555 Protein of unknown function DUF3000 LK06_RS12050 ce75188f6ab82995ac78edc715022c6f 254 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 214 248 9.8E-6 T 06-07-2017 IPR019931 LPXTG cell wall anchor domain LK06_RS17530 0500e4b958bd21d891301fb1f1bd5b6e 114 Pfam PF02583 Metal-sensitive transcriptional repressor 29 109 3.1E-31 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 LK06_RS03845 e8a6d91ec8de54fc9e0ad7ce3237199f 124 Pfam PF13397 RNA polymerase-binding protein 4 107 6.5E-42 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 LK06_RS03845 e8a6d91ec8de54fc9e0ad7ce3237199f 124 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 120 26.533 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 LK06_RS31820 1e528bae80b61dc9455a9303ee449dc2 245 Pfam PF13349 Putative adhesin 106 243 1.5E-11 T 06-07-2017 IPR025164 Putative adhesin LK06_RS05480 1752074cc11c3714a628f7f24951f804 256 SUPERFAMILY SSF117396 3 236 4.97E-72 T 06-07-2017 IPR002763 Protein of unknown function DUF72 LK06_RS05480 1752074cc11c3714a628f7f24951f804 256 Pfam PF01904 Protein of unknown function DUF72 20 236 1.7E-55 T 06-07-2017 IPR002763 Protein of unknown function DUF72 LK06_RS05480 1752074cc11c3714a628f7f24951f804 256 Gene3D G3DSA:3.20.20.410 3 236 1.2E-70 T 06-07-2017 IPR002763 Protein of unknown function DUF72 LK06_RS05135 f2ab6c2500cc5089dd969fedcbd19f44 274 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 22 274 2.4E-111 T 06-07-2017 IPR022292 Conserved hypothetical protein CHP03843 LK06_RS15175 811e24b8cd56821507972bde29558814 353 Pfam PF13556 PucR C-terminal helix-turn-helix domain 284 340 6.6E-16 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain LK06_RS31240 9ae09f6af2598770f89f9e39c716153d 143 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 3 129 5.9E-32 T 06-07-2017 IPR018727 Protein of unknown function DUF2267 LK06_RS21850 df6d0fcb36b9a8827ae8fe5d704f399e 424 Gene3D G3DSA:3.30.2010.10 133 208 5.7E-6 T 06-07-2017 LK06_RS14410 1a3a713ea829386b5c8c096b284a9a88 248 Pfam PF01925 Sulfite exporter TauE/SafE 8 242 3.2E-45 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 LK06_RS23425 280d6f3935b16892642521a5cbe662d9 1370 Gene3D G3DSA:1.20.120.20 864 1010 4.2E-5 T 06-07-2017 LK06_RS08310 786515f494769fd02cdb8a386e3b7efb 244 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 38 212 2.8E-27 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal LK06_RS08310 786515f494769fd02cdb8a386e3b7efb 244 SMART SM00943 36 217 2.7E-38 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal LK06_RS09255 18f228d3a48c5f016fa17c56439f4c2c 495 SUPERFAMILY SSF48208 39 459 8.26E-64 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 LK06_RS00350 2d13ccc02050440cfc7eb8f429c2acc4 99 Pfam PF03640 Secreted repeat of unknown function 67 97 4.5E-8 T 06-07-2017 IPR005297 Lipoprotein repeat LK06_RS25170 805f6ec81fc8e272bcc0ed334e569498 243 Pfam PF13628 Domain of unknown function (DUF4142) 54 187 2.5E-13 T 06-07-2017 IPR025419 Domain of unknown function DUF4142 LK06_RS25470 99e3e1e70ba0f336d136c4d7d53c7d84 154 Pfam PF11292 Protein of unknown function (DUF3093) 8 146 3.6E-44 T 06-07-2017 IPR021443 Protein of unknown function DUF3093 LK06_RS18160 6a4828c6252a067de978b6702d19e161 196 SUPERFAMILY SSF144091 5 180 6.02E-6 T 06-07-2017 LK06_RS13835 80fbb1da26d2cd29fa3ac1ef3cfcec9d 334 Pfam PF09335 SNARE associated Golgi protein 41 168 1.1E-22 T 06-07-2017 IPR032816 SNARE associated Golgi protein LK06_RS15150 9217ff0bbe4c5bfefd4d8f374ae6e3aa 420 Pfam PF00999 Sodium/hydrogen exchanger family 10 381 1.1E-44 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 LK06_RS32180 ee1e35313e025638cafe434898ad41dd 196 Gene3D G3DSA:1.25.40.10 9 39 2.2E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS32180 ee1e35313e025638cafe434898ad41dd 196 Gene3D G3DSA:1.25.40.10 72 167 2.2E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 LK06_RS15940 fcc09e5ba30672d8c9b1a65a5ae9d45d 790 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 75 - T 06-07-2017 IPR010916 TonB box, conserved site