locus-tag	class	description
FGW37_RS00085	COG4221	oxidoreductase activity
FGW37_RS00115	COG1595	DNA-templated transcription, initiation
FGW37_RS00120	COG0438	transferase activity, transferring glycosyl groups
FGW37_RS00125	COG0745	RESPONSE REGULATOR receiver
FGW37_RS00130	COG2205	protein histidine kinase activity
FGW37_RS00150	COG1131	(ABC) transporter
FGW37_RS00180	COG0604	alcohol dehydrogenase
FGW37_RS00260	COG2124	cytochrome p450
FGW37_RS00265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGW37_RS00290	COG2409	Drug exporters of the RND superfamily
FGW37_RS00305	COG3152	Membrane
FGW37_RS00380	COG3629	intracellular signal transduction
FGW37_RS00380	COG3903	Transcriptional regulator
FGW37_RS00390	COG0662	Cupin 2, conserved barrel domain protein
FGW37_RS00445	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGW37_RS00450	COG2226	methyltransferase
FGW37_RS00460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGW37_RS00480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS00500	COG1132	(ABC) transporter
FGW37_RS00620	COG2814	Major facilitator Superfamily
FGW37_RS00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGW37_RS00640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGW37_RS00650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FGW37_RS00685	COG2770	Histidine kinase
FGW37_RS00685	COG2208	phosphoserine phosphatase activity
FGW37_RS00700	COG4552	Acetyltransferase involved in intracellular survival and related
FGW37_RS00730	COG0181	hydroxymethylbilane synthase activity
FGW37_RS00750	COG2318	DinB family
FGW37_RS00760	COG1473	amidohydrolase
FGW37_RS00765	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FGW37_RS00785	COG0596	Alpha beta hydrolase
FGW37_RS00790	COG0326	Molecular chaperone. Has ATPase activity
FGW37_RS00800	COG3795	YCII-related domain
FGW37_RS00810	COG0667	Aldo Keto reductase
FGW37_RS00860	COG3629	intracellular signal transduction
FGW37_RS00895	COG1131	(ABC) transporter
FGW37_RS00915	COG1473	amidohydrolase
FGW37_RS00950	COG4221	oxidoreductase activity
FGW37_RS00955	COG1309	transcriptional regulator
FGW37_RS00960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGW37_RS00960	COG0515	serine threonine protein kinase
FGW37_RS00965	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGW37_RS00965	COG0515	serine threonine protein kinase
FGW37_RS00970	COG2072	flavoprotein involved in K transport
FGW37_RS00975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGW37_RS00995	COG0596	Alpha beta hydrolase
FGW37_RS01015	COG2226	methyltransferase
FGW37_RS01025	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FGW37_RS01030	COG1120	ATPase activity
FGW37_RS01045	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FGW37_RS01060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGW37_RS01065	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGW37_RS01070	COG1618	nucleotide phosphatase activity, acting on free nucleotides
FGW37_RS01085	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FGW37_RS01090	COG1595	DNA-templated transcription, initiation
FGW37_RS01095	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGW37_RS01100	COG0659	secondary active sulfate transmembrane transporter activity
FGW37_RS01105	COG3973	AAA domain
FGW37_RS01120	COG1794	racemase activity, acting on amino acids and derivatives
FGW37_RS01135	COG0277	FAD linked oxidase domain protein
FGW37_RS01140	COG0590	tRNA wobble adenosine to inosine editing
FGW37_RS01220	COG0477	Major facilitator Superfamily
FGW37_RS01225	COG0681	Belongs to the peptidase S26 family
FGW37_RS01305	COG3251	PFAM MbtH domain protein
FGW37_RS01315	COG5285	phytanoyl-CoA dioxygenase
FGW37_RS01340	COG2124	cytochrome p450
FGW37_RS01350	COG1070	Carbohydrate kinase
FGW37_RS01355	COG1070	Carbohydrate kinase
FGW37_RS01385	COG0702	epimerase
FGW37_RS01400	COG1215	transferase activity, transferring glycosyl groups
FGW37_RS01410	COG1122	ATPase activity
FGW37_RS01455	COG2197	response regulator
FGW37_RS01460	COG4585	Histidine kinase
FGW37_RS01470	COG4585	Histidine kinase
FGW37_RS01475	COG2197	response regulator
FGW37_RS01510	COG0142	geranyltranstransferase activity
FGW37_RS01535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGW37_RS01540	COG3842	ATPase activity
FGW37_RS01545	COG0803	Belongs to the bacterial solute-binding protein 9 family
FGW37_RS01565	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS01580	COG1476	TRANSCRIPTIONal
FGW37_RS01605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGW37_RS01630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGW37_RS01635	COG0583	DNA-binding transcription factor activity
FGW37_RS01690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FGW37_RS01695	COG2205	protein histidine kinase activity
FGW37_RS01700	COG0745	RESPONSE REGULATOR receiver
FGW37_RS01720	COG0598	Magnesium transport protein CorA
FGW37_RS01740	COG0596	Alpha beta hydrolase
FGW37_RS01745	COG1309	transcriptional regulator
FGW37_RS01750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGW37_RS01795	COG1222	aaa ATPase
FGW37_RS01875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGW37_RS01885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGW37_RS01895	COG3629	intracellular signal transduction
FGW37_RS01955	COG1802	Transcriptional regulator
FGW37_RS01965	COG3938	Belongs to the proline racemase family
FGW37_RS01970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGW37_RS01985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGW37_RS01990	COG0006	proline dipeptidase activity
FGW37_RS02000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGW37_RS02015	COG4608	Belongs to the ABC transporter superfamily
FGW37_RS02030	COG2824	Alkylphosphonate utilization operon protein PhnA
FGW37_RS02035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGW37_RS02045	COG0589	response to stress
FGW37_RS02055	COG3979	chitinase
FGW37_RS02065	COG0745	RESPONSE REGULATOR receiver
FGW37_RS02080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGW37_RS02115	COG0702	epimerase
FGW37_RS02125	COG0688	phosphatidylethanolamine metabolic process
FGW37_RS02140	COG0789	Transcriptional regulator
FGW37_RS02145	COG2814	Major facilitator Superfamily
FGW37_RS02160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FGW37_RS02165	COG1764	response to oxidative stress
FGW37_RS02170	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FGW37_RS02180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FGW37_RS02185	COG0113	porphobilinogen synthase activity
FGW37_RS02225	COG2814	Major facilitator Superfamily
FGW37_RS02230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGW37_RS02245	COG1309	transcriptional regulator
FGW37_RS02280	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGW37_RS02285	COG3226	Transcriptional regulator
FGW37_RS02295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FGW37_RS02315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FGW37_RS02390	COG0431	NADPH-dependent FMN reductase
FGW37_RS02440	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS02485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGW37_RS02490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGW37_RS02495	COG0463	Glycosyl transferase, family 2
FGW37_RS02510	COG1316	TRANSCRIPTIONal
FGW37_RS02525	COG2197	response regulator
FGW37_RS02540	COG1136	(ABC) transporter
FGW37_RS02550	COG3321	synthase
FGW37_RS02550	COG0604	alcohol dehydrogenase
FGW37_RS02590	COG0019	diaminopimelate decarboxylase activity
FGW37_RS02595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS02600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS02615	COG2267	carboxylic ester hydrolase activity
FGW37_RS02620	COG2124	cytochrome p450
FGW37_RS02625	COG2124	cytochrome p450
FGW37_RS02635	COG3118	belongs to the thioredoxin family
FGW37_RS02665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FGW37_RS02670	COG1959	2 iron, 2 sulfur cluster binding
FGW37_RS02675	COG3321	synthase
FGW37_RS02675	COG0604	alcohol dehydrogenase
FGW37_RS02680	COG1278	Cold shock
FGW37_RS02700	COG0583	DNA-binding transcription factor activity
FGW37_RS02725	COG2080	2 iron, 2 sulfur cluster binding
FGW37_RS02730	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FGW37_RS02735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGW37_RS02765	COG4249	Peptidase C14 caspase catalytic subunit p20
FGW37_RS02765	COG2319	Wd-40 repeat
FGW37_RS02785	COG0745	RESPONSE REGULATOR receiver
FGW37_RS02790	COG5002	protein histidine kinase activity
FGW37_RS02795	COG3135	benzoate transporter
FGW37_RS02800	COG0590	tRNA wobble adenosine to inosine editing
FGW37_RS02830	COG2267	carboxylic ester hydrolase activity
FGW37_RS02835	COG0561	phosphatase activity
FGW37_RS02865	COG4585	Histidine kinase
FGW37_RS02870	COG2197	response regulator
FGW37_RS02890	COG0328	RNA-DNA hybrid ribonuclease activity
FGW37_RS02910	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS02925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS02970	COG0477	Major facilitator Superfamily
FGW37_RS02975	COG0688	phosphatidylethanolamine metabolic process
FGW37_RS02990	COG4566	intracellular signal transduction
FGW37_RS03005	COG0477	Major facilitator Superfamily
FGW37_RS03015	COG4106	trans-aconitate 2-methyltransferase activity
FGW37_RS03105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGW37_RS03110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGW37_RS03115	COG4948	Mandelate Racemase Muconate Lactonizing
FGW37_RS03160	COG1686	Belongs to the peptidase S11 family
FGW37_RS03165	COG1063	alcohol dehydrogenase
FGW37_RS03170	COG0156	8-amino-7-oxononanoate synthase activity
FGW37_RS03185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGW37_RS03205	COG0367	asparagine synthase
FGW37_RS03210	COG0477	Major facilitator Superfamily
FGW37_RS03220	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS03225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGW37_RS03230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGW37_RS03240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGW37_RS03250	COG0443	Heat shock 70 kDa protein
FGW37_RS03270	COG0584	glycerophosphoryl diester phosphodiesterase
FGW37_RS03300	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FGW37_RS03320	COG0726	polysaccharide deacetylase
FGW37_RS03330	COG3012	SEC-C Motif Domain Protein
FGW37_RS03350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FGW37_RS03355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGW37_RS03365	COG0438	transferase activity, transferring glycosyl groups
FGW37_RS03435	COG3226	Transcriptional regulator
FGW37_RS03475	COG1024	Enoyl-CoA hydratase
FGW37_RS03490	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS03520	COG0789	Transcriptional regulator
FGW37_RS03675	COG0515	serine threonine protein kinase
FGW37_RS03685	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS03750	COG4585	Histidine kinase
FGW37_RS03755	COG2197	response regulator
FGW37_RS03790	COG2124	cytochrome p450
FGW37_RS03805	COG0204	Acyl-transferase
FGW37_RS03830	COG2267	carboxylic ester hydrolase activity
FGW37_RS03860	COG0346	lactoylglutathione lyase activity
FGW37_RS03865	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS03875	COG0242	peptide deformylase activity
FGW37_RS03885	COG3442	glutamine amidotransferase
FGW37_RS03890	COG0205	6-phosphofructokinase activity
FGW37_RS03925	COG0829	nickel cation binding
FGW37_RS03930	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FGW37_RS03940	COG0804	urea catabolic process
FGW37_RS03945	COG0832	Belongs to the urease beta subunit family
FGW37_RS03950	COG0831	urea catabolic process
FGW37_RS03975	COG0156	8-amino-7-oxononanoate synthase activity
FGW37_RS03980	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FGW37_RS03985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FGW37_RS03990	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FGW37_RS04025	COG1595	DNA-templated transcription, initiation
FGW37_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS04035	COG2188	Transcriptional regulator
FGW37_RS04040	COG1940	carbohydrate kinase activity
FGW37_RS04045	COG2197	response regulator
FGW37_RS04050	COG4585	Histidine kinase
FGW37_RS04070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGW37_RS04090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGW37_RS04120	COG1522	sequence-specific DNA binding
FGW37_RS04125	COG0419	ATPase involved in DNA repair
FGW37_RS04130	COG0420	3'-5' exonuclease activity
FGW37_RS04140	COG1739	Uncharacterized protein family UPF0029
FGW37_RS04145	COG1832	CoA-binding protein
FGW37_RS04180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGW37_RS04195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGW37_RS04215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGW37_RS04220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGW37_RS04230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGW37_RS04235	COG0477	Major facilitator Superfamily
FGW37_RS04260	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS04275	COG3903	Transcriptional regulator
FGW37_RS04275	COG3629	intracellular signal transduction
FGW37_RS04305	COG0659	secondary active sulfate transmembrane transporter activity
FGW37_RS04315	COG0604	alcohol dehydrogenase
FGW37_RS04315	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS04315	COG3321	synthase
FGW37_RS04330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGW37_RS04350	COG0110	maltose O-acetyltransferase activity
FGW37_RS04370	COG4566	intracellular signal transduction
FGW37_RS04395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGW37_RS04410	COG1968	undecaprenyl-diphosphatase activity
FGW37_RS04435	COG2340	Cysteine-rich secretory protein family
FGW37_RS04475	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FGW37_RS04475	COG1796	DNA polymerase
FGW37_RS04480	COG1793	dna ligase
FGW37_RS04480	COG3285	dna ligase
FGW37_RS04485	COG1793	dna ligase
FGW37_RS04485	COG3285	dna ligase
FGW37_RS04490	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FGW37_RS04535	COG2318	DinB family
FGW37_RS04545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGW37_RS04585	COG0583	DNA-binding transcription factor activity
FGW37_RS04590	COG0697	spore germination
FGW37_RS04650	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGW37_RS04650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGW37_RS04660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGW37_RS04680	COG1716	ATPase activity
FGW37_RS04700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FGW37_RS04730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGW37_RS04750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGW37_RS04760	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FGW37_RS04765	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGW37_RS04780	COG2018	Roadblock/LC7 domain
FGW37_RS04820	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FGW37_RS04835	COG2186	Transcriptional regulator
FGW37_RS04840	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FGW37_RS04845	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FGW37_RS04850	COG1984	allophanate hydrolase subunit 2
FGW37_RS04890	COG0745	RESPONSE REGULATOR receiver
FGW37_RS04900	COG0772	Belongs to the SEDS family
FGW37_RS04910	COG2272	Belongs to the type-B carboxylesterase lipase family
FGW37_RS04915	COG1793	dna ligase
FGW37_RS04985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGW37_RS05010	COG2186	Transcriptional regulator
FGW37_RS05030	COG0463	Glycosyl transferase, family 2
FGW37_RS05055	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS05070	COG1461	Dihydroxyacetone kinase
FGW37_RS05090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS05095	COG1120	ATPase activity
FGW37_RS05155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FGW37_RS05320	COG5280	Phage tail tape measure protein TP901
FGW37_RS05320	COG3953	SLT domain
FGW37_RS05440	COG0181	hydroxymethylbilane synthase activity
FGW37_RS05450	COG0181	hydroxymethylbilane synthase activity
FGW37_RS05455	COG0113	porphobilinogen synthase activity
FGW37_RS05495	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS05520	COG0477	Major facilitator Superfamily
FGW37_RS05550	COG5001	Diguanylate cyclase
FGW37_RS05580	COG2233	PERMEase
FGW37_RS05590	COG0738	Major facilitator superfamily
FGW37_RS05610	COG3201	nicotinamide mononucleotide transporter
FGW37_RS05615	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGW37_RS05615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGW37_RS05620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FGW37_RS05625	COG0140	phosphoribosyl-ATP diphosphatase activity
FGW37_RS05630	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FGW37_RS05705	COG0583	DNA-binding transcription factor activity
FGW37_RS05710	COG2814	Major facilitator Superfamily
FGW37_RS05735	COG0300	oxidoreductase activity
FGW37_RS05740	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FGW37_RS05750	COG2390	Transcriptional regulator
FGW37_RS05755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FGW37_RS05765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGW37_RS05780	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGW37_RS05805	COG0284	orotidine-5'-phosphate decarboxylase activity
FGW37_RS05810	COG0167	dihydroorotate dehydrogenase activity
FGW37_RS05815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGW37_RS05820	COG0505	Belongs to the CarA family
FGW37_RS05830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FGW37_RS05835	COG0540	Belongs to the ATCase OTCase family
FGW37_RS05840	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FGW37_RS05850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGW37_RS05855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGW37_RS05860	COG0006	proline dipeptidase activity
FGW37_RS05870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FGW37_RS05875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGW37_RS05880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGW37_RS05885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGW37_RS05890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGW37_RS05895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FGW37_RS05900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FGW37_RS05905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGW37_RS05925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGW37_RS05945	COG0124	histidyl-tRNA synthetase
FGW37_RS05955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGW37_RS05960	COG1196	nuclear chromosome segregation
FGW37_RS05965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGW37_RS05970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGW37_RS05975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGW37_RS05980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGW37_RS05990	COG2255	four-way junction helicase activity
FGW37_RS05995	COG0632	four-way junction helicase activity
FGW37_RS06000	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FGW37_RS06005	COG0217	transcriptional regulatory protein
FGW37_RS06010	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FGW37_RS06015	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FGW37_RS06025	COG0438	transferase activity, transferring glycosyl groups
FGW37_RS06030	COG1560	Kdo2-lipid A biosynthetic process
FGW37_RS06035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FGW37_RS06065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGW37_RS06080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGW37_RS06135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGW37_RS06185	COG1648	precorrin-2 dehydrogenase activity
FGW37_RS06185	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGW37_RS06190	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FGW37_RS06205	COG1464	Belongs to the NlpA lipoprotein family
FGW37_RS06210	COG2011	ABC-type metal ion transport system permease component
FGW37_RS06215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGW37_RS06250	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FGW37_RS06255	COG0477	Major facilitator Superfamily
FGW37_RS06265	COG0165	Argininosuccinate lyase
FGW37_RS06270	COG0137	argininosuccinate synthase activity
FGW37_RS06280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FGW37_RS06285	COG1438	arginine binding
FGW37_RS06290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGW37_RS06295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGW37_RS06300	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FGW37_RS06305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGW37_RS06330	COG0697	spore germination
FGW37_RS06345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGW37_RS06350	COG0697	spore germination
FGW37_RS06360	COG1649	PFAM Uncharacterised BCR, COG1649
FGW37_RS06390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGW37_RS06390	COG0072	phenylalanine-tRNA ligase activity
FGW37_RS06395	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGW37_RS06400	COG5002	protein histidine kinase activity
FGW37_RS06405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGW37_RS06410	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FGW37_RS06415	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FGW37_RS06420	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FGW37_RS06430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGW37_RS06475	COG2186	Transcriptional regulator
FGW37_RS06480	COG1113	amino acid transport
FGW37_RS06485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FGW37_RS06510	COG4175	Glycine betaine
FGW37_RS06510	COG0517	IMP dehydrogenase activity
FGW37_RS06515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGW37_RS06535	COG0805	protein transport
FGW37_RS06540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGW37_RS06560	COG2378	regulation of single-species biofilm formation
FGW37_RS06570	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGW37_RS06575	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FGW37_RS06585	COG1609	Transcriptional regulator
FGW37_RS06590	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FGW37_RS06595	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FGW37_RS06610	COG4122	O-methyltransferase activity
FGW37_RS06615	COG1222	aaa ATPase
FGW37_RS06635	COG0517	IMP dehydrogenase activity
FGW37_RS06635	COG1994	Peptidase M50
FGW37_RS06645	COG2197	response regulator
FGW37_RS06655	COG4166	transmembrane transport
FGW37_RS06660	COG0546	phosphoglycolate phosphatase activity
FGW37_RS06675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FGW37_RS06680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGW37_RS06685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGW37_RS06690	COG1414	Transcriptional regulator
FGW37_RS06695	COG1410	methionine synthase
FGW37_RS06695	COG0646	methionine synthase
FGW37_RS06710	COG0215	cysteine-tRNA ligase activity
FGW37_RS06730	COG0598	Magnesium transport protein CorA
FGW37_RS06740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGW37_RS06745	COG0667	Aldo Keto reductase
FGW37_RS06775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGW37_RS06805	COG1834	amidinotransferase
FGW37_RS06830	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FGW37_RS06840	COG0477	Major facilitator Superfamily
FGW37_RS06845	COG1846	Transcriptional regulator
FGW37_RS06900	COG3876	Protein conserved in bacteria
FGW37_RS06920	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FGW37_RS06925	COG2188	Transcriptional regulator
FGW37_RS06950	COG0515	serine threonine protein kinase
FGW37_RS06955	COG2755	lipolytic protein G-D-S-L family
FGW37_RS06975	COG1215	transferase activity, transferring glycosyl groups
FGW37_RS07000	COG1725	Transcriptional regulator
FGW37_RS07005	COG0367	asparagine synthase
FGW37_RS07015	COG4264	IucA IucC family
FGW37_RS07020	COG2814	Major facilitator Superfamily
FGW37_RS07035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGW37_RS07040	COG1120	ATPase activity
FGW37_RS07045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS07050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS07065	COG0531	amino acid
FGW37_RS07095	COG0587	DNA-directed DNA polymerase activity
FGW37_RS07100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGW37_RS07115	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FGW37_RS07130	COG0601	transmembrane transport
FGW37_RS07135	COG4166	transmembrane transport
FGW37_RS07155	COG0330	HflC and HflK could
FGW37_RS07170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGW37_RS07185	COG1799	cell septum assembly
FGW37_RS07190	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS07195	COG0477	Major facilitator Superfamily
FGW37_RS07205	COG0671	phosphoesterase, PA-phosphatase related
FGW37_RS07215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FGW37_RS07225	COG0438	transferase activity, transferring glycosyl groups
FGW37_RS07240	COG1160	GTP binding
FGW37_RS07250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FGW37_RS07270	COG1187	pseudouridine synthase activity
FGW37_RS07275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FGW37_RS07280	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FGW37_RS07295	COG0686	Belongs to the AlaDH PNT family
FGW37_RS07305	COG0494	nUDIX hydrolase
FGW37_RS07310	COG0504	CTP synthase activity
FGW37_RS07315	COG3387	PFAM Glycoside hydrolase 15-related
FGW37_RS07320	COG0477	Major facilitator Superfamily
FGW37_RS07330	COG1357	PFAM Pentapeptide repeats (8 copies)
FGW37_RS07335	COG0297	glycogen (starch) synthase activity
FGW37_RS07345	COG0497	DNA recombination
FGW37_RS07355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGW37_RS07375	COG1120	ATPase activity
FGW37_RS07380	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS07385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS07400	COG0647	UMP catabolic process
FGW37_RS07430	COG2094	Belongs to the DNA glycosylase MPG family
FGW37_RS07445	COG4290	ribonuclease
FGW37_RS07450	COG1881	PFAM PEBP family protein
FGW37_RS07475	COG1119	ATPase activity
FGW37_RS07495	COG2197	response regulator
FGW37_RS07500	COG3850	Histidine kinase
FGW37_RS07510	COG5280	Phage tail tape measure protein TP901
FGW37_RS07510	COG3953	SLT domain
FGW37_RS07515	COG1131	(ABC) transporter
FGW37_RS07515	COG0842	Transport permease protein
FGW37_RS07515	COG1716	ATPase activity
FGW37_RS07525	COG3830	Belongs to the UPF0237 family
FGW37_RS07525	COG0560	Phosphoserine phosphatase
FGW37_RS07540	COG2807	transmembrane transport
FGW37_RS07545	COG2186	Transcriptional regulator
FGW37_RS07555	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGW37_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS07575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGW37_RS07580	COG2261	transglycosylase associated protein
FGW37_RS07595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FGW37_RS07600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGW37_RS07625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGW37_RS07635	COG3387	PFAM Glycoside hydrolase 15-related
FGW37_RS07685	COG1024	Enoyl-CoA hydratase
FGW37_RS07695	COG0488	(ABC) transporter
FGW37_RS07725	COG0235	Class ii aldolase
FGW37_RS07740	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FGW37_RS07745	COG1492	cobalamin metabolic process
FGW37_RS07760	COG1797	cobyrinic acid a,c-diamide synthase activity
FGW37_RS07780	COG0385	Bile acid
FGW37_RS07790	COG0456	acetyltransferase
FGW37_RS07800	COG1917	Cupin 2, conserved barrel domain protein
FGW37_RS07805	COG5285	phytanoyl-CoA dioxygenase
FGW37_RS07810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGW37_RS07820	COG4585	Histidine kinase
FGW37_RS07835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGW37_RS07845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGW37_RS07865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGW37_RS07870	COG2171	N-acyltransferase activity
FGW37_RS07880	COG2957	Belongs to the agmatine deiminase family
FGW37_RS07890	COG0822	iron-sulfur transferase activity
FGW37_RS07895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGW37_RS07900	COG0396	ATPase activity
FGW37_RS07910	COG0719	Fe-S assembly protein
FGW37_RS07925	COG1131	(ABC) transporter
FGW37_RS07935	COG1612	heme a metabolic process
FGW37_RS07950	COG0109	protoheme IX farnesyltransferase activity
FGW37_RS07955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FGW37_RS07960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGW37_RS07975	COG0363	glucosamine-6-phosphate deaminase activity
FGW37_RS07980	COG0166	Belongs to the GPI family
FGW37_RS07990	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FGW37_RS07995	COG0149	triose-phosphate isomerase activity
FGW37_RS08000	COG0126	phosphoglycerate kinase activity
FGW37_RS08005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FGW37_RS08015	COG1481	regulation of sporulation
FGW37_RS08020	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FGW37_RS08025	COG1660	Displays ATPase and GTPase activities
FGW37_RS08030	COG0322	excinuclease ABC activity
FGW37_RS08060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGW37_RS08075	COG0477	Major facilitator Superfamily
FGW37_RS08095	COG0556	nucleotide-excision repair
FGW37_RS08100	COG0584	glycerophosphoryl diester phosphodiesterase
FGW37_RS08105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGW37_RS08140	COG0237	dephospho-CoA kinase activity
FGW37_RS08150	COG0539	negative regulation of cytoplasmic translation
FGW37_RS08155	COG2226	methyltransferase
FGW37_RS08160	COG1643	Atp-dependent helicase
FGW37_RS08170	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FGW37_RS08190	COG2050	protein possibly involved in aromatic compounds catabolism
FGW37_RS08205	COG0559	Belongs to the binding-protein-dependent transport system permease family
FGW37_RS08250	COG0737	Belongs to the 5'-nucleotidase family
FGW37_RS08265	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGW37_RS08275	COG0287	Prephenate dehydrogenase
FGW37_RS08275	COG1605	Chorismate mutase
FGW37_RS08280	COG2207	Transcriptional regulator
FGW37_RS08285	COG1470	cell adhesion involved in biofilm formation
FGW37_RS08285	COG0366	Alpha amylase catalytic
FGW37_RS08295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGW37_RS08305	COG2197	response regulator
FGW37_RS08340	COG1215	transferase activity, transferring glycosyl groups
FGW37_RS08345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FGW37_RS08360	COG0070	glutamate synthase
FGW37_RS08360	COG0067	glutamate synthase
FGW37_RS08360	COG0069	glutamate synthase activity
FGW37_RS08370	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FGW37_RS08380	COG0159	tryptophan synthase activity
FGW37_RS08385	COG0133	tryptophan synthase activity
FGW37_RS08390	COG0134	indole-3-glycerol-phosphate synthase activity
FGW37_RS08410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGW37_RS08415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FGW37_RS08430	COG2259	Doxx family
FGW37_RS08435	COG0107	imidazoleglycerol-phosphate synthase activity
FGW37_RS08440	COG0251	oxidation-reduction process
FGW37_RS08445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FGW37_RS08450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FGW37_RS08460	COG0131	Imidazoleglycerol-phosphate dehydratase
FGW37_RS08465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGW37_RS08470	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FGW37_RS08480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FGW37_RS08505	COG1432	Conserved Protein
FGW37_RS08515	COG0587	DNA-directed DNA polymerase activity
FGW37_RS08575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FGW37_RS08585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FGW37_RS08590	COG3599	regulation of cell shape
FGW37_RS08600	COG1799	cell septum assembly
FGW37_RS08620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FGW37_RS08625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGW37_RS08635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGW37_RS08640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGW37_RS08650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGW37_RS08655	COG0768	penicillin binding
FGW37_RS08665	COG0275	rRNA processing
FGW37_RS08675	COG0714	Associated with various cellular activities
FGW37_RS08700	COG1309	transcriptional regulator
FGW37_RS08705	COG1233	COG1233 Phytoene dehydrogenase and related
FGW37_RS08720	COG0352	thiamine-phosphate diphosphorylase activity
FGW37_RS08735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGW37_RS08735	COG2022	thiamine diphosphate biosynthetic process
FGW37_RS08745	COG2022	thiamine diphosphate biosynthetic process
FGW37_RS08750	COG2815	serine threonine protein kinase
FGW37_RS08750	COG0515	serine threonine protein kinase
FGW37_RS08755	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FGW37_RS08760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FGW37_RS08765	COG2193	ferroxidase activity
FGW37_RS08770	COG0243	molybdopterin cofactor binding
FGW37_RS08775	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FGW37_RS08790	COG0205	6-phosphofructokinase activity
FGW37_RS08795	COG2197	response regulator
FGW37_RS08825	COG1940	carbohydrate kinase activity
FGW37_RS08835	COG0003	Pfam Anion-transporting ATPase
FGW37_RS08870	COG0791	NLP P60 protein
FGW37_RS08890	COG0705	Rhomboid family
FGW37_RS08900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGW37_RS08905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGW37_RS08910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FGW37_RS08915	COG0723	plastoquinol--plastocyanin reductase activity
FGW37_RS08920	COG2010	Cytochrome c
FGW37_RS08925	COG1845	cytochrome c oxidase, subunit III
FGW37_RS08935	COG1376	ErfK ybiS ycfS ynhG family protein
FGW37_RS08945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FGW37_RS08950	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FGW37_RS08960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGW37_RS08980	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FGW37_RS08985	COG2197	response regulator
FGW37_RS09000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGW37_RS09025	COG4585	Histidine kinase
FGW37_RS09030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FGW37_RS09035	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGW37_RS09035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGW37_RS09050	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FGW37_RS09055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGW37_RS09060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGW37_RS09065	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGW37_RS09080	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS09095	COG1090	epimerase
FGW37_RS09110	COG0321	lipoyl(octanoyl) transferase activity
FGW37_RS09115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FGW37_RS09145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGW37_RS09195	COG4974	Belongs to the 'phage' integrase family
FGW37_RS09225	COG3387	PFAM Glycoside hydrolase 15-related
FGW37_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS09250	COG0745	RESPONSE REGULATOR receiver
FGW37_RS09260	COG2197	response regulator
FGW37_RS09270	COG2365	Tyrosine phosphatase family
FGW37_RS09295	COG1653	transport
FGW37_RS09305	COG3833	ABC-type maltose transport systems, permease component
FGW37_RS09310	COG0366	Alpha amylase catalytic
FGW37_RS09315	COG1609	Transcriptional regulator
FGW37_RS09325	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FGW37_RS09330	COG0174	glutamine synthetase
FGW37_RS09335	COG2267	carboxylic ester hydrolase activity
FGW37_RS09340	COG0531	amino acid
FGW37_RS09350	COG2132	Multicopper oxidase
FGW37_RS09355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGW37_RS09355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FGW37_RS09400	COG1994	Peptidase M50
FGW37_RS09420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FGW37_RS09425	COG0477	Major facilitator Superfamily
FGW37_RS09430	COG1309	transcriptional regulator
FGW37_RS09440	COG2814	Major facilitator Superfamily
FGW37_RS09445	COG0740	serine-type endopeptidase activity
FGW37_RS09450	COG0740	serine-type endopeptidase activity
FGW37_RS09455	COG1396	sequence-specific DNA binding
FGW37_RS09520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS09525	COG1120	ATPase activity
FGW37_RS09535	COG2837	iron assimilation
FGW37_RS09540	COG0672	)-iron permease
FGW37_RS09565	COG1834	amidinotransferase
FGW37_RS09575	COG2814	Major facilitator Superfamily
FGW37_RS09580	COG3540	Alkaline phosphatase
FGW37_RS09595	COG0800	Aldolase
FGW37_RS09600	COG3022	response to hydroperoxide
FGW37_RS09605	COG0557	exoribonuclease II activity
FGW37_RS09615	COG2197	response regulator
FGW37_RS09620	COG4585	Histidine kinase
FGW37_RS09625	COG2030	dehydratase
FGW37_RS09650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGW37_RS09655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FGW37_RS09680	COG3510	cephalosporin hydroxylase
FGW37_RS09685	COG0860	N-Acetylmuramoyl-L-alanine amidase
FGW37_RS09695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGW37_RS09735	COG1309	transcriptional regulator
FGW37_RS09740	COG2197	response regulator
FGW37_RS09750	COG1132	(ABC) transporter
FGW37_RS09760	COG0515	serine threonine protein kinase
FGW37_RS09790	COG3845	ABC transporter
FGW37_RS09800	COG1834	amidinotransferase
FGW37_RS09840	COG0688	phosphatidylethanolamine metabolic process
FGW37_RS09845	COG0183	Belongs to the thiolase family
FGW37_RS09850	COG2124	cytochrome p450
FGW37_RS09890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGW37_RS09930	COG5640	endopeptidase activity
FGW37_RS09935	COG0583	DNA-binding transcription factor activity
FGW37_RS09980	COG1358	cellular component organization or biogenesis
FGW37_RS10025	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FGW37_RS10035	COG0477	Major facilitator Superfamily
FGW37_RS10040	COG1309	transcriptional regulator
FGW37_RS10055	COG4585	Histidine kinase
FGW37_RS10060	COG2197	response regulator
FGW37_RS10065	COG0667	Aldo Keto reductase
FGW37_RS10070	COG0789	Transcriptional regulator
FGW37_RS10095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGW37_RS10100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGW37_RS10105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGW37_RS10135	COG2130	NADP-dependent
FGW37_RS10155	COG1285	pathogenesis
FGW37_RS10165	COG2318	DinB family
FGW37_RS10175	COG1116	anion transmembrane transporter activity
FGW37_RS10200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGW37_RS10225	COG1070	Carbohydrate kinase
FGW37_RS10235	COG0358	DNA primase activity
FGW37_RS10245	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FGW37_RS10250	COG2949	membrane
FGW37_RS10255	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FGW37_RS10280	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS10290	COG0531	amino acid
FGW37_RS10300	COG1175	transmembrane transport
FGW37_RS10305	COG0395	ABC-type sugar transport system, permease component
FGW37_RS10315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGW37_RS10315	COG0574	Belongs to the PEP-utilizing enzyme family
FGW37_RS10340	COG0477	Major facilitator Superfamily
FGW37_RS10345	COG0667	Aldo Keto reductase
FGW37_RS10355	COG2197	response regulator
FGW37_RS10370	COG0423	glycine-tRNA ligase activity
FGW37_RS10375	COG3443	Belongs to the bacterial solute-binding protein 9 family
FGW37_RS10375	COG0803	Belongs to the bacterial solute-binding protein 9 family
FGW37_RS10380	COG1121	(ABC) transporter
FGW37_RS10385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGW37_RS10395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGW37_RS10400	COG1381	Involved in DNA repair and RecF pathway recombination
FGW37_RS10420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGW37_RS10435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FGW37_RS10470	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGW37_RS10485	COG1486	melibiose metabolic process
FGW37_RS10490	COG1234	tRNA 3'-trailer cleavage
FGW37_RS10495	COG0537	adenosine 5'-monophosphoramidase activity
FGW37_RS10505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGW37_RS10525	COG0463	Glycosyl transferase, family 2
FGW37_RS10545	COG0456	acetyltransferase
FGW37_RS10585	COG0484	heat shock protein binding
FGW37_RS10590	COG1420	regulation of RNA biosynthetic process
FGW37_RS10615	COG0481	GTPase activity
FGW37_RS10620	COG0268	Binds directly to 16S ribosomal RNA
FGW37_RS10640	COG1234	tRNA 3'-trailer cleavage
FGW37_RS10650	COG1307	EDD domain protein, DegV family
FGW37_RS10660	COG0495	leucyl-tRNA aminoacylation
FGW37_RS10695	COG0588	phosphoglycerate mutase activity
FGW37_RS10700	COG0799	negative regulation of ribosome biogenesis
FGW37_RS10710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGW37_RS10725	COG0501	Belongs to the peptidase M48B family
FGW37_RS10740	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FGW37_RS10750	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FGW37_RS10760	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGW37_RS10765	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FGW37_RS10770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FGW37_RS10775	COG1530	ribonuclease E activity
FGW37_RS10790	COG3025	triphosphatase activity
FGW37_RS10790	COG5607	PFAM CHAD domain containing protein
FGW37_RS10795	COG0772	Belongs to the SEDS family
FGW37_RS10800	COG0768	penicillin binding
FGW37_RS10815	COG1077	Cell shape determining protein MreB Mrl
FGW37_RS10820	COG0105	UTP biosynthetic process
FGW37_RS10830	COG0285	dihydrofolate synthase activity
FGW37_RS10850	COG1215	transferase activity, transferring glycosyl groups
FGW37_RS10860	COG0525	valine-tRNA ligase activity
FGW37_RS10910	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FGW37_RS10915	COG0740	serine-type endopeptidase activity
FGW37_RS10920	COG0740	serine-type endopeptidase activity
FGW37_RS10925	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGW37_RS10945	COG3594	Acyltransferase
FGW37_RS10960	COG4552	Acetyltransferase involved in intracellular survival and related
FGW37_RS10975	COG1113	amino acid transport
FGW37_RS10985	COG1113	amino acid transport
FGW37_RS10990	COG1113	amino acid transport
FGW37_RS10995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FGW37_RS11005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FGW37_RS11075	COG3291	Pkd domain containing protein
FGW37_RS11075	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FGW37_RS11085	COG0668	transmembrane transport
FGW37_RS11095	COG1940	carbohydrate kinase activity
FGW37_RS11095	COG1846	Transcriptional regulator
FGW37_RS11100	COG1486	melibiose metabolic process
FGW37_RS11125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGW37_RS11155	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGW37_RS11185	COG0629	single-stranded DNA binding
FGW37_RS11235	COG1192	Involved in chromosome partitioning
FGW37_RS11245	COG0640	Transcriptional regulator
FGW37_RS11270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGW37_RS11275	COG1993	acr, cog1993
FGW37_RS11280	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGW37_RS11285	COG0583	DNA-binding transcription factor activity
FGW37_RS11295	COG1053	succinate dehydrogenase
FGW37_RS11300	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FGW37_RS11320	COG3226	Transcriptional regulator
FGW37_RS11335	COG3962	Belongs to the TPP enzyme family
FGW37_RS11340	COG3718	enzyme involved in inositol metabolism
FGW37_RS11350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGW37_RS11360	COG0673	inositol 2-dehydrogenase activity
FGW37_RS11385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGW37_RS11430	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FGW37_RS11450	COG1946	Acyl-CoA thioesterase
FGW37_RS11460	COG1309	transcriptional regulator
FGW37_RS11465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGW37_RS11480	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS11500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGW37_RS11505	COG0589	response to stress
FGW37_RS11515	COG4977	sequence-specific DNA binding
FGW37_RS11520	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FGW37_RS11565	COG0406	alpha-ribazole phosphatase activity
FGW37_RS11615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGW37_RS11635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGW37_RS11635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGW37_RS11640	COG4232	protein-disulfide reductase activity
FGW37_RS11645	COG3397	chitin binding
FGW37_RS11655	COG0741	lytic transglycosylase activity
FGW37_RS11655	COG0791	NLP P60 protein
FGW37_RS11715	COG0673	inositol 2-dehydrogenase activity
FGW37_RS11760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGW37_RS11770	COG2733	membrane
FGW37_RS11785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGW37_RS11795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGW37_RS11810	COG2205	protein histidine kinase activity
FGW37_RS11830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGW37_RS11840	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FGW37_RS11845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGW37_RS11850	COG1263	PTS System
FGW37_RS11855	COG1263	PTS System
FGW37_RS11860	COG1234	tRNA 3'-trailer cleavage
FGW37_RS11880	COG1113	amino acid transport
FGW37_RS11890	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FGW37_RS11900	COG1335	isochorismatase
FGW37_RS11935	COG0277	FAD linked oxidase domain protein
FGW37_RS11940	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FGW37_RS11950	COG1174	glycine betaine transport
FGW37_RS11955	COG0517	IMP dehydrogenase activity
FGW37_RS11955	COG1125	glycine betaine transport
FGW37_RS11960	COG1174	glycine betaine transport
FGW37_RS11985	COG0477	Major facilitator Superfamily
FGW37_RS11990	COG2855	membrane
FGW37_RS12000	COG0583	DNA-binding transcription factor activity
FGW37_RS12020	COG4221	oxidoreductase activity
FGW37_RS12025	COG0583	DNA-binding transcription factor activity
FGW37_RS12035	COG2188	Transcriptional regulator
FGW37_RS12085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGW37_RS12100	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FGW37_RS12105	COG0395	ABC-type sugar transport system, permease component
FGW37_RS12125	COG2814	Major facilitator Superfamily
FGW37_RS12135	COG1678	Uncharacterized ACR, COG1678
FGW37_RS12140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGW37_RS12145	COG0776	regulation of translation
FGW37_RS12155	COG3973	AAA domain
FGW37_RS12180	COG0583	DNA-binding transcription factor activity
FGW37_RS12200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FGW37_RS12205	COG0793	Belongs to the peptidase S41A family
FGW37_RS12210	COG2177	Part of the ABC transporter FtsEX involved in
FGW37_RS12215	COG2884	Cell division ATP-binding protein ftsE
FGW37_RS12230	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FGW37_RS12235	COG0515	serine threonine protein kinase
FGW37_RS12240	COG0515	serine threonine protein kinase
FGW37_RS12265	COG0395	ABC-type sugar transport system, permease component
FGW37_RS12275	COG1215	transferase activity, transferring glycosyl groups
FGW37_RS12285	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FGW37_RS12320	COG2902	Dehydrogenase
FGW37_RS12340	COG0653	protein targeting
FGW37_RS12350	COG3214	Protein conserved in bacteria
FGW37_RS12355	COG2197	response regulator
FGW37_RS12360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FGW37_RS12365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGW37_RS12370	COG0823	Involved in the tonB-independent uptake of proteins
FGW37_RS12375	COG5000	phosphorelay sensor kinase activity
FGW37_RS12375	COG5002	protein histidine kinase activity
FGW37_RS12380	COG0745	RESPONSE REGULATOR receiver
FGW37_RS12385	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FGW37_RS12415	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FGW37_RS12420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGW37_RS12420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGW37_RS12420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGW37_RS12430	COG1482	cell wall glycoprotein biosynthetic process
FGW37_RS12440	COG2835	tetraacyldisaccharide 4'-kinase activity
FGW37_RS12445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGW37_RS12480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FGW37_RS12485	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FGW37_RS12485	COG0778	Nitroreductase
FGW37_RS12510	COG1316	TRANSCRIPTIONal
FGW37_RS12515	COG1316	TRANSCRIPTIONal
FGW37_RS12520	COG1316	TRANSCRIPTIONal
FGW37_RS12530	COG1316	TRANSCRIPTIONal
FGW37_RS12535	COG1607	acyl-coa hydrolase
FGW37_RS12540	COG1316	TRANSCRIPTIONal
FGW37_RS12580	COG2205	protein histidine kinase activity
FGW37_RS12585	COG0745	RESPONSE REGULATOR receiver
FGW37_RS12590	COG3104	oligopeptide transport
FGW37_RS12620	COG1191	sigma factor activity
FGW37_RS12625	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FGW37_RS12640	COG1228	amidohydrolase
FGW37_RS12645	COG0667	Aldo Keto reductase
FGW37_RS12650	COG0789	Transcriptional regulator
FGW37_RS12675	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS12690	COG2755	lipolytic protein G-D-S-L family
FGW37_RS12695	COG0183	Belongs to the thiolase family
FGW37_RS12725	COG1136	(ABC) transporter
FGW37_RS12730	COG0577	efflux transmembrane transporter activity
FGW37_RS12735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGW37_RS12740	COG1252	NADH dehydrogenase
FGW37_RS12760	COG0148	phosphopyruvate hydratase activity
FGW37_RS12775	COG2124	cytochrome p450
FGW37_RS12795	COG0515	serine threonine protein kinase
FGW37_RS12795	COG2815	serine threonine protein kinase
FGW37_RS12840	COG0577	efflux transmembrane transporter activity
FGW37_RS12840	COG1136	(ABC) transporter
FGW37_RS12845	COG1136	(ABC) transporter
FGW37_RS12850	COG2814	Major facilitator Superfamily
FGW37_RS12885	COG4585	Histidine kinase
FGW37_RS12895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGW37_RS12900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGW37_RS12905	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FGW37_RS12910	COG0193	aminoacyl-tRNA hydrolase activity
FGW37_RS12925	COG0477	Major facilitator Superfamily
FGW37_RS12935	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FGW37_RS12945	COG1309	transcriptional regulator
FGW37_RS12950	COG4106	trans-aconitate 2-methyltransferase activity
FGW37_RS12955	COG1846	Transcriptional regulator
FGW37_RS12960	COG2197	response regulator
FGW37_RS12965	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FGW37_RS12990	COG0488	(ABC) transporter
FGW37_RS13020	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FGW37_RS13025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGW37_RS13035	COG0084	hydrolase, TatD family'
FGW37_RS13085	COG1122	ATPase activity
FGW37_RS13095	COG0310	cobalt ion transport
FGW37_RS13120	COG2409	Drug exporters of the RND superfamily
FGW37_RS13130	COG4946	Tricorn protease homolog
FGW37_RS13130	COG0793	Belongs to the peptidase S41A family
FGW37_RS13145	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS13150	COG2072	flavoprotein involved in K transport
FGW37_RS13175	COG2205	protein histidine kinase activity
FGW37_RS13195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGW37_RS13200	COG0315	cyclic pyranopterin monophosphate synthase activity
FGW37_RS13200	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGW37_RS13205	COG0315	cyclic pyranopterin monophosphate synthase activity
FGW37_RS13215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGW37_RS13220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FGW37_RS13245	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FGW37_RS13250	COG1970	mechanosensitive ion channel activity
FGW37_RS13295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGW37_RS13300	COG0477	Major facilitator Superfamily
FGW37_RS13320	COG3384	dioxygenase
FGW37_RS13325	COG1846	Transcriptional regulator
FGW37_RS13365	COG2124	cytochrome p450
FGW37_RS13370	COG2124	cytochrome p450
FGW37_RS13380	COG0514	ATP-dependent DNA helicase (RecQ)
FGW37_RS13410	COG1653	transport
FGW37_RS13420	COG1686	Belongs to the peptidase S11 family
FGW37_RS13450	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FGW37_RS13485	COG0702	epimerase
FGW37_RS13495	COG2353	YceI-like domain
FGW37_RS13500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FGW37_RS13525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGW37_RS13570	COG1024	Enoyl-CoA hydratase
FGW37_RS13575	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGW37_RS13575	COG0515	serine threonine protein kinase
FGW37_RS13580	COG1309	transcriptional regulator
FGW37_RS13590	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS13600	COG0259	pyridoxamine-phosphate oxidase activity
FGW37_RS13615	COG1024	Enoyl-CoA hydratase
FGW37_RS13620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FGW37_RS13650	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS13655	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS13670	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS13675	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS13710	COG1077	Cell shape determining protein MreB Mrl
FGW37_RS13720	COG0516	GMP reductase activity
FGW37_RS13730	COG1595	DNA-templated transcription, initiation
FGW37_RS13735	COG2197	response regulator
FGW37_RS13745	COG0583	DNA-binding transcription factor activity
FGW37_RS13755	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS13770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGW37_RS13775	COG0726	polysaccharide deacetylase
FGW37_RS13805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGW37_RS13830	COG0802	atpase or kinase
FGW37_RS13840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGW37_RS13880	COG0736	holo-[acyl-carrier-protein] synthase activity
FGW37_RS13885	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGW37_RS13895	COG1072	(Pantothenic acid kinase))
FGW37_RS13905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGW37_RS13910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FGW37_RS13915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FGW37_RS13920	COG0488	(ABC) transporter
FGW37_RS13935	COG0438	transferase activity, transferring glycosyl groups
FGW37_RS13940	COG0101	tRNA pseudouridine synthase activity
FGW37_RS13945	COG0203	ribosomal protein L17
FGW37_RS13955	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FGW37_RS13960	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGW37_RS13965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGW37_RS13970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGW37_RS13980	COG0563	adenylate kinase activity
FGW37_RS13990	COG0200	Binds to the 23S rRNA
FGW37_RS14000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGW37_RS14005	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FGW37_RS14010	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGW37_RS14015	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGW37_RS14020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGW37_RS14025	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGW37_RS14030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FGW37_RS14035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGW37_RS14040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FGW37_RS14045	COG0255	Belongs to the universal ribosomal protein uL29 family
FGW37_RS14050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGW37_RS14055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGW37_RS14060	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGW37_RS14065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGW37_RS14070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGW37_RS14075	COG0089	rRNA binding
FGW37_RS14080	COG0088	Forms part of the polypeptide exit tunnel
FGW37_RS14085	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGW37_RS14090	COG0051	transcription antitermination factor activity, RNA binding
FGW37_RS14105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGW37_RS14110	COG0049	tRNA binding
FGW37_RS14115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FGW37_RS14120	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGW37_RS14125	COG0085	RNA polymerase activity
FGW37_RS14130	COG0222	ribosome binding
FGW37_RS14145	COG0081	regulation of translation
FGW37_RS14150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FGW37_RS14155	COG0250	Participates in transcription elongation, termination and antitermination
FGW37_RS14170	COG0436	Aminotransferase
FGW37_RS14175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FGW37_RS14180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGW37_RS14185	COG0477	Major facilitator Superfamily
FGW37_RS14200	COG2030	dehydratase
FGW37_RS14205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGW37_RS14225	COG0702	epimerase
FGW37_RS14235	COG1666	GTP binding
FGW37_RS14240	COG3304	Inner membrane component domain
FGW37_RS14250	COG0501	Belongs to the peptidase M48B family
FGW37_RS14255	COG1007	ATP synthesis coupled electron transport
FGW37_RS14265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FGW37_RS14270	COG0713	ATP synthesis coupled electron transport
FGW37_RS14280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGW37_RS14285	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FGW37_RS14290	COG0649	NAD binding
FGW37_RS14290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGW37_RS14295	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGW37_RS14300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGW37_RS14310	COG4585	Histidine kinase
FGW37_RS14320	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FGW37_RS14320	COG0674	pyruvate-flavodoxin oxidoreductase activity
FGW37_RS14325	COG1013	pyruvate-flavodoxin oxidoreductase activity
FGW37_RS14330	COG0531	amino acid
FGW37_RS14340	COG2234	aminopeptidase activity
FGW37_RS14340	COG4935	Belongs to the peptidase S8 family
FGW37_RS14365	COG0492	ferredoxin-NADP+ reductase activity
FGW37_RS14390	COG1007	ATP synthesis coupled electron transport
FGW37_RS14400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FGW37_RS14405	COG0713	ATP synthesis coupled electron transport
FGW37_RS14410	COG0839	Belongs to the complex I subunit 6 family
FGW37_RS14415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGW37_RS14420	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FGW37_RS14425	COG1034	ATP synthesis coupled electron transport
FGW37_RS14430	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FGW37_RS14440	COG0649	NAD binding
FGW37_RS14445	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGW37_RS14450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGW37_RS14485	COG2226	methyltransferase
FGW37_RS14495	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FGW37_RS14500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGW37_RS14500	COG0515	serine threonine protein kinase
FGW37_RS14505	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FGW37_RS14510	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FGW37_RS14535	COG1309	transcriptional regulator
FGW37_RS14540	COG1301	dicarboxylic acid transport
FGW37_RS14550	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FGW37_RS14565	COG0163	prenyltransferase activity
FGW37_RS14575	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FGW37_RS14595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGW37_RS14600	COG1333	cytochrome c biogenesis protein
FGW37_RS14605	COG0785	Cytochrome C biogenesis protein
FGW37_RS14610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGW37_RS14620	COG0406	alpha-ribazole phosphatase activity
FGW37_RS14625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FGW37_RS14635	COG1742	UPF0060 membrane protein
FGW37_RS14655	COG1690	Belongs to the RtcB family
FGW37_RS14670	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FGW37_RS14675	COG0018	arginyl-trna synthetase
FGW37_RS14685	COG0113	porphobilinogen synthase activity
FGW37_RS14690	COG1648	precorrin-2 dehydrogenase activity
FGW37_RS14690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGW37_RS14695	COG0181	hydroxymethylbilane synthase activity
FGW37_RS14700	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FGW37_RS14705	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FGW37_RS14755	COG0123	including yeast histone deacetylase and acetoin utilization protein
FGW37_RS14760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGW37_RS14780	COG0180	Tryptophanyl-tRNA synthetase
FGW37_RS14785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FGW37_RS14790	COG0659	secondary active sulfate transmembrane transporter activity
FGW37_RS14795	COG1252	NADH dehydrogenase
FGW37_RS14820	COG1846	Transcriptional regulator
FGW37_RS14835	COG1252	NADH dehydrogenase
FGW37_RS14845	COG1470	cell adhesion involved in biofilm formation
FGW37_RS14845	COG0366	Alpha amylase catalytic
FGW37_RS14860	COG0579	oxidoreductase
FGW37_RS14865	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FGW37_RS14885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGW37_RS14940	COG0494	nUDIX hydrolase
FGW37_RS14950	COG0667	Aldo Keto reductase
FGW37_RS14970	COG1278	Cold shock
FGW37_RS14980	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FGW37_RS15020	COG1643	Atp-dependent helicase
FGW37_RS15055	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FGW37_RS15080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGW37_RS15085	COG0047	phosphoribosylformylglycinamidine synthase activity
FGW37_RS15090	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGW37_RS15130	COG3850	Histidine kinase
FGW37_RS15135	COG2197	response regulator
FGW37_RS15150	COG0745	RESPONSE REGULATOR receiver
FGW37_RS15155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGW37_RS15170	COG0151	Belongs to the GarS family
FGW37_RS15185	COG1802	Transcriptional regulator
FGW37_RS15195	COG1278	Cold shock
FGW37_RS15200	COG0515	serine threonine protein kinase
FGW37_RS15200	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGW37_RS15205	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FGW37_RS15215	COG2197	response regulator
FGW37_RS15220	COG4585	Histidine kinase
FGW37_RS15230	COG3844	kynureninase activity
FGW37_RS15235	COG3483	tryptophan 2,3-dioxygenase activity
FGW37_RS15245	COG0477	Major facilitator Superfamily
FGW37_RS15255	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGW37_RS15285	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FGW37_RS15310	COG0542	response to heat
FGW37_RS15365	COG2226	methyltransferase
FGW37_RS15385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FGW37_RS15395	COG1132	(ABC) transporter
FGW37_RS15405	COG2197	response regulator
FGW37_RS15425	COG0789	Transcriptional regulator
FGW37_RS15430	COG0484	heat shock protein binding
FGW37_RS15435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGW37_RS15440	COG0443	Heat shock 70 kDa protein
FGW37_RS15450	COG0247	lactate metabolic process
FGW37_RS15450	COG2181	nitrate reductase activity
FGW37_RS15470	COG0717	Belongs to the dCTP deaminase family
FGW37_RS15485	COG2815	serine threonine protein kinase
FGW37_RS15485	COG0515	serine threonine protein kinase
FGW37_RS15515	COG0477	Major facilitator Superfamily
FGW37_RS15600	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS15620	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS15655	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FGW37_RS15675	COG2205	protein histidine kinase activity
FGW37_RS15680	COG0745	RESPONSE REGULATOR receiver
FGW37_RS15730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGW37_RS15740	COG2318	DinB family
FGW37_RS15745	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FGW37_RS15755	COG1741	Belongs to the pirin family
FGW37_RS15770	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS15775	COG1362	aminopeptidase activity
FGW37_RS15805	COG2271	Major facilitator Superfamily
FGW37_RS15820	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGW37_RS15825	COG0022	dehydrogenase e1 component
FGW37_RS15850	COG0515	serine threonine protein kinase
FGW37_RS15855	COG0515	serine threonine protein kinase
FGW37_RS15870	COG0604	alcohol dehydrogenase
FGW37_RS15905	COG1522	sequence-specific DNA binding
FGW37_RS15910	COG1309	transcriptional regulator
FGW37_RS15915	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGW37_RS15940	COG3396	Phenylacetate-CoA oxygenase
FGW37_RS15945	COG3460	Phenylacetate-CoA oxygenase
FGW37_RS15950	COG3396	Phenylacetate-CoA oxygenase
FGW37_RS15955	COG2151	metal-sulfur cluster biosynthetic enzyme
FGW37_RS15960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGW37_RS15970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGW37_RS16000	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FGW37_RS16010	COG0646	methionine synthase
FGW37_RS16010	COG1410	methionine synthase
FGW37_RS16015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGW37_RS16020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGW37_RS16030	COG3321	synthase
FGW37_RS16030	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS16030	COG0604	alcohol dehydrogenase
FGW37_RS16035	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FGW37_RS16050	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FGW37_RS16060	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGW37_RS16070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FGW37_RS16085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGW37_RS16120	COG3629	intracellular signal transduction
FGW37_RS16195	COG1716	ATPase activity
FGW37_RS16200	COG1716	ATPase activity
FGW37_RS16215	COG0768	penicillin binding
FGW37_RS16220	COG0515	serine threonine protein kinase
FGW37_RS16225	COG3764	Sortase (surface protein transpeptidase)
FGW37_RS16230	COG3764	Sortase (surface protein transpeptidase)
FGW37_RS16245	COG3764	Sortase (surface protein transpeptidase)
FGW37_RS16260	COG0705	Rhomboid family
FGW37_RS16300	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS16320	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS16325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGW37_RS16330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGW37_RS16355	COG0515	serine threonine protein kinase
FGW37_RS16375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGW37_RS16385	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FGW37_RS16390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FGW37_RS16395	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FGW37_RS16400	COG0592	DNA-directed DNA polymerase activity
FGW37_RS16410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FGW37_RS16415	COG0594	ribonuclease P activity
FGW37_RS16420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FGW37_RS16425	COG0706	membrane insertase activity
FGW37_RS16435	COG0357	Ribosomal RNA small subunit methyltransferase G
FGW37_RS16440	COG1192	Involved in chromosome partitioning
FGW37_RS16455	COG3118	belongs to the thioredoxin family
FGW37_RS16460	COG0492	ferredoxin-NADP+ reductase activity
FGW37_RS16470	COG1595	DNA-templated transcription, initiation
FGW37_RS16475	COG2815	serine threonine protein kinase
FGW37_RS16475	COG0515	serine threonine protein kinase
FGW37_RS16490	COG0617	tRNA 3'-terminal CCA addition
FGW37_RS16500	COG1260	myo-inositol-1-phosphate synthase
FGW37_RS16510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGW37_RS16535	COG0360	Binds together with S18 to 16S ribosomal RNA
FGW37_RS16540	COG0629	single-stranded DNA binding
FGW37_RS16545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGW37_RS16550	COG0359	binds to the 23S rRNA
FGW37_RS16560	COG0305	Participates in initiation and elongation during chromosome replication
FGW37_RS16565	COG0667	Aldo Keto reductase
FGW37_RS16600	COG2814	Major facilitator Superfamily
FGW37_RS16630	COG0626	cystathionine gamma-synthase activity
FGW37_RS16635	COG1950	PFAM Membrane protein of
FGW37_RS16640	COG0662	Cupin 2, conserved barrel domain protein
FGW37_RS16655	COG2268	Band 7 protein
FGW37_RS16670	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FGW37_RS16685	COG1609	Transcriptional regulator
FGW37_RS16690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGW37_RS16695	COG1271	oxidase subunit
FGW37_RS16700	COG1294	oxidase, subunit
FGW37_RS16705	COG4988	ABC transporter
FGW37_RS16715	COG0739	heme binding
FGW37_RS16720	COG0561	phosphatase activity
FGW37_RS16730	COG0501	Belongs to the peptidase M48B family
FGW37_RS16740	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FGW37_RS16755	COG0789	Transcriptional regulator
FGW37_RS16775	COG1131	(ABC) transporter
FGW37_RS16795	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
FGW37_RS16800	COG2807	transmembrane transport
FGW37_RS16815	COG0561	phosphatase activity
FGW37_RS16820	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGW37_RS16825	COG0077	Prephenate dehydratase
FGW37_RS16830	COG2837	iron assimilation
FGW37_RS16835	COG2372	response to copper ion
FGW37_RS16845	COG1999	signal sequence binding
FGW37_RS16865	COG0640	Transcriptional regulator
FGW37_RS16885	COG0006	proline dipeptidase activity
FGW37_RS16905	COG0653	protein targeting
FGW37_RS16920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGW37_RS16955	COG0494	nUDIX hydrolase
FGW37_RS16960	COG0181	hydroxymethylbilane synthase activity
FGW37_RS16995	COG0477	Major facilitator Superfamily
FGW37_RS17005	COG1819	glycosyl
FGW37_RS17025	COG2890	protein-(glutamine-N5) methyltransferase activity
FGW37_RS17065	COG1595	DNA-templated transcription, initiation
FGW37_RS17070	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS17075	COG2814	Major facilitator Superfamily
FGW37_RS17080	COG1309	transcriptional regulator
FGW37_RS17085	COG0784	Response regulator, receiver
FGW37_RS17110	COG0745	RESPONSE REGULATOR receiver
FGW37_RS17130	COG0477	Major facilitator Superfamily
FGW37_RS17160	COG1191	sigma factor activity
FGW37_RS17245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FGW37_RS17260	COG0590	tRNA wobble adenosine to inosine editing
FGW37_RS17280	COG2814	Major facilitator Superfamily
FGW37_RS17285	COG0667	Aldo Keto reductase
FGW37_RS17310	COG1917	Cupin 2, conserved barrel domain protein
FGW37_RS17320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGW37_RS17345	COG1280	lysine exporter protein (LysE YggA)
FGW37_RS17360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGW37_RS17365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGW37_RS17375	COG1045	serine acetyltransferase
FGW37_RS17400	COG3708	Transcriptional regulator
FGW37_RS17400	COG2207	Transcriptional regulator
FGW37_RS17420	COG0745	RESPONSE REGULATOR receiver
FGW37_RS17425	COG0243	molybdopterin cofactor binding
FGW37_RS17430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGW37_RS17435	COG2146	nitrite reductase [NAD(P)H] activity
FGW37_RS17435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGW37_RS17440	COG2223	nitrite transmembrane transporter activity
FGW37_RS17535	COG2124	cytochrome p450
FGW37_RS17560	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FGW37_RS17565	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGW37_RS17590	COG1595	DNA-templated transcription, initiation
FGW37_RS17620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGW37_RS17625	COG2423	ornithine cyclodeaminase activity
FGW37_RS17655	COG1408	metallophosphoesterase
FGW37_RS17730	COG2267	carboxylic ester hydrolase activity
FGW37_RS17740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGW37_RS17745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGW37_RS17810	COG1111	helicase
FGW37_RS17810	COG1205	dead DEAH box helicase
FGW37_RS17815	COG1366	Belongs to the anti-sigma-factor antagonist family
FGW37_RS17825	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FGW37_RS17835	COG2890	protein-(glutamine-N5) methyltransferase activity
FGW37_RS17845	COG1754	DNA topoisomerase type I activity
FGW37_RS17845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGW37_RS17850	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FGW37_RS17855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FGW37_RS17890	COG0747	negative chemotaxis
FGW37_RS17905	COG4172	Belongs to the ABC transporter superfamily
FGW37_RS17910	COG0583	DNA-binding transcription factor activity
FGW37_RS17935	COG2124	cytochrome p450
FGW37_RS17955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGW37_RS17955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGW37_RS17965	COG2188	Transcriptional regulator
FGW37_RS17980	COG1309	transcriptional regulator
FGW37_RS18000	COG1309	transcriptional regulator
FGW37_RS18020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGW37_RS18025	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGW37_RS18030	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGW37_RS18035	COG0254	rRNA binding
FGW37_RS18045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGW37_RS18065	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS18070	COG2318	DinB family
FGW37_RS18100	COG0789	Transcriptional regulator
FGW37_RS18105	COG0393	Putative heavy-metal-binding
FGW37_RS18120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FGW37_RS18125	COG2027	D-alanyl-D-alanine carboxypeptidase
FGW37_RS18135	COG0037	tRNA processing
FGW37_RS18150	COG0302	gtp cyclohydrolase
FGW37_RS18160	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGW37_RS18160	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGW37_RS18175	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FGW37_RS18180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGW37_RS18195	COG1174	glycine betaine transport
FGW37_RS18200	COG1174	glycine betaine transport
FGW37_RS18215	COG0649	NAD binding
FGW37_RS18230	COG2197	response regulator
FGW37_RS18235	COG0640	Transcriptional regulator
FGW37_RS18250	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FGW37_RS18255	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FGW37_RS18265	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FGW37_RS18290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FGW37_RS18315	COG0741	lytic transglycosylase activity
FGW37_RS18315	COG0739	heme binding
FGW37_RS18315	COG1196	nuclear chromosome segregation
FGW37_RS18320	COG0346	lactoylglutathione lyase activity
FGW37_RS18325	COG2205	protein histidine kinase activity
FGW37_RS18330	COG0745	RESPONSE REGULATOR receiver
FGW37_RS18340	COG1595	DNA-templated transcription, initiation
FGW37_RS18350	COG4585	Histidine kinase
FGW37_RS18375	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FGW37_RS18395	COG0248	Ppx GppA phosphatase
FGW37_RS18400	COG1082	Xylose isomerase domain protein TIM barrel
FGW37_RS18410	COG0129	dihydroxy-acid dehydratase activity
FGW37_RS18415	COG0515	serine threonine protein kinase
FGW37_RS18415	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGW37_RS18445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGW37_RS18455	COG4585	Histidine kinase
FGW37_RS18460	COG2197	response regulator
FGW37_RS18470	COG1228	amidohydrolase
FGW37_RS18505	COG2815	serine threonine protein kinase
FGW37_RS18505	COG0515	serine threonine protein kinase
FGW37_RS18515	COG1196	nuclear chromosome segregation
FGW37_RS18515	COG0741	lytic transglycosylase activity
FGW37_RS18515	COG0739	heme binding
FGW37_RS18520	COG0671	phosphoesterase, PA-phosphatase related
FGW37_RS18525	COG0277	FAD linked oxidase domain protein
FGW37_RS18540	COG1937	Protein conserved in bacteria
FGW37_RS18550	COG0306	phosphate transporter
FGW37_RS18555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGW37_RS18600	COG0667	Aldo Keto reductase
FGW37_RS18610	COG1335	isochorismatase
FGW37_RS18630	COG4552	Acetyltransferase involved in intracellular survival and related
FGW37_RS18640	COG1490	D-aminoacyl-tRNA deacylase activity
FGW37_RS18645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGW37_RS18650	COG0735	belongs to the Fur family
FGW37_RS18660	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FGW37_RS18665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS18670	COG3485	protocatechuate 3,4-dioxygenase
FGW37_RS18695	COG2897	thiosulfate sulfurtransferase activity
FGW37_RS18730	COG0745	RESPONSE REGULATOR receiver
FGW37_RS18735	COG1609	Transcriptional regulator
FGW37_RS18765	COG2850	peptidyl-arginine hydroxylation
FGW37_RS18770	COG2850	peptidyl-arginine hydroxylation
FGW37_RS18775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGW37_RS18780	COG0745	RESPONSE REGULATOR receiver
FGW37_RS18795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGW37_RS18815	COG0737	Belongs to the 5'-nucleotidase family
FGW37_RS18820	COG0456	acetyltransferase
FGW37_RS18830	COG2409	Drug exporters of the RND superfamily
FGW37_RS18845	COG1725	Transcriptional regulator
FGW37_RS18850	COG1131	(ABC) transporter
FGW37_RS18855	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FGW37_RS18875	COG0438	transferase activity, transferring glycosyl groups
FGW37_RS18885	COG2211	Major facilitator Superfamily
FGW37_RS18890	COG0588	phosphoglycerate mutase activity
FGW37_RS18910	COG5002	protein histidine kinase activity
FGW37_RS18925	COG1329	Transcriptional regulator
FGW37_RS18930	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FGW37_RS18935	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FGW37_RS18950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FGW37_RS18955	COG0215	cysteine-tRNA ligase activity
FGW37_RS18970	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FGW37_RS18980	COG3842	ATPase activity
FGW37_RS18990	COG2409	Drug exporters of the RND superfamily
FGW37_RS19020	COG2197	response regulator
FGW37_RS19060	COG1683	Conserved Protein
FGW37_RS19080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGW37_RS19160	COG0463	Glycosyl transferase, family 2
FGW37_RS19185	COG1263	PTS System
FGW37_RS19185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGW37_RS19190	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FGW37_RS19195	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FGW37_RS19220	COG2814	Major facilitator Superfamily
FGW37_RS19225	COG0640	Transcriptional regulator
FGW37_RS19230	COG3973	AAA domain
FGW37_RS19245	COG1061	Type III restriction enzyme res subunit
FGW37_RS19300	COG2814	Major facilitator Superfamily
FGW37_RS19310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FGW37_RS19315	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FGW37_RS19320	COG1278	Cold shock
FGW37_RS19335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS19340	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS19345	COG1120	ATPase activity
FGW37_RS19350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGW37_RS19360	COG2353	YceI-like domain
FGW37_RS19390	COG2252	PERMEase
FGW37_RS19400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FGW37_RS19420	COG1846	Transcriptional regulator
FGW37_RS19435	COG0667	Aldo Keto reductase
FGW37_RS19460	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FGW37_RS19465	COG0247	lactate metabolic process
FGW37_RS19465	COG0277	FAD linked oxidase domain protein
FGW37_RS19475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGW37_RS19485	COG4770	biotin carboxylase activity
FGW37_RS19495	COG1024	Enoyl-CoA hydratase
FGW37_RS19510	COG0259	pyridoxamine-phosphate oxidase activity
FGW37_RS19520	COG4821	SIS domain
FGW37_RS19530	COG2945	thiolester hydrolase activity
FGW37_RS19530	COG0596	Alpha beta hydrolase
FGW37_RS19575	COG1366	Belongs to the anti-sigma-factor antagonist family
FGW37_RS19580	COG4585	Histidine kinase
FGW37_RS19585	COG2197	response regulator
FGW37_RS19655	COG2815	serine threonine protein kinase
FGW37_RS19655	COG0515	serine threonine protein kinase
FGW37_RS19665	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS19690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FGW37_RS19690	COG0519	Catalyzes the synthesis of GMP from XMP
FGW37_RS19710	COG1376	ErfK ybiS ycfS ynhG family protein
FGW37_RS19740	COG2197	response regulator
FGW37_RS19750	COG0791	NLP P60 protein
FGW37_RS19765	COG0739	heme binding
FGW37_RS19775	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGW37_RS19790	COG0714	Associated with various cellular activities
FGW37_RS19805	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FGW37_RS19810	COG0045	succinate-CoA ligase (ADP-forming) activity
FGW37_RS19835	COG0138	bifunctional purine biosynthesis protein purh
FGW37_RS19845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGW37_RS19855	COG0538	isocitrate dehydrogenase activity
FGW37_RS19865	COG0039	L-malate dehydrogenase activity
FGW37_RS19885	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS19895	COG0517	IMP dehydrogenase activity
FGW37_RS19895	COG4175	Glycine betaine
FGW37_RS19910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGW37_RS19915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGW37_RS19925	COG0754	glutathionylspermidine amidase activity
FGW37_RS19940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGW37_RS19945	COG0180	Tryptophanyl-tRNA synthetase
FGW37_RS19955	COG1295	ribonuclease BN
FGW37_RS19970	COG0747	negative chemotaxis
FGW37_RS19980	COG0789	Transcriptional regulator
FGW37_RS19985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FGW37_RS19990	COG1053	succinate dehydrogenase
FGW37_RS20000	COG2009	succinate dehydrogenase
FGW37_RS20025	COG1595	DNA-templated transcription, initiation
FGW37_RS20035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGW37_RS20035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGW37_RS20100	COG2186	Transcriptional regulator
FGW37_RS20105	COG3265	gluconokinase activity
FGW37_RS20130	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FGW37_RS20140	COG1216	Glycosyl transferase, family 2
FGW37_RS20155	COG2089	acid synthase
FGW37_RS20165	COG1473	amidohydrolase
FGW37_RS20165	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FGW37_RS20210	COG2814	Major facilitator Superfamily
FGW37_RS20215	COG0583	DNA-binding transcription factor activity
FGW37_RS20225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FGW37_RS20250	COG2205	protein histidine kinase activity
FGW37_RS20255	COG0745	RESPONSE REGULATOR receiver
FGW37_RS20260	COG1595	DNA-templated transcription, initiation
FGW37_RS20275	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS20280	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS20285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FGW37_RS20295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGW37_RS20335	COG4770	biotin carboxylase activity
FGW37_RS20375	COG0424	maF-like protein
FGW37_RS20380	COG0768	penicillin binding
FGW37_RS20395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGW37_RS20405	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FGW37_RS20420	COG2986	histidine ammonia-lyase
FGW37_RS20450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGW37_RS20470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGW37_RS20490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGW37_RS20510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FGW37_RS20525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGW37_RS20535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FGW37_RS20545	COG1331	Highly conserved protein containing a thioredoxin domain
FGW37_RS20555	COG0477	Major facilitator Superfamily
FGW37_RS20565	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FGW37_RS20580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FGW37_RS20595	COG1414	Transcriptional regulator
FGW37_RS20600	COG0251	oxidation-reduction process
FGW37_RS20605	COG2610	gluconate transmembrane transporter activity
FGW37_RS20655	COG2894	cell division
FGW37_RS20685	COG3850	Histidine kinase
FGW37_RS20690	COG2197	response regulator
FGW37_RS20710	COG2885	chlorophyll binding
FGW37_RS20750	COG2814	Major facilitator Superfamily
FGW37_RS20755	COG0667	Aldo Keto reductase
FGW37_RS20760	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGW37_RS20765	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FGW37_RS20780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGW37_RS20785	COG0450	alkyl hydroperoxide reductase
FGW37_RS20800	COG1136	(ABC) transporter
FGW37_RS20810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGW37_RS20825	COG2226	methyltransferase
FGW37_RS20835	COG0114	fumarate hydratase activity
FGW37_RS20845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FGW37_RS20845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FGW37_RS20870	COG0778	Nitroreductase
FGW37_RS20875	COG1722	exodeoxyribonuclease VII activity
FGW37_RS20880	COG1570	exodeoxyribonuclease VII activity
FGW37_RS20890	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FGW37_RS20905	COG0012	GTP binding
FGW37_RS20920	COG0531	amino acid
FGW37_RS21005	COG0601	transmembrane transport
FGW37_RS21020	COG4608	Belongs to the ABC transporter superfamily
FGW37_RS21030	COG0601	transmembrane transport
FGW37_RS21035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGW37_RS21045	COG4608	Belongs to the ABC transporter superfamily
FGW37_RS21050	COG4608	Belongs to the ABC transporter superfamily
FGW37_RS21060	COG0601	transmembrane transport
FGW37_RS21065	COG4166	transmembrane transport
FGW37_RS21085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FGW37_RS21100	COG1131	(ABC) transporter
FGW37_RS21110	COG4585	Histidine kinase
FGW37_RS21150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGW37_RS21160	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FGW37_RS21170	COG0519	Catalyzes the synthesis of GMP from XMP
FGW37_RS21175	COG1024	Enoyl-CoA hydratase
FGW37_RS21190	COG1595	DNA-templated transcription, initiation
FGW37_RS21200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGW37_RS21205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGW37_RS21215	COG3422	double-strand break repair
FGW37_RS21250	COG0598	Magnesium transport protein CorA
FGW37_RS21270	COG2095	MarC family integral membrane protein
FGW37_RS21280	COG1432	Conserved Protein
FGW37_RS21295	COG0513	Belongs to the DEAD box helicase family
FGW37_RS21340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGW37_RS21390	COG0596	Alpha beta hydrolase
FGW37_RS21430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGW37_RS21470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FGW37_RS21525	COG3480	Lon protease (S16) C-terminal proteolytic domain
FGW37_RS21535	COG1615	UPF0182 protein
FGW37_RS21560	COG0753	catalase activity
FGW37_RS21570	COG0483	inositol monophosphate 1-phosphatase activity
FGW37_RS21580	COG2076	Multidrug Resistance protein
FGW37_RS21590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FGW37_RS21600	COG2135	peptidase activity
FGW37_RS21610	COG1595	DNA-templated transcription, initiation
FGW37_RS21620	COG2199	diguanylate cyclase activity
FGW37_RS21620	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGW37_RS21635	COG0242	peptide deformylase activity
FGW37_RS21645	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGW37_RS21665	COG0673	inositol 2-dehydrogenase activity
FGW37_RS21675	COG0659	secondary active sulfate transmembrane transporter activity
FGW37_RS21695	COG0477	Major facilitator Superfamily
FGW37_RS21700	COG2188	Transcriptional regulator
FGW37_RS21705	COG2182	Extracellular solute-binding protein
FGW37_RS21710	COG1175	transmembrane transport
FGW37_RS21715	COG0395	ABC-type sugar transport system, permease component
FGW37_RS21720	COG1472	Belongs to the glycosyl hydrolase 3 family
FGW37_RS21725	COG0363	glucosamine-6-phosphate deaminase activity
FGW37_RS21730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGW37_RS21735	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS21740	COG1309	transcriptional regulator
FGW37_RS21755	COG1597	lipid kinase activity
FGW37_RS21800	COG2066	Belongs to the glutaminase family
FGW37_RS21805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGW37_RS21815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGW37_RS21830	COG0745	RESPONSE REGULATOR receiver
FGW37_RS21845	COG0583	DNA-binding transcription factor activity
FGW37_RS21850	COG2814	Major facilitator Superfamily
FGW37_RS21860	COG1191	sigma factor activity
FGW37_RS21875	COG0640	Transcriptional regulator
FGW37_RS21900	COG4106	trans-aconitate 2-methyltransferase activity
FGW37_RS21910	COG0604	alcohol dehydrogenase
FGW37_RS21915	COG0281	malic enzyme
FGW37_RS21925	COG0765	amino acid transport
FGW37_RS21930	COG1126	abc transporter atp-binding protein
FGW37_RS21970	COG0567	Dehydrogenase, E1 component
FGW37_RS21970	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGW37_RS21975	COG2205	protein histidine kinase activity
FGW37_RS21980	COG0745	RESPONSE REGULATOR receiver
FGW37_RS21995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGW37_RS22000	COG3708	Transcriptional regulator
FGW37_RS22000	COG2207	Transcriptional regulator
FGW37_RS22005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FGW37_RS22010	COG1846	Transcriptional regulator
FGW37_RS22020	COG3227	Zinc metalloprotease (Elastase)
FGW37_RS22065	COG0791	NLP P60 protein
FGW37_RS22180	COG2188	Transcriptional regulator
FGW37_RS22255	COG0019	diaminopimelate decarboxylase activity
FGW37_RS22260	COG0460	homoserine dehydrogenase
FGW37_RS22265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FGW37_RS22270	COG0083	homoserine kinase activity
FGW37_RS22285	COG0254	rRNA binding
FGW37_RS22290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGW37_RS22295	COG2890	protein-(glutamine-N5) methyltransferase activity
FGW37_RS22305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGW37_RS22310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGW37_RS22315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGW37_RS22330	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGW37_RS22335	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGW37_RS22340	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGW37_RS22345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGW37_RS22350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGW37_RS22355	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGW37_RS22360	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FGW37_RS22375	COG2197	response regulator
FGW37_RS22380	COG4585	Histidine kinase
FGW37_RS22395	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGW37_RS22410	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FGW37_RS22470	COG0183	Belongs to the thiolase family
FGW37_RS22480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGW37_RS22520	COG2161	toxin-antitoxin pair type II binding
FGW37_RS22550	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGW37_RS22550	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGW37_RS22585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGW37_RS22590	COG0280	phosphate acetyltransferase
FGW37_RS22590	COG0857	belongs to the CobB CobQ family
FGW37_RS22595	COG0205	6-phosphofructokinase activity
FGW37_RS22615	COG1136	(ABC) transporter
FGW37_RS22615	COG0577	efflux transmembrane transporter activity
FGW37_RS22620	COG1136	(ABC) transporter
FGW37_RS22620	COG0577	efflux transmembrane transporter activity
FGW37_RS22625	COG0395	ABC-type sugar transport system, permease component
FGW37_RS22640	COG1175	transmembrane transport
FGW37_RS22650	COG4565	transcriptional regulatory protein
FGW37_RS22655	COG3290	protein histidine kinase activity
FGW37_RS22660	COG1301	dicarboxylic acid transport
FGW37_RS22695	COG0477	Major facilitator Superfamily
FGW37_RS22700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FGW37_RS22705	COG3281	Trehalose synthase
FGW37_RS22710	COG0366	Alpha amylase catalytic
FGW37_RS22715	COG0366	Alpha amylase catalytic
FGW37_RS22720	COG0058	SHG alpha-glucan phosphorylase activity
FGW37_RS22730	COG1132	(ABC) transporter
FGW37_RS22735	COG1132	(ABC) transporter
FGW37_RS22745	COG1376	ErfK ybiS ycfS ynhG family protein
FGW37_RS22785	COG1760	l-serine dehydratase
FGW37_RS22790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGW37_RS22795	COG0509	glycine decarboxylation via glycine cleavage system
FGW37_RS22800	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGW37_RS22825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGW37_RS22830	COG4166	transmembrane transport
FGW37_RS22840	COG0444	Belongs to the ABC transporter superfamily
FGW37_RS22845	COG4608	Belongs to the ABC transporter superfamily
FGW37_RS22850	COG2860	membrane
FGW37_RS22865	COG2378	regulation of single-species biofilm formation
FGW37_RS22880	COG0482	sulfurtransferase activity
FGW37_RS22890	COG1611	Belongs to the LOG family
FGW37_RS22895	COG4221	oxidoreductase activity
FGW37_RS22900	COG1846	Transcriptional regulator
FGW37_RS22915	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGW37_RS22925	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGW37_RS22930	COG0154	amidase activity
FGW37_RS22940	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGW37_RS22950	COG2409	Drug exporters of the RND superfamily
FGW37_RS22960	COG2133	pyrroloquinoline quinone binding
FGW37_RS22965	COG0667	Aldo Keto reductase
FGW37_RS22985	COG0440	acetolactate synthase activity
FGW37_RS22990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FGW37_RS22995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGW37_RS23005	COG0477	Major facilitator Superfamily
FGW37_RS23015	COG2124	cytochrome p450
FGW37_RS23030	COG0506	proline dehydrogenase activity
FGW37_RS23035	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS23040	COG0204	Acyl-transferase
FGW37_RS23065	COG0473	3-isopropylmalate dehydrogenase activity
FGW37_RS23070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGW37_RS23075	COG0477	Major facilitator Superfamily
FGW37_RS23080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGW37_RS23095	COG2353	YceI-like domain
FGW37_RS23100	COG5492	domain, Protein
FGW37_RS23105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGW37_RS23125	COG2018	Roadblock/LC7 domain
FGW37_RS23145	COG2018	Roadblock/LC7 domain
FGW37_RS23160	COG0179	Fumarylacetoacetate (FAA) hydrolase
FGW37_RS23165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGW37_RS23215	COG1414	Transcriptional regulator
FGW37_RS23220	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGW37_RS23225	COG0066	3-isopropylmalate dehydratase activity
FGW37_RS23235	COG0776	regulation of translation
FGW37_RS23245	COG1920	GTP binding
FGW37_RS23255	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGW37_RS23260	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGW37_RS23280	COG0351	phosphomethylpyrimidine kinase
FGW37_RS23285	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGW37_RS23290	COG1461	Dihydroxyacetone kinase
FGW37_RS23300	COG0742	ribosomal rna small subunit methyltransferase
FGW37_RS23305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGW37_RS23320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FGW37_RS23325	COG0571	ribonuclease III activity
FGW37_RS23330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGW37_RS23335	COG1733	regulation of RNA biosynthetic process
FGW37_RS23350	COG1254	Belongs to the acylphosphatase family
FGW37_RS23360	COG1196	nuclear chromosome segregation
FGW37_RS23365	COG0477	Major facilitator Superfamily
FGW37_RS23400	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FGW37_RS23415	COG0442	prolyl-tRNA aminoacylation
FGW37_RS23425	COG0228	four-way junction DNA binding
FGW37_RS23430	COG1837	Belongs to the UPF0109 family
FGW37_RS23435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGW37_RS23440	COG0336	Belongs to the RNA methyltransferase TrmD family
FGW37_RS23445	COG0335	large ribosomal subunit rRNA binding
FGW37_RS23455	COG0681	Belongs to the peptidase S26 family
FGW37_RS23460	COG0681	Belongs to the peptidase S26 family
FGW37_RS23480	COG0792	nuclease activity
FGW37_RS23495	COG1191	sigma factor activity
FGW37_RS23510	COG0052	Belongs to the universal ribosomal protein uS2 family
FGW37_RS23515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGW37_RS23520	COG0528	UMP kinase activity
FGW37_RS23525	COG0233	cytoplasmic translational termination
FGW37_RS23535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FGW37_RS23550	COG3842	ATPase activity
FGW37_RS23570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FGW37_RS23580	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS23595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FGW37_RS23615	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS23630	COG3842	ATPase activity
FGW37_RS23635	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGW37_RS23640	COG1177	transmembrane transport
FGW37_RS23645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGW37_RS23670	COG2508	Transcriptional regulator
FGW37_RS23690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FGW37_RS23695	COG0750	zinc metalloprotease
FGW37_RS23700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FGW37_RS23715	COG0442	prolyl-tRNA aminoacylation
FGW37_RS23735	COG0779	Required for maturation of 30S ribosomal subunits
FGW37_RS23750	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGW37_RS23760	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGW37_RS23765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGW37_RS23780	COG0455	bacterial-type flagellum organization
FGW37_RS23800	COG1404	Belongs to the peptidase S8 family
FGW37_RS23820	COG1674	ftsk spoiiie
FGW37_RS23830	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGW37_RS23835	COG1185	polyribonucleotide nucleotidyltransferase activity
FGW37_RS23840	COG0612	Peptidase, M16
FGW37_RS23845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FGW37_RS23865	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FGW37_RS23870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGW37_RS23875	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FGW37_RS23905	COG2208	phosphoserine phosphatase activity
FGW37_RS23905	COG2770	Histidine kinase
FGW37_RS23910	COG2205	protein histidine kinase activity
FGW37_RS23910	COG3437	response regulator, receiver
FGW37_RS23910	COG3850	Histidine kinase
FGW37_RS23910	COG4999	Histidine kinase
FGW37_RS23920	COG1674	ftsk spoiiie
FGW37_RS23930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGW37_RS23940	COG1546	Belongs to the CinA family
FGW37_RS23940	COG1058	Belongs to the CinA family
FGW37_RS23945	COG1396	sequence-specific DNA binding
FGW37_RS23965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGW37_RS23970	COG1201	RNA secondary structure unwinding
FGW37_RS23990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGW37_RS24015	COG0765	amino acid transport
FGW37_RS24020	COG0765	amino acid transport
FGW37_RS24030	COG1126	abc transporter atp-binding protein
FGW37_RS24040	COG2205	protein histidine kinase activity
FGW37_RS24050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGW37_RS24070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGW37_RS24080	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FGW37_RS24085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGW37_RS24095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FGW37_RS24170	COG0488	(ABC) transporter
FGW37_RS24175	COG0588	phosphoglycerate mutase activity
FGW37_RS24185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGW37_RS24225	COG2186	Transcriptional regulator
FGW37_RS24230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGW37_RS24245	COG0187	DNA topoisomerase II activity
FGW37_RS24250	COG4565	transcriptional regulatory protein
FGW37_RS24255	COG3290	protein histidine kinase activity
FGW37_RS24265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGW37_RS24285	COG0372	Belongs to the citrate synthase family
FGW37_RS24295	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGW37_RS24300	COG0612	Peptidase, M16
FGW37_RS24315	COG1802	Transcriptional regulator
FGW37_RS24320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGW37_RS24325	COG1042	CoA-binding domain protein
FGW37_RS24325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGW37_RS24325	COG0045	succinate-CoA ligase (ADP-forming) activity
FGW37_RS24340	COG1435	thymidine kinase activity
FGW37_RS24380	COG0483	inositol monophosphate 1-phosphatase activity
FGW37_RS24390	COG0745	RESPONSE REGULATOR receiver
FGW37_RS24395	COG2205	protein histidine kinase activity
FGW37_RS24420	COG0756	dUTP diphosphatase activity
FGW37_RS24435	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FGW37_RS24440	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FGW37_RS24445	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FGW37_RS24485	COG0569	domain protein
FGW37_RS24500	COG2264	protein methyltransferase activity
FGW37_RS24510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGW37_RS24535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGW37_RS24545	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FGW37_RS24550	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS24615	COG0531	amino acid
FGW37_RS24620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGW37_RS24635	COG1201	RNA secondary structure unwinding
FGW37_RS24705	COG0515	serine threonine protein kinase
FGW37_RS24705	COG2815	serine threonine protein kinase
FGW37_RS24730	COG1215	transferase activity, transferring glycosyl groups
FGW37_RS24730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FGW37_RS24740	COG1799	cell septum assembly
FGW37_RS24770	COG2040	homocysteine
FGW37_RS24790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FGW37_RS24805	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS24825	COG1024	Enoyl-CoA hydratase
FGW37_RS24830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGW37_RS24835	COG2235	arginine
FGW37_RS24840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGW37_RS24850	COG0596	Alpha beta hydrolase
FGW37_RS24855	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FGW37_RS24920	COG1653	transport
FGW37_RS24925	COG1175	transmembrane transport
FGW37_RS24930	COG0395	ABC-type sugar transport system, permease component
FGW37_RS24975	COG1940	carbohydrate kinase activity
FGW37_RS24980	COG4213	ABC transporter substrate-binding protein
FGW37_RS24990	COG4214	carbohydrate transport
FGW37_RS24995	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FGW37_RS25000	COG0531	amino acid
FGW37_RS25025	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGW37_RS25050	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FGW37_RS25080	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGW37_RS25080	COG1024	Enoyl-CoA hydratase
FGW37_RS25105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FGW37_RS25130	COG2226	methyltransferase
FGW37_RS25140	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGW37_RS25145	COG3485	protocatechuate 3,4-dioxygenase
FGW37_RS25150	COG3485	protocatechuate 3,4-dioxygenase
FGW37_RS25160	COG0183	Belongs to the thiolase family
FGW37_RS25205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGW37_RS25220	COG1136	(ABC) transporter
FGW37_RS25260	COG1136	(ABC) transporter
FGW37_RS25265	COG0577	efflux transmembrane transporter activity
FGW37_RS25270	COG4585	Histidine kinase
FGW37_RS25275	COG2197	response regulator
FGW37_RS25280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGW37_RS25285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGW37_RS25300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGW37_RS25305	COG0583	DNA-binding transcription factor activity
FGW37_RS25345	COG1846	Transcriptional regulator
FGW37_RS25355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGW37_RS25360	COG1116	anion transmembrane transporter activity
FGW37_RS25380	COG0529	Catalyzes the synthesis of activated sulfate
FGW37_RS25385	COG0175	sulfate reduction
FGW37_RS25415	COG1162	GTPase activity
FGW37_RS25425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGW37_RS25460	COG1802	Transcriptional regulator
FGW37_RS25480	COG2252	PERMEase
FGW37_RS25485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGW37_RS25520	COG1285	pathogenesis
FGW37_RS25540	COG2274	protein secretion by the type I secretion system
FGW37_RS25555	COG0598	Magnesium transport protein CorA
FGW37_RS25575	COG2197	response regulator
FGW37_RS25580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGW37_RS25585	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS25595	COG3960	tartronate-semialdehyde synthase activity
FGW37_RS25600	COG2084	Dehydrogenase
FGW37_RS25605	COG3622	Belongs to the hyi family
FGW37_RS25620	COG0789	Transcriptional regulator
FGW37_RS25630	COG2351	hydroxyisourate hydrolase activity
FGW37_RS25645	COG2233	PERMEase
FGW37_RS25650	COG1288	antiporter activity
FGW37_RS25670	COG1414	Transcriptional regulator
FGW37_RS25675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FGW37_RS25680	COG4266	Belongs to the allantoicase family
FGW37_RS25725	COG2188	Transcriptional regulator
FGW37_RS25745	COG1940	carbohydrate kinase activity
FGW37_RS25800	COG0667	Aldo Keto reductase
FGW37_RS25880	COG0436	Aminotransferase
FGW37_RS25890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGW37_RS25905	COG0492	ferredoxin-NADP+ reductase activity
FGW37_RS25925	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS25930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FGW37_RS25935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FGW37_RS25990	COG1126	abc transporter atp-binding protein
FGW37_RS25995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGW37_RS26000	COG0765	amino acid transport
FGW37_RS26005	COG0765	amino acid transport
FGW37_RS26010	COG3794	PFAM blue (type 1) copper domain protein
FGW37_RS26015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGW37_RS26015	COG1017	nitric oxide dioxygenase activity
FGW37_RS26020	COG1959	2 iron, 2 sulfur cluster binding
FGW37_RS26025	COG2755	lipolytic protein G-D-S-L family
FGW37_RS26030	COG0405	Gamma-glutamyltransferase
FGW37_RS26040	COG1335	isochorismatase
FGW37_RS26045	COG2814	Major facilitator Superfamily
FGW37_RS26060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGW37_RS26065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FGW37_RS26075	COG0095	Lipoate-protein ligase
FGW37_RS26085	COG0483	inositol monophosphate 1-phosphatase activity
FGW37_RS26095	COG0542	response to heat
FGW37_RS26120	COG1309	transcriptional regulator
FGW37_RS26125	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS26130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FGW37_RS26135	COG1929	Belongs to the glycerate kinase type-1 family
FGW37_RS26145	COG0688	phosphatidylethanolamine metabolic process
FGW37_RS26150	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS26160	COG2301	Belongs to the HpcH HpaI aldolase family
FGW37_RS26165	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGW37_RS26165	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGW37_RS26180	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGW37_RS26200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGW37_RS26230	COG2814	Major facilitator Superfamily
FGW37_RS26235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FGW37_RS26250	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS26260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS26270	COG2362	D-Aminopeptidase
FGW37_RS26275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGW37_RS26285	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS26290	COG1169	isochorismate synthase
FGW37_RS26295	COG1021	2,3-dihydroxybenzoate-AMP ligase
FGW37_RS26300	COG3433	isochorismatase activity
FGW37_RS26300	COG1535	isochorismatase
FGW37_RS26305	COG3433	isochorismatase activity
FGW37_RS26305	COG1535	isochorismatase
FGW37_RS26310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS26310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS26350	COG1309	transcriptional regulator
FGW37_RS26355	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS26360	COG0531	amino acid
FGW37_RS26405	COG2154	pterin-4-alpha-carbinolamine dehydratase
FGW37_RS26415	COG0656	L-ascorbic acid biosynthetic process
FGW37_RS26425	COG0583	DNA-binding transcription factor activity
FGW37_RS26445	COG1846	Transcriptional regulator
FGW37_RS26450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FGW37_RS26520	COG2890	protein-(glutamine-N5) methyltransferase activity
FGW37_RS26530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGW37_RS26545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS26550	COG0156	8-amino-7-oxononanoate synthase activity
FGW37_RS26555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGW37_RS26560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGW37_RS26565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGW37_RS26570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGW37_RS26590	COG2197	response regulator
FGW37_RS26600	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS26605	COG3321	synthase
FGW37_RS26610	COG3629	intracellular signal transduction
FGW37_RS26615	COG2197	response regulator
FGW37_RS26620	COG4585	Histidine kinase
FGW37_RS26625	COG2409	Drug exporters of the RND superfamily
FGW37_RS26635	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FGW37_RS26660	COG1515	deoxyribonuclease V activity
FGW37_RS26665	COG2936	dipeptidyl-peptidase activity
FGW37_RS26675	COG0789	Transcriptional regulator
FGW37_RS26680	COG1024	Enoyl-CoA hydratase
FGW37_RS26680	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGW37_RS26685	COG0183	Belongs to the thiolase family
FGW37_RS26690	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS26695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FGW37_RS26705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGW37_RS26715	COG0488	(ABC) transporter
FGW37_RS26720	COG2183	response to ionizing radiation
FGW37_RS26745	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FGW37_RS26790	COG1134	teichoic acid transport
FGW37_RS26790	COG1388	LysM domain
FGW37_RS26795	COG1562	ergosterol biosynthetic process
FGW37_RS26805	COG1233	COG1233 Phytoene dehydrogenase and related
FGW37_RS26815	COG1657	PFAM Prenyltransferase squalene oxidase
FGW37_RS26830	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FGW37_RS26835	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FGW37_RS26850	COG2755	lipolytic protein G-D-S-L family
FGW37_RS26890	COG1228	amidohydrolase
FGW37_RS26935	COG2226	methyltransferase
FGW37_RS26940	COG2207	Transcriptional regulator
FGW37_RS26945	COG2223	nitrite transmembrane transporter activity
FGW37_RS26955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGW37_RS26965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS26965	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FGW37_RS26995	COG2223	nitrite transmembrane transporter activity
FGW37_RS27000	COG0243	molybdopterin cofactor binding
FGW37_RS27005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGW37_RS27010	COG0431	NADPH-dependent FMN reductase
FGW37_RS27020	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGW37_RS27020	COG1902	pentaerythritol trinitrate reductase activity
FGW37_RS27050	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FGW37_RS27060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGW37_RS27065	COG2860	membrane
FGW37_RS27070	COG0235	Class ii aldolase
FGW37_RS27075	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FGW37_RS27080	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FGW37_RS27090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGW37_RS27100	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS27130	COG1773	rubredoxin
FGW37_RS27135	COG2124	cytochrome p450
FGW37_RS27165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGW37_RS27225	COG1120	ATPase activity
FGW37_RS27230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGW37_RS27240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS27250	COG0477	Major facilitator Superfamily
FGW37_RS27255	COG2382	esterase
FGW37_RS27260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS27285	COG1132	(ABC) transporter
FGW37_RS27315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGW37_RS27320	COG1879	ABC-type sugar transport system periplasmic component
FGW37_RS27325	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGW37_RS27330	COG1129	ABC transporter
FGW37_RS27335	COG1609	Transcriptional regulator
FGW37_RS27340	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FGW37_RS27385	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FGW37_RS27415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGW37_RS27465	COG3903	Transcriptional regulator
FGW37_RS27465	COG3629	intracellular signal transduction
FGW37_RS27510	COG0531	amino acid
FGW37_RS27525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGW37_RS27540	COG4948	Mandelate Racemase Muconate Lactonizing
FGW37_RS27605	COG4585	Histidine kinase
FGW37_RS27610	COG2197	response regulator
FGW37_RS27615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGW37_RS27620	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGW37_RS27625	COG0531	amino acid
FGW37_RS27630	COG3537	Alpha-1,2-mannosidase
FGW37_RS27655	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FGW37_RS27660	COG0121	glutamine amidotransferase
FGW37_RS27665	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FGW37_RS27690	COG1024	Enoyl-CoA hydratase
FGW37_RS27695	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS27710	COG3360	Dodecin
FGW37_RS27715	COG0745	RESPONSE REGULATOR receiver
FGW37_RS27720	COG2205	protein histidine kinase activity
FGW37_RS27750	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS27755	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS27760	COG1024	Enoyl-CoA hydratase
FGW37_RS27765	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS27770	COG1309	transcriptional regulator
FGW37_RS27775	COG0183	Belongs to the thiolase family
FGW37_RS27805	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS27815	COG1131	(ABC) transporter
FGW37_RS27845	COG0395	ABC-type sugar transport system, permease component
FGW37_RS27850	COG1175	transmembrane transport
FGW37_RS27860	COG1609	Transcriptional regulator
FGW37_RS27875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGW37_RS27880	COG0444	Belongs to the ABC transporter superfamily
FGW37_RS27885	COG1124	(ABC) transporter
FGW37_RS27890	COG0697	spore germination
FGW37_RS27905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGW37_RS27910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGW37_RS27930	COG2353	YceI-like domain
FGW37_RS27940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGW37_RS27965	COG3511	phospholipase C
FGW37_RS27995	COG2018	Roadblock/LC7 domain
FGW37_RS28005	COG1946	Acyl-CoA thioesterase
FGW37_RS28020	COG1132	(ABC) transporter
FGW37_RS28035	COG1846	Transcriptional regulator
FGW37_RS28040	COG1132	(ABC) transporter
FGW37_RS28045	COG0477	Major facilitator Superfamily
FGW37_RS28055	COG1556	Lactate utilization protein
FGW37_RS28060	COG1139	Iron-sulfur cluster binding protein
FGW37_RS28065	COG0247	lactate metabolic process
FGW37_RS28070	COG2072	flavoprotein involved in K transport
FGW37_RS28075	COG0432	Pfam Uncharacterised protein family UPF0047
FGW37_RS28085	COG1522	sequence-specific DNA binding
FGW37_RS28090	COG4172	Belongs to the ABC transporter superfamily
FGW37_RS28095	COG4171	peptide transport system, permease
FGW37_RS28100	COG0601	transmembrane transport
FGW37_RS28105	COG4166	transmembrane transport
FGW37_RS28120	COG0019	diaminopimelate decarboxylase activity
FGW37_RS28125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGW37_RS28130	COG0534	Mate efflux family protein
FGW37_RS28140	COG2807	transmembrane transport
FGW37_RS28150	COG0753	catalase activity
FGW37_RS28155	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FGW37_RS28160	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS28160	COG2030	dehydratase
FGW37_RS28170	COG0736	holo-[acyl-carrier-protein] synthase activity
FGW37_RS28185	COG0583	DNA-binding transcription factor activity
FGW37_RS28195	COG2706	6-phosphogluconolactonase activity
FGW37_RS28210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGW37_RS28215	COG1902	pentaerythritol trinitrate reductase activity
FGW37_RS28220	COG0640	Transcriptional regulator
FGW37_RS28230	COG1309	transcriptional regulator
FGW37_RS28235	COG0546	phosphoglycolate phosphatase activity
FGW37_RS28245	COG0671	phosphoesterase, PA-phosphatase related
FGW37_RS28270	COG0765	amino acid transport
FGW37_RS28275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGW37_RS28315	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FGW37_RS28360	COG2223	nitrite transmembrane transporter activity
FGW37_RS28365	COG1940	carbohydrate kinase activity
FGW37_RS28395	COG1349	DNA-binding transcription factor activity
FGW37_RS28405	COG0464	growth
FGW37_RS28425	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FGW37_RS28470	COG1404	Belongs to the peptidase S8 family
FGW37_RS28510	COG0531	amino acid
FGW37_RS28515	COG1113	amino acid transport
FGW37_RS28570	COG1215	transferase activity, transferring glycosyl groups
FGW37_RS28575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FGW37_RS28585	COG1051	belongs to the nudix hydrolase family
FGW37_RS28590	COG0583	DNA-binding transcription factor activity
FGW37_RS28595	COG0586	Pfam SNARE associated Golgi protein
FGW37_RS28610	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS28615	COG1132	(ABC) transporter
FGW37_RS28625	COG1027	Aspartate ammonia-lyase
FGW37_RS28630	COG0252	asparaginase activity
FGW37_RS28640	COG0346	lactoylglutathione lyase activity
FGW37_RS28690	COG1222	aaa ATPase
FGW37_RS28755	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FGW37_RS28795	COG2272	Belongs to the type-B carboxylesterase lipase family
FGW37_RS28800	COG3226	Transcriptional regulator
FGW37_RS28820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGW37_RS28825	COG1982	Orn Lys Arg decarboxylase major
FGW37_RS28840	COG1309	transcriptional regulator
FGW37_RS28855	COG1028	Short-chain dehydrogenase reductase Sdr
FGW37_RS28870	COG2124	cytochrome p450
FGW37_RS28875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FGW37_RS28880	COG4977	sequence-specific DNA binding
FGW37_RS28880	COG1917	Cupin 2, conserved barrel domain protein
FGW37_RS28885	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FGW37_RS28890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGW37_RS28895	COG0798	PFAM Bile acid sodium symporter
FGW37_RS28900	COG0640	Transcriptional regulator
FGW37_RS28920	COG0531	amino acid
FGW37_RS28960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGW37_RS28995	COG3268	Saccharopine dehydrogenase
FGW37_RS29025	COG0300	oxidoreductase activity
FGW37_RS29045	COG1032	radical SAM domain protein
FGW37_RS29070	COG4585	Histidine kinase
FGW37_RS29075	COG2197	response regulator
FGW37_RS29085	COG2124	cytochrome p450
FGW37_RS29090	COG1764	response to oxidative stress
FGW37_RS29095	COG1846	Transcriptional regulator
FGW37_RS29115	COG0583	DNA-binding transcription factor activity
FGW37_RS29125	COG0488	(ABC) transporter
FGW37_RS29130	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FGW37_RS29140	COG0387	Pfam Sodium calcium exchanger
FGW37_RS29160	COG1414	Transcriptional regulator
FGW37_RS29165	COG2124	cytochrome p450
FGW37_RS29185	COG3903	Transcriptional regulator
FGW37_RS29185	COG3629	intracellular signal transduction
FGW37_RS29205	COG0367	asparagine synthase
FGW37_RS29220	COG3634	alkyl hydroperoxide reductase activity
FGW37_RS29275	COG1132	(ABC) transporter
FGW37_RS29300	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGW37_RS29305	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FGW37_RS29310	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGW37_RS29315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGW37_RS29320	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FGW37_RS29325	COG3433	isochorismatase activity
FGW37_RS29325	COG1535	isochorismatase
FGW37_RS29330	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FGW37_RS29355	COG1132	(ABC) transporter
FGW37_RS29360	COG2375	cellular response to nickel ion
FGW37_RS29365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS29370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGW37_RS29395	COG3290	protein histidine kinase activity
FGW37_RS29400	COG3511	phospholipase C
FGW37_RS29415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FGW37_RS29415	COG1796	DNA polymerase
FGW37_RS29420	COG5504	Zn-dependent protease
FGW37_RS29430	COG1132	(ABC) transporter
FGW37_RS29450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FGW37_RS29460	COG2409	Drug exporters of the RND superfamily
FGW37_RS29505	COG0477	Major facilitator Superfamily
FGW37_RS29510	COG0515	serine threonine protein kinase
FGW37_RS29515	COG0515	serine threonine protein kinase
FGW37_RS29545	COG2376	Dihydroxyacetone kinase
FGW37_RS29635	COG2815	serine threonine protein kinase
FGW37_RS29635	COG0515	serine threonine protein kinase
FGW37_RS29770	COG4977	sequence-specific DNA binding
FGW37_RS29855	COG2226	methyltransferase
FGW37_RS29865	COG2188	Transcriptional regulator
FGW37_RS29980	COG1554	hydrolase, family 65, central catalytic
FGW37_RS29985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGW37_RS29990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGW37_RS29990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGW37_RS29995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGW37_RS29995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGW37_RS30090	COG1834	amidinotransferase
FGW37_RS30115	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FGW37_RS30140	COG1113	amino acid transport
FGW37_RS30160	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGW37_RS30165	COG1006	Multisubunit Na H antiporter MnhC subunit
FGW37_RS30195	COG0028	Belongs to the TPP enzyme family
FGW37_RS30205	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FGW37_RS30210	COG4948	Mandelate Racemase Muconate Lactonizing
FGW37_RS30215	COG0300	oxidoreductase activity
FGW37_RS30220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGW37_RS30225	COG0693	protein deglycase activity
FGW37_RS30230	COG1573	uracil-dna glycosylase
FGW37_RS30245	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FGW37_RS30245	COG1672	PFAM Archaeal ATPase
FGW37_RS30250	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGW37_RS30255	COG0477	Major facilitator Superfamily
FGW37_RS30260	COG0640	Transcriptional regulator
FGW37_RS30270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGW37_RS30275	COG2080	2 iron, 2 sulfur cluster binding
FGW37_RS30285	COG2226	methyltransferase
FGW37_RS30315	COG2814	Major facilitator Superfamily
FGW37_RS30325	COG2264	protein methyltransferase activity
FGW37_RS30330	COG0655	NAD(P)H dehydrogenase (quinone) activity
FGW37_RS30335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGW37_RS30335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGW37_RS30340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FGW37_RS30355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGW37_RS30410	COG2205	protein histidine kinase activity
FGW37_RS30415	COG1733	regulation of RNA biosynthetic process
FGW37_RS30420	COG0675	Transposase, IS605 OrfB family
FGW37_RS30440	COG0477	Major facilitator Superfamily
FGW37_RS30480	COG3260	NADH ubiquinone oxidoreductase 20
FGW37_RS30490	COG0650	Formate hydrogenlyase subunit 4
FGW37_RS30500	COG0651	ATP synthesis coupled electron transport
FGW37_RS30505	COG3261	NADH dehydrogenase
FGW37_RS30505	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FGW37_RS30550	COG1132	(ABC) transporter
FGW37_RS30555	COG0823	Involved in the tonB-independent uptake of proteins
FGW37_RS30565	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FGW37_RS30575	COG1064	alcohol dehydrogenase
FGW37_RS30590	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FGW37_RS30595	COG2197	response regulator
FGW37_RS30600	COG1476	TRANSCRIPTIONal
FGW37_RS30605	COG2226	methyltransferase
FGW37_RS30610	COG2072	flavoprotein involved in K transport
FGW37_RS30615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGW37_RS30645	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS30650	COG1960	acyl-CoA dehydrogenase activity
FGW37_RS30655	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS30685	COG2124	cytochrome p450
FGW37_RS30800	COG4977	sequence-specific DNA binding
FGW37_RS30810	COG2814	Major facilitator Superfamily
FGW37_RS30835	COG1982	Orn Lys Arg decarboxylase major
FGW37_RS30860	COG1940	carbohydrate kinase activity
FGW37_RS30890	COG0028	Belongs to the TPP enzyme family
FGW37_RS30935	COG2124	cytochrome p450
FGW37_RS30960	COG1132	(ABC) transporter
FGW37_RS31030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGW37_RS31040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FGW37_RS31055	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGW37_RS31060	COG1129	ABC transporter
FGW37_RS31095	COG1113	amino acid transport
FGW37_RS31120	COG1716	ATPase activity
FGW37_RS31120	COG1131	(ABC) transporter
FGW37_RS31120	COG0842	Transport permease protein
FGW37_RS31130	COG0515	serine threonine protein kinase
FGW37_RS31130	COG2815	serine threonine protein kinase
FGW37_RS31150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGW37_RS31150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGW37_RS31155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGW37_RS31165	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FGW37_RS31180	COG2192	nodulation
FGW37_RS31220	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FGW37_RS31225	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGW37_RS31245	COG1309	transcriptional regulator
FGW37_RS31265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGW37_RS31275	COG2813	Specifically methylates the guanine in position
FGW37_RS31315	COG1793	dna ligase
FGW37_RS31335	COG1970	mechanosensitive ion channel activity
FGW37_RS31355	COG0156	8-amino-7-oxononanoate synthase activity
FGW37_RS31365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGW37_RS31415	COG1309	transcriptional regulator
FGW37_RS31425	COG4770	biotin carboxylase activity
FGW37_RS31445	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FGW37_RS31470	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FGW37_RS31480	COG1113	amino acid transport
FGW37_RS31515	COG1278	Cold shock
FGW37_RS31550	COG2197	response regulator
FGW37_RS31595	COG3153	acetyltransferase
FGW37_RS31605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGW37_RS31650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGW37_RS31670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGW37_RS31690	COG2264	protein methyltransferase activity
FGW37_RS31725	COG3485	protocatechuate 3,4-dioxygenase
FGW37_RS31730	COG2207	Transcriptional regulator
FGW37_RS31755	COG1136	(ABC) transporter
FGW37_RS31770	COG0668	transmembrane transport
FGW37_RS31795	COG0667	Aldo Keto reductase
FGW37_RS31800	COG0386	Belongs to the glutathione peroxidase family
FGW37_RS31850	COG2197	response regulator
FGW37_RS31855	COG4585	Histidine kinase
FGW37_RS31870	COG2313	pseudouridylate synthase activity
FGW37_RS31895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGW37_RS31940	COG2409	Drug exporters of the RND superfamily
FGW37_RS31950	COG2135	peptidase activity
FGW37_RS31960	COG3540	Alkaline phosphatase
FGW37_RS31995	COG1090	epimerase
FGW37_RS32015	COG0154	amidase activity
FGW37_RS32020	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FGW37_RS32025	COG1280	lysine exporter protein (LysE YggA)
FGW37_RS32070	COG2124	cytochrome p450
FGW37_RS32070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FGW37_RS32090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGW37_RS32100	COG1793	dna ligase
FGW37_RS32100	COG3285	dna ligase
FGW37_RS32110	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FGW37_RS32130	COG0318	PFAM AMP-dependent synthetase and ligase
FGW37_RS32135	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FGW37_RS32150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGW37_RS32155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FGW37_RS32160	COG2080	2 iron, 2 sulfur cluster binding
FGW37_RS32185	COG3903	Transcriptional regulator
FGW37_RS32185	COG3629	intracellular signal transduction
FGW37_RS32200	COG1511	domain protein
FGW37_RS32215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGW37_RS32320	COG1247	-acetyltransferase
FGW37_RS32355	COG2329	Antibiotic biosynthesis monooxygenase
FGW37_RS32400	COG0513	Belongs to the DEAD box helicase family
FGW37_RS32410	COG4122	O-methyltransferase activity
FGW37_RS32415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGW37_RS32510	COG0488	(ABC) transporter
FGW37_RS32515	COG3209	COG3209 Rhs family protein
FGW37_RS32515	COG4104	PAAR repeat-containing protein
FGW37_RS32535	COG1012	belongs to the aldehyde dehydrogenase family
FGW37_RS32555	COG0242	peptide deformylase activity
FGW37_RS32580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGW37_RS32590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGW37_RS32635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGW37_RS32635	COG3321	synthase
FGW37_RS32690	COG0604	alcohol dehydrogenase
FGW37_RS32700	COG2124	cytochrome p450
FGW37_RS32750	COG0739	heme binding