locus-tag	class	description
CTZ40_RS00070	COG1309	transcriptional regulator
CTZ40_RS00170	COG2124	cytochrome p450
CTZ40_RS00225	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
CTZ40_RS00240	COG0596	Alpha beta hydrolase
CTZ40_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS00260	COG0583	DNA-binding transcription factor activity
CTZ40_RS00285	COG2814	Major facilitator Superfamily
CTZ40_RS00295	COG1051	belongs to the nudix hydrolase family
CTZ40_RS00335	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS00340	COG1309	transcriptional regulator
CTZ40_RS00355	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ40_RS00440	COG2409	Drug exporters of the RND superfamily
CTZ40_RS00445	COG0367	asparagine synthase
CTZ40_RS00460	COG2124	cytochrome p450
CTZ40_RS00505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CTZ40_RS00525	COG3437	response regulator, receiver
CTZ40_RS00525	COG4999	Histidine kinase
CTZ40_RS00525	COG2205	protein histidine kinase activity
CTZ40_RS00525	COG3850	Histidine kinase
CTZ40_RS00540	COG2226	methyltransferase
CTZ40_RS00565	COG0018	arginyl-trna synthetase
CTZ40_RS00600	COG0488	(ABC) transporter
CTZ40_RS00605	COG0488	(ABC) transporter
CTZ40_RS00615	COG1309	transcriptional regulator
CTZ40_RS00640	COG1175	transmembrane transport
CTZ40_RS00645	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS00650	COG0366	Alpha amylase catalytic
CTZ40_RS00685	COG2910	NAD(P)H-binding
CTZ40_RS00720	COG1396	sequence-specific DNA binding
CTZ40_RS00730	COG1309	transcriptional regulator
CTZ40_RS00775	COG0778	Nitroreductase
CTZ40_RS00785	COG2755	lipolytic protein G-D-S-L family
CTZ40_RS00785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CTZ40_RS00835	COG0181	hydroxymethylbilane synthase activity
CTZ40_RS00860	COG1131	(ABC) transporter
CTZ40_RS00875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ40_RS00890	COG1278	Cold shock
CTZ40_RS00910	COG2197	response regulator
CTZ40_RS00915	COG0142	geranyltranstransferase activity
CTZ40_RS00965	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CTZ40_RS00975	COG3012	SEC-C Motif Domain Protein
CTZ40_RS01010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS01015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS01020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS01025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS01030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS01035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS01065	COG2208	phosphoserine phosphatase activity
CTZ40_RS01065	COG1366	Belongs to the anti-sigma-factor antagonist family
CTZ40_RS01065	COG2172	sigma factor antagonist activity
CTZ40_RS01165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ40_RS01170	COG0463	Glycosyl transferase, family 2
CTZ40_RS01210	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS01230	COG1309	transcriptional regulator
CTZ40_RS01260	COG1797	cobyrinic acid a,c-diamide synthase activity
CTZ40_RS01275	COG0148	phosphopyruvate hydratase activity
CTZ40_RS01290	COG1309	transcriptional regulator
CTZ40_RS01315	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS01350	COG4221	oxidoreductase activity
CTZ40_RS01360	COG1278	Cold shock
CTZ40_RS01425	COG3321	synthase
CTZ40_RS01425	COG0604	alcohol dehydrogenase
CTZ40_RS01465	COG0531	amino acid
CTZ40_RS01470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ40_RS01475	COG2326	polyphosphate kinase activity
CTZ40_RS01505	COG0516	GMP reductase activity
CTZ40_RS01505	COG0517	IMP dehydrogenase activity
CTZ40_RS01540	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CTZ40_RS01545	COG0298	carbon dioxide binding
CTZ40_RS01550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ40_RS01560	COG0589	response to stress
CTZ40_RS01575	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ40_RS01580	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CTZ40_RS01585	COG2326	polyphosphate kinase activity
CTZ40_RS01630	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS01635	COG2070	2-Nitropropane dioxygenase
CTZ40_RS01665	COG0142	geranyltranstransferase activity
CTZ40_RS01715	COG0604	alcohol dehydrogenase
CTZ40_RS01725	COG3321	synthase
CTZ40_RS01725	COG0604	alcohol dehydrogenase
CTZ40_RS01740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTZ40_RS01755	COG2365	Tyrosine phosphatase family
CTZ40_RS01760	COG3321	synthase
CTZ40_RS01760	COG0604	alcohol dehydrogenase
CTZ40_RS01765	COG3321	synthase
CTZ40_RS01765	COG0604	alcohol dehydrogenase
CTZ40_RS01770	COG0604	alcohol dehydrogenase
CTZ40_RS01770	COG3321	synthase
CTZ40_RS01820	COG3979	chitinase
CTZ40_RS01830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ40_RS01835	COG1595	DNA-templated transcription, initiation
CTZ40_RS01865	COG2124	cytochrome p450
CTZ40_RS01865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CTZ40_RS01870	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CTZ40_RS01875	COG2382	esterase
CTZ40_RS01880	COG1819	glycosyl
CTZ40_RS01910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS01915	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS01925	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTZ40_RS01945	COG2382	esterase
CTZ40_RS01950	COG2814	Major facilitator Superfamily
CTZ40_RS01965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS01970	COG3433	isochorismatase activity
CTZ40_RS01970	COG1535	isochorismatase
CTZ40_RS01975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTZ40_RS01980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS01985	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS01990	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CTZ40_RS02000	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS02095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ40_RS02115	COG2207	Transcriptional regulator
CTZ40_RS02120	COG0604	alcohol dehydrogenase
CTZ40_RS02130	COG0667	Aldo Keto reductase
CTZ40_RS02150	COG0640	Transcriptional regulator
CTZ40_RS02155	COG0798	PFAM Bile acid sodium symporter
CTZ40_RS02160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTZ40_RS02175	COG0583	DNA-binding transcription factor activity
CTZ40_RS02185	COG1132	(ABC) transporter
CTZ40_RS02235	COG1595	DNA-templated transcription, initiation
CTZ40_RS02260	COG0277	FAD linked oxidase domain protein
CTZ40_RS02260	COG0247	lactate metabolic process
CTZ40_RS02265	COG3387	PFAM Glycoside hydrolase 15-related
CTZ40_RS02295	COG1140	nitrate reductase beta subunit
CTZ40_RS02320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTZ40_RS02335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CTZ40_RS02340	COG2079	MmgE PrpD family protein
CTZ40_RS02345	COG1396	sequence-specific DNA binding
CTZ40_RS02345	COG3800	Transcriptional regulator
CTZ40_RS02350	COG2080	2 iron, 2 sulfur cluster binding
CTZ40_RS02355	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CTZ40_RS02360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTZ40_RS02370	COG3629	intracellular signal transduction
CTZ40_RS02390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTZ40_RS02400	COG0367	asparagine synthase
CTZ40_RS02440	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS02445	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CTZ40_RS02485	COG2197	response regulator
CTZ40_RS02515	COG2124	cytochrome p450
CTZ40_RS02520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTZ40_RS02530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ40_RS02580	COG0116	Belongs to the methyltransferase superfamily
CTZ40_RS02580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CTZ40_RS02625	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ40_RS02655	COG1366	Belongs to the anti-sigma-factor antagonist family
CTZ40_RS02850	COG3547	Transposase (IS116 IS110 IS902 family)
CTZ40_RS02875	COG0739	heme binding
CTZ40_RS02925	COG0494	nUDIX hydrolase
CTZ40_RS03005	COG1309	transcriptional regulator
CTZ40_RS03070	COG3293	Transposase
CTZ40_RS03110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ40_RS03125	COG3321	synthase
CTZ40_RS03125	COG0604	alcohol dehydrogenase
CTZ40_RS03125	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS03145	COG1181	Belongs to the D-alanine--D-alanine ligase family
CTZ40_RS03215	COG3883	PFAM NLP P60 protein
CTZ40_RS03215	COG0791	NLP P60 protein
CTZ40_RS03410	COG1309	transcriptional regulator
CTZ40_RS03445	COG1140	nitrate reductase beta subunit
CTZ40_RS03450	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CTZ40_RS03570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ40_RS03590	COG2226	methyltransferase
CTZ40_RS03610	COG3021	interspecies interaction between organisms
CTZ40_RS03645	COG2755	lipolytic protein G-D-S-L family
CTZ40_RS03680	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTZ40_RS03705	COG1215	transferase activity, transferring glycosyl groups
CTZ40_RS03710	COG0515	serine threonine protein kinase
CTZ40_RS03735	COG1454	alcohol dehydrogenase
CTZ40_RS03740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ40_RS03790	COG4221	oxidoreductase activity
CTZ40_RS03820	COG1129	ABC transporter
CTZ40_RS03820	COG0842	Transport permease protein
CTZ40_RS03825	COG3321	synthase
CTZ40_RS03825	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS03825	COG0604	alcohol dehydrogenase
CTZ40_RS03835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ40_RS03850	COG1309	transcriptional regulator
CTZ40_RS03860	COG0640	Transcriptional regulator
CTZ40_RS03875	COG2124	cytochrome p450
CTZ40_RS03890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ40_RS03900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CTZ40_RS03925	COG0697	spore germination
CTZ40_RS03940	COG0640	Transcriptional regulator
CTZ40_RS03945	COG2814	Major facilitator Superfamily
CTZ40_RS03965	COG3655	Transcriptional regulator
CTZ40_RS03985	COG0534	Mate efflux family protein
CTZ40_RS04000	COG0516	GMP reductase activity
CTZ40_RS04000	COG0517	IMP dehydrogenase activity
CTZ40_RS04005	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS04015	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CTZ40_RS04025	COG0477	Major facilitator Superfamily
CTZ40_RS04030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTZ40_RS04040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTZ40_RS04050	COG2124	cytochrome p450
CTZ40_RS04060	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTZ40_RS04070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ40_RS04070	COG3320	Male sterility
CTZ40_RS04080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ40_RS04085	COG3629	intracellular signal transduction
CTZ40_RS04100	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CTZ40_RS04105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ40_RS04145	COG1902	pentaerythritol trinitrate reductase activity
CTZ40_RS04165	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CTZ40_RS04175	COG2971	BadF BadG BcrA BcrD
CTZ40_RS04185	COG2706	6-phosphogluconolactonase activity
CTZ40_RS04200	COG2391	methyltransferase activity
CTZ40_RS04210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ40_RS04215	COG4257	antibiotic catabolic process
CTZ40_RS04225	COG1595	DNA-templated transcription, initiation
CTZ40_RS04240	COG1793	dna ligase
CTZ40_RS04250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS04255	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS04255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS04255	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS04255	COG3321	synthase
CTZ40_RS04255	COG0300	oxidoreductase activity
CTZ40_RS04270	COG2175	clavaminate synthase activity
CTZ40_RS04305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ40_RS04305	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CTZ40_RS04330	COG0432	Pfam Uncharacterised protein family UPF0047
CTZ40_RS04335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ40_RS04340	COG1116	anion transmembrane transporter activity
CTZ40_RS04355	COG0492	ferredoxin-NADP+ reductase activity
CTZ40_RS04385	COG0477	Major facilitator Superfamily
CTZ40_RS04390	COG0247	lactate metabolic process
CTZ40_RS04395	COG1139	Iron-sulfur cluster binding protein
CTZ40_RS04400	COG1556	Lactate utilization protein
CTZ40_RS04430	COG1132	(ABC) transporter
CTZ40_RS04460	COG1132	(ABC) transporter
CTZ40_RS04465	COG1132	(ABC) transporter
CTZ40_RS04480	COG1946	Acyl-CoA thioesterase
CTZ40_RS04485	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS04490	COG3962	Belongs to the TPP enzyme family
CTZ40_RS04500	COG0156	8-amino-7-oxononanoate synthase activity
CTZ40_RS04505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ40_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS04535	COG2018	Roadblock/LC7 domain
CTZ40_RS04555	COG4122	O-methyltransferase activity
CTZ40_RS04590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CTZ40_RS04615	COG2353	YceI-like domain
CTZ40_RS04620	COG2040	homocysteine
CTZ40_RS04625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ40_RS04630	COG0765	amino acid transport
CTZ40_RS04635	COG1126	abc transporter atp-binding protein
CTZ40_RS04640	COG3458	cephalosporin-C deacetylase activity
CTZ40_RS04650	COG1070	Carbohydrate kinase
CTZ40_RS04660	COG1846	Transcriptional regulator
CTZ40_RS04660	COG1940	carbohydrate kinase activity
CTZ40_RS04665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ40_RS04670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ40_RS04670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ40_RS04680	COG2267	carboxylic ester hydrolase activity
CTZ40_RS04710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ40_RS04715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ40_RS04730	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CTZ40_RS04730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CTZ40_RS04740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ40_RS04750	COG1070	Carbohydrate kinase
CTZ40_RS04760	COG2814	Major facilitator Superfamily
CTZ40_RS04765	COG1349	DNA-binding transcription factor activity
CTZ40_RS04770	COG2986	histidine ammonia-lyase
CTZ40_RS04780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTZ40_RS04815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ40_RS04820	COG0601	transmembrane transport
CTZ40_RS04855	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS04860	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS04865	COG0604	alcohol dehydrogenase
CTZ40_RS04865	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS04865	COG3321	synthase
CTZ40_RS04895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ40_RS04900	COG2226	methyltransferase
CTZ40_RS04935	COG3572	ergothioneine biosynthetic process
CTZ40_RS04940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTZ40_RS04980	COG0823	Involved in the tonB-independent uptake of proteins
CTZ40_RS04985	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CTZ40_RS04985	COG5479	isomerase activity
CTZ40_RS05005	COG3959	Transketolase, thiamine diphosphate binding domain
CTZ40_RS05010	COG1252	NADH dehydrogenase
CTZ40_RS05015	COG1063	alcohol dehydrogenase
CTZ40_RS05105	COG1137	ATPase activity
CTZ40_RS05115	COG3360	Dodecin
CTZ40_RS05120	COG0531	amino acid
CTZ40_RS05140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ40_RS05155	COG2319	Wd-40 repeat
CTZ40_RS05155	COG4249	Peptidase C14 caspase catalytic subunit p20
CTZ40_RS05160	COG0180	Tryptophanyl-tRNA synthetase
CTZ40_RS05190	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS05195	COG0149	triose-phosphate isomerase activity
CTZ40_RS05200	COG0698	ribose 5-phosphate isomerase
CTZ40_RS05205	COG1063	alcohol dehydrogenase
CTZ40_RS05220	COG0583	DNA-binding transcription factor activity
CTZ40_RS05225	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS05240	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CTZ40_RS05260	COG1652	LysM domain
CTZ40_RS05290	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CTZ40_RS05295	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS05300	COG1024	Enoyl-CoA hydratase
CTZ40_RS05310	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CTZ40_RS05325	COG4762	Protein conserved in bacteria
CTZ40_RS05340	COG0789	Transcriptional regulator
CTZ40_RS05365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ40_RS05380	COG1940	carbohydrate kinase activity
CTZ40_RS05390	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CTZ40_RS05400	COG0583	DNA-binding transcription factor activity
CTZ40_RS05415	COG0174	glutamine synthetase
CTZ40_RS05430	COG3246	L-lysine catabolic process to acetate
CTZ40_RS05435	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ40_RS05440	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ40_RS05440	COG0824	Thioesterase
CTZ40_RS05470	COG1686	Belongs to the peptidase S11 family
CTZ40_RS05500	COG0789	Transcriptional regulator
CTZ40_RS05505	COG3959	Transketolase, thiamine diphosphate binding domain
CTZ40_RS05510	COG3958	Transketolase
CTZ40_RS05515	COG2267	carboxylic ester hydrolase activity
CTZ40_RS05520	COG0402	S-adenosylhomocysteine deaminase activity
CTZ40_RS05530	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS05550	COG2018	Roadblock/LC7 domain
CTZ40_RS05585	COG0367	asparagine synthase
CTZ40_RS05595	COG2814	Major facilitator Superfamily
CTZ40_RS05650	COG2755	lipolytic protein G-D-S-L family
CTZ40_RS05655	COG2365	Tyrosine phosphatase family
CTZ40_RS05670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CTZ40_RS05675	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CTZ40_RS05690	COG1657	PFAM Prenyltransferase squalene oxidase
CTZ40_RS05700	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CTZ40_RS05710	COG1562	ergosterol biosynthetic process
CTZ40_RS05715	COG1134	teichoic acid transport
CTZ40_RS05760	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CTZ40_RS05780	COG1846	Transcriptional regulator
CTZ40_RS05785	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CTZ40_RS05795	COG1024	Enoyl-CoA hydratase
CTZ40_RS05815	COG4977	sequence-specific DNA binding
CTZ40_RS05830	COG2183	response to ionizing radiation
CTZ40_RS05855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ40_RS05865	COG2936	dipeptidyl-peptidase activity
CTZ40_RS05880	COG3568	Endonuclease Exonuclease Phosphatase
CTZ40_RS05885	COG2197	response regulator
CTZ40_RS05900	COG0477	Major facilitator Superfamily
CTZ40_RS05905	COG1113	amino acid transport
CTZ40_RS05920	COG1024	Enoyl-CoA hydratase
CTZ40_RS05920	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ40_RS05925	COG0183	Belongs to the thiolase family
CTZ40_RS05930	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS05935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ40_RS05940	COG1285	pathogenesis
CTZ40_RS05955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ40_RS05960	COG3268	Saccharopine dehydrogenase
CTZ40_RS05965	COG1515	deoxyribonuclease V activity
CTZ40_RS05970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTZ40_RS05975	COG1309	transcriptional regulator
CTZ40_RS06005	COG2814	Major facilitator Superfamily
CTZ40_RS06010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ40_RS06020	COG1349	DNA-binding transcription factor activity
CTZ40_RS06070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ40_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS06095	COG1024	Enoyl-CoA hydratase
CTZ40_RS06095	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ40_RS06120	COG1309	transcriptional regulator
CTZ40_RS06125	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS06130	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS06135	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS06140	COG1289	transmembrane transporter activity
CTZ40_RS06145	COG1846	Transcriptional regulator
CTZ40_RS06150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ40_RS06180	COG0667	Aldo Keto reductase
CTZ40_RS06190	COG3226	Transcriptional regulator
CTZ40_RS06215	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS06220	COG2205	protein histidine kinase activity
CTZ40_RS06250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTZ40_RS06260	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CTZ40_RS06305	COG0583	DNA-binding transcription factor activity
CTZ40_RS06355	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS06360	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS06375	COG1376	ErfK ybiS ycfS ynhG family protein
CTZ40_RS06395	COG2124	cytochrome p450
CTZ40_RS06430	COG0204	Acyl-transferase
CTZ40_RS06440	COG3511	phospholipase C
CTZ40_RS06470	COG0287	Prephenate dehydrogenase
CTZ40_RS06495	COG2124	cytochrome p450
CTZ40_RS06500	COG2124	cytochrome p450
CTZ40_RS06510	COG0475	glutathione-regulated potassium exporter activity
CTZ40_RS06520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS06540	COG1132	(ABC) transporter
CTZ40_RS06555	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CTZ40_RS06575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ40_RS06585	COG2223	nitrite transmembrane transporter activity
CTZ40_RS06595	COG1605	Chorismate mutase
CTZ40_RS06595	COG0287	Prephenate dehydrogenase
CTZ40_RS06635	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS06650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CTZ40_RS06660	COG1063	alcohol dehydrogenase
CTZ40_RS06695	COG0583	DNA-binding transcription factor activity
CTZ40_RS06705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ40_RS06720	COG0656	L-ascorbic acid biosynthetic process
CTZ40_RS06735	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS06740	COG4106	trans-aconitate 2-methyltransferase activity
CTZ40_RS06760	COG1595	DNA-templated transcription, initiation
CTZ40_RS06765	COG1295	ribonuclease BN
CTZ40_RS06770	COG2154	pterin-4-alpha-carbinolamine dehydratase
CTZ40_RS06775	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CTZ40_RS06780	COG4941	Belongs to the sigma-70 factor family
CTZ40_RS06810	COG0789	Transcriptional regulator
CTZ40_RS06815	COG1309	transcriptional regulator
CTZ40_RS06820	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS06825	COG0531	amino acid
CTZ40_RS06835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ40_RS06845	COG0431	NADPH-dependent FMN reductase
CTZ40_RS06860	COG0583	DNA-binding transcription factor activity
CTZ40_RS06865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CTZ40_RS06895	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS06905	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ40_RS06915	COG0517	IMP dehydrogenase activity
CTZ40_RS06920	COG0671	phosphoesterase, PA-phosphatase related
CTZ40_RS06925	COG2226	methyltransferase
CTZ40_RS06950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ40_RS06980	COG0010	Belongs to the arginase family
CTZ40_RS07000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ40_RS07020	COG2124	cytochrome p450
CTZ40_RS07035	COG1619	proteins homologs of microcin C7 resistance protein MccF
CTZ40_RS07045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTZ40_RS07050	COG2362	D-Aminopeptidase
CTZ40_RS07065	COG2208	phosphoserine phosphatase activity
CTZ40_RS07065	COG2172	sigma factor antagonist activity
CTZ40_RS07065	COG1366	Belongs to the anti-sigma-factor antagonist family
CTZ40_RS07070	COG2207	Transcriptional regulator
CTZ40_RS07105	COG0456	acetyltransferase
CTZ40_RS07115	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ40_RS07130	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CTZ40_RS07130	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CTZ40_RS07135	COG2301	Belongs to the HpcH HpaI aldolase family
CTZ40_RS07145	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS07150	COG0688	phosphatidylethanolamine metabolic process
CTZ40_RS07160	COG1929	Belongs to the glycerate kinase type-1 family
CTZ40_RS07165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ40_RS07180	COG2304	oxidoreductase activity
CTZ40_RS07200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ40_RS07215	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CTZ40_RS07240	COG0640	Transcriptional regulator
CTZ40_RS07250	COG0483	inositol monophosphate 1-phosphatase activity
CTZ40_RS07260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTZ40_RS07275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ40_RS07285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CTZ40_RS07305	COG1064	alcohol dehydrogenase
CTZ40_RS07310	COG1278	Cold shock
CTZ40_RS07315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ40_RS07330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ40_RS07330	COG0723	plastoquinol--plastocyanin reductase activity
CTZ40_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS07355	COG0477	Major facilitator Superfamily
CTZ40_RS07360	COG1335	isochorismatase
CTZ40_RS07380	COG0405	Gamma-glutamyltransferase
CTZ40_RS07415	COG1959	2 iron, 2 sulfur cluster binding
CTZ40_RS07420	COG1017	nitric oxide dioxygenase activity
CTZ40_RS07420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ40_RS07430	COG0765	amino acid transport
CTZ40_RS07435	COG0765	amino acid transport
CTZ40_RS07440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ40_RS07445	COG1126	abc transporter atp-binding protein
CTZ40_RS07475	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ40_RS07485	COG0483	inositol monophosphate 1-phosphatase activity
CTZ40_RS07490	COG0583	DNA-binding transcription factor activity
CTZ40_RS07495	COG0542	response to heat
CTZ40_RS07505	COG3693	PFAM glycoside hydrolase, family 10
CTZ40_RS07530	COG2814	Major facilitator Superfamily
CTZ40_RS07565	COG0251	oxidation-reduction process
CTZ40_RS07570	COG0583	DNA-binding transcription factor activity
CTZ40_RS07585	COG1940	carbohydrate kinase activity
CTZ40_RS07610	COG2188	Transcriptional regulator
CTZ40_RS07615	COG0789	Transcriptional regulator
CTZ40_RS07620	COG1902	pentaerythritol trinitrate reductase activity
CTZ40_RS07635	COG0800	Aldolase
CTZ40_RS07675	COG0237	dephospho-CoA kinase activity
CTZ40_RS07675	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CTZ40_RS07680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CTZ40_RS07685	COG1414	Transcriptional regulator
CTZ40_RS07700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTZ40_RS07710	COG1288	antiporter activity
CTZ40_RS07735	COG2233	PERMEase
CTZ40_RS07745	COG2233	PERMEase
CTZ40_RS07755	COG2351	hydroxyisourate hydrolase activity
CTZ40_RS07775	COG3622	Belongs to the hyi family
CTZ40_RS07780	COG2084	Dehydrogenase
CTZ40_RS07790	COG0753	catalase activity
CTZ40_RS07800	COG1126	abc transporter atp-binding protein
CTZ40_RS07830	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS07835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ40_RS07840	COG2197	response regulator
CTZ40_RS07855	COG0583	DNA-binding transcription factor activity
CTZ40_RS07860	COG4552	Acetyltransferase involved in intracellular survival and related
CTZ40_RS07865	COG1285	pathogenesis
CTZ40_RS07880	COG1733	regulation of RNA biosynthetic process
CTZ40_RS07900	COG2252	PERMEase
CTZ40_RS07905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTZ40_RS07955	COG0028	Belongs to the TPP enzyme family
CTZ40_RS07975	COG1162	GTPase activity
CTZ40_RS08005	COG1204	response to ionizing radiation
CTZ40_RS08010	COG3629	intracellular signal transduction
CTZ40_RS08010	COG3903	Transcriptional regulator
CTZ40_RS08025	COG1309	transcriptional regulator
CTZ40_RS08060	COG0028	Belongs to the TPP enzyme family
CTZ40_RS08095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ40_RS08100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTZ40_RS08105	COG3485	protocatechuate 3,4-dioxygenase
CTZ40_RS08110	COG3485	protocatechuate 3,4-dioxygenase
CTZ40_RS08115	COG0183	Belongs to the thiolase family
CTZ40_RS08120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ40_RS08125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ40_RS08130	COG1414	Transcriptional regulator
CTZ40_RS08180	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS08205	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ40_RS08215	COG0175	sulfate reduction
CTZ40_RS08220	COG0529	Catalyzes the synthesis of activated sulfate
CTZ40_RS08245	COG1116	anion transmembrane transporter activity
CTZ40_RS08245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ40_RS08250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ40_RS08275	COG2936	dipeptidyl-peptidase activity
CTZ40_RS08305	COG0859	PFAM glycosyl transferase family 9
CTZ40_RS08315	COG1088	dTDP-glucose 4,6-dehydratase activity
CTZ40_RS08320	COG2192	nodulation
CTZ40_RS08330	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CTZ40_RS08345	COG0297	glycogen (starch) synthase activity
CTZ40_RS08350	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CTZ40_RS08355	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CTZ40_RS08355	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CTZ40_RS08365	COG1215	transferase activity, transferring glycosyl groups
CTZ40_RS08445	COG2362	D-Aminopeptidase
CTZ40_RS08450	COG0583	DNA-binding transcription factor activity
CTZ40_RS08455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ40_RS08485	COG0693	protein deglycase activity
CTZ40_RS08495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ40_RS08500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CTZ40_RS08505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ40_RS08510	COG2197	response regulator
CTZ40_RS08515	COG4585	Histidine kinase
CTZ40_RS08525	COG1136	(ABC) transporter
CTZ40_RS08555	COG4152	abc transporter atp-binding protein
CTZ40_RS08585	COG1280	lysine exporter protein (LysE YggA)
CTZ40_RS08590	COG3220	belongs to the UPF0276 family
CTZ40_RS08615	COG3253	May function as heme-dependent peroxidase
CTZ40_RS08620	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CTZ40_RS08630	COG0183	Belongs to the thiolase family
CTZ40_RS08645	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ40_RS08650	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CTZ40_RS08665	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CTZ40_RS08675	COG0183	Belongs to the thiolase family
CTZ40_RS08680	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ40_RS08680	COG1024	Enoyl-CoA hydratase
CTZ40_RS08695	COG0531	amino acid
CTZ40_RS08700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CTZ40_RS08710	COG4214	carbohydrate transport
CTZ40_RS08720	COG4213	ABC transporter substrate-binding protein
CTZ40_RS08735	COG1175	transmembrane transport
CTZ40_RS08740	COG1653	transport
CTZ40_RS08755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CTZ40_RS08760	COG4106	trans-aconitate 2-methyltransferase activity
CTZ40_RS08765	COG1120	ATPase activity
CTZ40_RS08770	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CTZ40_RS08785	COG0596	Alpha beta hydrolase
CTZ40_RS08800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CTZ40_RS08805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ40_RS08820	COG2223	nitrite transmembrane transporter activity
CTZ40_RS08835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ40_RS08845	COG1063	alcohol dehydrogenase
CTZ40_RS08870	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS08875	COG1024	Enoyl-CoA hydratase
CTZ40_RS08895	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS08910	COG0546	phosphoglycolate phosphatase activity
CTZ40_RS08935	COG1024	Enoyl-CoA hydratase
CTZ40_RS08940	COG0531	amino acid
CTZ40_RS08945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CTZ40_RS08950	COG2235	arginine
CTZ40_RS09015	COG2197	response regulator
CTZ40_RS09055	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTZ40_RS09070	COG2208	phosphoserine phosphatase activity
CTZ40_RS09070	COG2770	Histidine kinase
CTZ40_RS09110	COG1799	cell septum assembly
CTZ40_RS09115	COG0598	Magnesium transport protein CorA
CTZ40_RS09125	COG0302	gtp cyclohydrolase
CTZ40_RS09140	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTZ40_RS09160	COG4638	Rieske (2fe-2S)
CTZ40_RS09165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CTZ40_RS09180	COG2986	histidine ammonia-lyase
CTZ40_RS09185	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS09205	COG2814	Major facilitator Superfamily
CTZ40_RS09210	COG0583	DNA-binding transcription factor activity
CTZ40_RS09230	COG2201	protein-glutamate methylesterase activity
CTZ40_RS09255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ40_RS09260	COG0601	transmembrane transport
CTZ40_RS09265	COG0747	negative chemotaxis
CTZ40_RS09280	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ40_RS09285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ40_RS09295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CTZ40_RS09320	COG0583	DNA-binding transcription factor activity
CTZ40_RS09330	COG0702	epimerase
CTZ40_RS09350	COG1535	isochorismatase
CTZ40_RS09350	COG3433	isochorismatase activity
CTZ40_RS09355	COG1535	isochorismatase
CTZ40_RS09355	COG3433	isochorismatase activity
CTZ40_RS09360	COG1021	2,3-dihydroxybenzoate-AMP ligase
CTZ40_RS09365	COG1169	isochorismate synthase
CTZ40_RS09370	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS09375	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS09380	COG2382	esterase
CTZ40_RS09390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS09400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTZ40_RS09405	COG1120	ATPase activity
CTZ40_RS09420	COG2264	protein methyltransferase activity
CTZ40_RS09450	COG2124	cytochrome p450
CTZ40_RS09515	COG3842	ATPase activity
CTZ40_RS09530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CTZ40_RS09535	COG0066	3-isopropylmalate dehydratase activity
CTZ40_RS09555	COG2197	response regulator
CTZ40_RS09580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS09615	COG1834	amidinotransferase
CTZ40_RS09620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTZ40_RS09625	COG0134	indole-3-glycerol-phosphate synthase activity
CTZ40_RS09630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTZ40_RS09640	COG0512	Glutamine amidotransferase of anthranilate synthase
CTZ40_RS09640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTZ40_RS09650	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CTZ40_RS09670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS09675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS09690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CTZ40_RS09695	COG0531	amino acid
CTZ40_RS09725	COG0569	domain protein
CTZ40_RS09760	COG0577	efflux transmembrane transporter activity
CTZ40_RS09760	COG1136	(ABC) transporter
CTZ40_RS09770	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CTZ40_RS09775	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CTZ40_RS09780	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CTZ40_RS09795	COG0756	dUTP diphosphatase activity
CTZ40_RS09820	COG2205	protein histidine kinase activity
CTZ40_RS09825	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS09830	COG0483	inositol monophosphate 1-phosphatase activity
CTZ40_RS09835	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CTZ40_RS09870	COG1435	thymidine kinase activity
CTZ40_RS09890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTZ40_RS09895	COG1802	Transcriptional regulator
CTZ40_RS09910	COG0612	Peptidase, M16
CTZ40_RS09915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CTZ40_RS09925	COG0372	Belongs to the citrate synthase family
CTZ40_RS09930	COG0372	Belongs to the citrate synthase family
CTZ40_RS09950	COG3290	protein histidine kinase activity
CTZ40_RS09955	COG4565	transcriptional regulatory protein
CTZ40_RS09960	COG2197	response regulator
CTZ40_RS09965	COG4585	Histidine kinase
CTZ40_RS09975	COG0187	DNA topoisomerase II activity
CTZ40_RS09990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CTZ40_RS09995	COG2186	Transcriptional regulator
CTZ40_RS10020	COG0514	ATP-dependent DNA helicase (RecQ)
CTZ40_RS10035	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTZ40_RS10050	COG0488	(ABC) transporter
CTZ40_RS10065	COG0154	amidase activity
CTZ40_RS10070	COG3226	Transcriptional regulator
CTZ40_RS10085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTZ40_RS10090	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CTZ40_RS10095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ40_RS10135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTZ40_RS10145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ40_RS10150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CTZ40_RS10160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CTZ40_RS10180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CTZ40_RS10195	COG1278	Cold shock
CTZ40_RS10200	COG2205	protein histidine kinase activity
CTZ40_RS10210	COG1126	abc transporter atp-binding protein
CTZ40_RS10220	COG0765	amino acid transport
CTZ40_RS10225	COG0765	amino acid transport
CTZ40_RS10260	COG2409	Drug exporters of the RND superfamily
CTZ40_RS10265	COG0628	permease
CTZ40_RS10290	COG1917	Cupin 2, conserved barrel domain protein
CTZ40_RS10290	COG2207	Transcriptional regulator
CTZ40_RS10295	COG1201	RNA secondary structure unwinding
CTZ40_RS10300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CTZ40_RS10310	COG0181	hydroxymethylbilane synthase activity
CTZ40_RS10325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ40_RS10330	COG0783	Belongs to the Dps family
CTZ40_RS10335	COG1396	sequence-specific DNA binding
CTZ40_RS10340	COG1058	Belongs to the CinA family
CTZ40_RS10340	COG1546	Belongs to the CinA family
CTZ40_RS10350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CTZ40_RS10360	COG1674	ftsk spoiiie
CTZ40_RS10370	COG4999	Histidine kinase
CTZ40_RS10370	COG3850	Histidine kinase
CTZ40_RS10370	COG3437	response regulator, receiver
CTZ40_RS10370	COG2205	protein histidine kinase activity
CTZ40_RS10375	COG2208	phosphoserine phosphatase activity
CTZ40_RS10375	COG2770	Histidine kinase
CTZ40_RS10410	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CTZ40_RS10415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ40_RS10420	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CTZ40_RS10440	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CTZ40_RS10445	COG0612	Peptidase, M16
CTZ40_RS10450	COG1185	polyribonucleotide nucleotidyltransferase activity
CTZ40_RS10455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CTZ40_RS10465	COG1674	ftsk spoiiie
CTZ40_RS10590	COG0455	bacterial-type flagellum organization
CTZ40_RS10600	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTZ40_RS10605	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CTZ40_RS10615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CTZ40_RS10630	COG0779	Required for maturation of 30S ribosomal subunits
CTZ40_RS10645	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
CTZ40_RS10650	COG0442	prolyl-tRNA aminoacylation
CTZ40_RS10665	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CTZ40_RS10670	COG0750	zinc metalloprotease
CTZ40_RS10675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CTZ40_RS10690	COG2197	response regulator
CTZ40_RS10695	COG4585	Histidine kinase
CTZ40_RS10700	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS10785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ40_RS10790	COG1177	transmembrane transport
CTZ40_RS10795	COG1176	ABC-type spermidine putrescine transport system, permease component I
CTZ40_RS10800	COG3842	ATPase activity
CTZ40_RS10810	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS10825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ40_RS10850	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS10860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CTZ40_RS10885	COG3842	ATPase activity
CTZ40_RS10890	COG4208	sulfate ABC transporter
CTZ40_RS10900	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CTZ40_RS10910	COG0233	cytoplasmic translational termination
CTZ40_RS10915	COG0528	UMP kinase activity
CTZ40_RS10920	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CTZ40_RS10925	COG0052	Belongs to the universal ribosomal protein uS2 family
CTZ40_RS10940	COG1191	sigma factor activity
CTZ40_RS10955	COG0792	nuclease activity
CTZ40_RS10975	COG0681	Belongs to the peptidase S26 family
CTZ40_RS10985	COG0681	Belongs to the peptidase S26 family
CTZ40_RS10995	COG0335	large ribosomal subunit rRNA binding
CTZ40_RS11000	COG0336	Belongs to the RNA methyltransferase TrmD family
CTZ40_RS11005	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTZ40_RS11010	COG1837	Belongs to the UPF0109 family
CTZ40_RS11015	COG0228	four-way junction DNA binding
CTZ40_RS11055	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CTZ40_RS11060	COG0626	cystathionine gamma-synthase activity
CTZ40_RS11070	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CTZ40_RS11080	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CTZ40_RS11115	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ40_RS11125	COG0477	Major facilitator Superfamily
CTZ40_RS11130	COG1196	nuclear chromosome segregation
CTZ40_RS11140	COG1254	Belongs to the acylphosphatase family
CTZ40_RS11160	COG1733	regulation of RNA biosynthetic process
CTZ40_RS11165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CTZ40_RS11170	COG0571	ribonuclease III activity
CTZ40_RS11175	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CTZ40_RS11190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CTZ40_RS11195	COG0742	ribosomal rna small subunit methyltransferase
CTZ40_RS11205	COG1461	Dihydroxyacetone kinase
CTZ40_RS11210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CTZ40_RS11215	COG0351	phosphomethylpyrimidine kinase
CTZ40_RS11235	COG1181	Belongs to the D-alanine--D-alanine ligase family
CTZ40_RS11240	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CTZ40_RS11250	COG1920	GTP binding
CTZ40_RS11260	COG0776	regulation of translation
CTZ40_RS11270	COG0066	3-isopropylmalate dehydratase activity
CTZ40_RS11275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CTZ40_RS11280	COG1414	Transcriptional regulator
CTZ40_RS11370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ40_RS11375	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTZ40_RS11390	COG2018	Roadblock/LC7 domain
CTZ40_RS11410	COG2018	Roadblock/LC7 domain
CTZ40_RS11425	COG2376	Dihydroxyacetone kinase
CTZ40_RS11430	COG2814	Major facilitator Superfamily
CTZ40_RS11445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ40_RS11450	COG5492	domain, Protein
CTZ40_RS11455	COG2353	YceI-like domain
CTZ40_RS11460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTZ40_RS11465	COG0477	Major facilitator Superfamily
CTZ40_RS11475	COG1309	transcriptional regulator
CTZ40_RS11480	COG2957	Belongs to the agmatine deiminase family
CTZ40_RS11485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CTZ40_RS11490	COG0473	3-isopropylmalate dehydrogenase activity
CTZ40_RS11505	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS11510	COG0506	proline dehydrogenase activity
CTZ40_RS11515	COG3835	regulator
CTZ40_RS11535	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CTZ40_RS11540	COG0440	acetolactate synthase activity
CTZ40_RS11560	COG0667	Aldo Keto reductase
CTZ40_RS11565	COG2133	pyrroloquinoline quinone binding
CTZ40_RS11575	COG2197	response regulator
CTZ40_RS11590	COG2409	Drug exporters of the RND superfamily
CTZ40_RS11595	COG3511	phospholipase C
CTZ40_RS11640	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ40_RS11650	COG0154	amidase activity
CTZ40_RS11655	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ40_RS11665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CTZ40_RS11675	COG4221	oxidoreductase activity
CTZ40_RS11685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ40_RS11700	COG0667	Aldo Keto reductase
CTZ40_RS11705	COG0482	sulfurtransferase activity
CTZ40_RS11730	COG3629	intracellular signal transduction
CTZ40_RS11730	COG3903	Transcriptional regulator
CTZ40_RS11755	COG2860	membrane
CTZ40_RS11775	COG4608	Belongs to the ABC transporter superfamily
CTZ40_RS11780	COG0444	Belongs to the ABC transporter superfamily
CTZ40_RS11785	COG0601	transmembrane transport
CTZ40_RS11790	COG0747	negative chemotaxis
CTZ40_RS11795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ40_RS11820	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CTZ40_RS11825	COG0509	glycine decarboxylation via glycine cleavage system
CTZ40_RS11830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CTZ40_RS11835	COG0531	amino acid
CTZ40_RS11840	COG1760	l-serine dehydratase
CTZ40_RS11880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTZ40_RS11895	COG0785	Cytochrome C biogenesis protein
CTZ40_RS11900	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CTZ40_RS11900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ40_RS11925	COG1376	ErfK ybiS ycfS ynhG family protein
CTZ40_RS11935	COG1132	(ABC) transporter
CTZ40_RS11940	COG1132	(ABC) transporter
CTZ40_RS11945	COG0477	Major facilitator Superfamily
CTZ40_RS11950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ40_RS11955	COG2272	Belongs to the type-B carboxylesterase lipase family
CTZ40_RS11960	COG1252	NADH dehydrogenase
CTZ40_RS11965	COG1595	DNA-templated transcription, initiation
CTZ40_RS11970	COG2318	DinB family
CTZ40_RS11990	COG2197	response regulator
CTZ40_RS12015	COG0058	SHG alpha-glucan phosphorylase activity
CTZ40_RS12025	COG0366	Alpha amylase catalytic
CTZ40_RS12030	COG0366	Alpha amylase catalytic
CTZ40_RS12040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CTZ40_RS12045	COG0667	Aldo Keto reductase
CTZ40_RS12060	COG0477	Major facilitator Superfamily
CTZ40_RS12070	COG1301	dicarboxylic acid transport
CTZ40_RS12075	COG3290	protein histidine kinase activity
CTZ40_RS12080	COG4565	transcriptional regulatory protein
CTZ40_RS12090	COG1175	transmembrane transport
CTZ40_RS12095	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS12105	COG2319	Wd-40 repeat
CTZ40_RS12105	COG4249	Peptidase C14 caspase catalytic subunit p20
CTZ40_RS12115	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTZ40_RS12125	COG0577	efflux transmembrane transporter activity
CTZ40_RS12130	COG1295	ribonuclease BN
CTZ40_RS12135	COG0753	catalase activity
CTZ40_RS12160	COG0205	6-phosphofructokinase activity
CTZ40_RS12165	COG0857	belongs to the CobB CobQ family
CTZ40_RS12165	COG0280	phosphate acetyltransferase
CTZ40_RS12170	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTZ40_RS12230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTZ40_RS12235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CTZ40_RS12255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTZ40_RS12260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CTZ40_RS12260	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CTZ40_RS12315	COG2205	protein histidine kinase activity
CTZ40_RS12320	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS12340	COG0183	Belongs to the thiolase family
CTZ40_RS12360	COG1131	(ABC) transporter
CTZ40_RS12395	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CTZ40_RS12410	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ40_RS12440	COG3850	Histidine kinase
CTZ40_RS12445	COG2197	response regulator
CTZ40_RS12460	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CTZ40_RS12465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CTZ40_RS12470	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CTZ40_RS12475	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CTZ40_RS12480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CTZ40_RS12485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CTZ40_RS12490	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CTZ40_RS12510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CTZ40_RS12515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTZ40_RS12525	COG2890	protein-(glutamine-N5) methyltransferase activity
CTZ40_RS12530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CTZ40_RS12535	COG0254	rRNA binding
CTZ40_RS12550	COG0083	homoserine kinase activity
CTZ40_RS12555	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTZ40_RS12560	COG0460	homoserine dehydrogenase
CTZ40_RS12565	COG0019	diaminopimelate decarboxylase activity
CTZ40_RS12570	COG0018	arginyl-trna synthetase
CTZ40_RS12575	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS12600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS12630	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS12640	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ40_RS12680	COG2124	cytochrome p450
CTZ40_RS12690	COG0768	penicillin binding
CTZ40_RS12700	COG1119	ATPase activity
CTZ40_RS12770	COG1309	transcriptional regulator
CTZ40_RS12800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CTZ40_RS12815	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS12820	COG2205	protein histidine kinase activity
CTZ40_RS12825	COG0567	Dehydrogenase, E1 component
CTZ40_RS12825	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ40_RS12930	COG0604	alcohol dehydrogenase
CTZ40_RS12945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ40_RS12950	COG0765	amino acid transport
CTZ40_RS12955	COG1126	abc transporter atp-binding protein
CTZ40_RS12960	COG4106	trans-aconitate 2-methyltransferase activity
CTZ40_RS12980	COG2201	protein-glutamate methylesterase activity
CTZ40_RS13015	COG3629	intracellular signal transduction
CTZ40_RS13015	COG3903	Transcriptional regulator
CTZ40_RS13045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CTZ40_RS13050	COG1993	acr, cog1993
CTZ40_RS13055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CTZ40_RS13060	COG2186	Transcriptional regulator
CTZ40_RS13065	COG2807	transmembrane transport
CTZ40_RS13070	COG0598	Magnesium transport protein CorA
CTZ40_RS13085	COG0477	Major facilitator Superfamily
CTZ40_RS13100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTZ40_RS13115	COG2066	Belongs to the glutaminase family
CTZ40_RS13170	COG1597	lipid kinase activity
CTZ40_RS13185	COG1309	transcriptional regulator
CTZ40_RS13190	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS13195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ40_RS13200	COG0363	glucosamine-6-phosphate deaminase activity
CTZ40_RS13205	COG1472	Belongs to the glycosyl hydrolase 3 family
CTZ40_RS13210	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS13215	COG1175	transmembrane transport
CTZ40_RS13220	COG2182	Extracellular solute-binding protein
CTZ40_RS13225	COG2188	Transcriptional regulator
CTZ40_RS13230	COG1966	Carbon starvation protein
CTZ40_RS13270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTZ40_RS13275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ40_RS13280	COG0242	peptide deformylase activity
CTZ40_RS13290	COG5662	AntiSigma factor
CTZ40_RS13295	COG1595	DNA-templated transcription, initiation
CTZ40_RS13300	COG1396	sequence-specific DNA binding
CTZ40_RS13300	COG3800	Transcriptional regulator
CTZ40_RS13310	COG2135	peptidase activity
CTZ40_RS13320	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTZ40_RS13340	COG2076	Multidrug Resistance protein
CTZ40_RS13350	COG0483	inositol monophosphate 1-phosphatase activity
CTZ40_RS13360	COG0753	catalase activity
CTZ40_RS13390	COG1615	UPF0182 protein
CTZ40_RS13400	COG3480	Lon protease (S16) C-terminal proteolytic domain
CTZ40_RS13455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ40_RS13505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTZ40_RS13510	COG0210	DNA helicase
CTZ40_RS13555	COG4172	Belongs to the ABC transporter superfamily
CTZ40_RS13560	COG0601	transmembrane transport
CTZ40_RS13565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ40_RS13580	COG2267	carboxylic ester hydrolase activity
CTZ40_RS13620	COG1432	Conserved Protein
CTZ40_RS13625	COG2095	MarC family integral membrane protein
CTZ40_RS13640	COG2814	Major facilitator Superfamily
CTZ40_RS13650	COG0598	Magnesium transport protein CorA
CTZ40_RS13685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CTZ40_RS13690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ40_RS13700	COG1595	DNA-templated transcription, initiation
CTZ40_RS13715	COG1024	Enoyl-CoA hydratase
CTZ40_RS13720	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ40_RS13730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTZ40_RS13740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTZ40_RS13780	COG2197	response regulator
CTZ40_RS13785	COG4585	Histidine kinase
CTZ40_RS13795	COG1131	(ABC) transporter
CTZ40_RS13815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CTZ40_RS13835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ40_RS13840	COG4166	transmembrane transport
CTZ40_RS13850	COG0444	Belongs to the ABC transporter superfamily
CTZ40_RS13855	COG4608	Belongs to the ABC transporter superfamily
CTZ40_RS13865	COG4608	Belongs to the ABC transporter superfamily
CTZ40_RS13875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ40_RS13880	COG0601	transmembrane transport
CTZ40_RS13910	COG4608	Belongs to the ABC transporter superfamily
CTZ40_RS13915	COG0444	Belongs to the ABC transporter superfamily
CTZ40_RS13920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ40_RS13925	COG0601	transmembrane transport
CTZ40_RS13930	COG4166	transmembrane transport
CTZ40_RS13935	COG1217	gtp-binding protein TYPA
CTZ40_RS13955	COG1053	succinate dehydrogenase
CTZ40_RS13985	COG0531	amino acid
CTZ40_RS14000	COG0596	Alpha beta hydrolase
CTZ40_RS14000	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ40_RS14030	COG0012	GTP binding
CTZ40_RS14045	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CTZ40_RS14055	COG1570	exodeoxyribonuclease VII activity
CTZ40_RS14060	COG1722	exodeoxyribonuclease VII activity
CTZ40_RS14065	COG0778	Nitroreductase
CTZ40_RS14090	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ40_RS14090	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ40_RS14095	COG0114	fumarate hydratase activity
CTZ40_RS14120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CTZ40_RS14135	COG1136	(ABC) transporter
CTZ40_RS14150	COG1136	(ABC) transporter
CTZ40_RS14175	COG0450	alkyl hydroperoxide reductase
CTZ40_RS14180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ40_RS14200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CTZ40_RS14205	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTZ40_RS14210	COG0667	Aldo Keto reductase
CTZ40_RS14255	COG2885	chlorophyll binding
CTZ40_RS14355	COG2610	gluconate transmembrane transporter activity
CTZ40_RS14360	COG0251	oxidation-reduction process
CTZ40_RS14365	COG1414	Transcriptional regulator
CTZ40_RS14380	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CTZ40_RS14400	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CTZ40_RS14415	COG0789	Transcriptional regulator
CTZ40_RS14425	COG1331	Highly conserved protein containing a thioredoxin domain
CTZ40_RS14445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CTZ40_RS14455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ40_RS14470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTZ40_RS14475	COG2255	four-way junction helicase activity
CTZ40_RS14480	COG1595	DNA-templated transcription, initiation
CTZ40_RS14500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CTZ40_RS14555	COG2986	histidine ammonia-lyase
CTZ40_RS14565	COG1024	Enoyl-CoA hydratase
CTZ40_RS14570	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CTZ40_RS14580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ40_RS14595	COG0768	penicillin binding
CTZ40_RS14600	COG0424	maF-like protein
CTZ40_RS14640	COG4770	biotin carboxylase activity
CTZ40_RS14645	COG0702	epimerase
CTZ40_RS14680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ40_RS14715	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS14720	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS14735	COG1595	DNA-templated transcription, initiation
CTZ40_RS14740	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS14770	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ40_RS14785	COG0583	DNA-binding transcription factor activity
CTZ40_RS14790	COG2814	Major facilitator Superfamily
CTZ40_RS14820	COG1079	Belongs to the binding-protein-dependent transport system permease family
CTZ40_RS14825	COG4603	Belongs to the binding-protein-dependent transport system permease family
CTZ40_RS14830	COG3845	ABC transporter
CTZ40_RS14835	COG1744	ABC transporter substrate-binding protein PnrA-like
CTZ40_RS14840	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CTZ40_RS14840	COG1473	amidohydrolase
CTZ40_RS14850	COG2089	acid synthase
CTZ40_RS14855	COG1083	cytidylyl-transferase
CTZ40_RS14865	COG1216	Glycosyl transferase, family 2
CTZ40_RS14875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CTZ40_RS14910	COG3265	gluconokinase activity
CTZ40_RS14915	COG2186	Transcriptional regulator
CTZ40_RS14940	COG3961	Belongs to the TPP enzyme family
CTZ40_RS14945	COG1846	Transcriptional regulator
CTZ40_RS14970	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CTZ40_RS14980	COG2009	succinate dehydrogenase
CTZ40_RS14990	COG1053	succinate dehydrogenase
CTZ40_RS14995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTZ40_RS15025	COG1404	Belongs to the peptidase S8 family
CTZ40_RS15045	COG1295	ribonuclease BN
CTZ40_RS15055	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTZ40_RS15080	COG0180	Tryptophanyl-tRNA synthetase
CTZ40_RS15090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CTZ40_RS15095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ40_RS15100	COG0754	glutathionylspermidine amidase activity
CTZ40_RS15115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ40_RS15120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ40_RS15125	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ40_RS15150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ40_RS15155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ40_RS15165	COG1396	sequence-specific DNA binding
CTZ40_RS15180	COG2197	response regulator
CTZ40_RS15195	COG4585	Histidine kinase
CTZ40_RS15205	COG4176	ABC-type proline glycine betaine transport system permease component
CTZ40_RS15215	COG0517	IMP dehydrogenase activity
CTZ40_RS15215	COG4175	Glycine betaine
CTZ40_RS15225	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS15255	COG1476	TRANSCRIPTIONal
CTZ40_RS15280	COG0039	L-malate dehydrogenase activity
CTZ40_RS15315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CTZ40_RS15320	COG1714	RDD family
CTZ40_RS15330	COG0138	bifunctional purine biosynthesis protein purh
CTZ40_RS15365	COG0045	succinate-CoA ligase (ADP-forming) activity
CTZ40_RS15380	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CTZ40_RS15385	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CTZ40_RS15390	COG0714	Associated with various cellular activities
CTZ40_RS15405	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CTZ40_RS15450	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS15475	COG0789	Transcriptional regulator
CTZ40_RS15505	COG1309	transcriptional regulator
CTZ40_RS15515	COG2197	response regulator
CTZ40_RS15530	COG2815	serine threonine protein kinase
CTZ40_RS15530	COG0515	serine threonine protein kinase
CTZ40_RS15575	COG2084	Dehydrogenase
CTZ40_RS15590	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ40_RS15590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ40_RS15615	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS15620	COG0515	serine threonine protein kinase
CTZ40_RS15635	COG2197	response regulator
CTZ40_RS15640	COG4585	Histidine kinase
CTZ40_RS15690	COG1131	(ABC) transporter
CTZ40_RS15720	COG4821	SIS domain
CTZ40_RS15730	COG0259	pyridoxamine-phosphate oxidase activity
CTZ40_RS15750	COG1309	transcriptional regulator
CTZ40_RS15755	COG1024	Enoyl-CoA hydratase
CTZ40_RS15760	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS15775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ40_RS15810	COG2124	cytochrome p450
CTZ40_RS15820	COG5006	permease, DMT superfamily
CTZ40_RS15825	COG0583	DNA-binding transcription factor activity
CTZ40_RS15830	COG0247	lactate metabolic process
CTZ40_RS15830	COG0277	FAD linked oxidase domain protein
CTZ40_RS15840	COG2378	regulation of single-species biofilm formation
CTZ40_RS15845	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CTZ40_RS15880	COG0667	Aldo Keto reductase
CTZ40_RS15915	COG2252	PERMEase
CTZ40_RS15925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CTZ40_RS15945	COG2814	Major facilitator Superfamily
CTZ40_RS15955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTZ40_RS15960	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CTZ40_RS15965	COG1278	Cold shock
CTZ40_RS15980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS15985	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS15990	COG1120	ATPase activity
CTZ40_RS15995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTZ40_RS16015	COG1061	Type III restriction enzyme res subunit
CTZ40_RS16030	COG3973	AAA domain
CTZ40_RS16035	COG3142	Participates in the control of copper homeostasis
CTZ40_RS16070	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CTZ40_RS16075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CTZ40_RS16085	COG1115	amino acid carrier protein
CTZ40_RS16090	COG4221	oxidoreductase activity
CTZ40_RS16100	COG1278	Cold shock
CTZ40_RS16115	COG0463	Glycosyl transferase, family 2
CTZ40_RS16140	COG1940	carbohydrate kinase activity
CTZ40_RS16145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CTZ40_RS16170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CTZ40_RS16230	COG3708	Transcriptional regulator
CTZ40_RS16230	COG2207	Transcriptional regulator
CTZ40_RS16245	COG3842	ATPase activity
CTZ40_RS16255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CTZ40_RS16270	COG0215	cysteine-tRNA ligase activity
CTZ40_RS16275	COG3467	pyridoxamine 5'-phosphate
CTZ40_RS16280	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CTZ40_RS16285	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CTZ40_RS16290	COG1329	Transcriptional regulator
CTZ40_RS16310	COG5002	protein histidine kinase activity
CTZ40_RS16335	COG0367	asparagine synthase
CTZ40_RS16340	COG0588	phosphoglycerate mutase activity
CTZ40_RS16355	COG0438	transferase activity, transferring glycosyl groups
CTZ40_RS16370	COG0667	Aldo Keto reductase
CTZ40_RS16390	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CTZ40_RS16410	COG0456	acetyltransferase
CTZ40_RS16415	COG0737	Belongs to the 5'-nucleotidase family
CTZ40_RS16460	COG0702	epimerase
CTZ40_RS16475	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS16485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ40_RS16490	COG1609	Transcriptional regulator
CTZ40_RS16495	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS16530	COG2897	thiosulfate sulfurtransferase activity
CTZ40_RS16550	COG3485	protocatechuate 3,4-dioxygenase
CTZ40_RS16555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS16560	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CTZ40_RS16570	COG0735	belongs to the Fur family
CTZ40_RS16575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CTZ40_RS16580	COG1490	D-aminoacyl-tRNA deacylase activity
CTZ40_RS16595	COG4552	Acetyltransferase involved in intracellular survival and related
CTZ40_RS16610	COG1733	regulation of RNA biosynthetic process
CTZ40_RS16625	COG2890	protein-(glutamine-N5) methyltransferase activity
CTZ40_RS16635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ40_RS16660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTZ40_RS16670	COG1733	regulation of RNA biosynthetic process
CTZ40_RS16675	COG0604	alcohol dehydrogenase
CTZ40_RS16710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTZ40_RS16730	COG0306	phosphate transporter
CTZ40_RS16740	COG1937	Protein conserved in bacteria
CTZ40_RS16760	COG0277	FAD linked oxidase domain protein
CTZ40_RS16770	COG0671	phosphoesterase, PA-phosphatase related
CTZ40_RS16775	COG0791	NLP P60 protein
CTZ40_RS16860	COG0180	Tryptophanyl-tRNA synthetase
CTZ40_RS16865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CTZ40_RS16885	COG0659	secondary active sulfate transmembrane transporter activity
CTZ40_RS16890	COG0308	aminopeptidase N
CTZ40_RS16895	COG2226	methyltransferase
CTZ40_RS16930	COG0129	dihydroxy-acid dehydratase activity
CTZ40_RS16940	COG1082	Xylose isomerase domain protein TIM barrel
CTZ40_RS16945	COG0248	Ppx GppA phosphatase
CTZ40_RS16965	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CTZ40_RS16980	COG0671	phosphoesterase, PA-phosphatase related
CTZ40_RS16990	COG1194	a g-specific adenine glycosylase
CTZ40_RS16995	COG1595	DNA-templated transcription, initiation
CTZ40_RS17005	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS17010	COG2205	protein histidine kinase activity
CTZ40_RS17015	COG0346	lactoylglutathione lyase activity
CTZ40_RS17020	COG2207	Transcriptional regulator
CTZ40_RS17020	COG4753	response regulator
CTZ40_RS17035	COG1196	nuclear chromosome segregation
CTZ40_RS17035	COG0739	heme binding
CTZ40_RS17035	COG0741	lytic transglycosylase activity
CTZ40_RS17065	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CTZ40_RS17085	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CTZ40_RS17095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CTZ40_RS17100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CTZ40_RS17115	COG0640	Transcriptional regulator
CTZ40_RS17145	COG0649	NAD binding
CTZ40_RS17160	COG3226	Transcriptional regulator
CTZ40_RS17170	COG1309	transcriptional regulator
CTZ40_RS17175	COG2814	Major facilitator Superfamily
CTZ40_RS17185	COG1732	Glycine betaine
CTZ40_RS17190	COG1174	glycine betaine transport
CTZ40_RS17195	COG1174	glycine betaine transport
CTZ40_RS17200	COG1125	glycine betaine transport
CTZ40_RS17200	COG0517	IMP dehydrogenase activity
CTZ40_RS17210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTZ40_RS17215	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CTZ40_RS17230	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CTZ40_RS17230	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CTZ40_RS17240	COG0302	gtp cyclohydrolase
CTZ40_RS17255	COG0037	tRNA processing
CTZ40_RS17265	COG2027	D-alanyl-D-alanine carboxypeptidase
CTZ40_RS17270	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTZ40_RS17285	COG0393	Putative heavy-metal-binding
CTZ40_RS17290	COG0789	Transcriptional regulator
CTZ40_RS17330	COG0655	NAD(P)H dehydrogenase (quinone) activity
CTZ40_RS17335	COG0076	glutamate decarboxylase activity
CTZ40_RS17355	COG2318	DinB family
CTZ40_RS17360	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS17380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CTZ40_RS17390	COG0254	rRNA binding
CTZ40_RS17400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CTZ40_RS17405	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CTZ40_RS17415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ40_RS17415	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTZ40_RS17430	COG3655	Transcriptional regulator
CTZ40_RS17435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTZ40_RS17435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTZ40_RS17440	COG0657	acetylesterase activity
CTZ40_RS17445	COG1309	transcriptional regulator
CTZ40_RS17455	COG1349	DNA-binding transcription factor activity
CTZ40_RS17490	COG2197	response regulator
CTZ40_RS17495	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ40_RS17520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CTZ40_RS17525	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CTZ40_RS17540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS17555	COG1132	(ABC) transporter
CTZ40_RS17560	COG2366	antibiotic biosynthetic process
CTZ40_RS17575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTZ40_RS17580	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CTZ40_RS17590	COG1754	DNA topoisomerase type I activity
CTZ40_RS17590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CTZ40_RS17610	COG2890	protein-(glutamine-N5) methyltransferase activity
CTZ40_RS17620	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CTZ40_RS17635	COG1366	Belongs to the anti-sigma-factor antagonist family
CTZ40_RS17640	COG1111	helicase
CTZ40_RS17640	COG1205	dead DEAH box helicase
CTZ40_RS17650	COG1917	Cupin 2, conserved barrel domain protein
CTZ40_RS17715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ40_RS17720	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CTZ40_RS17730	COG2267	carboxylic ester hydrolase activity
CTZ40_RS17760	COG2957	Belongs to the agmatine deiminase family
CTZ40_RS17770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ40_RS17795	COG0003	Pfam Anion-transporting ATPase
CTZ40_RS17805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ40_RS17815	COG1408	metallophosphoesterase
CTZ40_RS17865	COG4106	trans-aconitate 2-methyltransferase activity
CTZ40_RS17880	COG1819	glycosyl
CTZ40_RS17890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTZ40_RS17895	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS17900	COG2030	dehydratase
CTZ40_RS17915	COG0515	serine threonine protein kinase
CTZ40_RS17920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTZ40_RS17930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ40_RS18040	COG1357	PFAM Pentapeptide repeats (8 copies)
CTZ40_RS18055	COG1595	DNA-templated transcription, initiation
CTZ40_RS18075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTZ40_RS18080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CTZ40_RS18115	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ40_RS18120	COG1595	DNA-templated transcription, initiation
CTZ40_RS18140	COG0402	S-adenosylhomocysteine deaminase activity
CTZ40_RS18170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CTZ40_RS18175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CTZ40_RS18180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ40_RS18185	COG1609	Transcriptional regulator
CTZ40_RS18195	COG1309	transcriptional regulator
CTZ40_RS18210	COG0488	(ABC) transporter
CTZ40_RS18225	COG4552	Acetyltransferase involved in intracellular survival and related
CTZ40_RS18230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTZ40_RS18235	COG0463	Glycosyl transferase, family 2
CTZ40_RS18245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ40_RS18265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ40_RS18275	COG1940	carbohydrate kinase activity
CTZ40_RS18280	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ40_RS18315	COG0523	cobalamin synthesis protein
CTZ40_RS18350	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CTZ40_RS18375	COG0657	acetylesterase activity
CTZ40_RS18415	COG0640	Transcriptional regulator
CTZ40_RS18425	COG1191	sigma factor activity
CTZ40_RS18430	COG1191	sigma factor activity
CTZ40_RS18440	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ40_RS18460	COG1595	DNA-templated transcription, initiation
CTZ40_RS18495	COG0110	maltose O-acetyltransferase activity
CTZ40_RS18545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ40_RS18555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ40_RS18595	COG0477	Major facilitator Superfamily
CTZ40_RS18600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CTZ40_RS18610	COG2205	protein histidine kinase activity
CTZ40_RS18615	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS18640	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ40_RS18665	COG1609	Transcriptional regulator
CTZ40_RS18745	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS18800	COG1595	DNA-templated transcription, initiation
CTZ40_RS18835	COG0457	Tetratricopeptide repeat
CTZ40_RS18860	COG2188	Transcriptional regulator
CTZ40_RS18990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ40_RS19030	COG0006	proline dipeptidase activity
CTZ40_RS19065	COG2372	response to copper ion
CTZ40_RS19070	COG2837	iron assimilation
CTZ40_RS19080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CTZ40_RS19085	COG0561	phosphatase activity
CTZ40_RS19115	COG0789	Transcriptional regulator
CTZ40_RS19130	COG2186	Transcriptional regulator
CTZ40_RS19135	COG2807	transmembrane transport
CTZ40_RS19145	COG0789	Transcriptional regulator
CTZ40_RS19180	COG1131	(ABC) transporter
CTZ40_RS19200	COG0789	Transcriptional regulator
CTZ40_RS19215	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CTZ40_RS19240	COG0501	Belongs to the peptidase M48B family
CTZ40_RS19250	COG0561	phosphatase activity
CTZ40_RS19255	COG0739	heme binding
CTZ40_RS19265	COG4988	ABC transporter
CTZ40_RS19270	COG1294	oxidase, subunit
CTZ40_RS19275	COG1271	oxidase subunit
CTZ40_RS19285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CTZ40_RS19290	COG1609	Transcriptional regulator
CTZ40_RS19295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTZ40_RS19315	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CTZ40_RS19340	COG0662	Cupin 2, conserved barrel domain protein
CTZ40_RS19345	COG1950	PFAM Membrane protein of
CTZ40_RS19350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTZ40_RS19355	COG0626	cystathionine gamma-synthase activity
CTZ40_RS19395	COG2814	Major facilitator Superfamily
CTZ40_RS19400	COG1846	Transcriptional regulator
CTZ40_RS19435	COG4978	Transcriptional regulator
CTZ40_RS19435	COG0789	Transcriptional regulator
CTZ40_RS19460	COG0242	peptide deformylase activity
CTZ40_RS19465	COG1309	transcriptional regulator
CTZ40_RS19480	COG0305	Participates in initiation and elongation during chromosome replication
CTZ40_RS19485	COG0534	Mate efflux family protein
CTZ40_RS19495	COG0359	binds to the 23S rRNA
CTZ40_RS19500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CTZ40_RS19505	COG0629	single-stranded DNA binding
CTZ40_RS19510	COG0360	Binds together with S18 to 16S ribosomal RNA
CTZ40_RS19535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ40_RS19540	COG1695	Transcriptional regulator
CTZ40_RS19560	COG0617	tRNA 3'-terminal CCA addition
CTZ40_RS19585	COG1595	DNA-templated transcription, initiation
CTZ40_RS19595	COG0492	ferredoxin-NADP+ reductase activity
CTZ40_RS19600	COG3118	belongs to the thioredoxin family
CTZ40_RS19615	COG1192	Involved in chromosome partitioning
CTZ40_RS19620	COG0357	Ribosomal RNA small subunit methyltransferase G
CTZ40_RS19630	COG0706	membrane insertase activity
CTZ40_RS19635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CTZ40_RS19645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CTZ40_RS19650	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CTZ40_RS19660	COG0592	DNA-directed DNA polymerase activity
CTZ40_RS19665	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CTZ40_RS19670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CTZ40_RS19675	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CTZ40_RS19685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CTZ40_RS19710	COG0515	serine threonine protein kinase
CTZ40_RS19735	COG0705	Rhomboid family
CTZ40_RS19750	COG3764	Sortase (surface protein transpeptidase)
CTZ40_RS19760	COG3764	Sortase (surface protein transpeptidase)
CTZ40_RS19765	COG3764	Sortase (surface protein transpeptidase)
CTZ40_RS19770	COG0515	serine threonine protein kinase
CTZ40_RS19780	COG0768	penicillin binding
CTZ40_RS19795	COG1716	ATPase activity
CTZ40_RS19800	COG1716	ATPase activity
CTZ40_RS19810	COG0583	DNA-binding transcription factor activity
CTZ40_RS19820	COG4585	Histidine kinase
CTZ40_RS19825	COG2197	response regulator
CTZ40_RS19830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTZ40_RS19835	COG1733	regulation of RNA biosynthetic process
CTZ40_RS19870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ40_RS19875	COG2151	metal-sulfur cluster biosynthetic enzyme
CTZ40_RS19880	COG3396	Phenylacetate-CoA oxygenase
CTZ40_RS19885	COG3460	Phenylacetate-CoA oxygenase
CTZ40_RS19890	COG3396	Phenylacetate-CoA oxygenase
CTZ40_RS19950	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ40_RS19955	COG1309	transcriptional regulator
CTZ40_RS19960	COG1522	sequence-specific DNA binding
CTZ40_RS19980	COG0746	molybdenum cofactor guanylyltransferase activity
CTZ40_RS19985	COG0303	'Molybdopterin
CTZ40_RS19990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ40_RS19995	COG3321	synthase
CTZ40_RS19995	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS19995	COG0604	alcohol dehydrogenase
CTZ40_RS20010	COG0515	serine threonine protein kinase
CTZ40_RS20015	COG0515	serine threonine protein kinase
CTZ40_RS20040	COG0022	dehydrogenase e1 component
CTZ40_RS20045	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ40_RS20095	COG0477	Major facilitator Superfamily
CTZ40_RS20120	COG1802	Transcriptional regulator
CTZ40_RS20180	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ40_RS20195	COG3903	Transcriptional regulator
CTZ40_RS20195	COG3629	intracellular signal transduction
CTZ40_RS20200	COG1362	aminopeptidase activity
CTZ40_RS20205	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS20220	COG1741	Belongs to the pirin family
CTZ40_RS20225	COG0628	permease
CTZ40_RS20235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CTZ40_RS20250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ40_RS20255	COG2226	methyltransferase
CTZ40_RS20280	COG1174	glycine betaine transport
CTZ40_RS20285	COG1174	glycine betaine transport
CTZ40_RS20295	COG1125	glycine betaine transport
CTZ40_RS20295	COG0517	IMP dehydrogenase activity
CTZ40_RS20385	COG1316	TRANSCRIPTIONal
CTZ40_RS20425	COG0477	Major facilitator Superfamily
CTZ40_RS20445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTZ40_RS20460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ40_RS20475	COG2197	response regulator
CTZ40_RS20485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ40_RS20495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS20515	COG3629	intracellular signal transduction
CTZ40_RS20525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ40_RS20540	COG0789	Transcriptional regulator
CTZ40_RS20555	COG3321	synthase
CTZ40_RS20555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS20580	COG5635	Nacht domain
CTZ40_RS20580	COG2319	Wd-40 repeat
CTZ40_RS20630	COG0717	Belongs to the dCTP deaminase family
CTZ40_RS20665	COG0247	lactate metabolic process
CTZ40_RS20665	COG2181	nitrate reductase activity
CTZ40_RS20670	COG0443	Heat shock 70 kDa protein
CTZ40_RS20675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CTZ40_RS20680	COG0484	heat shock protein binding
CTZ40_RS20685	COG0789	Transcriptional regulator
CTZ40_RS20705	COG0542	response to heat
CTZ40_RS20740	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CTZ40_RS20755	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CTZ40_RS20760	COG0191	fructose-bisphosphate aldolase activity
CTZ40_RS20770	COG3483	tryptophan 2,3-dioxygenase activity
CTZ40_RS20775	COG0657	acetylesterase activity
CTZ40_RS20780	COG4585	Histidine kinase
CTZ40_RS20785	COG2197	response regulator
CTZ40_RS20800	COG3559	Exporter of polyketide antibiotics
CTZ40_RS20805	COG1131	(ABC) transporter
CTZ40_RS20820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTZ40_RS20835	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CTZ40_RS20860	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CTZ40_RS20880	COG0693	protein deglycase activity
CTZ40_RS20890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ40_RS20895	COG1802	Transcriptional regulator
CTZ40_RS20910	COG0151	Belongs to the GarS family
CTZ40_RS20925	COG0583	DNA-binding transcription factor activity
CTZ40_RS20930	COG2814	Major facilitator Superfamily
CTZ40_RS20935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CTZ40_RS20950	COG3850	Histidine kinase
CTZ40_RS20985	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTZ40_RS20990	COG0047	phosphoribosylformylglycinamidine synthase activity
CTZ40_RS20995	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTZ40_RS21055	COG1643	Atp-dependent helicase
CTZ40_RS21090	COG0513	Belongs to the DEAD box helicase family
CTZ40_RS21140	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CTZ40_RS21215	COG2814	Major facilitator Superfamily
CTZ40_RS21220	COG0667	Aldo Keto reductase
CTZ40_RS21260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTZ40_RS21265	COG0579	oxidoreductase
CTZ40_RS21290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ40_RS21325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ40_RS21330	COG0123	including yeast histone deacetylase and acetoin utilization protein
CTZ40_RS21385	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CTZ40_RS21390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CTZ40_RS21395	COG0181	hydroxymethylbilane synthase activity
CTZ40_RS21400	COG1648	precorrin-2 dehydrogenase activity
CTZ40_RS21400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTZ40_RS21405	COG0113	porphobilinogen synthase activity
CTZ40_RS21445	COG2814	Major facilitator Superfamily
CTZ40_RS21470	COG0018	arginyl-trna synthetase
CTZ40_RS21475	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CTZ40_RS21540	COG1690	Belongs to the RtcB family
CTZ40_RS21560	COG1742	UPF0060 membrane protein
CTZ40_RS21570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ40_RS21585	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS21600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ40_RS21610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CTZ40_RS21615	COG0406	alpha-ribazole phosphatase activity
CTZ40_RS21630	COG0785	Cytochrome C biogenesis protein
CTZ40_RS21635	COG1333	cytochrome c biogenesis protein
CTZ40_RS21640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CTZ40_RS21690	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CTZ40_RS21695	COG0109	protoheme IX farnesyltransferase activity
CTZ40_RS21710	COG0163	prenyltransferase activity
CTZ40_RS21720	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CTZ40_RS21735	COG1823	symporter activity
CTZ40_RS21750	COG1309	transcriptional regulator
CTZ40_RS21775	COG1278	Cold shock
CTZ40_RS21780	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CTZ40_RS21785	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CTZ40_RS21795	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CTZ40_RS21810	COG2226	methyltransferase
CTZ40_RS21850	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ40_RS21855	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ40_RS21860	COG0649	NAD binding
CTZ40_RS21870	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTZ40_RS21875	COG1034	ATP synthesis coupled electron transport
CTZ40_RS21880	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CTZ40_RS21885	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ40_RS21890	COG0839	Belongs to the complex I subunit 6 family
CTZ40_RS21895	COG0713	ATP synthesis coupled electron transport
CTZ40_RS21900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ40_RS21910	COG1007	ATP synthesis coupled electron transport
CTZ40_RS21940	COG0492	ferredoxin-NADP+ reductase activity
CTZ40_RS21945	COG0142	geranyltranstransferase activity
CTZ40_RS21965	COG2234	aminopeptidase activity
CTZ40_RS21965	COG4935	Belongs to the peptidase S8 family
CTZ40_RS21975	COG1013	pyruvate-flavodoxin oxidoreductase activity
CTZ40_RS21980	COG0674	pyruvate-flavodoxin oxidoreductase activity
CTZ40_RS21980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CTZ40_RS21990	COG4585	Histidine kinase
CTZ40_RS21995	COG4585	Histidine kinase
CTZ40_RS22015	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ40_RS22020	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ40_RS22025	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ40_RS22030	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CTZ40_RS22035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ40_RS22040	COG0839	Belongs to the complex I subunit 6 family
CTZ40_RS22045	COG0713	ATP synthesis coupled electron transport
CTZ40_RS22050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ40_RS22060	COG1007	ATP synthesis coupled electron transport
CTZ40_RS22065	COG0501	Belongs to the peptidase M48B family
CTZ40_RS22070	COG3304	Inner membrane component domain
CTZ40_RS22080	COG1666	GTP binding
CTZ40_RS22090	COG0702	epimerase
CTZ40_RS22110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CTZ40_RS22115	COG2030	dehydratase
CTZ40_RS22125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CTZ40_RS22130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ40_RS22135	COG0436	Aminotransferase
CTZ40_RS22155	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CTZ40_RS22160	COG0081	regulation of translation
CTZ40_RS22170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CTZ40_RS22175	COG0222	ribosome binding
CTZ40_RS22185	COG0085	RNA polymerase activity
CTZ40_RS22190	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CTZ40_RS22200	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CTZ40_RS22205	COG0049	tRNA binding
CTZ40_RS22210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CTZ40_RS22215	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CTZ40_RS22220	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CTZ40_RS22245	COG0051	transcription antitermination factor activity, RNA binding
CTZ40_RS22250	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CTZ40_RS22255	COG0088	Forms part of the polypeptide exit tunnel
CTZ40_RS22260	COG0089	rRNA binding
CTZ40_RS22265	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CTZ40_RS22270	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CTZ40_RS22275	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CTZ40_RS22280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CTZ40_RS22285	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CTZ40_RS22290	COG0255	Belongs to the universal ribosomal protein uL29 family
CTZ40_RS22295	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CTZ40_RS22300	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CTZ40_RS22305	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CTZ40_RS22310	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CTZ40_RS22315	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CTZ40_RS22325	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CTZ40_RS22330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CTZ40_RS22335	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CTZ40_RS22340	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CTZ40_RS22345	COG1841	ribosomal large subunit assembly
CTZ40_RS22350	COG0200	Binds to the 23S rRNA
CTZ40_RS22360	COG0563	adenylate kinase activity
CTZ40_RS22370	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CTZ40_RS22375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CTZ40_RS22380	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CTZ40_RS22385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CTZ40_RS22390	COG0202	RNA polymerase activity
CTZ40_RS22395	COG0203	ribosomal protein L17
CTZ40_RS22400	COG0101	tRNA pseudouridine synthase activity
CTZ40_RS22415	COG0488	(ABC) transporter
CTZ40_RS22425	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CTZ40_RS22430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTZ40_RS22435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ40_RS22445	COG1072	(Pantothenic acid kinase))
CTZ40_RS22450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ40_RS22455	COG0736	holo-[acyl-carrier-protein] synthase activity
CTZ40_RS22465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTZ40_RS22475	COG0802	atpase or kinase
CTZ40_RS22500	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CTZ40_RS22520	COG0772	Belongs to the SEDS family
CTZ40_RS22525	COG1316	TRANSCRIPTIONal
CTZ40_RS22530	COG2205	protein histidine kinase activity
CTZ40_RS22535	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS22540	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CTZ40_RS22545	COG0459	protein refolding
CTZ40_RS22570	COG1609	Transcriptional regulator
CTZ40_RS22580	COG4221	oxidoreductase activity
CTZ40_RS22590	COG0583	DNA-binding transcription factor activity
CTZ40_RS22600	COG2197	response regulator
CTZ40_RS22605	COG1595	DNA-templated transcription, initiation
CTZ40_RS22620	COG0516	GMP reductase activity
CTZ40_RS22635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CTZ40_RS22655	COG0477	Major facilitator Superfamily
CTZ40_RS22660	COG0583	DNA-binding transcription factor activity
CTZ40_RS22670	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS22675	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS22690	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS22695	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS22705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ40_RS22710	COG1024	Enoyl-CoA hydratase
CTZ40_RS22720	COG2072	flavoprotein involved in K transport
CTZ40_RS22825	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS22835	COG1309	transcriptional regulator
CTZ40_RS22845	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ40_RS22845	COG0515	serine threonine protein kinase
CTZ40_RS22865	COG1024	Enoyl-CoA hydratase
CTZ40_RS22940	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CTZ40_RS22960	COG0492	ferredoxin-NADP+ reductase activity
CTZ40_RS23000	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CTZ40_RS23055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ40_RS23080	COG1686	Belongs to the peptidase S11 family
CTZ40_RS23090	COG0640	Transcriptional regulator
CTZ40_RS23115	COG2205	protein histidine kinase activity
CTZ40_RS23145	COG0514	ATP-dependent DNA helicase (RecQ)
CTZ40_RS23165	COG1595	DNA-templated transcription, initiation
CTZ40_RS23410	COG1674	ftsk spoiiie
CTZ40_RS23585	COG5280	Phage tail tape measure protein TP901
CTZ40_RS23585	COG3953	SLT domain
CTZ40_RS23665	COG0659	secondary active sulfate transmembrane transporter activity
CTZ40_RS23680	COG0477	Major facilitator Superfamily
CTZ40_RS23740	COG1309	transcriptional regulator
CTZ40_RS23775	COG1846	Transcriptional regulator
CTZ40_RS23795	COG1247	-acetyltransferase
CTZ40_RS23805	COG1349	DNA-binding transcription factor activity
CTZ40_RS23825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ40_RS23840	COG3191	aminopeptidase activity
CTZ40_RS23855	COG1473	amidohydrolase
CTZ40_RS23880	COG0730	response to heat
CTZ40_RS23885	COG2188	Transcriptional regulator
CTZ40_RS23890	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CTZ40_RS23895	COG0477	Major facilitator Superfamily
CTZ40_RS23920	COG1970	mechanosensitive ion channel activity
CTZ40_RS23930	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CTZ40_RS23940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CTZ40_RS23945	COG3263	regulation of cellular component size
CTZ40_RS23950	COG2366	antibiotic biosynthetic process
CTZ40_RS23955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTZ40_RS23960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTZ40_RS23970	COG0315	cyclic pyranopterin monophosphate synthase activity
CTZ40_RS23975	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTZ40_RS23980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTZ40_RS24000	COG0739	heme binding
CTZ40_RS24005	COG1609	Transcriptional regulator
CTZ40_RS24015	COG1175	transmembrane transport
CTZ40_RS24020	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS24040	COG1819	glycosyl
CTZ40_RS24045	COG0789	Transcriptional regulator
CTZ40_RS24055	COG2205	protein histidine kinase activity
CTZ40_RS24075	COG0708	Exodeoxyribonuclease III
CTZ40_RS24140	COG1733	regulation of RNA biosynthetic process
CTZ40_RS24145	COG0251	oxidation-reduction process
CTZ40_RS24150	COG1335	isochorismatase
CTZ40_RS24160	COG2072	flavoprotein involved in K transport
CTZ40_RS24165	COG2267	carboxylic ester hydrolase activity
CTZ40_RS24170	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS24180	COG4946	Tricorn protease homolog
CTZ40_RS24180	COG0793	Belongs to the peptidase S41A family
CTZ40_RS24190	COG2409	Drug exporters of the RND superfamily
CTZ40_RS24205	COG0310	cobalt ion transport
CTZ40_RS24215	COG1122	ATPase activity
CTZ40_RS24220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ40_RS24225	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS24235	COG0768	penicillin binding
CTZ40_RS24260	COG0084	hydrolase, TatD family'
CTZ40_RS24265	COG3584	3D domain protein
CTZ40_RS24265	COG3583	domain protein
CTZ40_RS24270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTZ40_RS24275	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CTZ40_RS24285	COG0488	(ABC) transporter
CTZ40_RS24315	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CTZ40_RS24320	COG2197	response regulator
CTZ40_RS24340	COG4106	trans-aconitate 2-methyltransferase activity
CTZ40_RS24350	COG1309	transcriptional regulator
CTZ40_RS24360	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CTZ40_RS24375	COG0193	aminoacyl-tRNA hydrolase activity
CTZ40_RS24380	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CTZ40_RS24385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ40_RS24390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CTZ40_RS24405	COG4585	Histidine kinase
CTZ40_RS24430	COG1316	TRANSCRIPTIONal
CTZ40_RS24440	COG2814	Major facilitator Superfamily
CTZ40_RS24455	COG3896	Chloramphenicol phosphotransferase-like protein
CTZ40_RS24480	COG2814	Major facilitator Superfamily
CTZ40_RS24485	COG0583	DNA-binding transcription factor activity
CTZ40_RS24495	COG2124	cytochrome p450
CTZ40_RS24510	COG0148	phosphopyruvate hydratase activity
CTZ40_RS24535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTZ40_RS24540	COG0577	efflux transmembrane transporter activity
CTZ40_RS24545	COG1136	(ABC) transporter
CTZ40_RS24610	COG0183	Belongs to the thiolase family
CTZ40_RS24615	COG2755	lipolytic protein G-D-S-L family
CTZ40_RS24630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ40_RS24645	COG1609	Transcriptional regulator
CTZ40_RS24660	COG0596	Alpha beta hydrolase
CTZ40_RS24685	COG0019	diaminopimelate decarboxylase activity
CTZ40_RS24690	COG2022	thiamine diphosphate biosynthetic process
CTZ40_RS24690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ40_RS24705	COG3938	Belongs to the proline racemase family
CTZ40_RS24715	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CTZ40_RS24720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTZ40_RS24725	COG0402	S-adenosylhomocysteine deaminase activity
CTZ40_RS24730	COG1228	amidohydrolase
CTZ40_RS24740	COG2197	response regulator
CTZ40_RS24750	COG3963	phosphatidate phosphatase activity
CTZ40_RS24755	COG1191	sigma factor activity
CTZ40_RS24760	COG1366	Belongs to the anti-sigma-factor antagonist family
CTZ40_RS24790	COG3104	oligopeptide transport
CTZ40_RS24795	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS24800	COG5002	protein histidine kinase activity
CTZ40_RS24835	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CTZ40_RS24865	COG1316	TRANSCRIPTIONal
CTZ40_RS24870	COG1607	acyl-coa hydrolase
CTZ40_RS24890	COG0477	Major facilitator Superfamily
CTZ40_RS24935	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CTZ40_RS24935	COG0778	Nitroreductase
CTZ40_RS24940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CTZ40_RS24980	COG1620	l-lactate permease
CTZ40_RS24985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ40_RS24990	COG2835	tetraacyldisaccharide 4'-kinase activity
CTZ40_RS25000	COG1482	cell wall glycoprotein biosynthetic process
CTZ40_RS25010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTZ40_RS25010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTZ40_RS25010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTZ40_RS25015	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTZ40_RS25060	COG0714	Associated with various cellular activities
CTZ40_RS25080	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CTZ40_RS25085	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS25090	COG5000	phosphorelay sensor kinase activity
CTZ40_RS25090	COG5002	protein histidine kinase activity
CTZ40_RS25095	COG0823	Involved in the tonB-independent uptake of proteins
CTZ40_RS25115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CTZ40_RS25120	COG2197	response regulator
CTZ40_RS25130	COG0653	protein targeting
CTZ40_RS25160	COG1134	teichoic acid transport
CTZ40_RS25170	COG1309	transcriptional regulator
CTZ40_RS25185	COG0463	Glycosyl transferase, family 2
CTZ40_RS25195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CTZ40_RS25200	COG0438	transferase activity, transferring glycosyl groups
CTZ40_RS25205	COG0463	Glycosyl transferase, family 2
CTZ40_RS25215	COG1215	transferase activity, transferring glycosyl groups
CTZ40_RS25220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CTZ40_RS25230	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS25235	COG1175	transmembrane transport
CTZ40_RS25240	COG1653	transport
CTZ40_RS25245	COG1674	ftsk spoiiie
CTZ40_RS25250	COG0515	serine threonine protein kinase
CTZ40_RS25255	COG0515	serine threonine protein kinase
CTZ40_RS25260	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CTZ40_RS25275	COG2884	Cell division ATP-binding protein ftsE
CTZ40_RS25280	COG2177	Part of the ABC transporter FtsEX involved in
CTZ40_RS25285	COG0793	Belongs to the peptidase S41A family
CTZ40_RS25290	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CTZ40_RS25335	COG2223	nitrite transmembrane transporter activity
CTZ40_RS25365	COG3973	AAA domain
CTZ40_RS25380	COG0776	regulation of translation
CTZ40_RS25385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CTZ40_RS25390	COG1678	Uncharacterized ACR, COG1678
CTZ40_RS25395	COG0583	DNA-binding transcription factor activity
CTZ40_RS25405	COG2814	Major facilitator Superfamily
CTZ40_RS25425	COG1175	transmembrane transport
CTZ40_RS25430	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS25435	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CTZ40_RS25450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTZ40_RS25470	COG2201	protein-glutamate methylesterase activity
CTZ40_RS25475	COG0477	Major facilitator Superfamily
CTZ40_RS25495	COG1732	Glycine betaine
CTZ40_RS25500	COG1174	glycine betaine transport
CTZ40_RS25510	COG1174	glycine betaine transport
CTZ40_RS25520	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CTZ40_RS25525	COG0277	FAD linked oxidase domain protein
CTZ40_RS25530	COG0222	ribosome binding
CTZ40_RS25575	COG1335	isochorismatase
CTZ40_RS25585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTZ40_RS25595	COG1113	amino acid transport
CTZ40_RS25610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS25615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CTZ40_RS25635	COG1234	tRNA 3'-trailer cleavage
CTZ40_RS25640	COG1263	PTS System
CTZ40_RS25645	COG1263	PTS System
CTZ40_RS25650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTZ40_RS25655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CTZ40_RS25670	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CTZ40_RS25700	COG2205	protein histidine kinase activity
CTZ40_RS25715	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CTZ40_RS25725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ40_RS25755	COG2733	membrane
CTZ40_RS25760	COG3764	Sortase (surface protein transpeptidase)
CTZ40_RS25770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ40_RS25780	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTZ40_RS25800	COG0706	membrane insertase activity
CTZ40_RS25805	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTZ40_RS25815	COG4702	Belongs to the UPF0303 family
CTZ40_RS25820	COG0673	inositol 2-dehydrogenase activity
CTZ40_RS25835	COG2188	Transcriptional regulator
CTZ40_RS25865	COG1840	ABC-type Fe3 transport system, periplasmic component
CTZ40_RS25905	COG2186	Transcriptional regulator
CTZ40_RS25935	COG3397	chitin binding
CTZ40_RS25940	COG3397	chitin binding
CTZ40_RS25955	COG1126	abc transporter atp-binding protein
CTZ40_RS25960	COG0765	amino acid transport
CTZ40_RS25965	COG0765	amino acid transport
CTZ40_RS25980	COG0154	amidase activity
CTZ40_RS26000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ40_RS26050	COG0588	phosphoglycerate mutase activity
CTZ40_RS26085	COG3979	chitinase
CTZ40_RS26115	COG5297	Belongs to the glycosyl hydrolase family 6
CTZ40_RS26130	COG2910	NAD(P)H-binding
CTZ40_RS26140	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTZ40_RS26145	COG4977	sequence-specific DNA binding
CTZ40_RS26155	COG0589	response to stress
CTZ40_RS26160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ40_RS26175	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS26190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ40_RS26195	COG1309	transcriptional regulator
CTZ40_RS26205	COG1946	Acyl-CoA thioesterase
CTZ40_RS26250	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CTZ40_RS26260	COG0281	malic enzyme
CTZ40_RS26265	COG1309	transcriptional regulator
CTZ40_RS26270	COG1511	domain protein
CTZ40_RS26275	COG1132	(ABC) transporter
CTZ40_RS26310	COG1472	Belongs to the glycosyl hydrolase 3 family
CTZ40_RS26325	COG1609	Transcriptional regulator
CTZ40_RS26330	COG0673	inositol 2-dehydrogenase activity
CTZ40_RS26345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ40_RS26365	COG0569	domain protein
CTZ40_RS26365	COG0475	glutathione-regulated potassium exporter activity
CTZ40_RS26375	COG0673	inositol 2-dehydrogenase activity
CTZ40_RS26390	COG2814	Major facilitator Superfamily
CTZ40_RS26395	COG1082	Xylose isomerase domain protein TIM barrel
CTZ40_RS26400	COG0673	inositol 2-dehydrogenase activity
CTZ40_RS26410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ40_RS26420	COG3718	enzyme involved in inositol metabolism
CTZ40_RS26425	COG3962	Belongs to the TPP enzyme family
CTZ40_RS26445	COG1131	(ABC) transporter
CTZ40_RS26475	COG1077	Cell shape determining protein MreB Mrl
CTZ40_RS26580	COG1160	GTP binding
CTZ40_RS26585	COG0629	single-stranded DNA binding
CTZ40_RS26615	COG2346	COG2346, Truncated hemoglobins
CTZ40_RS26620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ40_RS26650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ40_RS26665	COG1486	melibiose metabolic process
CTZ40_RS26670	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS26675	COG1175	transmembrane transport
CTZ40_RS26690	COG1940	carbohydrate kinase activity
CTZ40_RS26690	COG1846	Transcriptional regulator
CTZ40_RS26720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTZ40_RS26725	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CTZ40_RS26730	COG2080	2 iron, 2 sulfur cluster binding
CTZ40_RS26760	COG0668	transmembrane transport
CTZ40_RS26770	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CTZ40_RS26770	COG3291	Pkd domain containing protein
CTZ40_RS26800	COG0583	DNA-binding transcription factor activity
CTZ40_RS26805	COG4266	Belongs to the allantoicase family
CTZ40_RS26825	COG2337	Toxic component of a toxin-antitoxin (TA) module
CTZ40_RS26860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTZ40_RS26865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTZ40_RS26870	COG1113	amino acid transport
CTZ40_RS26875	COG1113	amino acid transport
CTZ40_RS26880	COG1268	BioY protein
CTZ40_RS26890	COG0515	serine threonine protein kinase
CTZ40_RS26910	COG4552	Acetyltransferase involved in intracellular survival and related
CTZ40_RS26925	COG0475	glutathione-regulated potassium exporter activity
CTZ40_RS26930	COG1136	(ABC) transporter
CTZ40_RS26935	COG3594	Acyltransferase
CTZ40_RS26960	COG0544	peptidyl-prolyl cis-trans isomerase activity
CTZ40_RS26965	COG0740	serine-type endopeptidase activity
CTZ40_RS26970	COG0740	serine-type endopeptidase activity
CTZ40_RS26975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CTZ40_RS26990	COG0525	valine-tRNA ligase activity
CTZ40_RS27000	COG0768	penicillin binding
CTZ40_RS27005	COG0285	dihydrofolate synthase activity
CTZ40_RS27015	COG0105	UTP biosynthetic process
CTZ40_RS27020	COG1077	Cell shape determining protein MreB Mrl
CTZ40_RS27040	COG0772	Belongs to the SEDS family
CTZ40_RS27050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTZ40_RS27060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ40_RS27060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ40_RS27085	COG1530	ribonuclease E activity
CTZ40_RS27090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CTZ40_RS27095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CTZ40_RS27100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CTZ40_RS27105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CTZ40_RS27115	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CTZ40_RS27130	COG0501	Belongs to the peptidase M48B family
CTZ40_RS27140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CTZ40_RS27150	COG0799	negative regulation of ribosome biogenesis
CTZ40_RS27155	COG0588	phosphoglycerate mutase activity
CTZ40_RS27205	COG0495	leucyl-tRNA aminoacylation
CTZ40_RS27215	COG1307	EDD domain protein, DegV family
CTZ40_RS27220	COG1555	photosystem II stabilization
CTZ40_RS27220	COG1596	polysaccharide export
CTZ40_RS27225	COG1234	tRNA 3'-trailer cleavage
CTZ40_RS27230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTZ40_RS27235	COG1959	2 iron, 2 sulfur cluster binding
CTZ40_RS27265	COG0268	Binds directly to 16S ribosomal RNA
CTZ40_RS27270	COG0481	GTPase activity
CTZ40_RS27280	COG1022	Amp-dependent synthetase and ligase
CTZ40_RS27285	COG3437	response regulator, receiver
CTZ40_RS27320	COG1420	regulation of RNA biosynthetic process
CTZ40_RS27325	COG0484	heat shock protein binding
CTZ40_RS27355	COG0537	adenosine 5'-monophosphoramidase activity
CTZ40_RS27360	COG1234	tRNA 3'-trailer cleavage
CTZ40_RS27370	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ40_RS27385	COG1486	melibiose metabolic process
CTZ40_RS27390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ40_RS27400	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CTZ40_RS27410	COG2814	Major facilitator Superfamily
CTZ40_RS27450	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS27455	COG0492	ferredoxin-NADP+ reductase activity
CTZ40_RS27470	COG0475	glutathione-regulated potassium exporter activity
CTZ40_RS27475	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTZ40_RS27485	COG2723	6-phospho-beta-galactosidase activity
CTZ40_RS27500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTZ40_RS27510	COG1381	Involved in DNA repair and RecF pathway recombination
CTZ40_RS27515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTZ40_RS27525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTZ40_RS27530	COG1121	(ABC) transporter
CTZ40_RS27540	COG0423	glycine-tRNA ligase activity
CTZ40_RS27555	COG2197	response regulator
CTZ40_RS27570	COG0667	Aldo Keto reductase
CTZ40_RS27575	COG0477	Major facilitator Superfamily
CTZ40_RS27600	COG0574	Belongs to the PEP-utilizing enzyme family
CTZ40_RS27600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTZ40_RS27610	COG2175	clavaminate synthase activity
CTZ40_RS27620	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS27625	COG1175	transmembrane transport
CTZ40_RS27635	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS27640	COG0789	Transcriptional regulator
CTZ40_RS27650	COG2814	Major facilitator Superfamily
CTZ40_RS27680	COG3485	protocatechuate 3,4-dioxygenase
CTZ40_RS27695	COG0531	amino acid
CTZ40_RS27715	COG2146	nitrite reductase [NAD(P)H] activity
CTZ40_RS27715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ40_RS27720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ40_RS27730	COG2197	response regulator
CTZ40_RS27745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTZ40_RS27775	COG2382	esterase
CTZ40_RS27815	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ40_RS27830	COG0243	molybdopterin cofactor binding
CTZ40_RS27840	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CTZ40_RS27855	COG0358	DNA primase activity
CTZ40_RS27860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CTZ40_RS27865	COG1070	Carbohydrate kinase
CTZ40_RS27895	COG1834	amidinotransferase
CTZ40_RS27910	COG3835	regulator
CTZ40_RS27915	COG2080	2 iron, 2 sulfur cluster binding
CTZ40_RS27915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTZ40_RS27920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTZ40_RS27930	COG1077	Cell shape determining protein MreB Mrl
CTZ40_RS27940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ40_RS27970	COG4981	capsule polysaccharide biosynthetic process
CTZ40_RS27975	COG0500	methyltransferase
CTZ40_RS28000	COG0477	Major facilitator Superfamily
CTZ40_RS28010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTZ40_RS28020	COG2130	NADP-dependent
CTZ40_RS28025	COG1764	response to oxidative stress
CTZ40_RS28040	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTZ40_RS28050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ40_RS28100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTZ40_RS28105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ40_RS28110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTZ40_RS28135	COG0789	Transcriptional regulator
CTZ40_RS28140	COG0667	Aldo Keto reductase
CTZ40_RS28155	COG2197	response regulator
CTZ40_RS28160	COG4585	Histidine kinase
CTZ40_RS28175	COG1309	transcriptional regulator
CTZ40_RS28180	COG0477	Major facilitator Superfamily
CTZ40_RS28195	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CTZ40_RS28250	COG0586	Pfam SNARE associated Golgi protein
CTZ40_RS28255	COG4585	Histidine kinase
CTZ40_RS28280	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ40_RS28305	COG2259	Doxx family
CTZ40_RS28315	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CTZ40_RS28330	COG1120	ATPase activity
CTZ40_RS28395	COG1072	(Pantothenic acid kinase))
CTZ40_RS28425	COG2259	Doxx family
CTZ40_RS28450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ40_RS28455	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTZ40_RS28455	COG3409	Peptidoglycan-binding domain 1 protein
CTZ40_RS28465	COG0456	acetyltransferase
CTZ40_RS28500	COG0477	Major facilitator Superfamily
CTZ40_RS28510	COG0667	Aldo Keto reductase
CTZ40_RS28525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ40_RS28550	COG2124	cytochrome p450
CTZ40_RS28555	COG0183	Belongs to the thiolase family
CTZ40_RS28565	COG2318	DinB family
CTZ40_RS28590	COG3845	ABC transporter
CTZ40_RS28605	COG1657	PFAM Prenyltransferase squalene oxidase
CTZ40_RS28625	COG0515	serine threonine protein kinase
CTZ40_RS28635	COG1132	(ABC) transporter
CTZ40_RS28640	COG1132	(ABC) transporter
CTZ40_RS28645	COG2197	response regulator
CTZ40_RS28650	COG1309	transcriptional regulator
CTZ40_RS28690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ40_RS28700	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTZ40_RS28710	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS28715	COG0183	Belongs to the thiolase family
CTZ40_RS28725	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS28730	COG0509	glycine decarboxylation via glycine cleavage system
CTZ40_RS28735	COG2197	response regulator
CTZ40_RS28770	COG4585	Histidine kinase
CTZ40_RS28775	COG2030	dehydratase
CTZ40_RS28785	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS28800	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTZ40_RS28815	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CTZ40_RS28820	COG0800	Aldolase
CTZ40_RS28825	COG3022	response to hydroperoxide
CTZ40_RS28830	COG0557	exoribonuclease II activity
CTZ40_RS28840	COG0789	Transcriptional regulator
CTZ40_RS28850	COG1957	nucleoside hydrolase
CTZ40_RS28855	COG3629	intracellular signal transduction
CTZ40_RS28855	COG3903	Transcriptional regulator
CTZ40_RS29190	COG0776	regulation of translation
CTZ40_RS29320	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ40_RS29325	COG0535	radical SAM domain protein
CTZ40_RS29355	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CTZ40_RS29380	COG3540	Alkaline phosphatase
CTZ40_RS29385	COG2814	Major facilitator Superfamily
CTZ40_RS29390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ40_RS29400	COG1834	amidinotransferase
CTZ40_RS29425	COG0672	)-iron permease
CTZ40_RS29430	COG2837	iron assimilation
CTZ40_RS29440	COG1120	ATPase activity
CTZ40_RS29445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS29450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTZ40_RS29505	COG1175	transmembrane transport
CTZ40_RS29510	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS29540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ40_RS29545	COG1994	Peptidase M50
CTZ40_RS29575	COG1687	branched-chain amino acid
CTZ40_RS29580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CTZ40_RS29585	COG0477	Major facilitator Superfamily
CTZ40_RS29600	COG2814	Major facilitator Superfamily
CTZ40_RS29610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTZ40_RS29610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ40_RS29615	COG2132	Multicopper oxidase
CTZ40_RS29640	COG0174	glutamine synthetase
CTZ40_RS29645	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTZ40_RS29655	COG1609	Transcriptional regulator
CTZ40_RS29660	COG0366	Alpha amylase catalytic
CTZ40_RS29665	COG2182	Extracellular solute-binding protein
CTZ40_RS29670	COG1175	transmembrane transport
CTZ40_RS29675	COG3833	ABC-type maltose transport systems, permease component
CTZ40_RS29680	COG0366	Alpha amylase catalytic
CTZ40_RS29705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ40_RS29760	COG1309	transcriptional regulator
CTZ40_RS29785	COG2197	response regulator
CTZ40_RS29790	COG4585	Histidine kinase
CTZ40_RS29805	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS29820	COG3591	Belongs to the peptidase S1B family
CTZ40_RS29825	COG0673	inositol 2-dehydrogenase activity
CTZ40_RS29840	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS29845	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS29850	COG2205	protein histidine kinase activity
CTZ40_RS29895	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ40_RS29900	COG0321	lipoyl(octanoyl) transferase activity
CTZ40_RS29915	COG1090	epimerase
CTZ40_RS29940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CTZ40_RS29950	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ40_RS29955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ40_RS29960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CTZ40_RS29970	COG0438	transferase activity, transferring glycosyl groups
CTZ40_RS29995	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CTZ40_RS30010	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CTZ40_RS30010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CTZ40_RS30015	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CTZ40_RS30035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ40_RS30040	COG1132	(ABC) transporter
CTZ40_RS30045	COG2226	methyltransferase
CTZ40_RS30065	COG4585	Histidine kinase
CTZ40_RS30070	COG2197	response regulator
CTZ40_RS30075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ40_RS30085	COG2161	toxin-antitoxin pair type II binding
CTZ40_RS30090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTZ40_RS30110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ40_RS30120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTZ40_RS30125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ40_RS30135	COG1376	ErfK ybiS ycfS ynhG family protein
CTZ40_RS30145	COG1845	cytochrome c oxidase, subunit III
CTZ40_RS30150	COG2010	Cytochrome c
CTZ40_RS30155	COG0723	plastoquinol--plastocyanin reductase activity
CTZ40_RS30160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CTZ40_RS30165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTZ40_RS30170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTZ40_RS30180	COG0705	Rhomboid family
CTZ40_RS30200	COG3883	PFAM NLP P60 protein
CTZ40_RS30200	COG0791	NLP P60 protein
CTZ40_RS30215	COG0438	transferase activity, transferring glycosyl groups
CTZ40_RS30235	COG0003	Pfam Anion-transporting ATPase
CTZ40_RS30245	COG1940	carbohydrate kinase activity
CTZ40_RS30280	COG2197	response regulator
CTZ40_RS30285	COG0205	6-phosphofructokinase activity
CTZ40_RS30290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTZ40_RS30300	COG2267	carboxylic ester hydrolase activity
CTZ40_RS30305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ40_RS30310	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CTZ40_RS30320	COG2193	ferroxidase activity
CTZ40_RS30325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CTZ40_RS30335	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CTZ40_RS30340	COG0515	serine threonine protein kinase
CTZ40_RS30340	COG2815	serine threonine protein kinase
CTZ40_RS30345	COG2022	thiamine diphosphate biosynthetic process
CTZ40_RS30355	COG2022	thiamine diphosphate biosynthetic process
CTZ40_RS30355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ40_RS30370	COG0352	thiamine-phosphate diphosphorylase activity
CTZ40_RS30385	COG1233	COG1233 Phytoene dehydrogenase and related
CTZ40_RS30395	COG1309	transcriptional regulator
CTZ40_RS30415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ40_RS30435	COG0714	Associated with various cellular activities
CTZ40_RS30445	COG0275	rRNA processing
CTZ40_RS30455	COG0768	penicillin binding
CTZ40_RS30460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTZ40_RS30470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTZ40_RS30475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CTZ40_RS30485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CTZ40_RS30490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTZ40_RS30515	COG1799	cell septum assembly
CTZ40_RS30525	COG3599	regulation of cell shape
CTZ40_RS30530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTZ40_RS30545	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CTZ40_RS30600	COG0587	DNA-directed DNA polymerase activity
CTZ40_RS30605	COG1432	Conserved Protein
CTZ40_RS30625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTZ40_RS30640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTZ40_RS30645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CTZ40_RS30650	COG0131	Imidazoleglycerol-phosphate dehydratase
CTZ40_RS30655	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTZ40_RS30660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CTZ40_RS30665	COG0251	oxidation-reduction process
CTZ40_RS30670	COG0107	imidazoleglycerol-phosphate synthase activity
CTZ40_RS30685	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTZ40_RS30690	COG1053	succinate dehydrogenase
CTZ40_RS30700	COG0583	DNA-binding transcription factor activity
CTZ40_RS30705	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CTZ40_RS30715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CTZ40_RS30735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTZ40_RS30760	COG0134	indole-3-glycerol-phosphate synthase activity
CTZ40_RS30770	COG0133	tryptophan synthase activity
CTZ40_RS30775	COG0159	tryptophan synthase activity
CTZ40_RS30785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CTZ40_RS30790	COG2301	Belongs to the HpcH HpaI aldolase family
CTZ40_RS30795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ40_RS30820	COG1609	Transcriptional regulator
CTZ40_RS30830	COG0069	glutamate synthase activity
CTZ40_RS30830	COG0067	glutamate synthase
CTZ40_RS30830	COG0070	glutamate synthase
CTZ40_RS30840	COG1846	Transcriptional regulator
CTZ40_RS30845	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS30850	COG3467	pyridoxamine 5'-phosphate
CTZ40_RS30865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ40_RS30870	COG0596	Alpha beta hydrolase
CTZ40_RS30905	COG0464	growth
CTZ40_RS30925	COG2197	response regulator
CTZ40_RS30935	COG1470	cell adhesion involved in biofilm formation
CTZ40_RS30935	COG0366	Alpha amylase catalytic
CTZ40_RS30965	COG0737	Belongs to the 5'-nucleotidase family
CTZ40_RS31025	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ40_RS31060	COG1643	Atp-dependent helicase
CTZ40_RS31065	COG2226	methyltransferase
CTZ40_RS31090	COG0237	dephospho-CoA kinase activity
CTZ40_RS31115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CTZ40_RS31120	COG4279	zinc finger
CTZ40_RS31165	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ40_RS31170	COG0556	nucleotide-excision repair
CTZ40_RS31215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ40_RS31230	COG1063	alcohol dehydrogenase
CTZ40_RS31235	COG2814	Major facilitator Superfamily
CTZ40_RS31280	COG0322	excinuclease ABC activity
CTZ40_RS31285	COG1660	Displays ATPase and GTPase activities
CTZ40_RS31295	COG1481	regulation of sporulation
CTZ40_RS31300	COG0456	acetyltransferase
CTZ40_RS31300	COG0454	-acetyltransferase
CTZ40_RS31310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTZ40_RS31315	COG0126	phosphoglycerate kinase activity
CTZ40_RS31320	COG0149	triose-phosphate isomerase activity
CTZ40_RS31325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CTZ40_RS31335	COG0166	Belongs to the GPI family
CTZ40_RS31345	COG0363	glucosamine-6-phosphate deaminase activity
CTZ40_RS31360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTZ40_RS31365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTZ40_RS31370	COG0109	protoheme IX farnesyltransferase activity
CTZ40_RS31385	COG1612	heme a metabolic process
CTZ40_RS31410	COG0719	Fe-S assembly protein
CTZ40_RS31420	COG0396	ATPase activity
CTZ40_RS31425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTZ40_RS31430	COG0822	iron-sulfur transferase activity
CTZ40_RS31450	COG2076	Multidrug Resistance protein
CTZ40_RS31455	COG3226	Transcriptional regulator
CTZ40_RS31470	COG2171	N-acyltransferase activity
CTZ40_RS31485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ40_RS31515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ40_RS31550	COG2261	transglycosylase associated protein
CTZ40_RS31555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTZ40_RS31560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ40_RS31590	COG4585	Histidine kinase
CTZ40_RS31595	COG1414	Transcriptional regulator
CTZ40_RS31605	COG0456	acetyltransferase
CTZ40_RS31640	COG5285	phytanoyl-CoA dioxygenase
CTZ40_RS31645	COG1917	Cupin 2, conserved barrel domain protein
CTZ40_RS31650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ40_RS31665	COG0385	Bile acid
CTZ40_RS31690	COG1797	cobyrinic acid a,c-diamide synthase activity
CTZ40_RS31695	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CTZ40_RS31710	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CTZ40_RS31730	COG0235	Class ii aldolase
CTZ40_RS31755	COG0488	(ABC) transporter
CTZ40_RS31765	COG1024	Enoyl-CoA hydratase
CTZ40_RS31775	COG1302	Protein conserved in bacteria
CTZ40_RS31805	COG3387	PFAM Glycoside hydrolase 15-related
CTZ40_RS31820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CTZ40_RS31860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ40_RS31865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTZ40_RS31880	COG2261	transglycosylase associated protein
CTZ40_RS31885	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTZ40_RS31900	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS31905	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CTZ40_RS31910	COG2186	Transcriptional regulator
CTZ40_RS31915	COG2807	transmembrane transport
CTZ40_RS31930	COG0560	Phosphoserine phosphatase
CTZ40_RS31930	COG3830	Belongs to the UPF0237 family
CTZ40_RS31940	COG0842	Transport permease protein
CTZ40_RS31940	COG1716	ATPase activity
CTZ40_RS31940	COG1131	(ABC) transporter
CTZ40_RS31955	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CTZ40_RS31960	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS31965	COG4585	Histidine kinase
CTZ40_RS31970	COG2197	response regulator
CTZ40_RS31990	COG1119	ATPase activity
CTZ40_RS32015	COG1881	PFAM PEBP family protein
CTZ40_RS32025	COG2094	Belongs to the DNA glycosylase MPG family
CTZ40_RS32060	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CTZ40_RS32075	COG0647	UMP catabolic process
CTZ40_RS32090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS32095	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS32100	COG1120	ATPase activity
CTZ40_RS32120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTZ40_RS32140	COG0497	DNA recombination
CTZ40_RS32150	COG0438	transferase activity, transferring glycosyl groups
CTZ40_RS32180	COG3387	PFAM Glycoside hydrolase 15-related
CTZ40_RS32185	COG0504	CTP synthase activity
CTZ40_RS32190	COG0494	nUDIX hydrolase
CTZ40_RS32200	COG0686	Belongs to the AlaDH PNT family
CTZ40_RS32215	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTZ40_RS32220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CTZ40_RS32225	COG1187	pseudouridine synthase activity
CTZ40_RS32235	COG3541	Predicted nucleotidyltransferase
CTZ40_RS32260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CTZ40_RS32270	COG1160	GTP binding
CTZ40_RS32300	COG0411	ABC transporter
CTZ40_RS32335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ40_RS32395	COG0671	phosphoesterase, PA-phosphatase related
CTZ40_RS32405	COG0477	Major facilitator Superfamily
CTZ40_RS32410	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS32415	COG1799	cell septum assembly
CTZ40_RS32425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ40_RS32430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ40_RS32470	COG0326	Molecular chaperone. Has ATPase activity
CTZ40_RS32480	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS32490	COG0587	DNA-directed DNA polymerase activity
CTZ40_RS32495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ40_RS32525	COG0019	diaminopimelate decarboxylase activity
CTZ40_RS32555	COG1725	Transcriptional regulator
CTZ40_RS32565	COG1834	amidinotransferase
CTZ40_RS32585	COG0726	polysaccharide deacetylase
CTZ40_RS32590	COG1215	transferase activity, transferring glycosyl groups
CTZ40_RS32595	COG0463	Glycosyl transferase, family 2
CTZ40_RS32615	COG2815	serine threonine protein kinase
CTZ40_RS32615	COG0515	serine threonine protein kinase
CTZ40_RS32635	COG1595	DNA-templated transcription, initiation
CTZ40_RS32650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ40_RS32660	COG0477	Major facilitator Superfamily
CTZ40_RS32660	COG2814	Major facilitator Superfamily
CTZ40_RS32665	COG4195	phage-related replication protein
CTZ40_RS32670	COG2188	Transcriptional regulator
CTZ40_RS32675	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CTZ40_RS32680	COG2851	Citrate transporter
CTZ40_RS32740	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS32780	COG0477	Major facilitator Superfamily
CTZ40_RS32785	COG3876	Protein conserved in bacteria
CTZ40_RS32795	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS32805	COG0456	acetyltransferase
CTZ40_RS32805	COG1846	Transcriptional regulator
CTZ40_RS32810	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS32825	COG2149	membrane
CTZ40_RS32830	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CTZ40_RS32855	COG3573	Dehydrogenase
CTZ40_RS32890	COG3173	Aminoglycoside phosphotransferase
CTZ40_RS32895	COG5002	protein histidine kinase activity
CTZ40_RS32900	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS32925	COG2124	cytochrome p450
CTZ40_RS32930	COG0488	(ABC) transporter
CTZ40_RS33030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTZ40_RS33060	COG0667	Aldo Keto reductase
CTZ40_RS33065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ40_RS33075	COG0598	Magnesium transport protein CorA
CTZ40_RS33095	COG0215	cysteine-tRNA ligase activity
CTZ40_RS33120	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ40_RS33125	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS33135	COG1129	ABC transporter
CTZ40_RS33140	COG4211	Belongs to the binding-protein-dependent transport system permease family
CTZ40_RS33160	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS33165	COG2186	Transcriptional regulator
CTZ40_RS33170	COG0402	S-adenosylhomocysteine deaminase activity
CTZ40_RS33175	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CTZ40_RS33185	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CTZ40_RS33190	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CTZ40_RS33195	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CTZ40_RS33200	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTZ40_RS33205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CTZ40_RS33210	COG1414	Transcriptional regulator
CTZ40_RS33215	COG1410	methionine synthase
CTZ40_RS33215	COG0646	methionine synthase
CTZ40_RS33225	COG4166	transmembrane transport
CTZ40_RS33235	COG2197	response regulator
CTZ40_RS33245	COG1994	Peptidase M50
CTZ40_RS33245	COG0517	IMP dehydrogenase activity
CTZ40_RS33265	COG1222	aaa ATPase
CTZ40_RS33270	COG4122	O-methyltransferase activity
CTZ40_RS33285	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CTZ40_RS33290	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CTZ40_RS33295	COG1609	Transcriptional regulator
CTZ40_RS33305	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CTZ40_RS33320	COG2378	regulation of single-species biofilm formation
CTZ40_RS33340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CTZ40_RS33345	COG0805	protein transport
CTZ40_RS33355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ40_RS33370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTZ40_RS33375	COG4175	Glycine betaine
CTZ40_RS33375	COG0517	IMP dehydrogenase activity
CTZ40_RS33380	COG4176	ABC-type proline glycine betaine transport system permease component
CTZ40_RS33400	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CTZ40_RS33405	COG0531	amino acid
CTZ40_RS33410	COG2186	Transcriptional regulator
CTZ40_RS33415	COG0174	glutamine synthetase
CTZ40_RS33455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CTZ40_RS33465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CTZ40_RS33470	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CTZ40_RS33475	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CTZ40_RS33480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ40_RS33485	COG5002	protein histidine kinase activity
CTZ40_RS33490	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CTZ40_RS33495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ40_RS33495	COG0072	phenylalanine-tRNA ligase activity
CTZ40_RS33525	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ40_RS33535	COG0697	spore germination
CTZ40_RS33550	COG1486	melibiose metabolic process
CTZ40_RS33555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ40_RS33560	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS33565	COG1175	transmembrane transport
CTZ40_RS33570	COG2182	Extracellular solute-binding protein
CTZ40_RS33605	COG1595	DNA-templated transcription, initiation
CTZ40_RS33610	COG1660	Displays ATPase and GTPase activities
CTZ40_RS33635	COG2838	Isocitrate dehydrogenase
CTZ40_RS33650	COG4585	Histidine kinase
CTZ40_RS33655	COG2197	response regulator
CTZ40_RS33690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ40_RS33705	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CTZ40_RS33710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CTZ40_RS33715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CTZ40_RS33720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ40_RS33725	COG1438	arginine binding
CTZ40_RS33730	COG1228	amidohydrolase
CTZ40_RS33785	COG0137	argininosuccinate synthase activity
CTZ40_RS33790	COG0165	Argininosuccinate lyase
CTZ40_RS33800	COG0477	Major facilitator Superfamily
CTZ40_RS33805	COG0737	Belongs to the 5'-nucleotidase family
CTZ40_RS33815	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ40_RS33840	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ40_RS33845	COG2011	ABC-type metal ion transport system permease component
CTZ40_RS33850	COG1464	Belongs to the NlpA lipoprotein family
CTZ40_RS33865	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CTZ40_RS33870	COG1648	precorrin-2 dehydrogenase activity
CTZ40_RS33870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTZ40_RS33875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ40_RS33940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTZ40_RS33995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ40_RS34010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CTZ40_RS34040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTZ40_RS34045	COG1560	Kdo2-lipid A biosynthetic process
CTZ40_RS34050	COG0438	transferase activity, transferring glycosyl groups
CTZ40_RS34065	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CTZ40_RS34070	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CTZ40_RS34075	COG0217	transcriptional regulatory protein
CTZ40_RS34080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CTZ40_RS34085	COG0632	four-way junction helicase activity
CTZ40_RS34090	COG2255	four-way junction helicase activity
CTZ40_RS34100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTZ40_RS34105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTZ40_RS34110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CTZ40_RS34115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ40_RS34120	COG1196	nuclear chromosome segregation
CTZ40_RS34125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTZ40_RS34135	COG0124	histidyl-tRNA synthetase
CTZ40_RS34155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CTZ40_RS34175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CTZ40_RS34180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTZ40_RS34195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CTZ40_RS34200	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CTZ40_RS34205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CTZ40_RS34210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CTZ40_RS34215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CTZ40_RS34230	COG0006	proline dipeptidase activity
CTZ40_RS34235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CTZ40_RS34240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CTZ40_RS34250	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CTZ40_RS34255	COG0540	Belongs to the ATCase OTCase family
CTZ40_RS34260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CTZ40_RS34270	COG0505	Belongs to the CarA family
CTZ40_RS34275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CTZ40_RS34280	COG0167	dihydroorotate dehydrogenase activity
CTZ40_RS34285	COG0284	orotidine-5'-phosphate decarboxylase activity
CTZ40_RS34310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CTZ40_RS34345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CTZ40_RS34355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTZ40_RS34360	COG2390	Transcriptional regulator
CTZ40_RS34400	COG0531	amino acid
CTZ40_RS34425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ40_RS34445	COG2233	PERMEase
CTZ40_RS34455	COG0738	Major facilitator superfamily
CTZ40_RS34460	COG1940	carbohydrate kinase activity
CTZ40_RS34460	COG1846	Transcriptional regulator
CTZ40_RS34465	COG0702	epimerase
CTZ40_RS34480	COG3201	nicotinamide mononucleotide transporter
CTZ40_RS34485	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTZ40_RS34485	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTZ40_RS34490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CTZ40_RS34495	COG0140	phosphoribosyl-ATP diphosphatase activity
CTZ40_RS34500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTZ40_RS34555	COG0671	phosphoesterase, PA-phosphatase related
CTZ40_RS34580	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ40_RS34625	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CTZ40_RS34635	COG1191	sigma factor activity
CTZ40_RS34660	COG2318	DinB family
CTZ40_RS34665	COG4249	Peptidase C14 caspase catalytic subunit p20
CTZ40_RS34665	COG2319	Wd-40 repeat
CTZ40_RS34680	COG3973	AAA domain
CTZ40_RS34715	COG3345	alpha-galactosidase
CTZ40_RS34725	COG1175	transmembrane transport
CTZ40_RS34730	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS34750	COG0644	oxidoreductase
CTZ40_RS34755	COG4585	Histidine kinase
CTZ40_RS34760	COG2197	response regulator
CTZ40_RS34780	COG1940	carbohydrate kinase activity
CTZ40_RS34830	COG1349	DNA-binding transcription factor activity
CTZ40_RS34840	COG0464	growth
CTZ40_RS34880	COG0463	Glycosyl transferase, family 2
CTZ40_RS34885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ40_RS34945	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS34990	COG0640	Transcriptional regulator
CTZ40_RS35010	COG2111	Na H antiporter
CTZ40_RS35015	COG1006	Multisubunit Na H antiporter MnhC subunit
CTZ40_RS35020	COG1007	ATP synthesis coupled electron transport
CTZ40_RS35030	COG1461	Dihydroxyacetone kinase
CTZ40_RS35035	COG2376	Dihydroxyacetone kinase
CTZ40_RS35075	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CTZ40_RS35090	COG0596	Alpha beta hydrolase
CTZ40_RS35110	COG1309	transcriptional regulator
CTZ40_RS35120	COG1414	Transcriptional regulator
CTZ40_RS35125	COG3386	PFAM SMP-30 Gluconolaconase
CTZ40_RS35140	COG4214	carbohydrate transport
CTZ40_RS35180	COG1366	Belongs to the anti-sigma-factor antagonist family
CTZ40_RS35180	COG2172	sigma factor antagonist activity
CTZ40_RS35180	COG2208	phosphoserine phosphatase activity
CTZ40_RS35195	COG2318	DinB family
CTZ40_RS35205	COG0367	asparagine synthase
CTZ40_RS35230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTZ40_RS35235	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS35240	COG0515	serine threonine protein kinase
CTZ40_RS35255	COG2070	2-Nitropropane dioxygenase
CTZ40_RS35265	COG2366	antibiotic biosynthetic process
CTZ40_RS35270	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS35315	COG1605	Chorismate mutase
CTZ40_RS35370	COG4221	oxidoreductase activity
CTZ40_RS35405	COG2124	cytochrome p450
CTZ40_RS35410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ40_RS35455	COG0438	transferase activity, transferring glycosyl groups
CTZ40_RS35460	COG0438	transferase activity, transferring glycosyl groups
CTZ40_RS35475	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CTZ40_RS35485	COG1984	allophanate hydrolase subunit 2
CTZ40_RS35490	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CTZ40_RS35495	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CTZ40_RS35515	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CTZ40_RS35560	COG2146	nitrite reductase [NAD(P)H] activity
CTZ40_RS35615	COG0442	prolyl-tRNA aminoacylation
CTZ40_RS35620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTZ40_RS35625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CTZ40_RS35630	COG3447	MASE1 domain protein
CTZ40_RS35630	COG5001	Diguanylate cyclase
CTZ40_RS35630	COG5002	protein histidine kinase activity
CTZ40_RS35635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTZ40_RS35645	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CTZ40_RS35660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ40_RS35670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTZ40_RS35705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTZ40_RS35725	COG1716	ATPase activity
CTZ40_RS35745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ40_RS35755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CTZ40_RS35755	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CTZ40_RS35780	COG0384	phenazine biosynthesis protein PhzF
CTZ40_RS35790	COG0789	Transcriptional regulator
CTZ40_RS35800	COG1695	Transcriptional regulator
CTZ40_RS35815	COG0697	spore germination
CTZ40_RS35835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTZ40_RS35840	COG0697	spore germination
CTZ40_RS35860	COG0825	malonyl-CoA metabolic process
CTZ40_RS35860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CTZ40_RS35865	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ40_RS35885	COG0823	Involved in the tonB-independent uptake of proteins
CTZ40_RS35885	COG4946	Tricorn protease homolog
CTZ40_RS35885	COG1506	peptidase
CTZ40_RS35940	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS35960	COG0154	amidase activity
CTZ40_RS35985	COG0667	Aldo Keto reductase
CTZ40_RS35990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CTZ40_RS36025	COG1132	(ABC) transporter
CTZ40_RS36035	COG0640	Transcriptional regulator
CTZ40_RS36040	COG1252	NADH dehydrogenase
CTZ40_RS36050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CTZ40_RS36065	COG0386	Belongs to the glutathione peroxidase family
CTZ40_RS36075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTZ40_RS36130	COG2267	carboxylic ester hydrolase activity
CTZ40_RS36135	COG0531	amino acid
CTZ40_RS36185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ40_RS36190	COG0019	diaminopimelate decarboxylase activity
CTZ40_RS36195	COG0531	amino acid
CTZ40_RS36210	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CTZ40_RS36215	COG2205	protein histidine kinase activity
CTZ40_RS36255	COG4733	cellulase activity
CTZ40_RS36260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ40_RS36320	COG0583	DNA-binding transcription factor activity
CTZ40_RS36340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTZ40_RS36350	COG3795	YCII-related domain
CTZ40_RS36355	COG4941	Belongs to the sigma-70 factor family
CTZ40_RS36370	COG1595	DNA-templated transcription, initiation
CTZ40_RS36420	COG0438	transferase activity, transferring glycosyl groups
CTZ40_RS36425	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS36430	COG2205	protein histidine kinase activity
CTZ40_RS36450	COG1968	undecaprenyl-diphosphatase activity
CTZ40_RS36465	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CTZ40_RS36515	COG1793	dna ligase
CTZ40_RS36515	COG3285	dna ligase
CTZ40_RS36525	COG1366	Belongs to the anti-sigma-factor antagonist family
CTZ40_RS36530	COG0248	Ppx GppA phosphatase
CTZ40_RS36550	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS36555	COG0300	oxidoreductase activity
CTZ40_RS36585	COG0110	maltose O-acetyltransferase activity
CTZ40_RS36595	COG1470	cell adhesion involved in biofilm formation
CTZ40_RS36600	COG2124	cytochrome p450
CTZ40_RS36605	COG1309	transcriptional regulator
CTZ40_RS36640	COG1832	CoA-binding protein
CTZ40_RS36645	COG1739	Uncharacterized protein family UPF0029
CTZ40_RS36675	COG1335	isochorismatase
CTZ40_RS36680	COG1982	Orn Lys Arg decarboxylase major
CTZ40_RS36685	COG0243	molybdopterin cofactor binding
CTZ40_RS36685	COG3383	formate dehydrogenase (NAD+) activity
CTZ40_RS36690	COG0437	4 iron, 4 sulfur cluster binding
CTZ40_RS36705	COG1846	Transcriptional regulator
CTZ40_RS36715	COG1597	lipid kinase activity
CTZ40_RS36725	COG2706	6-phosphogluconolactonase activity
CTZ40_RS36735	COG0823	Involved in the tonB-independent uptake of proteins
CTZ40_RS36740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTZ40_RS36745	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ40_RS36790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS36800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS36825	COG0535	radical SAM domain protein
CTZ40_RS36835	COG1140	nitrate reductase beta subunit
CTZ40_RS36840	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CTZ40_RS36845	COG2181	nitrate reductase activity
CTZ40_RS36855	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CTZ40_RS36865	COG1140	nitrate reductase beta subunit
CTZ40_RS36910	COG1882	Formate acetyltransferase
CTZ40_RS36915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CTZ40_RS36930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ40_RS36930	COG2146	nitrite reductase [NAD(P)H] activity
CTZ40_RS36950	COG0667	Aldo Keto reductase
CTZ40_RS37020	COG1113	amino acid transport
CTZ40_RS37030	COG1132	(ABC) transporter
CTZ40_RS37045	COG0420	3'-5' exonuclease activity
CTZ40_RS37050	COG0419	ATPase involved in DNA repair
CTZ40_RS37055	COG1522	sequence-specific DNA binding
CTZ40_RS37065	COG2226	methyltransferase
CTZ40_RS37105	COG1595	DNA-templated transcription, initiation
CTZ40_RS37110	COG2188	Transcriptional regulator
CTZ40_RS37125	COG1940	carbohydrate kinase activity
CTZ40_RS37140	COG3663	DNA glycosylase
CTZ40_RS37145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTZ40_RS37160	COG0583	DNA-binding transcription factor activity
CTZ40_RS37200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ40_RS37205	COG0577	efflux transmembrane transporter activity
CTZ40_RS37210	COG0577	efflux transmembrane transporter activity
CTZ40_RS37210	COG1136	(ABC) transporter
CTZ40_RS37230	COG2226	methyltransferase
CTZ40_RS37235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CTZ40_RS37240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CTZ40_RS37245	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CTZ40_RS37290	COG0740	serine-type endopeptidase activity
CTZ40_RS37320	COG0831	urea catabolic process
CTZ40_RS37325	COG0832	Belongs to the urease beta subunit family
CTZ40_RS37330	COG0804	urea catabolic process
CTZ40_RS37335	COG0830	nickel cation binding
CTZ40_RS37340	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CTZ40_RS37345	COG0829	nickel cation binding
CTZ40_RS37355	COG1309	transcriptional regulator
CTZ40_RS37360	COG0154	amidase activity
CTZ40_RS37365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS37380	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS37385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS37435	COG0604	alcohol dehydrogenase
CTZ40_RS37455	COG0431	NADPH-dependent FMN reductase
CTZ40_RS37480	COG1454	alcohol dehydrogenase
CTZ40_RS37485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTZ40_RS37490	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS37495	COG3629	intracellular signal transduction
CTZ40_RS37495	COG3903	Transcriptional regulator
CTZ40_RS37505	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CTZ40_RS37555	COG0702	epimerase
CTZ40_RS37570	COG1473	amidohydrolase
CTZ40_RS37575	COG3135	benzoate transporter
CTZ40_RS37590	COG2423	ornithine cyclodeaminase activity
CTZ40_RS37595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ40_RS37600	COG3629	intracellular signal transduction
CTZ40_RS37600	COG3903	Transcriptional regulator
CTZ40_RS37625	COG1063	alcohol dehydrogenase
CTZ40_RS37645	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CTZ40_RS37660	COG1609	Transcriptional regulator
CTZ40_RS37665	COG2222	sugar isomerase
CTZ40_RS37675	COG1653	transport
CTZ40_RS37680	COG1175	transmembrane transport
CTZ40_RS37685	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS37690	COG1793	dna ligase
CTZ40_RS37695	COG1957	nucleoside hydrolase
CTZ40_RS37700	COG0477	Major facilitator Superfamily
CTZ40_RS37705	COG0596	Alpha beta hydrolase
CTZ40_RS37740	COG0205	6-phosphofructokinase activity
CTZ40_RS37745	COG3442	glutamine amidotransferase
CTZ40_RS37755	COG0242	peptide deformylase activity
CTZ40_RS37765	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS37790	COG0505	Belongs to the CarA family
CTZ40_RS37795	COG3960	tartronate-semialdehyde synthase activity
CTZ40_RS37800	COG3622	Belongs to the hyi family
CTZ40_RS37805	COG2084	Dehydrogenase
CTZ40_RS37820	COG1131	(ABC) transporter
CTZ40_RS37870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS37885	COG2378	regulation of single-species biofilm formation
CTZ40_RS37915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CTZ40_RS37925	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CTZ40_RS37945	COG1191	sigma factor activity
CTZ40_RS37980	COG2124	cytochrome p450
CTZ40_RS38005	COG1653	transport
CTZ40_RS38020	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS38055	COG0395	ABC-type sugar transport system, permease component
CTZ40_RS38090	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS38105	COG3284	Transcriptional regulator
CTZ40_RS38120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS38155	COG2197	response regulator
CTZ40_RS38185	COG1657	PFAM Prenyltransferase squalene oxidase
CTZ40_RS38205	COG0142	geranyltranstransferase activity
CTZ40_RS38210	COG1482	cell wall glycoprotein biosynthetic process
CTZ40_RS38260	COG1012	belongs to the aldehyde dehydrogenase family
CTZ40_RS38265	COG2197	response regulator
CTZ40_RS38270	COG4977	sequence-specific DNA binding
CTZ40_RS38275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CTZ40_RS38300	COG1063	alcohol dehydrogenase
CTZ40_RS38305	COG2207	Transcriptional regulator
CTZ40_RS38315	COG0328	RNA-DNA hybrid ribonuclease activity
CTZ40_RS38320	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CTZ40_RS38345	COG1116	anion transmembrane transporter activity
CTZ40_RS38380	COG1316	TRANSCRIPTIONal
CTZ40_RS38415	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS38425	COG4585	Histidine kinase
CTZ40_RS38430	COG2197	response regulator
CTZ40_RS38440	COG0438	transferase activity, transferring glycosyl groups
CTZ40_RS38540	COG2124	cytochrome p450
CTZ40_RS38555	COG0596	Alpha beta hydrolase
CTZ40_RS38620	COG0671	phosphoesterase, PA-phosphatase related
CTZ40_RS38650	COG4221	oxidoreductase activity
CTZ40_RS38665	COG0110	maltose O-acetyltransferase activity
CTZ40_RS38690	COG0367	asparagine synthase
CTZ40_RS38705	COG2124	cytochrome p450
CTZ40_RS38735	COG0583	DNA-binding transcription factor activity
CTZ40_RS38760	COG3321	synthase
CTZ40_RS38760	COG0604	alcohol dehydrogenase
CTZ40_RS38760	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS38775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CTZ40_RS38800	COG2732	(Barnase) inhibitor
CTZ40_RS38880	COG0494	nUDIX hydrolase
CTZ40_RS38930	COG0596	Alpha beta hydrolase
CTZ40_RS38935	COG4221	oxidoreductase activity
CTZ40_RS38960	COG0574	Belongs to the PEP-utilizing enzyme family
CTZ40_RS38960	COG3848	Pyruvate phosphate dikinase
CTZ40_RS38995	COG1228	amidohydrolase
CTZ40_RS39000	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CTZ40_RS39025	COG4106	trans-aconitate 2-methyltransferase activity
CTZ40_RS39065	COG2197	response regulator
CTZ40_RS39115	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CTZ40_RS39130	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ40_RS39140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTZ40_RS39170	COG2770	Histidine kinase
CTZ40_RS39170	COG2208	phosphoserine phosphatase activity
CTZ40_RS39180	COG2172	sigma factor antagonist activity
CTZ40_RS39185	COG1366	Belongs to the anti-sigma-factor antagonist family
CTZ40_RS39190	COG1366	Belongs to the anti-sigma-factor antagonist family
CTZ40_RS39195	COG1191	sigma factor activity
CTZ40_RS39220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ40_RS39235	COG2175	clavaminate synthase activity
CTZ40_RS39250	COG3629	intracellular signal transduction
CTZ40_RS39250	COG3903	Transcriptional regulator
CTZ40_RS39265	COG0583	DNA-binding transcription factor activity
CTZ40_RS39335	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS39340	COG2259	Doxx family
CTZ40_RS39410	COG0154	amidase activity
CTZ40_RS39415	COG0300	oxidoreductase activity
CTZ40_RS39425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTZ40_RS39465	COG0477	Major facilitator Superfamily
CTZ40_RS39475	COG2271	Major facilitator Superfamily
CTZ40_RS39485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CTZ40_RS39490	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS39495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ40_RS39515	COG0346	lactoylglutathione lyase activity
CTZ40_RS39540	COG0366	Alpha amylase catalytic
CTZ40_RS39555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ40_RS39565	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS39570	COG2205	protein histidine kinase activity
CTZ40_RS39575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS39590	COG1131	(ABC) transporter
CTZ40_RS39610	COG1191	sigma factor activity
CTZ40_RS39620	COG0596	Alpha beta hydrolase
CTZ40_RS39625	COG1309	transcriptional regulator
CTZ40_RS39630	COG0640	Transcriptional regulator
CTZ40_RS39635	COG0673	inositol 2-dehydrogenase activity
CTZ40_RS39655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ40_RS39665	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS39675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ40_RS39680	COG2124	cytochrome p450
CTZ40_RS39685	COG2124	cytochrome p450
CTZ40_RS39745	COG0657	acetylesterase activity
CTZ40_RS39750	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS39775	COG1960	acyl-CoA dehydrogenase activity
CTZ40_RS39785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CTZ40_RS39800	COG0585	pseudouridine synthase activity
CTZ40_RS39840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS39845	COG3251	PFAM MbtH domain protein
CTZ40_RS39865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ40_RS39870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS39880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS39890	COG0789	Transcriptional regulator
CTZ40_RS39910	COG0745	RESPONSE REGULATOR receiver
CTZ40_RS39915	COG2205	protein histidine kinase activity
CTZ40_RS39925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTZ40_RS39935	COG1181	Belongs to the D-alanine--D-alanine ligase family
CTZ40_RS39940	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CTZ40_RS39975	COG2770	Histidine kinase
CTZ40_RS39975	COG2208	phosphoserine phosphatase activity
CTZ40_RS39980	COG0596	Alpha beta hydrolase
CTZ40_RS39985	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS40000	COG1301	dicarboxylic acid transport
CTZ40_RS40005	COG0473	3-isopropylmalate dehydrogenase activity
CTZ40_RS40010	COG0583	DNA-binding transcription factor activity
CTZ40_RS40060	COG0477	Major facilitator Superfamily
CTZ40_RS40105	COG2205	protein histidine kinase activity
CTZ40_RS40140	COG0583	DNA-binding transcription factor activity
CTZ40_RS40145	COG0384	phenazine biosynthesis protein PhzF
CTZ40_RS40220	COG0137	argininosuccinate synthase activity
CTZ40_RS40250	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS40270	COG0456	acetyltransferase
CTZ40_RS40270	COG1214	PFAM Peptidase M22, glycoprotease
CTZ40_RS40290	COG0596	Alpha beta hydrolase
CTZ40_RS40300	COG2814	Major facilitator Superfamily
CTZ40_RS40310	COG0697	spore germination
CTZ40_RS40375	COG1254	Belongs to the acylphosphatase family
CTZ40_RS40390	COG0604	alcohol dehydrogenase
CTZ40_RS40395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ40_RS40440	COG1309	transcriptional regulator
CTZ40_RS40450	COG0251	oxidation-reduction process
CTZ40_RS40460	COG2022	thiamine diphosphate biosynthetic process
CTZ40_RS40460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ40_RS40515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ40_RS40525	COG0300	oxidoreductase activity
CTZ40_RS40530	COG0300	oxidoreductase activity
CTZ40_RS40540	COG2409	Drug exporters of the RND superfamily
CTZ40_RS40545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTZ40_RS40550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ40_RS40555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTZ40_RS40635	COG0513	Belongs to the DEAD box helicase family
CTZ40_RS40640	COG1278	Cold shock
CTZ40_RS40700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CTZ40_RS40720	COG0300	oxidoreductase activity
CTZ40_RS40725	COG0583	DNA-binding transcription factor activity
CTZ40_RS40740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CTZ40_RS40745	COG0443	Heat shock 70 kDa protein
CTZ40_RS40750	COG0484	heat shock protein binding
CTZ40_RS40825	COG1733	regulation of RNA biosynthetic process
CTZ40_RS40845	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CTZ40_RS40860	COG4106	trans-aconitate 2-methyltransferase activity
CTZ40_RS40885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ40_RS40890	COG2197	response regulator
CTZ40_RS40900	COG2318	DinB family
CTZ40_RS40910	COG2175	clavaminate synthase activity
CTZ40_RS40920	COG3479	Phenolic acid decarboxylase
CTZ40_RS40935	COG2264	protein methyltransferase activity
CTZ40_RS40965	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ40_RS41070	COG1074	ATP-dependent DNA helicase activity
CTZ40_RS41115	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CTZ40_RS41165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ40_RS41360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CTZ40_RS41425	COG1309	transcriptional regulator
CTZ40_RS41570	COG2188	Transcriptional regulator
CTZ40_RS41680	COG1660	Displays ATPase and GTPase activities
CTZ40_RS41805	COG1192	Involved in chromosome partitioning
CTZ40_RS41810	COG1475	DNA binding
CTZ40_RS41815	COG2801	Transposase and inactivated derivatives
CTZ40_RS41815	COG3415	Transposase
CTZ40_RS41835	COG4974	Belongs to the 'phage' integrase family
CTZ40_RS42050	COG1185	polyribonucleotide nucleotidyltransferase activity
CTZ40_RS42175	COG4221	oxidoreductase activity
CTZ40_RS42255	COG2234	aminopeptidase activity
CTZ40_RS42310	COG2353	YceI-like domain
CTZ40_RS42315	COG0583	DNA-binding transcription factor activity
CTZ40_RS42325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ40_RS42335	COG0431	NADPH-dependent FMN reductase