locus-tag	class	description
SRIM_RS00060	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS00090	COG2890	protein-(glutamine-N5) methyltransferase activity
SRIM_RS00105	COG3479	Phenolic acid decarboxylase
SRIM_RS00115	COG2175	clavaminate synthase activity
SRIM_RS00125	COG2318	DinB family
SRIM_RS00135	COG2197	response regulator
SRIM_RS00140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRIM_RS00165	COG4106	trans-aconitate 2-methyltransferase activity
SRIM_RS00180	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SRIM_RS00205	COG1733	regulation of RNA biosynthetic process
SRIM_RS00290	COG0484	heat shock protein binding
SRIM_RS00295	COG0443	Heat shock 70 kDa protein
SRIM_RS00300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SRIM_RS00320	COG0583	DNA-binding transcription factor activity
SRIM_RS00325	COG0300	oxidoreductase activity
SRIM_RS00345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SRIM_RS00405	COG1278	Cold shock
SRIM_RS00410	COG0513	Belongs to the DEAD box helicase family
SRIM_RS00485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIM_RS00490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIM_RS00495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIM_RS00500	COG2409	Drug exporters of the RND superfamily
SRIM_RS00510	COG0300	oxidoreductase activity
SRIM_RS00515	COG0300	oxidoreductase activity
SRIM_RS00525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS00580	COG2022	thiamine diphosphate biosynthetic process
SRIM_RS00580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIM_RS00590	COG0251	oxidation-reduction process
SRIM_RS00600	COG1309	transcriptional regulator
SRIM_RS00640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIM_RS00645	COG0604	alcohol dehydrogenase
SRIM_RS00660	COG1254	Belongs to the acylphosphatase family
SRIM_RS00710	COG4644	lycopene metabolic process
SRIM_RS00735	COG0697	spore germination
SRIM_RS00745	COG2814	Major facilitator Superfamily
SRIM_RS00755	COG0596	Alpha beta hydrolase
SRIM_RS00775	COG0456	acetyltransferase
SRIM_RS00775	COG1214	PFAM Peptidase M22, glycoprotease
SRIM_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS00825	COG0137	argininosuccinate synthase activity
SRIM_RS00895	COG0384	phenazine biosynthesis protein PhzF
SRIM_RS00900	COG0583	DNA-binding transcription factor activity
SRIM_RS00935	COG2205	protein histidine kinase activity
SRIM_RS00980	COG0477	Major facilitator Superfamily
SRIM_RS01025	COG0583	DNA-binding transcription factor activity
SRIM_RS01030	COG0473	3-isopropylmalate dehydrogenase activity
SRIM_RS01035	COG1301	dicarboxylic acid transport
SRIM_RS01050	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS01055	COG0596	Alpha beta hydrolase
SRIM_RS01060	COG2208	phosphoserine phosphatase activity
SRIM_RS01060	COG2770	Histidine kinase
SRIM_RS01095	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SRIM_RS01100	COG1181	Belongs to the D-alanine--D-alanine ligase family
SRIM_RS01110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SRIM_RS01120	COG2205	protein histidine kinase activity
SRIM_RS01125	COG0745	RESPONSE REGULATOR receiver
SRIM_RS01145	COG0789	Transcriptional regulator
SRIM_RS01155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS01165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS01170	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIM_RS01190	COG3251	PFAM MbtH domain protein
SRIM_RS01195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS01235	COG0585	pseudouridine synthase activity
SRIM_RS01250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SRIM_RS01260	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS01285	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS01290	COG0657	acetylesterase activity
SRIM_RS01350	COG2124	cytochrome p450
SRIM_RS01355	COG2124	cytochrome p450
SRIM_RS01360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SRIM_RS01370	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS01385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SRIM_RS01405	COG0673	inositol 2-dehydrogenase activity
SRIM_RS01410	COG0640	Transcriptional regulator
SRIM_RS01415	COG1309	transcriptional regulator
SRIM_RS01420	COG0596	Alpha beta hydrolase
SRIM_RS01430	COG1191	sigma factor activity
SRIM_RS01450	COG1131	(ABC) transporter
SRIM_RS01465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS01470	COG2205	protein histidine kinase activity
SRIM_RS01475	COG0745	RESPONSE REGULATOR receiver
SRIM_RS01485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRIM_RS01500	COG0366	Alpha amylase catalytic
SRIM_RS01525	COG0346	lactoylglutathione lyase activity
SRIM_RS01540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS01545	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS01550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SRIM_RS01560	COG2271	Major facilitator Superfamily
SRIM_RS01570	COG0477	Major facilitator Superfamily
SRIM_RS01610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SRIM_RS01620	COG0300	oxidoreductase activity
SRIM_RS01625	COG0154	amidase activity
SRIM_RS01690	COG2259	Doxx family
SRIM_RS01695	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS01765	COG0583	DNA-binding transcription factor activity
SRIM_RS01780	COG3629	intracellular signal transduction
SRIM_RS01780	COG3903	Transcriptional regulator
SRIM_RS01795	COG2175	clavaminate synthase activity
SRIM_RS01810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIM_RS01835	COG1191	sigma factor activity
SRIM_RS01840	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIM_RS01845	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIM_RS01850	COG2172	sigma factor antagonist activity
SRIM_RS01860	COG2770	Histidine kinase
SRIM_RS01860	COG2208	phosphoserine phosphatase activity
SRIM_RS01890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SRIM_RS01900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SRIM_RS01915	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
SRIM_RS01955	COG2197	response regulator
SRIM_RS01995	COG4106	trans-aconitate 2-methyltransferase activity
SRIM_RS02020	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SRIM_RS02025	COG1228	amidohydrolase
SRIM_RS02060	COG0574	Belongs to the PEP-utilizing enzyme family
SRIM_RS02060	COG3848	Pyruvate phosphate dikinase
SRIM_RS02085	COG4221	oxidoreductase activity
SRIM_RS02090	COG0596	Alpha beta hydrolase
SRIM_RS02135	COG0494	nUDIX hydrolase
SRIM_RS02205	COG2732	(Barnase) inhibitor
SRIM_RS02240	COG0604	alcohol dehydrogenase
SRIM_RS02240	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS02240	COG3321	synthase
SRIM_RS02260	COG0583	DNA-binding transcription factor activity
SRIM_RS02290	COG2124	cytochrome p450
SRIM_RS02305	COG0367	asparagine synthase
SRIM_RS02330	COG0110	maltose O-acetyltransferase activity
SRIM_RS02350	COG4221	oxidoreductase activity
SRIM_RS02380	COG0671	phosphoesterase, PA-phosphatase related
SRIM_RS02445	COG0596	Alpha beta hydrolase
SRIM_RS02460	COG2124	cytochrome p450
SRIM_RS02555	COG0438	transferase activity, transferring glycosyl groups
SRIM_RS02565	COG2197	response regulator
SRIM_RS02570	COG4585	Histidine kinase
SRIM_RS02575	COG0829	nickel cation binding
SRIM_RS02585	COG0745	RESPONSE REGULATOR receiver
SRIM_RS02620	COG1316	TRANSCRIPTIONal
SRIM_RS02655	COG1116	anion transmembrane transporter activity
SRIM_RS02680	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SRIM_RS02685	COG0328	RNA-DNA hybrid ribonuclease activity
SRIM_RS02695	COG2207	Transcriptional regulator
SRIM_RS02700	COG1063	alcohol dehydrogenase
SRIM_RS02725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SRIM_RS02730	COG4977	sequence-specific DNA binding
SRIM_RS02735	COG2197	response regulator
SRIM_RS02740	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS02795	COG1482	cell wall glycoprotein biosynthetic process
SRIM_RS02800	COG0142	geranyltranstransferase activity
SRIM_RS02820	COG1657	PFAM Prenyltransferase squalene oxidase
SRIM_RS02850	COG2197	response regulator
SRIM_RS02885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS02900	COG3284	Transcriptional regulator
SRIM_RS02920	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS02955	COG0395	ABC-type sugar transport system, permease component
SRIM_RS02990	COG0395	ABC-type sugar transport system, permease component
SRIM_RS03005	COG1653	transport
SRIM_RS03030	COG2124	cytochrome p450
SRIM_RS03065	COG1191	sigma factor activity
SRIM_RS03085	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SRIM_RS03095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SRIM_RS03125	COG2378	regulation of single-species biofilm formation
SRIM_RS03140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS03190	COG1131	(ABC) transporter
SRIM_RS03205	COG2084	Dehydrogenase
SRIM_RS03210	COG3622	Belongs to the hyi family
SRIM_RS03215	COG3960	tartronate-semialdehyde synthase activity
SRIM_RS03220	COG0505	Belongs to the CarA family
SRIM_RS03245	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS03255	COG0242	peptide deformylase activity
SRIM_RS03265	COG3442	glutamine amidotransferase
SRIM_RS03270	COG0205	6-phosphofructokinase activity
SRIM_RS03310	COG0596	Alpha beta hydrolase
SRIM_RS03315	COG0477	Major facilitator Superfamily
SRIM_RS03320	COG1957	nucleoside hydrolase
SRIM_RS03325	COG1793	dna ligase
SRIM_RS03330	COG0395	ABC-type sugar transport system, permease component
SRIM_RS03335	COG1175	transmembrane transport
SRIM_RS03340	COG1653	transport
SRIM_RS03350	COG2222	sugar isomerase
SRIM_RS03355	COG1609	Transcriptional regulator
SRIM_RS03370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SRIM_RS03390	COG1063	alcohol dehydrogenase
SRIM_RS03415	COG3629	intracellular signal transduction
SRIM_RS03415	COG3903	Transcriptional regulator
SRIM_RS03420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIM_RS03425	COG2423	ornithine cyclodeaminase activity
SRIM_RS03440	COG3135	benzoate transporter
SRIM_RS03445	COG1473	amidohydrolase
SRIM_RS03460	COG0702	epimerase
SRIM_RS03510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SRIM_RS03520	COG3903	Transcriptional regulator
SRIM_RS03520	COG3629	intracellular signal transduction
SRIM_RS03525	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS03530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SRIM_RS03535	COG1454	alcohol dehydrogenase
SRIM_RS03560	COG0431	NADPH-dependent FMN reductase
SRIM_RS03580	COG0604	alcohol dehydrogenase
SRIM_RS03630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS03635	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS03650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS03655	COG0154	amidase activity
SRIM_RS03660	COG1309	transcriptional regulator
SRIM_RS03670	COG0829	nickel cation binding
SRIM_RS03675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SRIM_RS03680	COG0830	nickel cation binding
SRIM_RS03685	COG0804	urea catabolic process
SRIM_RS03690	COG0832	Belongs to the urease beta subunit family
SRIM_RS03695	COG0831	urea catabolic process
SRIM_RS03725	COG0740	serine-type endopeptidase activity
SRIM_RS03770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SRIM_RS03775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SRIM_RS03780	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SRIM_RS03785	COG2226	methyltransferase
SRIM_RS03805	COG0577	efflux transmembrane transporter activity
SRIM_RS03805	COG1136	(ABC) transporter
SRIM_RS03810	COG0577	efflux transmembrane transporter activity
SRIM_RS03815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIM_RS03855	COG0583	DNA-binding transcription factor activity
SRIM_RS03870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SRIM_RS03875	COG3663	DNA glycosylase
SRIM_RS03890	COG1940	carbohydrate kinase activity
SRIM_RS03905	COG2188	Transcriptional regulator
SRIM_RS03910	COG1595	DNA-templated transcription, initiation
SRIM_RS03950	COG2226	methyltransferase
SRIM_RS03960	COG1522	sequence-specific DNA binding
SRIM_RS03965	COG0419	ATPase involved in DNA repair
SRIM_RS03970	COG0420	3'-5' exonuclease activity
SRIM_RS03985	COG1132	(ABC) transporter
SRIM_RS03995	COG1113	amino acid transport
SRIM_RS04075	COG0667	Aldo Keto reductase
SRIM_RS04100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIM_RS04100	COG2146	nitrite reductase [NAD(P)H] activity
SRIM_RS04115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SRIM_RS04120	COG1882	Formate acetyltransferase
SRIM_RS04160	COG1140	nitrate reductase beta subunit
SRIM_RS04170	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SRIM_RS04180	COG2181	nitrate reductase activity
SRIM_RS04185	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SRIM_RS04190	COG1140	nitrate reductase beta subunit
SRIM_RS04200	COG0535	radical SAM domain protein
SRIM_RS04225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS04235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS04280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SRIM_RS04285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SRIM_RS04290	COG0823	Involved in the tonB-independent uptake of proteins
SRIM_RS04300	COG2706	6-phosphogluconolactonase activity
SRIM_RS04310	COG1597	lipid kinase activity
SRIM_RS04320	COG1846	Transcriptional regulator
SRIM_RS04335	COG0437	4 iron, 4 sulfur cluster binding
SRIM_RS04340	COG0243	molybdopterin cofactor binding
SRIM_RS04340	COG3383	formate dehydrogenase (NAD+) activity
SRIM_RS04345	COG1982	Orn Lys Arg decarboxylase major
SRIM_RS04350	COG1335	isochorismatase
SRIM_RS04380	COG1739	Uncharacterized protein family UPF0029
SRIM_RS04385	COG1832	CoA-binding protein
SRIM_RS04420	COG1309	transcriptional regulator
SRIM_RS04425	COG2124	cytochrome p450
SRIM_RS04430	COG1470	cell adhesion involved in biofilm formation
SRIM_RS04440	COG0110	maltose O-acetyltransferase activity
SRIM_RS04470	COG0300	oxidoreductase activity
SRIM_RS04475	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS04495	COG0248	Ppx GppA phosphatase
SRIM_RS04500	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIM_RS04510	COG1793	dna ligase
SRIM_RS04510	COG3285	dna ligase
SRIM_RS04555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SRIM_RS04570	COG1968	undecaprenyl-diphosphatase activity
SRIM_RS04590	COG2205	protein histidine kinase activity
SRIM_RS04595	COG0745	RESPONSE REGULATOR receiver
SRIM_RS04600	COG0438	transferase activity, transferring glycosyl groups
SRIM_RS04650	COG1595	DNA-templated transcription, initiation
SRIM_RS04665	COG4941	Belongs to the sigma-70 factor family
SRIM_RS04670	COG3795	YCII-related domain
SRIM_RS04700	COG0583	DNA-binding transcription factor activity
SRIM_RS04760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SRIM_RS04765	COG4733	cellulase activity
SRIM_RS04805	COG2205	protein histidine kinase activity
SRIM_RS04810	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SRIM_RS04825	COG0531	amino acid
SRIM_RS04830	COG0019	diaminopimelate decarboxylase activity
SRIM_RS04835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIM_RS04885	COG0531	amino acid
SRIM_RS04890	COG2267	carboxylic ester hydrolase activity
SRIM_RS04930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SRIM_RS04945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIM_RS04950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SRIM_RS04955	COG0386	Belongs to the glutathione peroxidase family
SRIM_RS04970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SRIM_RS04980	COG1252	NADH dehydrogenase
SRIM_RS04985	COG0640	Transcriptional regulator
SRIM_RS04995	COG1132	(ABC) transporter
SRIM_RS05030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SRIM_RS05035	COG0667	Aldo Keto reductase
SRIM_RS05060	COG0154	amidase activity
SRIM_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS05135	COG0823	Involved in the tonB-independent uptake of proteins
SRIM_RS05135	COG1506	peptidase
SRIM_RS05135	COG4946	Tricorn protease homolog
SRIM_RS05155	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS05160	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SRIM_RS05160	COG0825	malonyl-CoA metabolic process
SRIM_RS05175	COG0697	spore germination
SRIM_RS05180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SRIM_RS05200	COG0697	spore germination
SRIM_RS05215	COG1695	Transcriptional regulator
SRIM_RS05225	COG0789	Transcriptional regulator
SRIM_RS05235	COG0384	phenazine biosynthesis protein PhzF
SRIM_RS05260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SRIM_RS05260	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SRIM_RS05270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SRIM_RS05290	COG1716	ATPase activity
SRIM_RS05310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SRIM_RS05340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SRIM_RS05350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SRIM_RS05365	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SRIM_RS05375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIM_RS05380	COG3447	MASE1 domain protein
SRIM_RS05380	COG5001	Diguanylate cyclase
SRIM_RS05380	COG5002	protein histidine kinase activity
SRIM_RS05385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SRIM_RS05390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SRIM_RS05395	COG0442	prolyl-tRNA aminoacylation
SRIM_RS05445	COG2146	nitrite reductase [NAD(P)H] activity
SRIM_RS05490	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SRIM_RS05510	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SRIM_RS05515	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SRIM_RS05520	COG1984	allophanate hydrolase subunit 2
SRIM_RS05530	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SRIM_RS05545	COG0438	transferase activity, transferring glycosyl groups
SRIM_RS05550	COG0438	transferase activity, transferring glycosyl groups
SRIM_RS05595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIM_RS05600	COG2124	cytochrome p450
SRIM_RS05635	COG4221	oxidoreductase activity
SRIM_RS05690	COG1605	Chorismate mutase
SRIM_RS05735	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS05740	COG2366	antibiotic biosynthetic process
SRIM_RS05750	COG2070	2-Nitropropane dioxygenase
SRIM_RS05765	COG0515	serine threonine protein kinase
SRIM_RS05770	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS05775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SRIM_RS05800	COG0367	asparagine synthase
SRIM_RS05810	COG2318	DinB family
SRIM_RS05825	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIM_RS05825	COG2172	sigma factor antagonist activity
SRIM_RS05825	COG2208	phosphoserine phosphatase activity
SRIM_RS05865	COG4214	carbohydrate transport
SRIM_RS05880	COG3386	PFAM SMP-30 Gluconolaconase
SRIM_RS05885	COG1414	Transcriptional regulator
SRIM_RS05895	COG1309	transcriptional regulator
SRIM_RS05915	COG0596	Alpha beta hydrolase
SRIM_RS05930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SRIM_RS05970	COG2376	Dihydroxyacetone kinase
SRIM_RS05975	COG1461	Dihydroxyacetone kinase
SRIM_RS05985	COG1007	ATP synthesis coupled electron transport
SRIM_RS05990	COG1006	Multisubunit Na H antiporter MnhC subunit
SRIM_RS05995	COG2111	Na H antiporter
SRIM_RS06015	COG0640	Transcriptional regulator
SRIM_RS06060	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS06120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SRIM_RS06125	COG0463	Glycosyl transferase, family 2
SRIM_RS06165	COG0464	growth
SRIM_RS06175	COG1349	DNA-binding transcription factor activity
SRIM_RS06225	COG1940	carbohydrate kinase activity
SRIM_RS06245	COG2197	response regulator
SRIM_RS06250	COG4585	Histidine kinase
SRIM_RS06255	COG0644	oxidoreductase
SRIM_RS06275	COG0395	ABC-type sugar transport system, permease component
SRIM_RS06280	COG1175	transmembrane transport
SRIM_RS06290	COG3345	alpha-galactosidase
SRIM_RS06325	COG3973	AAA domain
SRIM_RS06340	COG2319	Wd-40 repeat
SRIM_RS06340	COG4249	Peptidase C14 caspase catalytic subunit p20
SRIM_RS06345	COG2318	DinB family
SRIM_RS06370	COG1191	sigma factor activity
SRIM_RS06380	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SRIM_RS06425	COG0584	glycerophosphoryl diester phosphodiesterase
SRIM_RS06450	COG0671	phosphoesterase, PA-phosphatase related
SRIM_RS06505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SRIM_RS06510	COG0140	phosphoribosyl-ATP diphosphatase activity
SRIM_RS06515	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SRIM_RS06520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SRIM_RS06520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SRIM_RS06525	COG3201	nicotinamide mononucleotide transporter
SRIM_RS06540	COG0702	epimerase
SRIM_RS06545	COG1846	Transcriptional regulator
SRIM_RS06545	COG1940	carbohydrate kinase activity
SRIM_RS06550	COG0738	Major facilitator superfamily
SRIM_RS06560	COG2233	PERMEase
SRIM_RS06580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SRIM_RS06600	COG0531	amino acid
SRIM_RS06640	COG2390	Transcriptional regulator
SRIM_RS06645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SRIM_RS06655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SRIM_RS06690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SRIM_RS06715	COG0284	orotidine-5'-phosphate decarboxylase activity
SRIM_RS06720	COG0167	dihydroorotate dehydrogenase activity
SRIM_RS06725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SRIM_RS06730	COG0505	Belongs to the CarA family
SRIM_RS06740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SRIM_RS06745	COG0540	Belongs to the ATCase OTCase family
SRIM_RS06750	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SRIM_RS06760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SRIM_RS06765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SRIM_RS06770	COG0006	proline dipeptidase activity
SRIM_RS06780	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SRIM_RS06785	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SRIM_RS06790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SRIM_RS06795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SRIM_RS06800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SRIM_RS06810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SRIM_RS06815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SRIM_RS06835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SRIM_RS06855	COG0124	histidyl-tRNA synthetase
SRIM_RS06865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SRIM_RS06870	COG1196	nuclear chromosome segregation
SRIM_RS06875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SRIM_RS06880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SRIM_RS06885	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SRIM_RS06890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SRIM_RS06900	COG2255	four-way junction helicase activity
SRIM_RS06905	COG0632	four-way junction helicase activity
SRIM_RS06910	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SRIM_RS06915	COG0217	transcriptional regulatory protein
SRIM_RS06920	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SRIM_RS06925	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SRIM_RS06940	COG0438	transferase activity, transferring glycosyl groups
SRIM_RS06945	COG1560	Kdo2-lipid A biosynthetic process
SRIM_RS06950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SRIM_RS06980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SRIM_RS06995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SRIM_RS07055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SRIM_RS07115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SRIM_RS07120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SRIM_RS07120	COG1648	precorrin-2 dehydrogenase activity
SRIM_RS07125	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SRIM_RS07140	COG1464	Belongs to the NlpA lipoprotein family
SRIM_RS07145	COG2011	ABC-type metal ion transport system permease component
SRIM_RS07150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SRIM_RS07175	COG0584	glycerophosphoryl diester phosphodiesterase
SRIM_RS07185	COG0737	Belongs to the 5'-nucleotidase family
SRIM_RS07190	COG0477	Major facilitator Superfamily
SRIM_RS07200	COG0165	Argininosuccinate lyase
SRIM_RS07205	COG0137	argininosuccinate synthase activity
SRIM_RS07260	COG1228	amidohydrolase
SRIM_RS07265	COG1438	arginine binding
SRIM_RS07270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRIM_RS07275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SRIM_RS07280	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SRIM_RS07285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SRIM_RS07300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIM_RS07330	COG2197	response regulator
SRIM_RS07335	COG4585	Histidine kinase
SRIM_RS07350	COG2838	Isocitrate dehydrogenase
SRIM_RS07375	COG1660	Displays ATPase and GTPase activities
SRIM_RS07380	COG1595	DNA-templated transcription, initiation
SRIM_RS07415	COG2182	Extracellular solute-binding protein
SRIM_RS07420	COG1175	transmembrane transport
SRIM_RS07425	COG0395	ABC-type sugar transport system, permease component
SRIM_RS07430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SRIM_RS07435	COG1486	melibiose metabolic process
SRIM_RS07450	COG0697	spore germination
SRIM_RS07460	COG1649	PFAM Uncharacterised BCR, COG1649
SRIM_RS07490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SRIM_RS07490	COG0072	phenylalanine-tRNA ligase activity
SRIM_RS07495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SRIM_RS07500	COG5002	protein histidine kinase activity
SRIM_RS07505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SRIM_RS07510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SRIM_RS07515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SRIM_RS07520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SRIM_RS07530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SRIM_RS07570	COG0174	glutamine synthetase
SRIM_RS07575	COG2186	Transcriptional regulator
SRIM_RS07580	COG0531	amino acid
SRIM_RS07585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SRIM_RS07605	COG4176	ABC-type proline glycine betaine transport system permease component
SRIM_RS07610	COG0517	IMP dehydrogenase activity
SRIM_RS07610	COG4175	Glycine betaine
SRIM_RS07615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SRIM_RS07630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIM_RS07640	COG0805	protein transport
SRIM_RS07645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SRIM_RS07665	COG2378	regulation of single-species biofilm formation
SRIM_RS07680	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SRIM_RS07690	COG1609	Transcriptional regulator
SRIM_RS07695	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SRIM_RS07700	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SRIM_RS07710	COG4122	O-methyltransferase activity
SRIM_RS07715	COG1222	aaa ATPase
SRIM_RS07735	COG0517	IMP dehydrogenase activity
SRIM_RS07735	COG1994	Peptidase M50
SRIM_RS07745	COG2197	response regulator
SRIM_RS07755	COG4166	transmembrane transport
SRIM_RS07765	COG0646	methionine synthase
SRIM_RS07765	COG1410	methionine synthase
SRIM_RS07770	COG1414	Transcriptional regulator
SRIM_RS07775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SRIM_RS07780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SRIM_RS07785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SRIM_RS07790	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SRIM_RS07795	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SRIM_RS07805	COG0235	Class ii aldolase
SRIM_RS07810	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SRIM_RS07815	COG0402	S-adenosylhomocysteine deaminase activity
SRIM_RS07820	COG2186	Transcriptional regulator
SRIM_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS07845	COG4211	Belongs to the binding-protein-dependent transport system permease family
SRIM_RS07850	COG1129	ABC transporter
SRIM_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS07865	COG4948	Mandelate Racemase Muconate Lactonizing
SRIM_RS07890	COG0215	cysteine-tRNA ligase activity
SRIM_RS07910	COG0598	Magnesium transport protein CorA
SRIM_RS07920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIM_RS07925	COG0667	Aldo Keto reductase
SRIM_RS07955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIM_RS08050	COG0488	(ABC) transporter
SRIM_RS08055	COG2124	cytochrome p450
SRIM_RS08080	COG0745	RESPONSE REGULATOR receiver
SRIM_RS08085	COG5002	protein histidine kinase activity
SRIM_RS08090	COG3173	Aminoglycoside phosphotransferase
SRIM_RS08125	COG3573	Dehydrogenase
SRIM_RS08150	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SRIM_RS08155	COG2149	membrane
SRIM_RS08170	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS08175	COG0456	acetyltransferase
SRIM_RS08175	COG1846	Transcriptional regulator
SRIM_RS08185	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS08195	COG3876	Protein conserved in bacteria
SRIM_RS08200	COG0477	Major facilitator Superfamily
SRIM_RS08240	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS08300	COG2851	Citrate transporter
SRIM_RS08305	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SRIM_RS08310	COG2188	Transcriptional regulator
SRIM_RS08315	COG4195	phage-related replication protein
SRIM_RS08320	COG0477	Major facilitator Superfamily
SRIM_RS08320	COG2814	Major facilitator Superfamily
SRIM_RS08330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIM_RS08345	COG1595	DNA-templated transcription, initiation
SRIM_RS08365	COG0515	serine threonine protein kinase
SRIM_RS08365	COG2815	serine threonine protein kinase
SRIM_RS08385	COG0463	Glycosyl transferase, family 2
SRIM_RS08390	COG1215	transferase activity, transferring glycosyl groups
SRIM_RS08395	COG0726	polysaccharide deacetylase
SRIM_RS08415	COG1834	amidinotransferase
SRIM_RS08425	COG1725	Transcriptional regulator
SRIM_RS08455	COG0019	diaminopimelate decarboxylase activity
SRIM_RS08485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SRIM_RS08490	COG0587	DNA-directed DNA polymerase activity
SRIM_RS08500	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS08510	COG0326	Molecular chaperone. Has ATPase activity
SRIM_RS08550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIM_RS08555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIM_RS08565	COG1799	cell septum assembly
SRIM_RS08570	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS08575	COG0477	Major facilitator Superfamily
SRIM_RS08585	COG0671	phosphoesterase, PA-phosphatase related
SRIM_RS08645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SRIM_RS08680	COG0411	ABC transporter
SRIM_RS08710	COG1160	GTP binding
SRIM_RS08720	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SRIM_RS08745	COG3541	Predicted nucleotidyltransferase
SRIM_RS08755	COG1187	pseudouridine synthase activity
SRIM_RS08760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SRIM_RS08765	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SRIM_RS08780	COG0686	Belongs to the AlaDH PNT family
SRIM_RS08790	COG0494	nUDIX hydrolase
SRIM_RS08795	COG0504	CTP synthase activity
SRIM_RS08800	COG3387	PFAM Glycoside hydrolase 15-related
SRIM_RS08830	COG0438	transferase activity, transferring glycosyl groups
SRIM_RS08840	COG0497	DNA recombination
SRIM_RS08860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SRIM_RS08880	COG1120	ATPase activity
SRIM_RS08885	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS08890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS08905	COG0647	UMP catabolic process
SRIM_RS08920	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SRIM_RS08960	COG2094	Belongs to the DNA glycosylase MPG family
SRIM_RS08970	COG1881	PFAM PEBP family protein
SRIM_RS08995	COG1119	ATPase activity
SRIM_RS09015	COG2197	response regulator
SRIM_RS09020	COG4585	Histidine kinase
SRIM_RS09025	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS09030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SRIM_RS09045	COG1716	ATPase activity
SRIM_RS09045	COG0842	Transport permease protein
SRIM_RS09045	COG1131	(ABC) transporter
SRIM_RS09055	COG0560	Phosphoserine phosphatase
SRIM_RS09055	COG3830	Belongs to the UPF0237 family
SRIM_RS09070	COG2807	transmembrane transport
SRIM_RS09075	COG2186	Transcriptional regulator
SRIM_RS09080	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SRIM_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS09100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SRIM_RS09105	COG2261	transglycosylase associated protein
SRIM_RS09120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SRIM_RS09125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SRIM_RS09165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SRIM_RS09180	COG3387	PFAM Glycoside hydrolase 15-related
SRIM_RS09210	COG1302	Protein conserved in bacteria
SRIM_RS09220	COG1024	Enoyl-CoA hydratase
SRIM_RS09230	COG0488	(ABC) transporter
SRIM_RS09255	COG0235	Class ii aldolase
SRIM_RS09275	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SRIM_RS09290	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SRIM_RS09295	COG1797	cobyrinic acid a,c-diamide synthase activity
SRIM_RS09320	COG0385	Bile acid
SRIM_RS09335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SRIM_RS09340	COG1917	Cupin 2, conserved barrel domain protein
SRIM_RS09345	COG5285	phytanoyl-CoA dioxygenase
SRIM_RS09380	COG0456	acetyltransferase
SRIM_RS09390	COG1414	Transcriptional regulator
SRIM_RS09395	COG4585	Histidine kinase
SRIM_RS09425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRIM_RS09430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SRIM_RS09435	COG2261	transglycosylase associated protein
SRIM_RS09470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIM_RS09500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRIM_RS09520	COG2171	N-acyltransferase activity
SRIM_RS09530	COG3226	Transcriptional regulator
SRIM_RS09535	COG2076	Multidrug Resistance protein
SRIM_RS09560	COG0822	iron-sulfur transferase activity
SRIM_RS09565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SRIM_RS09570	COG0396	ATPase activity
SRIM_RS09580	COG0719	Fe-S assembly protein
SRIM_RS09605	COG1612	heme a metabolic process
SRIM_RS09620	COG0109	protoheme IX farnesyltransferase activity
SRIM_RS09625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SRIM_RS09630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SRIM_RS09645	COG0363	glucosamine-6-phosphate deaminase activity
SRIM_RS09655	COG0166	Belongs to the GPI family
SRIM_RS09665	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SRIM_RS09675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SRIM_RS09685	COG0454	-acetyltransferase
SRIM_RS09685	COG0456	acetyltransferase
SRIM_RS09690	COG1481	regulation of sporulation
SRIM_RS09700	COG1660	Displays ATPase and GTPase activities
SRIM_RS09705	COG0322	excinuclease ABC activity
SRIM_RS09745	COG2814	Major facilitator Superfamily
SRIM_RS09750	COG1063	alcohol dehydrogenase
SRIM_RS09765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SRIM_RS09810	COG0556	nucleotide-excision repair
SRIM_RS09815	COG0584	glycerophosphoryl diester phosphodiesterase
SRIM_RS09860	COG4279	zinc finger
SRIM_RS09865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SRIM_RS09890	COG0237	dephospho-CoA kinase activity
SRIM_RS09915	COG2226	methyltransferase
SRIM_RS09920	COG1643	Atp-dependent helicase
SRIM_RS09955	COG2050	protein possibly involved in aromatic compounds catabolism
SRIM_RS10010	COG0737	Belongs to the 5'-nucleotidase family
SRIM_RS10040	COG0366	Alpha amylase catalytic
SRIM_RS10040	COG1470	cell adhesion involved in biofilm formation
SRIM_RS10050	COG2197	response regulator
SRIM_RS10070	COG0464	growth
SRIM_RS10105	COG0596	Alpha beta hydrolase
SRIM_RS10110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SRIM_RS10125	COG3467	pyridoxamine 5'-phosphate
SRIM_RS10130	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS10135	COG1846	Transcriptional regulator
SRIM_RS10145	COG0067	glutamate synthase
SRIM_RS10145	COG0069	glutamate synthase activity
SRIM_RS10145	COG0070	glutamate synthase
SRIM_RS10155	COG1609	Transcriptional regulator
SRIM_RS10180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIM_RS10185	COG2301	Belongs to the HpcH HpaI aldolase family
SRIM_RS10190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SRIM_RS10200	COG0159	tryptophan synthase activity
SRIM_RS10205	COG0133	tryptophan synthase activity
SRIM_RS10215	COG0134	indole-3-glycerol-phosphate synthase activity
SRIM_RS10240	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SRIM_RS10260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SRIM_RS10270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SRIM_RS10275	COG0583	DNA-binding transcription factor activity
SRIM_RS10285	COG1053	succinate dehydrogenase
SRIM_RS10290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SRIM_RS10305	COG0107	imidazoleglycerol-phosphate synthase activity
SRIM_RS10310	COG0251	oxidation-reduction process
SRIM_RS10315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SRIM_RS10320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SRIM_RS10330	COG0131	Imidazoleglycerol-phosphate dehydratase
SRIM_RS10335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SRIM_RS10340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SRIM_RS10355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SRIM_RS10375	COG1432	Conserved Protein
SRIM_RS10385	COG0587	DNA-directed DNA polymerase activity
SRIM_RS10440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SRIM_RS10450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SRIM_RS10455	COG3599	regulation of cell shape
SRIM_RS10465	COG1799	cell septum assembly
SRIM_RS10485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SRIM_RS10490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SRIM_RS10500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SRIM_RS10505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SRIM_RS10515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SRIM_RS10520	COG0768	penicillin binding
SRIM_RS10530	COG0275	rRNA processing
SRIM_RS10540	COG0714	Associated with various cellular activities
SRIM_RS10560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIM_RS10580	COG1309	transcriptional regulator
SRIM_RS10590	COG1233	COG1233 Phytoene dehydrogenase and related
SRIM_RS10605	COG0352	thiamine-phosphate diphosphorylase activity
SRIM_RS10620	COG2022	thiamine diphosphate biosynthetic process
SRIM_RS10620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIM_RS10630	COG2022	thiamine diphosphate biosynthetic process
SRIM_RS10635	COG2815	serine threonine protein kinase
SRIM_RS10635	COG0515	serine threonine protein kinase
SRIM_RS10640	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SRIM_RS10650	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SRIM_RS10655	COG2193	ferroxidase activity
SRIM_RS10665	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SRIM_RS10670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIM_RS10675	COG2267	carboxylic ester hydrolase activity
SRIM_RS10685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SRIM_RS10690	COG0205	6-phosphofructokinase activity
SRIM_RS10695	COG2197	response regulator
SRIM_RS10730	COG1940	carbohydrate kinase activity
SRIM_RS10740	COG0003	Pfam Anion-transporting ATPase
SRIM_RS10760	COG0438	transferase activity, transferring glycosyl groups
SRIM_RS10775	COG0791	NLP P60 protein
SRIM_RS10775	COG3883	PFAM NLP P60 protein
SRIM_RS10795	COG0705	Rhomboid family
SRIM_RS10805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SRIM_RS10810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SRIM_RS10815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SRIM_RS10820	COG0723	plastoquinol--plastocyanin reductase activity
SRIM_RS10825	COG2010	Cytochrome c
SRIM_RS10830	COG1845	cytochrome c oxidase, subunit III
SRIM_RS10840	COG1376	ErfK ybiS ycfS ynhG family protein
SRIM_RS10850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SRIM_RS10855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SRIM_RS10865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SRIM_RS10885	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SRIM_RS10890	COG2161	toxin-antitoxin pair type II binding
SRIM_RS10900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SRIM_RS10905	COG2197	response regulator
SRIM_RS10910	COG4585	Histidine kinase
SRIM_RS10930	COG2226	methyltransferase
SRIM_RS10935	COG1132	(ABC) transporter
SRIM_RS10940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRIM_RS10960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SRIM_RS10965	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SRIM_RS10965	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SRIM_RS10980	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SRIM_RS11005	COG0438	transferase activity, transferring glycosyl groups
SRIM_RS11015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SRIM_RS11020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SRIM_RS11025	COG0508	dehydrogenase complex catalyzes the overall conversion of
SRIM_RS11035	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SRIM_RS11060	COG1090	epimerase
SRIM_RS11075	COG0321	lipoyl(octanoyl) transferase activity
SRIM_RS11080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SRIM_RS11125	COG2205	protein histidine kinase activity
SRIM_RS11130	COG0745	RESPONSE REGULATOR receiver
SRIM_RS11135	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS11150	COG0673	inositol 2-dehydrogenase activity
SRIM_RS11155	COG3591	Belongs to the peptidase S1B family
SRIM_RS11170	COG0745	RESPONSE REGULATOR receiver
SRIM_RS11185	COG4585	Histidine kinase
SRIM_RS11190	COG2197	response regulator
SRIM_RS11215	COG1309	transcriptional regulator
SRIM_RS11270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIM_RS11295	COG0366	Alpha amylase catalytic
SRIM_RS11300	COG3833	ABC-type maltose transport systems, permease component
SRIM_RS11305	COG1175	transmembrane transport
SRIM_RS11310	COG2182	Extracellular solute-binding protein
SRIM_RS11315	COG0366	Alpha amylase catalytic
SRIM_RS11320	COG1609	Transcriptional regulator
SRIM_RS11330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SRIM_RS11335	COG0174	glutamine synthetase
SRIM_RS11360	COG2132	Multicopper oxidase
SRIM_RS11365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SRIM_RS11365	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SRIM_RS11375	COG2814	Major facilitator Superfamily
SRIM_RS11390	COG0477	Major facilitator Superfamily
SRIM_RS11395	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SRIM_RS11400	COG1687	branched-chain amino acid
SRIM_RS11430	COG1994	Peptidase M50
SRIM_RS11435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIM_RS11460	COG0395	ABC-type sugar transport system, permease component
SRIM_RS11465	COG1175	transmembrane transport
SRIM_RS11495	COG5398	heme oxygenase
SRIM_RS11515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SRIM_RS11520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS11525	COG1120	ATPase activity
SRIM_RS11535	COG2837	iron assimilation
SRIM_RS11540	COG0672	)-iron permease
SRIM_RS11565	COG1834	amidinotransferase
SRIM_RS11575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRIM_RS11580	COG2814	Major facilitator Superfamily
SRIM_RS11585	COG3540	Alkaline phosphatase
SRIM_RS11610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SRIM_RS11640	COG0535	radical SAM domain protein
SRIM_RS11645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIM_RS11785	COG0776	regulation of translation
SRIM_RS12140	COG3629	intracellular signal transduction
SRIM_RS12140	COG3903	Transcriptional regulator
SRIM_RS12145	COG1957	nucleoside hydrolase
SRIM_RS12155	COG0789	Transcriptional regulator
SRIM_RS12165	COG0557	exoribonuclease II activity
SRIM_RS12170	COG3022	response to hydroperoxide
SRIM_RS12175	COG0800	Aldolase
SRIM_RS12180	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SRIM_RS12195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SRIM_RS12215	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS12225	COG2030	dehydratase
SRIM_RS12230	COG4585	Histidine kinase
SRIM_RS12270	COG2197	response regulator
SRIM_RS12275	COG0509	glycine decarboxylation via glycine cleavage system
SRIM_RS12280	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS12290	COG0183	Belongs to the thiolase family
SRIM_RS12295	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS12305	COG0860	N-Acetylmuramoyl-L-alanine amidase
SRIM_RS12315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIM_RS12350	COG1309	transcriptional regulator
SRIM_RS12355	COG1132	(ABC) transporter
SRIM_RS12360	COG1132	(ABC) transporter
SRIM_RS12370	COG0515	serine threonine protein kinase
SRIM_RS12390	COG1657	PFAM Prenyltransferase squalene oxidase
SRIM_RS12405	COG3845	ABC transporter
SRIM_RS12430	COG2318	DinB family
SRIM_RS12440	COG0183	Belongs to the thiolase family
SRIM_RS12445	COG2124	cytochrome p450
SRIM_RS12470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SRIM_RS12485	COG0667	Aldo Keto reductase
SRIM_RS12495	COG0477	Major facilitator Superfamily
SRIM_RS12530	COG0456	acetyltransferase
SRIM_RS12540	COG3409	Peptidoglycan-binding domain 1 protein
SRIM_RS12540	COG0860	N-Acetylmuramoyl-L-alanine amidase
SRIM_RS12545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SRIM_RS12570	COG2259	Doxx family
SRIM_RS12600	COG1072	(Pantothenic acid kinase))
SRIM_RS12665	COG1120	ATPase activity
SRIM_RS12680	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SRIM_RS12690	COG2259	Doxx family
SRIM_RS12715	COG4948	Mandelate Racemase Muconate Lactonizing
SRIM_RS12740	COG4585	Histidine kinase
SRIM_RS12745	COG0586	Pfam SNARE associated Golgi protein
SRIM_RS12800	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SRIM_RS12815	COG0477	Major facilitator Superfamily
SRIM_RS12820	COG1309	transcriptional regulator
SRIM_RS12835	COG4585	Histidine kinase
SRIM_RS12840	COG2197	response regulator
SRIM_RS12855	COG0667	Aldo Keto reductase
SRIM_RS12860	COG0789	Transcriptional regulator
SRIM_RS12885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIM_RS12890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIM_RS12895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIM_RS12945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SRIM_RS12955	COG1172	Belongs to the binding-protein-dependent transport system permease family
SRIM_RS12970	COG1764	response to oxidative stress
SRIM_RS12975	COG2130	NADP-dependent
SRIM_RS12985	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SRIM_RS12995	COG0477	Major facilitator Superfamily
SRIM_RS13025	COG0500	methyltransferase
SRIM_RS13030	COG4981	capsule polysaccharide biosynthetic process
SRIM_RS13060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SRIM_RS13070	COG1077	Cell shape determining protein MreB Mrl
SRIM_RS13080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SRIM_RS13085	COG2080	2 iron, 2 sulfur cluster binding
SRIM_RS13085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SRIM_RS13095	COG3835	regulator
SRIM_RS13110	COG1834	amidinotransferase
SRIM_RS13140	COG1070	Carbohydrate kinase
SRIM_RS13145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SRIM_RS13150	COG0358	DNA primase activity
SRIM_RS13165	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SRIM_RS13175	COG0243	molybdopterin cofactor binding
SRIM_RS13190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SRIM_RS13230	COG2382	esterase
SRIM_RS13260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIM_RS13275	COG2197	response regulator
SRIM_RS13285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIM_RS13290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIM_RS13290	COG2146	nitrite reductase [NAD(P)H] activity
SRIM_RS13310	COG0531	amino acid
SRIM_RS13320	COG3485	protocatechuate 3,4-dioxygenase
SRIM_RS13350	COG2814	Major facilitator Superfamily
SRIM_RS13360	COG0789	Transcriptional regulator
SRIM_RS13365	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS13375	COG1175	transmembrane transport
SRIM_RS13380	COG0395	ABC-type sugar transport system, permease component
SRIM_RS13390	COG2175	clavaminate synthase activity
SRIM_RS13400	COG0574	Belongs to the PEP-utilizing enzyme family
SRIM_RS13400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SRIM_RS13420	COG0477	Major facilitator Superfamily
SRIM_RS13425	COG0667	Aldo Keto reductase
SRIM_RS13440	COG2197	response regulator
SRIM_RS13455	COG0423	glycine-tRNA ligase activity
SRIM_RS13465	COG1121	(ABC) transporter
SRIM_RS13470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SRIM_RS13480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SRIM_RS13485	COG1381	Involved in DNA repair and RecF pathway recombination
SRIM_RS13495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SRIM_RS13510	COG2723	6-phospho-beta-galactosidase activity
SRIM_RS13520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SRIM_RS13525	COG0475	glutathione-regulated potassium exporter activity
SRIM_RS13540	COG0492	ferredoxin-NADP+ reductase activity
SRIM_RS13545	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS13580	COG2814	Major facilitator Superfamily
SRIM_RS13590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SRIM_RS13600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SRIM_RS13605	COG1486	melibiose metabolic process
SRIM_RS13620	COG4948	Mandelate Racemase Muconate Lactonizing
SRIM_RS13630	COG1234	tRNA 3'-trailer cleavage
SRIM_RS13635	COG0537	adenosine 5'-monophosphoramidase activity
SRIM_RS13660	COG0484	heat shock protein binding
SRIM_RS13665	COG1420	regulation of RNA biosynthetic process
SRIM_RS13700	COG3437	response regulator, receiver
SRIM_RS13705	COG1022	Amp-dependent synthetase and ligase
SRIM_RS13715	COG0481	GTPase activity
SRIM_RS13720	COG0268	Binds directly to 16S ribosomal RNA
SRIM_RS13745	COG1959	2 iron, 2 sulfur cluster binding
SRIM_RS13750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SRIM_RS13755	COG1234	tRNA 3'-trailer cleavage
SRIM_RS13760	COG1555	photosystem II stabilization
SRIM_RS13760	COG1596	polysaccharide export
SRIM_RS13765	COG1307	EDD domain protein, DegV family
SRIM_RS13775	COG0495	leucyl-tRNA aminoacylation
SRIM_RS13825	COG0588	phosphoglycerate mutase activity
SRIM_RS13830	COG0799	negative regulation of ribosome biogenesis
SRIM_RS13840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SRIM_RS13855	COG0501	Belongs to the peptidase M48B family
SRIM_RS13870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SRIM_RS13880	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SRIM_RS13885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SRIM_RS13890	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SRIM_RS13895	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SRIM_RS13900	COG1530	ribonuclease E activity
SRIM_RS13925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIM_RS13925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIM_RS13930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SRIM_RS13940	COG0772	Belongs to the SEDS family
SRIM_RS13960	COG1077	Cell shape determining protein MreB Mrl
SRIM_RS13965	COG0105	UTP biosynthetic process
SRIM_RS13975	COG0285	dihydrofolate synthase activity
SRIM_RS13980	COG0768	penicillin binding
SRIM_RS13990	COG0525	valine-tRNA ligase activity
SRIM_RS14005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SRIM_RS14010	COG0740	serine-type endopeptidase activity
SRIM_RS14015	COG0740	serine-type endopeptidase activity
SRIM_RS14020	COG0544	peptidyl-prolyl cis-trans isomerase activity
SRIM_RS14045	COG3594	Acyltransferase
SRIM_RS14050	COG1136	(ABC) transporter
SRIM_RS14055	COG0475	glutathione-regulated potassium exporter activity
SRIM_RS14070	COG4552	Acetyltransferase involved in intracellular survival and related
SRIM_RS14090	COG0515	serine threonine protein kinase
SRIM_RS14100	COG1268	BioY protein
SRIM_RS14105	COG1113	amino acid transport
SRIM_RS14110	COG1113	amino acid transport
SRIM_RS14115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SRIM_RS14120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SRIM_RS14155	COG2337	Toxic component of a toxin-antitoxin (TA) module
SRIM_RS14175	COG4266	Belongs to the allantoicase family
SRIM_RS14180	COG0583	DNA-binding transcription factor activity
SRIM_RS14210	COG3291	Pkd domain containing protein
SRIM_RS14210	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SRIM_RS14220	COG0668	transmembrane transport
SRIM_RS14250	COG2080	2 iron, 2 sulfur cluster binding
SRIM_RS14255	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SRIM_RS14260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SRIM_RS14290	COG1846	Transcriptional regulator
SRIM_RS14290	COG1940	carbohydrate kinase activity
SRIM_RS14300	COG1175	transmembrane transport
SRIM_RS14305	COG0395	ABC-type sugar transport system, permease component
SRIM_RS14310	COG1486	melibiose metabolic process
SRIM_RS14325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRIM_RS14355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIM_RS14360	COG2346	COG2346, Truncated hemoglobins
SRIM_RS14385	COG0629	single-stranded DNA binding
SRIM_RS14390	COG1160	GTP binding
SRIM_RS14495	COG1077	Cell shape determining protein MreB Mrl
SRIM_RS14525	COG1131	(ABC) transporter
SRIM_RS14545	COG3962	Belongs to the TPP enzyme family
SRIM_RS14550	COG3718	enzyme involved in inositol metabolism
SRIM_RS14560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SRIM_RS14570	COG0673	inositol 2-dehydrogenase activity
SRIM_RS14575	COG1082	Xylose isomerase domain protein TIM barrel
SRIM_RS14580	COG2814	Major facilitator Superfamily
SRIM_RS14595	COG0673	inositol 2-dehydrogenase activity
SRIM_RS14605	COG0569	domain protein
SRIM_RS14605	COG0475	glutathione-regulated potassium exporter activity
SRIM_RS14625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SRIM_RS14640	COG0673	inositol 2-dehydrogenase activity
SRIM_RS14645	COG1609	Transcriptional regulator
SRIM_RS14660	COG1472	Belongs to the glycosyl hydrolase 3 family
SRIM_RS14695	COG1132	(ABC) transporter
SRIM_RS14700	COG1511	domain protein
SRIM_RS14705	COG1309	transcriptional regulator
SRIM_RS14710	COG0281	malic enzyme
SRIM_RS14720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SRIM_RS14765	COG1946	Acyl-CoA thioesterase
SRIM_RS14775	COG1309	transcriptional regulator
SRIM_RS14780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SRIM_RS14795	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS14810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SRIM_RS14815	COG0589	response to stress
SRIM_RS14825	COG4977	sequence-specific DNA binding
SRIM_RS14830	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SRIM_RS14840	COG2910	NAD(P)H-binding
SRIM_RS14855	COG5297	Belongs to the glycosyl hydrolase family 6
SRIM_RS14885	COG3979	chitinase
SRIM_RS14920	COG0588	phosphoglycerate mutase activity
SRIM_RS14970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIM_RS14990	COG0154	amidase activity
SRIM_RS15005	COG0765	amino acid transport
SRIM_RS15010	COG0765	amino acid transport
SRIM_RS15015	COG1126	abc transporter atp-binding protein
SRIM_RS15030	COG3397	chitin binding
SRIM_RS15035	COG3397	chitin binding
SRIM_RS15065	COG2186	Transcriptional regulator
SRIM_RS15105	COG1840	ABC-type Fe3 transport system, periplasmic component
SRIM_RS15135	COG2188	Transcriptional regulator
SRIM_RS15150	COG0673	inositol 2-dehydrogenase activity
SRIM_RS15155	COG4702	Belongs to the UPF0303 family
SRIM_RS15165	COG0179	Fumarylacetoacetate (FAA) hydrolase
SRIM_RS15170	COG0706	membrane insertase activity
SRIM_RS15190	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SRIM_RS15200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SRIM_RS15210	COG3764	Sortase (surface protein transpeptidase)
SRIM_RS15215	COG2733	membrane
SRIM_RS15245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRIM_RS15255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SRIM_RS15270	COG2205	protein histidine kinase activity
SRIM_RS15300	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SRIM_RS15315	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SRIM_RS15320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SRIM_RS15325	COG1263	PTS System
SRIM_RS15330	COG1263	PTS System
SRIM_RS15335	COG1234	tRNA 3'-trailer cleavage
SRIM_RS15355	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SRIM_RS15360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS15375	COG1113	amino acid transport
SRIM_RS15385	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SRIM_RS15395	COG1335	isochorismatase
SRIM_RS15440	COG0222	ribosome binding
SRIM_RS15445	COG0277	FAD linked oxidase domain protein
SRIM_RS15450	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SRIM_RS15460	COG1174	glycine betaine transport
SRIM_RS15470	COG1174	glycine betaine transport
SRIM_RS15475	COG1732	Glycine betaine
SRIM_RS15495	COG0477	Major facilitator Superfamily
SRIM_RS15500	COG2201	protein-glutamate methylesterase activity
SRIM_RS15515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SRIM_RS15530	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SRIM_RS15535	COG0395	ABC-type sugar transport system, permease component
SRIM_RS15540	COG1175	transmembrane transport
SRIM_RS15560	COG2814	Major facilitator Superfamily
SRIM_RS15570	COG0583	DNA-binding transcription factor activity
SRIM_RS15575	COG1678	Uncharacterized ACR, COG1678
SRIM_RS15580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SRIM_RS15585	COG0776	regulation of translation
SRIM_RS15595	COG3973	AAA domain
SRIM_RS15625	COG2223	nitrite transmembrane transporter activity
SRIM_RS15670	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SRIM_RS15675	COG0793	Belongs to the peptidase S41A family
SRIM_RS15680	COG2177	Part of the ABC transporter FtsEX involved in
SRIM_RS15685	COG2884	Cell division ATP-binding protein ftsE
SRIM_RS15700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SRIM_RS15705	COG0515	serine threonine protein kinase
SRIM_RS15710	COG0515	serine threonine protein kinase
SRIM_RS15715	COG1674	ftsk spoiiie
SRIM_RS15720	COG1653	transport
SRIM_RS15725	COG1175	transmembrane transport
SRIM_RS15730	COG0395	ABC-type sugar transport system, permease component
SRIM_RS15740	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SRIM_RS15745	COG1215	transferase activity, transferring glycosyl groups
SRIM_RS15755	COG0463	Glycosyl transferase, family 2
SRIM_RS15760	COG0438	transferase activity, transferring glycosyl groups
SRIM_RS15765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SRIM_RS15775	COG0463	Glycosyl transferase, family 2
SRIM_RS15790	COG1309	transcriptional regulator
SRIM_RS15800	COG1134	teichoic acid transport
SRIM_RS15830	COG0653	protein targeting
SRIM_RS15845	COG2197	response regulator
SRIM_RS15850	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SRIM_RS15860	COG0823	Involved in the tonB-independent uptake of proteins
SRIM_RS15865	COG5002	protein histidine kinase activity
SRIM_RS15865	COG5000	phosphorelay sensor kinase activity
SRIM_RS15870	COG0745	RESPONSE REGULATOR receiver
SRIM_RS15875	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SRIM_RS15895	COG0714	Associated with various cellular activities
SRIM_RS15935	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SRIM_RS15955	COG1482	cell wall glycoprotein biosynthetic process
SRIM_RS15965	COG2835	tetraacyldisaccharide 4'-kinase activity
SRIM_RS15970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SRIM_RS15975	COG1620	l-lactate permease
SRIM_RS16010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SRIM_RS16015	COG0778	Nitroreductase
SRIM_RS16015	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SRIM_RS16060	COG0477	Major facilitator Superfamily
SRIM_RS16080	COG1607	acyl-coa hydrolase
SRIM_RS16085	COG1316	TRANSCRIPTIONal
SRIM_RS16115	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SRIM_RS16150	COG5002	protein histidine kinase activity
SRIM_RS16155	COG0745	RESPONSE REGULATOR receiver
SRIM_RS16160	COG3104	oligopeptide transport
SRIM_RS16190	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIM_RS16195	COG1191	sigma factor activity
SRIM_RS16200	COG3963	phosphatidate phosphatase activity
SRIM_RS16210	COG2197	response regulator
SRIM_RS16220	COG1228	amidohydrolase
SRIM_RS16225	COG0402	S-adenosylhomocysteine deaminase activity
SRIM_RS16230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIM_RS16235	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SRIM_RS16245	COG3938	Belongs to the proline racemase family
SRIM_RS16260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIM_RS16260	COG2022	thiamine diphosphate biosynthetic process
SRIM_RS16265	COG0019	diaminopimelate decarboxylase activity
SRIM_RS16290	COG0596	Alpha beta hydrolase
SRIM_RS16305	COG1609	Transcriptional regulator
SRIM_RS16320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SRIM_RS16335	COG2755	lipolytic protein G-D-S-L family
SRIM_RS16340	COG0183	Belongs to the thiolase family
SRIM_RS16410	COG1136	(ABC) transporter
SRIM_RS16415	COG0577	efflux transmembrane transporter activity
SRIM_RS16420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SRIM_RS16445	COG0148	phosphopyruvate hydratase activity
SRIM_RS16460	COG2124	cytochrome p450
SRIM_RS16470	COG0583	DNA-binding transcription factor activity
SRIM_RS16475	COG2814	Major facilitator Superfamily
SRIM_RS16500	COG3896	Chloramphenicol phosphotransferase-like protein
SRIM_RS16515	COG2814	Major facilitator Superfamily
SRIM_RS16525	COG1316	TRANSCRIPTIONal
SRIM_RS16550	COG4585	Histidine kinase
SRIM_RS16565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SRIM_RS16570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SRIM_RS16575	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SRIM_RS16580	COG0193	aminoacyl-tRNA hydrolase activity
SRIM_RS16595	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SRIM_RS16605	COG1309	transcriptional regulator
SRIM_RS16615	COG4106	trans-aconitate 2-methyltransferase activity
SRIM_RS16635	COG2197	response regulator
SRIM_RS16640	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SRIM_RS16670	COG0488	(ABC) transporter
SRIM_RS16680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SRIM_RS16685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SRIM_RS16690	COG3584	3D domain protein
SRIM_RS16690	COG3583	domain protein
SRIM_RS16695	COG0084	hydrolase, TatD family'
SRIM_RS16720	COG0768	penicillin binding
SRIM_RS16730	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS16740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRIM_RS16745	COG1122	ATPase activity
SRIM_RS16755	COG0310	cobalt ion transport
SRIM_RS16770	COG2409	Drug exporters of the RND superfamily
SRIM_RS16780	COG0793	Belongs to the peptidase S41A family
SRIM_RS16780	COG4946	Tricorn protease homolog
SRIM_RS16795	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS16800	COG2267	carboxylic ester hydrolase activity
SRIM_RS16805	COG2072	flavoprotein involved in K transport
SRIM_RS16815	COG1335	isochorismatase
SRIM_RS16820	COG0251	oxidation-reduction process
SRIM_RS16825	COG1733	regulation of RNA biosynthetic process
SRIM_RS16890	COG0708	Exodeoxyribonuclease III
SRIM_RS16910	COG2205	protein histidine kinase activity
SRIM_RS16920	COG0789	Transcriptional regulator
SRIM_RS16925	COG1819	glycosyl
SRIM_RS16945	COG0395	ABC-type sugar transport system, permease component
SRIM_RS16950	COG1175	transmembrane transport
SRIM_RS16960	COG1609	Transcriptional regulator
SRIM_RS16965	COG0739	heme binding
SRIM_RS16985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SRIM_RS16990	COG0521	Mo-molybdopterin cofactor biosynthetic process
SRIM_RS16995	COG0315	cyclic pyranopterin monophosphate synthase activity
SRIM_RS17005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SRIM_RS17010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SRIM_RS17015	COG2366	antibiotic biosynthetic process
SRIM_RS17020	COG3263	regulation of cellular component size
SRIM_RS17025	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SRIM_RS17035	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SRIM_RS17040	COG1970	mechanosensitive ion channel activity
SRIM_RS17065	COG0477	Major facilitator Superfamily
SRIM_RS17070	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SRIM_RS17075	COG2188	Transcriptional regulator
SRIM_RS17080	COG0730	response to heat
SRIM_RS17105	COG1473	amidohydrolase
SRIM_RS17120	COG3191	aminopeptidase activity
SRIM_RS17135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIM_RS17155	COG1349	DNA-binding transcription factor activity
SRIM_RS17165	COG1247	-acetyltransferase
SRIM_RS17185	COG1846	Transcriptional regulator
SRIM_RS17215	COG1309	transcriptional regulator
SRIM_RS17285	COG0477	Major facilitator Superfamily
SRIM_RS17300	COG0659	secondary active sulfate transmembrane transporter activity
SRIM_RS17390	COG5280	Phage tail tape measure protein TP901
SRIM_RS17390	COG3953	SLT domain
SRIM_RS17575	COG1674	ftsk spoiiie
SRIM_RS17820	COG1595	DNA-templated transcription, initiation
SRIM_RS17840	COG0514	ATP-dependent DNA helicase (RecQ)
SRIM_RS17870	COG2205	protein histidine kinase activity
SRIM_RS17895	COG0640	Transcriptional regulator
SRIM_RS17905	COG1686	Belongs to the peptidase S11 family
SRIM_RS17930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIM_RS17985	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SRIM_RS18025	COG0492	ferredoxin-NADP+ reductase activity
SRIM_RS18045	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SRIM_RS18120	COG1024	Enoyl-CoA hydratase
SRIM_RS18140	COG0515	serine threonine protein kinase
SRIM_RS18140	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SRIM_RS18150	COG1309	transcriptional regulator
SRIM_RS18160	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS18265	COG2072	flavoprotein involved in K transport
SRIM_RS18275	COG1024	Enoyl-CoA hydratase
SRIM_RS18280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SRIM_RS18290	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS18295	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS18310	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS18315	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS18325	COG0583	DNA-binding transcription factor activity
SRIM_RS18330	COG0477	Major facilitator Superfamily
SRIM_RS18350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SRIM_RS18365	COG0516	GMP reductase activity
SRIM_RS18380	COG1595	DNA-templated transcription, initiation
SRIM_RS18385	COG2197	response regulator
SRIM_RS18395	COG0583	DNA-binding transcription factor activity
SRIM_RS18405	COG4221	oxidoreductase activity
SRIM_RS18415	COG1609	Transcriptional regulator
SRIM_RS18440	COG0459	protein refolding
SRIM_RS18445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SRIM_RS18450	COG0745	RESPONSE REGULATOR receiver
SRIM_RS18455	COG2205	protein histidine kinase activity
SRIM_RS18460	COG1316	TRANSCRIPTIONal
SRIM_RS18465	COG0772	Belongs to the SEDS family
SRIM_RS18485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SRIM_RS18510	COG0802	atpase or kinase
SRIM_RS18520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SRIM_RS18530	COG0736	holo-[acyl-carrier-protein] synthase activity
SRIM_RS18535	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SRIM_RS18540	COG1072	(Pantothenic acid kinase))
SRIM_RS18550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SRIM_RS18555	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SRIM_RS18560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SRIM_RS18570	COG0488	(ABC) transporter
SRIM_RS18580	COG0101	tRNA pseudouridine synthase activity
SRIM_RS18585	COG0203	ribosomal protein L17
SRIM_RS18590	COG0202	RNA polymerase activity
SRIM_RS18595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SRIM_RS18600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SRIM_RS18605	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SRIM_RS18610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SRIM_RS18620	COG0563	adenylate kinase activity
SRIM_RS18630	COG0200	Binds to the 23S rRNA
SRIM_RS18635	COG1841	ribosomal large subunit assembly
SRIM_RS18640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SRIM_RS18645	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SRIM_RS18650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SRIM_RS18655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SRIM_RS18660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SRIM_RS18665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SRIM_RS18670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SRIM_RS18675	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SRIM_RS18680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SRIM_RS18685	COG0255	Belongs to the universal ribosomal protein uL29 family
SRIM_RS18690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SRIM_RS18695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SRIM_RS18700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SRIM_RS18705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SRIM_RS18710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SRIM_RS18715	COG0089	rRNA binding
SRIM_RS18720	COG0088	Forms part of the polypeptide exit tunnel
SRIM_RS18725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SRIM_RS18730	COG0051	transcription antitermination factor activity, RNA binding
SRIM_RS18755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SRIM_RS18760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SRIM_RS18765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SRIM_RS18770	COG0049	tRNA binding
SRIM_RS18775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SRIM_RS18785	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SRIM_RS18790	COG0085	RNA polymerase activity
SRIM_RS18795	COG0222	ribosome binding
SRIM_RS18800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SRIM_RS18810	COG0081	regulation of translation
SRIM_RS18815	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SRIM_RS18835	COG0436	Aminotransferase
SRIM_RS18840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SRIM_RS18845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SRIM_RS18855	COG2030	dehydratase
SRIM_RS18860	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SRIM_RS18880	COG0702	epimerase
SRIM_RS18890	COG1666	GTP binding
SRIM_RS18900	COG3304	Inner membrane component domain
SRIM_RS18905	COG0501	Belongs to the peptidase M48B family
SRIM_RS18910	COG1007	ATP synthesis coupled electron transport
SRIM_RS18920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SRIM_RS18925	COG0713	ATP synthesis coupled electron transport
SRIM_RS18930	COG0839	Belongs to the complex I subunit 6 family
SRIM_RS18935	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIM_RS18940	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SRIM_RS18945	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIM_RS18950	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIM_RS18955	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIM_RS18975	COG4585	Histidine kinase
SRIM_RS18980	COG4585	Histidine kinase
SRIM_RS18990	COG0674	pyruvate-flavodoxin oxidoreductase activity
SRIM_RS18990	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SRIM_RS18995	COG1013	pyruvate-flavodoxin oxidoreductase activity
SRIM_RS19005	COG2234	aminopeptidase activity
SRIM_RS19005	COG4935	Belongs to the peptidase S8 family
SRIM_RS19025	COG0142	geranyltranstransferase activity
SRIM_RS19030	COG0492	ferredoxin-NADP+ reductase activity
SRIM_RS19060	COG1007	ATP synthesis coupled electron transport
SRIM_RS19070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SRIM_RS19075	COG0713	ATP synthesis coupled electron transport
SRIM_RS19080	COG0839	Belongs to the complex I subunit 6 family
SRIM_RS19085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIM_RS19090	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SRIM_RS19095	COG1034	ATP synthesis coupled electron transport
SRIM_RS19100	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SRIM_RS19110	COG0649	NAD binding
SRIM_RS19115	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIM_RS19120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIM_RS19160	COG2226	methyltransferase
SRIM_RS19175	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SRIM_RS19185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SRIM_RS19190	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SRIM_RS19195	COG1278	Cold shock
SRIM_RS19220	COG1309	transcriptional regulator
SRIM_RS19235	COG1823	symporter activity
SRIM_RS19250	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SRIM_RS19265	COG0163	prenyltransferase activity
SRIM_RS19280	COG0109	protoheme IX farnesyltransferase activity
SRIM_RS19285	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SRIM_RS19330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SRIM_RS19335	COG1333	cytochrome c biogenesis protein
SRIM_RS19340	COG0785	Cytochrome C biogenesis protein
SRIM_RS19355	COG0406	alpha-ribazole phosphatase activity
SRIM_RS19360	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SRIM_RS19370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRIM_RS19385	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS19400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SRIM_RS19410	COG1742	UPF0060 membrane protein
SRIM_RS19430	COG1690	Belongs to the RtcB family
SRIM_RS19495	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SRIM_RS19500	COG0018	arginyl-trna synthetase
SRIM_RS19525	COG2814	Major facilitator Superfamily
SRIM_RS19560	COG0113	porphobilinogen synthase activity
SRIM_RS19565	COG1648	precorrin-2 dehydrogenase activity
SRIM_RS19565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SRIM_RS19570	COG0181	hydroxymethylbilane synthase activity
SRIM_RS19575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SRIM_RS19580	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SRIM_RS19635	COG0123	including yeast histone deacetylase and acetoin utilization protein
SRIM_RS19640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SRIM_RS19675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIM_RS19700	COG0579	oxidoreductase
SRIM_RS19705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SRIM_RS19740	COG0667	Aldo Keto reductase
SRIM_RS19745	COG2814	Major facilitator Superfamily
SRIM_RS19820	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SRIM_RS19870	COG0513	Belongs to the DEAD box helicase family
SRIM_RS19905	COG1643	Atp-dependent helicase
SRIM_RS19965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SRIM_RS19970	COG0047	phosphoribosylformylglycinamidine synthase activity
SRIM_RS19975	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SRIM_RS20010	COG3850	Histidine kinase
SRIM_RS20025	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SRIM_RS20030	COG2814	Major facilitator Superfamily
SRIM_RS20035	COG0583	DNA-binding transcription factor activity
SRIM_RS20050	COG0151	Belongs to the GarS family
SRIM_RS20065	COG1802	Transcriptional regulator
SRIM_RS20070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SRIM_RS20080	COG0693	protein deglycase activity
SRIM_RS20100	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SRIM_RS20125	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SRIM_RS20140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SRIM_RS20155	COG1131	(ABC) transporter
SRIM_RS20160	COG3559	Exporter of polyketide antibiotics
SRIM_RS20175	COG2197	response regulator
SRIM_RS20180	COG4585	Histidine kinase
SRIM_RS20185	COG0657	acetylesterase activity
SRIM_RS20190	COG3844	kynureninase activity
SRIM_RS20195	COG3483	tryptophan 2,3-dioxygenase activity
SRIM_RS20205	COG0191	fructose-bisphosphate aldolase activity
SRIM_RS20210	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SRIM_RS20225	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SRIM_RS20260	COG0542	response to heat
SRIM_RS20280	COG0789	Transcriptional regulator
SRIM_RS20285	COG0484	heat shock protein binding
SRIM_RS20290	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SRIM_RS20295	COG0443	Heat shock 70 kDa protein
SRIM_RS20300	COG2181	nitrate reductase activity
SRIM_RS20300	COG0247	lactate metabolic process
SRIM_RS20335	COG0717	Belongs to the dCTP deaminase family
SRIM_RS20390	COG5635	Nacht domain
SRIM_RS20390	COG2319	Wd-40 repeat
SRIM_RS20415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS20415	COG3321	synthase
SRIM_RS20430	COG0789	Transcriptional regulator
SRIM_RS20445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SRIM_RS20455	COG3629	intracellular signal transduction
SRIM_RS20475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS20485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIM_RS20495	COG2197	response regulator
SRIM_RS20510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIM_RS20525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIM_RS20545	COG0477	Major facilitator Superfamily
SRIM_RS20585	COG1316	TRANSCRIPTIONal
SRIM_RS20675	COG1125	glycine betaine transport
SRIM_RS20675	COG0517	IMP dehydrogenase activity
SRIM_RS20685	COG1174	glycine betaine transport
SRIM_RS20690	COG1174	glycine betaine transport
SRIM_RS20715	COG2226	methyltransferase
SRIM_RS20720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SRIM_RS20735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SRIM_RS20745	COG0628	permease
SRIM_RS20750	COG1741	Belongs to the pirin family
SRIM_RS20765	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS20770	COG1362	aminopeptidase activity
SRIM_RS20775	COG3629	intracellular signal transduction
SRIM_RS20775	COG3903	Transcriptional regulator
SRIM_RS20790	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIM_RS20855	COG1802	Transcriptional regulator
SRIM_RS20880	COG0477	Major facilitator Superfamily
SRIM_RS20935	COG0508	dehydrogenase complex catalyzes the overall conversion of
SRIM_RS20940	COG0022	dehydrogenase e1 component
SRIM_RS20965	COG0515	serine threonine protein kinase
SRIM_RS20970	COG0515	serine threonine protein kinase
SRIM_RS20985	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS20985	COG3321	synthase
SRIM_RS20985	COG0604	alcohol dehydrogenase
SRIM_RS20990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SRIM_RS20995	COG0303	'Molybdopterin
SRIM_RS21000	COG0746	molybdenum cofactor guanylyltransferase activity
SRIM_RS21020	COG1522	sequence-specific DNA binding
SRIM_RS21025	COG1309	transcriptional regulator
SRIM_RS21030	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIM_RS21055	COG3396	Phenylacetate-CoA oxygenase
SRIM_RS21060	COG3460	Phenylacetate-CoA oxygenase
SRIM_RS21065	COG3396	Phenylacetate-CoA oxygenase
SRIM_RS21070	COG2151	metal-sulfur cluster biosynthetic enzyme
SRIM_RS21075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SRIM_RS21110	COG1733	regulation of RNA biosynthetic process
SRIM_RS21115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SRIM_RS21120	COG2197	response regulator
SRIM_RS21125	COG4585	Histidine kinase
SRIM_RS21135	COG0583	DNA-binding transcription factor activity
SRIM_RS21145	COG1716	ATPase activity
SRIM_RS21150	COG1716	ATPase activity
SRIM_RS21165	COG0768	penicillin binding
SRIM_RS21170	COG0515	serine threonine protein kinase
SRIM_RS21175	COG3764	Sortase (surface protein transpeptidase)
SRIM_RS21180	COG3764	Sortase (surface protein transpeptidase)
SRIM_RS21195	COG3764	Sortase (surface protein transpeptidase)
SRIM_RS21210	COG0705	Rhomboid family
SRIM_RS21235	COG0515	serine threonine protein kinase
SRIM_RS21260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SRIM_RS21270	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SRIM_RS21275	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SRIM_RS21280	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SRIM_RS21285	COG0592	DNA-directed DNA polymerase activity
SRIM_RS21290	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SRIM_RS21295	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SRIM_RS21305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SRIM_RS21310	COG0706	membrane insertase activity
SRIM_RS21320	COG0357	Ribosomal RNA small subunit methyltransferase G
SRIM_RS21325	COG1192	Involved in chromosome partitioning
SRIM_RS21340	COG3118	belongs to the thioredoxin family
SRIM_RS21345	COG0492	ferredoxin-NADP+ reductase activity
SRIM_RS21355	COG1595	DNA-templated transcription, initiation
SRIM_RS21380	COG0617	tRNA 3'-terminal CCA addition
SRIM_RS21400	COG1695	Transcriptional regulator
SRIM_RS21405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRIM_RS21430	COG0360	Binds together with S18 to 16S ribosomal RNA
SRIM_RS21435	COG0629	single-stranded DNA binding
SRIM_RS21440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SRIM_RS21445	COG0359	binds to the 23S rRNA
SRIM_RS21455	COG0534	Mate efflux family protein
SRIM_RS21460	COG0305	Participates in initiation and elongation during chromosome replication
SRIM_RS21475	COG1309	transcriptional regulator
SRIM_RS21480	COG0242	peptide deformylase activity
SRIM_RS21505	COG0789	Transcriptional regulator
SRIM_RS21505	COG4978	Transcriptional regulator
SRIM_RS21540	COG1846	Transcriptional regulator
SRIM_RS21545	COG2814	Major facilitator Superfamily
SRIM_RS21585	COG0626	cystathionine gamma-synthase activity
SRIM_RS21590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SRIM_RS21595	COG1950	PFAM Membrane protein of
SRIM_RS21600	COG0662	Cupin 2, conserved barrel domain protein
SRIM_RS21625	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SRIM_RS21645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SRIM_RS21650	COG1609	Transcriptional regulator
SRIM_RS21655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SRIM_RS21665	COG1271	oxidase subunit
SRIM_RS21670	COG1294	oxidase, subunit
SRIM_RS21675	COG4988	ABC transporter
SRIM_RS21685	COG0739	heme binding
SRIM_RS21690	COG0561	phosphatase activity
SRIM_RS21700	COG0501	Belongs to the peptidase M48B family
SRIM_RS21725	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SRIM_RS21740	COG0789	Transcriptional regulator
SRIM_RS21760	COG1131	(ABC) transporter
SRIM_RS21800	COG0789	Transcriptional regulator
SRIM_RS21810	COG2807	transmembrane transport
SRIM_RS21815	COG2186	Transcriptional regulator
SRIM_RS21830	COG0789	Transcriptional regulator
SRIM_RS21860	COG0561	phosphatase activity
SRIM_RS21865	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SRIM_RS21875	COG2837	iron assimilation
SRIM_RS21880	COG2372	response to copper ion
SRIM_RS21915	COG0006	proline dipeptidase activity
SRIM_RS21955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRIM_RS22090	COG2188	Transcriptional regulator
SRIM_RS22115	COG0457	Tetratricopeptide repeat
SRIM_RS22150	COG1595	DNA-templated transcription, initiation
SRIM_RS22205	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS22245	COG2249	NAD(P)H dehydrogenase (quinone) activity
SRIM_RS22270	COG0745	RESPONSE REGULATOR receiver
SRIM_RS22275	COG2205	protein histidine kinase activity
SRIM_RS22285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SRIM_RS22290	COG0477	Major facilitator Superfamily
SRIM_RS22330	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIM_RS22340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SRIM_RS22390	COG0110	maltose O-acetyltransferase activity
SRIM_RS22425	COG1595	DNA-templated transcription, initiation
SRIM_RS22445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIM_RS22455	COG1191	sigma factor activity
SRIM_RS22460	COG1191	sigma factor activity
SRIM_RS22475	COG0640	Transcriptional regulator
SRIM_RS22515	COG0657	acetylesterase activity
SRIM_RS22540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SRIM_RS22575	COG0523	cobalamin synthesis protein
SRIM_RS22610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SRIM_RS22615	COG1940	carbohydrate kinase activity
SRIM_RS22625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIM_RS22645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRIM_RS22655	COG0463	Glycosyl transferase, family 2
SRIM_RS22660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SRIM_RS22665	COG4552	Acetyltransferase involved in intracellular survival and related
SRIM_RS22680	COG0488	(ABC) transporter
SRIM_RS22695	COG1309	transcriptional regulator
SRIM_RS22705	COG1609	Transcriptional regulator
SRIM_RS22710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SRIM_RS22715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SRIM_RS22720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SRIM_RS22750	COG0402	S-adenosylhomocysteine deaminase activity
SRIM_RS22770	COG1595	DNA-templated transcription, initiation
SRIM_RS22775	COG2249	NAD(P)H dehydrogenase (quinone) activity
SRIM_RS22810	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SRIM_RS22815	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SRIM_RS22835	COG1595	DNA-templated transcription, initiation
SRIM_RS22850	COG1357	PFAM Pentapeptide repeats (8 copies)
SRIM_RS22955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIM_RS22965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIM_RS22970	COG0515	serine threonine protein kinase
SRIM_RS22990	COG2030	dehydratase
SRIM_RS22995	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS23000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIM_RS23010	COG1819	glycosyl
SRIM_RS23020	COG4106	trans-aconitate 2-methyltransferase activity
SRIM_RS23070	COG1408	metallophosphoesterase
SRIM_RS23080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRIM_RS23090	COG0003	Pfam Anion-transporting ATPase
SRIM_RS23115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SRIM_RS23125	COG2957	Belongs to the agmatine deiminase family
SRIM_RS23150	COG2267	carboxylic ester hydrolase activity
SRIM_RS23160	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SRIM_RS23165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SRIM_RS23230	COG1917	Cupin 2, conserved barrel domain protein
SRIM_RS23240	COG1111	helicase
SRIM_RS23240	COG1205	dead DEAH box helicase
SRIM_RS23245	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIM_RS23255	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SRIM_RS23265	COG2890	protein-(glutamine-N5) methyltransferase activity
SRIM_RS23285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SRIM_RS23285	COG1754	DNA topoisomerase type I activity
SRIM_RS23295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SRIM_RS23300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SRIM_RS23315	COG2366	antibiotic biosynthetic process
SRIM_RS23320	COG1132	(ABC) transporter
SRIM_RS23335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS23350	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
SRIM_RS23360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SRIM_RS23385	COG0584	glycerophosphoryl diester phosphodiesterase
SRIM_RS23390	COG2197	response regulator
SRIM_RS23425	COG1349	DNA-binding transcription factor activity
SRIM_RS23435	COG1309	transcriptional regulator
SRIM_RS23440	COG0657	acetylesterase activity
SRIM_RS23445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SRIM_RS23445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SRIM_RS23450	COG3655	Transcriptional regulator
SRIM_RS23465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SRIM_RS23465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SRIM_RS23475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SRIM_RS23480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SRIM_RS23490	COG0254	rRNA binding
SRIM_RS23500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SRIM_RS23520	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS23525	COG2318	DinB family
SRIM_RS23545	COG0076	glutamate decarboxylase activity
SRIM_RS23550	COG0655	NAD(P)H dehydrogenase (quinone) activity
SRIM_RS23590	COG0789	Transcriptional regulator
SRIM_RS23595	COG0393	Putative heavy-metal-binding
SRIM_RS23610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SRIM_RS23615	COG2027	D-alanyl-D-alanine carboxypeptidase
SRIM_RS23625	COG0037	tRNA processing
SRIM_RS23640	COG0302	gtp cyclohydrolase
SRIM_RS23650	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SRIM_RS23650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SRIM_RS23665	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SRIM_RS23670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SRIM_RS23680	COG0517	IMP dehydrogenase activity
SRIM_RS23680	COG1125	glycine betaine transport
SRIM_RS23685	COG1174	glycine betaine transport
SRIM_RS23690	COG1174	glycine betaine transport
SRIM_RS23695	COG1732	Glycine betaine
SRIM_RS23705	COG2814	Major facilitator Superfamily
SRIM_RS23710	COG1309	transcriptional regulator
SRIM_RS23720	COG3226	Transcriptional regulator
SRIM_RS23735	COG0649	NAD binding
SRIM_RS23765	COG0640	Transcriptional regulator
SRIM_RS23780	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SRIM_RS23785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SRIM_RS23795	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SRIM_RS23815	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SRIM_RS23840	COG0739	heme binding
SRIM_RS23840	COG0741	lytic transglycosylase activity
SRIM_RS23840	COG1196	nuclear chromosome segregation
SRIM_RS23855	COG2207	Transcriptional regulator
SRIM_RS23855	COG4753	response regulator
SRIM_RS23860	COG0346	lactoylglutathione lyase activity
SRIM_RS23865	COG2205	protein histidine kinase activity
SRIM_RS23870	COG0745	RESPONSE REGULATOR receiver
SRIM_RS23880	COG1595	DNA-templated transcription, initiation
SRIM_RS23885	COG1194	a g-specific adenine glycosylase
SRIM_RS23895	COG0671	phosphoesterase, PA-phosphatase related
SRIM_RS23910	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SRIM_RS23930	COG0248	Ppx GppA phosphatase
SRIM_RS23935	COG1082	Xylose isomerase domain protein TIM barrel
SRIM_RS23945	COG0129	dihydroxy-acid dehydratase activity
SRIM_RS23975	COG2226	methyltransferase
SRIM_RS23980	COG0308	aminopeptidase N
SRIM_RS23985	COG0659	secondary active sulfate transmembrane transporter activity
SRIM_RS24005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SRIM_RS24010	COG0180	Tryptophanyl-tRNA synthetase
SRIM_RS24090	COG0791	NLP P60 protein
SRIM_RS24095	COG0671	phosphoesterase, PA-phosphatase related
SRIM_RS24105	COG0277	FAD linked oxidase domain protein
SRIM_RS24125	COG1937	Protein conserved in bacteria
SRIM_RS24135	COG0306	phosphate transporter
SRIM_RS24155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SRIM_RS24190	COG0604	alcohol dehydrogenase
SRIM_RS24195	COG1733	regulation of RNA biosynthetic process
SRIM_RS24205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SRIM_RS24225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SRIM_RS24235	COG2890	protein-(glutamine-N5) methyltransferase activity
SRIM_RS24250	COG1733	regulation of RNA biosynthetic process
SRIM_RS24265	COG4552	Acetyltransferase involved in intracellular survival and related
SRIM_RS24280	COG1490	D-aminoacyl-tRNA deacylase activity
SRIM_RS24285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SRIM_RS24290	COG0735	belongs to the Fur family
SRIM_RS24300	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SRIM_RS24305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS24310	COG3485	protocatechuate 3,4-dioxygenase
SRIM_RS24330	COG2897	thiosulfate sulfurtransferase activity
SRIM_RS24365	COG0745	RESPONSE REGULATOR receiver
SRIM_RS24370	COG1609	Transcriptional regulator
SRIM_RS24375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRIM_RS24385	COG0745	RESPONSE REGULATOR receiver
SRIM_RS24400	COG0702	epimerase
SRIM_RS24445	COG0737	Belongs to the 5'-nucleotidase family
SRIM_RS24450	COG0456	acetyltransferase
SRIM_RS24470	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SRIM_RS24490	COG0667	Aldo Keto reductase
SRIM_RS24505	COG0438	transferase activity, transferring glycosyl groups
SRIM_RS24520	COG0588	phosphoglycerate mutase activity
SRIM_RS24525	COG0367	asparagine synthase
SRIM_RS24545	COG5002	protein histidine kinase activity
SRIM_RS24560	COG1329	Transcriptional regulator
SRIM_RS24565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SRIM_RS24570	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SRIM_RS24575	COG3467	pyridoxamine 5'-phosphate
SRIM_RS24580	COG0215	cysteine-tRNA ligase activity
SRIM_RS24595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SRIM_RS24605	COG3842	ATPase activity
SRIM_RS24620	COG2207	Transcriptional regulator
SRIM_RS24620	COG3708	Transcriptional regulator
SRIM_RS24670	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SRIM_RS24695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SRIM_RS24700	COG1940	carbohydrate kinase activity
SRIM_RS24725	COG0463	Glycosyl transferase, family 2
SRIM_RS24740	COG1278	Cold shock
SRIM_RS24750	COG4221	oxidoreductase activity
SRIM_RS24755	COG1115	amino acid carrier protein
SRIM_RS24765	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SRIM_RS24770	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SRIM_RS24805	COG3142	Participates in the control of copper homeostasis
SRIM_RS24810	COG3973	AAA domain
SRIM_RS24825	COG1061	Type III restriction enzyme res subunit
SRIM_RS24845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SRIM_RS24850	COG1120	ATPase activity
SRIM_RS24855	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS24860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS24875	COG1278	Cold shock
SRIM_RS24880	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SRIM_RS24885	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SRIM_RS24895	COG2814	Major facilitator Superfamily
SRIM_RS24915	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SRIM_RS24925	COG2252	PERMEase
SRIM_RS24950	COG0667	Aldo Keto reductase
SRIM_RS24960	COG0667	Aldo Keto reductase
SRIM_RS24995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SRIM_RS25000	COG2378	regulation of single-species biofilm formation
SRIM_RS25010	COG0277	FAD linked oxidase domain protein
SRIM_RS25010	COG0247	lactate metabolic process
SRIM_RS25015	COG0583	DNA-binding transcription factor activity
SRIM_RS25020	COG5006	permease, DMT superfamily
SRIM_RS25030	COG2124	cytochrome p450
SRIM_RS25065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SRIM_RS25080	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS25085	COG1024	Enoyl-CoA hydratase
SRIM_RS25090	COG1309	transcriptional regulator
SRIM_RS25110	COG0259	pyridoxamine-phosphate oxidase activity
SRIM_RS25120	COG4821	SIS domain
SRIM_RS25150	COG1131	(ABC) transporter
SRIM_RS25200	COG4585	Histidine kinase
SRIM_RS25205	COG2197	response regulator
SRIM_RS25220	COG0515	serine threonine protein kinase
SRIM_RS25225	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS25245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SRIM_RS25245	COG0519	Catalyzes the synthesis of GMP from XMP
SRIM_RS25260	COG2084	Dehydrogenase
SRIM_RS25305	COG0515	serine threonine protein kinase
SRIM_RS25305	COG2815	serine threonine protein kinase
SRIM_RS25320	COG2197	response regulator
SRIM_RS25330	COG1309	transcriptional regulator
SRIM_RS25360	COG0789	Transcriptional regulator
SRIM_RS25385	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS25430	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SRIM_RS25445	COG0714	Associated with various cellular activities
SRIM_RS25450	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SRIM_RS25455	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SRIM_RS25470	COG0045	succinate-CoA ligase (ADP-forming) activity
SRIM_RS25500	COG0138	bifunctional purine biosynthesis protein purh
SRIM_RS25510	COG1714	RDD family
SRIM_RS25515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SRIM_RS25550	COG0039	L-malate dehydrogenase activity
SRIM_RS25575	COG1476	TRANSCRIPTIONal
SRIM_RS25600	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS25610	COG0517	IMP dehydrogenase activity
SRIM_RS25610	COG4175	Glycine betaine
SRIM_RS25620	COG4176	ABC-type proline glycine betaine transport system permease component
SRIM_RS25630	COG4585	Histidine kinase
SRIM_RS25645	COG2197	response regulator
SRIM_RS25660	COG1396	sequence-specific DNA binding
SRIM_RS25670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIM_RS25675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIM_RS25700	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIM_RS25705	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIM_RS25710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIM_RS25725	COG0754	glutathionylspermidine amidase activity
SRIM_RS25730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRIM_RS25735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SRIM_RS25745	COG0180	Tryptophanyl-tRNA synthetase
SRIM_RS25770	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SRIM_RS25775	COG1295	ribonuclease BN
SRIM_RS25795	COG1404	Belongs to the peptidase S8 family
SRIM_RS25805	COG1309	transcriptional regulator
SRIM_RS25825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SRIM_RS25830	COG1053	succinate dehydrogenase
SRIM_RS25840	COG2009	succinate dehydrogenase
SRIM_RS25850	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SRIM_RS25875	COG1846	Transcriptional regulator
SRIM_RS25880	COG3961	Belongs to the TPP enzyme family
SRIM_RS25905	COG2186	Transcriptional regulator
SRIM_RS25910	COG3265	gluconokinase activity
SRIM_RS25945	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SRIM_RS25955	COG1216	Glycosyl transferase, family 2
SRIM_RS25965	COG1083	cytidylyl-transferase
SRIM_RS25970	COG2089	acid synthase
SRIM_RS25980	COG1473	amidohydrolase
SRIM_RS25980	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SRIM_RS25985	COG1744	ABC transporter substrate-binding protein PnrA-like
SRIM_RS25990	COG3845	ABC transporter
SRIM_RS25995	COG4603	Belongs to the binding-protein-dependent transport system permease family
SRIM_RS26000	COG1079	Belongs to the binding-protein-dependent transport system permease family
SRIM_RS26030	COG2814	Major facilitator Superfamily
SRIM_RS26035	COG0583	DNA-binding transcription factor activity
SRIM_RS26050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SRIM_RS26080	COG0745	RESPONSE REGULATOR receiver
SRIM_RS26085	COG1595	DNA-templated transcription, initiation
SRIM_RS26100	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS26105	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS26140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SRIM_RS26175	COG0702	epimerase
SRIM_RS26180	COG4770	biotin carboxylase activity
SRIM_RS26220	COG0424	maF-like protein
SRIM_RS26225	COG0768	penicillin binding
SRIM_RS26240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SRIM_RS26250	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SRIM_RS26255	COG1024	Enoyl-CoA hydratase
SRIM_RS26265	COG2986	histidine ammonia-lyase
SRIM_RS26320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SRIM_RS26340	COG1595	DNA-templated transcription, initiation
SRIM_RS26345	COG2255	four-way junction helicase activity
SRIM_RS26350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SRIM_RS26365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SRIM_RS26375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SRIM_RS26395	COG1331	Highly conserved protein containing a thioredoxin domain
SRIM_RS26405	COG0789	Transcriptional regulator
SRIM_RS26420	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SRIM_RS26440	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SRIM_RS26455	COG1414	Transcriptional regulator
SRIM_RS26460	COG0251	oxidation-reduction process
SRIM_RS26465	COG2610	gluconate transmembrane transporter activity
SRIM_RS26520	COG2894	cell division
SRIM_RS26565	COG2885	chlorophyll binding
SRIM_RS26610	COG0667	Aldo Keto reductase
SRIM_RS26615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SRIM_RS26620	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SRIM_RS26640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIM_RS26645	COG0450	alkyl hydroperoxide reductase
SRIM_RS26670	COG1136	(ABC) transporter
SRIM_RS26685	COG1136	(ABC) transporter
SRIM_RS26700	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SRIM_RS26725	COG0114	fumarate hydratase activity
SRIM_RS26730	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SRIM_RS26730	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SRIM_RS26755	COG0778	Nitroreductase
SRIM_RS26760	COG1722	exodeoxyribonuclease VII activity
SRIM_RS26765	COG1570	exodeoxyribonuclease VII activity
SRIM_RS26775	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SRIM_RS26790	COG0012	GTP binding
SRIM_RS26820	COG0596	Alpha beta hydrolase
SRIM_RS26820	COG0508	dehydrogenase complex catalyzes the overall conversion of
SRIM_RS26835	COG0531	amino acid
SRIM_RS26865	COG1053	succinate dehydrogenase
SRIM_RS26885	COG1217	gtp-binding protein TYPA
SRIM_RS26890	COG4166	transmembrane transport
SRIM_RS26895	COG0601	transmembrane transport
SRIM_RS26900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIM_RS26905	COG0444	Belongs to the ABC transporter superfamily
SRIM_RS26910	COG4608	Belongs to the ABC transporter superfamily
SRIM_RS26940	COG0601	transmembrane transport
SRIM_RS26945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIM_RS26955	COG4608	Belongs to the ABC transporter superfamily
SRIM_RS26965	COG4608	Belongs to the ABC transporter superfamily
SRIM_RS26970	COG0444	Belongs to the ABC transporter superfamily
SRIM_RS26980	COG4166	transmembrane transport
SRIM_RS26985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIM_RS27005	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SRIM_RS27025	COG1131	(ABC) transporter
SRIM_RS27035	COG4585	Histidine kinase
SRIM_RS27040	COG2197	response regulator
SRIM_RS27080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIM_RS27090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SRIM_RS27100	COG0519	Catalyzes the synthesis of GMP from XMP
SRIM_RS27105	COG1024	Enoyl-CoA hydratase
SRIM_RS27120	COG1595	DNA-templated transcription, initiation
SRIM_RS27130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRIM_RS27135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SRIM_RS27170	COG0598	Magnesium transport protein CorA
SRIM_RS27180	COG2814	Major facilitator Superfamily
SRIM_RS27195	COG2095	MarC family integral membrane protein
SRIM_RS27205	COG1432	Conserved Protein
SRIM_RS27245	COG2267	carboxylic ester hydrolase activity
SRIM_RS27260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIM_RS27265	COG0601	transmembrane transport
SRIM_RS27270	COG4172	Belongs to the ABC transporter superfamily
SRIM_RS27315	COG0210	DNA helicase
SRIM_RS27320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIM_RS27370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SRIM_RS27425	COG3480	Lon protease (S16) C-terminal proteolytic domain
SRIM_RS27435	COG1615	UPF0182 protein
SRIM_RS27465	COG0753	catalase activity
SRIM_RS27475	COG0483	inositol monophosphate 1-phosphatase activity
SRIM_RS27485	COG2076	Multidrug Resistance protein
SRIM_RS27500	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SRIM_RS27510	COG2135	peptidase activity
SRIM_RS27520	COG1396	sequence-specific DNA binding
SRIM_RS27520	COG3800	Transcriptional regulator
SRIM_RS27525	COG1595	DNA-templated transcription, initiation
SRIM_RS27530	COG5662	AntiSigma factor
SRIM_RS27540	COG0242	peptide deformylase activity
SRIM_RS27545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRIM_RS27550	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SRIM_RS27590	COG1966	Carbon starvation protein
SRIM_RS27595	COG2188	Transcriptional regulator
SRIM_RS27600	COG2182	Extracellular solute-binding protein
SRIM_RS27605	COG1175	transmembrane transport
SRIM_RS27610	COG0395	ABC-type sugar transport system, permease component
SRIM_RS27615	COG1472	Belongs to the glycosyl hydrolase 3 family
SRIM_RS27620	COG0363	glucosamine-6-phosphate deaminase activity
SRIM_RS27625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SRIM_RS27635	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS27640	COG1309	transcriptional regulator
SRIM_RS27655	COG1597	lipid kinase activity
SRIM_RS27710	COG2066	Belongs to the glutaminase family
SRIM_RS27725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIM_RS27740	COG0477	Major facilitator Superfamily
SRIM_RS27755	COG0598	Magnesium transport protein CorA
SRIM_RS27760	COG2807	transmembrane transport
SRIM_RS27765	COG2186	Transcriptional regulator
SRIM_RS27770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SRIM_RS27775	COG1993	acr, cog1993
SRIM_RS27780	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SRIM_RS27810	COG3629	intracellular signal transduction
SRIM_RS27810	COG3903	Transcriptional regulator
SRIM_RS27845	COG2201	protein-glutamate methylesterase activity
SRIM_RS27865	COG4106	trans-aconitate 2-methyltransferase activity
SRIM_RS27870	COG1126	abc transporter atp-binding protein
SRIM_RS27875	COG0765	amino acid transport
SRIM_RS27880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRIM_RS27885	COG0281	malic enzyme
SRIM_RS27895	COG0604	alcohol dehydrogenase
SRIM_RS28000	COG0508	dehydrogenase complex catalyzes the overall conversion of
SRIM_RS28000	COG0567	Dehydrogenase, E1 component
SRIM_RS28005	COG2205	protein histidine kinase activity
SRIM_RS28010	COG0745	RESPONSE REGULATOR receiver
SRIM_RS28025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SRIM_RS28050	COG1309	transcriptional regulator
SRIM_RS28120	COG1119	ATPase activity
SRIM_RS28130	COG0768	penicillin binding
SRIM_RS28140	COG2124	cytochrome p450
SRIM_RS28180	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIM_RS28190	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS28220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS28245	COG0745	RESPONSE REGULATOR receiver
SRIM_RS28250	COG0018	arginyl-trna synthetase
SRIM_RS28255	COG0019	diaminopimelate decarboxylase activity
SRIM_RS28260	COG0460	homoserine dehydrogenase
SRIM_RS28265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SRIM_RS28270	COG0083	homoserine kinase activity
SRIM_RS28285	COG0254	rRNA binding
SRIM_RS28290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SRIM_RS28295	COG2890	protein-(glutamine-N5) methyltransferase activity
SRIM_RS28305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SRIM_RS28310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SRIM_RS28330	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SRIM_RS28335	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SRIM_RS28340	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SRIM_RS28345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SRIM_RS28350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SRIM_RS28355	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SRIM_RS28360	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SRIM_RS28375	COG2197	response regulator
SRIM_RS28380	COG3850	Histidine kinase
SRIM_RS28410	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIM_RS28425	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SRIM_RS28460	COG1131	(ABC) transporter
SRIM_RS28480	COG0183	Belongs to the thiolase family
SRIM_RS28500	COG0745	RESPONSE REGULATOR receiver
SRIM_RS28505	COG2205	protein histidine kinase activity
SRIM_RS28560	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SRIM_RS28560	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SRIM_RS28565	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SRIM_RS28585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SRIM_RS28590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SRIM_RS28645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SRIM_RS28650	COG0857	belongs to the CobB CobQ family
SRIM_RS28650	COG0280	phosphate acetyltransferase
SRIM_RS28655	COG0205	6-phosphofructokinase activity
SRIM_RS28680	COG0753	catalase activity
SRIM_RS28685	COG1295	ribonuclease BN
SRIM_RS28690	COG0577	efflux transmembrane transporter activity
SRIM_RS28700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SRIM_RS28710	COG2319	Wd-40 repeat
SRIM_RS28710	COG4249	Peptidase C14 caspase catalytic subunit p20
SRIM_RS28720	COG0395	ABC-type sugar transport system, permease component
SRIM_RS28725	COG1175	transmembrane transport
SRIM_RS28735	COG4565	transcriptional regulatory protein
SRIM_RS28740	COG3290	protein histidine kinase activity
SRIM_RS28745	COG1301	dicarboxylic acid transport
SRIM_RS28755	COG0477	Major facilitator Superfamily
SRIM_RS28770	COG0667	Aldo Keto reductase
SRIM_RS28775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SRIM_RS28785	COG0366	Alpha amylase catalytic
SRIM_RS28790	COG0366	Alpha amylase catalytic
SRIM_RS28800	COG0058	SHG alpha-glucan phosphorylase activity
SRIM_RS28825	COG2197	response regulator
SRIM_RS28840	COG2318	DinB family
SRIM_RS28845	COG1595	DNA-templated transcription, initiation
SRIM_RS28850	COG1252	NADH dehydrogenase
SRIM_RS28855	COG2272	Belongs to the type-B carboxylesterase lipase family
SRIM_RS28860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SRIM_RS28865	COG0477	Major facilitator Superfamily
SRIM_RS28870	COG1132	(ABC) transporter
SRIM_RS28875	COG1132	(ABC) transporter
SRIM_RS28885	COG1376	ErfK ybiS ycfS ynhG family protein
SRIM_RS28910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SRIM_RS28910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SRIM_RS28915	COG0785	Cytochrome C biogenesis protein
SRIM_RS28935	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SRIM_RS28975	COG1760	l-serine dehydratase
SRIM_RS28980	COG0531	amino acid
SRIM_RS28985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SRIM_RS28990	COG0509	glycine decarboxylation via glycine cleavage system
SRIM_RS28995	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SRIM_RS29020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIM_RS29025	COG0747	negative chemotaxis
SRIM_RS29030	COG0601	transmembrane transport
SRIM_RS29035	COG0444	Belongs to the ABC transporter superfamily
SRIM_RS29040	COG4608	Belongs to the ABC transporter superfamily
SRIM_RS29060	COG2860	membrane
SRIM_RS29085	COG3903	Transcriptional regulator
SRIM_RS29085	COG3629	intracellular signal transduction
SRIM_RS29110	COG0482	sulfurtransferase activity
SRIM_RS29115	COG0667	Aldo Keto reductase
SRIM_RS29130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SRIM_RS29140	COG4221	oxidoreductase activity
SRIM_RS29150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SRIM_RS29160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SRIM_RS29165	COG0154	amidase activity
SRIM_RS29175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SRIM_RS29215	COG3511	phospholipase C
SRIM_RS29220	COG2409	Drug exporters of the RND superfamily
SRIM_RS29235	COG2197	response regulator
SRIM_RS29245	COG2133	pyrroloquinoline quinone binding
SRIM_RS29250	COG0667	Aldo Keto reductase
SRIM_RS29270	COG0440	acetolactate synthase activity
SRIM_RS29275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SRIM_RS29295	COG3835	regulator
SRIM_RS29300	COG0506	proline dehydrogenase activity
SRIM_RS29305	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS29320	COG0473	3-isopropylmalate dehydrogenase activity
SRIM_RS29325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SRIM_RS29330	COG2957	Belongs to the agmatine deiminase family
SRIM_RS29335	COG1309	transcriptional regulator
SRIM_RS29345	COG0477	Major facilitator Superfamily
SRIM_RS29350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SRIM_RS29355	COG2353	YceI-like domain
SRIM_RS29360	COG5492	domain, Protein
SRIM_RS29365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SRIM_RS29380	COG2814	Major facilitator Superfamily
SRIM_RS29385	COG2376	Dihydroxyacetone kinase
SRIM_RS29400	COG2018	Roadblock/LC7 domain
SRIM_RS29420	COG2018	Roadblock/LC7 domain
SRIM_RS29435	COG0179	Fumarylacetoacetate (FAA) hydrolase
SRIM_RS29440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SRIM_RS29530	COG1414	Transcriptional regulator
SRIM_RS29535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SRIM_RS29540	COG0066	3-isopropylmalate dehydratase activity
SRIM_RS29550	COG0776	regulation of translation
SRIM_RS29560	COG1920	GTP binding
SRIM_RS29570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SRIM_RS29575	COG1181	Belongs to the D-alanine--D-alanine ligase family
SRIM_RS29595	COG0351	phosphomethylpyrimidine kinase
SRIM_RS29600	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SRIM_RS29605	COG1461	Dihydroxyacetone kinase
SRIM_RS29615	COG0742	ribosomal rna small subunit methyltransferase
SRIM_RS29620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SRIM_RS29635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SRIM_RS29640	COG0571	ribonuclease III activity
SRIM_RS29645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SRIM_RS29650	COG1733	regulation of RNA biosynthetic process
SRIM_RS29670	COG1254	Belongs to the acylphosphatase family
SRIM_RS29680	COG1196	nuclear chromosome segregation
SRIM_RS29685	COG0477	Major facilitator Superfamily
SRIM_RS29695	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SRIM_RS29730	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SRIM_RS29740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SRIM_RS29750	COG0626	cystathionine gamma-synthase activity
SRIM_RS29755	COG1735	metal-dependent hydrolase with the TIM-barrel fold
SRIM_RS29790	COG0228	four-way junction DNA binding
SRIM_RS29795	COG1837	Belongs to the UPF0109 family
SRIM_RS29800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SRIM_RS29805	COG0336	Belongs to the RNA methyltransferase TrmD family
SRIM_RS29810	COG0335	large ribosomal subunit rRNA binding
SRIM_RS29820	COG0681	Belongs to the peptidase S26 family
SRIM_RS29830	COG0681	Belongs to the peptidase S26 family
SRIM_RS29850	COG0792	nuclease activity
SRIM_RS29865	COG1191	sigma factor activity
SRIM_RS29880	COG0052	Belongs to the universal ribosomal protein uS2 family
SRIM_RS29885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SRIM_RS29890	COG0528	UMP kinase activity
SRIM_RS29895	COG0233	cytoplasmic translational termination
SRIM_RS29905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SRIM_RS29915	COG4208	sulfate ABC transporter
SRIM_RS29920	COG3842	ATPase activity
SRIM_RS29945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SRIM_RS29955	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS29980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SRIM_RS29995	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS30005	COG3842	ATPase activity
SRIM_RS30010	COG1176	ABC-type spermidine putrescine transport system, permease component I
SRIM_RS30015	COG1177	transmembrane transport
SRIM_RS30020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIM_RS30105	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS30110	COG4585	Histidine kinase
SRIM_RS30115	COG2197	response regulator
SRIM_RS30130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SRIM_RS30135	COG0750	zinc metalloprotease
SRIM_RS30140	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SRIM_RS30155	COG0442	prolyl-tRNA aminoacylation
SRIM_RS30160	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SRIM_RS30175	COG0779	Required for maturation of 30S ribosomal subunits
SRIM_RS30190	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SRIM_RS30200	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SRIM_RS30205	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SRIM_RS30215	COG0455	bacterial-type flagellum organization
SRIM_RS30335	COG1674	ftsk spoiiie
SRIM_RS30345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SRIM_RS30350	COG1185	polyribonucleotide nucleotidyltransferase activity
SRIM_RS30355	COG0612	Peptidase, M16
SRIM_RS30360	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SRIM_RS30380	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SRIM_RS30385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRIM_RS30390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SRIM_RS30420	COG2770	Histidine kinase
SRIM_RS30420	COG2208	phosphoserine phosphatase activity
SRIM_RS30425	COG3437	response regulator, receiver
SRIM_RS30425	COG3850	Histidine kinase
SRIM_RS30425	COG4999	Histidine kinase
SRIM_RS30425	COG2205	protein histidine kinase activity
SRIM_RS30435	COG1674	ftsk spoiiie
SRIM_RS30445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SRIM_RS30455	COG1546	Belongs to the CinA family
SRIM_RS30455	COG1058	Belongs to the CinA family
SRIM_RS30460	COG1396	sequence-specific DNA binding
SRIM_RS30465	COG0783	Belongs to the Dps family
SRIM_RS30470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIM_RS30485	COG0181	hydroxymethylbilane synthase activity
SRIM_RS30495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SRIM_RS30500	COG1201	RNA secondary structure unwinding
SRIM_RS30505	COG1917	Cupin 2, conserved barrel domain protein
SRIM_RS30505	COG2207	Transcriptional regulator
SRIM_RS30530	COG0628	permease
SRIM_RS30535	COG2409	Drug exporters of the RND superfamily
SRIM_RS30570	COG0765	amino acid transport
SRIM_RS30575	COG0765	amino acid transport
SRIM_RS30585	COG1126	abc transporter atp-binding protein
SRIM_RS30595	COG2205	protein histidine kinase activity
SRIM_RS30600	COG1278	Cold shock
SRIM_RS30615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SRIM_RS30635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SRIM_RS30645	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SRIM_RS30650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SRIM_RS30660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SRIM_RS30695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SRIM_RS30700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SRIM_RS30705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SRIM_RS30720	COG3226	Transcriptional regulator
SRIM_RS30725	COG0154	amidase activity
SRIM_RS30740	COG0488	(ABC) transporter
SRIM_RS30755	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SRIM_RS30770	COG0514	ATP-dependent DNA helicase (RecQ)
SRIM_RS30795	COG2186	Transcriptional regulator
SRIM_RS30800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SRIM_RS30815	COG0187	DNA topoisomerase II activity
SRIM_RS30825	COG4585	Histidine kinase
SRIM_RS30830	COG2197	response regulator
SRIM_RS30835	COG4565	transcriptional regulatory protein
SRIM_RS30840	COG3290	protein histidine kinase activity
SRIM_RS30860	COG0372	Belongs to the citrate synthase family
SRIM_RS30865	COG0372	Belongs to the citrate synthase family
SRIM_RS30875	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SRIM_RS30880	COG0612	Peptidase, M16
SRIM_RS30900	COG1802	Transcriptional regulator
SRIM_RS30905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SRIM_RS30925	COG1435	thymidine kinase activity
SRIM_RS30960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SRIM_RS30965	COG0483	inositol monophosphate 1-phosphatase activity
SRIM_RS30975	COG0745	RESPONSE REGULATOR receiver
SRIM_RS30980	COG2205	protein histidine kinase activity
SRIM_RS31005	COG0756	dUTP diphosphatase activity
SRIM_RS31020	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SRIM_RS31025	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SRIM_RS31030	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SRIM_RS31040	COG1136	(ABC) transporter
SRIM_RS31040	COG0577	efflux transmembrane transporter activity
SRIM_RS31075	COG0569	domain protein
SRIM_RS31105	COG0531	amino acid
SRIM_RS31110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SRIM_RS31125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS31130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS31150	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SRIM_RS31160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SRIM_RS31160	COG0512	Glutamine amidotransferase of anthranilate synthase
SRIM_RS31170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SRIM_RS31175	COG0134	indole-3-glycerol-phosphate synthase activity
SRIM_RS31180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SRIM_RS31185	COG1834	amidinotransferase
SRIM_RS31220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS31245	COG2197	response regulator
SRIM_RS31265	COG0066	3-isopropylmalate dehydratase activity
SRIM_RS31270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SRIM_RS31285	COG3842	ATPase activity
SRIM_RS31350	COG2124	cytochrome p450
SRIM_RS31380	COG2264	protein methyltransferase activity
SRIM_RS31395	COG1120	ATPase activity
SRIM_RS31400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SRIM_RS31410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS31420	COG2382	esterase
SRIM_RS31425	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS31430	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS31435	COG1169	isochorismate synthase
SRIM_RS31440	COG1021	2,3-dihydroxybenzoate-AMP ligase
SRIM_RS31445	COG3433	isochorismatase activity
SRIM_RS31445	COG1535	isochorismatase
SRIM_RS31450	COG3433	isochorismatase activity
SRIM_RS31450	COG1535	isochorismatase
SRIM_RS31470	COG0702	epimerase
SRIM_RS31480	COG0583	DNA-binding transcription factor activity
SRIM_RS31505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SRIM_RS31515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIM_RS31520	COG4948	Mandelate Racemase Muconate Lactonizing
SRIM_RS31535	COG0747	negative chemotaxis
SRIM_RS31540	COG0601	transmembrane transport
SRIM_RS31545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIM_RS31570	COG2201	protein-glutamate methylesterase activity
SRIM_RS31590	COG0583	DNA-binding transcription factor activity
SRIM_RS31595	COG2814	Major facilitator Superfamily
SRIM_RS31610	COG0156	8-amino-7-oxononanoate synthase activity
SRIM_RS31615	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS31620	COG2986	histidine ammonia-lyase
SRIM_RS31635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SRIM_RS31640	COG4638	Rieske (2fe-2S)
SRIM_RS31660	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SRIM_RS31675	COG0302	gtp cyclohydrolase
SRIM_RS31685	COG0598	Magnesium transport protein CorA
SRIM_RS31690	COG1799	cell septum assembly
SRIM_RS31730	COG2208	phosphoserine phosphatase activity
SRIM_RS31730	COG2770	Histidine kinase
SRIM_RS31745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SRIM_RS31785	COG2197	response regulator
SRIM_RS31855	COG2235	arginine
SRIM_RS31860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SRIM_RS31865	COG0531	amino acid
SRIM_RS31870	COG1024	Enoyl-CoA hydratase
SRIM_RS31895	COG0546	phosphoglycolate phosphatase activity
SRIM_RS31910	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS31930	COG1024	Enoyl-CoA hydratase
SRIM_RS31935	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS31960	COG1063	alcohol dehydrogenase
SRIM_RS31970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SRIM_RS31985	COG2223	nitrite transmembrane transporter activity
SRIM_RS32000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SRIM_RS32005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SRIM_RS32020	COG0596	Alpha beta hydrolase
SRIM_RS32035	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SRIM_RS32040	COG1120	ATPase activity
SRIM_RS32045	COG4106	trans-aconitate 2-methyltransferase activity
SRIM_RS32050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SRIM_RS32065	COG1653	transport
SRIM_RS32070	COG1175	transmembrane transport
SRIM_RS32085	COG4213	ABC transporter substrate-binding protein
SRIM_RS32095	COG4214	carbohydrate transport
SRIM_RS32100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SRIM_RS32105	COG0531	amino acid
SRIM_RS32120	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIM_RS32120	COG1024	Enoyl-CoA hydratase
SRIM_RS32125	COG0183	Belongs to the thiolase family
SRIM_RS32135	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SRIM_RS32150	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SRIM_RS32155	COG0446	pyridine nucleotide-disulphide oxidoreductase
SRIM_RS32170	COG0183	Belongs to the thiolase family
SRIM_RS32180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SRIM_RS32185	COG3253	May function as heme-dependent peroxidase
SRIM_RS32210	COG3220	belongs to the UPF0276 family
SRIM_RS32215	COG1280	lysine exporter protein (LysE YggA)
SRIM_RS32245	COG4152	abc transporter atp-binding protein
SRIM_RS32275	COG1136	(ABC) transporter
SRIM_RS32285	COG4585	Histidine kinase
SRIM_RS32290	COG2197	response regulator
SRIM_RS32295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SRIM_RS32300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SRIM_RS32305	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SRIM_RS32315	COG0693	protein deglycase activity
SRIM_RS32345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SRIM_RS32350	COG0583	DNA-binding transcription factor activity
SRIM_RS32355	COG2362	D-Aminopeptidase
SRIM_RS32430	COG1215	transferase activity, transferring glycosyl groups
SRIM_RS32440	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SRIM_RS32440	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SRIM_RS32445	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SRIM_RS32450	COG0297	glycogen (starch) synthase activity
SRIM_RS32465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SRIM_RS32475	COG2192	nodulation
SRIM_RS32480	COG1088	dTDP-glucose 4,6-dehydratase activity
SRIM_RS32490	COG0859	PFAM glycosyl transferase family 9
SRIM_RS32520	COG2936	dipeptidyl-peptidase activity
SRIM_RS32545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SRIM_RS32550	COG1116	anion transmembrane transporter activity
SRIM_RS32550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SRIM_RS32575	COG0529	Catalyzes the synthesis of activated sulfate
SRIM_RS32580	COG0175	sulfate reduction
SRIM_RS32590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIM_RS32615	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS32665	COG1414	Transcriptional regulator
SRIM_RS32670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SRIM_RS32675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SRIM_RS32680	COG0183	Belongs to the thiolase family
SRIM_RS32685	COG3485	protocatechuate 3,4-dioxygenase
SRIM_RS32690	COG3485	protocatechuate 3,4-dioxygenase
SRIM_RS32695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SRIM_RS32700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIM_RS32735	COG0028	Belongs to the TPP enzyme family
SRIM_RS32770	COG1309	transcriptional regulator
SRIM_RS32785	COG3629	intracellular signal transduction
SRIM_RS32785	COG3903	Transcriptional regulator
SRIM_RS32790	COG1204	response to ionizing radiation
SRIM_RS32820	COG1162	GTPase activity
SRIM_RS32835	COG0028	Belongs to the TPP enzyme family
SRIM_RS32885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SRIM_RS32890	COG2252	PERMEase
SRIM_RS32910	COG1733	regulation of RNA biosynthetic process
SRIM_RS32925	COG1285	pathogenesis
SRIM_RS32930	COG4552	Acetyltransferase involved in intracellular survival and related
SRIM_RS32935	COG0583	DNA-binding transcription factor activity
SRIM_RS32950	COG2197	response regulator
SRIM_RS32955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SRIM_RS32960	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS32990	COG1126	abc transporter atp-binding protein
SRIM_RS33000	COG0753	catalase activity
SRIM_RS33010	COG2084	Dehydrogenase
SRIM_RS33015	COG3622	Belongs to the hyi family
SRIM_RS33035	COG2351	hydroxyisourate hydrolase activity
SRIM_RS33045	COG2233	PERMEase
SRIM_RS33055	COG2233	PERMEase
SRIM_RS33080	COG1288	antiporter activity
SRIM_RS33090	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SRIM_RS33105	COG1414	Transcriptional regulator
SRIM_RS33110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SRIM_RS33115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SRIM_RS33115	COG0237	dephospho-CoA kinase activity
SRIM_RS33160	COG0800	Aldolase
SRIM_RS33175	COG1902	pentaerythritol trinitrate reductase activity
SRIM_RS33180	COG0789	Transcriptional regulator
SRIM_RS33185	COG2188	Transcriptional regulator
SRIM_RS33210	COG1940	carbohydrate kinase activity
SRIM_RS33225	COG0583	DNA-binding transcription factor activity
SRIM_RS33230	COG0251	oxidation-reduction process
SRIM_RS33265	COG2814	Major facilitator Superfamily
SRIM_RS33290	COG3693	PFAM glycoside hydrolase, family 10
SRIM_RS33300	COG0542	response to heat
SRIM_RS33305	COG0583	DNA-binding transcription factor activity
SRIM_RS33310	COG0483	inositol monophosphate 1-phosphatase activity
SRIM_RS33320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIM_RS33350	COG1126	abc transporter atp-binding protein
SRIM_RS33355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRIM_RS33360	COG0765	amino acid transport
SRIM_RS33365	COG0765	amino acid transport
SRIM_RS33375	COG1017	nitric oxide dioxygenase activity
SRIM_RS33375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SRIM_RS33380	COG1959	2 iron, 2 sulfur cluster binding
SRIM_RS33410	COG0405	Gamma-glutamyltransferase
SRIM_RS33430	COG1335	isochorismatase
SRIM_RS33435	COG0477	Major facilitator Superfamily
SRIM_RS33445	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS33460	COG0723	plastoquinol--plastocyanin reductase activity
SRIM_RS33460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIM_RS33475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRIM_RS33480	COG1278	Cold shock
SRIM_RS33485	COG1064	alcohol dehydrogenase
SRIM_RS33505	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SRIM_RS33515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIM_RS33530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SRIM_RS33540	COG0483	inositol monophosphate 1-phosphatase activity
SRIM_RS33550	COG0640	Transcriptional regulator
SRIM_RS33575	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SRIM_RS33590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SRIM_RS33610	COG2304	oxidoreductase activity
SRIM_RS33625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SRIM_RS33630	COG1929	Belongs to the glycerate kinase type-1 family
SRIM_RS33640	COG0688	phosphatidylethanolamine metabolic process
SRIM_RS33645	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS33655	COG2301	Belongs to the HpcH HpaI aldolase family
SRIM_RS33660	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SRIM_RS33660	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SRIM_RS33675	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIM_RS33685	COG0456	acetyltransferase
SRIM_RS33720	COG2207	Transcriptional regulator
SRIM_RS33725	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIM_RS33725	COG2172	sigma factor antagonist activity
SRIM_RS33725	COG2208	phosphoserine phosphatase activity
SRIM_RS33740	COG2362	D-Aminopeptidase
SRIM_RS33745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIM_RS33755	COG1619	proteins homologs of microcin C7 resistance protein MccF
SRIM_RS33770	COG2124	cytochrome p450
SRIM_RS33790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIM_RS33810	COG0010	Belongs to the arginase family
SRIM_RS33840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIM_RS33865	COG2226	methyltransferase
SRIM_RS33870	COG0671	phosphoesterase, PA-phosphatase related
SRIM_RS33875	COG0517	IMP dehydrogenase activity
SRIM_RS33885	COG4948	Mandelate Racemase Muconate Lactonizing
SRIM_RS33895	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS33925	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SRIM_RS33930	COG0583	DNA-binding transcription factor activity
SRIM_RS33945	COG0431	NADPH-dependent FMN reductase
SRIM_RS33955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIM_RS33965	COG0531	amino acid
SRIM_RS33970	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS33975	COG1309	transcriptional regulator
SRIM_RS33980	COG0789	Transcriptional regulator
SRIM_RS34010	COG4941	Belongs to the sigma-70 factor family
SRIM_RS34015	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SRIM_RS34020	COG2154	pterin-4-alpha-carbinolamine dehydratase
SRIM_RS34025	COG1295	ribonuclease BN
SRIM_RS34030	COG1595	DNA-templated transcription, initiation
SRIM_RS34050	COG4106	trans-aconitate 2-methyltransferase activity
SRIM_RS34055	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS34075	COG0656	L-ascorbic acid biosynthetic process
SRIM_RS34095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIM_RS34105	COG0583	DNA-binding transcription factor activity
SRIM_RS34140	COG1063	alcohol dehydrogenase
SRIM_RS34150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SRIM_RS34165	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS34205	COG1605	Chorismate mutase
SRIM_RS34205	COG0287	Prephenate dehydrogenase
SRIM_RS34215	COG2223	nitrite transmembrane transporter activity
SRIM_RS34225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIM_RS34245	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SRIM_RS34260	COG1132	(ABC) transporter
SRIM_RS34280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS34290	COG0475	glutathione-regulated potassium exporter activity
SRIM_RS34300	COG2124	cytochrome p450
SRIM_RS34305	COG2124	cytochrome p450
SRIM_RS34330	COG0287	Prephenate dehydrogenase
SRIM_RS34360	COG3511	phospholipase C
SRIM_RS34370	COG0204	Acyl-transferase
SRIM_RS34405	COG2124	cytochrome p450
SRIM_RS34425	COG1376	ErfK ybiS ycfS ynhG family protein
SRIM_RS34440	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS34445	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS34490	COG0583	DNA-binding transcription factor activity
SRIM_RS34535	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SRIM_RS34545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SRIM_RS34575	COG2205	protein histidine kinase activity
SRIM_RS34580	COG0745	RESPONSE REGULATOR receiver
SRIM_RS34605	COG3226	Transcriptional regulator
SRIM_RS34615	COG0667	Aldo Keto reductase
SRIM_RS34645	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIM_RS34650	COG1846	Transcriptional regulator
SRIM_RS34655	COG1289	transmembrane transporter activity
SRIM_RS34660	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS34665	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS34670	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS34675	COG1309	transcriptional regulator
SRIM_RS34700	COG1024	Enoyl-CoA hydratase
SRIM_RS34700	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIM_RS34705	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS34710	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS34725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SRIM_RS34775	COG1349	DNA-binding transcription factor activity
SRIM_RS34785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SRIM_RS34790	COG2814	Major facilitator Superfamily
SRIM_RS34820	COG1309	transcriptional regulator
SRIM_RS34825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SRIM_RS34830	COG1515	deoxyribonuclease V activity
SRIM_RS34835	COG3268	Saccharopine dehydrogenase
SRIM_RS34840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRIM_RS34855	COG1285	pathogenesis
SRIM_RS34860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIM_RS34865	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS34870	COG0183	Belongs to the thiolase family
SRIM_RS34875	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIM_RS34875	COG1024	Enoyl-CoA hydratase
SRIM_RS34890	COG1113	amino acid transport
SRIM_RS34895	COG0477	Major facilitator Superfamily
SRIM_RS34910	COG2197	response regulator
SRIM_RS34915	COG3568	Endonuclease Exonuclease Phosphatase
SRIM_RS34930	COG2936	dipeptidyl-peptidase activity
SRIM_RS34940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SRIM_RS34965	COG2183	response to ionizing radiation
SRIM_RS34980	COG4977	sequence-specific DNA binding
SRIM_RS35000	COG1024	Enoyl-CoA hydratase
SRIM_RS35010	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SRIM_RS35015	COG1846	Transcriptional regulator
SRIM_RS35035	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SRIM_RS35075	COG1134	teichoic acid transport
SRIM_RS35080	COG1562	ergosterol biosynthetic process
SRIM_RS35090	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SRIM_RS35100	COG1657	PFAM Prenyltransferase squalene oxidase
SRIM_RS35115	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SRIM_RS35120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SRIM_RS35135	COG2365	Tyrosine phosphatase family
SRIM_RS35140	COG2755	lipolytic protein G-D-S-L family
SRIM_RS35195	COG2814	Major facilitator Superfamily
SRIM_RS35205	COG0367	asparagine synthase
SRIM_RS35235	COG2018	Roadblock/LC7 domain
SRIM_RS35255	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS35265	COG0402	S-adenosylhomocysteine deaminase activity
SRIM_RS35270	COG2267	carboxylic ester hydrolase activity
SRIM_RS35275	COG3958	Transketolase
SRIM_RS35280	COG3959	Transketolase, thiamine diphosphate binding domain
SRIM_RS35285	COG0789	Transcriptional regulator
SRIM_RS35315	COG1686	Belongs to the peptidase S11 family
SRIM_RS35345	COG0824	Thioesterase
SRIM_RS35345	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIM_RS35350	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIM_RS35355	COG3246	L-lysine catabolic process to acetate
SRIM_RS35370	COG0174	glutamine synthetase
SRIM_RS35385	COG0583	DNA-binding transcription factor activity
SRIM_RS35395	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SRIM_RS35405	COG1940	carbohydrate kinase activity
SRIM_RS35420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIM_RS35445	COG0789	Transcriptional regulator
SRIM_RS35460	COG4762	Protein conserved in bacteria
SRIM_RS35475	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SRIM_RS35485	COG1024	Enoyl-CoA hydratase
SRIM_RS35490	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS35495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SRIM_RS35525	COG1652	LysM domain
SRIM_RS35545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SRIM_RS35565	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS35570	COG0583	DNA-binding transcription factor activity
SRIM_RS35585	COG1063	alcohol dehydrogenase
SRIM_RS35590	COG0698	ribose 5-phosphate isomerase
SRIM_RS35595	COG0149	triose-phosphate isomerase activity
SRIM_RS35600	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS35630	COG0180	Tryptophanyl-tRNA synthetase
SRIM_RS35635	COG2319	Wd-40 repeat
SRIM_RS35635	COG4249	Peptidase C14 caspase catalytic subunit p20
SRIM_RS35650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIM_RS35670	COG0531	amino acid
SRIM_RS35675	COG3360	Dodecin
SRIM_RS35685	COG1137	ATPase activity
SRIM_RS35775	COG1063	alcohol dehydrogenase
SRIM_RS35780	COG1252	NADH dehydrogenase
SRIM_RS35785	COG3959	Transketolase, thiamine diphosphate binding domain
SRIM_RS35805	COG5479	isomerase activity
SRIM_RS35805	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SRIM_RS35810	COG0823	Involved in the tonB-independent uptake of proteins
SRIM_RS35850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SRIM_RS35855	COG3572	ergothioneine biosynthetic process
SRIM_RS35890	COG2226	methyltransferase
SRIM_RS35895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIM_RS35925	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS35925	COG0604	alcohol dehydrogenase
SRIM_RS35925	COG3321	synthase
SRIM_RS35930	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS35935	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS35970	COG0601	transmembrane transport
SRIM_RS35975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIM_RS36010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIM_RS36020	COG2986	histidine ammonia-lyase
SRIM_RS36025	COG1349	DNA-binding transcription factor activity
SRIM_RS36030	COG2814	Major facilitator Superfamily
SRIM_RS36040	COG1070	Carbohydrate kinase
SRIM_RS36050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SRIM_RS36060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SRIM_RS36060	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SRIM_RS36075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SRIM_RS36080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SRIM_RS36110	COG2267	carboxylic ester hydrolase activity
SRIM_RS36120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIM_RS36120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIM_RS36125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIM_RS36130	COG1846	Transcriptional regulator
SRIM_RS36130	COG1940	carbohydrate kinase activity
SRIM_RS36140	COG1070	Carbohydrate kinase
SRIM_RS36150	COG3458	cephalosporin-C deacetylase activity
SRIM_RS36155	COG1126	abc transporter atp-binding protein
SRIM_RS36160	COG0765	amino acid transport
SRIM_RS36165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRIM_RS36170	COG2040	homocysteine
SRIM_RS36175	COG2353	YceI-like domain
SRIM_RS36200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SRIM_RS36235	COG4122	O-methyltransferase activity
SRIM_RS36255	COG2018	Roadblock/LC7 domain
SRIM_RS36280	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS36285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIM_RS36290	COG0156	8-amino-7-oxononanoate synthase activity
SRIM_RS36300	COG3962	Belongs to the TPP enzyme family
SRIM_RS36305	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS36310	COG1946	Acyl-CoA thioesterase
SRIM_RS36325	COG1132	(ABC) transporter
SRIM_RS36330	COG1132	(ABC) transporter
SRIM_RS36360	COG1132	(ABC) transporter
SRIM_RS36390	COG1556	Lactate utilization protein
SRIM_RS36395	COG1139	Iron-sulfur cluster binding protein
SRIM_RS36400	COG0247	lactate metabolic process
SRIM_RS36405	COG0477	Major facilitator Superfamily
SRIM_RS36435	COG0492	ferredoxin-NADP+ reductase activity
SRIM_RS36450	COG1116	anion transmembrane transporter activity
SRIM_RS36455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SRIM_RS36460	COG0432	Pfam Uncharacterised protein family UPF0047
SRIM_RS36485	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SRIM_RS36485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SRIM_RS36520	COG2175	clavaminate synthase activity
SRIM_RS36535	COG3321	synthase
SRIM_RS36535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS36535	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS36535	COG0300	oxidoreductase activity
SRIM_RS36535	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS36540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS36550	COG1793	dna ligase
SRIM_RS36565	COG1595	DNA-templated transcription, initiation
SRIM_RS36575	COG4257	antibiotic catabolic process
SRIM_RS36580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SRIM_RS36590	COG2391	methyltransferase activity
SRIM_RS36600	COG2706	6-phosphogluconolactonase activity
SRIM_RS36610	COG2971	BadF BadG BcrA BcrD
SRIM_RS36620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SRIM_RS36640	COG1902	pentaerythritol trinitrate reductase activity
SRIM_RS36690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIM_RS36695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SRIM_RS36710	COG3629	intracellular signal transduction
SRIM_RS36715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIM_RS36725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIM_RS36725	COG3320	Male sterility
SRIM_RS36735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SRIM_RS36745	COG2124	cytochrome p450
SRIM_RS36755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SRIM_RS36765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SRIM_RS36770	COG0477	Major facilitator Superfamily
SRIM_RS36780	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SRIM_RS36790	COG0318	PFAM AMP-dependent synthetase and ligase
SRIM_RS36795	COG0517	IMP dehydrogenase activity
SRIM_RS36795	COG0516	GMP reductase activity
SRIM_RS36810	COG0534	Mate efflux family protein
SRIM_RS36830	COG3655	Transcriptional regulator
SRIM_RS36850	COG2814	Major facilitator Superfamily
SRIM_RS36855	COG0640	Transcriptional regulator
SRIM_RS36870	COG0697	spore germination
SRIM_RS36895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SRIM_RS36905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SRIM_RS36920	COG2124	cytochrome p450
SRIM_RS36935	COG0640	Transcriptional regulator
SRIM_RS36945	COG1309	transcriptional regulator
SRIM_RS36960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SRIM_RS36975	COG0604	alcohol dehydrogenase
SRIM_RS36975	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS36975	COG3321	synthase
SRIM_RS36985	COG1116	anion transmembrane transporter activity
SRIM_RS37015	COG4221	oxidoreductase activity
SRIM_RS37065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRIM_RS37070	COG1454	alcohol dehydrogenase
SRIM_RS37105	COG0515	serine threonine protein kinase
SRIM_RS37110	COG1215	transferase activity, transferring glycosyl groups
SRIM_RS37135	COG1585	Membrane protein implicated in regulation of membrane protease activity
SRIM_RS37165	COG2755	lipolytic protein G-D-S-L family
SRIM_RS37190	COG3547	Transposase (IS116 IS110 IS902 family)
SRIM_RS37200	COG3021	interspecies interaction between organisms
SRIM_RS37215	COG2226	methyltransferase
SRIM_RS37235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRIM_RS37345	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SRIM_RS37350	COG1140	nitrate reductase beta subunit
SRIM_RS37385	COG1309	transcriptional regulator
SRIM_RS37575	COG3883	PFAM NLP P60 protein
SRIM_RS37575	COG0791	NLP P60 protein
SRIM_RS37645	COG1181	Belongs to the D-alanine--D-alanine ligase family
SRIM_RS37665	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS37665	COG3321	synthase
SRIM_RS37665	COG0604	alcohol dehydrogenase
SRIM_RS37675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SRIM_RS37715	COG3293	Transposase
SRIM_RS37775	COG1309	transcriptional regulator
SRIM_RS37860	COG0494	nUDIX hydrolase
SRIM_RS37915	COG0739	heme binding
SRIM_RS37940	COG3547	Transposase (IS116 IS110 IS902 family)
SRIM_RS38145	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIM_RS38170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIM_RS38215	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SRIM_RS38215	COG0116	Belongs to the methyltransferase superfamily
SRIM_RS38265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIM_RS38275	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SRIM_RS38280	COG2124	cytochrome p450
SRIM_RS38310	COG2197	response regulator
SRIM_RS38350	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SRIM_RS38355	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS38395	COG0367	asparagine synthase
SRIM_RS38405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIM_RS38425	COG3629	intracellular signal transduction
SRIM_RS38435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SRIM_RS38440	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SRIM_RS38445	COG2080	2 iron, 2 sulfur cluster binding
SRIM_RS38450	COG3800	Transcriptional regulator
SRIM_RS38450	COG1396	sequence-specific DNA binding
SRIM_RS38455	COG2079	MmgE PrpD family protein
SRIM_RS38460	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SRIM_RS38475	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SRIM_RS38500	COG1140	nitrate reductase beta subunit
SRIM_RS38530	COG3387	PFAM Glycoside hydrolase 15-related
SRIM_RS38535	COG0247	lactate metabolic process
SRIM_RS38535	COG0277	FAD linked oxidase domain protein
SRIM_RS38560	COG1595	DNA-templated transcription, initiation
SRIM_RS38610	COG1132	(ABC) transporter
SRIM_RS38620	COG0583	DNA-binding transcription factor activity
SRIM_RS38635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SRIM_RS38640	COG0798	PFAM Bile acid sodium symporter
SRIM_RS38645	COG0640	Transcriptional regulator
SRIM_RS38665	COG0667	Aldo Keto reductase
SRIM_RS38670	COG0604	alcohol dehydrogenase
SRIM_RS38675	COG2207	Transcriptional regulator
SRIM_RS38695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIM_RS38795	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS38805	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SRIM_RS38810	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS38815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS38820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SRIM_RS38825	COG3433	isochorismatase activity
SRIM_RS38825	COG1535	isochorismatase
SRIM_RS38830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIM_RS38845	COG2814	Major facilitator Superfamily
SRIM_RS38850	COG2382	esterase
SRIM_RS38870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SRIM_RS38880	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS38885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIM_RS38915	COG1819	glycosyl
SRIM_RS38920	COG2382	esterase
SRIM_RS38925	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SRIM_RS38930	COG2124	cytochrome p450
SRIM_RS38930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SRIM_RS38955	COG1595	DNA-templated transcription, initiation
SRIM_RS38960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIM_RS38970	COG3979	chitinase
SRIM_RS39020	COG3321	synthase
SRIM_RS39020	COG0604	alcohol dehydrogenase
SRIM_RS39025	COG3321	synthase
SRIM_RS39025	COG0604	alcohol dehydrogenase
SRIM_RS39030	COG3321	synthase
SRIM_RS39030	COG0604	alcohol dehydrogenase
SRIM_RS39035	COG2365	Tyrosine phosphatase family
SRIM_RS39050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SRIM_RS39065	COG0604	alcohol dehydrogenase
SRIM_RS39065	COG3321	synthase
SRIM_RS39075	COG0604	alcohol dehydrogenase
SRIM_RS39125	COG0142	geranyltranstransferase activity
SRIM_RS39155	COG2070	2-Nitropropane dioxygenase
SRIM_RS39160	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS39205	COG2326	polyphosphate kinase activity
SRIM_RS39210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SRIM_RS39215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIM_RS39230	COG0589	response to stress
SRIM_RS39240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SRIM_RS39245	COG0298	carbon dioxide binding
SRIM_RS39250	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SRIM_RS39285	COG0516	GMP reductase activity
SRIM_RS39285	COG0517	IMP dehydrogenase activity
SRIM_RS39315	COG2326	polyphosphate kinase activity
SRIM_RS39320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRIM_RS39325	COG0531	amino acid
SRIM_RS39365	COG3321	synthase
SRIM_RS39365	COG0604	alcohol dehydrogenase
SRIM_RS39430	COG1278	Cold shock
SRIM_RS39440	COG4221	oxidoreductase activity
SRIM_RS39475	COG1012	belongs to the aldehyde dehydrogenase family
SRIM_RS39500	COG1309	transcriptional regulator
SRIM_RS39515	COG0148	phosphopyruvate hydratase activity
SRIM_RS39525	COG1797	cobyrinic acid a,c-diamide synthase activity
SRIM_RS39555	COG1309	transcriptional regulator
SRIM_RS39575	COG1960	acyl-CoA dehydrogenase activity
SRIM_RS39615	COG0463	Glycosyl transferase, family 2
SRIM_RS39620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIM_RS39715	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIM_RS39715	COG2172	sigma factor antagonist activity
SRIM_RS39715	COG2208	phosphoserine phosphatase activity
SRIM_RS39780	COG3012	SEC-C Motif Domain Protein
SRIM_RS39790	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SRIM_RS39815	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SRIM_RS39815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIM_RS39845	COG0142	geranyltranstransferase activity
SRIM_RS39850	COG2197	response regulator
SRIM_RS39870	COG1278	Cold shock
SRIM_RS39885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIM_RS39900	COG1131	(ABC) transporter
SRIM_RS39920	COG0181	hydroxymethylbilane synthase activity
SRIM_RS39940	COG2340	Cysteine-rich secretory protein family
SRIM_RS39950	COG1309	transcriptional regulator
SRIM_RS39970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SRIM_RS39970	COG2755	lipolytic protein G-D-S-L family
SRIM_RS39980	COG0778	Nitroreductase
SRIM_RS40030	COG1309	transcriptional regulator
SRIM_RS40040	COG1396	sequence-specific DNA binding
SRIM_RS40050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRIM_RS40075	COG2910	NAD(P)H-binding
SRIM_RS40110	COG0366	Alpha amylase catalytic
SRIM_RS40115	COG0395	ABC-type sugar transport system, permease component
SRIM_RS40120	COG1175	transmembrane transport
SRIM_RS40150	COG1309	transcriptional regulator
SRIM_RS40160	COG0488	(ABC) transporter
SRIM_RS40165	COG0488	(ABC) transporter
SRIM_RS40200	COG0018	arginyl-trna synthetase
SRIM_RS40225	COG2226	methyltransferase
SRIM_RS40240	COG4999	Histidine kinase
SRIM_RS40240	COG3850	Histidine kinase
SRIM_RS40240	COG3437	response regulator, receiver
SRIM_RS40240	COG2205	protein histidine kinase activity
SRIM_RS40260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SRIM_RS40290	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SRIM_RS40290	COG1672	PFAM Archaeal ATPase
SRIM_RS40305	COG2124	cytochrome p450
SRIM_RS40315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIM_RS40320	COG0367	asparagine synthase
SRIM_RS40325	COG2409	Drug exporters of the RND superfamily
SRIM_RS40415	COG4948	Mandelate Racemase Muconate Lactonizing
SRIM_RS40430	COG1309	transcriptional regulator
SRIM_RS40435	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS40475	COG1051	belongs to the nudix hydrolase family
SRIM_RS40485	COG2814	Major facilitator Superfamily
SRIM_RS40510	COG0583	DNA-binding transcription factor activity
SRIM_RS40520	COG1028	Short-chain dehydrogenase reductase Sdr
SRIM_RS40530	COG0596	Alpha beta hydrolase
SRIM_RS40545	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
SRIM_RS40610	COG2124	cytochrome p450
SRIM_RS40715	COG1309	transcriptional regulator
SRIM_RS40935	COG0431	NADPH-dependent FMN reductase
SRIM_RS40945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIM_RS40955	COG0583	DNA-binding transcription factor activity
SRIM_RS40960	COG2353	YceI-like domain
SRIM_RS41005	COG2234	aminopeptidase activity
SRIM_RS41075	COG4221	oxidoreductase activity
SRIM_RS41195	COG1185	polyribonucleotide nucleotidyltransferase activity
SRIM_RS41405	COG4974	Belongs to the 'phage' integrase family
SRIM_RS41420	COG2801	Transposase and inactivated derivatives
SRIM_RS41420	COG3415	Transposase
SRIM_RS41425	COG1475	DNA binding
SRIM_RS41430	COG1192	Involved in chromosome partitioning
SRIM_RS41545	COG1660	Displays ATPase and GTPase activities
SRIM_RS41670	COG2188	Transcriptional regulator
SRIM_RS41810	COG1309	transcriptional regulator
SRIM_RS41870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SRIM_RS42060	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIM_RS42110	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SRIM_RS42155	COG1074	ATP-dependent DNA helicase activity