locus-tag	class	description
SRIMR7_RS00020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS00075	COG1309	transcriptional regulator
SRIMR7_RS00180	COG2124	cytochrome p450
SRIMR7_RS00235	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
SRIMR7_RS00250	COG0596	Alpha beta hydrolase
SRIMR7_RS00260	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS00270	COG0583	DNA-binding transcription factor activity
SRIMR7_RS00295	COG2814	Major facilitator Superfamily
SRIMR7_RS00305	COG1051	belongs to the nudix hydrolase family
SRIMR7_RS00345	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS00350	COG1309	transcriptional regulator
SRIMR7_RS00365	COG4948	Mandelate Racemase Muconate Lactonizing
SRIMR7_RS00455	COG2409	Drug exporters of the RND superfamily
SRIMR7_RS00460	COG0367	asparagine synthase
SRIMR7_RS00465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIMR7_RS00475	COG2124	cytochrome p450
SRIMR7_RS00490	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SRIMR7_RS00490	COG1672	PFAM Archaeal ATPase
SRIMR7_RS00520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SRIMR7_RS00540	COG4999	Histidine kinase
SRIMR7_RS00540	COG3850	Histidine kinase
SRIMR7_RS00540	COG3437	response regulator, receiver
SRIMR7_RS00540	COG2205	protein histidine kinase activity
SRIMR7_RS00555	COG2226	methyltransferase
SRIMR7_RS00580	COG0018	arginyl-trna synthetase
SRIMR7_RS00615	COG0488	(ABC) transporter
SRIMR7_RS00620	COG0488	(ABC) transporter
SRIMR7_RS00630	COG1309	transcriptional regulator
SRIMR7_RS00660	COG1175	transmembrane transport
SRIMR7_RS00665	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS00670	COG0366	Alpha amylase catalytic
SRIMR7_RS00705	COG2910	NAD(P)H-binding
SRIMR7_RS00730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRIMR7_RS00740	COG1396	sequence-specific DNA binding
SRIMR7_RS00750	COG1309	transcriptional regulator
SRIMR7_RS00770	COG2367	Beta-lactamase
SRIMR7_RS00800	COG0778	Nitroreductase
SRIMR7_RS00810	COG2755	lipolytic protein G-D-S-L family
SRIMR7_RS00810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SRIMR7_RS00830	COG1309	transcriptional regulator
SRIMR7_RS00840	COG2340	Cysteine-rich secretory protein family
SRIMR7_RS00860	COG0181	hydroxymethylbilane synthase activity
SRIMR7_RS00880	COG1131	(ABC) transporter
SRIMR7_RS00895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIMR7_RS00910	COG1278	Cold shock
SRIMR7_RS00930	COG2197	response regulator
SRIMR7_RS00935	COG0142	geranyltranstransferase activity
SRIMR7_RS00965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIMR7_RS00965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SRIMR7_RS00990	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SRIMR7_RS01000	COG3012	SEC-C Motif Domain Protein
SRIMR7_RS01070	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIMR7_RS01070	COG2172	sigma factor antagonist activity
SRIMR7_RS01070	COG2208	phosphoserine phosphatase activity
SRIMR7_RS01170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIMR7_RS01175	COG0463	Glycosyl transferase, family 2
SRIMR7_RS01215	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS01230	COG1309	transcriptional regulator
SRIMR7_RS01260	COG1797	cobyrinic acid a,c-diamide synthase activity
SRIMR7_RS01270	COG0148	phosphopyruvate hydratase activity
SRIMR7_RS01285	COG1309	transcriptional regulator
SRIMR7_RS01310	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS01340	COG4221	oxidoreductase activity
SRIMR7_RS01350	COG1278	Cold shock
SRIMR7_RS01415	COG3321	synthase
SRIMR7_RS01415	COG0604	alcohol dehydrogenase
SRIMR7_RS01455	COG0531	amino acid
SRIMR7_RS01460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRIMR7_RS01465	COG2326	polyphosphate kinase activity
SRIMR7_RS01495	COG0516	GMP reductase activity
SRIMR7_RS01495	COG0517	IMP dehydrogenase activity
SRIMR7_RS01530	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SRIMR7_RS01535	COG0298	carbon dioxide binding
SRIMR7_RS01540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SRIMR7_RS01550	COG0589	response to stress
SRIMR7_RS01565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS01570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SRIMR7_RS01575	COG2326	polyphosphate kinase activity
SRIMR7_RS01620	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS01625	COG2070	2-Nitropropane dioxygenase
SRIMR7_RS01655	COG0142	geranyltranstransferase activity
SRIMR7_RS01710	COG0604	alcohol dehydrogenase
SRIMR7_RS01720	COG0604	alcohol dehydrogenase
SRIMR7_RS01720	COG3321	synthase
SRIMR7_RS01735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SRIMR7_RS01750	COG2365	Tyrosine phosphatase family
SRIMR7_RS01755	COG3321	synthase
SRIMR7_RS01755	COG0604	alcohol dehydrogenase
SRIMR7_RS01760	COG0604	alcohol dehydrogenase
SRIMR7_RS01760	COG3321	synthase
SRIMR7_RS01835	COG3979	chitinase
SRIMR7_RS01845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIMR7_RS01850	COG1595	DNA-templated transcription, initiation
SRIMR7_RS01875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SRIMR7_RS01875	COG2124	cytochrome p450
SRIMR7_RS01880	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SRIMR7_RS01885	COG2382	esterase
SRIMR7_RS01890	COG1819	glycosyl
SRIMR7_RS01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS01925	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS01935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SRIMR7_RS01955	COG2382	esterase
SRIMR7_RS01960	COG2814	Major facilitator Superfamily
SRIMR7_RS01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS01980	COG3433	isochorismatase activity
SRIMR7_RS01980	COG1535	isochorismatase
SRIMR7_RS01985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SRIMR7_RS01990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS01995	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS02000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SRIMR7_RS02010	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS02110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIMR7_RS02130	COG2207	Transcriptional regulator
SRIMR7_RS02135	COG0604	alcohol dehydrogenase
SRIMR7_RS02140	COG0667	Aldo Keto reductase
SRIMR7_RS02160	COG0640	Transcriptional regulator
SRIMR7_RS02165	COG0798	PFAM Bile acid sodium symporter
SRIMR7_RS02170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SRIMR7_RS02185	COG0583	DNA-binding transcription factor activity
SRIMR7_RS02195	COG1132	(ABC) transporter
SRIMR7_RS02245	COG1595	DNA-templated transcription, initiation
SRIMR7_RS02270	COG0247	lactate metabolic process
SRIMR7_RS02270	COG0277	FAD linked oxidase domain protein
SRIMR7_RS02275	COG3387	PFAM Glycoside hydrolase 15-related
SRIMR7_RS02305	COG1140	nitrate reductase beta subunit
SRIMR7_RS02330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SRIMR7_RS02345	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SRIMR7_RS02350	COG2079	MmgE PrpD family protein
SRIMR7_RS02355	COG1396	sequence-specific DNA binding
SRIMR7_RS02355	COG3800	Transcriptional regulator
SRIMR7_RS02360	COG2080	2 iron, 2 sulfur cluster binding
SRIMR7_RS02365	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SRIMR7_RS02370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SRIMR7_RS02380	COG3629	intracellular signal transduction
SRIMR7_RS02400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIMR7_RS02410	COG0367	asparagine synthase
SRIMR7_RS02450	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS02455	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SRIMR7_RS02495	COG2197	response regulator
SRIMR7_RS02525	COG2124	cytochrome p450
SRIMR7_RS02530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SRIMR7_RS02540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIMR7_RS02590	COG0116	Belongs to the methyltransferase superfamily
SRIMR7_RS02590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SRIMR7_RS02630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS02665	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIMR7_RS02780	COG1302	Protein conserved in bacteria
SRIMR7_RS02865	COG3547	Transposase (IS116 IS110 IS902 family)
SRIMR7_RS02890	COG0739	heme binding
SRIMR7_RS02940	COG0494	nUDIX hydrolase
SRIMR7_RS03025	COG1309	transcriptional regulator
SRIMR7_RS03125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SRIMR7_RS03140	COG0604	alcohol dehydrogenase
SRIMR7_RS03140	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS03140	COG3321	synthase
SRIMR7_RS03160	COG1181	Belongs to the D-alanine--D-alanine ligase family
SRIMR7_RS03230	COG3883	PFAM NLP P60 protein
SRIMR7_RS03230	COG0791	NLP P60 protein
SRIMR7_RS03420	COG1309	transcriptional regulator
SRIMR7_RS03455	COG1140	nitrate reductase beta subunit
SRIMR7_RS03460	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SRIMR7_RS03480	COG2197	response regulator
SRIMR7_RS03575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRIMR7_RS03595	COG2226	methyltransferase
SRIMR7_RS03615	COG3021	interspecies interaction between organisms
SRIMR7_RS03625	COG3547	Transposase (IS116 IS110 IS902 family)
SRIMR7_RS03650	COG2755	lipolytic protein G-D-S-L family
SRIMR7_RS03680	COG1585	Membrane protein implicated in regulation of membrane protease activity
SRIMR7_RS03705	COG1215	transferase activity, transferring glycosyl groups
SRIMR7_RS03710	COG0515	serine threonine protein kinase
SRIMR7_RS03745	COG1454	alcohol dehydrogenase
SRIMR7_RS03750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRIMR7_RS03800	COG4221	oxidoreductase activity
SRIMR7_RS03830	COG1116	anion transmembrane transporter activity
SRIMR7_RS03840	COG0604	alcohol dehydrogenase
SRIMR7_RS03840	COG3321	synthase
SRIMR7_RS03840	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS03855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SRIMR7_RS03870	COG1309	transcriptional regulator
SRIMR7_RS03880	COG0640	Transcriptional regulator
SRIMR7_RS03895	COG2124	cytochrome p450
SRIMR7_RS03910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SRIMR7_RS03920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SRIMR7_RS03945	COG0697	spore germination
SRIMR7_RS03960	COG0640	Transcriptional regulator
SRIMR7_RS03965	COG2814	Major facilitator Superfamily
SRIMR7_RS03985	COG3655	Transcriptional regulator
SRIMR7_RS04020	COG0516	GMP reductase activity
SRIMR7_RS04020	COG0517	IMP dehydrogenase activity
SRIMR7_RS04025	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS04035	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SRIMR7_RS04045	COG0477	Major facilitator Superfamily
SRIMR7_RS04050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SRIMR7_RS04060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SRIMR7_RS04070	COG2124	cytochrome p450
SRIMR7_RS04080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SRIMR7_RS04100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIMR7_RS04105	COG3629	intracellular signal transduction
SRIMR7_RS04120	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SRIMR7_RS04125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIMR7_RS04175	COG1902	pentaerythritol trinitrate reductase activity
SRIMR7_RS04195	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SRIMR7_RS04205	COG2971	BadF BadG BcrA BcrD
SRIMR7_RS04215	COG2706	6-phosphogluconolactonase activity
SRIMR7_RS04225	COG2391	methyltransferase activity
SRIMR7_RS04235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SRIMR7_RS04240	COG4257	antibiotic catabolic process
SRIMR7_RS04250	COG1595	DNA-templated transcription, initiation
SRIMR7_RS04265	COG1793	dna ligase
SRIMR7_RS04275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS04280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS04280	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS04280	COG0300	oxidoreductase activity
SRIMR7_RS04280	COG3321	synthase
SRIMR7_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS04295	COG2175	clavaminate synthase activity
SRIMR7_RS04330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SRIMR7_RS04330	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SRIMR7_RS04355	COG0432	Pfam Uncharacterised protein family UPF0047
SRIMR7_RS04360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SRIMR7_RS04365	COG1116	anion transmembrane transporter activity
SRIMR7_RS04380	COG0492	ferredoxin-NADP+ reductase activity
SRIMR7_RS04410	COG0477	Major facilitator Superfamily
SRIMR7_RS04415	COG0247	lactate metabolic process
SRIMR7_RS04420	COG1139	Iron-sulfur cluster binding protein
SRIMR7_RS04425	COG1556	Lactate utilization protein
SRIMR7_RS04455	COG1132	(ABC) transporter
SRIMR7_RS04485	COG1132	(ABC) transporter
SRIMR7_RS04490	COG1132	(ABC) transporter
SRIMR7_RS04505	COG1946	Acyl-CoA thioesterase
SRIMR7_RS04510	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS04515	COG3962	Belongs to the TPP enzyme family
SRIMR7_RS04525	COG0156	8-amino-7-oxononanoate synthase activity
SRIMR7_RS04530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIMR7_RS04535	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS04560	COG2018	Roadblock/LC7 domain
SRIMR7_RS04580	COG4122	O-methyltransferase activity
SRIMR7_RS04615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SRIMR7_RS04640	COG2353	YceI-like domain
SRIMR7_RS04645	COG2040	homocysteine
SRIMR7_RS04650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRIMR7_RS04655	COG0765	amino acid transport
SRIMR7_RS04660	COG1126	abc transporter atp-binding protein
SRIMR7_RS04665	COG3458	cephalosporin-C deacetylase activity
SRIMR7_RS04675	COG1070	Carbohydrate kinase
SRIMR7_RS04685	COG1940	carbohydrate kinase activity
SRIMR7_RS04685	COG1846	Transcriptional regulator
SRIMR7_RS04690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIMR7_RS04695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIMR7_RS04695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIMR7_RS04705	COG2267	carboxylic ester hydrolase activity
SRIMR7_RS04735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SRIMR7_RS04740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SRIMR7_RS04755	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SRIMR7_RS04755	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SRIMR7_RS04765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SRIMR7_RS04775	COG1070	Carbohydrate kinase
SRIMR7_RS04785	COG2814	Major facilitator Superfamily
SRIMR7_RS04790	COG1349	DNA-binding transcription factor activity
SRIMR7_RS04795	COG2986	histidine ammonia-lyase
SRIMR7_RS04805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIMR7_RS04840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIMR7_RS04845	COG0601	transmembrane transport
SRIMR7_RS04880	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS04885	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS04890	COG0604	alcohol dehydrogenase
SRIMR7_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS04890	COG3321	synthase
SRIMR7_RS04920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIMR7_RS04925	COG2226	methyltransferase
SRIMR7_RS04960	COG3572	ergothioneine biosynthetic process
SRIMR7_RS04965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SRIMR7_RS05005	COG0823	Involved in the tonB-independent uptake of proteins
SRIMR7_RS05010	COG5479	isomerase activity
SRIMR7_RS05010	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SRIMR7_RS05030	COG3959	Transketolase, thiamine diphosphate binding domain
SRIMR7_RS05035	COG1252	NADH dehydrogenase
SRIMR7_RS05040	COG1063	alcohol dehydrogenase
SRIMR7_RS05130	COG1137	ATPase activity
SRIMR7_RS05140	COG3360	Dodecin
SRIMR7_RS05145	COG0531	amino acid
SRIMR7_RS05165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIMR7_RS05180	COG2319	Wd-40 repeat
SRIMR7_RS05180	COG4249	Peptidase C14 caspase catalytic subunit p20
SRIMR7_RS05185	COG0180	Tryptophanyl-tRNA synthetase
SRIMR7_RS05215	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS05220	COG0149	triose-phosphate isomerase activity
SRIMR7_RS05225	COG0698	ribose 5-phosphate isomerase
SRIMR7_RS05230	COG1063	alcohol dehydrogenase
SRIMR7_RS05245	COG0583	DNA-binding transcription factor activity
SRIMR7_RS05250	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS05270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SRIMR7_RS05290	COG1652	LysM domain
SRIMR7_RS05320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SRIMR7_RS05325	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS05330	COG1024	Enoyl-CoA hydratase
SRIMR7_RS05340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SRIMR7_RS05355	COG4762	Protein conserved in bacteria
SRIMR7_RS05370	COG0789	Transcriptional regulator
SRIMR7_RS05395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIMR7_RS05410	COG1940	carbohydrate kinase activity
SRIMR7_RS05420	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SRIMR7_RS05430	COG0583	DNA-binding transcription factor activity
SRIMR7_RS05445	COG0174	glutamine synthetase
SRIMR7_RS05460	COG3246	L-lysine catabolic process to acetate
SRIMR7_RS05465	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIMR7_RS05470	COG0824	Thioesterase
SRIMR7_RS05470	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIMR7_RS05500	COG1686	Belongs to the peptidase S11 family
SRIMR7_RS05530	COG0789	Transcriptional regulator
SRIMR7_RS05535	COG3959	Transketolase, thiamine diphosphate binding domain
SRIMR7_RS05540	COG3958	Transketolase
SRIMR7_RS05545	COG2267	carboxylic ester hydrolase activity
SRIMR7_RS05550	COG0402	S-adenosylhomocysteine deaminase activity
SRIMR7_RS05560	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS05580	COG2018	Roadblock/LC7 domain
SRIMR7_RS05610	COG0367	asparagine synthase
SRIMR7_RS05620	COG2814	Major facilitator Superfamily
SRIMR7_RS05675	COG2755	lipolytic protein G-D-S-L family
SRIMR7_RS05680	COG2365	Tyrosine phosphatase family
SRIMR7_RS05695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SRIMR7_RS05700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SRIMR7_RS05715	COG1657	PFAM Prenyltransferase squalene oxidase
SRIMR7_RS05725	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SRIMR7_RS05735	COG1562	ergosterol biosynthetic process
SRIMR7_RS05740	COG1134	teichoic acid transport
SRIMR7_RS05780	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SRIMR7_RS05800	COG1846	Transcriptional regulator
SRIMR7_RS05805	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SRIMR7_RS05815	COG1024	Enoyl-CoA hydratase
SRIMR7_RS05835	COG4977	sequence-specific DNA binding
SRIMR7_RS05850	COG2183	response to ionizing radiation
SRIMR7_RS05875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SRIMR7_RS05885	COG2936	dipeptidyl-peptidase activity
SRIMR7_RS05900	COG3568	Endonuclease Exonuclease Phosphatase
SRIMR7_RS05905	COG2197	response regulator
SRIMR7_RS05920	COG0477	Major facilitator Superfamily
SRIMR7_RS05925	COG1113	amino acid transport
SRIMR7_RS05940	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIMR7_RS05940	COG1024	Enoyl-CoA hydratase
SRIMR7_RS05945	COG0183	Belongs to the thiolase family
SRIMR7_RS05950	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS05955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIMR7_RS05960	COG1285	pathogenesis
SRIMR7_RS05975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRIMR7_RS05980	COG3268	Saccharopine dehydrogenase
SRIMR7_RS05985	COG1515	deoxyribonuclease V activity
SRIMR7_RS05990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SRIMR7_RS05995	COG1309	transcriptional regulator
SRIMR7_RS06025	COG2814	Major facilitator Superfamily
SRIMR7_RS06030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SRIMR7_RS06040	COG1349	DNA-binding transcription factor activity
SRIMR7_RS06090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SRIMR7_RS06105	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS06110	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS06115	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIMR7_RS06115	COG1024	Enoyl-CoA hydratase
SRIMR7_RS06140	COG1309	transcriptional regulator
SRIMR7_RS06145	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS06150	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS06155	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS06160	COG1289	transmembrane transporter activity
SRIMR7_RS06165	COG1846	Transcriptional regulator
SRIMR7_RS06170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIMR7_RS06200	COG0667	Aldo Keto reductase
SRIMR7_RS06210	COG3226	Transcriptional regulator
SRIMR7_RS06235	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS06240	COG2205	protein histidine kinase activity
SRIMR7_RS06270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SRIMR7_RS06280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SRIMR7_RS06325	COG0583	DNA-binding transcription factor activity
SRIMR7_RS06375	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS06380	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS06395	COG1376	ErfK ybiS ycfS ynhG family protein
SRIMR7_RS06415	COG2124	cytochrome p450
SRIMR7_RS06450	COG0204	Acyl-transferase
SRIMR7_RS06460	COG3511	phospholipase C
SRIMR7_RS06490	COG0287	Prephenate dehydrogenase
SRIMR7_RS06515	COG2124	cytochrome p450
SRIMR7_RS06520	COG2124	cytochrome p450
SRIMR7_RS06530	COG0475	glutathione-regulated potassium exporter activity
SRIMR7_RS06540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS06560	COG1132	(ABC) transporter
SRIMR7_RS06575	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SRIMR7_RS06605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIMR7_RS06615	COG2223	nitrite transmembrane transporter activity
SRIMR7_RS06625	COG0287	Prephenate dehydrogenase
SRIMR7_RS06625	COG1605	Chorismate mutase
SRIMR7_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS06680	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SRIMR7_RS06690	COG1063	alcohol dehydrogenase
SRIMR7_RS06725	COG0583	DNA-binding transcription factor activity
SRIMR7_RS06735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIMR7_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS06780	COG4106	trans-aconitate 2-methyltransferase activity
SRIMR7_RS06800	COG1595	DNA-templated transcription, initiation
SRIMR7_RS06805	COG1295	ribonuclease BN
SRIMR7_RS06810	COG2154	pterin-4-alpha-carbinolamine dehydratase
SRIMR7_RS06815	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SRIMR7_RS06820	COG4941	Belongs to the sigma-70 factor family
SRIMR7_RS06850	COG0789	Transcriptional regulator
SRIMR7_RS06855	COG1309	transcriptional regulator
SRIMR7_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS06865	COG0531	amino acid
SRIMR7_RS06875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIMR7_RS06885	COG0431	NADPH-dependent FMN reductase
SRIMR7_RS06900	COG0583	DNA-binding transcription factor activity
SRIMR7_RS06905	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SRIMR7_RS06935	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS06945	COG4948	Mandelate Racemase Muconate Lactonizing
SRIMR7_RS06955	COG0517	IMP dehydrogenase activity
SRIMR7_RS06960	COG0671	phosphoesterase, PA-phosphatase related
SRIMR7_RS06965	COG2226	methyltransferase
SRIMR7_RS06990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIMR7_RS07020	COG0010	Belongs to the arginase family
SRIMR7_RS07040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIMR7_RS07060	COG2124	cytochrome p450
SRIMR7_RS07075	COG1619	proteins homologs of microcin C7 resistance protein MccF
SRIMR7_RS07085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIMR7_RS07090	COG2362	D-Aminopeptidase
SRIMR7_RS07105	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIMR7_RS07105	COG2208	phosphoserine phosphatase activity
SRIMR7_RS07105	COG2172	sigma factor antagonist activity
SRIMR7_RS07110	COG2207	Transcriptional regulator
SRIMR7_RS07145	COG0456	acetyltransferase
SRIMR7_RS07155	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIMR7_RS07170	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SRIMR7_RS07170	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SRIMR7_RS07175	COG2301	Belongs to the HpcH HpaI aldolase family
SRIMR7_RS07185	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS07190	COG0688	phosphatidylethanolamine metabolic process
SRIMR7_RS07200	COG1929	Belongs to the glycerate kinase type-1 family
SRIMR7_RS07205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SRIMR7_RS07225	COG2304	oxidoreductase activity
SRIMR7_RS07245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SRIMR7_RS07260	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SRIMR7_RS07285	COG0640	Transcriptional regulator
SRIMR7_RS07295	COG0483	inositol monophosphate 1-phosphatase activity
SRIMR7_RS07305	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SRIMR7_RS07320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIMR7_RS07330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SRIMR7_RS07350	COG1064	alcohol dehydrogenase
SRIMR7_RS07355	COG1278	Cold shock
SRIMR7_RS07360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRIMR7_RS07375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIMR7_RS07375	COG0723	plastoquinol--plastocyanin reductase activity
SRIMR7_RS07390	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS07400	COG0477	Major facilitator Superfamily
SRIMR7_RS07405	COG1335	isochorismatase
SRIMR7_RS07425	COG0405	Gamma-glutamyltransferase
SRIMR7_RS07455	COG1959	2 iron, 2 sulfur cluster binding
SRIMR7_RS07460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SRIMR7_RS07460	COG1017	nitric oxide dioxygenase activity
SRIMR7_RS07470	COG0765	amino acid transport
SRIMR7_RS07475	COG0765	amino acid transport
SRIMR7_RS07480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRIMR7_RS07485	COG1126	abc transporter atp-binding protein
SRIMR7_RS07515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIMR7_RS07525	COG0483	inositol monophosphate 1-phosphatase activity
SRIMR7_RS07530	COG0583	DNA-binding transcription factor activity
SRIMR7_RS07535	COG0542	response to heat
SRIMR7_RS07545	COG3693	PFAM glycoside hydrolase, family 10
SRIMR7_RS07570	COG2814	Major facilitator Superfamily
SRIMR7_RS07605	COG0251	oxidation-reduction process
SRIMR7_RS07610	COG0583	DNA-binding transcription factor activity
SRIMR7_RS07625	COG1940	carbohydrate kinase activity
SRIMR7_RS07650	COG2188	Transcriptional regulator
SRIMR7_RS07655	COG0789	Transcriptional regulator
SRIMR7_RS07660	COG1902	pentaerythritol trinitrate reductase activity
SRIMR7_RS07675	COG0800	Aldolase
SRIMR7_RS07715	COG0237	dephospho-CoA kinase activity
SRIMR7_RS07715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SRIMR7_RS07720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SRIMR7_RS07725	COG1414	Transcriptional regulator
SRIMR7_RS07740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SRIMR7_RS07750	COG1288	antiporter activity
SRIMR7_RS07775	COG2233	PERMEase
SRIMR7_RS07785	COG2233	PERMEase
SRIMR7_RS07795	COG2351	hydroxyisourate hydrolase activity
SRIMR7_RS07815	COG3622	Belongs to the hyi family
SRIMR7_RS07820	COG2084	Dehydrogenase
SRIMR7_RS07830	COG0753	catalase activity
SRIMR7_RS07840	COG1126	abc transporter atp-binding protein
SRIMR7_RS07870	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS07875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SRIMR7_RS07880	COG2197	response regulator
SRIMR7_RS07895	COG0583	DNA-binding transcription factor activity
SRIMR7_RS07900	COG4552	Acetyltransferase involved in intracellular survival and related
SRIMR7_RS07905	COG1285	pathogenesis
SRIMR7_RS07920	COG1733	regulation of RNA biosynthetic process
SRIMR7_RS07940	COG2252	PERMEase
SRIMR7_RS07945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SRIMR7_RS07995	COG0028	Belongs to the TPP enzyme family
SRIMR7_RS08015	COG1162	GTPase activity
SRIMR7_RS08045	COG1204	response to ionizing radiation
SRIMR7_RS08050	COG3903	Transcriptional regulator
SRIMR7_RS08050	COG3629	intracellular signal transduction
SRIMR7_RS08065	COG1309	transcriptional regulator
SRIMR7_RS08100	COG0028	Belongs to the TPP enzyme family
SRIMR7_RS08135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIMR7_RS08140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SRIMR7_RS08145	COG3485	protocatechuate 3,4-dioxygenase
SRIMR7_RS08150	COG3485	protocatechuate 3,4-dioxygenase
SRIMR7_RS08155	COG0183	Belongs to the thiolase family
SRIMR7_RS08160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SRIMR7_RS08165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SRIMR7_RS08170	COG1414	Transcriptional regulator
SRIMR7_RS08220	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS08245	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIMR7_RS08255	COG0175	sulfate reduction
SRIMR7_RS08260	COG0529	Catalyzes the synthesis of activated sulfate
SRIMR7_RS08285	COG1116	anion transmembrane transporter activity
SRIMR7_RS08285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SRIMR7_RS08290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SRIMR7_RS08315	COG2936	dipeptidyl-peptidase activity
SRIMR7_RS08345	COG0859	PFAM glycosyl transferase family 9
SRIMR7_RS08355	COG1088	dTDP-glucose 4,6-dehydratase activity
SRIMR7_RS08360	COG2192	nodulation
SRIMR7_RS08370	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SRIMR7_RS08385	COG0297	glycogen (starch) synthase activity
SRIMR7_RS08390	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SRIMR7_RS08395	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SRIMR7_RS08395	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SRIMR7_RS08405	COG1215	transferase activity, transferring glycosyl groups
SRIMR7_RS08480	COG2362	D-Aminopeptidase
SRIMR7_RS08485	COG0583	DNA-binding transcription factor activity
SRIMR7_RS08490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SRIMR7_RS08520	COG0693	protein deglycase activity
SRIMR7_RS08530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SRIMR7_RS08535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SRIMR7_RS08540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SRIMR7_RS08545	COG2197	response regulator
SRIMR7_RS08550	COG4585	Histidine kinase
SRIMR7_RS08560	COG1136	(ABC) transporter
SRIMR7_RS08590	COG4152	abc transporter atp-binding protein
SRIMR7_RS08620	COG1280	lysine exporter protein (LysE YggA)
SRIMR7_RS08625	COG3220	belongs to the UPF0276 family
SRIMR7_RS08650	COG3253	May function as heme-dependent peroxidase
SRIMR7_RS08655	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SRIMR7_RS08665	COG0183	Belongs to the thiolase family
SRIMR7_RS08680	COG0446	pyridine nucleotide-disulphide oxidoreductase
SRIMR7_RS08685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SRIMR7_RS08700	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SRIMR7_RS08710	COG0183	Belongs to the thiolase family
SRIMR7_RS08715	COG1024	Enoyl-CoA hydratase
SRIMR7_RS08715	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIMR7_RS08730	COG0531	amino acid
SRIMR7_RS08735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SRIMR7_RS08740	COG4214	carbohydrate transport
SRIMR7_RS08750	COG4213	ABC transporter substrate-binding protein
SRIMR7_RS08755	COG1940	carbohydrate kinase activity
SRIMR7_RS08760	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS08765	COG1175	transmembrane transport
SRIMR7_RS08770	COG1653	transport
SRIMR7_RS08785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SRIMR7_RS08790	COG4106	trans-aconitate 2-methyltransferase activity
SRIMR7_RS08800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SRIMR7_RS08815	COG0596	Alpha beta hydrolase
SRIMR7_RS08830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SRIMR7_RS08835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SRIMR7_RS08850	COG2223	nitrite transmembrane transporter activity
SRIMR7_RS08865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SRIMR7_RS08875	COG1063	alcohol dehydrogenase
SRIMR7_RS08900	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS08905	COG1024	Enoyl-CoA hydratase
SRIMR7_RS08925	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS08940	COG0546	phosphoglycolate phosphatase activity
SRIMR7_RS08965	COG1024	Enoyl-CoA hydratase
SRIMR7_RS08970	COG0531	amino acid
SRIMR7_RS08975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SRIMR7_RS08980	COG2235	arginine
SRIMR7_RS09050	COG2197	response regulator
SRIMR7_RS09090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SRIMR7_RS09105	COG2770	Histidine kinase
SRIMR7_RS09105	COG2208	phosphoserine phosphatase activity
SRIMR7_RS09145	COG1799	cell septum assembly
SRIMR7_RS09150	COG0598	Magnesium transport protein CorA
SRIMR7_RS09160	COG0302	gtp cyclohydrolase
SRIMR7_RS09175	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SRIMR7_RS09195	COG4638	Rieske (2fe-2S)
SRIMR7_RS09200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SRIMR7_RS09215	COG2986	histidine ammonia-lyase
SRIMR7_RS09220	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS09225	COG0156	8-amino-7-oxononanoate synthase activity
SRIMR7_RS09240	COG2814	Major facilitator Superfamily
SRIMR7_RS09245	COG0583	DNA-binding transcription factor activity
SRIMR7_RS09265	COG2201	protein-glutamate methylesterase activity
SRIMR7_RS09290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIMR7_RS09295	COG0601	transmembrane transport
SRIMR7_RS09300	COG0747	negative chemotaxis
SRIMR7_RS09315	COG4948	Mandelate Racemase Muconate Lactonizing
SRIMR7_RS09320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIMR7_RS09330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SRIMR7_RS09355	COG0583	DNA-binding transcription factor activity
SRIMR7_RS09365	COG0702	epimerase
SRIMR7_RS09385	COG1535	isochorismatase
SRIMR7_RS09385	COG3433	isochorismatase activity
SRIMR7_RS09390	COG1535	isochorismatase
SRIMR7_RS09390	COG3433	isochorismatase activity
SRIMR7_RS09395	COG1021	2,3-dihydroxybenzoate-AMP ligase
SRIMR7_RS09400	COG1169	isochorismate synthase
SRIMR7_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS09410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS09415	COG2382	esterase
SRIMR7_RS09420	COG2814	Major facilitator Superfamily
SRIMR7_RS09425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS09435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SRIMR7_RS09440	COG1120	ATPase activity
SRIMR7_RS09455	COG2264	protein methyltransferase activity
SRIMR7_RS09485	COG2124	cytochrome p450
SRIMR7_RS09490	COG0477	Major facilitator Superfamily
SRIMR7_RS09550	COG3842	ATPase activity
SRIMR7_RS09565	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SRIMR7_RS09570	COG0066	3-isopropylmalate dehydratase activity
SRIMR7_RS09590	COG2197	response regulator
SRIMR7_RS09615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS09650	COG1834	amidinotransferase
SRIMR7_RS09655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SRIMR7_RS09660	COG0134	indole-3-glycerol-phosphate synthase activity
SRIMR7_RS09665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SRIMR7_RS09675	COG0512	Glutamine amidotransferase of anthranilate synthase
SRIMR7_RS09675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SRIMR7_RS09685	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SRIMR7_RS09710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS09715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS09730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SRIMR7_RS09735	COG0531	amino acid
SRIMR7_RS09765	COG0569	domain protein
SRIMR7_RS09800	COG0577	efflux transmembrane transporter activity
SRIMR7_RS09800	COG1136	(ABC) transporter
SRIMR7_RS09810	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SRIMR7_RS09815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SRIMR7_RS09820	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SRIMR7_RS09835	COG0756	dUTP diphosphatase activity
SRIMR7_RS09860	COG2205	protein histidine kinase activity
SRIMR7_RS09865	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS09875	COG0483	inositol monophosphate 1-phosphatase activity
SRIMR7_RS09880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SRIMR7_RS09915	COG1435	thymidine kinase activity
SRIMR7_RS09935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SRIMR7_RS09940	COG1802	Transcriptional regulator
SRIMR7_RS09955	COG0612	Peptidase, M16
SRIMR7_RS09960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SRIMR7_RS09970	COG0372	Belongs to the citrate synthase family
SRIMR7_RS09975	COG0372	Belongs to the citrate synthase family
SRIMR7_RS09995	COG3290	protein histidine kinase activity
SRIMR7_RS10000	COG4565	transcriptional regulatory protein
SRIMR7_RS10005	COG2197	response regulator
SRIMR7_RS10010	COG4585	Histidine kinase
SRIMR7_RS10020	COG0187	DNA topoisomerase II activity
SRIMR7_RS10035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SRIMR7_RS10040	COG2186	Transcriptional regulator
SRIMR7_RS10065	COG0514	ATP-dependent DNA helicase (RecQ)
SRIMR7_RS10080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SRIMR7_RS10095	COG0488	(ABC) transporter
SRIMR7_RS10110	COG0154	amidase activity
SRIMR7_RS10115	COG3226	Transcriptional regulator
SRIMR7_RS10130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SRIMR7_RS10135	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SRIMR7_RS10140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SRIMR7_RS10175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SRIMR7_RS10185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SRIMR7_RS10190	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SRIMR7_RS10200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SRIMR7_RS10220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SRIMR7_RS10235	COG1278	Cold shock
SRIMR7_RS10240	COG2205	protein histidine kinase activity
SRIMR7_RS10250	COG1126	abc transporter atp-binding protein
SRIMR7_RS10260	COG0765	amino acid transport
SRIMR7_RS10265	COG0765	amino acid transport
SRIMR7_RS10305	COG0628	permease
SRIMR7_RS10330	COG2207	Transcriptional regulator
SRIMR7_RS10330	COG1917	Cupin 2, conserved barrel domain protein
SRIMR7_RS10335	COG1201	RNA secondary structure unwinding
SRIMR7_RS10340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SRIMR7_RS10350	COG0181	hydroxymethylbilane synthase activity
SRIMR7_RS10365	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS10370	COG0783	Belongs to the Dps family
SRIMR7_RS10375	COG1396	sequence-specific DNA binding
SRIMR7_RS10380	COG1546	Belongs to the CinA family
SRIMR7_RS10380	COG1058	Belongs to the CinA family
SRIMR7_RS10390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SRIMR7_RS10400	COG1674	ftsk spoiiie
SRIMR7_RS10410	COG4999	Histidine kinase
SRIMR7_RS10410	COG3850	Histidine kinase
SRIMR7_RS10410	COG3437	response regulator, receiver
SRIMR7_RS10410	COG2205	protein histidine kinase activity
SRIMR7_RS10415	COG2770	Histidine kinase
SRIMR7_RS10415	COG2208	phosphoserine phosphatase activity
SRIMR7_RS10445	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SRIMR7_RS10450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRIMR7_RS10455	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SRIMR7_RS10475	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SRIMR7_RS10480	COG0612	Peptidase, M16
SRIMR7_RS10485	COG1185	polyribonucleotide nucleotidyltransferase activity
SRIMR7_RS10490	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SRIMR7_RS10500	COG1674	ftsk spoiiie
SRIMR7_RS10620	COG0455	bacterial-type flagellum organization
SRIMR7_RS10630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SRIMR7_RS10635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SRIMR7_RS10645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SRIMR7_RS10660	COG0779	Required for maturation of 30S ribosomal subunits
SRIMR7_RS10675	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SRIMR7_RS10680	COG0442	prolyl-tRNA aminoacylation
SRIMR7_RS10695	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SRIMR7_RS10700	COG0750	zinc metalloprotease
SRIMR7_RS10705	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SRIMR7_RS10720	COG2197	response regulator
SRIMR7_RS10725	COG4585	Histidine kinase
SRIMR7_RS10730	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS10815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIMR7_RS10820	COG1177	transmembrane transport
SRIMR7_RS10825	COG1176	ABC-type spermidine putrescine transport system, permease component I
SRIMR7_RS10830	COG3842	ATPase activity
SRIMR7_RS10840	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS10855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SRIMR7_RS10880	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS10890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SRIMR7_RS10915	COG3842	ATPase activity
SRIMR7_RS10920	COG4208	sulfate ABC transporter
SRIMR7_RS10930	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SRIMR7_RS10940	COG0233	cytoplasmic translational termination
SRIMR7_RS10945	COG0528	UMP kinase activity
SRIMR7_RS10950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SRIMR7_RS10955	COG0052	Belongs to the universal ribosomal protein uS2 family
SRIMR7_RS10985	COG0792	nuclease activity
SRIMR7_RS11005	COG0681	Belongs to the peptidase S26 family
SRIMR7_RS11015	COG0681	Belongs to the peptidase S26 family
SRIMR7_RS11020	COG0335	large ribosomal subunit rRNA binding
SRIMR7_RS11025	COG0336	Belongs to the RNA methyltransferase TrmD family
SRIMR7_RS11030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SRIMR7_RS11035	COG1837	Belongs to the UPF0109 family
SRIMR7_RS11040	COG0228	four-way junction DNA binding
SRIMR7_RS11075	COG1735	metal-dependent hydrolase with the TIM-barrel fold
SRIMR7_RS11080	COG0626	cystathionine gamma-synthase activity
SRIMR7_RS11090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SRIMR7_RS11105	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SRIMR7_RS11140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SRIMR7_RS11150	COG0477	Major facilitator Superfamily
SRIMR7_RS11155	COG1196	nuclear chromosome segregation
SRIMR7_RS11165	COG1254	Belongs to the acylphosphatase family
SRIMR7_RS11185	COG1733	regulation of RNA biosynthetic process
SRIMR7_RS11190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SRIMR7_RS11195	COG0571	ribonuclease III activity
SRIMR7_RS11200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SRIMR7_RS11215	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SRIMR7_RS11220	COG0742	ribosomal rna small subunit methyltransferase
SRIMR7_RS11230	COG1461	Dihydroxyacetone kinase
SRIMR7_RS11235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SRIMR7_RS11240	COG0351	phosphomethylpyrimidine kinase
SRIMR7_RS11260	COG1181	Belongs to the D-alanine--D-alanine ligase family
SRIMR7_RS11265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SRIMR7_RS11275	COG1920	GTP binding
SRIMR7_RS11285	COG0776	regulation of translation
SRIMR7_RS11295	COG0066	3-isopropylmalate dehydratase activity
SRIMR7_RS11300	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SRIMR7_RS11305	COG1414	Transcriptional regulator
SRIMR7_RS11395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SRIMR7_RS11400	COG0179	Fumarylacetoacetate (FAA) hydrolase
SRIMR7_RS11415	COG2018	Roadblock/LC7 domain
SRIMR7_RS11435	COG2018	Roadblock/LC7 domain
SRIMR7_RS11450	COG2376	Dihydroxyacetone kinase
SRIMR7_RS11455	COG2814	Major facilitator Superfamily
SRIMR7_RS11470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SRIMR7_RS11475	COG5492	domain, Protein
SRIMR7_RS11480	COG2353	YceI-like domain
SRIMR7_RS11485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SRIMR7_RS11490	COG0477	Major facilitator Superfamily
SRIMR7_RS11500	COG1309	transcriptional regulator
SRIMR7_RS11505	COG2957	Belongs to the agmatine deiminase family
SRIMR7_RS11510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SRIMR7_RS11515	COG0473	3-isopropylmalate dehydrogenase activity
SRIMR7_RS11530	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS11535	COG0506	proline dehydrogenase activity
SRIMR7_RS11540	COG3835	regulator
SRIMR7_RS11560	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SRIMR7_RS11565	COG0440	acetolactate synthase activity
SRIMR7_RS11585	COG0667	Aldo Keto reductase
SRIMR7_RS11590	COG2133	pyrroloquinoline quinone binding
SRIMR7_RS11600	COG2197	response regulator
SRIMR7_RS11615	COG2409	Drug exporters of the RND superfamily
SRIMR7_RS11620	COG3511	phospholipase C
SRIMR7_RS11665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SRIMR7_RS11675	COG0154	amidase activity
SRIMR7_RS11680	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SRIMR7_RS11690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SRIMR7_RS11700	COG4221	oxidoreductase activity
SRIMR7_RS11710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SRIMR7_RS11725	COG0667	Aldo Keto reductase
SRIMR7_RS11730	COG0482	sulfurtransferase activity
SRIMR7_RS11755	COG3903	Transcriptional regulator
SRIMR7_RS11755	COG3629	intracellular signal transduction
SRIMR7_RS11780	COG2860	membrane
SRIMR7_RS11800	COG4608	Belongs to the ABC transporter superfamily
SRIMR7_RS11805	COG0444	Belongs to the ABC transporter superfamily
SRIMR7_RS11810	COG0601	transmembrane transport
SRIMR7_RS11815	COG0747	negative chemotaxis
SRIMR7_RS11820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIMR7_RS11845	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SRIMR7_RS11850	COG0509	glycine decarboxylation via glycine cleavage system
SRIMR7_RS11855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SRIMR7_RS11860	COG0531	amino acid
SRIMR7_RS11865	COG1760	l-serine dehydratase
SRIMR7_RS11905	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SRIMR7_RS11925	COG0785	Cytochrome C biogenesis protein
SRIMR7_RS11930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SRIMR7_RS11930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SRIMR7_RS11955	COG1376	ErfK ybiS ycfS ynhG family protein
SRIMR7_RS11965	COG1132	(ABC) transporter
SRIMR7_RS11970	COG1132	(ABC) transporter
SRIMR7_RS11975	COG0477	Major facilitator Superfamily
SRIMR7_RS11980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SRIMR7_RS11985	COG2272	Belongs to the type-B carboxylesterase lipase family
SRIMR7_RS11990	COG1252	NADH dehydrogenase
SRIMR7_RS11995	COG1595	DNA-templated transcription, initiation
SRIMR7_RS12000	COG2318	DinB family
SRIMR7_RS12015	COG2197	response regulator
SRIMR7_RS12040	COG0058	SHG alpha-glucan phosphorylase activity
SRIMR7_RS12050	COG0366	Alpha amylase catalytic
SRIMR7_RS12055	COG0366	Alpha amylase catalytic
SRIMR7_RS12065	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SRIMR7_RS12070	COG0667	Aldo Keto reductase
SRIMR7_RS12085	COG0477	Major facilitator Superfamily
SRIMR7_RS12095	COG1301	dicarboxylic acid transport
SRIMR7_RS12100	COG3290	protein histidine kinase activity
SRIMR7_RS12105	COG4565	transcriptional regulatory protein
SRIMR7_RS12115	COG1175	transmembrane transport
SRIMR7_RS12120	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS12130	COG4249	Peptidase C14 caspase catalytic subunit p20
SRIMR7_RS12130	COG2319	Wd-40 repeat
SRIMR7_RS12140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SRIMR7_RS12150	COG0577	efflux transmembrane transporter activity
SRIMR7_RS12155	COG1295	ribonuclease BN
SRIMR7_RS12160	COG0753	catalase activity
SRIMR7_RS12185	COG0205	6-phosphofructokinase activity
SRIMR7_RS12190	COG0857	belongs to the CobB CobQ family
SRIMR7_RS12190	COG0280	phosphate acetyltransferase
SRIMR7_RS12195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SRIMR7_RS12250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SRIMR7_RS12255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SRIMR7_RS12275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SRIMR7_RS12280	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SRIMR7_RS12280	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SRIMR7_RS12335	COG2205	protein histidine kinase activity
SRIMR7_RS12340	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS12360	COG0183	Belongs to the thiolase family
SRIMR7_RS12380	COG1131	(ABC) transporter
SRIMR7_RS12415	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SRIMR7_RS12430	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIMR7_RS12460	COG3850	Histidine kinase
SRIMR7_RS12465	COG2197	response regulator
SRIMR7_RS12480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SRIMR7_RS12485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SRIMR7_RS12490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SRIMR7_RS12495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SRIMR7_RS12500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SRIMR7_RS12505	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SRIMR7_RS12510	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SRIMR7_RS12530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SRIMR7_RS12535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SRIMR7_RS12545	COG2890	protein-(glutamine-N5) methyltransferase activity
SRIMR7_RS12550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SRIMR7_RS12555	COG0254	rRNA binding
SRIMR7_RS12570	COG0083	homoserine kinase activity
SRIMR7_RS12575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SRIMR7_RS12580	COG0460	homoserine dehydrogenase
SRIMR7_RS12585	COG0019	diaminopimelate decarboxylase activity
SRIMR7_RS12590	COG0018	arginyl-trna synthetase
SRIMR7_RS12595	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS12620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS12650	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS12660	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIMR7_RS12700	COG2124	cytochrome p450
SRIMR7_RS12710	COG0768	penicillin binding
SRIMR7_RS12720	COG1119	ATPase activity
SRIMR7_RS12790	COG1309	transcriptional regulator
SRIMR7_RS12815	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SRIMR7_RS12830	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS12835	COG2205	protein histidine kinase activity
SRIMR7_RS12840	COG0508	dehydrogenase complex catalyzes the overall conversion of
SRIMR7_RS12840	COG0567	Dehydrogenase, E1 component
SRIMR7_RS12945	COG0604	alcohol dehydrogenase
SRIMR7_RS12955	COG0281	malic enzyme
SRIMR7_RS12960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRIMR7_RS12965	COG0765	amino acid transport
SRIMR7_RS12970	COG1126	abc transporter atp-binding protein
SRIMR7_RS12975	COG4106	trans-aconitate 2-methyltransferase activity
SRIMR7_RS12995	COG2201	protein-glutamate methylesterase activity
SRIMR7_RS13030	COG3903	Transcriptional regulator
SRIMR7_RS13030	COG3629	intracellular signal transduction
SRIMR7_RS13060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SRIMR7_RS13065	COG1993	acr, cog1993
SRIMR7_RS13070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SRIMR7_RS13075	COG2186	Transcriptional regulator
SRIMR7_RS13080	COG2807	transmembrane transport
SRIMR7_RS13085	COG0598	Magnesium transport protein CorA
SRIMR7_RS13100	COG0477	Major facilitator Superfamily
SRIMR7_RS13115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIMR7_RS13130	COG2066	Belongs to the glutaminase family
SRIMR7_RS13185	COG1597	lipid kinase activity
SRIMR7_RS13200	COG1309	transcriptional regulator
SRIMR7_RS13205	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS13215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SRIMR7_RS13220	COG0363	glucosamine-6-phosphate deaminase activity
SRIMR7_RS13225	COG1472	Belongs to the glycosyl hydrolase 3 family
SRIMR7_RS13230	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS13235	COG1175	transmembrane transport
SRIMR7_RS13240	COG2182	Extracellular solute-binding protein
SRIMR7_RS13245	COG2188	Transcriptional regulator
SRIMR7_RS13250	COG1966	Carbon starvation protein
SRIMR7_RS13290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SRIMR7_RS13295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRIMR7_RS13300	COG0242	peptide deformylase activity
SRIMR7_RS13310	COG5662	AntiSigma factor
SRIMR7_RS13315	COG1595	DNA-templated transcription, initiation
SRIMR7_RS13320	COG1396	sequence-specific DNA binding
SRIMR7_RS13320	COG3800	Transcriptional regulator
SRIMR7_RS13330	COG2135	peptidase activity
SRIMR7_RS13340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SRIMR7_RS13355	COG2076	Multidrug Resistance protein
SRIMR7_RS13365	COG0483	inositol monophosphate 1-phosphatase activity
SRIMR7_RS13375	COG0753	catalase activity
SRIMR7_RS13405	COG1615	UPF0182 protein
SRIMR7_RS13415	COG3480	Lon protease (S16) C-terminal proteolytic domain
SRIMR7_RS13470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SRIMR7_RS13520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIMR7_RS13525	COG0210	DNA helicase
SRIMR7_RS13570	COG4172	Belongs to the ABC transporter superfamily
SRIMR7_RS13575	COG0601	transmembrane transport
SRIMR7_RS13580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIMR7_RS13595	COG2267	carboxylic ester hydrolase activity
SRIMR7_RS13635	COG1432	Conserved Protein
SRIMR7_RS13645	COG2095	MarC family integral membrane protein
SRIMR7_RS13660	COG2814	Major facilitator Superfamily
SRIMR7_RS13670	COG0598	Magnesium transport protein CorA
SRIMR7_RS13705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SRIMR7_RS13710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRIMR7_RS13720	COG1595	DNA-templated transcription, initiation
SRIMR7_RS13735	COG1024	Enoyl-CoA hydratase
SRIMR7_RS13740	COG0519	Catalyzes the synthesis of GMP from XMP
SRIMR7_RS13750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SRIMR7_RS13760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIMR7_RS13800	COG2197	response regulator
SRIMR7_RS13805	COG4585	Histidine kinase
SRIMR7_RS13815	COG1131	(ABC) transporter
SRIMR7_RS13835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SRIMR7_RS13855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIMR7_RS13860	COG4166	transmembrane transport
SRIMR7_RS13870	COG0444	Belongs to the ABC transporter superfamily
SRIMR7_RS13875	COG4608	Belongs to the ABC transporter superfamily
SRIMR7_RS13885	COG4608	Belongs to the ABC transporter superfamily
SRIMR7_RS13895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIMR7_RS13900	COG0601	transmembrane transport
SRIMR7_RS13930	COG4608	Belongs to the ABC transporter superfamily
SRIMR7_RS13935	COG0444	Belongs to the ABC transporter superfamily
SRIMR7_RS13940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRIMR7_RS13945	COG0601	transmembrane transport
SRIMR7_RS13950	COG4166	transmembrane transport
SRIMR7_RS13955	COG1217	gtp-binding protein TYPA
SRIMR7_RS13975	COG1053	succinate dehydrogenase
SRIMR7_RS14005	COG0531	amino acid
SRIMR7_RS14020	COG0596	Alpha beta hydrolase
SRIMR7_RS14020	COG0508	dehydrogenase complex catalyzes the overall conversion of
SRIMR7_RS14050	COG0012	GTP binding
SRIMR7_RS14065	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SRIMR7_RS14075	COG1570	exodeoxyribonuclease VII activity
SRIMR7_RS14080	COG1722	exodeoxyribonuclease VII activity
SRIMR7_RS14085	COG0778	Nitroreductase
SRIMR7_RS14110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SRIMR7_RS14110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SRIMR7_RS14115	COG0114	fumarate hydratase activity
SRIMR7_RS14140	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SRIMR7_RS14155	COG1136	(ABC) transporter
SRIMR7_RS14170	COG1136	(ABC) transporter
SRIMR7_RS14195	COG0450	alkyl hydroperoxide reductase
SRIMR7_RS14200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIMR7_RS14220	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SRIMR7_RS14225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SRIMR7_RS14230	COG0667	Aldo Keto reductase
SRIMR7_RS14275	COG2885	chlorophyll binding
SRIMR7_RS14320	COG2894	cell division
SRIMR7_RS14375	COG2610	gluconate transmembrane transporter activity
SRIMR7_RS14380	COG0251	oxidation-reduction process
SRIMR7_RS14385	COG1414	Transcriptional regulator
SRIMR7_RS14400	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SRIMR7_RS14420	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SRIMR7_RS14435	COG0789	Transcriptional regulator
SRIMR7_RS14445	COG1331	Highly conserved protein containing a thioredoxin domain
SRIMR7_RS14465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SRIMR7_RS14475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SRIMR7_RS14490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SRIMR7_RS14495	COG2255	four-way junction helicase activity
SRIMR7_RS14500	COG1595	DNA-templated transcription, initiation
SRIMR7_RS14520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SRIMR7_RS14575	COG2986	histidine ammonia-lyase
SRIMR7_RS14585	COG1024	Enoyl-CoA hydratase
SRIMR7_RS14590	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SRIMR7_RS14600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SRIMR7_RS14615	COG0768	penicillin binding
SRIMR7_RS14620	COG0424	maF-like protein
SRIMR7_RS14660	COG4770	biotin carboxylase activity
SRIMR7_RS14665	COG0702	epimerase
SRIMR7_RS14700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SRIMR7_RS14735	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS14740	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS14755	COG1595	DNA-templated transcription, initiation
SRIMR7_RS14760	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS14765	COG2205	protein histidine kinase activity
SRIMR7_RS14790	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SRIMR7_RS14805	COG0583	DNA-binding transcription factor activity
SRIMR7_RS14810	COG2814	Major facilitator Superfamily
SRIMR7_RS14840	COG1079	Belongs to the binding-protein-dependent transport system permease family
SRIMR7_RS14845	COG4603	Belongs to the binding-protein-dependent transport system permease family
SRIMR7_RS14850	COG3845	ABC transporter
SRIMR7_RS14855	COG1744	ABC transporter substrate-binding protein PnrA-like
SRIMR7_RS14860	COG1473	amidohydrolase
SRIMR7_RS14860	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SRIMR7_RS14870	COG2089	acid synthase
SRIMR7_RS14875	COG1083	cytidylyl-transferase
SRIMR7_RS14885	COG1216	Glycosyl transferase, family 2
SRIMR7_RS14895	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SRIMR7_RS14930	COG3265	gluconokinase activity
SRIMR7_RS14935	COG2186	Transcriptional regulator
SRIMR7_RS14960	COG3961	Belongs to the TPP enzyme family
SRIMR7_RS14965	COG1846	Transcriptional regulator
SRIMR7_RS14990	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SRIMR7_RS15000	COG2009	succinate dehydrogenase
SRIMR7_RS15010	COG1053	succinate dehydrogenase
SRIMR7_RS15015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SRIMR7_RS15035	COG1309	transcriptional regulator
SRIMR7_RS15045	COG1404	Belongs to the peptidase S8 family
SRIMR7_RS15070	COG1295	ribonuclease BN
SRIMR7_RS15080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SRIMR7_RS15105	COG0180	Tryptophanyl-tRNA synthetase
SRIMR7_RS15115	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SRIMR7_RS15120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRIMR7_RS15125	COG0754	glutathionylspermidine amidase activity
SRIMR7_RS15140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIMR7_RS15145	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIMR7_RS15150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIMR7_RS15175	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SRIMR7_RS15180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIMR7_RS15190	COG1396	sequence-specific DNA binding
SRIMR7_RS15205	COG2197	response regulator
SRIMR7_RS15220	COG4585	Histidine kinase
SRIMR7_RS15230	COG4176	ABC-type proline glycine betaine transport system permease component
SRIMR7_RS15240	COG4175	Glycine betaine
SRIMR7_RS15240	COG0517	IMP dehydrogenase activity
SRIMR7_RS15250	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS15275	COG1476	TRANSCRIPTIONal
SRIMR7_RS15300	COG0039	L-malate dehydrogenase activity
SRIMR7_RS15335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SRIMR7_RS15340	COG1714	RDD family
SRIMR7_RS15350	COG0138	bifunctional purine biosynthesis protein purh
SRIMR7_RS15380	COG0045	succinate-CoA ligase (ADP-forming) activity
SRIMR7_RS15395	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SRIMR7_RS15400	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SRIMR7_RS15405	COG0714	Associated with various cellular activities
SRIMR7_RS15420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SRIMR7_RS15465	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS15490	COG0789	Transcriptional regulator
SRIMR7_RS15520	COG1309	transcriptional regulator
SRIMR7_RS15530	COG2197	response regulator
SRIMR7_RS15545	COG0515	serine threonine protein kinase
SRIMR7_RS15545	COG2815	serine threonine protein kinase
SRIMR7_RS15590	COG2084	Dehydrogenase
SRIMR7_RS15605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SRIMR7_RS15605	COG0519	Catalyzes the synthesis of GMP from XMP
SRIMR7_RS15625	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS15630	COG0515	serine threonine protein kinase
SRIMR7_RS15645	COG2197	response regulator
SRIMR7_RS15650	COG4585	Histidine kinase
SRIMR7_RS15700	COG1131	(ABC) transporter
SRIMR7_RS15730	COG4821	SIS domain
SRIMR7_RS15740	COG0259	pyridoxamine-phosphate oxidase activity
SRIMR7_RS15760	COG1309	transcriptional regulator
SRIMR7_RS15765	COG1024	Enoyl-CoA hydratase
SRIMR7_RS15770	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS15785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SRIMR7_RS15820	COG2124	cytochrome p450
SRIMR7_RS15830	COG5006	permease, DMT superfamily
SRIMR7_RS15835	COG0583	DNA-binding transcription factor activity
SRIMR7_RS15840	COG0247	lactate metabolic process
SRIMR7_RS15840	COG0277	FAD linked oxidase domain protein
SRIMR7_RS15850	COG2378	regulation of single-species biofilm formation
SRIMR7_RS15855	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SRIMR7_RS15890	COG0667	Aldo Keto reductase
SRIMR7_RS15925	COG2252	PERMEase
SRIMR7_RS15935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SRIMR7_RS15955	COG2814	Major facilitator Superfamily
SRIMR7_RS15965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SRIMR7_RS15970	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SRIMR7_RS15990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS15995	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS16000	COG1120	ATPase activity
SRIMR7_RS16005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SRIMR7_RS16025	COG1061	Type III restriction enzyme res subunit
SRIMR7_RS16040	COG3973	AAA domain
SRIMR7_RS16045	COG3142	Participates in the control of copper homeostasis
SRIMR7_RS16080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SRIMR7_RS16085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SRIMR7_RS16095	COG1115	amino acid carrier protein
SRIMR7_RS16100	COG4221	oxidoreductase activity
SRIMR7_RS16110	COG1278	Cold shock
SRIMR7_RS16125	COG0463	Glycosyl transferase, family 2
SRIMR7_RS16150	COG1940	carbohydrate kinase activity
SRIMR7_RS16155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SRIMR7_RS16180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SRIMR7_RS16230	COG2207	Transcriptional regulator
SRIMR7_RS16230	COG3708	Transcriptional regulator
SRIMR7_RS16245	COG3842	ATPase activity
SRIMR7_RS16255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SRIMR7_RS16270	COG0215	cysteine-tRNA ligase activity
SRIMR7_RS16275	COG3467	pyridoxamine 5'-phosphate
SRIMR7_RS16280	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SRIMR7_RS16285	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SRIMR7_RS16290	COG1329	Transcriptional regulator
SRIMR7_RS16305	COG5002	protein histidine kinase activity
SRIMR7_RS16320	COG0367	asparagine synthase
SRIMR7_RS16325	COG0588	phosphoglycerate mutase activity
SRIMR7_RS16340	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS16355	COG0667	Aldo Keto reductase
SRIMR7_RS16375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SRIMR7_RS16395	COG0456	acetyltransferase
SRIMR7_RS16400	COG0737	Belongs to the 5'-nucleotidase family
SRIMR7_RS16445	COG0702	epimerase
SRIMR7_RS16460	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS16470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRIMR7_RS16475	COG1609	Transcriptional regulator
SRIMR7_RS16480	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS16515	COG2897	thiosulfate sulfurtransferase activity
SRIMR7_RS16535	COG3485	protocatechuate 3,4-dioxygenase
SRIMR7_RS16540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS16545	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SRIMR7_RS16555	COG0735	belongs to the Fur family
SRIMR7_RS16560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SRIMR7_RS16565	COG1490	D-aminoacyl-tRNA deacylase activity
SRIMR7_RS16580	COG4552	Acetyltransferase involved in intracellular survival and related
SRIMR7_RS16595	COG1733	regulation of RNA biosynthetic process
SRIMR7_RS16610	COG2890	protein-(glutamine-N5) methyltransferase activity
SRIMR7_RS16620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SRIMR7_RS16640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SRIMR7_RS16650	COG1733	regulation of RNA biosynthetic process
SRIMR7_RS16655	COG0604	alcohol dehydrogenase
SRIMR7_RS16690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SRIMR7_RS16710	COG0306	phosphate transporter
SRIMR7_RS16720	COG1937	Protein conserved in bacteria
SRIMR7_RS16740	COG0277	FAD linked oxidase domain protein
SRIMR7_RS16750	COG0671	phosphoesterase, PA-phosphatase related
SRIMR7_RS16755	COG0791	NLP P60 protein
SRIMR7_RS16835	COG0180	Tryptophanyl-tRNA synthetase
SRIMR7_RS16840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SRIMR7_RS16860	COG0659	secondary active sulfate transmembrane transporter activity
SRIMR7_RS16865	COG0308	aminopeptidase N
SRIMR7_RS16870	COG2226	methyltransferase
SRIMR7_RS16900	COG0129	dihydroxy-acid dehydratase activity
SRIMR7_RS16910	COG1082	Xylose isomerase domain protein TIM barrel
SRIMR7_RS16915	COG0248	Ppx GppA phosphatase
SRIMR7_RS16935	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SRIMR7_RS16950	COG0671	phosphoesterase, PA-phosphatase related
SRIMR7_RS16960	COG1194	a g-specific adenine glycosylase
SRIMR7_RS16965	COG1595	DNA-templated transcription, initiation
SRIMR7_RS16975	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS16980	COG2205	protein histidine kinase activity
SRIMR7_RS16985	COG0346	lactoylglutathione lyase activity
SRIMR7_RS16990	COG2207	Transcriptional regulator
SRIMR7_RS16990	COG4753	response regulator
SRIMR7_RS16995	COG0477	Major facilitator Superfamily
SRIMR7_RS17005	COG0741	lytic transglycosylase activity
SRIMR7_RS17005	COG1196	nuclear chromosome segregation
SRIMR7_RS17005	COG0739	heme binding
SRIMR7_RS17030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SRIMR7_RS17050	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SRIMR7_RS17060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SRIMR7_RS17065	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SRIMR7_RS17080	COG0640	Transcriptional regulator
SRIMR7_RS17110	COG0649	NAD binding
SRIMR7_RS17125	COG3226	Transcriptional regulator
SRIMR7_RS17135	COG1309	transcriptional regulator
SRIMR7_RS17140	COG2814	Major facilitator Superfamily
SRIMR7_RS17150	COG1732	Glycine betaine
SRIMR7_RS17155	COG1174	glycine betaine transport
SRIMR7_RS17160	COG1174	glycine betaine transport
SRIMR7_RS17165	COG1125	glycine betaine transport
SRIMR7_RS17165	COG0517	IMP dehydrogenase activity
SRIMR7_RS17175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SRIMR7_RS17180	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SRIMR7_RS17195	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SRIMR7_RS17195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SRIMR7_RS17205	COG0302	gtp cyclohydrolase
SRIMR7_RS17220	COG0037	tRNA processing
SRIMR7_RS17230	COG2027	D-alanyl-D-alanine carboxypeptidase
SRIMR7_RS17235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SRIMR7_RS17250	COG0393	Putative heavy-metal-binding
SRIMR7_RS17255	COG0789	Transcriptional regulator
SRIMR7_RS17295	COG0655	NAD(P)H dehydrogenase (quinone) activity
SRIMR7_RS17300	COG0076	glutamate decarboxylase activity
SRIMR7_RS17320	COG2318	DinB family
SRIMR7_RS17325	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS17345	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SRIMR7_RS17355	COG0254	rRNA binding
SRIMR7_RS17365	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SRIMR7_RS17370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SRIMR7_RS17380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SRIMR7_RS17380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SRIMR7_RS17395	COG3655	Transcriptional regulator
SRIMR7_RS17400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SRIMR7_RS17400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SRIMR7_RS17405	COG0657	acetylesterase activity
SRIMR7_RS17410	COG1309	transcriptional regulator
SRIMR7_RS17420	COG1349	DNA-binding transcription factor activity
SRIMR7_RS17455	COG2197	response regulator
SRIMR7_RS17460	COG0584	glycerophosphoryl diester phosphodiesterase
SRIMR7_RS17485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SRIMR7_RS17495	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
SRIMR7_RS17510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS17525	COG1132	(ABC) transporter
SRIMR7_RS17530	COG2366	antibiotic biosynthetic process
SRIMR7_RS17545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SRIMR7_RS17550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SRIMR7_RS17560	COG1754	DNA topoisomerase type I activity
SRIMR7_RS17560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SRIMR7_RS17580	COG2890	protein-(glutamine-N5) methyltransferase activity
SRIMR7_RS17590	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SRIMR7_RS17600	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIMR7_RS17605	COG1111	helicase
SRIMR7_RS17605	COG1205	dead DEAH box helicase
SRIMR7_RS17615	COG1917	Cupin 2, conserved barrel domain protein
SRIMR7_RS17680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SRIMR7_RS17685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SRIMR7_RS17695	COG2267	carboxylic ester hydrolase activity
SRIMR7_RS17725	COG2957	Belongs to the agmatine deiminase family
SRIMR7_RS17735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SRIMR7_RS17760	COG0003	Pfam Anion-transporting ATPase
SRIMR7_RS17770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRIMR7_RS17780	COG1408	metallophosphoesterase
SRIMR7_RS17825	COG2268	Band 7 protein
SRIMR7_RS17830	COG4106	trans-aconitate 2-methyltransferase activity
SRIMR7_RS17845	COG1819	glycosyl
SRIMR7_RS17855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIMR7_RS17860	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS17865	COG2030	dehydratase
SRIMR7_RS17880	COG0515	serine threonine protein kinase
SRIMR7_RS17885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIMR7_RS17895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIMR7_RS17950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SRIMR7_RS18000	COG1357	PFAM Pentapeptide repeats (8 copies)
SRIMR7_RS18015	COG1595	DNA-templated transcription, initiation
SRIMR7_RS18035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SRIMR7_RS18040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SRIMR7_RS18075	COG2249	NAD(P)H dehydrogenase (quinone) activity
SRIMR7_RS18080	COG1595	DNA-templated transcription, initiation
SRIMR7_RS18100	COG0402	S-adenosylhomocysteine deaminase activity
SRIMR7_RS18130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SRIMR7_RS18135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SRIMR7_RS18140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SRIMR7_RS18145	COG1609	Transcriptional regulator
SRIMR7_RS18155	COG1309	transcriptional regulator
SRIMR7_RS18170	COG0488	(ABC) transporter
SRIMR7_RS18185	COG4552	Acetyltransferase involved in intracellular survival and related
SRIMR7_RS18190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SRIMR7_RS18195	COG0463	Glycosyl transferase, family 2
SRIMR7_RS18205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRIMR7_RS18225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIMR7_RS18235	COG1940	carbohydrate kinase activity
SRIMR7_RS18280	COG0523	cobalamin synthesis protein
SRIMR7_RS18315	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SRIMR7_RS18340	COG0657	acetylesterase activity
SRIMR7_RS18365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SRIMR7_RS18380	COG0640	Transcriptional regulator
SRIMR7_RS18395	COG1191	sigma factor activity
SRIMR7_RS18400	COG1191	sigma factor activity
SRIMR7_RS18410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS18430	COG1595	DNA-templated transcription, initiation
SRIMR7_RS18465	COG0110	maltose O-acetyltransferase activity
SRIMR7_RS18515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SRIMR7_RS18525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS18565	COG0477	Major facilitator Superfamily
SRIMR7_RS18570	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SRIMR7_RS18580	COG2205	protein histidine kinase activity
SRIMR7_RS18585	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS18610	COG2249	NAD(P)H dehydrogenase (quinone) activity
SRIMR7_RS18635	COG1609	Transcriptional regulator
SRIMR7_RS18715	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS18760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS18770	COG1595	DNA-templated transcription, initiation
SRIMR7_RS18805	COG0457	Tetratricopeptide repeat
SRIMR7_RS18830	COG2188	Transcriptional regulator
SRIMR7_RS18965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRIMR7_RS19005	COG0006	proline dipeptidase activity
SRIMR7_RS19040	COG2372	response to copper ion
SRIMR7_RS19045	COG2837	iron assimilation
SRIMR7_RS19055	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SRIMR7_RS19060	COG0561	phosphatase activity
SRIMR7_RS19090	COG0789	Transcriptional regulator
SRIMR7_RS19105	COG2186	Transcriptional regulator
SRIMR7_RS19110	COG2807	transmembrane transport
SRIMR7_RS19120	COG0789	Transcriptional regulator
SRIMR7_RS19160	COG1131	(ABC) transporter
SRIMR7_RS19180	COG0789	Transcriptional regulator
SRIMR7_RS19195	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SRIMR7_RS19225	COG0501	Belongs to the peptidase M48B family
SRIMR7_RS19235	COG0561	phosphatase activity
SRIMR7_RS19240	COG0739	heme binding
SRIMR7_RS19250	COG4988	ABC transporter
SRIMR7_RS19255	COG1294	oxidase, subunit
SRIMR7_RS19260	COG1271	oxidase subunit
SRIMR7_RS19270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SRIMR7_RS19275	COG1609	Transcriptional regulator
SRIMR7_RS19280	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SRIMR7_RS19300	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SRIMR7_RS19325	COG0662	Cupin 2, conserved barrel domain protein
SRIMR7_RS19330	COG1950	PFAM Membrane protein of
SRIMR7_RS19335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SRIMR7_RS19340	COG0626	cystathionine gamma-synthase activity
SRIMR7_RS19380	COG2814	Major facilitator Superfamily
SRIMR7_RS19385	COG1846	Transcriptional regulator
SRIMR7_RS19420	COG4978	Transcriptional regulator
SRIMR7_RS19420	COG0789	Transcriptional regulator
SRIMR7_RS19445	COG0242	peptide deformylase activity
SRIMR7_RS19450	COG1309	transcriptional regulator
SRIMR7_RS19465	COG0305	Participates in initiation and elongation during chromosome replication
SRIMR7_RS19470	COG0534	Mate efflux family protein
SRIMR7_RS19480	COG0359	binds to the 23S rRNA
SRIMR7_RS19485	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SRIMR7_RS19490	COG0629	single-stranded DNA binding
SRIMR7_RS19495	COG0360	Binds together with S18 to 16S ribosomal RNA
SRIMR7_RS19520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRIMR7_RS19525	COG1695	Transcriptional regulator
SRIMR7_RS19545	COG0617	tRNA 3'-terminal CCA addition
SRIMR7_RS19570	COG1595	DNA-templated transcription, initiation
SRIMR7_RS19580	COG0492	ferredoxin-NADP+ reductase activity
SRIMR7_RS19585	COG3118	belongs to the thioredoxin family
SRIMR7_RS19600	COG1192	Involved in chromosome partitioning
SRIMR7_RS19605	COG0357	Ribosomal RNA small subunit methyltransferase G
SRIMR7_RS19615	COG0706	membrane insertase activity
SRIMR7_RS19620	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SRIMR7_RS19630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SRIMR7_RS19635	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SRIMR7_RS19640	COG0592	DNA-directed DNA polymerase activity
SRIMR7_RS19645	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SRIMR7_RS19650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SRIMR7_RS19655	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SRIMR7_RS19665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SRIMR7_RS19690	COG0515	serine threonine protein kinase
SRIMR7_RS19715	COG0705	Rhomboid family
SRIMR7_RS19730	COG3764	Sortase (surface protein transpeptidase)
SRIMR7_RS19745	COG3764	Sortase (surface protein transpeptidase)
SRIMR7_RS19750	COG3764	Sortase (surface protein transpeptidase)
SRIMR7_RS19755	COG0515	serine threonine protein kinase
SRIMR7_RS19760	COG0768	penicillin binding
SRIMR7_RS19775	COG1716	ATPase activity
SRIMR7_RS19780	COG1716	ATPase activity
SRIMR7_RS19790	COG0583	DNA-binding transcription factor activity
SRIMR7_RS19800	COG4585	Histidine kinase
SRIMR7_RS19805	COG2197	response regulator
SRIMR7_RS19810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SRIMR7_RS19815	COG1733	regulation of RNA biosynthetic process
SRIMR7_RS19850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SRIMR7_RS19855	COG2151	metal-sulfur cluster biosynthetic enzyme
SRIMR7_RS19860	COG3396	Phenylacetate-CoA oxygenase
SRIMR7_RS19865	COG3460	Phenylacetate-CoA oxygenase
SRIMR7_RS19870	COG3396	Phenylacetate-CoA oxygenase
SRIMR7_RS19895	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRIMR7_RS19900	COG1309	transcriptional regulator
SRIMR7_RS19905	COG1522	sequence-specific DNA binding
SRIMR7_RS19925	COG0746	molybdenum cofactor guanylyltransferase activity
SRIMR7_RS19930	COG0303	'Molybdopterin
SRIMR7_RS19935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SRIMR7_RS19940	COG3321	synthase
SRIMR7_RS19940	COG0604	alcohol dehydrogenase
SRIMR7_RS19940	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS19955	COG0515	serine threonine protein kinase
SRIMR7_RS19960	COG0515	serine threonine protein kinase
SRIMR7_RS19985	COG0022	dehydrogenase e1 component
SRIMR7_RS19990	COG0508	dehydrogenase complex catalyzes the overall conversion of
SRIMR7_RS20045	COG0477	Major facilitator Superfamily
SRIMR7_RS20070	COG1802	Transcriptional regulator
SRIMR7_RS20135	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS20150	COG3629	intracellular signal transduction
SRIMR7_RS20150	COG3903	Transcriptional regulator
SRIMR7_RS20155	COG1362	aminopeptidase activity
SRIMR7_RS20160	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS20175	COG1741	Belongs to the pirin family
SRIMR7_RS20180	COG0628	permease
SRIMR7_RS20190	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SRIMR7_RS20205	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SRIMR7_RS20210	COG2226	methyltransferase
SRIMR7_RS20235	COG1174	glycine betaine transport
SRIMR7_RS20240	COG1174	glycine betaine transport
SRIMR7_RS20250	COG0517	IMP dehydrogenase activity
SRIMR7_RS20250	COG1125	glycine betaine transport
SRIMR7_RS20340	COG1316	TRANSCRIPTIONal
SRIMR7_RS20380	COG0477	Major facilitator Superfamily
SRIMR7_RS20400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIMR7_RS20415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIMR7_RS20430	COG2197	response regulator
SRIMR7_RS20440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIMR7_RS20450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS20470	COG3629	intracellular signal transduction
SRIMR7_RS20480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SRIMR7_RS20495	COG0789	Transcriptional regulator
SRIMR7_RS20510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS20510	COG3321	synthase
SRIMR7_RS20535	COG5635	Nacht domain
SRIMR7_RS20535	COG2319	Wd-40 repeat
SRIMR7_RS20590	COG0717	Belongs to the dCTP deaminase family
SRIMR7_RS20625	COG2181	nitrate reductase activity
SRIMR7_RS20625	COG0247	lactate metabolic process
SRIMR7_RS20630	COG0443	Heat shock 70 kDa protein
SRIMR7_RS20635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SRIMR7_RS20640	COG0484	heat shock protein binding
SRIMR7_RS20645	COG0789	Transcriptional regulator
SRIMR7_RS20665	COG0542	response to heat
SRIMR7_RS20700	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SRIMR7_RS20715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SRIMR7_RS20720	COG0191	fructose-bisphosphate aldolase activity
SRIMR7_RS20730	COG3483	tryptophan 2,3-dioxygenase activity
SRIMR7_RS20735	COG3844	kynureninase activity
SRIMR7_RS20740	COG0657	acetylesterase activity
SRIMR7_RS20745	COG4585	Histidine kinase
SRIMR7_RS20750	COG2197	response regulator
SRIMR7_RS20765	COG3559	Exporter of polyketide antibiotics
SRIMR7_RS20770	COG1131	(ABC) transporter
SRIMR7_RS20785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SRIMR7_RS20800	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SRIMR7_RS20825	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SRIMR7_RS20845	COG0693	protein deglycase activity
SRIMR7_RS20855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SRIMR7_RS20860	COG1802	Transcriptional regulator
SRIMR7_RS20910	COG0151	Belongs to the GarS family
SRIMR7_RS20925	COG0583	DNA-binding transcription factor activity
SRIMR7_RS20930	COG2814	Major facilitator Superfamily
SRIMR7_RS20935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SRIMR7_RS20950	COG3850	Histidine kinase
SRIMR7_RS20985	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SRIMR7_RS20990	COG0047	phosphoribosylformylglycinamidine synthase activity
SRIMR7_RS20995	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SRIMR7_RS21055	COG1643	Atp-dependent helicase
SRIMR7_RS21090	COG0513	Belongs to the DEAD box helicase family
SRIMR7_RS21140	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SRIMR7_RS21215	COG2814	Major facilitator Superfamily
SRIMR7_RS21220	COG0667	Aldo Keto reductase
SRIMR7_RS21260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SRIMR7_RS21265	COG0579	oxidoreductase
SRIMR7_RS21290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIMR7_RS21325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SRIMR7_RS21330	COG0123	including yeast histone deacetylase and acetoin utilization protein
SRIMR7_RS21385	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SRIMR7_RS21390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SRIMR7_RS21395	COG0181	hydroxymethylbilane synthase activity
SRIMR7_RS21400	COG1648	precorrin-2 dehydrogenase activity
SRIMR7_RS21400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SRIMR7_RS21405	COG0113	porphobilinogen synthase activity
SRIMR7_RS21440	COG2814	Major facilitator Superfamily
SRIMR7_RS21465	COG0018	arginyl-trna synthetase
SRIMR7_RS21470	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SRIMR7_RS21535	COG1690	Belongs to the RtcB family
SRIMR7_RS21555	COG1742	UPF0060 membrane protein
SRIMR7_RS21565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SRIMR7_RS21580	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS21595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRIMR7_RS21605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SRIMR7_RS21610	COG0406	alpha-ribazole phosphatase activity
SRIMR7_RS21625	COG0785	Cytochrome C biogenesis protein
SRIMR7_RS21630	COG1333	cytochrome c biogenesis protein
SRIMR7_RS21635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SRIMR7_RS21680	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SRIMR7_RS21685	COG0109	protoheme IX farnesyltransferase activity
SRIMR7_RS21700	COG0163	prenyltransferase activity
SRIMR7_RS21715	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SRIMR7_RS21730	COG1823	symporter activity
SRIMR7_RS21745	COG1309	transcriptional regulator
SRIMR7_RS21770	COG1278	Cold shock
SRIMR7_RS21775	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SRIMR7_RS21780	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SRIMR7_RS21790	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SRIMR7_RS21805	COG2226	methyltransferase
SRIMR7_RS21845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIMR7_RS21850	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIMR7_RS21855	COG0649	NAD binding
SRIMR7_RS21865	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SRIMR7_RS21870	COG1034	ATP synthesis coupled electron transport
SRIMR7_RS21875	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SRIMR7_RS21880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIMR7_RS21885	COG0839	Belongs to the complex I subunit 6 family
SRIMR7_RS21890	COG0713	ATP synthesis coupled electron transport
SRIMR7_RS21895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SRIMR7_RS21905	COG1007	ATP synthesis coupled electron transport
SRIMR7_RS21935	COG0492	ferredoxin-NADP+ reductase activity
SRIMR7_RS21940	COG0142	geranyltranstransferase activity
SRIMR7_RS21960	COG4935	Belongs to the peptidase S8 family
SRIMR7_RS21960	COG2234	aminopeptidase activity
SRIMR7_RS21970	COG1013	pyruvate-flavodoxin oxidoreductase activity
SRIMR7_RS21975	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SRIMR7_RS21975	COG0674	pyruvate-flavodoxin oxidoreductase activity
SRIMR7_RS21985	COG4585	Histidine kinase
SRIMR7_RS21990	COG4585	Histidine kinase
SRIMR7_RS22010	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIMR7_RS22015	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIMR7_RS22020	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIMR7_RS22025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SRIMR7_RS22030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SRIMR7_RS22035	COG0839	Belongs to the complex I subunit 6 family
SRIMR7_RS22040	COG0713	ATP synthesis coupled electron transport
SRIMR7_RS22045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SRIMR7_RS22055	COG1007	ATP synthesis coupled electron transport
SRIMR7_RS22060	COG0501	Belongs to the peptidase M48B family
SRIMR7_RS22065	COG3304	Inner membrane component domain
SRIMR7_RS22075	COG1666	GTP binding
SRIMR7_RS22085	COG0702	epimerase
SRIMR7_RS22105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SRIMR7_RS22110	COG2030	dehydratase
SRIMR7_RS22120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SRIMR7_RS22125	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SRIMR7_RS22130	COG0436	Aminotransferase
SRIMR7_RS22150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SRIMR7_RS22155	COG0081	regulation of translation
SRIMR7_RS22165	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SRIMR7_RS22170	COG0222	ribosome binding
SRIMR7_RS22175	COG0085	RNA polymerase activity
SRIMR7_RS22180	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SRIMR7_RS22190	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SRIMR7_RS22195	COG0049	tRNA binding
SRIMR7_RS22200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SRIMR7_RS22205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SRIMR7_RS22210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SRIMR7_RS22235	COG0051	transcription antitermination factor activity, RNA binding
SRIMR7_RS22240	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SRIMR7_RS22245	COG0088	Forms part of the polypeptide exit tunnel
SRIMR7_RS22250	COG0089	rRNA binding
SRIMR7_RS22255	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SRIMR7_RS22260	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SRIMR7_RS22265	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SRIMR7_RS22270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SRIMR7_RS22275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SRIMR7_RS22280	COG0255	Belongs to the universal ribosomal protein uL29 family
SRIMR7_RS22285	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SRIMR7_RS22290	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SRIMR7_RS22295	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SRIMR7_RS22300	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SRIMR7_RS22305	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SRIMR7_RS22310	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SRIMR7_RS22315	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SRIMR7_RS22320	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SRIMR7_RS22325	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SRIMR7_RS22330	COG1841	ribosomal large subunit assembly
SRIMR7_RS22335	COG0200	Binds to the 23S rRNA
SRIMR7_RS22345	COG0563	adenylate kinase activity
SRIMR7_RS22355	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SRIMR7_RS22360	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SRIMR7_RS22365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SRIMR7_RS22370	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SRIMR7_RS22375	COG0202	RNA polymerase activity
SRIMR7_RS22380	COG0203	ribosomal protein L17
SRIMR7_RS22385	COG0101	tRNA pseudouridine synthase activity
SRIMR7_RS22395	COG0488	(ABC) transporter
SRIMR7_RS22405	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SRIMR7_RS22410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SRIMR7_RS22415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SRIMR7_RS22425	COG1072	(Pantothenic acid kinase))
SRIMR7_RS22430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SRIMR7_RS22435	COG0736	holo-[acyl-carrier-protein] synthase activity
SRIMR7_RS22445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SRIMR7_RS22455	COG0802	atpase or kinase
SRIMR7_RS22480	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SRIMR7_RS22500	COG0772	Belongs to the SEDS family
SRIMR7_RS22505	COG1316	TRANSCRIPTIONal
SRIMR7_RS22510	COG2205	protein histidine kinase activity
SRIMR7_RS22515	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS22520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SRIMR7_RS22525	COG0459	protein refolding
SRIMR7_RS22550	COG1609	Transcriptional regulator
SRIMR7_RS22560	COG4221	oxidoreductase activity
SRIMR7_RS22570	COG0583	DNA-binding transcription factor activity
SRIMR7_RS22580	COG2197	response regulator
SRIMR7_RS22585	COG1595	DNA-templated transcription, initiation
SRIMR7_RS22600	COG0516	GMP reductase activity
SRIMR7_RS22615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SRIMR7_RS22635	COG0477	Major facilitator Superfamily
SRIMR7_RS22640	COG0583	DNA-binding transcription factor activity
SRIMR7_RS22650	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS22655	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS22670	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS22675	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS22685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SRIMR7_RS22690	COG1024	Enoyl-CoA hydratase
SRIMR7_RS22700	COG2072	flavoprotein involved in K transport
SRIMR7_RS22805	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS22815	COG1309	transcriptional regulator
SRIMR7_RS22825	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SRIMR7_RS22825	COG0515	serine threonine protein kinase
SRIMR7_RS22845	COG1024	Enoyl-CoA hydratase
SRIMR7_RS22920	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SRIMR7_RS22940	COG0492	ferredoxin-NADP+ reductase activity
SRIMR7_RS22980	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SRIMR7_RS23030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIMR7_RS23055	COG1686	Belongs to the peptidase S11 family
SRIMR7_RS23065	COG0640	Transcriptional regulator
SRIMR7_RS23090	COG2205	protein histidine kinase activity
SRIMR7_RS23120	COG0514	ATP-dependent DNA helicase (RecQ)
SRIMR7_RS23140	COG1595	DNA-templated transcription, initiation
SRIMR7_RS23390	COG1674	ftsk spoiiie
SRIMR7_RS23575	COG5280	Phage tail tape measure protein TP901
SRIMR7_RS23575	COG3953	SLT domain
SRIMR7_RS23660	COG0659	secondary active sulfate transmembrane transporter activity
SRIMR7_RS23675	COG0477	Major facilitator Superfamily
SRIMR7_RS23745	COG1309	transcriptional regulator
SRIMR7_RS23780	COG1846	Transcriptional regulator
SRIMR7_RS23800	COG1247	-acetyltransferase
SRIMR7_RS23810	COG1349	DNA-binding transcription factor activity
SRIMR7_RS23830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIMR7_RS23845	COG3191	aminopeptidase activity
SRIMR7_RS23860	COG1473	amidohydrolase
SRIMR7_RS23885	COG0730	response to heat
SRIMR7_RS23890	COG2188	Transcriptional regulator
SRIMR7_RS23895	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SRIMR7_RS23900	COG0477	Major facilitator Superfamily
SRIMR7_RS23925	COG1970	mechanosensitive ion channel activity
SRIMR7_RS23935	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SRIMR7_RS23945	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SRIMR7_RS23950	COG3263	regulation of cellular component size
SRIMR7_RS23955	COG2366	antibiotic biosynthetic process
SRIMR7_RS23960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SRIMR7_RS23965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SRIMR7_RS23975	COG0315	cyclic pyranopterin monophosphate synthase activity
SRIMR7_RS23980	COG0521	Mo-molybdopterin cofactor biosynthetic process
SRIMR7_RS23985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SRIMR7_RS24005	COG0739	heme binding
SRIMR7_RS24010	COG1609	Transcriptional regulator
SRIMR7_RS24020	COG1175	transmembrane transport
SRIMR7_RS24025	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS24045	COG1819	glycosyl
SRIMR7_RS24050	COG0789	Transcriptional regulator
SRIMR7_RS24060	COG2205	protein histidine kinase activity
SRIMR7_RS24080	COG0708	Exodeoxyribonuclease III
SRIMR7_RS24145	COG1733	regulation of RNA biosynthetic process
SRIMR7_RS24150	COG0251	oxidation-reduction process
SRIMR7_RS24155	COG1335	isochorismatase
SRIMR7_RS24165	COG2072	flavoprotein involved in K transport
SRIMR7_RS24170	COG2267	carboxylic ester hydrolase activity
SRIMR7_RS24175	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS24190	COG4946	Tricorn protease homolog
SRIMR7_RS24190	COG0793	Belongs to the peptidase S41A family
SRIMR7_RS24200	COG2409	Drug exporters of the RND superfamily
SRIMR7_RS24215	COG0310	cobalt ion transport
SRIMR7_RS24225	COG1122	ATPase activity
SRIMR7_RS24230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRIMR7_RS24240	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS24250	COG0768	penicillin binding
SRIMR7_RS24275	COG0084	hydrolase, TatD family'
SRIMR7_RS24280	COG3583	domain protein
SRIMR7_RS24280	COG3584	3D domain protein
SRIMR7_RS24285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SRIMR7_RS24290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SRIMR7_RS24300	COG0488	(ABC) transporter
SRIMR7_RS24330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SRIMR7_RS24335	COG2197	response regulator
SRIMR7_RS24355	COG4106	trans-aconitate 2-methyltransferase activity
SRIMR7_RS24365	COG1309	transcriptional regulator
SRIMR7_RS24375	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SRIMR7_RS24390	COG0193	aminoacyl-tRNA hydrolase activity
SRIMR7_RS24395	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SRIMR7_RS24400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SRIMR7_RS24405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SRIMR7_RS24420	COG4585	Histidine kinase
SRIMR7_RS24445	COG1316	TRANSCRIPTIONal
SRIMR7_RS24455	COG2814	Major facilitator Superfamily
SRIMR7_RS24470	COG3896	Chloramphenicol phosphotransferase-like protein
SRIMR7_RS24495	COG2814	Major facilitator Superfamily
SRIMR7_RS24500	COG0583	DNA-binding transcription factor activity
SRIMR7_RS24510	COG2124	cytochrome p450
SRIMR7_RS24525	COG0148	phosphopyruvate hydratase activity
SRIMR7_RS24550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SRIMR7_RS24555	COG0577	efflux transmembrane transporter activity
SRIMR7_RS24560	COG1136	(ABC) transporter
SRIMR7_RS24630	COG0183	Belongs to the thiolase family
SRIMR7_RS24635	COG2755	lipolytic protein G-D-S-L family
SRIMR7_RS24650	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SRIMR7_RS24665	COG1609	Transcriptional regulator
SRIMR7_RS24680	COG0596	Alpha beta hydrolase
SRIMR7_RS24705	COG0019	diaminopimelate decarboxylase activity
SRIMR7_RS24710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIMR7_RS24710	COG2022	thiamine diphosphate biosynthetic process
SRIMR7_RS24725	COG3938	Belongs to the proline racemase family
SRIMR7_RS24735	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SRIMR7_RS24740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIMR7_RS24745	COG0402	S-adenosylhomocysteine deaminase activity
SRIMR7_RS24750	COG1228	amidohydrolase
SRIMR7_RS24760	COG2197	response regulator
SRIMR7_RS24770	COG3963	phosphatidate phosphatase activity
SRIMR7_RS24775	COG1191	sigma factor activity
SRIMR7_RS24780	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIMR7_RS24810	COG3104	oligopeptide transport
SRIMR7_RS24815	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS24820	COG5002	protein histidine kinase activity
SRIMR7_RS24855	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SRIMR7_RS24885	COG1316	TRANSCRIPTIONal
SRIMR7_RS24890	COG1607	acyl-coa hydrolase
SRIMR7_RS24910	COG0477	Major facilitator Superfamily
SRIMR7_RS24955	COG0778	Nitroreductase
SRIMR7_RS24955	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SRIMR7_RS24960	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SRIMR7_RS24995	COG1620	l-lactate permease
SRIMR7_RS25000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SRIMR7_RS25005	COG2835	tetraacyldisaccharide 4'-kinase activity
SRIMR7_RS25015	COG1482	cell wall glycoprotein biosynthetic process
SRIMR7_RS25025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SRIMR7_RS25025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SRIMR7_RS25025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SRIMR7_RS25030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SRIMR7_RS25070	COG0714	Associated with various cellular activities
SRIMR7_RS25090	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SRIMR7_RS25095	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS25100	COG5000	phosphorelay sensor kinase activity
SRIMR7_RS25100	COG5002	protein histidine kinase activity
SRIMR7_RS25105	COG0823	Involved in the tonB-independent uptake of proteins
SRIMR7_RS25120	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SRIMR7_RS25125	COG2197	response regulator
SRIMR7_RS25140	COG0653	protein targeting
SRIMR7_RS25170	COG1134	teichoic acid transport
SRIMR7_RS25180	COG1309	transcriptional regulator
SRIMR7_RS25195	COG0463	Glycosyl transferase, family 2
SRIMR7_RS25205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SRIMR7_RS25210	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS25215	COG0463	Glycosyl transferase, family 2
SRIMR7_RS25225	COG1215	transferase activity, transferring glycosyl groups
SRIMR7_RS25230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SRIMR7_RS25240	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS25245	COG1175	transmembrane transport
SRIMR7_RS25250	COG1653	transport
SRIMR7_RS25255	COG1674	ftsk spoiiie
SRIMR7_RS25260	COG0515	serine threonine protein kinase
SRIMR7_RS25265	COG0515	serine threonine protein kinase
SRIMR7_RS25270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SRIMR7_RS25285	COG2884	Cell division ATP-binding protein ftsE
SRIMR7_RS25290	COG2177	Part of the ABC transporter FtsEX involved in
SRIMR7_RS25295	COG0793	Belongs to the peptidase S41A family
SRIMR7_RS25300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SRIMR7_RS25345	COG2223	nitrite transmembrane transporter activity
SRIMR7_RS25375	COG3973	AAA domain
SRIMR7_RS25385	COG0776	regulation of translation
SRIMR7_RS25390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SRIMR7_RS25395	COG1678	Uncharacterized ACR, COG1678
SRIMR7_RS25400	COG0583	DNA-binding transcription factor activity
SRIMR7_RS25410	COG2814	Major facilitator Superfamily
SRIMR7_RS25430	COG1175	transmembrane transport
SRIMR7_RS25435	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS25440	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SRIMR7_RS25455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SRIMR7_RS25470	COG2201	protein-glutamate methylesterase activity
SRIMR7_RS25475	COG0477	Major facilitator Superfamily
SRIMR7_RS25495	COG1732	Glycine betaine
SRIMR7_RS25500	COG1174	glycine betaine transport
SRIMR7_RS25510	COG1174	glycine betaine transport
SRIMR7_RS25520	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SRIMR7_RS25525	COG0277	FAD linked oxidase domain protein
SRIMR7_RS25530	COG0222	ribosome binding
SRIMR7_RS25575	COG1335	isochorismatase
SRIMR7_RS25585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SRIMR7_RS25595	COG1113	amino acid transport
SRIMR7_RS25610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS25615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SRIMR7_RS25635	COG1234	tRNA 3'-trailer cleavage
SRIMR7_RS25640	COG1263	PTS System
SRIMR7_RS25645	COG1263	PTS System
SRIMR7_RS25650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SRIMR7_RS25655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SRIMR7_RS25670	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SRIMR7_RS25700	COG2205	protein histidine kinase activity
SRIMR7_RS25715	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SRIMR7_RS25725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRIMR7_RS25755	COG2733	membrane
SRIMR7_RS25760	COG3764	Sortase (surface protein transpeptidase)
SRIMR7_RS25770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SRIMR7_RS25780	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SRIMR7_RS25800	COG0706	membrane insertase activity
SRIMR7_RS25805	COG0179	Fumarylacetoacetate (FAA) hydrolase
SRIMR7_RS25815	COG4702	Belongs to the UPF0303 family
SRIMR7_RS25820	COG0673	inositol 2-dehydrogenase activity
SRIMR7_RS25835	COG2188	Transcriptional regulator
SRIMR7_RS25865	COG1840	ABC-type Fe3 transport system, periplasmic component
SRIMR7_RS25905	COG2186	Transcriptional regulator
SRIMR7_RS25935	COG3397	chitin binding
SRIMR7_RS25940	COG3397	chitin binding
SRIMR7_RS25955	COG1126	abc transporter atp-binding protein
SRIMR7_RS25960	COG0765	amino acid transport
SRIMR7_RS25965	COG0765	amino acid transport
SRIMR7_RS25980	COG0154	amidase activity
SRIMR7_RS26000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIMR7_RS26050	COG0588	phosphoglycerate mutase activity
SRIMR7_RS26115	COG5297	Belongs to the glycosyl hydrolase family 6
SRIMR7_RS26130	COG2910	NAD(P)H-binding
SRIMR7_RS26140	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SRIMR7_RS26145	COG4977	sequence-specific DNA binding
SRIMR7_RS26155	COG0589	response to stress
SRIMR7_RS26160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SRIMR7_RS26175	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS26190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SRIMR7_RS26195	COG1309	transcriptional regulator
SRIMR7_RS26205	COG1946	Acyl-CoA thioesterase
SRIMR7_RS26255	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SRIMR7_RS26265	COG0281	malic enzyme
SRIMR7_RS26270	COG1309	transcriptional regulator
SRIMR7_RS26275	COG1511	domain protein
SRIMR7_RS26280	COG1132	(ABC) transporter
SRIMR7_RS26315	COG1472	Belongs to the glycosyl hydrolase 3 family
SRIMR7_RS26330	COG1609	Transcriptional regulator
SRIMR7_RS26335	COG0673	inositol 2-dehydrogenase activity
SRIMR7_RS26350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SRIMR7_RS26370	COG0569	domain protein
SRIMR7_RS26370	COG0475	glutathione-regulated potassium exporter activity
SRIMR7_RS26380	COG0673	inositol 2-dehydrogenase activity
SRIMR7_RS26395	COG2814	Major facilitator Superfamily
SRIMR7_RS26400	COG1082	Xylose isomerase domain protein TIM barrel
SRIMR7_RS26405	COG0673	inositol 2-dehydrogenase activity
SRIMR7_RS26415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SRIMR7_RS26425	COG3718	enzyme involved in inositol metabolism
SRIMR7_RS26430	COG3962	Belongs to the TPP enzyme family
SRIMR7_RS26450	COG1131	(ABC) transporter
SRIMR7_RS26480	COG1077	Cell shape determining protein MreB Mrl
SRIMR7_RS26585	COG1160	GTP binding
SRIMR7_RS26590	COG0629	single-stranded DNA binding
SRIMR7_RS26615	COG2346	COG2346, Truncated hemoglobins
SRIMR7_RS26620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS26655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRIMR7_RS26670	COG1486	melibiose metabolic process
SRIMR7_RS26675	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS26680	COG1175	transmembrane transport
SRIMR7_RS26690	COG1846	Transcriptional regulator
SRIMR7_RS26690	COG1940	carbohydrate kinase activity
SRIMR7_RS26720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SRIMR7_RS26725	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SRIMR7_RS26730	COG2080	2 iron, 2 sulfur cluster binding
SRIMR7_RS26760	COG0668	transmembrane transport
SRIMR7_RS26770	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SRIMR7_RS26770	COG3291	Pkd domain containing protein
SRIMR7_RS26800	COG0583	DNA-binding transcription factor activity
SRIMR7_RS26805	COG4266	Belongs to the allantoicase family
SRIMR7_RS26825	COG2337	Toxic component of a toxin-antitoxin (TA) module
SRIMR7_RS26860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SRIMR7_RS26865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SRIMR7_RS26870	COG1113	amino acid transport
SRIMR7_RS26875	COG1113	amino acid transport
SRIMR7_RS26880	COG1268	BioY protein
SRIMR7_RS26890	COG0515	serine threonine protein kinase
SRIMR7_RS26895	COG1113	amino acid transport
SRIMR7_RS26910	COG4552	Acetyltransferase involved in intracellular survival and related
SRIMR7_RS26925	COG0475	glutathione-regulated potassium exporter activity
SRIMR7_RS26930	COG1136	(ABC) transporter
SRIMR7_RS26935	COG3594	Acyltransferase
SRIMR7_RS26960	COG0544	peptidyl-prolyl cis-trans isomerase activity
SRIMR7_RS26965	COG0740	serine-type endopeptidase activity
SRIMR7_RS26970	COG0740	serine-type endopeptidase activity
SRIMR7_RS26975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SRIMR7_RS26990	COG0525	valine-tRNA ligase activity
SRIMR7_RS27000	COG0768	penicillin binding
SRIMR7_RS27005	COG0285	dihydrofolate synthase activity
SRIMR7_RS27015	COG0105	UTP biosynthetic process
SRIMR7_RS27020	COG1077	Cell shape determining protein MreB Mrl
SRIMR7_RS27040	COG0772	Belongs to the SEDS family
SRIMR7_RS27050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SRIMR7_RS27055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIMR7_RS27055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIMR7_RS27080	COG1530	ribonuclease E activity
SRIMR7_RS27085	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SRIMR7_RS27090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SRIMR7_RS27095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SRIMR7_RS27100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SRIMR7_RS27110	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SRIMR7_RS27125	COG0501	Belongs to the peptidase M48B family
SRIMR7_RS27140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SRIMR7_RS27150	COG0799	negative regulation of ribosome biogenesis
SRIMR7_RS27155	COG0588	phosphoglycerate mutase activity
SRIMR7_RS27205	COG0495	leucyl-tRNA aminoacylation
SRIMR7_RS27215	COG1307	EDD domain protein, DegV family
SRIMR7_RS27220	COG1555	photosystem II stabilization
SRIMR7_RS27220	COG1596	polysaccharide export
SRIMR7_RS27225	COG1234	tRNA 3'-trailer cleavage
SRIMR7_RS27230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SRIMR7_RS27235	COG1959	2 iron, 2 sulfur cluster binding
SRIMR7_RS27260	COG0268	Binds directly to 16S ribosomal RNA
SRIMR7_RS27265	COG0481	GTPase activity
SRIMR7_RS27275	COG1022	Amp-dependent synthetase and ligase
SRIMR7_RS27280	COG3437	response regulator, receiver
SRIMR7_RS27320	COG1420	regulation of RNA biosynthetic process
SRIMR7_RS27325	COG0484	heat shock protein binding
SRIMR7_RS27350	COG0537	adenosine 5'-monophosphoramidase activity
SRIMR7_RS27355	COG1234	tRNA 3'-trailer cleavage
SRIMR7_RS27365	COG4948	Mandelate Racemase Muconate Lactonizing
SRIMR7_RS27380	COG1486	melibiose metabolic process
SRIMR7_RS27385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SRIMR7_RS27395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SRIMR7_RS27405	COG2814	Major facilitator Superfamily
SRIMR7_RS27440	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS27445	COG0492	ferredoxin-NADP+ reductase activity
SRIMR7_RS27460	COG0475	glutathione-regulated potassium exporter activity
SRIMR7_RS27465	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SRIMR7_RS27475	COG2723	6-phospho-beta-galactosidase activity
SRIMR7_RS27490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SRIMR7_RS27500	COG1381	Involved in DNA repair and RecF pathway recombination
SRIMR7_RS27505	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SRIMR7_RS27515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SRIMR7_RS27520	COG1121	(ABC) transporter
SRIMR7_RS27530	COG0423	glycine-tRNA ligase activity
SRIMR7_RS27545	COG2197	response regulator
SRIMR7_RS27560	COG0667	Aldo Keto reductase
SRIMR7_RS27565	COG0477	Major facilitator Superfamily
SRIMR7_RS27590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SRIMR7_RS27590	COG0574	Belongs to the PEP-utilizing enzyme family
SRIMR7_RS27600	COG2175	clavaminate synthase activity
SRIMR7_RS27610	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS27615	COG1175	transmembrane transport
SRIMR7_RS27625	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS27630	COG0789	Transcriptional regulator
SRIMR7_RS27640	COG2814	Major facilitator Superfamily
SRIMR7_RS27670	COG3485	protocatechuate 3,4-dioxygenase
SRIMR7_RS27680	COG0531	amino acid
SRIMR7_RS27700	COG2146	nitrite reductase [NAD(P)H] activity
SRIMR7_RS27700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIMR7_RS27705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIMR7_RS27715	COG2197	response regulator
SRIMR7_RS27730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIMR7_RS27765	COG2382	esterase
SRIMR7_RS27805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SRIMR7_RS27820	COG0243	molybdopterin cofactor binding
SRIMR7_RS27830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SRIMR7_RS27845	COG0358	DNA primase activity
SRIMR7_RS27850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SRIMR7_RS27855	COG1070	Carbohydrate kinase
SRIMR7_RS27885	COG1834	amidinotransferase
SRIMR7_RS27900	COG3835	regulator
SRIMR7_RS27910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SRIMR7_RS27910	COG2080	2 iron, 2 sulfur cluster binding
SRIMR7_RS27915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SRIMR7_RS27925	COG1077	Cell shape determining protein MreB Mrl
SRIMR7_RS27935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SRIMR7_RS27965	COG4981	capsule polysaccharide biosynthetic process
SRIMR7_RS27970	COG0500	methyltransferase
SRIMR7_RS28000	COG0477	Major facilitator Superfamily
SRIMR7_RS28010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SRIMR7_RS28020	COG2130	NADP-dependent
SRIMR7_RS28025	COG1764	response to oxidative stress
SRIMR7_RS28030	COG1609	Transcriptional regulator
SRIMR7_RS28040	COG1172	Belongs to the binding-protein-dependent transport system permease family
SRIMR7_RS28050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SRIMR7_RS28100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIMR7_RS28105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIMR7_RS28110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIMR7_RS28135	COG0789	Transcriptional regulator
SRIMR7_RS28140	COG0667	Aldo Keto reductase
SRIMR7_RS28155	COG2197	response regulator
SRIMR7_RS28160	COG4585	Histidine kinase
SRIMR7_RS28175	COG1309	transcriptional regulator
SRIMR7_RS28180	COG0477	Major facilitator Superfamily
SRIMR7_RS28195	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SRIMR7_RS28250	COG0586	Pfam SNARE associated Golgi protein
SRIMR7_RS28255	COG4585	Histidine kinase
SRIMR7_RS28280	COG4948	Mandelate Racemase Muconate Lactonizing
SRIMR7_RS28305	COG2259	Doxx family
SRIMR7_RS28315	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SRIMR7_RS28330	COG1120	ATPase activity
SRIMR7_RS28395	COG1072	(Pantothenic acid kinase))
SRIMR7_RS28425	COG2259	Doxx family
SRIMR7_RS28450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SRIMR7_RS28455	COG3409	Peptidoglycan-binding domain 1 protein
SRIMR7_RS28455	COG0860	N-Acetylmuramoyl-L-alanine amidase
SRIMR7_RS28465	COG0456	acetyltransferase
SRIMR7_RS28500	COG0477	Major facilitator Superfamily
SRIMR7_RS28510	COG0667	Aldo Keto reductase
SRIMR7_RS28525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SRIMR7_RS28550	COG2124	cytochrome p450
SRIMR7_RS28555	COG0183	Belongs to the thiolase family
SRIMR7_RS28565	COG2318	DinB family
SRIMR7_RS28590	COG3845	ABC transporter
SRIMR7_RS28605	COG1657	PFAM Prenyltransferase squalene oxidase
SRIMR7_RS28625	COG0515	serine threonine protein kinase
SRIMR7_RS28635	COG1132	(ABC) transporter
SRIMR7_RS28640	COG1132	(ABC) transporter
SRIMR7_RS28650	COG1309	transcriptional regulator
SRIMR7_RS28655	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS28685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIMR7_RS28695	COG0860	N-Acetylmuramoyl-L-alanine amidase
SRIMR7_RS28705	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS28710	COG0183	Belongs to the thiolase family
SRIMR7_RS28720	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS28725	COG0509	glycine decarboxylation via glycine cleavage system
SRIMR7_RS28730	COG2197	response regulator
SRIMR7_RS28770	COG4585	Histidine kinase
SRIMR7_RS28775	COG2030	dehydratase
SRIMR7_RS28785	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS28805	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SRIMR7_RS28820	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SRIMR7_RS28825	COG0800	Aldolase
SRIMR7_RS28830	COG3022	response to hydroperoxide
SRIMR7_RS28835	COG0557	exoribonuclease II activity
SRIMR7_RS28845	COG0789	Transcriptional regulator
SRIMR7_RS28855	COG1957	nucleoside hydrolase
SRIMR7_RS28860	COG3903	Transcriptional regulator
SRIMR7_RS28860	COG3629	intracellular signal transduction
SRIMR7_RS29215	COG0776	regulation of translation
SRIMR7_RS29355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS29360	COG0535	radical SAM domain protein
SRIMR7_RS29390	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SRIMR7_RS29415	COG3540	Alkaline phosphatase
SRIMR7_RS29420	COG2814	Major facilitator Superfamily
SRIMR7_RS29425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRIMR7_RS29435	COG1834	amidinotransferase
SRIMR7_RS29460	COG0672	)-iron permease
SRIMR7_RS29465	COG2837	iron assimilation
SRIMR7_RS29475	COG1120	ATPase activity
SRIMR7_RS29480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS29485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SRIMR7_RS29505	COG5398	heme oxygenase
SRIMR7_RS29535	COG1175	transmembrane transport
SRIMR7_RS29540	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS29565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS29570	COG1994	Peptidase M50
SRIMR7_RS29600	COG1687	branched-chain amino acid
SRIMR7_RS29605	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SRIMR7_RS29610	COG0477	Major facilitator Superfamily
SRIMR7_RS29625	COG2814	Major facilitator Superfamily
SRIMR7_RS29635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SRIMR7_RS29635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SRIMR7_RS29640	COG2132	Multicopper oxidase
SRIMR7_RS29665	COG0174	glutamine synthetase
SRIMR7_RS29670	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SRIMR7_RS29680	COG1609	Transcriptional regulator
SRIMR7_RS29685	COG0366	Alpha amylase catalytic
SRIMR7_RS29690	COG2182	Extracellular solute-binding protein
SRIMR7_RS29695	COG1175	transmembrane transport
SRIMR7_RS29700	COG3833	ABC-type maltose transport systems, permease component
SRIMR7_RS29705	COG0366	Alpha amylase catalytic
SRIMR7_RS29730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIMR7_RS29790	COG1309	transcriptional regulator
SRIMR7_RS29815	COG2197	response regulator
SRIMR7_RS29820	COG4585	Histidine kinase
SRIMR7_RS29835	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS29850	COG3591	Belongs to the peptidase S1B family
SRIMR7_RS29855	COG0673	inositol 2-dehydrogenase activity
SRIMR7_RS29870	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS29875	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS29880	COG2205	protein histidine kinase activity
SRIMR7_RS29925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SRIMR7_RS29930	COG0321	lipoyl(octanoyl) transferase activity
SRIMR7_RS29945	COG1090	epimerase
SRIMR7_RS29970	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SRIMR7_RS29980	COG0508	dehydrogenase complex catalyzes the overall conversion of
SRIMR7_RS29985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SRIMR7_RS29990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SRIMR7_RS30000	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS30025	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SRIMR7_RS30040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SRIMR7_RS30040	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SRIMR7_RS30045	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SRIMR7_RS30065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRIMR7_RS30070	COG1132	(ABC) transporter
SRIMR7_RS30075	COG2226	methyltransferase
SRIMR7_RS30095	COG4585	Histidine kinase
SRIMR7_RS30100	COG2197	response regulator
SRIMR7_RS30105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SRIMR7_RS30115	COG2161	toxin-antitoxin pair type II binding
SRIMR7_RS30120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SRIMR7_RS30140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SRIMR7_RS30150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SRIMR7_RS30155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SRIMR7_RS30165	COG1376	ErfK ybiS ycfS ynhG family protein
SRIMR7_RS30175	COG1845	cytochrome c oxidase, subunit III
SRIMR7_RS30180	COG2010	Cytochrome c
SRIMR7_RS30185	COG0723	plastoquinol--plastocyanin reductase activity
SRIMR7_RS30190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SRIMR7_RS30195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SRIMR7_RS30200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SRIMR7_RS30210	COG0705	Rhomboid family
SRIMR7_RS30230	COG3883	PFAM NLP P60 protein
SRIMR7_RS30230	COG0791	NLP P60 protein
SRIMR7_RS30245	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS30265	COG0003	Pfam Anion-transporting ATPase
SRIMR7_RS30275	COG1940	carbohydrate kinase activity
SRIMR7_RS30310	COG2197	response regulator
SRIMR7_RS30315	COG0205	6-phosphofructokinase activity
SRIMR7_RS30320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SRIMR7_RS30330	COG2267	carboxylic ester hydrolase activity
SRIMR7_RS30335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIMR7_RS30340	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SRIMR7_RS30350	COG2193	ferroxidase activity
SRIMR7_RS30355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SRIMR7_RS30365	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SRIMR7_RS30370	COG0515	serine threonine protein kinase
SRIMR7_RS30370	COG2815	serine threonine protein kinase
SRIMR7_RS30375	COG2022	thiamine diphosphate biosynthetic process
SRIMR7_RS30385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIMR7_RS30385	COG2022	thiamine diphosphate biosynthetic process
SRIMR7_RS30400	COG0352	thiamine-phosphate diphosphorylase activity
SRIMR7_RS30415	COG1233	COG1233 Phytoene dehydrogenase and related
SRIMR7_RS30425	COG1309	transcriptional regulator
SRIMR7_RS30445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIMR7_RS30465	COG0714	Associated with various cellular activities
SRIMR7_RS30475	COG0275	rRNA processing
SRIMR7_RS30485	COG0768	penicillin binding
SRIMR7_RS30490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SRIMR7_RS30500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SRIMR7_RS30505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SRIMR7_RS30515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SRIMR7_RS30520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SRIMR7_RS30540	COG1799	cell septum assembly
SRIMR7_RS30550	COG3599	regulation of cell shape
SRIMR7_RS30555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SRIMR7_RS30565	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SRIMR7_RS30620	COG0587	DNA-directed DNA polymerase activity
SRIMR7_RS30630	COG1432	Conserved Protein
SRIMR7_RS30650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SRIMR7_RS30665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SRIMR7_RS30670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SRIMR7_RS30675	COG0131	Imidazoleglycerol-phosphate dehydratase
SRIMR7_RS30685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SRIMR7_RS30690	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SRIMR7_RS30695	COG0251	oxidation-reduction process
SRIMR7_RS30700	COG0107	imidazoleglycerol-phosphate synthase activity
SRIMR7_RS30715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SRIMR7_RS30720	COG1053	succinate dehydrogenase
SRIMR7_RS30730	COG0583	DNA-binding transcription factor activity
SRIMR7_RS30735	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SRIMR7_RS30745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SRIMR7_RS30765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SRIMR7_RS30790	COG0134	indole-3-glycerol-phosphate synthase activity
SRIMR7_RS30800	COG0133	tryptophan synthase activity
SRIMR7_RS30805	COG0159	tryptophan synthase activity
SRIMR7_RS30815	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SRIMR7_RS30820	COG2301	Belongs to the HpcH HpaI aldolase family
SRIMR7_RS30825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIMR7_RS30850	COG1609	Transcriptional regulator
SRIMR7_RS30860	COG0069	glutamate synthase activity
SRIMR7_RS30860	COG0067	glutamate synthase
SRIMR7_RS30860	COG0070	glutamate synthase
SRIMR7_RS30870	COG1846	Transcriptional regulator
SRIMR7_RS30875	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS30880	COG3467	pyridoxamine 5'-phosphate
SRIMR7_RS30895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SRIMR7_RS30900	COG0596	Alpha beta hydrolase
SRIMR7_RS30935	COG0464	growth
SRIMR7_RS30955	COG2197	response regulator
SRIMR7_RS30965	COG0366	Alpha amylase catalytic
SRIMR7_RS30965	COG1470	cell adhesion involved in biofilm formation
SRIMR7_RS30995	COG0737	Belongs to the 5'-nucleotidase family
SRIMR7_RS31055	COG2050	protein possibly involved in aromatic compounds catabolism
SRIMR7_RS31090	COG1643	Atp-dependent helicase
SRIMR7_RS31095	COG2226	methyltransferase
SRIMR7_RS31120	COG0237	dephospho-CoA kinase activity
SRIMR7_RS31145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SRIMR7_RS31150	COG4279	zinc finger
SRIMR7_RS31195	COG0584	glycerophosphoryl diester phosphodiesterase
SRIMR7_RS31200	COG0556	nucleotide-excision repair
SRIMR7_RS31245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SRIMR7_RS31260	COG1063	alcohol dehydrogenase
SRIMR7_RS31265	COG2814	Major facilitator Superfamily
SRIMR7_RS31305	COG0322	excinuclease ABC activity
SRIMR7_RS31310	COG1660	Displays ATPase and GTPase activities
SRIMR7_RS31320	COG1481	regulation of sporulation
SRIMR7_RS31325	COG0456	acetyltransferase
SRIMR7_RS31325	COG0454	-acetyltransferase
SRIMR7_RS31335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SRIMR7_RS31340	COG0126	phosphoglycerate kinase activity
SRIMR7_RS31345	COG0149	triose-phosphate isomerase activity
SRIMR7_RS31350	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SRIMR7_RS31360	COG0166	Belongs to the GPI family
SRIMR7_RS31370	COG0363	glucosamine-6-phosphate deaminase activity
SRIMR7_RS31385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SRIMR7_RS31390	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SRIMR7_RS31395	COG0109	protoheme IX farnesyltransferase activity
SRIMR7_RS31410	COG1612	heme a metabolic process
SRIMR7_RS31435	COG0719	Fe-S assembly protein
SRIMR7_RS31445	COG0396	ATPase activity
SRIMR7_RS31450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SRIMR7_RS31455	COG0822	iron-sulfur transferase activity
SRIMR7_RS31480	COG2076	Multidrug Resistance protein
SRIMR7_RS31485	COG3226	Transcriptional regulator
SRIMR7_RS31495	COG2171	N-acyltransferase activity
SRIMR7_RS31515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRIMR7_RS31545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIMR7_RS31580	COG2261	transglycosylase associated protein
SRIMR7_RS31585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SRIMR7_RS31590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRIMR7_RS31620	COG4585	Histidine kinase
SRIMR7_RS31625	COG1414	Transcriptional regulator
SRIMR7_RS31635	COG0456	acetyltransferase
SRIMR7_RS31670	COG5285	phytanoyl-CoA dioxygenase
SRIMR7_RS31675	COG1917	Cupin 2, conserved barrel domain protein
SRIMR7_RS31680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SRIMR7_RS31695	COG0385	Bile acid
SRIMR7_RS31720	COG1797	cobyrinic acid a,c-diamide synthase activity
SRIMR7_RS31725	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SRIMR7_RS31735	COG1492	cobalamin metabolic process
SRIMR7_RS31740	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SRIMR7_RS31760	COG0235	Class ii aldolase
SRIMR7_RS31785	COG0488	(ABC) transporter
SRIMR7_RS31795	COG1024	Enoyl-CoA hydratase
SRIMR7_RS31805	COG1302	Protein conserved in bacteria
SRIMR7_RS31835	COG3387	PFAM Glycoside hydrolase 15-related
SRIMR7_RS31850	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SRIMR7_RS31890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SRIMR7_RS31895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SRIMR7_RS31910	COG2261	transglycosylase associated protein
SRIMR7_RS31915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SRIMR7_RS31930	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS31935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SRIMR7_RS31940	COG2186	Transcriptional regulator
SRIMR7_RS31945	COG2807	transmembrane transport
SRIMR7_RS31960	COG3830	Belongs to the UPF0237 family
SRIMR7_RS31960	COG0560	Phosphoserine phosphatase
SRIMR7_RS31970	COG0842	Transport permease protein
SRIMR7_RS31970	COG1716	ATPase activity
SRIMR7_RS31970	COG1131	(ABC) transporter
SRIMR7_RS31985	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SRIMR7_RS31990	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS31995	COG4585	Histidine kinase
SRIMR7_RS32000	COG2197	response regulator
SRIMR7_RS32020	COG1119	ATPase activity
SRIMR7_RS32045	COG1881	PFAM PEBP family protein
SRIMR7_RS32055	COG2094	Belongs to the DNA glycosylase MPG family
SRIMR7_RS32095	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SRIMR7_RS32110	COG0647	UMP catabolic process
SRIMR7_RS32125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS32130	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS32135	COG1120	ATPase activity
SRIMR7_RS32155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SRIMR7_RS32175	COG0497	DNA recombination
SRIMR7_RS32185	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS32215	COG3387	PFAM Glycoside hydrolase 15-related
SRIMR7_RS32220	COG0504	CTP synthase activity
SRIMR7_RS32225	COG0494	nUDIX hydrolase
SRIMR7_RS32235	COG0686	Belongs to the AlaDH PNT family
SRIMR7_RS32250	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SRIMR7_RS32255	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SRIMR7_RS32260	COG1187	pseudouridine synthase activity
SRIMR7_RS32270	COG3541	Predicted nucleotidyltransferase
SRIMR7_RS32295	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SRIMR7_RS32305	COG1160	GTP binding
SRIMR7_RS32335	COG0411	ABC transporter
SRIMR7_RS32370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SRIMR7_RS32430	COG0671	phosphoesterase, PA-phosphatase related
SRIMR7_RS32440	COG0477	Major facilitator Superfamily
SRIMR7_RS32445	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS32450	COG1799	cell septum assembly
SRIMR7_RS32460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIMR7_RS32465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIMR7_RS32505	COG0326	Molecular chaperone. Has ATPase activity
SRIMR7_RS32515	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS32525	COG0587	DNA-directed DNA polymerase activity
SRIMR7_RS32530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SRIMR7_RS32560	COG0019	diaminopimelate decarboxylase activity
SRIMR7_RS32590	COG1725	Transcriptional regulator
SRIMR7_RS32600	COG1834	amidinotransferase
SRIMR7_RS32620	COG0726	polysaccharide deacetylase
SRIMR7_RS32625	COG1215	transferase activity, transferring glycosyl groups
SRIMR7_RS32630	COG0463	Glycosyl transferase, family 2
SRIMR7_RS32650	COG0515	serine threonine protein kinase
SRIMR7_RS32670	COG1595	DNA-templated transcription, initiation
SRIMR7_RS32685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIMR7_RS32695	COG2814	Major facilitator Superfamily
SRIMR7_RS32695	COG0477	Major facilitator Superfamily
SRIMR7_RS32700	COG4195	phage-related replication protein
SRIMR7_RS32705	COG2188	Transcriptional regulator
SRIMR7_RS32710	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SRIMR7_RS32715	COG2851	Citrate transporter
SRIMR7_RS32775	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS32815	COG0477	Major facilitator Superfamily
SRIMR7_RS32820	COG3876	Protein conserved in bacteria
SRIMR7_RS32830	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS32840	COG0456	acetyltransferase
SRIMR7_RS32840	COG1846	Transcriptional regulator
SRIMR7_RS32845	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS32860	COG2149	membrane
SRIMR7_RS32865	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SRIMR7_RS32890	COG3573	Dehydrogenase
SRIMR7_RS32925	COG3173	Aminoglycoside phosphotransferase
SRIMR7_RS32930	COG5002	protein histidine kinase activity
SRIMR7_RS32935	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS32960	COG2124	cytochrome p450
SRIMR7_RS32965	COG0488	(ABC) transporter
SRIMR7_RS33060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIMR7_RS33090	COG0667	Aldo Keto reductase
SRIMR7_RS33095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIMR7_RS33105	COG0598	Magnesium transport protein CorA
SRIMR7_RS33125	COG0215	cysteine-tRNA ligase activity
SRIMR7_RS33150	COG4948	Mandelate Racemase Muconate Lactonizing
SRIMR7_RS33155	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS33165	COG1129	ABC transporter
SRIMR7_RS33170	COG4211	Belongs to the binding-protein-dependent transport system permease family
SRIMR7_RS33190	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS33195	COG2186	Transcriptional regulator
SRIMR7_RS33200	COG0402	S-adenosylhomocysteine deaminase activity
SRIMR7_RS33205	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SRIMR7_RS33210	COG0235	Class ii aldolase
SRIMR7_RS33220	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SRIMR7_RS33225	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SRIMR7_RS33230	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SRIMR7_RS33235	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SRIMR7_RS33240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SRIMR7_RS33245	COG1414	Transcriptional regulator
SRIMR7_RS33250	COG0646	methionine synthase
SRIMR7_RS33250	COG1410	methionine synthase
SRIMR7_RS33260	COG4166	transmembrane transport
SRIMR7_RS33270	COG2197	response regulator
SRIMR7_RS33280	COG0517	IMP dehydrogenase activity
SRIMR7_RS33280	COG1994	Peptidase M50
SRIMR7_RS33300	COG1222	aaa ATPase
SRIMR7_RS33305	COG4122	O-methyltransferase activity
SRIMR7_RS33315	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SRIMR7_RS33320	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SRIMR7_RS33325	COG1609	Transcriptional regulator
SRIMR7_RS33335	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SRIMR7_RS33350	COG2378	regulation of single-species biofilm formation
SRIMR7_RS33370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SRIMR7_RS33375	COG0805	protein transport
SRIMR7_RS33385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIMR7_RS33400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SRIMR7_RS33405	COG4175	Glycine betaine
SRIMR7_RS33405	COG0517	IMP dehydrogenase activity
SRIMR7_RS33410	COG4176	ABC-type proline glycine betaine transport system permease component
SRIMR7_RS33430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SRIMR7_RS33435	COG0531	amino acid
SRIMR7_RS33440	COG2186	Transcriptional regulator
SRIMR7_RS33445	COG0174	glutamine synthetase
SRIMR7_RS33485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SRIMR7_RS33495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SRIMR7_RS33500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SRIMR7_RS33505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SRIMR7_RS33510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SRIMR7_RS33515	COG5002	protein histidine kinase activity
SRIMR7_RS33520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SRIMR7_RS33525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SRIMR7_RS33525	COG0072	phenylalanine-tRNA ligase activity
SRIMR7_RS33555	COG1649	PFAM Uncharacterised BCR, COG1649
SRIMR7_RS33565	COG0697	spore germination
SRIMR7_RS33580	COG1486	melibiose metabolic process
SRIMR7_RS33585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SRIMR7_RS33590	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS33595	COG1175	transmembrane transport
SRIMR7_RS33600	COG2182	Extracellular solute-binding protein
SRIMR7_RS33635	COG1595	DNA-templated transcription, initiation
SRIMR7_RS33640	COG1660	Displays ATPase and GTPase activities
SRIMR7_RS33665	COG2838	Isocitrate dehydrogenase
SRIMR7_RS33680	COG4585	Histidine kinase
SRIMR7_RS33685	COG2197	response regulator
SRIMR7_RS33715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SRIMR7_RS33730	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SRIMR7_RS33735	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SRIMR7_RS33740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SRIMR7_RS33745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRIMR7_RS33750	COG1438	arginine binding
SRIMR7_RS33755	COG1228	amidohydrolase
SRIMR7_RS33810	COG0137	argininosuccinate synthase activity
SRIMR7_RS33815	COG0165	Argininosuccinate lyase
SRIMR7_RS33825	COG0477	Major facilitator Superfamily
SRIMR7_RS33830	COG0737	Belongs to the 5'-nucleotidase family
SRIMR7_RS33840	COG0584	glycerophosphoryl diester phosphodiesterase
SRIMR7_RS33865	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SRIMR7_RS33870	COG2011	ABC-type metal ion transport system permease component
SRIMR7_RS33875	COG1464	Belongs to the NlpA lipoprotein family
SRIMR7_RS33890	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SRIMR7_RS33895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SRIMR7_RS33895	COG1648	precorrin-2 dehydrogenase activity
SRIMR7_RS33900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SRIMR7_RS33960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SRIMR7_RS34020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SRIMR7_RS34035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SRIMR7_RS34065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SRIMR7_RS34070	COG1560	Kdo2-lipid A biosynthetic process
SRIMR7_RS34075	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS34090	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SRIMR7_RS34095	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SRIMR7_RS34100	COG0217	transcriptional regulatory protein
SRIMR7_RS34105	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SRIMR7_RS34110	COG0632	four-way junction helicase activity
SRIMR7_RS34115	COG2255	four-way junction helicase activity
SRIMR7_RS34125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SRIMR7_RS34130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SRIMR7_RS34135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SRIMR7_RS34140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SRIMR7_RS34145	COG1196	nuclear chromosome segregation
SRIMR7_RS34150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SRIMR7_RS34160	COG0124	histidyl-tRNA synthetase
SRIMR7_RS34180	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SRIMR7_RS34200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SRIMR7_RS34205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SRIMR7_RS34215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SRIMR7_RS34220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SRIMR7_RS34225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SRIMR7_RS34230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SRIMR7_RS34235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SRIMR7_RS34245	COG0006	proline dipeptidase activity
SRIMR7_RS34250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SRIMR7_RS34255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SRIMR7_RS34265	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SRIMR7_RS34270	COG0540	Belongs to the ATCase OTCase family
SRIMR7_RS34275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SRIMR7_RS34285	COG0505	Belongs to the CarA family
SRIMR7_RS34290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SRIMR7_RS34295	COG0167	dihydroorotate dehydrogenase activity
SRIMR7_RS34300	COG0284	orotidine-5'-phosphate decarboxylase activity
SRIMR7_RS34325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SRIMR7_RS34360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SRIMR7_RS34370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SRIMR7_RS34375	COG2390	Transcriptional regulator
SRIMR7_RS34415	COG0531	amino acid
SRIMR7_RS34435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SRIMR7_RS34455	COG2233	PERMEase
SRIMR7_RS34465	COG0738	Major facilitator superfamily
SRIMR7_RS34470	COG1846	Transcriptional regulator
SRIMR7_RS34470	COG1940	carbohydrate kinase activity
SRIMR7_RS34475	COG0702	epimerase
SRIMR7_RS34490	COG3201	nicotinamide mononucleotide transporter
SRIMR7_RS34495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SRIMR7_RS34495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SRIMR7_RS34500	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SRIMR7_RS34505	COG0140	phosphoribosyl-ATP diphosphatase activity
SRIMR7_RS34510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SRIMR7_RS34565	COG0671	phosphoesterase, PA-phosphatase related
SRIMR7_RS34590	COG0584	glycerophosphoryl diester phosphodiesterase
SRIMR7_RS34635	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SRIMR7_RS34645	COG1191	sigma factor activity
SRIMR7_RS34670	COG2318	DinB family
SRIMR7_RS34675	COG4249	Peptidase C14 caspase catalytic subunit p20
SRIMR7_RS34675	COG2319	Wd-40 repeat
SRIMR7_RS34690	COG3973	AAA domain
SRIMR7_RS34725	COG3345	alpha-galactosidase
SRIMR7_RS34735	COG1175	transmembrane transport
SRIMR7_RS34740	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS34760	COG0644	oxidoreductase
SRIMR7_RS34765	COG4585	Histidine kinase
SRIMR7_RS34770	COG2197	response regulator
SRIMR7_RS34790	COG1940	carbohydrate kinase activity
SRIMR7_RS34840	COG1349	DNA-binding transcription factor activity
SRIMR7_RS34850	COG0464	growth
SRIMR7_RS34890	COG0463	Glycosyl transferase, family 2
SRIMR7_RS34895	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SRIMR7_RS34955	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS35000	COG0640	Transcriptional regulator
SRIMR7_RS35020	COG2111	Na H antiporter
SRIMR7_RS35025	COG1006	Multisubunit Na H antiporter MnhC subunit
SRIMR7_RS35030	COG1007	ATP synthesis coupled electron transport
SRIMR7_RS35040	COG1461	Dihydroxyacetone kinase
SRIMR7_RS35045	COG2376	Dihydroxyacetone kinase
SRIMR7_RS35080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SRIMR7_RS35095	COG0596	Alpha beta hydrolase
SRIMR7_RS35100	COG0604	alcohol dehydrogenase
SRIMR7_RS35100	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS35100	COG3321	synthase
SRIMR7_RS35120	COG1309	transcriptional regulator
SRIMR7_RS35130	COG1414	Transcriptional regulator
SRIMR7_RS35135	COG3386	PFAM SMP-30 Gluconolaconase
SRIMR7_RS35150	COG4214	carbohydrate transport
SRIMR7_RS35190	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIMR7_RS35190	COG2172	sigma factor antagonist activity
SRIMR7_RS35190	COG2208	phosphoserine phosphatase activity
SRIMR7_RS35205	COG2318	DinB family
SRIMR7_RS35215	COG0367	asparagine synthase
SRIMR7_RS35240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SRIMR7_RS35245	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS35250	COG0515	serine threonine protein kinase
SRIMR7_RS35265	COG2070	2-Nitropropane dioxygenase
SRIMR7_RS35275	COG2366	antibiotic biosynthetic process
SRIMR7_RS35280	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS35325	COG1605	Chorismate mutase
SRIMR7_RS35380	COG4221	oxidoreductase activity
SRIMR7_RS35415	COG2124	cytochrome p450
SRIMR7_RS35420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRIMR7_RS35465	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS35470	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS35485	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SRIMR7_RS35495	COG1984	allophanate hydrolase subunit 2
SRIMR7_RS35500	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SRIMR7_RS35505	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SRIMR7_RS35525	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SRIMR7_RS35570	COG2146	nitrite reductase [NAD(P)H] activity
SRIMR7_RS35625	COG0442	prolyl-tRNA aminoacylation
SRIMR7_RS35630	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SRIMR7_RS35635	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SRIMR7_RS35640	COG3447	MASE1 domain protein
SRIMR7_RS35640	COG5001	Diguanylate cyclase
SRIMR7_RS35640	COG5002	protein histidine kinase activity
SRIMR7_RS35645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIMR7_RS35655	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SRIMR7_RS35670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SRIMR7_RS35680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SRIMR7_RS35710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SRIMR7_RS35730	COG1716	ATPase activity
SRIMR7_RS35750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SRIMR7_RS35760	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SRIMR7_RS35760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SRIMR7_RS35785	COG0384	phenazine biosynthesis protein PhzF
SRIMR7_RS35795	COG0789	Transcriptional regulator
SRIMR7_RS35805	COG1695	Transcriptional regulator
SRIMR7_RS35820	COG0697	spore germination
SRIMR7_RS35840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SRIMR7_RS35845	COG0697	spore germination
SRIMR7_RS35860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SRIMR7_RS35860	COG0825	malonyl-CoA metabolic process
SRIMR7_RS35865	COG0318	PFAM AMP-dependent synthetase and ligase
SRIMR7_RS35885	COG4946	Tricorn protease homolog
SRIMR7_RS35885	COG1506	peptidase
SRIMR7_RS35885	COG0823	Involved in the tonB-independent uptake of proteins
SRIMR7_RS35940	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS35960	COG0154	amidase activity
SRIMR7_RS35985	COG0667	Aldo Keto reductase
SRIMR7_RS35990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SRIMR7_RS36025	COG1132	(ABC) transporter
SRIMR7_RS36035	COG0640	Transcriptional regulator
SRIMR7_RS36040	COG1252	NADH dehydrogenase
SRIMR7_RS36050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SRIMR7_RS36065	COG0386	Belongs to the glutathione peroxidase family
SRIMR7_RS36070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SRIMR7_RS36075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRIMR7_RS36130	COG2267	carboxylic ester hydrolase activity
SRIMR7_RS36135	COG0531	amino acid
SRIMR7_RS36185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIMR7_RS36190	COG0019	diaminopimelate decarboxylase activity
SRIMR7_RS36195	COG0531	amino acid
SRIMR7_RS36210	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SRIMR7_RS36215	COG2205	protein histidine kinase activity
SRIMR7_RS36255	COG4733	cellulase activity
SRIMR7_RS36260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SRIMR7_RS36320	COG0583	DNA-binding transcription factor activity
SRIMR7_RS36350	COG3795	YCII-related domain
SRIMR7_RS36355	COG4941	Belongs to the sigma-70 factor family
SRIMR7_RS36370	COG1595	DNA-templated transcription, initiation
SRIMR7_RS36420	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS36425	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS36430	COG2205	protein histidine kinase activity
SRIMR7_RS36450	COG1968	undecaprenyl-diphosphatase activity
SRIMR7_RS36465	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SRIMR7_RS36510	COG3285	dna ligase
SRIMR7_RS36510	COG1793	dna ligase
SRIMR7_RS36520	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIMR7_RS36525	COG0248	Ppx GppA phosphatase
SRIMR7_RS36545	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS36550	COG0300	oxidoreductase activity
SRIMR7_RS36580	COG0110	maltose O-acetyltransferase activity
SRIMR7_RS36590	COG1470	cell adhesion involved in biofilm formation
SRIMR7_RS36595	COG2124	cytochrome p450
SRIMR7_RS36600	COG1309	transcriptional regulator
SRIMR7_RS36635	COG1832	CoA-binding protein
SRIMR7_RS36640	COG1739	Uncharacterized protein family UPF0029
SRIMR7_RS36670	COG1335	isochorismatase
SRIMR7_RS36675	COG1982	Orn Lys Arg decarboxylase major
SRIMR7_RS36680	COG0243	molybdopterin cofactor binding
SRIMR7_RS36680	COG3383	formate dehydrogenase (NAD+) activity
SRIMR7_RS36685	COG0437	4 iron, 4 sulfur cluster binding
SRIMR7_RS36700	COG1846	Transcriptional regulator
SRIMR7_RS36710	COG1597	lipid kinase activity
SRIMR7_RS36720	COG2706	6-phosphogluconolactonase activity
SRIMR7_RS36730	COG0823	Involved in the tonB-independent uptake of proteins
SRIMR7_RS36735	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SRIMR7_RS36740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SRIMR7_RS36785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS36795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS36820	COG0535	radical SAM domain protein
SRIMR7_RS36830	COG1140	nitrate reductase beta subunit
SRIMR7_RS36835	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SRIMR7_RS36840	COG2181	nitrate reductase activity
SRIMR7_RS36850	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SRIMR7_RS36860	COG1140	nitrate reductase beta subunit
SRIMR7_RS36900	COG1882	Formate acetyltransferase
SRIMR7_RS36905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SRIMR7_RS36920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SRIMR7_RS36920	COG2146	nitrite reductase [NAD(P)H] activity
SRIMR7_RS36945	COG0667	Aldo Keto reductase
SRIMR7_RS37030	COG1113	amino acid transport
SRIMR7_RS37040	COG1132	(ABC) transporter
SRIMR7_RS37055	COG0420	3'-5' exonuclease activity
SRIMR7_RS37060	COG0419	ATPase involved in DNA repair
SRIMR7_RS37065	COG1522	sequence-specific DNA binding
SRIMR7_RS37075	COG2226	methyltransferase
SRIMR7_RS37120	COG1595	DNA-templated transcription, initiation
SRIMR7_RS37125	COG2188	Transcriptional regulator
SRIMR7_RS37145	COG1940	carbohydrate kinase activity
SRIMR7_RS37160	COG3663	DNA glycosylase
SRIMR7_RS37165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SRIMR7_RS37180	COG0583	DNA-binding transcription factor activity
SRIMR7_RS37220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIMR7_RS37225	COG0577	efflux transmembrane transporter activity
SRIMR7_RS37250	COG2226	methyltransferase
SRIMR7_RS37255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SRIMR7_RS37260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SRIMR7_RS37265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SRIMR7_RS37310	COG0740	serine-type endopeptidase activity
SRIMR7_RS37340	COG0831	urea catabolic process
SRIMR7_RS37345	COG0832	Belongs to the urease beta subunit family
SRIMR7_RS37350	COG0804	urea catabolic process
SRIMR7_RS37355	COG0830	nickel cation binding
SRIMR7_RS37360	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SRIMR7_RS37365	COG0829	nickel cation binding
SRIMR7_RS37375	COG1309	transcriptional regulator
SRIMR7_RS37380	COG0154	amidase activity
SRIMR7_RS37385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS37400	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS37405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS37455	COG0604	alcohol dehydrogenase
SRIMR7_RS37475	COG0431	NADPH-dependent FMN reductase
SRIMR7_RS37500	COG1454	alcohol dehydrogenase
SRIMR7_RS37505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SRIMR7_RS37510	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS37515	COG3903	Transcriptional regulator
SRIMR7_RS37515	COG3629	intracellular signal transduction
SRIMR7_RS37525	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SRIMR7_RS37575	COG0702	epimerase
SRIMR7_RS37590	COG1473	amidohydrolase
SRIMR7_RS37595	COG3135	benzoate transporter
SRIMR7_RS37610	COG2423	ornithine cyclodeaminase activity
SRIMR7_RS37615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIMR7_RS37620	COG3629	intracellular signal transduction
SRIMR7_RS37620	COG3903	Transcriptional regulator
SRIMR7_RS37645	COG1063	alcohol dehydrogenase
SRIMR7_RS37665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SRIMR7_RS37680	COG1609	Transcriptional regulator
SRIMR7_RS37685	COG2222	sugar isomerase
SRIMR7_RS37695	COG1653	transport
SRIMR7_RS37700	COG1175	transmembrane transport
SRIMR7_RS37705	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS37710	COG1793	dna ligase
SRIMR7_RS37715	COG1957	nucleoside hydrolase
SRIMR7_RS37720	COG0477	Major facilitator Superfamily
SRIMR7_RS37725	COG0596	Alpha beta hydrolase
SRIMR7_RS37765	COG0205	6-phosphofructokinase activity
SRIMR7_RS37770	COG3442	glutamine amidotransferase
SRIMR7_RS37780	COG0242	peptide deformylase activity
SRIMR7_RS37790	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS37815	COG0505	Belongs to the CarA family
SRIMR7_RS37820	COG3960	tartronate-semialdehyde synthase activity
SRIMR7_RS37825	COG3622	Belongs to the hyi family
SRIMR7_RS37830	COG2084	Dehydrogenase
SRIMR7_RS37845	COG1131	(ABC) transporter
SRIMR7_RS37895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS37895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS37910	COG2378	regulation of single-species biofilm formation
SRIMR7_RS37940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SRIMR7_RS37950	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SRIMR7_RS37970	COG1191	sigma factor activity
SRIMR7_RS38005	COG2124	cytochrome p450
SRIMR7_RS38035	COG1653	transport
SRIMR7_RS38050	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS38085	COG0395	ABC-type sugar transport system, permease component
SRIMR7_RS38120	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS38140	COG3284	Transcriptional regulator
SRIMR7_RS38155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS38190	COG2197	response regulator
SRIMR7_RS38220	COG1657	PFAM Prenyltransferase squalene oxidase
SRIMR7_RS38240	COG0142	geranyltranstransferase activity
SRIMR7_RS38245	COG1482	cell wall glycoprotein biosynthetic process
SRIMR7_RS38300	COG1012	belongs to the aldehyde dehydrogenase family
SRIMR7_RS38305	COG2197	response regulator
SRIMR7_RS38310	COG4977	sequence-specific DNA binding
SRIMR7_RS38315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SRIMR7_RS38340	COG1063	alcohol dehydrogenase
SRIMR7_RS38345	COG2207	Transcriptional regulator
SRIMR7_RS38355	COG0328	RNA-DNA hybrid ribonuclease activity
SRIMR7_RS38360	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SRIMR7_RS38385	COG1116	anion transmembrane transporter activity
SRIMR7_RS38420	COG1316	TRANSCRIPTIONal
SRIMR7_RS38455	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS38465	COG0829	nickel cation binding
SRIMR7_RS38470	COG4585	Histidine kinase
SRIMR7_RS38475	COG2197	response regulator
SRIMR7_RS38485	COG0438	transferase activity, transferring glycosyl groups
SRIMR7_RS38580	COG2124	cytochrome p450
SRIMR7_RS38595	COG0596	Alpha beta hydrolase
SRIMR7_RS38655	COG0671	phosphoesterase, PA-phosphatase related
SRIMR7_RS38685	COG4221	oxidoreductase activity
SRIMR7_RS38705	COG0110	maltose O-acetyltransferase activity
SRIMR7_RS38730	COG0367	asparagine synthase
SRIMR7_RS38745	COG2124	cytochrome p450
SRIMR7_RS38775	COG0583	DNA-binding transcription factor activity
SRIMR7_RS38795	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS38795	COG0604	alcohol dehydrogenase
SRIMR7_RS38795	COG3321	synthase
SRIMR7_RS38810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SRIMR7_RS38840	COG2732	(Barnase) inhibitor
SRIMR7_RS38915	COG0494	nUDIX hydrolase
SRIMR7_RS38960	COG0596	Alpha beta hydrolase
SRIMR7_RS38965	COG4221	oxidoreductase activity
SRIMR7_RS38990	COG0574	Belongs to the PEP-utilizing enzyme family
SRIMR7_RS38990	COG3848	Pyruvate phosphate dikinase
SRIMR7_RS39025	COG1228	amidohydrolase
SRIMR7_RS39030	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SRIMR7_RS39055	COG4106	trans-aconitate 2-methyltransferase activity
SRIMR7_RS39095	COG2197	response regulator
SRIMR7_RS39140	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
SRIMR7_RS39155	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SRIMR7_RS39165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SRIMR7_RS39195	COG2770	Histidine kinase
SRIMR7_RS39195	COG2208	phosphoserine phosphatase activity
SRIMR7_RS39205	COG2172	sigma factor antagonist activity
SRIMR7_RS39210	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIMR7_RS39215	COG1366	Belongs to the anti-sigma-factor antagonist family
SRIMR7_RS39220	COG1191	sigma factor activity
SRIMR7_RS39250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRIMR7_RS39265	COG2175	clavaminate synthase activity
SRIMR7_RS39280	COG3629	intracellular signal transduction
SRIMR7_RS39280	COG3903	Transcriptional regulator
SRIMR7_RS39295	COG0583	DNA-binding transcription factor activity
SRIMR7_RS39305	COG0189	ligase activity
SRIMR7_RS39370	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS39375	COG2259	Doxx family
SRIMR7_RS39445	COG0154	amidase activity
SRIMR7_RS39450	COG0300	oxidoreductase activity
SRIMR7_RS39460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SRIMR7_RS39500	COG0477	Major facilitator Superfamily
SRIMR7_RS39510	COG2271	Major facilitator Superfamily
SRIMR7_RS39520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SRIMR7_RS39525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS39530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRIMR7_RS39550	COG0346	lactoylglutathione lyase activity
SRIMR7_RS39575	COG0366	Alpha amylase catalytic
SRIMR7_RS39590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRIMR7_RS39600	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS39605	COG2205	protein histidine kinase activity
SRIMR7_RS39610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS39625	COG1131	(ABC) transporter
SRIMR7_RS39645	COG1191	sigma factor activity
SRIMR7_RS39655	COG0596	Alpha beta hydrolase
SRIMR7_RS39660	COG1309	transcriptional regulator
SRIMR7_RS39665	COG0640	Transcriptional regulator
SRIMR7_RS39670	COG0673	inositol 2-dehydrogenase activity
SRIMR7_RS39690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SRIMR7_RS39705	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS39715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SRIMR7_RS39720	COG2124	cytochrome p450
SRIMR7_RS39725	COG2124	cytochrome p450
SRIMR7_RS39785	COG0657	acetylesterase activity
SRIMR7_RS39790	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS39815	COG1960	acyl-CoA dehydrogenase activity
SRIMR7_RS39825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SRIMR7_RS39840	COG0585	pseudouridine synthase activity
SRIMR7_RS39880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS39885	COG3251	PFAM MbtH domain protein
SRIMR7_RS39905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SRIMR7_RS39910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS39920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS39930	COG0789	Transcriptional regulator
SRIMR7_RS39950	COG0745	RESPONSE REGULATOR receiver
SRIMR7_RS39965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SRIMR7_RS39975	COG1181	Belongs to the D-alanine--D-alanine ligase family
SRIMR7_RS39980	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SRIMR7_RS40015	COG2208	phosphoserine phosphatase activity
SRIMR7_RS40015	COG2770	Histidine kinase
SRIMR7_RS40020	COG0596	Alpha beta hydrolase
SRIMR7_RS40025	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS40040	COG1301	dicarboxylic acid transport
SRIMR7_RS40045	COG0473	3-isopropylmalate dehydrogenase activity
SRIMR7_RS40050	COG0583	DNA-binding transcription factor activity
SRIMR7_RS40095	COG0477	Major facilitator Superfamily
SRIMR7_RS40145	COG2205	protein histidine kinase activity
SRIMR7_RS40180	COG0583	DNA-binding transcription factor activity
SRIMR7_RS40185	COG0384	phenazine biosynthesis protein PhzF
SRIMR7_RS40255	COG0137	argininosuccinate synthase activity
SRIMR7_RS40285	COG1028	Short-chain dehydrogenase reductase Sdr
SRIMR7_RS40305	COG0456	acetyltransferase
SRIMR7_RS40305	COG1214	PFAM Peptidase M22, glycoprotease
SRIMR7_RS40325	COG0596	Alpha beta hydrolase
SRIMR7_RS40335	COG2814	Major facilitator Superfamily
SRIMR7_RS40345	COG0697	spore germination
SRIMR7_RS40420	COG1254	Belongs to the acylphosphatase family
SRIMR7_RS40435	COG0604	alcohol dehydrogenase
SRIMR7_RS40440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SRIMR7_RS40480	COG1309	transcriptional regulator
SRIMR7_RS40490	COG0251	oxidation-reduction process
SRIMR7_RS40500	COG2022	thiamine diphosphate biosynthetic process
SRIMR7_RS40500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SRIMR7_RS40555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRIMR7_RS40565	COG0300	oxidoreductase activity
SRIMR7_RS40580	COG2409	Drug exporters of the RND superfamily
SRIMR7_RS40585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SRIMR7_RS40590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRIMR7_RS40595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRIMR7_RS40665	COG0513	Belongs to the DEAD box helicase family
SRIMR7_RS40670	COG1278	Cold shock
SRIMR7_RS40730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SRIMR7_RS40750	COG0300	oxidoreductase activity
SRIMR7_RS40755	COG0583	DNA-binding transcription factor activity
SRIMR7_RS40775	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SRIMR7_RS40780	COG0443	Heat shock 70 kDa protein
SRIMR7_RS40785	COG0484	heat shock protein binding
SRIMR7_RS40870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SRIMR7_RS40875	COG1733	regulation of RNA biosynthetic process
SRIMR7_RS40900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SRIMR7_RS40915	COG4106	trans-aconitate 2-methyltransferase activity
SRIMR7_RS40940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRIMR7_RS40945	COG2197	response regulator
SRIMR7_RS40955	COG2318	DinB family
SRIMR7_RS40965	COG2175	clavaminate synthase activity
SRIMR7_RS40975	COG3479	Phenolic acid decarboxylase
SRIMR7_RS40990	COG2890	protein-(glutamine-N5) methyltransferase activity
SRIMR7_RS41060	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS41120	COG1074	ATP-dependent DNA helicase activity
SRIMR7_RS41165	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SRIMR7_RS41215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SRIMR7_RS41400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SRIMR7_RS41460	COG1309	transcriptional regulator
SRIMR7_RS41590	COG2188	Transcriptional regulator
SRIMR7_RS41715	COG1660	Displays ATPase and GTPase activities
SRIMR7_RS41835	COG1192	Involved in chromosome partitioning
SRIMR7_RS41840	COG1475	DNA binding
SRIMR7_RS41845	COG2801	Transposase and inactivated derivatives
SRIMR7_RS41845	COG3415	Transposase
SRIMR7_RS41860	COG4974	Belongs to the 'phage' integrase family
SRIMR7_RS42075	COG1185	polyribonucleotide nucleotidyltransferase activity
SRIMR7_RS42195	COG4221	oxidoreductase activity
SRIMR7_RS42270	COG2234	aminopeptidase activity
SRIMR7_RS42320	COG2353	YceI-like domain
SRIMR7_RS42325	COG0583	DNA-binding transcription factor activity
SRIMR7_RS42335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SRIMR7_RS42345	COG0431	NADPH-dependent FMN reductase